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  • Ann Richardson
  • Brian Cox
  • Myles Cockburn
  • Les Toop
  • Terri Green
  • Elisabeth Wells
  • Margaret Sutherland

Supported by the Health Research Council


174 adults aged 20 to 69 who presented to their general practitioners with symptoms of dyspepsia, were randomly allocated to intervention and control groups. In the intervention group, those who were infected with H. pylori and were without other symptoms requiring investigation, were offered eradication therapy. Those who did not have H. pylori infection or who had symptoms requiring investigation, were offered the usual management for their symptoms. The control group was offered the usual management for their symptoms. Both groups have been followed for one year. The results from the trial are now being analysed. The groups will be compared to determine the prevalence of symptoms of dyspepsia at six months and one year, the investigations and treatment offered to the two groups during the study period, and the costs (both health service costs and costs to individuals) for the two groups.


  • Richardson A, Sutherland M, Wells E, Toop L, Plumridge E. Factors affecting general practitioner involvement in a randomised controlled trial in primary care. NZ Med J 2002; 115: 153-5.
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