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BIOC353 Molecular Basis of Health and Disease

Cell signalling: how signals are received and transmitted within cells. Steroid hormone and redox signalling. Regulation of growth, development and cell death. Diseases associated with aberrant cell signalling.

Cell signalling is required for every function of every cell. Aberrant cell signalling underlies all major diseases. Here we explore the biochemical and molecular basis of cell signalling pathways required for growth and development, molecular trafficking, metabolism and cell death. Examples of defective signalling leading to disease include the regulation of the cell cycle and cancer, the role of the cytoskeleton in maintaining cell structure and brain development and the role of redox signalling in cardiovascular disease and neurodegeneration.

Paper title Molecular Basis of Health and Disease
Paper code BIOC353
Subject Biochemistry
EFTS 0.1500
Points 18 points
Teaching period Second Semester
Domestic Tuition Fees (NZD) $1,038.45
International Tuition Fees (NZD) $4,680.00

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BIOC 222 or BIOC 223
Recommended Preparation
BIOC 221
Schedule C
In approved cases BIOC 221 and (ANAT 241 or any 200-level GENE paper or PHSL 231) may be substituted for BIOC 222 or BIOC 223.
This paper is suitable for a broad range of majors who have an interest and basic background in the biochemical basis of cell signalling and cellular functions e.g. Otago's BIOC 223 or similar.
Teaching staff
Professor Sally McCormick
No textbook for this paper.
Graduate Attributes Emphasised
Interdisciplinary perspective, Lifelong learning, Scholarship, Communication, Critical thinking, Ethics, Information literacy, Research, Self-motivation, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes
  • Articulate a broad understanding of contemporary biochemistry, molecular life sciences and related scientific fields
  • Design and execute experiments using contemporary biochemical techniques
  • Identify and critically evaluate relevant information

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Second Semester

Teaching method
This paper is taught On Campus
Learning management system


Stream Days Times Weeks
D1 Tuesday 10:00-10:50 28-34, 36-41
Wednesday 10:00-10:50 28-34, 36-41
E1 Monday 10:00-10:50 36, 39


Stream Days Times Weeks
Attend one stream from
A1 Monday 14:00-17:50 36-41
Tuesday 09:00-09:50 36-41
Tuesday 11:00-17:50 36-41
A2 Thursday 14:00-17:50 36-41
Friday 09:00-09:50 36-41
Friday 11:00-17:50 36-41