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Teagan Edwards.Research Fellow

BSc(Hons) (Otago), PhD (Otago)

Email teagan.edwards@otago.ac.nz

Dr Teagan Edwards completed her PhD at the Centre for Redox Biology and Medicine. She investigated the structural and functional changes that occur when the inflammatory protein calprotectin is oxidised. She also discovered that calprotectin is degraded into unique fragments at sites of infection and inflammation. These protein fragments were detected in airway fluid from children with cystic fibrosis, a disease in which white blood cells respond to bacterial infection and destroy lung tissue.

She has extensive experience in biomarker research and development using specialised techniques including enzyme-linked immunosorbent assay and mass spectrometry.

Her current project involves exploring the performance of myeloperoxidase, an enzyme released by immune cells to defend against invading pathogens, as a non-invasive biomarker of inflammation in children with inflammatory bowel disease.

Publications

Borichevsky, G. M., Swaminathan, A., Smith, B. R., Edwards, T. S., Ashby, L. V., Frampton, C. M. A., Day, A. S., Gearry, R. B., & Kettle, A. J. (2025). Myeloperoxidase enzyme activity in feces reflects endoscopic severity in inflammatory bowel disease. Inflammatory Bowel Diseases, 31(8), 2254-2268. doi: 10.1093/ibd/izaf109 Journal - Research Article

King-Hudson, T.-R. J., Pearson, A. G., Dunstan-Harrison, C., Powell, M. T., Magon, N. J., Edwards, T. S., Paton, L. N., … Kettle, A. J., Pearson, J. F., Kokaua, J., … Theodore, R., Ramrakha, S., Poulton, R., Moffitt, T. E., Ledgerwood, E. C., & Hampton, M. B. (2025). Biomarkers of oxidative and mitochondrial stress are associated with accelerated pace of aging at midlife in a birth cohort. Journals of Gerontology Series A, 80(7), glaf105. doi: 10.1093/gerona/glaf105 Journal - Research Article

Aitchison, A., Edwards, T., & Day, A. (2025). Simulated gastrointestinal digestion of bovine A1 β-casein does not increase production of inflammatory proteins in vitro compared to A2 β-casein. Journal of Gastroenterology & Hepatology, 40(Suppl. 1), (pp. 26-27). doi: 10.1111/jgh.16899 Conference Contribution - Published proceedings: Abstract

Aitchison, A., Edwards, T. S., & Day, A. S. (2025). Simulated gastrointestinal digestion of milk caseins containing A1 β-casein does not lead to increased production of inflammatory proteins in intestinal epithelial cells in vitro when compared to milk caseins containing A2 β-casein. Journal of Functional Foods, 125, 106669. doi: 10.1016/j.jff.2025.106669 Journal - Research Article

Edwards, T. S., Ho, S. S. C., Brown, S. C., Appleton, L., Smith, B. R., Borichevsky, G. M., Swaminathan, A., Frampton, C. M. A., Gearry, R. B., Kettle, A. J., & Day, A. S. (2025). Fecal myeloperoxidase levels reflect disease activity in children with Crohn’s disease. Inflammatory Bowel Diseases, 31, 800-811. doi: 10.1093/ibd/izae262 Journal - Research Article

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