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Elisabeth Phillips

Senior Research Fellow

BSc(Hons)(Sheffield) PhD(Birmingham)

Email elisabeth.phillips@otago.ac.nz

Tel +64 3 244 1001

Research interests

Dr Elisabeth Phillips is a tumour biologist whose research focuses on the tumour microenvironment, adipocyte-cancer cell interactions, and the molecular mechanisms that drive cancer progression and therapeutic resistance. She uses advanced molecular, cellular, and proteomic approaches to investigate how stromal and adipose tissues influence tumour development, metastasis and treatment response.

Her research programme integrates experimental oncology with translational applications, aiming to develop physiologically relevant models of the tumour microenvironment and to identify novel biomarkers and theapeutic targets that may improve patient outcomes. Through this work, she seeks to advance understanding of the complex interactions between cancer cells and their surrounding tissues, with the goal of informing more effective therapeutic strategies.

Dr Phillips collaborates with interdisciplinary research teams across NEw Zealand and internationally. She is also committed to mentoring emerging researchers and fostering collaborative scientific initiatives that support innovation and excellence in cancer research.

Postgraduate supervision

Current PhD students

Student: Tiffany Ilott
Thesis title: Endometrial cancer risk through development of 3D cell co-culture models
Supervisors: Elisabeth Phillips, George Wiggins, Margaret Currie and Logan Walker

Student: Kate Watson
Thesis title: Investigating the role of obesity in the tumour microenvironment of breast cancer
Supervisors: Elisabeth Phillips and Margaret Currie

Student: Sina Lotz
Thesis title: Investigating the role of ferumoxytol-loaded microphages in iron overload of cancer cells
Supervisors: Gabi Dachs, Citra Praditi, Elisabeth Phillips and Mark Hampton

Completed PhD students

Student: Benjamin Topham
Thesis title: Unravelling the effects of obesity-related compounds on monocyte programming
Supervisors: Margaret Currie, Elisabeth Phillips, George Wiggins and Barry Hock

Student: Eleanor Burgess
Thesis title: The role of ascorbate in glioma
Supervisors: Gabi Dachs, Elisabeth Phillips, Bridget Robinson and Margreet Vissers

Student: Rebekah Crake
Thesis title: Local and systemic effects of adipocyte-secreted factors in breast cancer
Supervisors: Margaret Currie, Elisabeth Phillips, Matthew Strother and Bridget Robinson

Student: Jessika Wise
Thesis title: 3D breast tumour models for drug discovery
Supervisors: Elisabeth Phillips, Khoon Lim, Margaret Currie and Tim Woodfield

Student: Christina Wohlrab
Thesis title: The role of ascorbate in controlling hypoxia factors in renal cell carcinoma  
Supervisors: Gabi Dachs, Elisabeth Phillips, Bridget Robinson and Margreet Vissers

Completed MSc student

Student: Jasmine Curtis
Thesis title: Investigating the impact of adipokines on triple-negative breast cancer cells in 3D culture
Supervisors: Elisabeth Phillips and Margaret Currie
Graduated: 2025

Student: Mohini Puri
Thesis title: Role of cancer associated adipocytes (CAA) and tumour associated collagen structures (TACS) in breast cancer cell invasion and metastasis  
Supervisors: Margaret Currie and Elisabeth Phillips
Graduated: 2019

Completed BBiomedSc(Hons) students

Student: Jasmine Curtis
Thesis title: Adipocyte markers as predictors of prostate cancer progression
Supervisors: Elisabeth Phillips, Arthur Morley-Bunker and Margaret Currie
Graduated: 2015

Student: Rebekah Crake
Thesis title: Exploring molecular links between obesity and breast cancer  
Supervisors: Logan Walker, Elisabeth Phillips and Margaret Currie
Graduated: 2015

Student: Morgan Jones
Thesis title: Does fat provide energy for breast tumour cell invasion and metastasis?  
Supervisors: Margaret Currie, Elisabeth Phillips and Mark Hampton
Graduated: 2015

Student: Anishah Mandani
Thesis title: Development of a metabolic syndrome model of breast cancer  
Supervisors: Gabi Dachs, Elisabeth Phillips and Margaret Currie
Graduated: 2015

Publications

Wise, J. A., Currie, M. J., Woodfield, T. B. F., Lim, K. S., & Phillips, E. (2026). Gelatin-methacryloyl hydrogel stiffness influences epithelial-mesenchymal transition in MCF7 but not MDA-MB-231 breast cancer cells in 3D culture. Biology Open, 15(2), bio062242. doi: 10.1242/bio.062212 Journal - Research Article

Praditi, C., Beverley-Stone, E., Reid, M., Burgess, E. R., Crake, R. L., Vissers, M. C. M., Royds, J. A., Slatter, T. L., Dachs, G. U., & Phillips, E. (2025). Iron content of glioblastoma tumours and role of ferrous iron in the hypoxic response in vitro. Frontiers in Oncology, 15, 1536549. doi: 10.3389/fonc.2025.1536549 Journal - Research Article

Burgess, E. R., Praditi, C., Phillips, E., Vissers, M. C. M., Robinson, B. A., Dachs, G. U., & Wiggins, G. A. R. (2025). Role of sodium-dependent vitamin C transporter-2 and ascorbate in regulating the hypoxic pathway in cultured glioblastoma cells. Journal of Cellular Biochemistry, 126, e30658. doi: 10.1002/jcb.30658 Journal - Research Article

Topham, B., Hock, B., Phillips, E., Wiggins, G., & Currie, M. (2024). The role of innate priming in modifying tumor-associated macrophage phenotype. Frontiers in Bioscience - Landmark, 29(12), 418. doi: 10.31083/j.fbl2912418 Journal - Research Other

Major, G., Ahn, M., C, W.-W., Santos, M., Wise, J., Phillips, E., … Woodfield, T., & Lim, K. S. (2024). Programming temporal stiffness cues within extracellular matrix hydrogels for modelling cancer niches. Materials Today Bio, 25, 101004. doi: 10.1016/j.mtbio.2024.101004 Journal - Research Article

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