2025
Journal - Research Article
Kumaran, R., Jayawardena, N., Chen, K.-L., Eruera, A.-R., Hodgkinson-Bean, J., Burga, L. N., … Bostina, M. (2025). Cryo-EM structure of the Seneca Valley virus A-particle and related structural states. Journal of Virology. Advance online publication. doi: 10.1128/jvi.00744-25
Hills, F., Jorge, F., Burga, L. N., & Bostina, M. (2025). Expression and purification of SARS-related spike glycoproteins for cryo-EM analysis. Current Protocols, 5(e70115). doi: 10.1002/cpz1.70115
2024
Journal - Research Article
Hills, F. R., Eruera, A.-R., Hodgkinson-Bean, J., Jorge, F., Easingwood, R., Brown, S. H. J., … Burga, L. N., & Bostina, M. (2024). Variation in structural motifs within SARS-related coronavirus spike proteins. PLoS Pathogens, 20(5), e1012158. doi: 10.1371/journal.ppat.1012158
Conference Contribution - Published proceedings: Abstract
Wierenga, J., Morgan, K., Hunter, S., Taylor, H., Argilla, L., Webster, T., Burga, L., Bostina, M., Lim, L., … Geoghegan, J. (2024). Finding the causative agents of infectious diseases affecting hoiho (yellow-eyed penguins) in New Zealand. New Zealand Journal of Zoology, 51(3-4), (pp. 440). doi: 10.1080/03014223.2024.2332118
Conference Contribution - Poster Presentation (not in published proceedings)
Wierenga, J. R., Morgan, K. J., Hunter, S., Taylor, H., Argilla, L. S., Webster, T., Burga, L., Bostina, M., … Dubrulle, J., … Geoghegan, J. L. (2024, September). Genomics-informed diagnostics for infectious disease investigations in the endangered hoiho. Poster session presented at the Queenstown Research Week (QRW) Pathogen Genomics Meeting, Queenstown, New Zealand.
2023
Journal - Research Article
Wierenga, J. R., Grimwood, R., Taylor, H. S., Hunter, S., Argilla, L. S., Webster, T., Lim, L., French, R., … Jorge, F., Bostina, M., Burga, L., … Geoghegan, J. L. (2023). Total infectome investigation of diphtheritic stomatitis in yellow-eyed penguins (Megadyptes antipodes) reveals a novel and abundant megrivirus. Veterinary Microbiology, 286, 109895. doi: 10.1016/j.vetmic.2023.109895
Jadav, N., Velamoor, S., Huang, D., Cassin, L., Hazelton, N., Eruera, A.-R., Burga, L. N., & Bostina, M. (2023). Beyond the surface: Investigation of tumorsphere morphology using volume electron microscopy. Journal of Structural Biology, 215, 108035. doi: 10.1016/j.jsb.2023.108035
Waqqar, S., Lee, K., Lawley, B., Bilton, T., Quiñones‑Mateu, M. E., Bostina, M., & Burga, L. N. (2023). Directed evolution of Seneca Valley virus in tumorsphere and monolayer cell cultures of a small-cell lung cancer model. Cancers, 15, 2541. doi: 10.3390/cancers15092541
Wierenga, J. R., Morgan, K. J., Hunter, S., Taylor, H. S., Argilla, L. S., Webster, T., Dubrulle, J., Jorge, F., Bostina, M., Burga, L., … Geoghegan, J. L. (2023). A novel gyrovirus is abundant in yellow-eyed penguin (Megadyptes antipodes) chicks with a fatal respiratory disease. Virology, 579, 75-83. doi: 10.1016/j.virol.2022.12.012
Conference Contribution - Published proceedings: Abstract
Burga, L., Pham, A., Nimick, M., Waqqar, S., Turner, P., Watanabe, E., & Bostina, M. (2023). Developing oncolytic Seneca Valey Virus for cancer treatment. Proceedings of the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) 50th Anniversary Conference. Retrieved from https://www.nzsbmb.org/conference
Jadav, N., Velamoor, S., Huang, D., Hazelton, N., Eruera, A., Burga, L. N., & Bostina, M. (2023). Beyond the Surface: Ultrastructural Investigation of TS vs ML using vEM. Proceedings of the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) 50th Anniversary Conference. Retrieved from https://www.nzsbmb.org/conference
Kumaran, R., Jayawardena, N., Burga, L., Wolf, M., & Bostina, M. (2023). Structural insights into senecavirus genome uncoating mechanism. Proceedings of the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) 50th Anniversary Conference. Retrieved from https://www.nzsbmb.org/conference
Conference Contribution - Edited volume of conference proceedings
Milne, T., Anwar, M., Burga, L., Harcombe, H., Garelja, M., Middleton, A., Ribeiro, D. C., Fleming, N., Ogbuehi, K., & Bahn, A. (Eds.). (2023). Proceedings of the 268th Otago Medical School Research Society (OMSRS) Meeting: Masters/Honours/Postgraduate Diploma Student Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839
Milne, T., Anwar, M., Burga, L., Harcombe, H., Garelja, M., Middleton, A., Ribeiro, D. C., Fleming, N., Ogbuehi, K., & Bahn, A. (Eds.). (2023). Proceedings of the 267th Otago Medical School Research Society (OMSRS) Meeting: PhD Student Speaker Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839
Milne, T., Anwar, M., Burga, L., Harcombe, H., Garelja, M., Middleton, A., Ribeiro, D. C., Fleming, N., Ogbuehi, K., & Bahn, A. (Eds.). (2023). Proceedings of the 266th Otago Medical School Research Society (OMSRS) Meeting: Research Staff Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839
Milne, T., Anwar, M., Burga, L., Harcombe, H., Garelja, M., Middleton, A., Ribeiro, D. C., Fleming, N., Ogbuehi, K., & Bahn, A. (Eds.). (2023). Proceedings of the 265th Otago Medical School Research Society (OMSRS) Meeting: Summer Student Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839
2022
Journal - Research Article
Jayawardena, N., McCarthy, C., Wang, I., Waqqar, S., Burga, L. N., Strauss, M., & Bostina, M. (2022). Characterisation of a Seneca Valley virus thermostable mutant. Virology, 575, 74-82. doi: 10.1016/j.virol.2022.08.015
Conference Contribution - Edited volume of conference proceedings
Wilson, L., Harcombe, H., Jayakaran, P., Burga, L., Antony, J., Morgaine, K., Garelja, M., Middleton, A., Anwar, M., & Milne, T. (Eds.). (2022). Proceedings of the 264th Otago Medical School Research Society (OMSRS) Meeting: Masters/Honours Student Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839
Wilson, L., Harcombe, H., Jayakaran, P., Burga, L., Antony, J., Morgaine, K., Garelja, M., Middleton, A., Anwar, M., & Milne, T. (Eds.). (2022). Proceedings of the 263rd Otago Medical School Research Society (OMSRS) Meeting: PhD Student Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839
Wilson, L., Harcombe, H., Jayakaran, P., Burga, L., Antony, J., Morgaine, K., Garelja, M., Middleton, A., Anwar, M., & Milne, T. (Eds.). (2022). Proceedings of the 262nd Otago Medical School Research Society (OMSRS) Meeting: Research Staff Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839
Conference Contribution - Poster Presentation (not in published proceedings)
Hills, F. R., Burga, L., Watanabe, E., & Bostina, M. (2022, August). Comparison of the structural and phylogenetic evolution of the Coronaviridae spike protein. Poster session presented at the Advances in Microscopy Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
Watanabe, E., Burga, L., Velamoor, S., Nimick, M., Easingwood, R., & Bostina, M. (2022, August). Effects of Seneca Valley virus with clinically available chemotherapeutic drugs on 3D tumour-like cell cultures of triple negative breast cancer cells. Poster session presented at the Advances in Microscopy Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
Waqqar, S., Jayawardena, N. N., McCarthy, C., Lawley, B., Wang, I., Bilton, T., Burga, L. N., Quinones Mateu, M., … Bostina, M. (2022, August). Obtaining Seneca valley virus variants with increased capsid stability under evolutionary pressure. Poster session presented at the Advances in Microscopy Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Burga, L. N., Pham, A., Nimick, M., Turner, P., Watanabe, E., & Bostina, M. (2022, August). Developing oncolytic Seneca Valley Virus for cancer treatment. Verbal presentation at the Cancer Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
2021
Chapter in Book - Research
Burga, L., & Bostina, M. (2021). Oncolytic Viruses. In D. H. Bamford & M. Zuckerman (Eds.), Encyclopedia of virology (Vol.1). (4th ed.) (pp. 658-661). Amsterdam, The Netherlands: Academic Press. doi: 10.1016/B978-0-12-814515-9.00064-3
Journal - Research Article
Jayawardena, N., Miles, L. A., Burga, L. N., Rudin, C., Wolf, M., Poirier, J. T., & Bostina, M. (2021). N-linked glycosylation on anthrax toxin receptor 1 is essential for Seneca Valley virus infection. Viruses, 13(5), 769. doi: 10.3390/v13050769
Conference Contribution - Published proceedings: Abstract
Watanabe, E., & Burga, L. (2021). Effects of Seneca Valley virus with clinically available chemotherapeutic drugs on 3D tumour-like cell cultures of BT549 triple negative breast cancer cells. New Zealand Medical Journal, 134(1543), (pp. 158). Retrieved from https://www.nzma.org.nz/journal
2020
Journal - Research Article
Velamoor, S., Mitchell, A., Humbel, B. M., Kim, W., Pushparajan, C., Visnovsky, G., Burga, L. N., & Bostina, M. (2020). Visualizing nudivirus assembly and egress. mBio, 11(4), e01333-20. doi: 10.1128/mBio.01333-20
Journal - Research Other
Jayawardena, N., Poirier, J. T., Burga, L. N., & Bostina, M. (2020). Virus-receptor interactions and virus neutralization: Insights for oncolytic virus development. Oncolytic Virotherapy, 9, 1-15. doi: 10.2147/ov.S186337
2019
Journal - Research Article
McCarthy, C., Jayawardena, N., Burga, L. N., & Bostina, M. (2019). Developing picornaviruses for cancer therapy. Cancers, 11(5), 685. doi: 10.3390/cancers11050685
Journal - Research Other
Jayawardena, N., Burga, L. N., Poirier, J. T., & Bostina, M. (2019). Virus-receptor interactions: Structural insights for oncolytic virus development. Oncolytic Virotherapy, 8, 39-56. doi: 10.2147/ov.S218494
2018
Journal - Research Article
Jayawardena, N., Burga, L. N., Easingwood, R. A., Takizawa, K., Wolf, M., & Bostina, M. (2018). Structural basis for anthrax toxin receptor 1 recognition by Seneca Valley Virus. PNAS, 115(46), E10934-E10940. doi: 10.1073/pnas.1810664115
Strauss, M., Jayawardena, N., Sun, E., Easingwood, R. A., Burga, L. N., & Bostina, M. (2018). Cryo-electron microscopy structure of Seneca Valley Virus procapsid. Journal of Virology, 92(6), e01927-17. doi: 10.1128/jvi.01927-17
Conference Contribution - Published proceedings: Abstract
McCarthy, C., Burga, L., & Bostina, M. (2018). Thermal selection of Seneca Valley Virus to reveal residues important for capsid stability. Proceedings of the New Zealand Microbiological Society (NZMS) New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) Joint Annual Conference: Microbes & Molecules. (pp. 93-94). Retrieved from https://www.nzmsconference.org.nz
Strauss, M., Jayawardena, N., Sun, E., Easingwood, R. A., Burga, L. N., & Bostina, M. (2018). Cryo-electron microscopy structure of Seneca Valley Virus procapsid. Proceedings of the New Zealand Microbiological Society (NZMS) New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) Joint Annual Conference: Microbes & Molecules. (pp. 72). Retrieved from https://www.nzmsconference.org.nz
2017
Journal - Research Article
Miles, L. A., Burga, L. N., Gardner, E. E., Bostina, M., Poirier, J. T., & Rudin, C. M. (2017). Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus. Journal of Clinical Investigation, 127(8), 2957-2967. doi: 10.1172/jci93472
Conference Contribution - Published proceedings: Abstract
Jayawardena, N., Burga, L., Easingwood, R., & Bostina, M. (2017). Cryo-electron microscopy investigation of a novel oncolytic virus-receptor complex. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 37-38). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html
Burga, L., McCarthy, C., Rosengren, R., & Bostina, M. (2017). Targeting triple negative breast cancer with the oncolytic Seneca Valley Virus. Proceedings of the New Zealand Microbiological Society (NZMS) Annual Conference. 193. Retrieved from http://www.nzmsconference.org.nz/
Conference Contribution - Poster Presentation (not in published proceedings)
Jayawardena, N., Burga, L., Easingwood, R., & Bostina, M. (2017, September). Cryo-electron microscopy investigation of a novel oncolytic picornavirus-receptor complex. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2016
Conference Contribution - Verbal presentation and other Conference outputs
Bostina, M., Strauss, M., & Burga, L. (2016, November). Genome-capsid interaction in Seneca Valley virus. Verbal presentation at the Joint Meeting of the New Zealand Microbiological Society (NZMS) and the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB), Christchurch, New Zealand.
2013
Journal - Research Article
Israelsen, W. J., Dayton, T. L., Davidson, S. M., Fiske, B. P., Hosios, A. M., Bellinger, G., … Burga, L. N., … Vander Heiden, M. G. (2013). PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells. Cell, 155, 397-409. doi: 10.1016/j.cell.2013.09.025
2012
Journal - Research Article
Juvekar, A., Burga, L. N., Hu, H., Lunsford, E. P., Ibrahim, Y. H., Balmaña, J., … Wulf, G. M. (2012). Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer. Cancer Discovery, 2(11), 1048-1063. doi: 10.1158/2159-8290.CD-11-0336
2011
Journal - Research Article
Yuan, T. L., Wulf, G., Burga, L., & Cantley, L. C. (2011). Cell-to-cell variability in PI3K protein level regulates PI3K-AKT pathway activity in cell populations. Current Biology, 21(3), 173-183. doi: 10.1016/j.cub.2010.12.047
Burga, L. N., Hu, H., Juvekar, A., Tung, N. M., Troyan, S. L., Hofstatter, E. W., & Wulf, G. M. (2011). Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice. Breast Cancer Research, 13, R30. doi: 10.1186/bcr2850
2009
Journal - Research Article
Burga, L. N., Tung, N. M., Troyan, S. L., Bostina, M., Konstantinopoulos, P. A., Fountzilas, H., … Wulf, G. M. (2009). Altered proliferation and differentiation properties of primary mammary epithelial cells from BRCA1 mutation carriers. Cancer Research, 69(4), 1273-1278. doi: 10.1158/0008-5472.can-08-2954
2008
Journal - Research Article
Lam, P. B., Burga, L. N., Wu, B. P., Hofstatter, E. W., Lu, K. P., & Wulf, G. M. (2008). Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability. Molecular Cancer, 7, 91. doi: 10.1186/1476-4598-7-91
2005
Journal - Research Article
Burga, L., Wellmann, F., Lukačin, R., Witte, S., Schwab, W., Schröder, J., & Matern, U. (2005). Unusual pseudosubstrate specificity of a novel 3,5-dimethoxyphenol O-methyltransferase cloned from Ruta graveolens L. Archives of Biochemistry & Biophysics, 440(1), 54-64. doi: 10.1016/j.abb.2005.05.026
