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Contact Details

Emeritus Research Professor
Department of Biochemistry
BSc (Cant) MSc PhD (Otago) FRSNZ
Research summary
Cancer Genetics, genomics and cancer biology


Professor Tony Reeve has a notable career in cancer research. His work in the Cancer Genetics Laboratory is focussed on the molecular mechanisms of tumour suppressor genes, growth factors, and imprinted genes. He is internationally recognised for his work on Wilms tumour - a paediatric kidney tumour - demonstrating the importance of tumour suppressor genes, growth factor s such as insulin-like growth factor 2, and the disruption that occurs to the genomic imprinting mechanism of specific genes. He also has an interest in cancer genomics particularly as applied to colorectal cancer. By using high throughput gene expression his group showed that low cellular proliferation and an increased adaptive immune response are both hallmarks of poor prognosis for this disease. In addition to the Cancer Genetics Laboratory Professor Reeve also directs the Otago Genomics Facility which specialises in high throughput gene technologies. He played a lead role in establishing NZ Genome Ltd, an infrastructure which will provide a NZ wide network for genome technologies and biostatistical support.

Professor Reeve is a board member of the Health Research Council (NZ) and chair of the Biomedical Research Committee. He is or has served on several editorial boards including Genes Chromosomes and Cancer, Journal of Pediatric Hematology/Oncology, Genomic Medicine, Genome Letters, NZ Medical Journal and The International DNA Methylation Society.

He was awarded the first medal for Health Research in NZ; the Sir Charles Hercus Medal. He is an Honorary member of the NZ Society of Paediatrics, a Fellow of the Royal Society of NZ and was appointed as an Officer of The NZ Order of Merit for services to medical sciences.


Mehta, S., Wright, D., Black, M. A., Merrie, A., Anjomshoaa, A., Munro, F., Reeve, A., McCall, J., & Print, C. (2022). Impact of clinical data veracity on cancer genomic research. JNCI Cancer Spectrum. doi: 10.1093/jncics/pkac070 Journal - Research Article

Blair, V. R., McLeod, M., Carneiro, F., Coit, D. G., D'Addario, J. L., van Dieren, J. M., … Paringatai, K., Bougen-Zhukov, N., Brew, T., … Godwin, T. D., … Nouri, Y., … Reeve, A. E., & Guilford, P. (2020). Hereditary diffuse gastric cancer: Updated clinical practice guidelines. Lancet Oncology, 21(8), e386-e397. doi: 10.1016/S1470-2045(20)30219-9 Journal - Research Other

Fukuzawa, R., Anaka, M. R., Morison, I. M., & Reeve, A. E. (2017). The developmental programme for genesis of the entire kidney is recapitulated in Wilms tumour. PLoS ONE, 12(10), e0186333. doi: 10.1371/journal.pone.0186333 Journal - Research Article

McInnes, T., Zou, D., Rao, D. S., Munro, F. M., Phillips, V. L., McCall, J. L., Black, M. A., Reeve, A. E., & Guilford, P. J. (2017). Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer. BMC Cancer, 17, 228. doi: 10.1186/s12885-017-3226-4 Journal - Research Article

McInnes, T., Zou, D., Black, M. A., Reeve, A. E., & Guilford, P. J. (2015, August-September). Genome-wide methylation analysis identifies a core set of hypermethylated CpG islands in CIMP-H colorectal cancer. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)

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