Contact Details
- Phone
- +64 3 479 5919
- natalie.hughes@otago.ac.nz
University Links
- Position
- Professor, Deputy Dean and Associate Dean (Undergraduate Programmes)
- Qualifications
- PhD BSc(Stats) BPharm
- Research summary
- Clinical pharmacy; drug delivery
- Teaching
- Biopharmaceutics, drug delivery and clinical pharmaceutics to undergraduate and postgraduate students.
Research
Drug delivery in clinical pharmacy. This involves research spanning basic research of drug delivery systems, and their optimal use in patients.
Protein drug physical stability and analytical methods to study interactions between protein drugs and formulation excipients.
Additional details
Referee of articles in the pharmaceutical sciences.
Publications
Hughes, N. (2024, May). Molecules to medicines: Drug delivery for better health. University of Otago, Dunedin, New Zealand. [Inaugural Professorial Lecture]. Other Research Output
Wang, D., Hughes-Medlicott, N., Klingler, L., Wang, Y., Hung, N., Duffull, S., … Glue, P., … Jackson, C. (2024). A sensitive assay for unbound docetaxel using ultrafiltration plus HPLC-MS and its application to a clinical study. Pharmaceutics, 16, 602. doi: 10.3390/pharmaceutics16050602 Journal - Research Article
Wang, D., Jackson, C., Hung, N., Hung, T., Kwan, R., Chan, W.-K., … Hughes-Medlicott, N. J., Glue, P., & Duffull, S. (2024). Oral docetaxel plus encequidar: A pharmacokinetic model and evaluation against IV docetaxel. Journal of Pharmacokinetics & Pharmacodynamics. Advance online publication. doi: 10.1007/s10928-024-09913-y Journal - Research Article
Glue, P., Neehoff, S., Beaglehole, B., Shadli, S., McNaughton, N., & Hughes-Medlicott, N. J. (2024). Ketamine for treatment-resistant major depressive disorder: Double-blind active-controlled crossover study. Journal of Psychopharmacology, 38(2), 162-167. doi: 10.1177/02698811241227026 Journal - Research Article
Safii, S. H., Medlicott, N. J., Milne, T. J., & Duncan, W. J. (2023). Manuka honey as an adjunct to nonsurgical periodontal treatment: A pilot study. Annals of Dentistry, 30, 29-41. doi: 10.22452/adum.vol30no5 Journal - Research Article
2024
Journal - Research Article
Wang, D., Hughes-Medlicott, N., Klingler, L., Wang, Y., Hung, N., Duffull, S., … Glue, P., … Jackson, C. (2024). A sensitive assay for unbound docetaxel using ultrafiltration plus HPLC-MS and its application to a clinical study. Pharmaceutics, 16, 602. doi: 10.3390/pharmaceutics16050602
Wang, D., Jackson, C., Hung, N., Hung, T., Kwan, R., Chan, W.-K., … Hughes-Medlicott, N. J., Glue, P., & Duffull, S. (2024). Oral docetaxel plus encequidar: A pharmacokinetic model and evaluation against IV docetaxel. Journal of Pharmacokinetics & Pharmacodynamics. Advance online publication. doi: 10.1007/s10928-024-09913-y
Glue, P., Neehoff, S., Beaglehole, B., Shadli, S., McNaughton, N., & Hughes-Medlicott, N. J. (2024). Ketamine for treatment-resistant major depressive disorder: Double-blind active-controlled crossover study. Journal of Psychopharmacology, 38(2), 162-167. doi: 10.1177/02698811241227026
Other Research Output
Hughes, N. (2024, May). Molecules to medicines: Drug delivery for better health. University of Otago, Dunedin, New Zealand. [Inaugural Professorial Lecture].
2023
Journal - Research Article
Safii, S. H., Medlicott, N. J., Milne, T. J., & Duncan, W. J. (2023). Manuka honey as an adjunct to nonsurgical periodontal treatment: A pilot study. Annals of Dentistry, 30, 29-41. doi: 10.22452/adum.vol30no5
Ameratunga, R., Mears, E., Leung, E., Snell, R., Woon, S.-T., Kelton, W., Medlicott, N., … Steele, R., Rolleston, W., … Lehnert, K. (2023). Soluble wild-type ACE2 molecules inhibit newer SARS-CoV-2 variants and are a potential antiviral strategy to mitigate disease severity in COVID-19. Clinical & Experimental Immunology, 214, 289-295. doi: 10.1093/cei/uxad096
Broughton, L. C., Hughes-Medlicott, N., Zeng, J., & Smith, A. (2023). Perinatal psychotropic dispensing: A descriptive population-based study in New Zealand. Asia-Pacific Psychiatry. Advance online publication. doi: 10.1111/appy.12539
Besley, N., Browne, P., Park, M., Pesheva, P., Wong, K., Medlicott, N. J., & McDowell, A. (2023). Pharmacists in zoos? A qualitative study investigating the potential for pharmacist involvement in wildlife healthcare in Aotearoa New Zealand. Journal of the American Pharmacists Association, 63(3), 825-831. doi: 10.1016/j.japh.2023.01.008
Kremer, L. J., Medlicott, N., Sime, M. J., Broadbent, R., Edmonds, L., Berry, M. J., Austin, N. C., … Reith, D. M. (2023). Low dose or very low dose phenylephrine and cyclopentolate microdrops for retinopathy of prematurity eye examinations (The Little Eye Drop Study): A randomised controlled non-inferiority trial. Archives of Disease in Childhood: Fetal & Neonatal Edition, 108, F380-F386. doi: 10.1136/archdischild-2022-324929
Journal - Research Other
Woods, S. J., Hughes-Medlicott, N. J., & McDowell, A. (2023). Pharmacokinetics in penguins compared to other avian species: A review of enrofloxacin and voriconazole. Molecular Pharmaceutics. Advance online publication. doi: 10.1021/acs.molpharmaceut.3c00520
Conference Contribution - Published proceedings: Abstract
Kremer, L. J., Edmonds, L. K., Sime, M. J., Broadbent, R. S., Medlicott, N. J., Berry, M. J., Austin, N. C., … Reith, D. M. (2023). The Little Eye Drop Study: Are very low dose mydriatics in a microdrop effective and safe for ROP eye examinations? Journal of Paediatrics & Child Health, 59(Suppl. 1), (pp. 89). doi: 10.1111/jpc.16357
2022
Journal - Research Article
Kremer, L., Reith, D., Medlicott, N. J., Sime, M. J., Edmonds, L., & Broadbent, R. (2022). A survey of neonatal nurses on mydriatic regimens used in neonatal retinopathy of prematurity eye examinations. American Journal of Perinatology, 39(16), 1779-1785. doi: 10.1055/s-0041-1726316
Conference Contribution - Verbal presentation and other Conference outputs
Broughton, L., Medlicott, N., Zeng, J., & Smith, A. (2022, November). Perinatal psychotropic dispensing: A description population-based study in New Zealand. Verbal presentation at the School of Pharmacy Research Day, Dunedin, New Zealand.
2021
Journal - Research Article
Porter, G. C., Safii, S. H., Medlicott, N. J., Duncan, W. J., Tompkins, G. R., & Coates, D. E. (2021). Formulation of a semisolid emulsion containing Leptospermum scoparium essential oil and evaluation of in vitro antimicrobial and antibiofilm efficacy. Planta Medica, 87, 253-266. doi: 10.1055/a-1330-8765
Kremer, L. J., Broadbent, R., Medlicott, N., Sime, M. J., McCaffrey, F., & Reith, D. M. (2021). Randomised controlled pilot trial comparing low dose and very low- dose microdrop administration of phenylephrine and cyclopentolate for retinopathy of prematurity eye examinations in neonates. Archives of Disease in Childhood, 106, 603-608. doi: 10.1136/archdischild-2019-318733
Journal - Research Other
Kremer, L., Reith, D., Medlicott, N. J., Sime, M. J., Edmonds, L., & Broadbent, R. (2021). Microdrop administration of mydriatics may reduce the risk of NEC. Pediatrics International, 63(6), 741. doi: 10.1111/ped.14620
Ameratunga, R., Woon, S.-T., Steele, R., Snell, R., Medlicott, N., Mears, E., … Das, S., … Quiñones‑Mateu, M. E. (2021). The nose and the stomach play a critical role in the NZACE2-Pātari* (modified ACE2) drug treatment project of SARS-CoV-2 infection. Expert Review of Clinical Immunology, 17(6), 553-560. doi: 10.1080/1744666x.2021.1912596
Broughton, L. C., Medlicott, N. J., & Smith, A. J. (2021). Effectiveness of patient decision aids in women considering psychotropic medication use during pregnancy: A literature review. Archives of Women's Mental Health, 24, 569-578. doi: 10.1007/s00737-021-01118-3
Glue, P., Russell, B., & Medlicott, N. J. (2021). Influence of formulation and route of administration on ketamine's safety and tolerability: Systematic review. European Journal of Clinical Pharmacology, 77, 671-676. doi: 10.1007/s00228-020-03047-z
2020
Journal - Research Article
Simpson, B. H., Reith, D. M., Medlicott, N. J., & Smith, A. J. (2020). Monitoring the use of dabigatran etexilate for stroke prevention: Compliance with renal function guidelines. Journal of Primary Health Care, 12(4), 327-334. doi: 10.1071/HC19115
Porter, G. C., Schwass, D. R., Tompkins, G. R., Bobbala, S. K. R., Medlicott, N. J., & Meledandri, C. J. (2020). AgNP/Alginate Nanocomposite hydrogel for antimicrobial and antibiofilm applications. Carbohydrate Polymers, 251, 117017. doi: 10.1016/j.carbpol.2020.117017
Glue, P., Medlicott, N. J., Neehoff, S., Surman, P., Lam, F., Hung, N., & Hung, C.-T. (2020). Safety and efficacy of extended release ketamine tablets in patients with treatment-resistant depression and anxiety: Open label pilot study. Therapeutic Advances in Psychopharmacology, 10, 1-6. doi: 10.1177/2045125320922474
Glue, P., Medlicott, N. J., Surman, P., Lam, F., Hung, N., & Hung, C. T. (2020). Ascending-dose study of controlled-release ketamine tablets in healthy volunteers: Pharmacokinetics, pharmacodynamics, safety, and tolerability. Journal of Clinical Pharmacology, 60(6), 751-757. doi: 10.1002/jcph.1573
Glue, P., Neehoff, S., Sabadel, A., Broughton, L., Le Nedelec, M., Shadli, S., McNaughton, N., & Medlicott, N. J. (2020). Effects of ketamine in patients with treatment-refractory generalized anxiety and social anxiety disorders: Exploratory double-blind psychoactive-controlled replication study. Journal of Psychopharmacology, 34(3), 267-272. doi: 10.1177/0269881119874457
Journal - Research Other
Ameratunga, R., Lehnert, K., Leung, E., Comoletti, D., Snell, R., Woon, S.-T., … Medlicott, N., Das, S., … Quiñones‑Mateu, M., … Jordan, A. (2020). Inhaled modified angiotensin converting enzyme 2 (ACE2) as a decoy to mitigate SARS-CoV-2 infection. New Zealand Medical Journal, 133(1515), 112-118. Retrieved from https://www.nzma.org.nz/journal
2019
Chapter in Book - Research
Hanning, S. M., Medlicott, N. J., & Oliphant, E. A. (2019). Clinical pharmacy considerations in special population: Pediatrics. In Z. U.-D. Babar (Ed.), Encyclopedia of pharmacy practice and clinical pharmacy (Vol. 3: Part A). (1st ed.) (pp. 815-830). Amsterdam, The Netherlands: Elsevier. doi: 10.1016/B978-0-12-812735-3.00574-4
Journal - Research Article
Simpson, B. H., Reith, D. M., Medlicott, N. J., & Smith, A. J. (2019). Exposure response supports therapeutic drug monitoring for dabigatran etexilate in patients with atrial fibrillation. TH Open, 3(3), e210-e215. doi: 10.1055/s-0039-1693486
Ritchie, D., Broadbent, R., Medlicott, N., & Reith, D. M. (2019). In vitro validation of a method for neonatal urine collection and analysis. BMJ Paediatrics Open, 3(1), e000482. doi: 10.1136/bmjpo-2019-000482
Kremer, L. J., Reith, D. M., Medlicott, N., & Broadbent, R. (2019). Systematic review of mydriatics used for screening of retinopathy in premature infants. BMJ Paediatrics Open, 3(1), 3000448. doi: 10.1136/bmjpo-2019-000448
Abdul Aziz, Y. H., Al-Sallami, H. S., Wiltshire, E., Rayns, J., Willis, J., McClintock, J., Medlicott, N., Wheeler, B. J., the Paediatric Society of New Zealand Diabetes Clinical Network. (2019). Insulin pump initiation and education for children and adolescents: A qualitative study of current practice in New Zealand. Journal of Diabetes & Metabolic Disorders, 18, 59-64. doi: 10.1007/s40200-019-00390-6
Thew, J., Burrage, P., Medlicott, N., & Mallet, D. (2019). Modelling optimal delivery of bFGF to chronic wounds using ODEs. Journal of Theoretical Biology, 465, 109-116. doi: 10.1016/j.jtbi.2018.12.028
Dowd, L. A., Wheeler, B. J., Al-Sallami, H. S., Broadbent, R. S., Edmonds, L. K., & Medlicott, N. J. (2019). Paracetamol treatment for patent ductus arteriosus: Practice and attitudes in Australia and New Zealand. Journal of Maternal-Fetal & Neonatal Medicine, 32(18), 3039-3044. doi: 10.1080/14767058.2018.1456520
Conference Contribution - Published proceedings: Abstract
Kremer, L., Reith, D., Medlicott, N., & Broadbent, R. (2019). Very low doses of phenylephrine and cyclopentolate eye drops sufficiently dilate the pupil for ROP eye examinations. Journal of Paediatrics & Child Health, 55(Suppl. 1), (pp. 28). doi: 10.1111/jpc.14406
Shadli, S. M., Glue, P., McNaughton, N., & Medlicott, N. (2019). Therapeutic effects of ketamine on treatment refractory generalized anxiety and social anxiety disorders are unrelated to plasma levels: A double blind active controlled study. Proceedings of the Society for Neuroscience Annual Meeting. 595.07/V21. SfN. Retrieved from https://www.sfn.org
Salis, G., Medlicott, N., & Reith, D. (2019). Modelling of delivery kinetics of gentamicin administered through umbilical long lines. Proceedings of the 20th Annual Population Approach Group in Australia and New Zealand Meeting (PAGANZ). (pp. 18-19). Retrieved from https://www.paganz.org/auckland-2019
Simpson, B., Reith, D., Medlicott, N., & Smith, A. (2019). Estimated exposure to dabigatran etexilate influences efficacy and toxicity. European Journal of Clinical Pharmacology, 75(Suppl. 1), (pp. S90). doi: 10.1007/s00228-019-02685-2
Simpson, B., Reith, D., Medlicott, N., & Smith, A. (2019). Poor adherence to renal function testing for dabigatran. European Journal of Clinical Pharmacology, 75(Suppl. 1), (pp. S28-S29). doi: 10.1007/s00228-019-02685-2
Intellectual Property
Glue, P. W., Medlicott, N. J., & Surman, P. W. (2019). Extended release pharmaceutical formulation. (10,441,544). United States.
2018
Journal - Research Article
Simpson, B. H., Reith, D., Medlicott, N. J., & Smith, A. (2018). Deprivation and inequalities lead to worse outcomes with dabigatran etexilate. Journal of Primary Health Care, 10(4), 303-311. doi: 10.1071/HC17081
Simpson, B. H., Reith, D. M., Medlicott, N. J., & Smith, A. J. (2018). Choice of renal function estimator influences adverse outcomes with dabigatran etexilate in patients with atrial fibrillation. TH Open, 2(04), e420-e427. doi: 10.1055/s-0038-1676356. ISSN 2512-9465
Muller, M., Wheeler, B. J., Blackwell, M., Colas, M., Reith, D. M., Medlicott, N. J., & Al-Sallami, H. S. (2018). The influence of patient variables on insulin total daily dose in paediatric inpatients with new onset type 1 diabetes mellitus. Journal of Diabetes & Metabolic Disorders, 17, 159-163. doi: 10.1007/s40200-018-0355-5
Le Nedelec, M., Glue, P., Winter, H., Goulton, C., & Medlicott, N. J. (2018). The effect of route of administration on the enantioselective pharmacokinetics of ketamine and norketamine in rats. Journal of Psychopharmacology, 32(10), 1127-1132. doi: 10.1177/0269881118780013
Smith, A. J., Scahill, S. L., Harrison, J., Carroll, T., & Medlicott, N. J. (2018). Service provision in the wake of a new funding model for community pharmacy. BMC Health Services Research, 18, 307. doi: 10.1186/s12913-018-3120-z
Glue, P., Neehoff, S. M., Medlicott, N. J., Gray, A., Kibby, G., & McNaughton, N. (2018). Safety and efficacy of maintenance ketamine treatment in patients with treatment-refractory generalised anxiety and social anxiety disorders. Journal of Psychopharmacology, 32(6), 663-667. doi: 10.1177/0269881118762073
Le Nedelec, M., Glue, P., Winter, H., Goulton, C., Broughton, L., & Medlicott, N. (2018). Acute low-dose ketamine produces a rapid and robust increase in plasma BDNF without altering brain BDNF concentrations. Drug Delivery & Translational Research, 8(3), 780-786. doi: 10.1007/s13346-017-0476-2
Zeeshan, F., Tabbassum, M., Jorgensen, L., & Medlicott, N. J. (2018). Attenuated total reflection Fourier transform infrared (ATR FT-IR) spectroscopy as an analytical method to investigate the secondary structure of a model protein embedded in solid lipid matrices. Applied Spectroscopy, 72(2), 268-279. doi: 10.1177/0003702817739908
Conference Contribution - Published proceedings: Abstract
Gandhi, P., Wheeler, B. J., Edmonds, L., Medlicott, N., Broadbent, R., & Al-Sallami, H. S. (2018). How is neonatal hyperglycaemia treated in NICUs across Australia and New Zealand? Journal of Paediatrics & Child Health, 54(Suppl. 1), (pp. 75-76). doi: 10.1111/jpc.13881
2017
Journal - Research Article
Salis, E. R., Reith, D. M., Wheeler, B. J., Broadbent, R. S., & Medlicott, N. J. (2017). Hyperglycaemic preterm neonates exhibit insulin resistance and low insulin production. BMJ Paediatrics Open, 1(1), e000160. doi: 10.1136/ bmjpo-2017-000160
Apperley, O., Medlicott, N., Rich, A., Hanning, S., & Huckabee, M. L. (2017). A clinical trial of a novel emulsion for potential use as a saliva substitute in patients with radiation induced xerostomia. Journal of Oral Rehabilitation, 44(11), 889-895. doi: 10.1111/joor.12545
Glue, P., Medlicott, N. J., Harland, S., Neehoff, S., Anderson-Fahey, B., Le Nedelec, M., Gray, A., & McNaughton, N. (2017). Ketamine's dose-related effects on anxiety symptoms in patients with treatment refractory anxiety disorders. Journal of Psychopharmacology, 31(10), 1302-1305. doi: 10.1177/0269881117705089
Salis, E. R., Reith, D. M., Wheeler, B. J., Broadbent, R. S., & Medlicott, N. J. (2017). Insulin resistance, glucagon-like peptide-1 and factors influencing glucose homeostasis in neonates. Archives of Disease in Childhood: Fetal & Neonatal Edition, 102(2), F162-F166. doi: 10.1136/archdischild-2015-309174
Conference Contribution - Published proceedings: Abstract
Symon, V., Heydon, S., & Medlicott, N. (2017). Finding your respondents: Snowball sampling in online survey-based research: Advantages, limitiations and practical considerations. In A. Finigan, M. Taumoepeau, R. Richards & M. Schaaf (Eds.), Proceedings of the Pacific Postgraduate Symposium: Pacific Voices XIV. (pp. 29). Dunedin, New Zealand: Pacific Islands Centre, University of Otago. Retrieved from https://www.otago.ac.nz/pacific-at-otago/research/index.html
Gandhi, P., Wheeler, B., Edmonds, L., Medlicott, N., Broadbent, R., Reith, D., & Al-Sallami, H. (2017). Neonatal hyperglycaemia management: Current practice in Australia and New Zealand. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 27). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html
Dowd, L., Wheeler, B., Al-Sallami, H., Broadbent, R., Edmonds, L., Reith, D., & Medlicott, N. (2017). Paracetamol treatment for patent ductus arteriosus: Current clinical practices and attitudes. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 19-20). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html
Simpson, B., Reith, D., Medlicott, N., & Smith, A. (2017). Utilisation of New Zealand primary care electronic data to guide clinical decision support system design: A retrospective cohort for dabigatran. Clinical Therapeutics, 39(8, Suppl.), (pp. e7). doi: 10.1016/j.clinthera.2017.05.024
Simpson, B., Reith, D., Medlicott, N., & Smith, A. (2017). Choice of renal function estimator may affect adverse outcomes with dabigatran. Clinical Therapeutics, 39(8, Suppl.), (pp. e7). doi: 10.1016/j.clinthera.2017.05.023
Reith, D., Simpson, B., Medlicott, N., & Smith, A. (2017). Dabigatran exposure and outcomes: A PK/PD/PV study. Clinical Therapeutics, 39(8, Suppl.), (pp. e8). doi: 10.1016/j.clinthera.2017.05.026
Conference Contribution - Verbal presentation and other Conference outputs
Reith, D., Simpson, B., Medlicott, N., & Smith, A. (2017, September). Prediction of drug exposure in pharmacoepidemiology studies: Dabigatran as a case study. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand.
2016
Journal - Research Article
Hanning, S. M., & Medlicott, N. J. (2016). Oil-based compositions as saliva substitutes: A pilot study to investigate in-mouth retention. International Journal of Pharmaceutics, 501, 265-270. doi: 10.1016/j.ijpharm.2016.01.058
Salis, E. R., Reith, D. M., Broadbent, R. S., & Medlicott, N. J. (2016). Haematocrit influences insulin concentration measurements in dried blood spots. Journal of Maternal-Fetal & Neonatal Medicine, 29(19), 3208-3211. doi: 10.3109/14767058.2015.1119116
Linakis, M. W., Roberts, J. K., Lala, A. C., Spigarelli, M. G., Medlicott, N. J., Reith, D. M., … Sherwin, C. M. T. (2016). Challenges associated with route of administration in neonatal drug delivery. Clinical Pharmacokinetics, 55(2), 185-196. doi: 10.1007/s40262-015-0313-z
Salis, E. R., Soelbeck, M. K., Reith, D. M., Wheeler, B. J., Broadbent, R. S., & Medlicott, N. J. (2016). Effect of gestational age and blood glucose on C-peptide excretion rate and clearance in neonates. Journal of Paediatrics & Child Health, 52(1), 60-66. doi: 10.1111/jpc.12977
Conference Contribution - Published proceedings: Abstract
Symon, V., Heydon, S. J., Medlicott, N., & Fleming, J. S. (2016). Science in crime fiction: Accuracy and the reader experience. In A. Finigan, M. Taumoepeau, I. Iati, P. Vakaoti & R. Richards (Eds.), Proceedings of the Pacific Postgraduate Symposium: Pacific Voices XIII. (pp. 19). Dunedin, New Zealand: Pacific Islands Centre, University of Otago. [Abstract]
Abdul Aziz, Y., Al-Sallami, H., Wiltshire, E., Willis, J., Rayns, J., McClintock, J., Medlicott, N., & Wheeler, B. (2016). Insulin pump initiation and education: Current paediatric practice in Australia and New Zealand. Proceedings of the Australasian Paediatric Endocrine Group Conference. Retrieved from https://willorganise.eventsair.com/QuickEventWebsitePortal/2016-apeg-conference/website
Safii, S., Duncan, W., Tompkins, G., & Medlicott, N. (2016). Effect of medical-grade manuka honey on dental plaque-associated bacteria and hydroxyapatite beads in vitro. Proceedings of the Sir John Walsh Research Institute Research Symposium. (pp. 13-14). Retrieved from http://www.otago.ac.nz/sjwri/news/otago621026
Simpson, B., Reith, D., Medlicott, N., Smith, A., & Tilyard, M. (2016). New Zealand formulary for children: A case study of national paediatric formulary development. Archives of Disease in Childhood, 101, e1. doi: 10.1136/archdischild-2015-310148.25
2015
Journal - Research Article
Symon, V., Heydon, S., Medlicott, N. J., Kieser, J., & Fleming, J. S. (2015). Before CSI: Making the case for a novel portrayal of forensic science. International Journal of Science in Society, 6, 7-15.
Kanjanakawinkul, W., Medlicott, N. J., Rades, T., Puttipipatkhachorn, S., & Pongjanyakul, T. (2015). Lysozyme–magnesium aluminum silicate microparticles: Molecular interaction, bioactivity and release studies. International Journal of Biological Macromolecules, 80, 651-658. doi: 10.1016/j.ijbiomac.2015.07.033
Madsen, C. G., Skov, A., Baldursdottir, S., Rades, T., Jorgensen, L., & Medlicott, N. J. (2015). Simple measurements for prediction of drug release from polymer matrices: Solubility parameters and intrinsic viscosity. European Journal of Pharmaceutics & Biopharmaceutics, 92, 1-7. doi: 10.1016/j.ejpb.2015.02.001
Al-Sallami, H. S., & Medlicott, N. J. (2015). Investigation of an anti-activated factor X (anti-Xa) assay for the quantification of enoxaparin in human plasma. Journal of Pharmacy & Pharmacology, 67(2), 209-214. doi: 10.1111/jphp.12333
Owens, K. H., Medlicott, N. J., Zacharias, M., Whyte, I. M., Buckley, N. A., & Reith, D. M. (2015). Population pharmacokinetic-pharmacodynamic modelling to describe the effects of paracetamol and N-acetylcysteine on the international normalized ratio. Clinical & Experimental Pharmacology & Physiology, 42(1), 102-108. doi: 10.1111/1440-1681.12327
Journal - Research Other
Lala, A. C., Broadbent, R. S., Medlicott, N. J., Sherwin, C. M. T., & Reith, D. M. (2015). Illustrative neonatal cases regarding drug delivery issues. Journal of Paediatrics & Child Health, 51, 478-481. doi: 10.1111/jpc.12764
Conference Contribution - Published proceedings: Abstract
Symon, V., Heydon, S., Medlicott, N. J., Kieser, J., & Fleming, J. S. (2015). Before CSI: Making the case for a novel portrayal of forensic science. In C. Matthewson, M. Taumoepeau, I. Iati, M. Inder, C. Pau & R. Richards (Eds.), Proceedings of the Pacific Postgraduate Symposium: Pacific Voices XII. (pp. 47). Dunedin, New Zealand: Pacific Islands Centre, University of Otago. [Abstract]
Salis, E. R., Soelbeck, M. K., Reith, D. M., Wheeler, B. J., Broadbent, R. S., & Medlicott, N. J. (2015). C-peptide clearance: Potential marker of endogenous insulin secretion for Pkpd studies of insulin in neonates. Clinical Therapeutics, 37(8, Suppl.), (pp. e59). doi: 10.1016/j.clinthera.2015.05.176
Conference Contribution - Poster Presentation (not in published proceedings)
Lala, A., Medlicott, N., Broadbent, R., McCaffrey, F., & Reith, D. (2015, June). Gentamicin pharmacokinetic variability is influenced by choice of administration route. Poster session presented at the 15th Biennial European Society for Developmental, Perinatal and Paediatric Pharmacology (ESDPPP) Congress, Belgrade, Serbia.
Medlicott, N., Thomas, L., Broadbent, R., & Reith, D. (2015, June). Slow infusions of gentamicin are associated with high variability in peak gentamicin concentrations in low gestation age (GA) neonates. Poster session presented at the 15th Biennial European Society for Developmental, Perinatal and Paediatric Pharmacology (ESDPPP) Congress, Belgrade, Serbia.
Salis, E. R., Reith, D. M., Broadbent, R. S., Wheeler, B. J., & Medlicott, N. J. (2015, June). Extremely premature neonates exhibit insulin resistance. Poster session presented at the 15th Biennial European Society for Developmental, Perinatal and Paediatric Pharmacology (ESDPPP) Congress, Belgrade, Serbia.
Simpson, B., Reith, D., Medlicott, N., Smith, A., & Tilyard, M. (2015, June). New Zealand formulary for children: A case study of national paediatric formulary development. Poster session presented at the 15th Biennial European Society for Developmental, Perinatal and Paediatric Pharmacology (ESDPPP) Congress, Belgrade, Serbia.
Conference Contribution - Verbal presentation and other Conference outputs
Lala, A., Medlicott, N. J., Broadbent, R. S., McCaffrey, F. T., & Reith, D. M. (2015, November). Variability in neonatal gentamicin administration influencing drug delivery kinetics. Verbal presentation at the Paediatric Society of New Zealand 67th Annual Scientific Meeting, Wellington, New Zealand.
Salis, E. R., Reith, D. M., Broadbent, R. S., Wheeler, B. J., & Medlicott, N. J. (2015, September). Extremely premature neonates exhibit insulin resistance. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand.
Lala, A., Reith, D., Broadbent, R., & Medlicott, N. (2015, June). Effect of flush volume on gentamicin delivery through umbilical venous catheters. Verbal presentation at the 15th Biennial European Society for Developmental, Perinatal and Paediatric Pharmacology (ESDPPP) Congress, Belgrade, Serbia.
Zare, D., Medlicott, N., & McGrath, K. M. (2015, February). Surface visco-elasticity of milk protein. Verbal presentation at the Seventh International Conference on Advanced Materials & Nanotechnology (AMN-7), Nelson, New Zealand.
2014
Journal - Research Article
Owens, K. H., Murphy, P. G. M., Medlicott, N. J., Kennedy, J., Zacharias, M., Curran, N., Sreebhavan, S., Thompson-Fawcett, M., & Reith, D. M. (2014). Population pharmacokinetics of intravenous acetaminophen and its metabolites in major surgical patients. Journal of Pharmacokinetics & Pharmacodynamics, 41(3), 211-221. doi: 10.1007/s10928-014-9358-0
Sherwin, C. M. T., Medlicott, N. J., Reith, D. M., & Broadbent, R. S. (2014). Intravenous drug delivery in neonates: Lessons learnt. Archives of Disease in Childhood, 99, 590-594. doi: 10.1136/archdischild-2013-304887
McDowell, A., Fothergill, J. A., Khan, A., & Medlicott, N. J. (2014). A cyclodextrin formulation to improve use of the anesthetic tribromoethanol (Avertin®). Journal of Pharmacy & BioAllied Sciences, 6(1), 16-21. doi: 10.4103/0975-7406.124303
Hanning, S. M., Kieser, J. A., Ferguson, M. M., Reid, M., & Medlicott, N. J. (2014). The use of lithium as a marker for the retention of liquids in the oral cavity after rinsing. Clinical Oral Investigations, 18(5), 1533-1537. doi: 10.1007/s00784-013-1141-x
Conference Contribution - Published proceedings: Abstract
Hanning, S., Yu, T., Jones, D., Andrews, G., Kieser, J., & Medlicott, N. (2014). Characterisation of emulsions as potential saliva substitutes. New Zealand Dental Journal, 110(1), (pp. 27). [Abstract]
Apperley, O., Kieser, J., Huckabee, M.-L., Medlicott, N., & MacFadyen, E. (2014). Management of xerostomia following radiotherapy: A randomised, double blind, cross-over study of a novel emulsion for use as a saliva substitute. New Zealand Dental Journal, 110(1), (pp. 24). [Abstract]
Conference Contribution - Poster Presentation (not in published proceedings)
Zeeshan, F., Medlicott, N., & Jörgensen, L. (2014, November). Conformational stability of proteins in solid lipid matrices: Effect of protein inherent thermal stability. Poster session presented at the Devices for Diagnostics and Drug Delivery (D4) Conference, Dunedin, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Robinson, A., Ussher, J., & Medlicott, N. (2014, November). Novel methods for the rapid identification and susceptibility testing of blood culture isolates. Invited presentation at the Devices for Diagnostics and Drug Delivery (D4) Conference, Dunedin, New Zealand.
2013
Chapter in Book - Research
Braund, R., & Medlicott, N. J. (2013). Biomaterials as platforms for topical administration of therapeutic agents in cutaneous wound healing. In S. Dumitriu & V. Popa (Eds.), Polymeric biomaterials: Structure and function. (pp. 837-850). Boca Raton, FL: CRC Press.
Journal - Research Article
Hanning, S. M., Yu, T., Jones, D. S., Andrews, G. P., Kieser, J. A., & Medlicott, N. J. (2013). Lecithin-based emulsions for potential use as saliva substitutes in patients with xerostomia: Viscoelastic properties. International Journal of Pharmaceutics, 456(2), 560-568. doi: 10.1016/j.ijpharm.2013.08.009
Medlicott, N. J., Reith, D. M., McCaffrey, F., Krittaphol, W., & Broadbent, R. S. (2013). Delayed delivery of intravenous gentamicin in neonates: Impact of infusion variables. Journal of Pharmacy & Pharmacology, 65(3), 370-378. doi: 10.1111/jphp.12000
Conference Contribution - Published proceedings: Abstract
Medlicott, N. J. (2013). Protein instability on interfaces: Implications for dosage form design. Proceedings of the Australasian Pharmaceutical Science Association (APSA) Conference. Retrieved from http://apsa-online.org/home.html
Salis, E., Reith, D., Wheeler, B., Broadbent, R., & Medlicott, N. J. (2013). Is C-peptide clearance and urinary excretion rate affected by gestational age or blood glucose concentration in neonates? Proceedings of the Paediatric Society of New Zealand 65th Annual Scientific Meeting. (pp. 94). Retrieved from http://www.psnz2013.co.nz/
Salis, E. R., Reith, D. M., Broadbent, R. S., Wheeler, B. J., & Medlicott, N. J. (2013). The effect of gestational age on the insulin to c-peptide ratio in neonates. Therapeutic Drug Monitoring, 35(5), (pp. 692). doi: 10.1097/FTD.0b013e3182a8ef2b
Hanning, S. M., Yu, T., Kieser, J. A., & Medlicott, N. J. (2013). Characterization of an oily formulation for the management of xerostomia. Journal of Dental Research, 92(Spec Iss A), 930. Retrieved from http://www.dentalresearch.org
Hanning, S. M., Medlicott, N. J., Kieser, J. A., & Ferguson, M. M. (2013). Retention of liquids in the oral cavity after rinsing. Journal of Dental Research, 92(Spec Iss A), 2603. Retrieved from http://www.dentalresearch.org
Conference Contribution - Poster Presentation (not in published proceedings)
Salis, E. R., Soelbeck, M. K., Reith, D. M., Broadbent, R. S., & Medlicott, N. J. (2013, August). Can a chemiluminescent immunoassay be used to measure urinary C-peptide in neonates? Poster session presented at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Hanning, S., Yu, T., Jones, D., Andrews, G., Kieser, J., & Medlicott, N. (2013, October). Characterisation of emulsions as potential saliva substitutes. Verbal presentation at the 9th Biomouth Conference, Dunedin, New Zealand.
Apperley, O., Kieser, J., Huckabee, M.-L., Medlicott, N., & MacFadyen, E. (2013, October). Management of xerostomia following radiotherapy: A randomised, double blind, cross-over study of novel emulsion for use as a saliva substitute. Verbal presentation at the 9th Biomouth Conference, Dunedin, New Zealand.
Owens, K. H., Medlicott, N. J., Whyte, I. M., Buckley, N. A., & Reith, D. M. (2013, August). Development of a population PKPD model to describe the effect of paracetamol on the International Normalised Ratio (INR). Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand.
2012
Chapter in Book - Research
McDowell, A., & Medlicott, N. J. (2012). Anatomy and physiology of the injection site: Implications for extended release parenteral systems. In J. C. Wright & D. J. Burgess (Eds.), Long acting injections and implants. (pp. 57-71). New York: Springer. doi: 10.1007/978-1-4614-0554-2_4
Journal - Research Article
Owens, K. H., Medlicott, N. J., Zacharias, M., Chary, S., Thompson-Fawcett, M., & Reith, D. M. (2012). The pharmacokinetic profile of intravenous paracetamol in adult patients undergoing major abdominal surgery. Therapeutic Drug Monitoring, 34(6), 713-721. doi: 10.1097/FTD.0b013e31826a70ea
Hanning, S., Motoi, L., Medlicott, N., & Swindells, S. (2012). A device for the collection of submandibular saliva. New Zealand Dental Journal, 108(1), 4-8.
Conference Contribution - Published proceedings: Abstract
Guzman, P., Medlicott, N. J., Rades, T., Jorgensen, L., & Baldursdottir, S. G. (2012). Characterization of protein (BSA) adsorption to the water-oil interface. Proceedings of the 243rd American Chemical Society (ACS) National Meeting & Exposition. Retrieved from http://www.acs.org/content/acs/en/meetings/nationalmeetings/programarchive.html
Salis, E. R., Reith, D. M., & Medlicott, N. J. (2012). The effect of haematocrit on insulin levels from dried blood spots for use in clinical studies. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) and the Australasian Pharmaceutical Science Association (APSA) Joint Conference: Medication Safety. (pp. 199). Retrieved from http://www.ascept-apsa.com/
Thomas, L. A., Medlicott, N. J., Broadbent, R., & Reith, D. M. (2012). An evaluation of a change in dosing regimen of gentamicin in neonates. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) and the Australasian Pharmaceutical Science Association (APSA) Joint Conference: Medication Safety. (pp. 146). Retrieved from http://www.ascept-apsa.com/
Owens, K. H., Medlicott, N. J., Whyte, I. M., Buckley, N. A., & Reith, D. M. (2012). Development of a population PKPD model to describe the effect of paracetamol on the International Normalised Ratio (INR). Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) and the Australasian Pharmaceutical Science Association (APSA) Joint Conference: Medication Safety. (pp. 142). Retrieved from http://www.ascept-apsa.com/
Zeeshan, F., Jorgensen, L., & Medlicott, N. J. (2012). Conformational stability of various proteins in solid lipid matrices prepared by melting and cooling. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) and the Australasian Pharmaceutical Science Association (APSA) Joint Conference: Medication Safety. (pp. 48). Retrieved from http://www.ascept-apsa.com/
Hanning, S. M., Yu, T., Jones, D. S., Kieser, J. A., & Medlicott, N. J. (2012). Characterisation of emulsions as potential saliva substitutes in xerostomia. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) and the Australasian Pharmaceutical Science Association (APSA) Joint Conference: Medication Safety. (pp. 48). Retrieved from http://www.ascept-apsa.com/
Hanning, S., Medlicott, N., Kieser, J., Jones, D. S., & Yu, T. (2012). The rheological properties of an emulsion for potential use as a saliva substitute in patients with xerstomia. Proceedings of the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives. Retrieved from http://bioactives.otago.ac.nz/
Madsen, C. G., Skov, A., Jørgensen, L., Baldursdottir, S., & Medlicott, N. (2012). Effect of blended solvents on polymer film formation: Tracking of low dose protein release, correlated to the degree of polymer unfolding. Proceedings of the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives. Retrieved from http://bioactives.otago.ac.nz/
Skov, A., Madsen, C. G., Baldursdottir, S., Jørgensen, L., & Medlicott, N. (2012). Effect of blended solvents on polymer film formation: Correlation between the Hildebrand solubility parameters and the intrinsic viscosity of polymer solutions. Proceedings of the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives. Retrieved from http://bioactives.otago.ac.nz/
Medlicott, N. (2012). Use of proteins as therapeutic agents. Proceedings of the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives. Retrieved from http://bioactives.otago.ac.nz/
Kanjanakawinkul, W., Puttipipatkhachorn, S., Medlicott, N., Rades, T., & Pongjanyakul, T. (2012). Characterisation of nicotine-magnesium aluminum silicate microparticles for mucosal delivery. Proceedings of the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives. Retrieved from http://bioactives.otago.ac.nz/
Zeeshan, F., Medlicott, N., & Jorgensen, L. (2012). Investigation of protein structure in lipid matrices prepared by physical mixing followed by melting and cooling. Proceedings of the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives. Retrieved from http://bioactives.otago.ac.nz/
Curran, N., Thompson-Fawcett, M., Zacharias, M., Reith, D., Young, S., & Medlicott, N. (2012). The effect of major abdominal surgery on cytokine production. ANZ Journal of Surgery, 82(Suppl. 1), (pp. 76). doi: 10.1111/j.1445-2197.2012.06056.x
Owens, K., Murphy, P., Medlicott, N., Kennedy, J., Zacharias, M., Curran, N., Chary, S., Thompson-Fawcett, M., & Reith, D. (2012). The pharmacokinetic profile of intravenous paracetamol in adult patients undergoing major surgery: A population analysis. Proceedings of the Twenty-First Annual Meeting of the Population Approach Group in Europe (PAGE). 2394. Retrieved from http://www.page-meeting.org/default.asp?abstract=2394
Owens, K., Medlicott, N., Murphy, P., Kennedy, J., Zacharias, M., Chary, S., Curran, N., Thompson-Fawcett, M., & Reith, D. (2012). The pharmacokinetic profile of intravenous paracetamol in adult patients undergoing major abdominal surgery: A population analysis. Proceedings of the 14th Annual Population Approach Group in Australia and New Zealand Meeting (PAGANZ). Retrieved from http://www.paganz.org/conference/melbourne-2012-14th-annual-scientific-meeting
Conference Contribution - Poster Presentation (not in published proceedings)
Hanning, S., Yu, T., Medlicott, N., Kieser, J., & Jones, D. (2012, September). The rheology of a formulation for the treatment of xerostomia. Poster session presented at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand.
Owens, K., Medlicott, N., Zacharias, M., Curran, N., Chary, S., Thompson-Fawcett, M., & Reith, D. (2012, September). The pharmacokinetic profile of intravenous paracetamol in adult patients undergoing major abdominal surgery. Poster session presented at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand.
Owens, K., Medlicott, N., Whyte, I., Buckley, N., & Reith, D. (2012, November-December). Development of a structural population PKPD model to describe the effect of paracetamol on the international normalised ratio (INR). Poster session presented at the 9th Biennial Globalization of Pharmaceutics Education Network (GPEN) Conference, Melbourne, Australia.
Conference Contribution - Verbal presentation and other Conference outputs
Medlicott, N. (2012, November-December). Multivariate analysis of protein in solid matrices [Short course]. Verbal presentation at the 9th Biennial Globalization of Pharmaceutics Education Network (GPEN) Conference, Melbourne, Australia.
Hanning, S., Yu, T., Medlicott, N., Kieser, J., & Jones, D. (2012, November-December). Rheological characterisation of lecithin-based emulsions for potential use as a saliva substitute in patients with xerostomia. Verbal presentation at the 9th Biennial Globalization of Pharmaceutics Education Network (GPEN) Conference, Melbourne, Australia.
Medlicott, N. J., Reith, D. M., McCaffrey, F., Krittaphol, W., & Broadbent, R. S. (2012, August-September). Infusion variables impact on delivery of gentamicin to neonates - especially low birth weight neonates. Verbal presentation at the New Zealand Hospital Pharmacists' Association Conference, Auckland, New Zealand.
Hanning, S., Yu, T., Kieser, J., Jones, D. S., & Medlicott, N. J. (2012, August-September). Oily systems as saliva substitutes in xerostomia. Verbal presentation at the New Zealand Hospital Pharmacists' Association Conference, Auckland, New Zealand.
Medlicott, N. J., Chary, S., van Rij, A., & Jones, G. (2012, August-September). Doxycycline tissue levels in abdominal aortic aneurysm (AAA) patients. Verbal presentation at the New Zealand Hospital Pharmacists' Association Conference, Auckland, New Zealand.
Medlicott, N. (2012, February). Use of proteins as therapeutic agents. Invited presentation at the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
2011
Journal - Research Article
Pinholt, C., Hartvig, R. A., Medlicott, N. J., & Jorgensen, L. (2011). The importance of interfaces in protein drug delivery: Why is protein adsorption of interest in pharmaceutical formulations? Expert Opinion on Drug Delivery, 8(7), 949-964. doi: 10.1517/17425247.2011.577062
Conference Contribution - Published proceedings: Abstract
Owens, K. H., Reith, D. M., Medlicott, N. J., Zacharias, M., & Chary, S. (2011). The effect of surgery on the glucuronidation and sulphation of paracetamol. Proceedings of the Population Approach Group in Australia and New Zealand Meeting (PAGANZ). PAGANZ. Retrieved from http://www.paganz.org/default.asp?id=45&keuze=program
Conference Contribution - Poster Presentation (not in published proceedings)
Salis, E., Reith, D., & Medlicott, N. (2011, February). Liquid chromatography–mass spectrometry (LC-MS) analysis of insulin analogues for pharmacokinetic studies. Poster session presented at the New Zealand Chapter of the Controlled Release Society 13th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
Owens, K., Reith, D., Medlicott, N., Zacharias, M., & Chary, S. (2011, February). The effect of surgery on the glucuronidation and sulphation of paracetamol. Poster session presented at the New Zealand Chapter of the Controlled Release Society 13th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Fothergill, J., McDowell, A., & Medlicott, N. (2011, February). Effect of formulation on the pharmacodynamics of the anaesthetic tribromoethanol in laboratory mice. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 13th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
Guzman, P., Baldursdottir, S., Jorgensen, L., Strachan, C., Rades, T., & Medlicott, N. (2011, February). Prediction of native protein concentration using FTIR, fluorescence and multivariate analysis. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 13th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
Medlicott, N. (2011, February). Matching dosage form and drug delivery to clinical need. Invited presentation at the New Zealand Chapter of the Controlled Release Society 13th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
2010
Journal - Research Article
Wu, Z., Tucker, I. G., Razzak, M., McSporran, K., & Medlicott, N. J. (2010). Tissue compatibility and pharmacokinetics of three potential subcutaneous injectables for low-pH drug solutions. Journal of Pharmacy & Pharmacology, 62(7), 873-882. doi: 10.1211/jpp.62.07.0008
Wu, Z., Tucker, I. G., Razzak, M., Yang, L., McSporran, K., & Medlicott, N. J. (2010). Absorption and tissue tolerance of ricobendazole in the presence of hydroxypropyl-β-cyclodextrin following subcutaneous injection in sheep. International Journal of Pharmaceutics, 397, 96-102. doi: 10.1016/j.ijpharm.2010.07.002
Journal - Research Other
Al-Sallami, H., Jordan, S., Ferguson, R., Medlicott, N. J., Schollum, J., & Duffull, S. B. (2010). Current enoxaparin dosing guidelines have dubious credibility [Viewpoint]. New Zealand Medical Journal, 123(1313). Retrieved from http://journal.nzma.org.nz/journal/123-1313/4076/content.pdf
Conference Contribution - Published proceedings: Abstract
Nagaraja, R. Y., Reynolds, J. N. J., Medlicott, N. J., & Empson, R. M. (2010). Sustained drug release to the cerebellum using ELVAX polymer implants. In B. Leitch (Ed.), Proceedings of the 28th International Australasian Winter Conference on Brain Research. 28, (pp. 44). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2010.htm
Guzman, P., Jorgensen, L., Strachan, C., Rades, T., & Medlicott, N. (2010). Multivariate analysis of protein physical stability. In L. Emmerton, A. Peters, D. Ross & B. Ross (Eds.), Proceedings of the Australasian Pharmaceutical Science Association (APSA) Annual Conference: Focus on the Future: Research and Education for a Healthier Community. (pp. 42). APSA. [Abstract]
Salis, E., Reith, D., & Medlicott, N. J. (2010). Liquid Chromatography-Mass Spectrometry (LCMS) analysis of insulin analogues for pharmacokinetic studies. In L. Emmerton, A. Peters, D. Ross & B. Ross (Eds.), Proceedings of the Australasian Pharmaceutical Science Association (APSA) Annual Conference: Focus on the Future: Research and Education for a Healthier Community. (pp. 113). APSA. [Abstract]
Medlicott, N. J., Chary, S., Johnstone, G., & Jones, G. (2010). Doxycycline tissue levels in abdominal aortic aneurysm (AAA) patients. Journal of Pharmacy and Pharmacology. 62(10), (pp. 1226-1227). doi: 10.1111/j.2042-7158.2010.01178.x
Conference Contribution - Verbal presentation and other Conference outputs
Salis, E., Reith, D., & Medlicott, N. J. (2010, February). LC-MS and chemiluminescence analysis of insulin analogues for pharmacokinetic studies. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 12th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
Nagaraja, R. Y., Reynolds, J. N. J., Medlicott, N. J., & Empson, R. M. (2010, February). Polymeric devices for the delivery of neuroactive compounds to the cerebellum in vivo. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 12th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
Medlicott, N. J., Hildebrandt, C., Jørgensen, L., & Empson, R. (2010, February). Formulation strategies for controlled delivery of brain derived neurotropic factor (BDNF) to the brain. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 12th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
Other Research Output
Medlicott, N. (2010, August). Drug delivery: Getting the best out of medicines. University of Otago School of Pharmacy Seminar, Dunedin, New Zealand. [Department Seminar].
2009
Journal - Research Article
Tantipolphan, R., Rades, T., & Medlicott, N. J. (2009). Swelling lecithin: Cholesterol implants for the controlled release of proteins. Journal of Liposome Research, 19(1), 37-48. doi: 10.1080/08982100802636434
Sherwin, C. M. T., Kostan, E., Broadbent, R. S., Medlicott, N. J., & Reith, D. M. (2009). Evaluation of the effect of intravenous volume expanders upon the volume of distribution of gentamicin in septic neonates. Biopharmaceutics & Drug Disposition, 30(5), 276-280. doi: 10.1002/bdd.666
Sherwin, C. M. T., Svahn, S., Van Der Linden, A., Broadbent, R. S., Medlicott, N. J., & Reith, D. M. (2009). Individualised dosing of amikacin in neonates: A pharmacokinetic/pharmacodynamic analysis. European Journal of Clinical Pharmacology, 65(7), 705-713. doi: 10.1007/s00228-009-0637-4
Reith, D., Medlicott, N. J., De Silva, R. K., Yang, L., Hickling, J., & Zacharias, M. (2009). Simultaneous modelling of the Michaelis-Menten kinetics of paracetamol sulphation and glucuronidation. Clinical & Experimental Pharmacology & Physiology, 36(1), 35-42. doi: 10.1111/j.1440-1681.2008.05029.x
Braund, R., Hook, S. M., Greenhill, N., & Medlicott, N. J. (2009). Distribution of fibroblast growth factor-2 (FGF-2) within model excisional wounds following topical application. Journal of Pharmacy & Pharmacology, 61(2), 193-200. doi: 10.1211/jpp/61.02.0008
Sherwin, C. M. T., McCaffrey, F., Broadbent, R. S., Reith, D. M., & Medlicott, N. J. (2009). Discrepancies between predicted and observed rates of intravenous gentamicin delivery for neonates. Journal of Pharmacy & Pharmacology, 61(4), 465-471. doi: 10.1211/jpp/61.04.0008
Wu, Z., Tucker, I. G., Razzak, M., & Medlicott, N. J. (2009). Stability of ricobendazole in aqueous solutions. Journal of Pharmaceutical & Biomedical Analysis, 49(5), 1282-1286. doi: 10.1016/j.jpba.2009.02.032
Journal - Research Other
Sherwin, C. M. T., Broadbent, R. S., Medlicott, N. J., & Reith, D. M. (2009). Individualised dosing of amikacin in neonates [Letter to the editor]. European Journal of Clinical Pharmacology, 65(12), 1267-1268. doi: 10.1007/s00228-009-0691-y
Conference Contribution - Published proceedings: Full paper
Wu, Z., Tucker, I. G., Razzak, M., & Medlicott, N. J. (2009). A water-in-oil emulsion system for parenteral delivery of an acidic drug solution. Proceedings of the 36th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] St. Paul, MN: CRS. [Full Paper]
Conference Contribution - Published proceedings: Abstract
Wu, Z., Tucker, I., Razzak, M., & Medlicott, N. (2009). Skin temperature as a measure of injection site reactions following subcutaneous injection in sheep. In S. Aldous, G. Peterson, G. Jacobson & L. Bereznicki (Eds.), Proceedings of the Australasian Pharmaceutical Science Association (APSA) Annual Conference in conjunction with the Australian Controlled Release Society (Aus-CRS) Symposium. (pp. 139). APSA. [Abstract]
Reith, D., Owens, K., Svahn, S., Broadbent, R., Medlicott, N., & Sherwin, C. (2009). A pharmacokinetic pharmacodynamic study of hearing impairment in neonates treated with aminoglycosides using a logistic regression model. Basic & Clinical Pharmacology & Toxicology, 105(Suppl. 1), (pp. 131). doi: 10.1111/j.1742-7843.2009.00437.x
Conference Contribution - Poster Presentation (not in published proceedings)
Wu, Z., Tucker, I., Razzak, M., & Medlicott, N. (2009, July). A water-in-oil emulsion system for parenteral delivery of an acidic drug solution. Poster session presented at the 36th Annual Meeting & Exposition of the Controlled Release Society, Copenhagen, Denmark.
Conference Contribution - Verbal presentation and other Conference outputs
Al-Sallami, H., La, S., Moon, J., Noh, L., Yeat, N., & Medlicott, N. (2009, September). Assessing the physical stability of drug combinations in subcutaneous syringes. Verbal presentation at the New Zealand Hospital Pharmacists' Association Conference, Nelson, New Zealand.
Al-Sallami, H. S., Jordan, S., Ferguson, R., Medlicott, N. J., Schollum, J., & Duffull, S. B. (2009, September). Are enoxaparin dosing guidelines credible? Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Annual Scientific Meeting, Dunedin, New Zealand.
Medlicott, N. (2009, February). Macromolecule delivery via the oral route: Current innovations. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 11th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
2008
Journal - Research Article
Sherwin, C., Broadbent, R., Young, S., Worth, J., McCaffrey, F., Medlicott, N. J., & Reith, D. (2008). Utility of interleukin-12 and interleukin-10 in comparison with other cytokines and acute-phase reactants in the diagnosis of neonatal sepsis. American Journal of Perinatology, 25, 629-636. doi: 10.1055/s-0028-1090585
Al-Sallami, H., Ferguson, R., Wilkins, G., Gray, A., & Medlicott, N. J. (2008). Bleeding events in patients receiving enoxaparin for the management of non-ST-elevation acute coronary syndrome (NSTEACS) at Dunedin Public Hospital, New Zealand. New Zealand Medical Journal, 121(1285). Retrieved from http://journal.nzma.org.nz/journal/121-1285/3342/content.pdf
Sherwin, C. M. T., Broadbent, R. S., Medlicott, N. J., & Reith, D. M. (2008). Individualising netilmicin dosing in neonates. European Journal of Clinical Pharmacology, 64, 1201-1208. doi: 10.1007/s00228-008-0536-0
Tantipolphan, R., Rades, T., & Medlicott, N. J. (2008). Insights into the structure of protein by vibrational spectroscopy. Current Pharmaceutical Analysis, 4, 53-68.
Journal - Research Other
Sherwin, C. M. T., Svahn, S., Broadbent, R. S., Van Der Linden, A., Medlicott, N. J., & Reith, D. M. (2008). Netilmicin withdrawal: Impact on neonates [Letter]. New Zealand Medical Journal, 121(1284). Retrieved from http://journal.nzma.org.nz/journal/121-1284/3328/content.pdf
Journal - Professional & Other Non-Research Articles
Sherwin, C., Medlicott, N., Broadbent, R., & Reith, D. (2008). Neonatal sepsis and aminoglycosides. Pharmacy Journal of New Zealand, (April), 16-20.
Conference Contribution - Published proceedings: Abstract
Owens, K., Sherwin, C., Reith, D., & Medlicott, N. (2008). Evaluating gentamicin and ototoxicity in neonates to optimise development of a new dosing regimen. New Zealand Medical Journal, 121(1274). Retrieved from http://journal.nzma.org.nz/journal/121-1274/3078/content.pdf
Owens, K., Sherwin, C. M. T., Broadbent, R., Reith, D. M., & Medlicott, N. J. (2008). Investigation of hearing impairment in neonates treated with aminoglycosides. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Annual Scientific Meeting. ASCEPT. Retrieved from http://phal.otago.ac.nz/ascept_docos/programme%202008.pdf
Sherwin, C. M. T., Svahn, S., van der Linden, A. J., Medlicott, N. J., Broadbent, R., & Reith, D. M. (2008). Withdrawing medicines used to treat infections in neonates may increase the risk of treatment failure. In C. Matthewson & M. Taumoepeau (Eds.), Proceedings of the Pacific Postgraduate Symposium: Pacific Voices V. (pp. 41). Dunedin, New Zealand: Pacific Islands Centre, University of Otago. [Abstract]
Sherwin, C. M. T., Svahn, S., Medlicott, N. J., Broadbent, R., & Reith, D. M. (2008). Pharmacodynamic analysis of hearing impaired neonates treated with amikacin. Proceedings of the American Conference on Pharmacometrics. ACOP. Retrieved from http://tucson2008.go-acop.org/pdfs/Sherwin.pdf
Medlicott, N. J., McCorquodale, C., & Tordoff, J. (2008). Compatibility studies for an opioid and anti-emetic in Graseby pump syringes. Journal of Pharmacy and Pharmacology. (Suppl. 1), (pp. A-32-A-33). [Abstract]
Medlicott, N. J., Rizi, K., Yang, L., Zacharias, M., De Silva, R. K., & Reith, D. M. (2008). Does reduced dissolution of paracetamol contribute to delayed absorption following single 60 and 90 mg/kg doses in third molar extractions? Journal of Pharmacy and Pharmacology. (Suppl. 1), (pp. A-33-A-34). [Abstract]
Medlicott, N. J., Sherwin, C., Broadbent, R., McCaffrey, F., & Reith, D. (2008). Intravenous infusions of gentamicin in neonate patients: Effects of infusion variables on drug administration rates. Journal of Pharmacy and Pharmacology. (Suppl. 1), (pp. A-11). [Abstract]
Sherwin, C. M. T., Svahn, S., Van Der Linden, A. J., Medlicott, N. J., Broadbent, R., & Reith, D. M. (2008). Simulation of an optimal pharmacokinetic and pharmacodynamic amikacin dosing regimen for neonates. Proceedings of the 10th Annual Population Approach Group in Australia and New Zealand Conference. PAGANZ. Retrieved from http://www.paganz.org/default.asp?abstract=1077
Sherwin, C. M. T., Medlicott, N. J., Broadbent, R., & Reith, D. M. (2008). Simulation and development of a netilmicin extended dosing regimen for extremely premature neonates. Proceedings of the Seventeenth Meeting of the Population Approach Group in Europe. PAGE. Retrieved from http://www.page-meeting.org/default.asp?abstract=1241
Conference Contribution - Verbal presentation and other Conference outputs
Braund, R., Hook, S. M., Greenhill, N. S., & Medlicott, N. J. (2008, February). Confocal microscopy to determine intra-wound distribution of FGF-2 following topical application. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 10th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
Medlicott, N. (2008, October). Peptide and protein stability in solution. Verbal presentation at the New Zealand and Australian Chapters of the Controlled Release Society 2 Day Workshop, Dunedin, New Zealand.
Medlicott, N. (2008, October). Formulations for ″proof of concept″ studies. Verbal presentation at the New Zealand and Australian Chapters of the Controlled Release Society 2 Day Workshop, Dunedin, New Zealand.
Medlicott, N. (2008, October). Formulations for ″proof of concept″ studies. Verbal presentation at the New Zealand and Australian Chapters of the Controlled Release Society 2 Day Workshop, Brisbane, Australia.
Medlicott, N. (2008, October). Peptide and protein stability in solution. Verbal presentation at the New Zealand and Australian Chapters of the Controlled Release Society 2 Day Workshop, Brisbane, Australia.
Medlicott, N. (2008, February). Towards understanding of protein behaviour in subcutaneous phospholipid implants. Verbal presentation at the New Zealand Chapter of the Controlled Release Society 10th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
Sherwin, C. M. T., Medlicott, N. J., Broadbent, R., & Reith, D. M. (2008, June). Investigation into the intravenous delivery of aminoglycoside antibiotics to extremely premature neonates. Verbal presentation at the 11th Biannual European Society for Developmental Perinatal and Paediatric Pharmacology Congress, Rotterdam, The Netherlands.
2007
Journal - Research Article
Braund, R., Hook, S., & Medlicott, N. J. (2007). The role of topical growth factors in chronic wounds. Current Drug Delivery, 4(3), 195-204. doi: 10.2174/156720107781023857
Braund, R., Tucker, I. G., & Medlicott, N. J. (2007). Hypromellose films for the delivery of growth factors for wound healing. Journal of Pharmacy & Pharmacology, 59(3), 367-372.
Zacharias, M., De Silva, R. K., Hickling, J., Medlicott, N. J., & Reith, D. M. (2007). Comparative safety and efficacy of two high dose regimens of oral paracetamol in healthy adults undergoing third molar surgery under local anaesthesia. Anaesthesia & Intensive Care, 35(4), 544-549.
Tantipolphan, R., Rades, T., McQuillan, A. J., & Medlicott, N. J. (2007). Adsorption of bovine serum albumin (BSA) onto lecithin studied by attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy. International Journal of Pharmaceutics, 337, 40-47.
Journal - Professional & Other Non-Research Articles
Tantipolphan, R., Rades, T., & Medlicott, N. J. (2007). Swellable lipid implants: Use of vibrational spectroscopy to study lipid and protein structure. Controlled Release Society Newsletter, 24(4), 14-16.
Conference Contribution - Published proceedings: Full paper
Tantipolphan, R., Rades, T., & Medlicott, N. J. (2007). Lecithin-cholesterol implants for a controlled release of proteins. Proceedings of the 34th Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]
Conference Contribution - Published proceedings: Abstract
Sherwin, C. M. T., Svahn, S., Van Der Linden, A. J., Medlicott, N. J., Broadbent, R., & Reith, D. M. (2007). A pharmacokinetic/pharmacodynamic model to determine optimal dosing targets for amikacin in neonatal sepsis. Proceedings of the Population Approach Group in Europe Sixteenth Annual Meeting. PAGE. Retrieved from http://www.page-meeting.org/default.asp?abstract=1134
Sherwin, C. M. T., Broadbent, R., Medlicott, N. J., & Reith, D. M. (2007). Investigation into the diagnosis of neonatal sepsis and improvement of treatment utilising the pharmacokinetics of aminoglycosides. In C. Matthewson & M. Taumoepeau (Eds.), Proceedings of the Pacific Postgraduate Symposium: Pacific Voices IV. (pp. 37). Dunedin, New Zealand: Pacific Islands Centre, University of Otago. [Abstract]
Braund, R., Medlicott, N., & Hook, S. (2007). Distribution of fibroblast growth factor-2 within excisional wounds following topical application in rats. New Zealand Medical Journal, 120(1262). Retrieved from http://journal.nzma.org.nz/journal/120-1262/2740/content.pdf
Conference Contribution - Poster Presentation (not in published proceedings)
Tantipolphan, R., Rades, T., & Medlicott, N. (2007, November). Principal component analysis: An alternative approach for the investigation of lipid-salt interaction using infrared and Raman spectroscopy. Poster session presented at the American Association of Pharmaceutical Scientists Annual Meeting and Exposition, San Diego, CA.
Braund, R., Hook, S., Greenhill, N., & Medlicott, N. (2007, July). Distribution of FGF-2 within excisional wounds following topical application. Poster session presented at the 34th Annual Meeting & Exposition of the Controlled Release Society, Long Beach, CA. Retrieved from http://www.nzma.org.nz/journal/120-1262/2740/content.pdf
Al-Sallami, H., Ferguson, R., Medlicott, N., Wilkins, G., & Gray, A. (2007, August). Incidents and predictors of bleeding in non-st-elevation acute coronary syndrome patients treated with enoxaparin. Poster session presented at the Australasian Society of Clinical and Experimental Pharmacologists & Toxicologists (NZ) Annual Scientific Meeting, Auckland, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Medlicott, N. (2007, July). Physiological variables influencing product performance. Verbal presentation at the 34th Annual Meeting & Exposition of the Controlled Release Society, Long Beach, CA.
Sherwin, C. M. T., Kostan, E., Medlicott, N. J., Broadbent, R., & Reith, D. M. (2007, August). The effect upon volume of distribution of intravenous volume expanders delivered to neonates treated with gentamicin for suspected sepsis. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists & Toxicologists (NZ) Annual Scientific Meeting, Auckland, New Zealand.
Al-Sallami, H., Ferguson, R., Medlicott, N., & Wilkins, G. (2007, September). Bleeding associated with enoxaparin in patients treated for non-ST-elevation acute coronary syndrome at Dunedin Hospital. Verbal presentation at the New Zealand HealthCare Pharmacists' Association Conference, Wellington, New Zealand.
(Sun) Tantipolphan, R., Rades, T., & Medlicott, N. (2007, February). The effects of salts on the release of protein from lipid implants. Verbal presentation at the 9th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.
2006
Journal - Research Article
Tantipolphan, R., Rades, T., Strachan, C. J., Gordon, K. C., & Medlicott, N. J. (2006). Analysis of lecithin-cholesterol mixtures using Raman spectroscopy. Journal of Pharmaceutical & Biomedical Analysis, 41, 476-484.
Milak, S., Medlicott, N., & Tucker, I. G. (2006). Solid lipid microparticles containing loratadine prepared using a Micromixer. Journal of Microencapsulation, 23(8), 823-831.
Conference Contribution - Published proceedings: Full paper
Wu, Z., Tucker, I. G., & Medlicott, N. J. (2006). In vitro/in vivo cellular damage and pharmacokinetics of a hydroxypropyl-β-cyclodextrin solution of ricobendazole. Proceedings of the 33rd Annual Meeting & Exposition of the Controlled Release Society. [CD-ROM] Minnesota, USA: CRS. [Full Paper]
Conference Contribution - Published proceedings: Abstract
Hickling, J. M., De Silva, R. K., Zacharias, M., Reith, D., & Medlicott, N. (2006). Comparison of two different doses of paracetamol for pain relief in day care dental procedures. Anaesthesia & Intensive Care, 34(4), (pp. 544-545). [Abstract]
Tantipolphan, R., Boustead, A., Rades, T., McQuillan, J., & Medlicott, N. (2006). Attenuated Total Reflectance (ATR) Infrared Spectroscopy as a technique to study the effects of formulation excipients (salts) on protein-phospholipid interfacial interactions. AAPS Journal, 8(S2). Retrieved from http://www.aapsj.org/abstracts/AM_2006/AAPS2006-001677.pdf
Sherwin, C. M. T., Svahn, S., Medlicott, N., Broadbent, R., & Reith, D. M. (2006). Population pharmacokinetics of amikacin in extremely low birth weight to term neonates. AAPS Journal, 8(S2). Retrieved from http://www.aapsj.org/abstracts/AM_2006/AAPS2006-000310.pdf
Conference Contribution - Poster Presentation (not in published proceedings)
Tantipolphan, R., Boustead, A., McQuillan, A. J., Rades, T., & Medlicott, N. J. (2006, October). BSA adsorption onto lecithin films: Effects of NaC1 and CaC12 concentrations. Poster session presented at the 6th Biennal Globalization of Pharmaceutics Education Network Conference, Kansas, USA.
Braund, R., Hook, S. M., & Medlicott, N. J. (2006, July). Protein release from hydroxypropylmethylcellulose (HPMC) films. Poster session presented at the 33rd Annual Meeting & Exposition of the Controlled Release Society, Vienna, Austria.
Conference Contribution - Verbal presentation and other Conference outputs
Medlicott, N. (2006, August). Absorption of single dose paracetamol (60 and 90mg/kg) in third molar extractions: Dissolution or gastric emptying rate limited? Verbal presentation at the Pharmacy School Seminar Series, Dunedin, New Zealand.
Braund, R., Hook, S. M., & Medlicott, N. J. (2006, February). Protein release from hydroxypropylmethylcellulose (HPMC) films. Verbal presentation at the 8th Conference on Formulation & Delivery of Bioactives in Association with the New Zealand Chapter Controlled Release Society, Dunedin, New Zealand.
2005
Journal - Research Article
Wu, Z., Tucker, I. G., Razzak, M., & Medlicott, N. J. (2005). An in vitro kinetic method for detection of precipitation of poorly soluble drugs. International Journal of Pharmaceutics, 304, 1-3.
Wu, Z., Medlicott, N. J., Razzak, M., & Tucker, I. G. (2005). Development and optimization of a rapid HPLC method for analysis of ricobendazole and albendazole sulfone in sheep plasma. Journal of Pharmaceutical & Biomedical Analysis, 39(5), 225-232.
Wu, Z., Razzak, M., Tucker, I. G., & Medlicott, N. J. (2005). Physicochemical characterization of ricobendazole: I. Solubility, lipophilicity, and ionization characteristics. Journal of Pharmaceutical Sciences, 94(5), 983-993.
Conference Contribution - Published proceedings: Abstract
Tantipolphan, R., Chiruvelli, R., Tucker, I. G., Clark, D., Haines, S., & Medlicott, N. J. (2005). Stability indicating HPLC assays for an angiogenic extract from deer velvet. Proceedings of the 7th Conference of Formulation and Delivery of Bioactives in association with the New Zealand Chapter of the Controlled Release Society. Dunedin, New Zealand: University of Otago. [Abstract]
Tantipolphan, R., Rades, T., Strachan, C. J., Gordon, K. C., & Medlicott, N. J. (2005). Lecithin and cholesterol interaction studied by Raman spectroscopy. Proceedings of the 2nd AASP Symposium and 2nd APEM Conference. (pp. 207-209). Bangkok, Thailand. [Abstract]
Medlicott, N. (2005). Chemical stability of protein bioactives. Proceedings of the 7th Conference of Formulation and Delivery of Bioactives in association with the New Zealand Chapter of the Controlled Release Society. Dunedin, New Zealand: University of Otago. [Abstract]
Braund, R., Tucker, I., & Medlicott, N. (2005). Hydroxypropylmethylcellulose systems for the delivery of growth factors for wound healing. Proceedings of the American Association of Pharmaceutical Scientists. 7(s2). [Abstract]
Tantipolphan, R., Rades, T., Gordon, K., & Medlicott, N. (2005). Interactions between lecithin and cholesterol measured by Raman spectroscopy. AAPS Journal, 7(S2). Retrieved from http://www.aapsj.org/abstracts/AM_2005/AAPS2005-003101.pdf
Conference Contribution - Verbal presentation and other Conference outputs
Braund, R., Tucker, I. G., & Medlicott, N. J. (2005, February). Model protein release from hydroxypropylmethylcellulose systems. Verbal presentation at the Formulation and Delivery of Bioactives 7th Conference in association with the New Zealand Chapter of the Controlled Release Society, Dunedin, New Zealand.
2004
Journal - Research Article
Medlicott, N. J., Waldron, N. A., & Foster, T. P. (2004). Sustained release veterinary parenteral products. Advanced Drug Delivery Reviews, 56, 1345-1365.
Pongjanyakul, T., Medlicott, N. J., & Tucker, I. G. (2004). Melted glyceryl palmitostearate (GPS) pellets for protein delivery. International Journal of Pharmaceutics, 271, 53-62.
Conference Contribution - Published proceedings: Abstract
Wu, Z., Tucker, I., Razzak, M., McSporran, K., & Medlicott, N. (2004). In vitro characterization of potential ricobendazole 5% w/v subcutaneous injections. The American Association of Pharmaceutical Scientists Meeting. 6(4). [Abstract]
Wu, Z., Tucker, I., Razzak, M., McSporran, K., & Medlicott, N. (2004). In vitro/in vivo cellular damage and pharmacokinetics of potential ricobendazole subcutaneous injections. AAPS Journal, 6(Suppl. 1), (pp. T3113). [Abstract]
Braund, R., Tucker, I. G., & Medlicott, N. J. (2004). Hydroxypropylmethylcellulose gels as topical formulations for wound healing. Proceedings of the Annual Conference of the Australasian Pharmaceutical Science Association. (pp. 125). Melbourne, Australia: APSA. [Abstract]
Tantipolphan, R., Chiruvelli, R., Tucker, I. G., Clark, D., Haines, S., Davis, P., & Medlicott, N. J. (2004). Gel formulations of an angiogenic extract from deer velvet for wound healing. Proceedings of the Annual Conference of the Australasian Pharmaceutical Science Association. (pp. 115). Melbourne, Australia: APSA. [Abstract]
2003
Journal - Research Article
Slobbe, L., Medlicott, N., Lockhart, E., Davies, N., Tucker, I., Razzak, M., & Buchan, G. (2003). A prolonged immune response to antigen delivered in poly (∈-caprolactone) microparticles. Immunology & Cell Biology, 81, 185-191. doi: 10.1046/j.1440-1711.2003.01155.x
Conference Contribution - Verbal presentation and other Conference outputs
Medlicott, N. (2003, July). Parenteral drug delivery: Challenges and opportunities in animal health. Verbal presentation at the Shared Concepts and Challenges in Human and Animal Health Workshop
2002
Conference Contribution - Published proceedings: Abstract
Medlicott, N., Pongjanyakul, T., & Tucker, I. (2002). Melted and compressed glyceryl palmitostearate pellets for protein delivery. The American Association of Pharmaceutical Scientists: PharmSci. 4(4), (pp. T3290). [Abstract]
Medlicott, N. (2002). Chromatographic techniques for protein characterisation in pharmaceutical formulations. Proceedings of the 5th Conference of Formulation and Delivery of Bioactives in association with the New Zealand Chapter of the Controlled Release Society. Dunedin, New Zealand: University of Otago. [Abstract]
Wu, Z., Razzak, M., Tucker, I. G., & Medlicott, N. (2002). Solubility, lipophilicity, ionization and stability of ricobendazole. Abstracts of the Australasian Pharmaceutical Sciences Association Conference. (pp. 138). Melbourne, Australia. [Abstract]
2001
Conference Contribution - Published proceedings: Abstract
Medlicott, N. J., Desari, V. R., Razzak, M., & Tucker, I. G. (2001). Microencapsulation of vitamin B12 in ethylcellulose for prolonged continuous release. The American Association of Pharmaceutical Scientists: PharmSci. 3(3). [Abstract]
Medlicott, N. J., Desari, V. R., Razzak, M., & Tucker, I. G. (2001). Microencapsulation of a model protein (bovine serum albumin, BSA) with poly(e-caprolactone), PCL, using a modified water-in-oil-in-water (w/o1/o2) technique. The American Association of Pharmaceutical Scientists: PharmSci. 3(3). [Abstract]
Medlicott, N. J., Higgins, A. H., & Kennedy, J. M. (2001). Use of web-based teaching for a distance paper. Proceedings of the Australasian Pharmaceutical Science Association Annual Conference. (pp. 142). Melbourne: APSA. [Abstract]
Medlicott, N. J., Chary, S., Razzak, M., & Tucker, I. G. (2001). Blended polymer microspheres for the controlled release of a model protein bioactive. Proceedings of the Australasian Pharmaceutical Science Association Annual Conference. (pp. 86). Melbourne: APSA. [Abstract]
1999
Journal - Research Article
Medlicott, N. J., Holborow, D. W., Rathbone, M. J., Jones, D. S., & Tucker, I. G. (1999). Local delivery of chlorhexidine using a tooth-bonded delivery system. Journal of Controlled Release, 61(3), 337-343. doi: 10.1016/S0168-3659(99)00152-2
Journal - Research Other
Medlicott, N. J., & Tucker, I. G. (1999). Pulsatile release from subcutaneous implants. Advanced Drug Delivery Reviews, 38, 139-149. doi: 10.1016/S0169-409X(99)00013-7
1998
Journal - Research Article
Medlicott, N. J., Foster, K. A., Audus, K. L., Gupta, S., & Stella, V. J. (1998). Comparison of the effects of potential parenteral vehicles for poorly water soluble anticancer drugs (organic cosolvents and cyclodextrin solutions) on cultered endothelial cells (HUV-EC). Journal of Pharmaceutical Sciences, 87, 1138-1143.
Conference Contribution - Published proceedings: Abstract
Medlicott, N. J., Kalanie, S., Holborow, D. W., & Tucker, I. G. (1998). Light-cured dental restorative materials for controlled release of chlorhexidine. Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Programme. (pp. 78). [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Medlicott, N. J., Kalanie, S., Holborow, D. W., & Tucker, I. G. (1998). Restorative dental materials as controlled-release devices for chlorhexidine. Verbal presentation at the Australian Pharmeceuticals Association Conference, Hobart, Australia.
Jones, D. S., Medlicott, N. J., Rathbone, M., Holborow, D. W., & Tucker, I. G. (1998). Controlled, localised delivery of chlorhexidine for inhibition of plaque formation. Verbal presentation at the British Pharmacological Conference, UK.
1996
Journal - Research Article
Medlicott, N. J., Tucker, I. G., Rathbone, M. J., Holborow, D. W., & Jones, D. J. (1996). Chlorhexidine release from poly (ε-caprolactone) films prepared by solvent evaporation. International Journal of Pharmaceutics, 143(1), 25-35. doi: 10.1016/S0378-5173(96)04675-3
1995
Journal - Research Article
Medlicott, N. J., Tucker, I. G., Holborow, D. W., & Rathbone, M. J. (1995). Liquid chromatographic analysis of chlorhexidine at specific sites in the saliva film after application of a tooth-bonded delivery system. Journal of Liquid Chromatography, 18(11), 2193-2204. doi: 10.1080/10826079508010264