Current students
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Grace Borichevsky | Understand and predict disease activity in inflammatory bowel disease | Tony Kettle, Richard Gearry |
| Eleanor Burgess | The role of ascorbate in glioma | Gabi Dachs, Elisabeth Phillips, Margreet Vissers, Bridget Robinson |
| Tess Featherston | Exploiting oxidative stress in the treatment of metastatic melanoma | Martina Paumann-Page, Mark Hampton |
| Oscar Graham | Nanopore sequencing of GBA | Martin Kennedy,, John Pearson, Tim Anderson |
| Sarah Heath | Molecular analysis of p16 amyloid formation | Christoph Goebl, Mark Hampton |
| HyunWoo Jun | Developing low risk potting mix products to protect gardeners from Legionnaires' disease. | Sandy Slow, Steve Chambers |
| Jaslyn Kee | The application of pharmacogenetics to understanding adverse drug reactions | Martin Kennedy, Simran Maggo |
| Ayush Kumar | Hydrogen sulfide and substance P in acute pancreatitis | Madhav Bhatia, Steve Chambers |
| Xihua Lian | Invasive aspergillosis | Madhav Bhatia, Aamir Raja, Steve Chambers, John Lewis |
| Sumeet Manandhar | The role of H2S and substance P in NF-B level expression in polmicrobial sepsis | Madhav Bhatia, Steve Chambers |
| Hadley Northcott | Allele-specific expression analysis of BRCA1/2 variants in breast cancer patients. | Logan Walker, Vanessa Lattimore |
| Citra Praditi | Vitamin C and metastasis | Margreet Vissers, Gabi Dachs |
| Carlos Smith Diaz | Effect of nutrition and oxidative stress on epigenetic regulation during cellular differentiation and development | Margreet Vissers, Andrew Das, Mark Hampton, Tim Hore |
| Cassie Stylianou | Copy variants and endometrial cancer risk | Logan Walker, John Pearson |
| Eveline van Leeuwen | Oxidative stress and redox regulation of the cytoskeleton | Mark Hampton, Margreet Vissers |
| Jessika Wise | 3D breast tumour models for drug discovery | Elisabeth Phillips, Tim Woodfield, Associate Professor Khoon Lim, Margaret Currie |
| Zhixing Zhu | The role of exosome miRNA in acute lung injury | Madhav Bhatia, Steve Chambers, Xiangdong Wang, Yiming Zeng |
BBiomedSc(Hons)
| Student | Thesis title | Supervisor(s) |
|---|---|---|
| Eira Beverley-Stone | The role of iron in brain cancer | Gabi Dachs |
| Alex Botha | Investigating the amyloid state of p16 | Christoph Goebl, Kenny Chitcholtan, Mark Hampton, Vanessa Morris |
| Mackenzie Flannery | Observing heterogeneity in neutrophil phagosomes | Tony Kettle, Louisa Ashby |
| Shaya Helem | Identifying the mechanism of action of a marine-derived anticancer compound | Mark Hampton, Paul Pace, Stephanie Bozonet |
| Tiffany Ilott | Functional analysis of copy number variants associated with endometrial cancer | Logan Walker, George Wiggins, Arthur Morley-Bunker |
| Ashleigh Monson | Potential transcriptional adaptation associated with BRCA1 pathogenic variants | George Wiggins, Logan Walker |
| Jackson O'Neill | Allelic diversity of the pharmacogene CYP2C19 in Pasifika people | Martin Kennedy, John Pearson |
| Anh Thu Phan | The microbiome in IBD-related colorectal cancer | Rachel Purcell, Arthur Morley-Bunker, Logan Walker |
| Briana Smith | Investigating the redox state of p16 | Christoph Goebl, Mark Hampton, Nick Magon, Vanessa Morris |
| Georgia Turner | Human cytomegalovirus (HCMV) in breast tumour samples | Arthur Morley-Bunker, Margaret Currie, Logan Walker |
2021
PhD
BBiomedSc(Hons)
| Student | Thesis title | Supervisor(s) |
|---|---|---|
| Leonie Hitchman | Allelic diversity of the pharmacogene CYP2D6 in Māori and Pasifika | Simran Maggo, Martin Kennedy, John Pearson |
| Samantha Meredith | Characterising the role of peroxidasin in breast cancer | Martina Paumann-Page |
| Jenny Naughton | Identification of key peptide regions in the amyloid state of the tumour suppressor p16 | Christoph Goebl, Nick Magon, Mark Hampton |
| Ruth Phang | Nutritional immunity: Butyrate and colon carcinogenesis | Jacqui Kennan, Andrew Day, Mark Hampton |
| Ben Topham | Investigating the relationship between ascorbate and the differentiation of monocytes in an in-vitro melanoma model | Margaret Currie |
2020
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Bee Bathish | Characterising the activity of peroxidasin in the extracellular matrix | Christine Winterbourn, Tony Kettle |
| Rebekah Crake | Local and systemic effects of adipocyte-secreted factors in breast cancer | Margaret Currie, Elisabeth Phillips, Bridget Robinson, Matthew Strother |
| Yusmiati (Cen) Liau | Application of second and third generation sequencing in pharmacogenetics | Martin Kennedy, Simran Maggo, Simone Cree, John Pearson |
| Ali Mohammadi | Development of detection methods for Legionella longbeachae in clinical and environmental samples | Steve Chambers, David Murdoch, Amy Scott-Thomas |
| Arthur Morley-Bunker | Scoping for RNA biomarkers of colorectal cancer | Logan Walker, Margaret Currie, John Pearson, Mr Tim Eglinton |
BBiomedSc(Hons)
| Student | Thesis title | Supervisor(s) |
|---|---|---|
| Madison Hill | The interaction of neutrophils and amyloid-ß in Alzheimer's disease | Leon Smyth, Mark Hampton |
| Jess Permain | Bacterial lipopolysaccharide and immune activation in colorectal cancer | Rachel Purcell, Logan Walker |
| Carlos Smith Diaz | Vitamin C as an epigenetic therapeutic for acute myeloid leukaemia | Andrew Das, Margreet Vissers, Mark Hampton |
2019
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Priyanka Sinha | Transcriptional effects of mood stabiliser drugs in a serotonergic cell line | Martin Kennedy, Simone Cree, John Pearson |
| Masuma Zawari | Bioavailability and biological effects of isothiocyanates from broccoli sprout powder | Mark Hampton, Anitra Carr, Andree Pearson, Dion Thompson |
BBiomedSc(Hons)
| Student | Thesis title | Supervisor(s) |
|---|---|---|
| Krista Dawson | Characterising the relationship between Legionella longbeachae and their amoebal hosts: Implications for Legionnaires' disease prevention | Sandy Slow, Steve Chambers, Trevor Anderson, David Murdoch |
| Tess Featherston | Peroxiredoxins as biomarkers of oxidative stress in metastatic melanoma cells | Mark Hampton, Martina Paumann-Page, Christine Winterbourn |
| Lorna Forrester | Mycobacterial resistance to neutrophil oxidants | Mark Hampton, Heather Parker |
| Jaya Montecillo | Gene modification of breast cancer cells for cancer imaging | Gabi Dachs |
2018
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Teagan Hoskin | Oxidative post-translational modifications of calprotectin during inflammation | Tony Kettle, Nina Dickerhof, Richard Gearry, Andrew Day |
| Kate Vick | Peroxiredoxin expression and redox state in human cancers | Mark Hampton, Christine Winterbourn |
| Christina Wohlrab | The role of ascorbate in controlling hypoxia factors in renal cell carcinoma | Gabi Dachs, Elisabeth Phillips, Margreet Vissers, Bridget Robinson |
BBiomedSc(Hons)
2017
PhD
BBiomedSc(Hons)
| Student | Thesis title | Supervisor |
|---|---|---|
| Leah Butt | Measuring markers of immune response in patients treated with Nivolumab (Opdivo) or Pembrolizumab (Keytruda) | Margaret Currie |
2016
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Abel Ang | Role of endogenous hydrogen sulfide synthesised by cystathionine-gamma-lyase in the inflammatory response in acute pancreatitis | Madhav Bhatia, Greg Giles |
| Sarah Appleby | Telomere length as a putative biomarker of health and disease | Martin Kennedy, Mark Hampton, John Pearson |
| Alireza Badiei | Effect of cystathionine-gamma-lyase gene silencing with siRNA on inflammation in acute pancreatitis | Madhav Bhatia, Steve Chambers |
| Janice Chew-Harris | Biomarkers of kidney function; Validity of estimates in clinical practice | Chris Florkowski, Peter George |
| Aaron Stevens | The interaction of G-Quadruplex DNA structure and cytosine methylation | Martin Kennedy, Simone Cree |
BBiomedSc(Hons)
| Student | Thesis title | Supervisors |
|---|---|---|
| Rosie Burn | A validation study to detect markers of proliferation adequacy in the endometrium | Martin Kennedy, Gloria Evans, John Evans |
| Linda Buss | The influence of exercise and hyperlipidaemia on breast cancer | Gabi Dachs, Margreet Vissers |
| Lucy de Jong | Diagnostic applications of a Nanopore sequencing device | Martin Kennedy |
| Tara Swadi | A novel strategy to prevent bacterial biofilm formation using methylthioadenosine-nucleosidase inhibitors | Steve Chambers |
2015
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Diana Balasubramanain | Gene expression changes induced by mood stabilizer drugs in a serotonergic cell line | Martin Kennedy, Peter Joyce, Mark Hampton |
| Simone Bayer | Redox State Of Erythrocyte Peroxiredoxin 2 During Oxidative Stress And Its Effect On Membrane Binding | Christine Winterbourn, Mark Hampton |
| Lizzie Campbell | Regulation of Hypoxia-Inducible Factor-Mediated Tumour Growth by Ascorbate | Gabi Dachs, Bridget Robinson, Margreet Vissers |
| Eng Wee Chua | Understanding Adverse Drug Reactions Using Genomic Sequencing | Martin Kennedy, Ruth Savage |
| Tony Rahman | Venous thromboembolism in patients with cancer undertaking chemotherapy | Bridget Robinson, Margaret Currie, Mark Smith |
| Usha Rani Talla (Pujary) | The Effect of Hypoxia on Neutrophil Survival and Function | Margreet Vissers, Mark Hampton, Heather Parker |
BBiomedSc(Hons)
| Student | Thesis title | Supervisors |
|---|---|---|
| Mark Brinsden | Measuring Mitochondrial Dysfunction in Humans | Andree Pearson, Mark Hampton |
| Rebekah Crake | Exploring Molecular Links between Obesity and Breast Cancer | Logan Walker, Margaret Currie, Elisabeth Phillips |
| Sarah Drake | Investigating the pro-apoptotic properties of portimine | Mark Hampton |
| Melanie Hamzah | Inactivation of a Thiol-Dependent Enzyme by Urate Hydroperoxide | Tony Kettle, Mark Hampton |
| Morgan Jones | Does fat provide energy for breast tumour cell invasion and metastasis? | Margaret Currie, Elisabeth Phillips, Mark Hampton |
| Anishah Mandani | Development of a metabolic syndrome mouse model of breast cancer | Gabi Dachs, Margaret Currie, Elisabeth Phillips |
| Millie Taylor | Impact of G-quadruplex structures and DNA methylation on allelic drop-out during in vitro amplification of imprinted genes | Martin Kennedy, Simone Cree |
2014
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| James Falvey | Macrophage Migration Inhibitory Factor and Inflammatory Bowel Disease | Richard Gearry, Mark Hampton, Rebecca Roberts |
| Rebecca Poynton | Peroxiredoxin 3 and oxidative stress in mitochondria | Mark Hampton, Christine Winterbourn, Andrea Betz |
BBiomedSc(Hons)
| Student | Thesis Title | Supervisor |
|---|---|---|
| Bee Bathish | The effect of cell metabolism on epigenetic processes in cancer cells | Margreet Vissers |
| Masuma Zawari | Involvement of mitochondria and peroxiredoxin in TNF-mediated necroptosis | Mark Hampton |
2013
PhD
*Divisional Exceptional Thesis
BBiomedSc(Hons)
| Student | Thesis title | Supervisors |
|---|---|---|
| Teresa Flett | Gene transfer to restore vitamin C synthesis in human cell line | Gabi Dachs, Margreet Vissers |
| Zac Gerring | Evaluating molecular markers of breast tumour progression | Logan Walker, Gavin Harris |
| Annika Seddon | Immune suppression and squamous cell carcinoma tumour biology | Margaret Currie |
| Kate Vick | Functional consequences of lowering mitochondrial peroxiredoxin 3 expression | Mark Hampton |
2012
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Shrawan Bhandari | Investigation of the biosynthesis of 2-Pentylfuran from 'Aspergillus fumigatus in vitro' and 'in vivo' | Steve Chambers, Amy Scott-Thomas, Chris Charles, Richard Weld |
2011
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Melanie Coker* | The role of reactive chlorine species in bacterial killing by neutrophils | Prof Tony Kettle, Christine Winterbourn |
| Sarah Deng | Gene regulation by antidepressant drugs | Martin Kennedy, Peter Joyce |
| Alice Johnstone | Implications for drug addiction development from expressional analyses of rattus norvegicus striatal tissue following methamphetamine and benzylpiperazine exposure | Martin Kennedy |
| Vikas Kumar | Oxidative changes in cardiac proteome during ischemia/reperfusion | Christine Winterbourn, Mark Hampton |
| Amy (Marshall) Osborne* | Assessment of genetic variation in the threatened New Zealand sea lion, Phocarctos hookeri, and its association with fitness | Neil Gemmell, Martin Kennedy |
| Katya Volkova | Tumour angiogenesis : the role of metabolic syndrome and insulin resistence | Margaret Currie, Gabi Dachs, Bridget Robinson |
* Divisional Exceptional Thesis
BBiomedSc(Hons)
| Student | Thesis title | Supervisors |
|---|---|---|
| Lizzie Campbell | Hydrogen Sulfide: Investigation into the Effects of Different H2S Donors on the Upregulation of Inflammatory Cytokines | Madhav Bhatia |
| Teagan Hoskin | Neutrophil Activation in Inflammatory Bowel Disease | Richard Gearry, Prof Tony Kettle |
| Sarah Jodczyk (Appleby) | Establishment and validation of a telomere length assay | Martin Kennedy |
| Emma Spencer | Inhibiting the pro-inflammatory cytokine MIF | Mark Hampton |
2010
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Ryan Davis* | The molecular basis of fibrinogen disease: Structure, function and pathology | Stephen Brennan, Peter George |
| Michelle Hunt | Vessel-directed enzyme-prodrug therapy for cancer | Gabi Dachs, Margaret Currie, Bridget Robinson |
| Kasia Mackenzie | Why are skin cancers more aggressive in renal transplant recipients? | Margaret Currie, Barry Hock, Bridget Robinson, Gabi Dachs, Andrew Miller, Justin Roake, Mr Jeremy Simcock |
| Karina O'Connor | The effect of oxidative stress on DNA methylation | Mark Hampton, Christine Winterbourn, Anthony Reeve |
| Melissa Stacey | Cell antioxidant pathways for disposal of MPO-derived oxidants | Christine Winterbourn, Margreet Vissers |
* Divisional Exceptional Thesis
BBiomedSc(Hons)
| Student | Thesis title | Supervisor |
|---|---|---|
| Andrew Gibb | Does promoter variation in the USP46 gene influence antidepressant response? | Martin Kennedy |
| Min-Hi Han | Assessing a blood biomarker of lung infection | Christine Winterbourn |
| Aaron Hayes | Detecting 2-aminoacetophenone and pyocyanin from clinical strains of Pseudomonas aeruginosa | Amy Scott-Thomas |
| Hannah Kennedy | Development of an assay for interferon beta bioavailability in relapsing-remitting MS patients | Stephen Brennan |
| Tamas Major | Evaluation of The Four-and-a-half LIM 2 (FHL2) Single Polypeptide As A Potential Biomarker of Cardio-Renal Syndrome (CRS) | Chris Pemberton |
| Anna van Pomeren | Myeloid-Derived Suppressor Cells, Tumour Angiogenesis, and Cancer Progression | Margaret Currie |
2009
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Michael Bland | Genetic and functional analysis of novel serotonergic candidate genes in psychiatric disorders | Martin Kennedy, Peter Joyce, Rebecca Roberts |
| Kristin Brown* | Cellular targets of isothiocyanates | Mark Hampton, Christine Winterbourn, Sarah Cuddihy |
| Andy Cox* | Peroxiredoxin 3 and the regulation of mitochondrial hydrogen peroxide | Mark Hampton, Christine Winterbourn, Sarah Cuddihy |
| Dylan Glubb | Pharmacogenomics of the antidepressant Paroxetine | Martin Kennedy, Peter Joyce |
| Jessie Green* | Oxidant production inside the phagosomes of neutrophils | Christine Winterbourn, Tony Kettle, Mark Hampton |
* Divisional Exceptional Thesis
2008
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Sarah Gunningham | The role of vascular endothelial growth factors and their receptors in breast and colorectal tumour angiogenesis | Margaret Currie, Vicky Cameron, Bridget Robinson, Stephen Fox |
| Tim Harwood | Glutathione sulfonamide as a biomarker of oxidative stress during inflammation | Christine Winterbourn, Tony Kettle |
| Felicia Low | The antioxidant activity of erythrocyte peroxiredoxin 2 and its role in protecting haemoglobin | Christine Winterbourn, Mark Hampton |
| So-Young Moon | Identification of genetic aberrations in chronic lymphocytic leukaemia using array CGH | Margaret Currie, Peter Ganly, Christine Morris |
| Campbell Sheen | Molecular characterisation of coagulation disorders | Stephen Brennan, Christine Morris, Mark Smith |
| Selma Stuffrein-Roberts | Allelic expression patterns in psychiatric candidate genes | Martin Kennedy, Vicky Cameron, Michael Eccles |
| Rachel Wilkie | Oxidative stress and apoptosis in the phagocytic neutrophils | Mark Hampton, Margreet Vissers |
2007
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Mathew Littlejohn | Pharmacogenetics of the B2 adrenergic receptor and related molecules | Martin Kennedy, Prof Tony Kettle, |
| Robyn Midwinter | The role of chloramines on the inflammatory process in endothelial cells | Christine Winterbourn, Margreet Vissers, |
| Logan Walker | Genetic aberrations in breast cancer | Bridget Robinson, Christine Morris |
2006
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Amy Dear | Assembly and secretion of Fibrinogen: Evidence from human mutation | Stephen Brennan, Peter George |
| Patrick McHugh | A cellular model for investigating antidepressant pharmacogenomics | Martin Kennedy, Peter Joyce, Geraldine Rogers |
| Jennifer Scotter | The laboratory diagnosis of invasive aspergillosis | Stephen Chambers, Peter Ganly, David Murdoch |
| Malina Storer | Development of laboratory tests for assessing vitamin status | Stephen Chambers, Michael Lever |
2005
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Vickie Hanrahan | The role of homeobox gene HLX1 in haematopoiesis and leukaemia | Martin Kennedy, Stephen Brennan, Geraldine Rogers |
2004
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| James Baty | Hydrogen peroxide-sensitive thiol proteins: Potential targets in redox signalling | Christine Winterbourn, Mark Hampton, |
| Warwick Dellow | Glycine Betaine and Diabetes Mellitus | Stephen Chambers, Peter George, Dr Michael Lever |
| Ghassan Maghzal | The effects of genes and the environment on the structure and function of fibrinogen | Stephen Brennan, Peter George |
2003
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Fook Choe Cheah | Lung inflammation and oxidative injury in hyaline membrane disease: The role of NF-kB activation in pulmonary leukocytes | Christine Winterbourn, Brian Darlow |
| Sheryl Gough | Molecular analysis of a novel chromosome translocation associated with acute lymphoid leukemia | Peter Ganly, Christine Morris |
| Harold Neal | CRESCENTIC GLOMERULONEPHRITIS: Associations of Eosinophils and Transforming Growth Factors | Robin Fraser |
2002
PhD
| Student | Thesis title | Supervisors |
|---|---|---|
| Suzanne Benjes | BCR-ABL1 Recombination Mechanisms in Chronic Myeloid Leukaemia: Clues from Complexity | Vicky Cameron, Christine Morris |
| Sangeeta Budhia | Isolation and Characterisation of Novel Human Dendritic Cell-Associated Molecule, DD1.1 | Barry Hock, Martin Kennedy, Justin Roake |
| Anna Chapman | Aggregation and chlorination of proteins by hypochlorous acid: Insights into reactions within neutrophils | Tony Kettle, Porf Christine Winterbourn |
| Victoria Metcalf | The Molecular Evolution of Serum Albumin in Non-Mammalian Vertebrate Species | Stephen Brennan, Peter George |