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Contact Details

Phone
+64 3 470 9543
Email
greg.jones@otago.ac.nz

University Links

Position
Research Professor and Head of Department of Surgery and Critical Care (Dunedin)
Department
Department of Surgery and Critical Care (Dunedin)
Qualifications
BSc PhD(Otago)
Research summary
Vascular disease genetics, biomarker discovery, and histopathology

Research

Professor Jones' research group has a broad range of interests in the field of vascular biology, including population genetics, cardiovascular disease biomarkers, and vascular connective tissue biology. The group's research has a strong clinical emphasis, particularly in the areas of aortic aneurysm, coronary and peripheral arterial disease and varicose veins.

The Vascular Research Group has four main areas of research focus:

  • Genes associated with the initiation and progression of vascular diseases
  • Identifying circulating biomarkers to assess vascular disease risk
  • The early structural and molecular features of human arterial disease
  • The pathobiology of lower limb venous disease, including varicose veins, venous ulcers and post-operative recurrence
  • The techniques used in the Vascular Research Group include whole genome scanning, microRNA and mRNA microarray, proteomics, immunohistochemistry, cell culture, and functional assays.

The group is currently funded by the Health Research Council of New Zealand.

Publications

Rolleston, A., Jones, G. T., Earle, N. J., Gibbs, S., Pilbrow, A., Faatoese, A., … Cameron, V. A., … Doughty, R. N. (2026). Considerations for study design and analysis for ethically and culturally safe DNA methylation research in Aotearoa New Zealand. SSM Population Health, 33, 101889. doi: 10.1016/j.ssmph.2025.101889 Journal - Research Article

Jones, G. T., Clifford, K., Hill, G. B., Thomas, K. N., Lesche, S., & Krysa, J. (2026). A novel infra-red fluorescence method to identify regions of superficial microvenous reflux in patients with chronic venous disease. Journal of Vascular Surgery: Venous & Lymphatic Disorders, 14(3), 102448. doi: 10.1016/j.jvsv.2026.102448 Journal - Research Article

Jones, G. T., Williams, M. J. A., Khashram, M., Fitzgerald, S., Lyons, O. T. A., Griffin, C. L., Lesche, S., Krysa, J., & Coffey, S. (2026). A DNA methylation marker, cg05575921 (AHRR), outperforms self-reported smoking exposure for its association with cardiovascular disease prevalence. Nicotine & Tobacco Research, 28(3), 422-428. doi: 10.1093/ntr/ntaf165 Journal - Research Article

Cameron, V. A., Jones, G. T., Horwood, L. J., Pilbrow, A. P., Martin, J., Frampton, C., Ip, W. T., Troughton, R. W., Greer, C., Yang, J., Epton, M. J., Harris, S. L., & Darlow, B. A. (2023). DNA methylation patterns at birth predict health outcomes in young adults born very low birthweight. Clinical Epigenetics, 15, 47. doi: 10.1186/s13148-023-01463-3 Journal - Research Article

Roychowdhury, T., Klarin, D., Levin, M. G., Spin, J. M., Rhee, Y. H., Deng, A., … Jones, G. T., … Damrauer, S. M. (2023). Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target. Nature Genetics, 55, 1831-1842. doi: 10.1038/s41588-023-01510-y Journal - Research Article

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