2026
Journal - Research Article
Dobson, L. J., Hock, B. D., Drabble, A. H. T., Goddard, L., McKenzie, J. L., MacPherson, S. A., & McLellan, A. D. (2026). Enhanced Fc and complement activity of Fc-modified avelumab boosts anti-tumor activity but promotes NK cell fratricide. Clinical & Translational Immunology, 15, e70098. doi: 10.1002/cti2.70098
2025
Journal - Research Article
Hock, B. D., Goddard, L., Dobson, L. J., MacPherson, S. A., O'Donnell, J. L., McKenzie, J. L., & McLellan, A. D. (2025). Impact of rheumatoid factors on the function of therapeutic monoclonals specific for PD-1/PD-L1. Cancer Immunology, Immunotherapy, 74, 216. doi: 10.1007/s00262-025-04078-0
2024
Conference Contribution - Verbal presentation and other Conference outputs
Ashby, L., Flannery, M., McKenzie, J., Magon, N., & Kettle, A. (2024, November). Fluorescent probes as markers of oxidative chemistry inside neutrophil phagosomes. Verbal presentation at the 32nd Meeting of The Society for Redox Research Australasia (SFRRA) and 11th Joint Meeting with The Society for Free Radical Research Japan (SFRRJ), Canberra, Australia.
2023
Journal - Research Article
Hock, B. D., Goddard, L., MacPherson, S. A., Strother, M., Gibbs, D., Pearson, J. F., & McKenzie, J. L. (2023). Levels and in vitro functional effects of circulating anti-hinge antibodies in melanoma patients receiving the immune checkpoint inhibitor pembrolizumab. PLoS ONE, 18(9), e0290793. doi: 10.1371/journal.pone.0290793
Sulit, A. K., Daigneault, M., Allen-Vercoe, E., Silander, O. K., Hock, B., McKenzie, J., Pearson, J., Frizelle, F. A., Schmeier, S., & Purcell, R. (2023). Bacterial lipopolysaccharide modulates immune response in the colorectal tumor microenvironment. npj Biofilms & Microbiomes, 9, 59. doi: 10.1038/s41522-023-00429-w
Conference Contribution - Published proceedings: Abstract
Smith-Diaz, C., Magon, N. J., McKenzie, J. L., Hore, T., Hampton, M. B., Vissers, M. C. M., & Das, A. B. (2023). Transcriptomics and epigenomics analysis of SKM-1 leukaemia response to Vitamin C. Proceedings of the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) 50th Anniversary Conference. Retrieved from https://www.nzsbmb.org/conference
Flannery, M., McKenzie, J., Ashby, L., & Kettle, T. (2023). Interactions between superoxide and myeloperoxidase inside phagocytic neutrophils. Proceedings of the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB) 50th Anniversary Conference. Retrieved from https://www.nzsbmb.org/conference
2022
Conference Contribution - Published proceedings: Abstract
Sulit, A., Daigneault, M., Allen-Vercoe, E., Silander, O., Hock, B., McKenzie, J., Pearson, J., Frizelle, F., … Purcell, R. (2022). Lipopolysaccharide from colorectal cancer-associated bacteria influence cytokine production in immune cells. Colorectal Disease, 24(Suppl. 1), (pp. 55-56). doi: 10.1111/codi.16048
2021
Journal - Research Article
Smith-Díaz, C. C., Magon, N. J., McKenzie, J. L., Hampton, M. B., Vissers, M. C. M., & Das, A. B. (2021). Ascorbate inhibits proliferation and promotes myeloid differentiation in TP53-mutant leukemia. Frontiers in Oncology, 11, 709543. doi: 10.3389/fonc.2021.709543
Conference Contribution - Published proceedings: Abstract
Smith-Díaz, C. C., Magon, N. J., McKenzie, J. L., Hampton, M. B., Vissers, M. C. M., & Das, A. B. (2021). Ascorbate inhibits proliferation and promotes myeloid differentiation in TP53-mutant leukaemia. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 183). Retrieved from https://www.faobmb2021.org
2020
Journal - Research Article
Hock, B. D., McKenzie, J. L., Strother, M., Goddard, L., Butt, L., & Currie, M. J. (2020). Functional effects of immune complexes formed between pembrolizumab and patient-generated anti-drug antibodies. Cancer Immunology, Immunotherapy, 69(12), 2453-2464. doi: 10.1007/s00262-020-02636-2
2019
Journal - Research Article
Hock, B. D., Smith, S. M., McEntyre, C. J., McKenzie, J. L., Sies, C., & Keating, P. E. (2019). Development of a competitive binding homogeneous mobility shift assay for the quantification of adalimumab levels in patient serum. Journal of Immunological Methods, 474, 112672. doi: 10.1016/j.jim.2019.112672
Tang, J. S., Bozonet, S. M., McKenzie, J. L., Anderson, R. F., Melton, L. D., & Vissers, M. C. M. (2019). Physiological concentrations of blueberry-derived phenolic acids reduce monocyte adhesion to human endothelial cells. Molecular Nutrition & Food Research, 63, 1900478. doi: 10.1002/mnfr.201900478
Hock, B. D., Mulholland, K. S., Ganly, P., McKenzie, J. L., Pearson, J. F., & MacPherson, S. A. (2019). Impact of increased access to novel agents on the survival of multiple myeloma patients treated at a single New Zealand centre. Internal Medicine Journal, 49, 598-606. doi: 10.1111/imj.14155
Journal - Research Other
Purcell, R. V., Hock, B. D., Gardner, J., Goddard, L., MacPherson, S. A., & McKenzie, J. L. (2019). Analysis of human papillomavirus infection and leukaemic infiltrate in cutaneous squamous cell carcinoma from patients with chronic lymphocytic leukaemia. British Journal of Haematology, 186(4), e67-e71. doi: 10.1111/bjh.15907
2018
Journal - Research Article
Hock, B. D., McKenzie, J. L., Goddard, L., Smith, S. M., McEntyre, C. J., & Keating, P. E. (2018). Discrimination of anti-drug antibodies with neutralizing capacity in infliximab-and adalimumab-treated patients: Comparison of the homogeneous mobility shift assay and the affinity capture and elution assay. Therapeutic Drug Monitoring, 40(6), 705-715. doi: 10.1097/FTD.0000000000000553
Greer, A. W., McKenzie, J. L., McAnulty, R. W., Huntley, J. F., & McNeilly, T. N. (2018). Immune development and performance characteristics of Romney sheep selected for either resistance or resilience to gastrointestinal nematodes. Veterinary Parasitology, 250, 60-67. doi: 10.1016/j.vetpar.2017.12.013
2017
Journal - Research Article
Hock, B. D., MacPherson, S. A., & McKenzie, J. L. (2017). Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells. PLoS ONE, 12(3), e0172858. doi: 10.1371/journal.pone.0172858
Journal - Research Other
Hock, B. D., McKenzie, J. L., & Keenan, J. I. (2017). Helicobacter pylori outer membrane vesicles inhibit human T cell responses via induction of monocyte COX-2 expression [Short communication]. Pathogens & Disease, 75(4), ftx034. doi: 10.1093/femspd/ftx034
Conference Contribution - Verbal presentation and other Conference outputs
Currie, M., Hock, B., McKenzie, J., Miller, A., Simcock, J., Mackenzie, K., Seddon, A., & Kennedy, B. (2017, July). Functional and prognostic significance of neutrophil subpopulations in cutaneous squamous cell carcinoma. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.
2016
Journal - Research Article
Hock, B. D., McIntosh, N. D., McKenzie, J. L., Pearson, J. F., Simcock, J. W., & MacPherson, S. A. (2016). Incidence of cutaneous squamous cell carcinoma in a New Zealand population of chronic lymphocytic leukaemia patients. Internal Medicine Journal, 46(12), 1414-1421. doi: 10.1111/imj.13261
Seddon, A., Hock, B., Miller, A., Frei, L., Pearson, J., McKenzie, J., Simcock, J., & Currie, M. (2016). Cutaneous squamous cell carcinomas with markers of increased metastatic risk are associated with elevated numbers of neutrophils and/or granulocytic myeloid derived suppressor cells. Journal of Dermatological Science, 83(2), 124-130. doi: 10.1016/j.jdermsci.2016.04.013
2015
Journal - Research Article
Hock, B. D., McKenzie, J. L., Cross, N. B., & Currie, M. J. (2015). Dynamic changes in myeloid derived suppressor cell subsets following renal transplant: A prospective study. Transplant Immunology, 32(3), 164-171. doi: 10.1016/j.trim.2015.05.001
Conference Contribution - Published proceedings: Abstract
Seddon, A. R., Hock, B. D., Miller, A. P., Frei, L. P., Pearson, J. F., McKenzie, J. L., Simcock, J. W., & Currie, M. J. (2015). Neutrophils in cutaneous squamous cell carcinoma: Potential prognostic markers? New Zealand Medical Journal, 128(1421). Retrieved from https://www.nzma.org.nz/journal
Conference Contribution - Poster Presentation (not in published proceedings)
Hock, B. D., McKenzie, J. L., & Keenan, J. I. (2015, November). Helicobacter pylori outer membrane vesicles modulate human immune responses. Poster session presented at the 18th International Conference on Campylobacter, Helicobacter, and Related Organisms (CHRO), Rotorua, New Zealand.
2014
Journal - Research Article
Hock, B. D., MacPherson, S. A., Fernyhough, L. J., & McKenzie, J. L. (2014). Chronic lymphocytic leukemia cells become both activated and immunosuppressive following interaction with CD3 and CD28 stimulated PBMC. Leukemia Research, 38(10), 1217-1223. doi: 10.1016/j.leukres.2014.06.004
2013
Journal - Research Article
Hock, B. D., Fernyhough, L. J., Gough, S. M., & McKenzie, J. L. (2013). Clinical significance of plasma levels of soluble CD40 in patients with chronic lymphocytic leukemia. Open Journal of Blood Diseases, 3(1), 1-5. doi: 10.4236/ojbd.2013.31001
Journal - Research Other
Hock, B. D., & McKenzie, J. L. (2013). Suppression of CD3/CD28 antibody stimulated responses by human granulocytic myeloid-derived suppressor cells: Fact or artefact? Immunology Letters, 152(2), 151-152. doi: 10.1016/j.imlet.2013.05.009
2012
Journal - Research Article
Hock, B. D., Taylor, K. G., Cross, N. B., Kettle, A. J., Hampton, M. B., & McKenzie, J. L. (2012). Effect of activated human polymorphonuclear leucocytes on T lymphocyte proliferation and viability. Immunology, 137(3), 249-258. doi: 10.1111/imm.12004
Hock, B. D., Mackenzie, K. A., Cross, N. B., Taylor, K. G., Currie, M. J., Robinson, B. A., Simcock, J. W., & McKenzie, J. L. (2012). Renal transplant recipients have elevated frequencies of circulating myeloid-derived suppressor cells. Nephrology Dialysis Transplantation, 27(1), 402-410. doi: 10.1093/ndt/gfr264
2011
Journal - Research Article
Glubb, D. M., Gearry, R. B., Barclay, M. L., Roberts, R. L., Pearson, J., Keenan, J. I., McKenzie, J., & Bentley, R. W. (2011). NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease. World Journal of Gastroenterology, 17(23), 2829-2837. doi: 10.3748/wjg.v17.i23.2829
Geertsema, L., Lucas, S. J. E., Cotter, J. D., Hock, B., McKenzie, J., & Fernyhough, L. J. (2011). The cardiovascular risk factor, soluble CD40 ligand (CD154), but not soluble CD40, is lowered by ultra-endurance exercise in athletes. British Journal of Sports Medicine, 45(1), 42-45. doi: 10.1136/bjsm.2008.051896
2010
Journal - Research Article
Hock, B. D., McKenzie, J. L., McArthur, L., Tansley, S., Taylor, K. G., & Fernyhough, L. J. (2010). CD38 as a prognostic marker in chronic lymphocytic leukaemia at a single New Zealand centre: Patient survival in comparison to age and sex matched population data. Internal Medicine Journal, 40(12), 842-849. doi: 10.1111/j.1445-5994.2009.02135.x
Conference Contribution - Published proceedings: Abstract
Wilkinson, T. J., Tweed, M. J., McKenzie, J., Ali, A., Rudland, J., & Egan, A. (2010). Conditional pass facilitates action on professionalism and aligns assessment to learning. Proceedings of the 14th Ottawa Conference: Assessment of Competence in Medicine and the Healthcare Professions. (pp. 189-190). Retrieved from http://www.ottawaconference.org/images/stories/Ottawa_Conference_2010_Abstracts.5.10_1.pdf
2009
Journal - Research Article
Hock, B. D., Fernyhough, L. J., Gough, S. M., Steinkasserer, A., Cox, A. G., & McKenzie, J. L. (2009). Release and clinical significance of soluble CD83 in chronic lymphocytic leukemia. Leukemia Research, 33(8), 1089-1095. doi: 10.1016/j.leukres.2009.01.001
Conference Contribution - Published proceedings: Abstract
Marshall, C. J., Mocatta, T., McKenzie, J., Kettle, A., Blake, J., Elliott, J., Smyth, D., Richards, M., & McClean, D. R. (2009). Acute systemic and local neutrophil and monocyte degranulation prior to primary percutaneous coronary intervention in ST elevation myocardial infarction. JACC, 53(10, Suppl. 1), (pp. A307-A308). [Abstract]
2008
Conference Contribution - Published proceedings: Abstract
Marshall, C., Mocatta, T., McKenzie, J., Kettle, A. J., Blake, J., Elliott, J., Smyth, D., Richards, M., & McClean, D. R. (2008). Increased neutrophil and monocyte degranulation with release of intracellular leucocyte elastase and myeloperoxidase in acute ST elevation myocardial infarction. Heart, Lung & Circulation, 17S, (pp. S2). doi: 10.1016/j.hlc.2008.03.003
Marshall, C., Mocatta, T., McKenzie, J., Kettle, A., Blake, J., Elliott, J., Smyth, D., Richards, M., & McClean, D. (2008). Increased systemic and local neutrophil and monocyte degranulation in patients undergoing primary percutaneous coronary intervention for acute ST elevation myocardial infarction. Heart, Lung & Circulation, 17S, (pp. S106). doi: 10.1016/j.hlc.2008.05.255
Conference Contribution - Verbal presentation and other Conference outputs
Moon, S.-Y., McKenzie, J., Jewell, U., Ganly, P., & Morris, C. (2008, August-September). Identification of novel CNVs in chronic lymphocytic leukaemia using array CGH. Verbal presentation at the Queenstown Molecular Biology Meetings, Queenstown, New Zealand.
2007
Conference Contribution - Published proceedings: Abstract
Moon, S., McKenzie, J., Jewell, U., Ganly, P., & Morris, C. (2007). High-resolution genomic profiling of chronic lymphocytic leukaemia by array CGH. Chromosome Research. 15(Suppl. 1), (pp. 268). [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Moon, S., McKenzie, J., Jewell, U., Ganly, P., & Morris, C. (2007, July). High-resolution genomic profiling of chronic lymphocytic leukaemia by array CGH. Verbal presentation at the 6th European Cytogenetics Conference (ECC), Istanbul, Turkey.
2006
Journal - Research Article
Hock, B. D., McKenzie, J. L., Patton, N. W., Drayson, M., Taylor, K., Wakeman, C., … Albitar, M. (2006). Circulating levels and clinical significance of soluble CD40 in patients with hematologic malignancies. Cancer, 106(10), 2148-2157.
Jarvis, M. D., Rademaker, M. T., Ellmers, L. J., Currie, M. J., McKenzie, J. L., Palmer, B. R., Frampton, C. M., Richards, A. M., & Cameron, V. A. (2006). Comparison of infarct-derived and control ovine cardiac myofibroblasts in culture: Response to cytokines and natriuretic peptide receptor expression profiles. American Journal of Physiology: Heart & Circulatory Physiology, 291, H1952-H1958. doi: 10.1152/ajpheart.00764.2005
Hock, B. D., Drayson, M., Patton, W. N., Taylor, K., Kerr, L., McKenzie, J. L., & on behalf of the Working Party on Leukaemia in Adults. (2006). Circulating levels and clinical significance of soluble CD86 in myeloma patients. British Journal of Haematology, 133, 165-172.
Hock, B. D., O'Donnell, J. L., Taylor, K., Steinkasserer, A., McKenzie, J. L., Rothwell, A. G., & Summers, K. L. (2006). Levels of the soluble forms of CD80, CD86, and CD83 are elevated in the synovial fluid of rheumatoid arthritis patients. Tissue Antigens, 67(1), 57-60. doi: 10.1111/j.1399-0039.2005.00524.x
Conference Contribution - Published proceedings: Abstract
Moon, S. Y., McKenzie, J., Walker, L., McDonald, M., Ganly, P., & Morris, C. M. (2006). High throughput screening of genomic copy number changes in chronic lymphocytic leukaemia using array comparative genomic hybridisation. In L. Griffiths (Ed.), Proceedings of the 11th International Congress of Human Genetics. (pp. 149). [Abstract]
2005
Journal - Research Article
Hock, B. D., Roberts, G., McKenzie, J. L., Gokhale, P., Salm, N., McLellan, A. D., Patton, N. W., & Roake, J. A. (2005). Exposure to the electrofusion process can increase the immunogenicity of human cells. Cancer Immunology, Immunotherapy, 54, 880-890.
2004
Journal - Research Article
Hock, B. D., Starling, G. C., Patton, W. N., Salm, N., Bond, K., McArthur, L. T., & McKenzie, J. L. (2004). Identification of a circulating soluble form of CD80: Levels in patients with hematological malignancies. Leukemia & Lymphoma, 45(10), 2111-2118. doi: 10.1080/10428190410001712199
Hock, B. D., Haring, L. F., Steinkasserer, A., Taylor, K. G., Patton, W. N., & McKenzie, J. L. (2004). The soluble form of CD83 is present at elevated levels in a number of hematological malignancies. Leukemia Research, 28, 237-241.
Conference Contribution - Published proceedings: Abstract
Jarvis, M. D., Rademaker, M. T., Ellmers, L. J., Palmer, B. R., Frampton, C. M., Gunningham, S. P., Currie, M. J., McKenzie, J. L., … Cameron, V. A. (2004). Cytokine induced changes in cultured cardiac fibroblasts: Cell morphology and natriuretic peptide receptor expression. Proceedings of the 12th International Congress of Endocrinology. (pp. 145). [Abstract]
2003
Journal - Research Article
Hock, B. D., McKenzie, J., Patton, W. N., Haring, L., Yang, Y., Shen, Y., … Albitar, M. (2003). The clinical significance of soluble CD86 levels in patients with acute myeloid leukemia and myelodysplastic syndrome. Cancer, 98, 1681-1688.
Copland, M., Baird, M. A., Rades, T., McKenzie, J., Becker, B., Reck, F., … Davies, N. M. (2003). Liposomal delivery of antigen to human dendritic cells. Vaccine, 21, 883-890.
2001
Journal - Research Article
Summers, K. L., Hock, B. D., McKenzie, J. L., & Hart, D. N. J. (2001). Phenotypic characterization of five dendritic cell subsets in human tonsils. American Journal of Pathology, 159, 285-295.
Hock, B. D., Kato, M., McKenzie, J., & Hart, D. N. J. (2001). A soluble form of CD83 is released from activated dendritic cells and B lymphocytes, and is detectable in normal human sera. International Immunology, 13(7), 959-967.
1997
Journal - Research Article
Mannering, S. I., McKenzie, J. L., Fearnley, D. B., & Hart, D. N. J. (1997). HLA-DR1-restricted BCR-ABL (B3A2)-specific CD4(+) T lymphocytes respond to dentritic cells pulsed with B3A2 peptide and antigen-presenting cells exposed to B3A2 containing cell lysates. Blood, 90(1), 290-297.
Haematology Research Group Leader