Profile

Russell, A., Royds, J. A., & Braithwaite, A. W. (2004). Exploitation of cell cycle and cell death controls by Adenoviruses: The road to a productive infection. In C. Alonso (Ed.), Progress in molecular and subcellular biology: Viruses and apoptosis. (pp. 207-243). Berlin: Springer.

Chapter in Book - Research

Braithwaite, A. W., & Edwards, S. J. (2003). The p53 pathway, cancer and aging. In S. C. Kaul & R. Wadhwa (Eds.), Aging of cells in and outside the body. (pp. 121-149). UK: Kluwer Academic.

Chapter in Book - Research

Boix De Jesus, A. N., Taha, A., Wang, D., Mehta, P. M., Mehta, S., Reily-Bell, A., Polwatta Lekamlage, S., Machado Saraiva, A., Tahmeedzaman, T., … Royds, J., Braithwaite, A., Hung, N., & Slatter, T. L. (2023). Increased expression of the Δ133p53ß isoform enhances brain metastasis. International Journal of Molecular Sciences, 24, 1267. doi: 10.3390/ijms24021267

Journal - Research Article

Wiles, A. K., Mehta, S., Millier, M., Woolley, A. G., Li, K., Parker, K., Kazantseva, M., Wilson, M., Young, K., Bowie, S., Ray, S., Slatter, T. L., Stamp, L. K., Hessian, P. A., & Braithwaite, A. W. (2023). Activated CD90/Thy-1 fibroblasts co-express the Δ133p53β isoform and are associated with highly inflamed rheumatoid arthritis. Arthritis Research & Therapy, 25, 62. doi: 10.1186/s13075-023-03040-8

Journal - Research Article

Reinhardt, L. S., Zhang, X., Groen, K., Morten, B. C., De Iuliis, G. N., Braithwaite, A. W., … Avery-Kiejda, K. A. (2022). Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage. Cell Death & Disease, 13, 907. doi: 10.1038/s41419-022-05349-9

Journal - Research Article

Zhang, X., Groen, K., Morten, B. C., Reinhardt, L. S., Campbell, H. G., Braithwaite, A. W., … Avery-Kiejda, K. A. (2022). The effect of p53 and its N-terminally truncated isoform, Δ40p53, on breast cancer migration and invasion. Molecular Oncology, 16, 447-465. doi: 10.1002/1878-0261.13118

Journal - Research Article

Arsic, N., Slatter, T., Gadea, G., Villain, E., Fournet, A., Kazantseva, M., … Mehta, S., … Braithwaite, A., & Roux, P. (2021). Δ133p53β isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells. Nature Communications, 12, 5463. doi: 10.1038/s41467-021-25550-2

Journal - Research Article

Lasham, A., Knowlton, N., Mehta, S. Y., Braithwaite, A. W., & Print, C. G. (2021). Breast cancer patient prognosis is determined by the interplay between TP53 mutation and alternative transcript expression: Insights from TP53 long amplicon digital PCR assays. Cancers, 13(7), 1531. doi: 10.3390/cancers13071531

Journal - Research Article

Chin, C. V., Antony, J., Ketharnathan, S., Labudina, A., Gimenez, G., Parsons, K. M., … Braithwaite, A., Guilford, P., … Horsfield, J. A. (2020). Cohesin mutations are synthetic lethal with stimulation of WNT signaling. eLIFE, 9, e61405. doi: 10.7554/eLife.61405

Journal - Research Article

Eiholzer, R. A., Mehta, S., Kazantseva, M., Drummond, C. J., McKinney, C., Young, K., … Fleming, N., Morrin, H. R., Reader, K., Royds, J. A., Landmann, M., Petrich, S., … Taha, A., Hung, N. A., Slatter, T. L., & Braithwaite, A. W. (2020). Intronic TP53 polymorphisms are associated with increased Δ133TP53 transcript, immune infiltration and cancer risk. Cancers, 12(9), 2472. doi: 10.3390/cancers12092472

Journal - Research Article

Lasham, A., Tsai, P., Fitzgerald, S. J., Mehta, S. Y., Knowlton, N. S., Braithwaite, A. W., & Print, C. G. (2020). Accessing a new dimension in TP53 biology: Multiplex long amplicon digital PCR to specifically detect and quantitate individual TP53 transcripts. Cancers, 12(3), 769. doi: 10.3390/cancers12030769

Journal - Research Article

Mehta, S., Algie, M., Al-Jabry, T., McKinney, C., Kannan, S., Verma, C. S., … Parker, K., Henderson, L., Gould, M. L., Bhatia, P., Harfoot, R., … Kleffmann, T., … Woolley, A. G., … Braithwaite, A. (2020). Critical role for cold shock protein YB-1 in cytokinesis. Cancers, 12, 2473. doi: 10.3390/cancers12092473

Journal - Research Article

Mehta, S., McKinney, C., Algie, M., Verma, C. S., Kannan, S., Harfoot, R., … Gould, M. L., Parker, K., … Cunliffe, H. E., … Kleffmann, T., Braithwaite, A. W., & Woolley, A. G. (2020). Dephosphorylation of YB-1 is required for nuclear localisation during G₂ phase of the cell cycle. Cancers, 12(2), 315. doi: 10.3390/cancers12020315

Journal - Research Article

Weeks, R. J., Ludgate, J. L., Le Mée, G., Khanal, R., Mehta, S., Williams, G., Slatter, T. L., Braithwaite, A. W., & Morison, I. M. (2020). Silencing of Testin expression is a frequent event in spontaneous lymphomas from Trp53-mutant mice. Scientific Reports, 10, 16255. doi: 10.1038/s41598-020-73229-3

Journal - Research Article

Kazantseva, M., Mehta, S., Eiholzer, R. A., Gimenez, G., Bowie, S., Campbell, H., Reily-Bell, A. L., … Ray, S., Drummond, C. J., Reid, G., … Wiles, A., Morrin, H. R., Reader, K. L., Hung, N. A., Baird, M. A., Slatter, T. L., & Braithwaite, A. W. (2019). The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer. Cell Death & Disease, 10, 631. doi: 10.1038/s41419-019-1861-1

Journal - Research Article

Trevarton, A. J., Zhou, Y., Yang, D., Rewcastle, G. W., Flanagan, J. U., Braithwaite, A., … Lasham, A. (2019). Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1. Acta Pharmaceutica Sinica B, 9(5), 997-1007. doi: 10.1016/j.apsb.2018.12.011

Journal - Research Article

Vennin, C., Mélénec, P., Rouet, R., Nobis, M., Cazet, A. S., Murphy, K. J., … Braithwaite, A. W., … Timpson, P. (2019). CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan. Nature Communications, 10, 3637. doi: 10.1038/s41467-019-10968-6

Journal - Research Article

Campbell, H., Fleming, N., Roth, I., Mehta, S., Wiles, A., Williams, G., … Munro, F., McNoe, L., Black, M., McCall, J., Slatter, T. L., … Braithwaite, A. W. (2018). Δ133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling. Nature Communications, 9(1), 254. doi: 10.1038/s41467-017-02408-0

Journal - Research Article

Kazantseva, M., Eiholzer, R. A., Mehta, S., Taha, A., Bowie, S., Roth, I., Zhou, J., … Royds, J. A., Hung, N. A., Slatter, T. L., & Braithwaite, A. W. (2018). Elevation of the TP53 isoform Δ133p53β in glioblastomas: An alternative to mutant p53 in promoting tumour development. Journal of Pathology, 246(1), 77-88. doi: 10.1002/path.5111

Journal - Research Article

Kazantseva, M., Mehta, S., Eiholzer, R. A., Hung, N., Wiles, A., Slatter, T. L., & Braithwaite, A. W. (2018). A mouse model of the Δ133p53 isoform: Roles in cancer progression and inflammation. Mammalian Genome, 29, 831-842. doi: 10.1007/s00335-018-9758-3

Journal - Research Article

Mehta, S. Y., Morten, B. C., Antony, J., Henderson, L., Lasham, A., Campbell, H., Cunliffe, H., Horsfield, J. A., … Braithwaite, A. W. (2018). Regulation of the interferon-gamma (IFN-γ) pathway by p63 and Δ133p53 isoform in different breast cancer subtypes. Oncotarget, 9(49), 29146-29161. doi: 10.18632/oncotarget.25635

Journal - Research Article

Zhang, J., Burn, C., Young, K., Wilson, M., Ly, K., Budhwani, M., Tschirley, A., Braithwaite, A., Baird, M., & Hibma, M. (2018). Microparticles produced by human papillomavirus type 16 E7-expressing cells impair antigen presenting cell function and the cytotoxic T cell response. Scientific Reports, 8, 2373. doi: 10.1038/s41598-018-20779-2

Journal - Research Article

Kazantseva, M., Hung, N. A., Mehta, S., Roth, I., Eiholzer, R., Rich, A. M., Seo, B., Baird, M. A., Braithwaite, A. W., & Slatter, T. L. (2017). Tumor protein 53 mutations are enriched in diffuse large B-cell lymphoma with irregular CD19 marker expression. Scientific Reports, 7, 1566. doi: 10.1038/s41598-017-01800-6

Journal - Research Article

Leroy, B., Ballinger, M. L., Baran-Marszak, F., Bond, G. L., Braithwaite, A., Concin, N., … Soussi, T. (2017). Recommended guidelines for validation, quality control, and reporting of TP53 variants in clinical practice. Cancer Research, 77(6), 1250-1260. doi: 10.1158/0008-5472.can-16-2179

Journal - Research Article

Dasgupta, T., Antony, J., Braithwaite, A. W., & Horsfield, J. A. (2016). HDAC8 inhibition blocks SMC3 deacetylation and delays cell cycle progression without affecting cohesin-dependent transcription in MCF7 cancer cells. Journal of Biological Chemistry, 291(24), 12761-12770. doi: 10.1074/jbc.M115.704627

Journal - Research Article

Lasham, A., Mehta, S. Y., Fitzgerald, S. J., Woolley, A. G., Hearn, J. I., Hurley, D. G., Ruza, I., Algie, M., … Braithwaite, A. W., & Print, C. G. (2016). A novel EGR-1 dependent mechanism for YB-1 modulation of paclitaxel response in a triple negative breast cancer cell line. International Journal of Cancer, 139(5), 1157-1170. doi: 10.1002/ijc.30137

Journal - Research Article

Mehta, S., Tsai, P., Lasham, A., Campbell, H., Reddel, R., Braithwaite, A., & Print, C. (2016). A study of TP53 RNA splicing illustrates pitfalls of RNA-seq methodology. Cancer Research, 76(24), 7151-7159. doi: 10.1158/0008-5472.can-16-1624

Journal - Research Article

Roth, I., Campbell, H., Rubio, C., Vennin, C., Wilson, M., Wiles, A., Williams, G., Woolley, A., … Fleming, N., Baird, M., & Braithwaite, A. W. (2016). The Δ133p53 isoform and its mouse analogue Δ122p53 promote invasion and metastasis involving pro-inflammatory molecules interleukin-6 and CCL2. Oncogene, 35, 4981-4989. doi: 10.1038/onc.2016.45

Journal - Research Article

Slatter, T. L., Wilson, M., Tang, C., Campbell, H. G., Ward, V. K., Young, V. L., … Fleming, N. I., Braithwaite, A. W., & Baird, M. A. (2016). Antitumor cytotoxicity induced by bone-marrow-derived antigen-presenting cells is facilitated by the tumor suppressor protein p53 via regulation of IL-12. OncoImmunology, 5(3), e1112941. doi: 10.1080/2162402X.2015.1112941

Journal - Research Article

Thomson, W. M., Zeng, J., Broadbent, J. M., Foster Page, L. A., Shalev, I., Moffitt, T. E., … Williams, S. M., Braithwaite, A. W., Robertson, S. P., & Poulton, R. (2016). Telomere length and periodontal attachment loss: A prospective cohort study. Journal of Clinical Periodontology, 43(2), 121-127. doi: 10.1111/jcpe.12499

Journal - Research Article

Sawhney, S., Hood, K., Shaw, A., Braithwaite, A. W., Stubbs, R., Hung, N. A., Royds, J. A., & Slatter, T. L. (2015). Alpha-enolase is upregulated on the cell surface and responds to plasminogen activation in mice expressing a Δ133p53α mimic. PLoS ONE, 10(2), e0116270. doi: 10.1371/journal.pone.0116270

Journal - Research Article

Slatter, T. L., Hung, N., Bowie, S., Campbell, H., Rubio, C., Speidel, D., Wilson, M., Baird, M., Royds, J. A., & Braithwaite, A. W. (2015). Δ122p53, a mouse model of Δ133p53α, enhances the tumor-suppressor activities of an attenuated p53 mutant. Cell Death & Disease, 6, e1783. doi: 10.1038/cddis.2015.149

Journal - Research Article

Sun, Y., Bell, J. L., Carter, D., Gherardi, S., Poulos, R. C., Milazzo, G., … Braithwaite, A., & Liu, T. (2015). WDR5 supports an N-Myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma. Cancer Research, 75(23), 5143-5154. doi: 10.1158/0008-5472.CAN-15-0423

Journal - Research Article

Hung, N., Chen, Y.-J., Taha, A., Olivecrona, M., Boet, R., Wiles, A., … Shaw, A., Eiholzer, R., Baguley, B. C., Eccles, M. R., Braithwaite, A. W., MacFarlane, M., Royds, J. A., & Slatter, T. (2014). Increased paired box transcription factor 8 has a survival function in Glioma. BMC Cancer, 14, 159. doi: 10.1186/1471-2407-14-159

Journal - Research Article

Shalev, I., Moffitt, T. E., Braithwaite, A. W., Danese, A., Fleming, N. I., Goldman-Mellor, S., … Poulton, R., Robertson, S. P., … Caspi, A. (2014). Internalizing disorders and leukocyte telomere erosion: A prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder. Molecular Psychiatry, 19, 1163-1170. doi: 10.1038/mp.2013.183

Journal - Research Article

Bildsoe, H., Loebel, D. A. F., Jones, V. J., Hor, A. C. C., Braithwaite, A. W., Chen, Y.-T., … Tam, P. P. L. (2013). The mesenchymal architecture of the cranial mesoderm of mouse embryos is disrupted by the loss of Twist1 function. Developmental Biology, 374, 295-307. doi: 10.1016/j.ydbio.2012.12.004

Journal - Research Article

Campbell, H. G., Mehta, R., Neumann, A. A., Rubio, C., Baird, M., Slatter, T. L., & Braithwaite, A. W. (2013). Activation of p53 following ionizing radiation, but not other stressors, is dependent on the proline-rich domain (PRD). Oncogene, 32(7), 827-836. doi: 10.1038/onc.2012.102

Journal - Research Article

Lasham, A., Print, C. G., Woolley, A. G., Dunn, S. E., & Braithwaite, A. W. (2013). YB-1: Oncoprotein, prognostic marker and therapeutic target? Biochemical Journal, 449, 11-23. doi: 10.1042/bj20121323

Journal - Research Article

Campbell, H. G., Slatter, T. L., Jeffs, A., Mehta, R., Rubio, C., Baird, M., & Braithwaite, A. W. (2012). Does Δ133p53 isoform trigger inflammation and autoimmunity? Cell Cycle, 11(3), 446-450. doi: 10.4161/cc.11.3.19054

Journal - Research Article

Huschtscha, L. I., Napier, C. E., Noble, J. R., Bower, K., Au, A. Y. M., Campbell, H. G., Braithwaite, A. W., & Reddell, R. R. (2012). Enhanced isolation of fibroblasts from human skin explants. Biotechniques, 53(4), 239-244. doi: 10.2144/0000113939

Journal - Research Article

Lasham, A., Samuel, W., Cao, H., Patel, R., Mehta, R., Stern, J. L., … Woolley, A. G., … Black, M. A., Shelling, A. N., Print, C. G., & Braithwaite, A. W. (2012). YB-1, the E2F Pathway, and regulation of tumor cell growth. Journal of the National Cancer Institute, 104(2), 133-146. doi: 10.1093/jnci/djr512

Journal - Research Article

Joshi, S., Braithwaite, A. W., Robinson, P. J., & Chircop, M. (2011). Dynamin inhibitors induce caspase-mediated apoptosis following cytokinesis failure in human cancer cells and this is blocked by Bcl-2 overexpression. Molecular Cancer, 10, 78. doi: 10.1186/1476-4598-10-78

Journal - Research Article

Li, C. G., Nyman, J. E., Braithwaite, A. W., & Eccles, M. R. (2011). PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein. Oncogene, 30, 4824-4834. doi: 10.1038/onc.2011.190

Journal - Research Article

Royds, J. A., Al Nadaf, S., Wiles, A. K., Chen, Y.-J., Ahn, A., Shaw, A., Bowie, S., … Braithwaite, A. W., … Hung, N. A., & Slatter, T. L. (2011). The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival. PLoS ONE, 6(10), e26737. doi: 10.1371/journal.pone.0026737

Journal - Research Article

Slatter, T. L., Hung, N., Campbell, H., Rubio, C., Mehta, R., Renshaw, P., Williams, G., Wilson, M., … Jeffs, A., Royds, J. A., Baird, M. A., & Braithwaite, A. W. (2011). Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoform. Blood, 117(19), 5166-5177. doi: 10.1182/blood-2010-11-321851

Journal - Research Article

Woolley, A. G., Algie, M., Samuel, W., Harfoot, R., Wiles, A., Hung, N. A., … Royds, J. A., Perez, D., Yoon, H.-S., … Braithwaite, A. W. (2011). Prognostic association of YB-1 expression in breast cancers: A matter of antibody. PLoS ONE, 6(6), e20603. doi: 10.1371/journal.pone.0020603

Journal - Research Article

Cohen, S. B., Ma, W., Valova, V. A., Algie, M., Harfoot, R., Woolley, A. G., … Braithwaite, A. W. (2010). Genotoxic stress-induced nuclear localization of oncoprotein YB-1 in the absence of proteolytic processing. Oncogene, 29, 403-410. doi: 10.1038/onc.2009.321

Journal - Research Article

Heinlein, C., Deppert, W., Braithwaite, A. W., & Speidel, D. (2010). A rapid and optimization-free procedure allows the in vivo detection of subtle cell cycle and ploidy alterations in tissues by flow cytometry. Cell Cycle, 9(17), 3584-3590. doi: 10.4161/cc.9.17.12831

Journal - Research Article

Joshi, S., Perera, S., Gilbert, J., Smith, C. M., Mariana, A., Gordon, C. P., … Braithwaite, A. W., & Chircop, M. (2010). The dynamin inhibitors MiTMAB and OcTMAB induce cytokinesis failure and inhibit cell proliferation in human cancer cells. Molecular Cancer Therapeutics, 9(7), 1995-2006. doi: 10.1158/1535-7163.MCT-10-0161

Journal - Research Article

Slatter, T. L., Ganesan, P., Holzhauer, C., Mehta, R., Rubio, C., Williams, G., Wilson, M., Royds, J. A., Baird, M. A., & Braithwaite, A. W. (2010). p53-mediated apoptosis prevents the accumulation of progenitor B cells and B-cell tumors. Cell Death & Differentiation, 17, 540-550. doi: 10.1038/cdd.2009.136

Journal - Research Article

Hancox, R. J., Poulton, R., Welch, D., Olova, N., McLachlan, C. R., Greene, J. M., … Moffitt, T. E., Robertson, S. P., & Braithwaite, A. W. (2009). Accelerated decline in lung function in cigarette smokers is associated with TP53/MDM2 polymorphisms. Human Genetics, 126(4), 559-565. doi: 10.1007/s00439-009-0704-z

Journal - Research Article

Hibma, M. H., Real, N. C., Wiles, A., Dobson-Le, D., Dix, B. R., Wynford-Thomas, D., Braithwaite, A. W., & Royds, J. A. (2009). Increased apoptosis and reduced replication efficiency of the E3 region-modified dl309 adenovirus in cancer cells. Virus Research, 145(1), 112-120. doi: 10.1016/j.virusres.2009.06.016

Journal - Research Article

Huschtscha, L., Moore, J. D., Noble, J. R., Campbell, H. G., Royds, J. A., Braithwaite, A. W., & Reddel, R. R. (2009). Normal human mammary epithelial cells proliferate rapidly in the presence of elevated levels of the tumor suppressors p53 and p21^WAF1/CIP1. Journal of Cell Science, 122(16), 2989-2995. doi: 10.1242/jcs.044107

Journal - Research Article

Jiang, W.-Q., Zhong, Z.-H., Nguyen, A., Henson, J. D., Toouli, C. D., Braithwaite, A. W., & Reddel, R. (2009). Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins. Journal of Cell Biology, 185(5), 797-810. doi: 10.1083/jcb.200810084

Journal - Research Article

Chen, Y.-J., Campbell, H. G., Wiles, A. K., Eccles, M. R., Reddel, R. R., Braithwaite, A. W., & Royds, J. A. (2008). PAX8 regulates telomerase reverse transcriptase and telomerase RNA component in glioma. Cancer Research, 68(14), 5724-5732. doi: 10.1158/0008-5472.CAN-08-0058

Journal - Research Article

Humar, B., McNoe, L., Dunbier, A., Heathcott, R., Braithwaite, A. W., & Reeve, A. E. (2008). Heterogeneous gene expression changes in colorectal cancer cells share the WNT pathway in response to growth suppression by APHS-mediated COX-2 inhibition. Biologics, 2(2), 329-337.

Journal - Research Article

Braithwaite, A. W., & Prives, C. L. (2006). p53: More research and more questions. Cell Death & Differentiation, 13, 877-880.

Journal - Research Article

Braithwaite, A. W., Del Sal, G., & Lu, X. (2006). Some p53-binding proteins that can function as arbiters of life and death. Cell Death & Differentiation, 13, 984-993.

Journal - Research Article

Chen, Y.-J., Hakin-Smith, V., Teo, M., Xinarianos, G. E., Jellinek, D. A., Carroll, T., … Braithwaite, A. W., … Royds, J. A. (2006). Association of mutant TP53 with alternative lengthening of telomeres and favorable prognosis in glioma. Cancer Research, 66(13), 6473-6476.

Journal - Research Article

Royds, J. A., Hibma, M., Dix, B. R., Hananeia, L., Russell, I. A., Wiles, A., … Braithwaite, A. W. (2006). p53 promotes adenoviral replication and increases late viral gene expression. Oncogene, 25, 1509-1520.

Journal - Research Article

Caspi, A., Moffitt, T. E., Cannon, M., McClay, J., Murray, R., Harrington, H., … Braithwaite, A., Poulton, R., & Craig, I. W. (2005). Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: Longitudinal evidence of a gene X environment interaction. Biological Psychiatry, 57(10), 1117-1127.

Journal - Research Article

He, S.-J., Stevens, G., Braithwaite, A. W., & Eccles, M. R. (2005). Transfection of melanoma cells with antisense PAX3 oligonucleotides additively complements cisplatin-induced cytotoxicity. Molecular Cancer Therapeutics, 4(6), 996-1003.

Journal - Research Article

Homer, C., Knight, D. A., Hananeia, L., Sheard, P., Risk, J., Lasham, A., Royds, J. A., & Braithwaite, A. W. (2005). Y-box factor YB1 controls p53 apoptotic function. Oncogene, 24, 8314-8325. Retrieved from http://www.nature.com/onc/journal/v24/n56/abs/1208998a.html

Journal - Research Article

Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., … Martin, J., Braithwaite, A., & Poulton, R. (2003). Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science, 301(5631), 386-389. doi: 10.1126/science.1083968

Journal - Research Article

Edwards, S. J., Hananeia, L., Eccles, M. R., Zhang, Y.-F., & Braithwaite, A. (2003). The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions. Oncogene, 22(29), 4517-4523.

Journal - Research Article

Hall, R. J., Merriman, M. E., Green, R. A., Markham, V. H., Smyth, D. J., Heward, J. M., … Braithwaite, A., … Darlow, B. A., … Harrison, A. A., Highton, J., Hunt, P. J., Manning, P. J., … Scott, R. S., Taylor, B. J., Willis, J., … Merriman, T. R. (2003). The Deleted in Colorectal Carcinoma (DCC) gene 201 R → G polymorphism: No evidence for genetic association with autoimmune disease. European Journal of Human Genetics, 11, 840-844.

Journal - Research Article

Lasham, A., Moloney, S., Hale, T., Homer, C., Zhang, Y. F., Murison, J. G., Braithwaite, A. W., & Watson, J. (2003). The Y-box-binding protein, YB1, is a potential negative regulator of the p53 tumor suppressor. Journal of Biological Chemistry, 278(37), 35516-35523.

Journal - Research Article

Zhang, Y.-F., Homer, C., Edwards, S. J., Hananeia, L., Lasham, A., Royds, J., Sheard, P., & Braithwaite, A. W. (2003). Nuclear localization of Y-box factor YB1 requires wild-type p53. Oncogene, 22, 2782-2794. doi: 10.1038/sj.onc.1206357

Journal - Research Article

Edwards, S. J., Dix, B. R., Myers, C. J., Dobson-Le, D., Huschtscha, L., Hibma, M., Royds, J., & Braithwaite, A. W. (2002). Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14^ARF tumor suppressor genes. Journal of Virology, 76(24), 12483-12490. doi: 10.1128/JVI.76.24.12483-12490.2002

Journal - Research Article

Mill, J. S., Caspi, A., McClay, J., Sugden, K., Purcell, S., Asherson, P., … Braithwaite, A., Poulton, R., & Moffitt, T. E. (2002). The dopamine D4 receptor and the hyperactivity phenotype: A developmental-epidemiological study. Molecular Psychiatry, 7(4), 383-391. doi: 10.1038/sj.mp.4000984

Journal - Research Article

Braithwaite, A. W., & Russell, I. A. (2001). Induction of cell death by adenoviruses. Apoptosis, 6, 359-370.

Journal - Research Article

Dix, B. R., Edwards, S. J., & Braithwaite, A. W. (2001). Does the anti-tumour adenovirus, ONYX-015/dl1520 selectively target cells defective in the p53 pathway? Journal of Virology, 75(12), 5443-5447. doi: 10.1128/JVI.75.12.5443-5447.2001

Journal - Research Article

Hibma, M., & Braithwaite, A. (2001). Viruses to the rescue: p53-based therapies in the fight against cancer. New Zealand Medical Journal, 114(1133), 266-269.

Journal - Research Article

Thomson, W. M., Edwards, S. J., Dobson-Le, D. P., Tompkins, G. R., Poulton, R., Knight, D. A., … Braithwaite, A. W. (2001). IL-1 genotype and adult periodontitis among young New Zealanders. Journal of Dental Research, 80, 1700-1703.

Journal - Research Article

Dix, B. R., O'Carroll, S. J., Myers, C. J., Edwards, S. J., & Braithwaite, A. W. (2000). Efficient induction of cell death by adenoviruses requires binding of E1B55k and p53. Cancer Research, 60, 2666-2672.

Journal - Research Article

Hale, T. K., Myers, C., Maitra, R., Kolzau, T., Nishizawa, M., & Braithwaite, A. W. (2000). Maf transcriptionally activates the mouse p53 promoter and causes a p53-dependent cell death. Journal of Biological Chemistry, 275(24), 17991-17999.

Journal - Research Article

O'Carroll, S. J., Hall, A. R., Myers, C. J., Braithwaite, A. W., & Dix, B. R. (2000). Quantifying adenoviral titers by spectrophotometry. Biotechniques, 28, 408-410.

Journal - Research Article

Hale, T. K., & Braithwaite, A. W. (1999). The adenovirus oncoprotein E1a stimulates binding of the transcription factor ETF to transcriptionally activate the p53 gene. Journal of Biological Chemistry, 274, 23777-23786. doi: 10.1074/jbc.274.34.23777

Journal - Research Article

Kolzau, T., Hansen, R. S., Zahra, D., Reddel, R. R., & Braithwaite, A. W. (1999). Inhibition of SV40 large T antigen induced apoptosis by small T antigen. Oncogene, 18(40), 5598-5603.

Journal - Research Article

Hall, A. R., O'Carroll, S. J., Dix, B. R., & Braithwaite, A. W. (1998). p53 dependent cell death/apoptosis is required for a productive adenovirus infection. Nature Medicine, 4, 1068-1072.

Journal - Research Article

Braithwaite, A., & Poulton, R. (1997). Relevance in health research funding: reality or myth? New Zealand Medical Journal, 110, 361-362.

Journal - Research Article

Hall, A. R., & Braithwaite, A. W. (1997). From clinical significance to significance in the clinic? New Zealand Medical Journal, 110, 347-348.

Journal - Research Article

Ridgway, P. J., Hall, A. R., Myers, C. J., & Braithwaite, A. W. (1997). p53/E1b58kDa complex regulates adenovirus replication. Virology, 237, 404-413.

Journal - Research Article

Hall, A. R., & Braithwaite, A. W. (1996). Culling cancer cells and completing the cell cycle with the tumour suppressor p53. New Zealand BioScience, 4(3), 41-48.

Journal - Research Article

Hansen, R. S., & Braithwaite, A. (1996). The growth inhibitory function of p53 is separable from transactivation, apoptosis and suppression of transformation by E1a and ras. Oncogene, 13(5), 995-1007.

Journal - Research Article

Sedger, L., Ramshaw, I., Condie, A., Medvecsky, J., Braithwaite, A., & Ruby, J. (1996). Vaccinia virus replication is independent of cellular HSP72 expression which is induced during virus infection. Virology, 225(2), 423-427.

Journal - Research Article

Li, K., Ly, K., Mehta, S., & Braithwaite, A. (2022). Importance of crosstalk between the microbiota and the neuroimmune system for tissue homeostasis. Clinical & Translational Immunology, 11, e1394. doi: 10.1002/cti2.1394

Journal - Research Other

Mehta, S., Campbell, H., Drummond, C. J., Li, K., Murray, K., Slatter, T., … Braithwaite, A. W. (2021). Adaptive homeostasis and the p53 isoform network. EMBO Reports, 22, e53085. doi: 10.15252/embr.202153085

Journal - Research Other

Braithwaite, A. W., Royds, J. A., & Jackson, P. (2005). The p53 story: Layers of complexity. Carcinogenesis, 26(7), 1161-1169.

Journal - Research Other