Professor Merilyn Hibma

Rajesh, A., & Hibma, M. (2020). Novel concepts: Langerhans cells in the tumour microenvironment. In A. Birbrair (Ed.), Tumor microenvironment: Hematopoietic cells, part B: Advances in experimental medicine and biology (Vol. 1273). (pp. 147-158). Cham, Switzerland: Springer. doi: 10.1007/978-3-030-49270-0_8

Chapter in Book - Research

Saito, M., Rajesh, A., Innes, C., van der Griend, R., Fitzgerald, P., Simcock, B., Sykes, P., & Hibma, M. (2023). The high-risk human papillomavirus type influences the tissue microenvironment in cervical intraepithelial neoplasia grade 2. Viruses, 15, 1953. doi: 10.3390/v15091953

Journal - Research Article

Aziz, M. A., Seo, B., Hussaini, H. M., Hibma, M., & Rich, A. M. (2022). Comparing two methods for the isolation of exosomes. Journal of Nucleic Acids, 8648373. doi: 10.1155/2022/8648373

Journal - Research Article

Rajesh, A., Saito, M., Morrin, H., Tschirley, A., Simcock, J., Currie, M., & Hibma, M. (2022). Characterisation of the immune microenvironment of cutaneous squamous cell carcinoma in immunosuppression. Experimental Dermatology, 31, 1720-1728. doi: 10.1111/exd.14650

Journal - Research Article

Saito, M., Rajesh, A., Innes, C., van der Griend, R., Fitzgerald, P., Simcock, B., Sykes, P., & Hibma, M. (2022). Blimp-1 is a prognostic indicator for progression of cervical intraepithelial neoplasia grade 2. Journal of Cancer Research & Clinical Oncology, 148, 1991-2002. doi: 10.1007/s00432-022-03993-4

Journal - Research Article

Sykes, P. H., Simcock, B. J., Innes, C. R., Harker, D., Williman, J. A., Whitehead, M., van der Griend, R. A., … Hibma, M., … Petrich, S., … Sadler, L. (2022). Predicting regression of cervical intraepithelial neoplasia grade 2 in women under 25 years. American Journal of Obstetrics & Gynecology, 226, 222.e1-222.e13. doi: 10.1016/j.ajog.2021.09.009

Journal - Research Article

MacDonald, E. J., Geller, S., Sibanda, N., Stevenson, K., Denmead, L., Adcock, A., Cram, F., Hibma, M., & Lawton, B. (2021). Reaching under-screened/never-screened indigenous peoples with human papilloma virus self-testing: A community-based cluster randomised controlled trial. Australian & New Zealand Journal of Obstetrics & Gynaecology, 61, 135-141. doi: 10.1111/ajo.13285

Journal - Research Article

Mohd Zawawi, W. F. A. W., Hibma, M. H., Salim, M. I., & Jemon, K. (2021). Hyperthermia by near infrared radiation induced immune cells activation and infiltration in breast tumor. Scientific Reports, 11(1), 10278. doi: 10.1038/s41598-021-89740-0

Journal - Research Article

Tschirley, A. M., Stockwell, P. A., Rodger, E. J., Eltherington, O., Morison, I. M., Christensen, N., Chatterjee, A., & Hibma, M. (2021). The mouse papillomavirus epigenetic signature is characterised by DNA hypermethylation after lesion regression. Viruses, 13, 2045. doi: 10.3390/v13102045

Journal - Research Article

Dempster-Rivett, K., Innes, C. R., Simcock, B. J., Harker, D., Williman, J. A., Van Der Griend, R. A., Whitehead, M., Hibma, M., … Petrich, S., Faherty, J., … Sykes, P. H. (2020). Evaluation of guidelines for observational management of cervical intraepithelial neoplasia 2 in young women. American Journal of Obstetrics & Gynecology, 223, 408.e1-408.e11. doi: 10.1016/j.ajog.2020.02.029

Journal - Research Article

Rajesh, A., Stuart, G., Real, N., Ahn, J., Tschirley, A., Wise, L., & Hibma, M. (2020). Depletion of langerin⁺ cells enhances cutaneous wound healing. Immunology, 160, 366-381. doi: 10.1111/imm.13202

Journal - Research Article

Adcock, A., Cram, F., Lawton, B., Geller, S., Hibma, M., Sykes, P., … Hart, S. (2019). Acceptability of self-taken vaginal HPV sample for cervical screening among an under-screened Indigenous population. Australian & New Zealand Journal of Obstetrics & Gynaecology, 59, 301-307. doi: 10.1111/ajo.12933

Journal - Research Article

Innes, C. R., Sykes, P. H., Harker, D., Williman, J. A., Van der Griend, R. A., Whitehead, M., Hibma, M., … Petrich, S., Faherty, J., … Simcock, B. J. (2018). Changes in human papillomavirus genotypes associated with cervical intraepithelial neoplasia grade 2 lesions in a cohort of young women (2013–2016). Papillomavirus Research, 6, 77-82. doi: 10.1016/j.pvr.2018.10.010

Journal - Research Article

Zhang, J., Burn, C., Young, K., Wilson, M., Ly, K., Budhwani, M., Tschirley, A., Braithwaite, A., Baird, M., & Hibma, M. (2018). Microparticles produced by human papillomavirus type 16 E7-expressing cells impair antigen presenting cell function and the cytotoxic T cell response. Scientific Reports, 8, 2373. doi: 10.1038/s41598-018-20779-2

Journal - Research Article

Jemon, K., Leong, C.-M., Ly, K., Young, S. L., McLellan, A. D., & Hibma, M. H. (2016). Suppression of the CD8 T cell response by human papillomavirus type 16 E7 occurs in Langerhans cell-depleted mice. Scientific Reports, 6, 34789. doi: 10.1038/srep34789

Journal - Research Article

Warif, N. M. A., Stoitzner, P., Leggatt, G. R., Mattarollo, S. R., Frazer, I. H., & Hibma, M. H. (2015). Langerhans cell homeostasis and activation Is altered in hyperplastic human papillomavirus type 16 E7 expressing epidermis. PLoS ONE, 10(5), e0127155. doi: 10.1371/journal.pone.0127155

Journal - Research Article

Jemon, K., Young, V., Wilson, M., McKee, S., Ward, V., Baird, M., Young, S., & Hibma, M. (2013). An enhanced heterologous virus-like particle for human papillomavirus type 16 tumour immunotherapy. PLoS ONE, 8(6), e66866. doi: 10.1371/journal.pone.0066866

Journal - Research Article

D'Costa, Z. J., Jolly, C., Androphy, E. J., Mercer, A., Matthews, C. M., & Hibma, M. H. (2012). Transcriptional repression of E-cadherin by human papillomavirus type 16 E6. PLoS ONE, 7(11), e48954. doi: 10.1371/journal.pone.0048954

Journal - Research Article

D'Costa, Z. J., Leong, C.-M., Shields, J., Matthews, C., & Hibma, M. H. (2012). Screening of drugs to counteract human papillomavirus 16 E6 repression of E-cadherin expression. Investigational New Drugs, 30(6), 2236-2251. doi: 10.1007/s10637-012-9803-0

Journal - Research Article

Dutton, S., Fleming, S. B., Ueda, N., Heath, D. D., Hibma, M. H., & Mercer, A. A. (2012). Delivery of Echinococcus granulosus antigen EG95 to mice and sheep using recombinant vaccinia virus. Parasite Immunology, 34(6), 312-317. doi: 10.1111/j.1365-3024.2012.01360.x

Journal - Research Article

Hibma, M. H. (2012). The immune response to papillomavirus during infection persistence and regression. Open Virology Journal, 6(Suppl. 2), 241-248. doi: 10.2174/1874357901206010241

Journal - Research Article

Rose, S. B., Lawton, B. A., Lanumata, T. S., Hibma, M., & Baker, M. G. (2012). Predictors of intent to vaccinate against HPV/cervical cancer: A multi-ethnic survey of 769 parents in New Zealand. New Zealand Medical Journal, 125(1350). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Leong, C. M., Doorbar, J., Nindl, I., Yoon, H.-S., & Hibma, M. H. (2010). Loss of epidermal Langerhans cells occurs in human papillomavirus α, γ, and μ but not β genus infections. Journal of Investigative Dermatology, 130(2), 472-480. doi: 10.1038/jid.2009.266

Journal - Research Article

Leong, C.-M., Doorbar, J., Nindl, I., Yoon, H.-S., & Hibma, M. H. (2010). Deregulation of E-cadherin by human papillomavirus is not confined to high-risk, cancer-causing types. British Journal of Dermatology, 163(6), 1253-1263. doi: 10.1111/j.1365-2133.2010.09968.x

Journal - Research Article

Rose, S. B., Lawton, B. A., Lanumata, T., Hibma, M., & Baker, M. G. (2010). HPV/cervical cancer vaccination: Parental preferences on age, place and information needs. Journal of Primary Health Care, 2(3), 190-198.

Journal - Research Article

Hibma, M. H., Real, N. C., Wiles, A., Dobson-Le, D., Dix, B. R., Wynford-Thomas, D., Braithwaite, A. W., & Royds, J. A. (2009). Increased apoptosis and reduced replication efficiency of the E3 region-modified dl309 adenovirus in cancer cells. Virus Research, 145(1), 112-120. doi: 10.1016/j.virusres.2009.06.016

Journal - Research Article

Westphal, D., Ledgerwood, E. C., Tyndall, J. D. A., Hibma, M. H., Ueda, N., Fleming, S. B., & Mercer, A. A. (2009). The orf virus inhibitor of apoptosis functions in a Bcl-2-like manner, binding and neutralizing a set of BH3-only proteins and active Bax. Apoptosis, 14(11), 1317-1330. doi: 10.1007/s10495-009-0403-1

Journal - Research Article

Heinemann, L., Woodfield, L., Amer, M., & Hibma, M. (2008). Effective induction of type 1 helper IgG_2a and cytotoxic T-cell responses in mice following immunization with human papillomavirus type 16 E2 in MF59. Viral Immunology, 21(2), 225-233. doi: 10.1089/vim.2007.0101

Journal - Research Article

Dillon, S., Sasagawa, T., Crawford, A., Prestidge, J., Inder, M. K., Jerram, J., Mercer, A. A., & Hibma, M. (2007). Resolution of cervical dysplasia is associated with T-cell proliferative responses to human papillomavirus type 16 E2. Journal of General Virology, 88, 803-813.

Journal - Research Article

Westphal, D., Ledgerwood, E. C., Hibma, M. H., Fleming, S. B., Whelan, E. M., & Mercer, A. A. (2007). A novel Bcl-2-like inhibitor of apoptosis is encoded by the parapoxvirus orf virus. Journal of Virology, 81(13), 7178-7188.

Journal - Research Article

Royds, J. A., Hibma, M., Dix, B. R., Hananeia, L., Russell, I. A., Wiles, A., … Braithwaite, A. W. (2006). p53 promotes adenoviral replication and increases late viral gene expression. Oncogene, 25, 1509-1520.

Journal - Research Article

Leong, C.-M., & Hibma, M. H. (2005). A flow cytometry-based assay for the measurement of protein regulation of E-cadherin-mediated adhesion. Journal of Immunological Methods, 302, 116-124.

Journal - Research Article

Heinemann, L., Dillon, S., Crawford, A., Bäckström, B. T., & Hibma, M. H. (2004). Flow cytometric quantitation of the protective efficacy of dendritic cell based vaccines in a human papillomavirus type 16 murine challenge model. Journal of Virological Methods, 117, 9-18.

Journal - Research Article

Matthews, K. E., Leong, C. M., Baxter, L., Inglis, E., Yun, K., Bäckström, B. T., … Hibma, M. H. (2003). Depletion of Langerhans cells in human papillomavirus type 16-infected skin is associated with E6-mediated down regulation of E-cadherin. Journal of Virology, 77(15), 8378-8385. doi: 10.1128/JVI.77.15.8378-8385.2003

Journal - Research Article

Middleton, K., Peh, W., Southern, S., Griffin, H., Sotlar, K., Nakahara, T., … Hibma, M. H., … Doorbar, J. (2003). Organization of human papillomavirus productive cycle during neoplastic progression provides a basis for selection of diagnostic markers. Journal of Virology, 77(19), 10186-10201.

Journal - Research Article

Edwards, S. J., Dix, B. R., Myers, C. J., Dobson-Le, D., Huschtscha, L., Hibma, M., Royds, J., & Braithwaite, A. W. (2002). Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14^ARF tumor suppressor genes. Journal of Virology, 76(24), 12483-12490. doi: 10.1128/JVI.76.24.12483-12490.2002

Journal - Research Article

Heinemann, B. L., Dillon, S. M., & Hibma, M. H. (2002). Immunisation with bone marrow-derived dendritic cells presenting HPV-16 E2 protects mice from virus challenge. New Zealand Medical Journal, 115(1159). Retrieved from http://www.nzma.org.nz/journal/115-1159

Journal - Research Article

Hibma, M., & Braithwaite, A. (2001). Viruses to the rescue: p53-based therapies in the fight against cancer. New Zealand Medical Journal, 114(1133), 266-269.

Journal - Research Article

Housawi, F. M., Roberts, G. M., Gilray, J. A., Pow, I., Reid, H. W., Nettleton, P. F., … Hibma, M. H., & Mercer, A. A. (1998). The reactivity of monoclonal antibodies against orf virus with other parapoxviruses and the identification of a 39 kDa immunodominant protein. Archives of Virology, 143(12), 2289-2303.

Journal - Research Article

Stellato, G., Paavonen, J., Nieminen, P., Hibma, M., Vilja, P., & Lehtinen, M. (1997). Diagnostic phase antibody response to the human papillomavirus type 16 E2 protein is associated with successful treatment of genital HPV lesions with systemic interferon α-2b. Clinical & Diagnostic Virology, 7(3), 167-172.

Journal - Research Article

Zatsepina, O., Braspenning, J., Robberson, D., Hajibagheri, M., Blight, K., Ely, S., Hibma, M., … Tommasino, M. (1997). The human papillomavirus type 16 E7 protein is associated with the nucleolus in mammalian and yeast cells. Oncogene, 14(10), 1137-1145.

Journal - Research Article

Gibson-Helm, M., Slater, T., MacDonald, E. J., Stevenson, K., Adcock, A., Geller, S., … Hibma, M., Sykes, P., … Lawton, B. (2023). Te Ara Waiora-Implementing human papillomavirus (HPV) primary testing to prevent cervical cancer in Aotearoa New Zealand: A protocol for a non-inferiority trial. PLoS ONE, 18(3), e0280643. doi: 10.1371/journal.pone.0280643

Journal - Research Other

Hibma, M. H. (2023). Silencing genes in the vaginal mucosa by topical application of a cholesterol-modified siRNA to inhibit HIV transmission. Journal of the European Academy of Dermatology & Venereology, 37(3), 467-468. doi: 10.1111/jdv.18877

Journal - Research Other

Lawton, B., MacDonald, E. J., Storey, F., Stanton, J.-A., Adcock, A., Gibson, M., … King, F., … Watson, H., Bennett, M., Lambert, C. S., Geller, S., Paasi, I., Hibma, M., Sykes, P., Hawkes, D., & Saville, M. (2023). A model for empowering rural solutions for cervical cancer prevention (He Tapu Te Whare Tangata): Protocol for a cluster randomized crossover trial. JMIR Research Protocols, 12, e51643. doi: 10.2196/51643

Journal - Research Other

Speck, P., Mackenzie, J., Bull, R. A., Slobedman, B., Drummer, H., Fraser, J., … Hibma, M., … Ward, V., … Young, P. (2023). Statement in support of: "Virology under the microscope: A call for rational discourse". Journal of Virology. Advance online publication. doi: 10.1128/jvi.00451-23

Journal - Research Other

Ticar, V. S., Tschirley, A., Wilson, M., du Plessis, A., & Hibma, M. (2023). Case report: An adverse response to cyclosporin A treatment in BALB/cJ mice. Laboratory Animals. Advance online publication. doi: 10.1177/00236772231177857

Journal - Research Other

Hibma, M. (2022). Special Issue: HPV and HPV Vaccines. Viruses, 14, 274. doi: 10.3390/v14020274

Journal - Research Other

Rajesh, A., Stuart, G., Real, N., Tschirley, A., Ahn, J., Wise, L., & Hibma, M. (2021). Skin antigen presenting cells and wound healing: New knowledge gained and challenges encountered using mouse depletion models. Immunology, 163, 98-104. doi: 10.1111/imm.13311

Journal - Research Other

Lawton, B., Heffernan, M., Wurtak, G., Steben, M., Lhaki, P., Cram, F., … Hibma, M., Adcock, A., … Garland, S. M. (2020). IPVS Policy Statement addressing the burden of HPV disease for Indigenous peoples. Papillomavirus Research, 9, 100191. doi: 10.1016/j.pvr.2019.100191

Journal - Research Other

Rajesh, A., Wise, L., & Hibma, M. (2019). The role of Langerhans cells in pathologies of the skin. Immunology & Cell Biology, 97(8), 700-713. doi: 10.1111/imcb.12253

Journal - Research Other

Sykes, P., Innes, C., Harker, D., Whitehead, M., van der Griend, R., Lawton, B., Hibma, M., … Petrich, S., Faherty, J., Bergzoll, C., … Parker, C., Sadler, L., & Simcock, B. (2016). Observational management of CIN 2 in young women: A prospective multicenter trial. Journal of Lower Genital Tract Disease, 20(4), 343-347. doi: 10.1097/lgt.0000000000000244

Journal - Research Other

Leong, C. M., Hibma, M., & Tarbotton, J. (2007). Self-applied treatment of persistent plantar wart with 5% imiquimod cream [Letter]. New Zealand Medical Journal, 120(1259). Retrieved from http://journal.nzma.org.nz/journal/120-1259/2668/content.pdf

Journal - Research Other