EDOR Co-Directors presented research findings at the Healthier Lives National Science Challenge Kōrero Tahi, which was held at Te Papa Tongarewa, Wellington, in February 2024
Associate Professor Justine Camp and Dr Andrew Reynolds discussed the promising results of the Te Kaika DiRECT study, which tested the acceptability and efficacy of a weight loss programme for the remission of type 2 diabetes. The study was conducted in partnership with a Māori health provider in South Dunedin, and co-led by clinician Dr Kim Ma`ia`i.
The Te Kāika DiRECT study recruited 40 participants with obesity and prediabetes or type 2 diabetes who were looking to lose weight. Participants were randomised to either one year of dietitian-supported care or the DiRECT approach to weight loss – three months of total meal replacement (~3400kJ per day) followed by nine months of 
supported weight loss maintenance.
Participants in both groups lost weight, but the DiRECT group lost 3.8kg more on average than those in the dietitian care only group over the 12 months. DiRECT participants also improved their blood sugar control, an important outcome for those with diabetes as it indicates a reduced likelihood of downstream complications and premature mortality.
Before the study, participants spent around 10% of their day in normoglycaemia (the normal or desired range for blood sugar levels). After three months, this increased to 78%, compared with 48% for those receiving usual care. DiRECT participants also had lower blood pressure levels and medication use than the usual care group.
Alongside monitoring clinical health markers, a qualitative study was undertaken by EDOR postgraduate student Kate Campbell to understand participant experiences. They reported that the radically new diet became easier and more acceptable within one week and felt worthwhile when they noticed rapid improvements in their weight and mood.
One of the major themes that emerged from the qualitative study was the invaluable support of the dietitian in helping people in both arms of the study to make changes towards a healthier lifestyle. As well as working with individual study participants, the dietitian worked with their whānau and extended family, which created an additional layer of support.
View the Kōrero Tahi recording
A DiRECT approach to weight loss in Aotearoa, Healthier Lives YouTube, March 2024
Find out more about the Te Kāika Direct study
Te Kāika Direct pilot study, Healthier Lives website, July 2024