2023
Journal - Research Article
Appleby, S., Frampton, C., Holdaway, M., Chew-Harris, J., Liew, O. W., Chong, J. P. C., Lewis, L., Troughton, R., … Richards, A. M., & Pemberton, C. J. (2023). Circulating erythroferrone has diagnostic utility for acute decompensated heart failure in patients presenting with acute or worsening dyspnea. Frontiers in Cardiovascular Medicine, 10, 1195082. doi: 10.3389/fcvm.2023.1195082
2022
Journal - Research Article
Lewis, L. K., Raudsepp, S. D., Whitlow, J. C., Appleby, S., Pemberton, C. J., Yandle, T. G., & Richards, A. M. (2022). Assays specific for BNP1-32 and NT-proBNP exhibit a similar performance to two widely used assays in the diagnosis of heart failure. Clinical Chemistry, 68(10), 1292-1301. doi: 10.1093/clinchem/hvac126
Wu, Z., Pilbrow, A. P., Liew, O. W., Chong, J. P. C., Sluyter, J., Lewis, L. K., Lasse, M., Frampton, C. M., … Cameron, V. A., … Richards, A. M. (2022). Circulating cardiac biomarkers improve risk stratification for incident cardiovascular disease in community dwelling populations. EBioMedicine, 82, 104170. doi: 10.1016/j.ebiom.2022.104170
Conference Contribution - Published proceedings: Abstract
Lewis, L., Raudsepp, S., Whitlow, J., Appleby, S., Pemberton, C., & Richards, A. M. (2022). Do more specific assays for B-type natriuretic peptides better predict heart failure in breathless patients than the currently used assays? European Heart Journal, 43(Suppl. 1), (pp. i76). doi: 10.1093/eurheartj/ehab849.060
Conference Contribution - Poster Presentation (not in published proceedings)
Lewis, L. (2022, August). Assays specific for BNP1-32 and NT-proBNP exhibit a similar performance to two widely used assays in the diagnosis of heart failure. Poster session presented at the Metabolic & Cardiovascular Disease Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
2021
Journal - Research Article
Lassé, M., Pilbrow, A. P., Kleffmann, T., Andersson Överström, E., von Zychlinski, A., Frampton, C. M. A., … Troughton, R. W., Lewis, L. K., Prickett, T. C. R., Pemberton, C. J., Richards, A. M., & Cameron, V. A. (2021). Fibrinogen and hemoglobin predict near future cardiovascular events in asymptomatic individuals. Scientific Reports, 11(1), 4605. doi: 10.1038/s41598-021-84046-7
Conference Contribution - Published proceedings: Abstract
Holdaway, M., Lewis, L., Chew-Harris, J., Richards, M., Pemberton, C., & Appleby, S. (2021). Erythroferrone can diagnose acute decompensated heart failure in patients presenting with breathlessness. Heart, Lung & Circulation, 30(Suppl. 2), (pp. S76). doi: 10.1016/j.hlc.2021.05.044
2020
Journal - Research Article
Harris, S. L., Troughton, R., Lewis, L., Austin, N., & Pemberton, C. (2020). Circulating forms of B-type natriuretic peptide in very preterm infants. Journal of Applied Laboratory Medicine, 5(3), 506-515. doi: 10.1093/jalm/jfaa003
Journal - Research Other
Lewis, L. K., Raudsepp, S. D., Prickett, T. C. R., Yandle, T. G., Pemberton, C. J., & Richards, A. M. (2020). ProBNP processing is decreased by obesity in patients with heart failure. Annals of Translational Medicine, 8(4), 135. doi: 10.21037/atm.2019.12.81
Conference Contribution - Published proceedings: Abstract
Lewis, L., Raudsepp, S. D., Yandle, T. G., Frampton, C. M., Richards, A. M., Prickett, T. C. R., … Pemberton, C. J. (2020). ProBNP glycosylation of threonine 71 is increased with obesity in patients with heart failure. European Heart Journal, 41(Suppl. 1), ehz872.007. doi: 10.1093/ehjci/ehz872.007
2019
Journal - Research Article
Lewis, L. K., Raudsepp, S. D., Prickett, T. C. R., Yandle, T. G., Doughty, R. N., Frampton, C. M., Pemberton, C. J., & Richards, A. M. (2019). ProBNP that is not glycosylated at threonine 71 is decreased with obesity in patients with heart failure. Clinical Chemistry, 65(9), 1115-1124. doi: 10.1373/clinchem.2019.302547
2017
Journal - Research Article
Lewis, L. K., Raudsepp, S. D., Yandle, T. G., Prickett, T. C., & Richards, A. M. (2017). Development of a BNP1-32 immunoassay that does not cross-react with proBNP. Clinical Chemistry, 63(6), 1110-1117. doi: 10.1373/clinchem.2016.269712
2016
Conference Contribution - Poster Presentation (not in published proceedings)
Lewis, L. K., Raudsepp, S. D., Yandle, T. G., & Richards, A. M. (2016, August). Development of a specific immunoassay to measure BNP1-32 in plasma without the confounding influences of precursor peptides and peptide metabolites: Could this improve heart failure diagnosis? Poster session presented at the Medical Sciences Congress (MedSci), Nelson, New Zealand.
2015
Journal - Research Article
Justice, T. D., Hammer, G. L., Davey, R. J., Paramalingam, N., Guelfi, K. J., Lewis, L., … Fournier, P. A. (2015). Effect of antecedent moderate-intensity exercise on the glycemia-increasing effect of a 30-sec maximal sprint: A sex comparison. Physiological Reports, 3(5), 12386. doi: 10.14814/phy2.12386
2014
Journal - Research Article
Lewis, L. K., Yandle, T. G., Hilton, P. J., Jensen, B. P., Begg, E. J., & Nicholls, M. G. (2014). Endogenous ouabain is not ouabain. Hypertension, 64, 680-683. doi: 10.1161/hypertensionaha.114.03919
Mahagamasekera, P. G., Ruygrok, P. N., Palmer, S. C., Richards, A. M., Ansell, G. S., Nicholls, M. G., Pemberton, C. J., Lewis, L. K., & Yandle, T. G. (2014). B-type natriuretic peptide forms within the heart, coronary sinus, and peripheral circulation in humans: Evidence for degradation before secretion. Clinical Chemistry, 60(3), 549-558. doi: 10.1373/clinchem.2013.210435
Journal - Research Other
Lewis, L. K., Yandle, T. G., Hilton, P. J., Jensen, B. P., Begg, E. J., & Nicholls, M. G. (2014). [Response to letter re Endogenous ouabain is not ouabain]. Hypertension, 64. Retrieved from http://hyper.ahajournals.org/content/64/4/680/reply#hypertensionaha_el_351
2013
Journal - Research Article
Adem, A., Al Haj, A., Benedict, S., Yasin, J., Nagelkerke, N., Nyberg, F., Yandle, T. G., Frampton, C. M., Lewis, L. K., Nicholls, M. G., & Kazzam, E. (2013). ANP and BNP responses to dehydration in the one-humped camel and effects of blocking the renin-angiotensin system. PLoS ONE, 8(3), e57806. doi: 10.1371/journal.pone.0057806
Lewis, L. K., Raudsepp, S. D., Yandle, T. G., Frampton, C. M., Palmer, S. C., Troughton, R. W., & Richards, A. M. (2013). Comparison of immunoassays for NTproBNP conducted on three analysis systems: Milliplex, Elecsys and RIA. Clinical Biochemistry, 46(4-5), 388-390. doi: 10.1016/j.clinbiochem.2012.11.022
Conference Contribution - Poster Presentation (not in published proceedings)
Byers, M. S., Bailey, M., Siriwardena, M., Lewis, L. K., Oliver, J., Troughton, R., Richards, A. M., & Pemberton, C. J. (2013, August). Plasma ghrelin signal peptide can exclude co-existent pneumonia in acute decompensated heart failure. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2012
Journal - Research Article
Ali, M. A., Adem, A., Chandranath, I. S., Benedict, S., Pathan, J. Y., Nagelkerke, N., … Lewis, L. K., Yandle, T. G., Nicholls, M. G., Frampton, C. M., & Kazzam, E. (2012). Responses to dehydration in the one-humped camel and effects of blocking the renin-angiotensin system. PLoS ONE, 7(5), e37299. doi: 10.1371/journal.pone.0037299
Scott, N. J. A., Cameron, V. A., Raudsepp, S., Lewis, L. K., Simpson, E. R., Richards, A. M., & Ellmers, L. J. (2012). Generation and characterization of a mouse model of the metabolic syndrome: Apolipoprotein E and aromatase double knockout mice. American Journal of Physiology: Endocrinology & Metabolism, 302, E576-E584. doi: 10.1152/ajpendo.00222.2011
Evans, J. J., Chitcholtan, K., Dann, J. M., Guilford, P., Harris, G., Lewis, L. K., Nagase, J., … Sykes, P. H. (2012). Adrenomedullin interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades. Gynecologic Oncology, 125(1), 214-219. doi: 10.1016/j.ygyno.2011.12.429
Braithwaite, J. E., Yandle, T. G., Nicholls, M. G., & Lewis, L. K. (2012). Interference by o-phenanthroline in the radioimmunoassay of angiotensin II in small volume blood samples. Clinical Biochemistry, 45(1-2), 168-170. doi: 10.1016/j.clinbiochem.2011.10.008
2011
Journal - Research Article
Rademaker, M. T., Charles, C. J., Ellmers, L. J., Lewis, L. K., Nicholls, M. G., & Richards, A. M. (2011). Prolonged urocortin 2 administration in experimental heart failure: Sustained hemodynamic, endocrine, and renal effects. Hypertension, 57, 1136-1144. doi: 10.1161/HYPERTENSIONAHA.111.173203
Troughton, R. W., Lewis, L. K., Yandle, T. G., Pemberton, C. J., & Nicholls, M. G. (2011). B-type natriuretic peptides: Looking to the future. Annals of Medicine, 43(3), 188-197. doi: 10.3109/07853890.2010.526630
2009
Journal - Research Article
Nicholls, M. G., Lewis, L. K., Yandle, T. G., Lord, G., Mckinnon, W., & Hilton, P. J. (2009). Ouabain, a circulating hormone secreted by the adrenals, is pivotal in cardiovascular disease. Fact or fantasy? Journal of Hypertension, 27(1), 3-8. doi: 10.1097/HJH.0b013e32831101d1
2003
Journal - Research Article
Nicholls, M. G., Charles, C. J., Lainchbury, J. G., Lewis, L. K., Rademaker, M. T., Richards, A. M., & Yandle, T. G. (2003). Adrenomedullin in heart failure. Hypertension Research, 26(Suppl.), S135-S140. doi: 10.1291/hypres.26.S135
Evans, J. J., Youssef, A. H., Yandle, T. G., Lewis, L. K., & Nicholls, M. G. (2003). Endothelin-1 directly modulates its own secretion: Studies utilising the cell immunoblot technique. Regulatory Peptides, 113, 149-153.
2002
Journal - Research Article
Evans, J. J., Youssef, A. H., Yandle, T. G., Lewis, L. K., & Nicholls, M. G. (2002). Effects of endothelin-1 on release of adrenomedullin and C-type natriuretic peptide from individual human vascular endothelial cells. Journal of Endocrinology, 175, 225-232.
Rademaker, M. T., Charles, C. J., Cooper, G. J. S., Coy, D. H., Espiner, E. A., Lewis, L. K., Nicholls, M. G., & Richards, A. M. (2002). Combined angiotensin-converting enzyme inhibition and adrenomedullin in an ovine model of heart failure. Clinical Science, 102(6), 653-660.
Rademaker, M. T., Charles, C. J., Cooper, G. J. S., Coy, D. H., Espiner, E. A., Lewis, L. K., Nicholls, M. G., & Richards, A. M. (2002). Combined endopeptidase inhibition and adrenomedullin in sheep with experimental heart failure. Hypertension, 39(1), 93-98.
2001
Journal - Research Article
Nicholls, M. G., Lainchbury, J. G., Lewis, L. K., McGregor, D. O., Richards, A. M., Troughton, R. W., & Yandle, T. G. (2001). Bioactivity of adrenomedullin and proadrenomedullin N-terminal 20 peptide in a man. Peptides, 22, 1745-1752.
Nicholls, M. G., Lainchbury, J. G., Lewis, L. K., McGregor, D. O., Richards, A. M., Troughton, R. W., & Yandle, T. G. (2001). Bioactivity of adrenomedullin and proadrenomedullin N-terminal 20 peptide in man. Peptides, 22(11), 1745-1752.
Troughton, R. W., Frampton, C. M., Lewis, L. K., Yandle, T. G., Richards, A. M., & Nicholls, M. G. (2001). Differing thresholds for modulatory effects of adrenomedullin infusion on hemodynamic and hormone responses to angiotensin II and adrenocorticotrophic hormone in healthy volunteers. Clinical Science, 101, 103-109.
Conference Contribution - Published proceedings: Abstract
Evans, J. J., Youssef, A. H., Yandle, T. G., Lewis, L. K., & Nicholls, M. G. (2001). Individual human vascular endothelial cells contain and secrete both adrenomedullin and endothelin. Proceedings of the New Zealand Society of Endocrinology Scientific Meeting. (pp. 4). [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Rademaker, M. T., Charles, C. J., Lewis, L. K., Espiner, E. A., Nicholls, M. G., & Richards, A. M. (2001). Combined adrenomedullin adminstration and angiotensin-converting enzyme inhibition in experimental heart failure. Verbal presentation at the 34th International Congress of Physiological Sciences, Christchurch.
Rademaker, M. T., Charles, C. J., Espiner, E. A., Lewis, L. K., Nicholls, M. G., & Richards, A. M. (2001, August). Combined adrenomedullin administration and angiotensin-converting enzyme inhibition in experimental heart failure. Verbal presentation at the 34th International Congress of Physiological Sciences, Christchurch, New Zealand.
2000
Journal - Research Article
Troughton, R. W., Lewis, L. K., Yandle, T. G., Richards, A. M., & Nicholls, M. G. (2000). Hemodynamic, hormone, and urinary effects of adrenomedullin infusion in essential hypertension. Hypertension, 36, 588-593.
Lainchbury, J. G., Troughton, R. W., Lewis, L. K., Yandle, T. G., Richards, A. M., & Nicholls, M. G. (2000). Haemodynamic, hormonal and renal effects of short-term adrenomedullin infusion in healthy volunteers. Journal of Clinical Endocrinology & Metabolism, 85, 1016-1020.
Conference Contribution - Verbal presentation and other Conference outputs
Rademaker, M. T., Charles, C. J., Cooper, G. J. S., Coy, D. H., Espiner, E. A., Lewis, L. K., Nicholls, M. G., Pemberton, C. J., & Richards, A. M. (2000, October). Combined adrenomedullin administration and neutral endopeptidase inhibitor in heart failure. Verbal presentation at the 4th Annual Meeting of the Society for Cardiovascular Endocrinology and Metabolism, Australia.
Troughton, R. W., McGregor, D. O., Charles, C. J., Lewis, L. K., Yandle, T., Richards, A. M., & Nicholls, M. G. (2000). Biological effects of adrenomedullin infusion in healthy volunteers, essential hypertension and chronic renal failure. Verbal presentation at the 2nd International Symposium on Adrenomedullin and PAMP, Japan.
1999
Journal - Research Article
Lainchbury, J. G., Nicholls, M. G., Espiner, E. A., Yandle, T. G., Lewis, L. K., & Richards, A. M. (1999). Bioactivity and interactions of adrenomedullin and brain natriuretic peptide in patients with heart failure. Hypertension, 34(1), 70-75.
Charles, C. J., Lainchbury, J. G., Lewis, L. K., Rademaker, M. T., Richards, A. M., Yandle, T. G., & Nicholls, M. G. (1999). The role of adrenomedullin. American Journal of Hypertension, 12(2 Part 1), 166-173.
Conference Contribution - Published proceedings: Abstract
Lainchbury, J. G., Troughton, R. W., Lewis, L. K., Yandle, T. G., Espiner, E. A., Nicholls, M. G., & Richards, A. M. (1999). Low and high dose adrenomedullin infusion in normal volunteers. 72nd Scientific Sessions, American Heart Foundation. 100(18), (pp. I-350). Circulation. [Abstract]
1998
Journal - Research Article
Lewis, L. K., Smith, M. W., Yandle, T. G., Richards, A. M., & Nicholls, M. G. (1998). Adrenomedullin (1-52) measured in human plasma by radioimmunoassay: plasma concentration, adsorption and storage. Clinical Chemistry, 44(3), 571-577.
Lai, K. N., Leung, J. C., Yeung, V. T. F., Lewis, L. K., & Nicholls, M. G. (1998). Gene transcription and synthesis of adrenomedullin by cultured human renal cells. Biochemical & Biophysical Research Communications, 244(2), 567-572.
Conference Contribution - Verbal presentation and other Conference outputs
Lainchbury, J. G., Rademaker, M. T., Charles, C. J., Lewis, L. K., Yandle, T. G., Richards, A. M., & Nicholls, M. G. (1998). Adrenomedullin in heart failure. Verbal presentation at the Centre of Excellence International Symposium on Adrenomedullin and PAMP, Osaka, Japan.
1997
Journal - Research Article
Rademaker, M. T., Charles, C. J., Lewis, L. K., Yandle, T. G., Cooper, G. J., Coy, D. H., Richards, A. M., & Nicholls, M. G. (1997). Beneficial hemodynamic and renal effects of adrenomedullin in an ovine model of heart failure. Circulation, 96(6), 1983-1990.
Pidgeon, G. B., Richards, A. M., Nicholls, M. G., Lewis, L. K., Yandle, T. G., Rademaker, M. T., Charles, C. J., … Lynn, K. L. (1997). Comparison of the effects of ouabain and brain natriuretic peptide in saline-loaded sheep. Clinical & Experimental Pharmacology & Physiology, 24(11), 807-813.
Lainchbury, J. G., Cooper, G. J. S., Coy, D. H., Jiang, N. Y., Lewis, L. K., Yandle, T. G., Richards, A. M., & Nicholls, M. G. (1997). Adrenomedullin: A hypotensive hormone in man. Clinical Science, 92(5), 467-472.
Lewis, L. K., Smith, M., Brennan, S. O., Yandle, T. G., Richards, A. M., & Nicholls, M. G. (1997). Degradation of human adrenomedullin (1-52) by plasma membrane enzymes and identification of metabolites. Peptides, 18(5), 733-739.
Conference Contribution - Published proceedings: Abstract
Rademaker, M. T., Charles, C. J., Lewis, L. K., Yandle, T. G., Richards, A. M., & Nicholls, M. G. (1997). Beneficial hemodynamic and renal effects of adrenomedullin in an ovine model of heart failure. The Journal of Heart Failure. 4(1), (pp. 74). [Abstract]
Pidgeon, G. B., Richards, A. M., Nicholls, M. G., Lewis, L. K., Yandle, T. G., Rademaker, M. T., Charles, C. J., … Lynn, K. (1997). Comparison of the effects of ouabain and brain natriuretic peptide in saline-loaded sheep. Proceedings of the 32nd Annual Meeting of Australian and New Zealand Society of Nephrology. 51, (pp. 1308). [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Lainchbury, J. G., Rademaker, M. T., Charles, C. J., Lewis, L. K., Yandle, T. G., Richards, A. M., & Nicholls, M. G. (1997). Adrenomedullin in heart failure. Verbal presentation at the 1st International Symposium on Adrenomedullin and PAMP, Osaka.
Rademaker, M. T., Charles, C. J., Lewis, L. K., Yandle, T. G., Richards, A. M., & Nicholls, M. G. (1997, June). Beneficial hemodynamic and renal effects of adrenomedullin in an ovine model of heart failure. Verbal presentation at the 8th European Society of Hypertension, Milan.
1996
Chapter in Book - Research
Nicholls, M. G., Pidgeon, G. B., Lewis, L. K., & Richards, A. M. (1996). Ouabain, adrenal glands and hypertension. In G. P. Vinson & D. C. Anderson (Eds.), Adrenal Glands, Vascular System and Hypertension. (pp. 115-121). Bradley Stoke, Bristol, U.K.: Journal of Endocrinology Limited.
Journal - Research Article
Lewis, L. K., Yandle, T. G., Lewis, J. G., Richards, A. M., Pidgeon, G. B., Kaaja, R. J., & Nicholls, M. G. (1996). Diabetes mellitus in older patients. Drugs & Aging, 6, 401-407.
Pidgeon, G. B., Lewis, L. K., Yandle, T. G., Richards, A. M., & Nicholls, M. G. (1996). Endogenous ouabain, sodium balance and blood pressure. Journal of Hypertension, 14, 169-171.
Pidgeon, G. B., Richards, A. M., Nicholls, M. G., Charles, C. J., Rademaker, M. T., Lynn, K. L., … Lewis, L. K., & Yandle, T. G. (1996). Chronic ouabain infusion does not cause hypertension in sheep. American Journal of Physiology: Endocrinology & Metabolism, 270(3), E386-E392.
Journal - Research Other
Richards, A. M., Nicholls, M. G., Lewis, L., & Lainchbury, J. G. (1996). Adrenomedullin [Editorial review]. Clinical Science, 91(1), 3-16. doi: 10.1042/cs0910003
1995
Journal - Research Article
Nicholls, M. G., Richards, A. M., Lewis, L. K., & Yandle, T. G. (1995). Ouabain: a new steroid hormone? Lancet, 346, 1381-1382.