Professor Gillian Whalley

Contact Details
- Phone
- +64 21 306 509
- gillian.whalley@otago.ac.nz
University Links
- Position
- Professor of Clinical Sonography / Cardiology
- Department
- Department of Medicine (Dunedin)
- Qualifications
- BAppSci MHSc(Hons) DMU PhD
- Research summary
- Cardiovascular disease
- Teaching
- ELM3 Early Professional Experience, Sonography
- Clinical
- Clinical echocardiography
Research
I am interested in the appropriate use of echocardiography to identify factors that may contribute to higher risk in patients and in at-risk populations. A key future focus will be community-based screening using ultrasound to identify individuals at higher risk of developing cardiovascular disease in order to introduce preventative methods early.
I have a long-term interest in the relationship between body composition and heart size and the impact of ethnicity upon that. I have recently completed an HRC-funded study evaluating heart size in Aotearoa/New Zealand, with a particular emphasis on determining what reference ranges should be applied in here.
I have experience of small single-centre and large multi-centre clinical trials, cohort studies, and prognostic studies, and have used meta-analytical methods widely. My interest in meta-analysis (both literature and individual patient approaches) extends towards linking echocardiography measurements with improved clinical correlation and prognosis in large population studies.
Publications
Sugunesegran, R., Harrison, S., Parry, D., Sneddon, K., de Lange, M., Galvin, S., … Whalley, G., Davis, P., & Coffey, S. (2023). Ethnicity Is associated with differing presentation and outcomes of patients undergoing aortic valve replacement for calcific aortic stenosis in Aotearoa New Zealand. Heart, Lung & Circulation. Advance online publication. doi: 10.1016/j.hlc.2023.08.016
Moore, M. K., Jones, G. T., Whalley, G., Prendergast, B., Williams, M. J. A., & Coffey, S. (2023). Outcomes of patients with early calcific aortic valve disease detected by clinically indicated echocardiography. European Heart Journal: Cardiovascular Imaging. Advance online publication. doi: 10.1093/ehjci/jead259
Beck, S., & Whalley, G. (2023). POCUS is everywhere. Australasian Journal of Ultrasound in Medicine, 26(2), 73-74. doi: 10.1002/ajum.12349
Whalley, G. (2023). Clinical ultrasound research influences clinical ultrasound practice. Australasian Journal of Ultrasound in Medicine, 26(1), 3-4. doi: 10.1002/ajum.12341
Sengupta, S., Coffey, S., & Whalley, G. A. (2023). Survey of echocardiography practice across five continents. Echocardiography. Advance online publication. doi: 10.1111/echo.15550
Francis, J. R., Fairhurst, H., Yan, J., Fernandes Monteiro, A., Lee, A.-M., Maurays, J., … Whalley, G. A., … Remenyi, B. (2023). Abbreviated echocardiographic screening for rheumatic heart disease by non-experts with and without offsite expert review: A diagnostic accuracy study. Journal of the American Society of Echocardiography. Advance online publication. doi: 10.1016/j.echo.2023.02.007
Journal - Research Article
Moore, M. K., Jones, G. T., Whalley, G., Prendergast, B., Williams, M. J. A., & Coffey, S. (2023). Outcomes of patients with early calcific aortic valve disease detected by clinically indicated echocardiography. European Heart Journal: Cardiovascular Imaging. Advance online publication. doi: 10.1093/ehjci/jead259
Journal - Research Article
Sengupta, S., Coffey, S., & Whalley, G. A. (2023). Survey of echocardiography practice across five continents. Echocardiography. Advance online publication. doi: 10.1111/echo.15550
Journal - Research Article
Sugunesegran, R., Harrison, S., Parry, D., Sneddon, K., de Lange, M., Galvin, S., … Whalley, G., Davis, P., & Coffey, S. (2023). Ethnicity Is associated with differing presentation and outcomes of patients undergoing aortic valve replacement for calcific aortic stenosis in Aotearoa New Zealand. Heart, Lung & Circulation. Advance online publication. doi: 10.1016/j.hlc.2023.08.016
Journal - Research Article
Aitken-Buck, H. M., Moore, M., Whalley, G. A., Lohner, L., Ondruschka, B., Coffey, S., … Lamberts, R. R. (2022). Estimating heart mass from heart volume as measured from post-mortem computed tomography. Forensic Science, Medicine & Pathology, 18, 333-342. doi: 10.1007/s12024-022-00478-1
Journal - Research Article
Fordyce, A. M., Whalley, G. A., Coffey, S., & Wilson, L. C. (2022). Adjunct methods for the detection of patent foramen ovale: The contribution of transcranial Doppler and the Valsalva manoeuvre. Heart, Lung & Circulation, 31, 1471-1481. doi: 10.1016/j.hlc.2022.07.017
Journal - Research Article
Krishnan, A., Prasad, S. B., Guppy-Coles, K. B., Holland, D. J., Hammett, C., Whalley, G., … Atherton, J. J. (2022). Composite echocardiographic score to predict long-term survival following myocardial infarction. Heart, Lung & Circulation, 31, 795-803. doi: 10.1016/j.hlc.2022.01.005
Journal - Research Article
Whalley, G. A., Harrington, A., Christiansen, J., Ikenasio, B., Deo, A., Gamble, G. D., & Crengle, S. (2022). New Echocardiography Reference Ranges for Aotearoa (NewERA) Study: The application of international echocardiographic reference values to linear measurements of the hearts of healthy, young Māori and Pacific adults may not detect cardiac enlargement. New Zealand Medical Journal, 135(1558), 19-34. Retrieved from https://journal.nzma.org.nz
Journal - Research Article
Francis, J. R., Whalley, G. A., Kaethner, A., Fairhurst, H., Hardefeldt, H., Reeves, B., … Remenyi, B. (2021). Single-view echocardiography by nonexpert practitioners to detect rheumatic heart disease: A prospective study of diagnostic accuracy. Circulation: Cardiovascular Imaging, 14(8), e011790. doi: 10.1161/circimaging.120.011790
Journal - Research Article
Francis, J. R., Fairhurst, H., Hardefeldt, H., Brown, S., Ryan, C., Brown, K., … Whalley, G., … Remenyi, B. (2020). Hyperendemic rheumatic heart disease in a remote Australian town identified by echocardiographic screening. Medical Journal of Australia, 213(3), 118-123. doi: 10.5694/mja2.50682
Journal - Research Article
Moharram, M. A., Aitken-Buck, H. M., Reijers, R., van Hout, I., Williams, M. J. A., Jones, P. P., Whalley, G. A., Lamberts, R. R., & Coffey, S. (2020). Correlation between epicardial adipose tissue and body mass index in New Zealand ethnic populations. New Zealand Medical Journal, 133(1516), 22-32. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Article
Prasad, S. B., Camuglia, A., Lo, A., Holland, D. J., Guppy-Coles, K., Whalley, G., … Atherton, J. J. (2020). Hemodynamic validation of the E/e’ ratio as a measure of left ventricular filling pressure in patients with non-ST elevation myocardial infarction. American Journal of Cardiology, 125, 507-512. doi: 10.1016/j.amjcard.2019.11.010
Journal - Research Article
Adamson, P. D., McAllister, D., Pilbrow, A., Pickering, J. W., Poppe, K., Shah, A., Whalley, G., … Pemberton, C., Troughton, R. W., … Richards, A. M. (2019). Convalescent troponin and cardiovascular death following acute coronary syndrome. Heart, 105, 1717-1724. doi: 10.1136/heartjnl-2019-315084
Journal - Research Article
Prasad, S. B., Guppy-Coles, K. B., Holland, D., Stanton, T., Krishnasamy, R., Whalley, G., … Thomas, L. (2019). Echocardiographic predictors of all-cause mortality in patients with left ventricular ejection fraction >35%: Value of guideline based assessment of diastolic dysfunction. IJC Heart & Vasculature, 24, 100407. doi: 10.1016/j.ijcha.2019.100407
Journal - Research Article
Prasad, S. B., Guppy-Coles, K., Stanton, T., Armstrong, J., Krishnaswamy, R., Whalley, G., … Thomas, L. (2019). Relation of left atrial volumes in patients with myocardial infarction to left ventricular filling pressures and outcomes. American Journal of Cardiology, 124(3), 325-333. doi: 10.1016/j.amjcard.2019.05.007
Journal - Research Article
Marks, E. C. A., Wilkinson, T. M., Frampton, C. M., Skelton, L., Pilbrow, A. P., Yandle, T. G., Pemberton, C. J., … Whalley, G. A., … Troughton, R. W., … Cameron, V. A., Richards, A. M., Gieseg, S. P., & Palmer, B. R. (2018). Plasma levels of soluble VEGF receptor isoforms, circulating pterins and VEGF system SNPs as prognostic biomarkers in patients with acute coronary syndromes. BMC Cardiovascular Disorders, 18, 169. doi: 10.1186/s12872-018-0894-1
Journal - Research Article
Prasad, S. B., Lin, A. K., Guppy-Coles, K. B., Stanton, T., Krishnasamy, R., Whalley, G. A., … Atherton, J. J. (2018). Diastolic dysfunction assessed using contemporary guidelines and prognosis following myocardial infarction. Journal of the American Society of Echocardiography, 31(10), 1127-1136. doi: 10.1016/j.echo.2018.05.016
Journal - Research Article
Prickett, T. C. R., Doughty, R. N., Troughton, R. W., Frampton, C. M., Whalley, G. A., Ellis, C. J., Espiner, E. A., & Richards, A. M. (2017). C-type natriuretic peptides in coronary disease. Clinical Chemistry, 63(1), 316-324. doi: 10.1373/clinchem.2016.257816
Journal - Research Article
Badve, S. V., Palmer, S. C., Strippoli, G. F. M., Roberts, M. A., Teixeira-Pinto, A., Boudville, N., … Whalley, G. A., … Johnson, D. W. (2016). The validity of left ventricular mass as a surrogate end point for all-cause and cardiovascular mortality outcomes in people with CKD: A systematic review and meta-analysis. American Journal of Kidney Diseases, 68(4), 554-563. doi: 10.1053/j.ajkd.2016.03.418
Journal - Research Article
Berry, C., Poppe, K. K., Gamble, G. D., Earle, N. J., Ezekowitz, J. A., Squire, I. B., … Whalley, G. A., … on behalf of the MAGGIC Collaborative Group. (2016). Prognostic significance of anaemia in patients with heart failure with preserved and reduced ejection fraction: Results from the MAGGIC individual patient data meta-analysis. QJM, 109(6), 377-382. doi: 10.1093/qjmed/hcv087
Journal - Research Article
Buckley, B., Farnworth, M. J., & Whalley, G. (2016). Echocardiography service provision in New Zealand: The implications of capacity modelling for the cardiac sonographer workforce. New Zealand Medical Journal, 129(1428), 16-24. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Article
Poppe, K. K., Doughty, R. N., Whalley, G. A., & Triggs, C. M. (2016). A new approach to assessment of the left ventricle. MethodsX, 3, 274-278. doi: 10.1016/j.mex.2016.03.014
Journal - Research Article
Rigolli, M., Anandabaskaran, S., Christiansen, J. P., & Whalley, G. A. (2016). Bias associated with left ventricular quantification by multimodality imaging: A systematic review and meta-analysis. Open Heart, 3(1), e000388. doi: 10.1136/openhrt-2015-000388
Journal - Research Article
Simioniuc, A., Carluccio, E., Ghio, S., Rosi, A., Biagiolo, P., Reboldi, G., … Whalley, G., … on behalf of the investigators of the Network Labs Ultrasound (NEBULA) in Heart Failure Study Group. (2016). Echo and natriuretic peptide guided therapy improves outcome and reduces worsening renal function in systolic heart failure: An observational study of 1137 outpatients. International Journal of Cardiology, 224, 416-423. doi: 10.1016/j.ijcard.2016.09.034
Journal - Research Article
Yan, M. R., Parsons, A., Whalley, G. A., & Rush, E. C. (2016). Effects of a healthier snack on snacking habits and glycated Hb (HbA1c): A 6-week intervention study. British Journal of Nutrition, 116(12), 2169-2174. doi: 10.1017/S0007114516004372
Journal - Research Article
Buckley, B. A., Poppe, K., Farnworth, M. J., & Whalley, G. (2015). Regional differences in echocardiography provision in New Zealand: Results from the 2013 SCANZ Workforce Survey. New Zealand Medical Journal, 128(1408), 47-55. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Article
Earle, N. J., Poppe, K. K., Pilbrow, A. P., Cameron, V. A., Troughton, R. W., Skinner, J. R., … Whalley, G. A., … Richards, A. M., & Doughty, R. N. (2015). Genetic markers of repolarization and arrhythmic events following acute coronary syndromes. American Heart Journal, 169(4), 579-586.e3. doi: 10.1016/j.ahj.2014.11.015
Journal - Research Article
Jackson, C. E., Castagno, D., Maggioni, A. P., Køber, L., Squire, I. B., Swedberg, K., … Richards, A. M., … Whalley, G., … on behalf of the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC). (2015). Differing prognostic value of pulse pressure in patients with heart failure with reduced or preserved ejection fraction: Results from the MAGGIC individual patient meta-analysis. European Heart Journal, 36(18), 1106-1114. doi: 10.1093/eurheartj/ehu490
Journal - Research Article
Pinkham, M. I., Whalley, G. A., Guild, S.-J., Malpas, S. C., & Barrett, C. J. (2015). Arterial baroreceptor reflex control of renal sympathetic nerve activity following chronic myocardial infarction in male, female, and ovariectomized female rats. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 309(2), R169-R178. doi: 10.1152/ajpregu.00026.2015
Journal - Research Article
Poppe, K. K., Whalley, G. A., Doughty, R. N., Woodward, M., Patel, A., Chow, C. K., … Triggs, C. M. (2015). The development and feasibility of a composite score of echocardiographic indices that may stratify outcome in patients with diabetes mellitus. International Journal of Cardiology, 182, 244-249. doi: 10.1016/j.ijcard.2014.12.087
Journal - Research Article
Rigolli, M., Rossi, A., Quintana, M., Klein, A. L., Yu, C.-M., Ghio, S., … Troughton, R. W., … Whalley, G. A., … on behalf of the MeRGE Collaborators. (2015). The prognostic impact of diastolic dysfunction in patients with chronic heart failure and post-acute myocardial infarction: Can age-stratified E/A ratio alone predict survival? International Journal of Cardiology, 181, 362-368. doi: 10.1016/j.ijcard.2014.12.051
Journal - Research Article
Simpson, J., Castagno, D., Doughty, R. N., Poppe, K. K., Earle, N., Squire, I., Richards, M., … Whalley, G. A., … on behalf of the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC). (2015). Is heart rate a risk marker in patients with chronic heart failure and concomitant atrial fibrillation? Results from the MAGGIC meta-analysis. European Journal of Heart Failure, 17(11), 1182-1191. doi: 10.1002/ejhf.346
Journal - Research Article
Teh, R. O., Kerse, N. M., Robinson, E. M., Whalley, G. A., Connolly, M. J., & Doughty, R. N. (2015). Left ventricular geometry and all-cause mortality in advanced age. Heart, Lung & Circulation, 24(1), 32-39. doi: 10.1016/j.hlc.2014.06.017
Journal - Research Article
The EchoNoRMAL (Echocardiographic Normal Ranges Meta-Analysis of the Left Heart) Collaboration, including Whalley, G. A., Cameron, V., Richards, A. M., & Troughton, R. (2015). Ethnic-specific normative reference values for echocardiographic LA and LV size, LV mass, and systolic function: The EchoNoRMAL Study. JACC: Cardiovascular Imaging, 8(6), 656-665. doi: 10.1016/j.jcmg.2015.02.014
Journal - Research Article
Whalley, G. A., Pitama, S., Troughton, R. W., Doughty, R. N., Gamble, G. D., Gillies, T., Wells, J. E., Faatoese, A., Huria, T., Richards, M., & Cameron, V. A. (2015). Higher prevalence of left ventricular hypertrophy in two Māori cohorts: Findings from the Hauora Manawa/Community Heart Study. Australian & New Zealand Journal of Public Health, 39(1), 26-31. doi: 10.1111/1753-6405.12300
Journal - Research Article
Yan, M. R., Brown, D., Parsons, A., Whalley, G. A., Hamid, N., Kantono, K., … Rush, E. (2015). Branding, ingredients and nutrition information: Consumer liking of a healthier snack. Journal of Food Research, 4(5), 64-72. doi: 10.5539/jfr.v4n5p64
Journal - Research Article
Padwal, R., McAlister, F. A., McMurray, J. J. V., Cowie, M. R., Rich, M., Pocock, S., … Whalley, G., … for the Meta-analysis Global Group in Chronic Heart Failure (MAGGIC) Investigators. (2014). The obesity paradox in heart failure patients with preserved versus reduced ejection fraction: A meta-analysis of individual patient data. International Journal of Obesity, 38(8), 1110-1114. doi: 10.1038/ijo.2013.203
Journal - Research Article
Palmer, B. R., Slow, S., Ellis, K. L., Pilbrow, A. P., Skelton, L., Frampton, C. M., Palmer, S. C., Troughton, R. W., Yandle, T. G., … Whalley, G. A., … Lever, M., George, P. M., Chambers, S. T., … Richards, A. M., & Cameron, V. A. (2014). Genetic polymorphism rs6922269 in the MTHFD1L gene is associated with survival and baseline active vitamin B12 levels in post-acute coronary syndromes patients. PLoS ONE, 9(3), e89029. doi: 10.1371/journal.pone.0089029
Journal - Research Article
Pilbrow, A. P., Cordeddu, L., Cameron, V. A., Frampton, C. M., Troughton, R. W., Doughty, R. N., Whalley, G. A., … Yandle, T. G., Richards, A. M., & Foo, R. S.-Y. (2014). Circulating miR-323-3p and miR-652: Candidate markers for the presence and progression of acute coronary syndromes. International Journal of Cardiology, 176, 375-385. doi: 10.1016/j.ijcard.2014.07.068
Journal - Research Article
Poppe, K. K., Doughty, R. N., Walsh, H. J., Triggs, C. M., & Whalley, G. A. (2014). A comparison of the effects of indexation on standard echocardiographic measurements of the left heart in a healthy multi-racial population. International Journal of Cardiovascular Imaging, 30(4), 749-758. doi: 10.1007/s10554-014-0395-y
Journal - Research Article
Teh, R. O., Kerse, N. M., Robinson, E. M., Doughty, R. N., & Whalley, G. A. (2014). Which cardiovascular risk factors are associated with cardiovascular disease and predict future events in advanced age in New Zealand? Australasian Journal on Ageing, 33(1), 14-21. doi: 10.1111/j.1741-6612.2012.00626.x
Journal - Research Article
Wong, C. M., Hawkins, N. M., Petrie, M. C., Jhund, P. S., Gardner, R. S., Ariti, C. A., … Whalley, G. A., … on behalf of the MAGGIC Investigators. (2014). Heart failure in younger patients: The meta-analysis global group in chronic heart failure (MAGGIC). European Heart Journal, 35(39), 2714-2721. doi: 10.1093/eurheartj/ehu216
Journal - Research Article
Buckley, B., White, S., Poppe, K., & Whalley, G. (2013). The cardiac sonography workforce in New Zealand. Australasian Journal of Ultrasound in Medicine, 16(2), 77-85. doi: 10.1002/j.2205-0140.2013.tb00169.x
Journal - Research Article
Pocock, S. J., Ariti, C. A., McMurray, J. J. V., Maggioni, A., Køber, L., Squire, I. B., … Whalley, G. A., … on behalf of the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC). (2013). Predicting survival in heart failure: A risk score based on 39 372 patients from 30 studies. European Heart Journal, 34(19), 1404-1413. doi: 10.1093/eurheartj/ehs337
Journal - Research Article
Poppe, K. K., Squire, I. B., Whalley, G. A., Køber, L., McAlister, F. A., McMurray, J. J. V., … on behalf of the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC). (2013). Known and missing left ventricular ejection fraction and survival in patients with heart failure: A MAGGIC meta-analysis report. European Journal of Heart Failure, 15(11), 1220-1227. doi: 10.1093/eurjhf/hft101
Journal - Research Article
Stamp, L. K., Wells, J. E., Pitama, S., Faatoese, A., Doughty, R. N., Whalley, G., Richards, A. M., & Cameron, V. A. (2013). Hyperuricaemia and gout in New Zealand rural and urban Māori and non-Māori communities. Internal Medicine Journal, 43(6), 678-684. doi: 10.1111/imj.12062
Journal - Research Article
Stehlin, E., Malpas, S. C., Budgett, D. M., Barrett, C. J., McCormick, D., Whalley, G., … Guild, S.-J. (2013). Chronic measurement of left ventricular pressure in freely moving rats. Journal of Applied Physiology, 115(11), 1672-1682. doi: 10.1152/japplphysiol.00683.2013
Journal - Research Article
The Echocardiographic Normal Ranges Meta-Analysis of the Left Heart (EchoNoRMAL) Collaboration, including Whalley, G. A., Cameron, V., Richards, A. M., & Troughton, R. (2013). A meta-analysis of echocardiographic measurements of the left heart for the development of normative reference ranges in a large international cohort: The EchoNoRMAL study. European Heart Journal, 15, 341-348. doi: 10.1093/ehjci/jet240
Journal - Research Article
Whalley, G. A., Marwick, T. H., Doughty, R. N., Cooper, B. A., Johnson, D. W., Pilmore, A., … and the IDEAL Echo Substudy Investigators. (2013). Effect of early initiation of dialysis on cardiac structure and function: Results from the echo substudy of the IDEAL trial. American Journal of Kidney Diseases, 61(2), 262-270. doi: 10.1053/j.ajkd.2012.09.008
Journal - Research Article
Cameron, V. A., Faatoese, A. F., Gillies, M. W., Robertson, P. J., Huria, T. M., Doughty, R. N., Whalley, G. A., … Richards, M. A., Troughton, R. W., Tikao-Mason, K. N., Wells, E. J., Sheerin, I. G., & Pitama, S. G. (2012). A cohort study comparing cardiovascular risk factors in rural Māori, urban Māori and non-Māori communities in New Zealand. BMJ Open, 2(3), e000799. doi: 10.1136/bmjopen-2011-000799
Journal - Research Article
Carrick-Ranson, G., Doughty, R. N., Whalley, G. A., Walsh, H. J., Gamble, G. D., & Baldi, J. C. (2012). The larger exercise stroke volume in endurance-trained men does not result from increased left ventricular early or late inflow or tissue velocities. Acta Physiologica, 205(4), 520-531. doi: 10.1111/j.1748-1716.2012.02430.x
Journal - Research Article
Ellis, K. L., Palmer, B. R., Frampton, C. M., Troughton, R. W., Doughty, R. N., Whalley, G. A., … Pilbrow, A. P., Skelton, L., Yandle, T. G., Richards, A. M., & Cameron, V. A. (2012). Genetic variation in the renin-angiotensin-aldosterone system is associated with cardiovascular risk factors and early mortality in established coronary heart disease. Journal of Human Hypertension, 27, 237-244. doi: 10.1038/jhh.2012.24
Journal - Research Article
Ellis, K. L., Pilbrow, A. P., Potter, H. C., Frampton, C. M., Doughty, R. N., Whalley, G. A., … Palmer, B. R., Skelton, L., Yandle, T. G., Troughton, R. W., Richards, A. M., & Cameron, V. A. (2012). Association between endothelin type A receptor haplotypes and mortality in coronary heart disease. Personalized Medicine, 9(3), 341-349. doi: 10.2217/PME.12.10
Journal - Research Article
Ghio, S., Temporelli, P. L., Marsan, N. A., Poppe, K., Giannuzzi, P., Dini, F. L., … Whalley, G., on behalf of the MeRGE HF collaborators. (2012). Prognostic implications of left ventricular dilation in patients with nonischemic heart failure: Interactions with restrictive filling pattern and mitral regurgitation. Congestive Heart Failure, 18(4), 198-204. doi: 10.1111/j.1751-7133.2011.00281.x
Journal - Research Article
LeGrice, I. J., Pope, A. J., Sands, G. B., Whalley, G., Doughty, R. N., & Smaill, B. H. (2012). Progression of myocardial remodeling and mechanical dysfunction in the spontaneously hypertensive rat. American Journal of Physiology: Heart & Circulatory Physiology, 303(11), H1353-H1365. doi: 10.1152/ajpheart.00748.2011
Journal - Research Article
Martínez-Sellés, M., Doughty, R. N., Poppe, K., Whalley, G. A., Earle, N., Tribouilloy, C., … on behalf of the Meta-analysis Global Group in Chronic Heart Failure (MAGGIC), including Richards, A. M. (2012). Gender and survival in patients with heart failure: Interactions with diabetes and aetiology. Results from the MAGGIC individual patient meta-analysis. European Journal of Heart Failure, 14(5), 473-479. doi: 10.1093/eurjhf/hfs026
Journal - Research Article
McAlister, F. A., Ezekowitz, J., Tarantini, L., Squire, I., Komajda, M., Bayes-Genis, A., … Whalley, G., … and Meta-analysis Global Group in Chronic Heart Failure (MAGGIC) Investigators, including Richards, A. M. (2012). Renal dysfunction in patients with heart failure with preserved versus reduced ejection fraction: Impact of the new Chronic Kidney Disease-Epidemiology Collaboration Group formula. Circulation: Heart Failure, 5(3), 309-314. doi: 10.1161/CIRCHEARTFAILURE.111.966242
Journal - Research Article
Palmer, B. R., Frampton, C. M., Skelton, L., Yandle, T. G., Doughty, R. N., Whalley, G. A., … Troughton, R. W., Richards, A. M., & Cameron, V. A. (2012). KCNE5 polymorphism rs697829 is associated with QT interval and survival in acute coronary syndromes patients. Journal of Cardiovascular Electrophysiology, 23(3), 319-324. doi: 10.1111/j.1540-8167.2011.02192.x
Journal - Research Article
Poppe, K. K., Edgerton Bachmann, M., Triggs, C. M., Doughty, R. N., & Whalley, G. A. (2012). Geographic variation in left ventricular mass and mass index: A systematic review. Journal of Human Hypertension, 26(7), 420-429. doi: 10.1038/jhh.2011.56
Journal - Research Article
Rusinaru, D., Tribouilloy, C., Berry, C., Richards, A. M., Whalley, G. A., Earle, N., … on behalf of the MAGGIC Investigators. (2012). Relationship of serum sodium concentration to mortality in a wide spectrum of heart failure patients with preserved and with reduced ejection fraction: An individual patient data meta-analysis. European Journal of Heart Failure, 14(10), 1139-1146. doi: 10.1093/eurjhf/hfs099
Journal - Research Article
ADVANCE Echocardiography Substudy Investigators, ADVANCE Collaborative Group, including Troughton, R., & Whalley, G. A. (2011). Effects of perindopril-indapamide on left ventricular diastolic function and mass in patients with type 2 diabetes: The ADVANCE Echocardiography Substudy. Journal of Hypertension, 29(7), 1439-1447. doi: 10.1097/HJH.0b013e3283480fe9
Journal - Research Article
Ellis, K. L., Frampton, C. M., Pilbrow, A. P., Troughton, R. W., Doughty, R. N., Whalley, G. A., … Skelton, L., Thomson, J. A., Yandle, T. G., Richards, A. M., & Cameron, V. A. (2011). Genomic risk variants at 1p13.3, 1q41, and 3q22.3 are associated with subsequent cardiovascular outcomes in healthy controls and in established coronary artery disease. Circulation: Cardiovascular Genetics, 4(6), 636-646. doi: 10.1161/circgenetics.111.960336
Journal - Research Article
Ellis, K. L., Newton-Cheh, C., Wang, T. J., Frampton, C. M., Doughty, R. N., Whalley, G. A., … Skelton, L., Davis, N., Yandle, T. G., Troughton, R. W., Richards, A. M., & Cameron, V. A. (2011). Association of genetic variation in the natriuretic peptide system with cardiovascular outcomes. Journal of Molecular & Cellular Cardiology, 50(4), 695-701. doi: 10.1016/j.yjmcc.2011.01.010
Journal - Research Article
Faatoese, A. F., Pitama, S. G., Gillies, T. W., Robertson, P. J., Huria, T. M., Tikao-Mason, K. N., … Whalley, G. A., Richards, A. M., Troughton, R. W., Sheerin, I. G., Wells, J. E., & Cameron, V. A. (2011). Community screening for cardiovascular risk factors and levels of treatment in a rural Māori cohort. Australian & New Zealand Journal of Public Health, 35(6), 517-523. doi: 10.1111/j.1753-6405.2011.00777.x
Journal - Research Article
Meta-analysis Global Group in Chronic Heart Failure (MAGGIC), including Whalley, G. A. (2011). The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: An individual patient data meta-analysis: Meta-analysis Global Group in Chronic Heart Failure (MAGGIC). European Heart Journal, 33(14), 1750-1757. doi: 10.1093/eurheartj/ehr254
Journal - Research Article
Pitama, S., Wells, J. E., Faatoese, A., Tikao-Mason, K., Robertson, P., Huria, T., Gillies, T., … Whalley, G., Troughton, R., Sheerin, I., Richards, M., & Cameron, V. A. (2011). A Kaupapa Māori approach to a community cohort study of heart disease in New Zealand. Australian & New Zealand Journal of Public Health, 35(3), 249-255. doi: 10.1111/j.1753-6405.2011.00702.x
Journal - Research Article
Poppe, K. K., Doughty, R. N., Yu, C.-M., Quintana, M., Møller, J. E., Klein, A. L., … Whalley, G. A., on behalf of the MeRGE Collaborators. (2011). Understanding differences in results from literature-based and individual patient meta-analyses: An example from meta-analyses of observational data. International Journal of Cardiology, 148, 209-213. doi: 10.1016/j.ijcard.2009.09.566
Journal - Research Article
Poppe, K. K., Whalley, G. A., Somaratne, J. B., Keelan, S., Bagg, W., Triggs, C. M., & Doughty, R. N. (2011). Role of echocardiographic left ventricular mass and carotid intima-media thickness in the cardiovascular risk assessment of asymptomatic patients with type 2 diabetes mellitus. Internal Medicine Journal, 41(5), 391-398. doi: 10.1111/j.1445-5994.2010.02305.x
Journal - Research Article
Somaratne, J. B., Whalley, G. A., Poppe, K. K., ter Bals, M. M., Wadams, G., Pearl, A., … Doughty, R. N. (2011). Screening for left ventricular hypertrophy in patients with type 2 diabetes mellitus in the community. Cardiovascular Diabetology, 10, 29. doi: 10.1186/1475-2840-10-29
Journal - Research Article
Ellis, K. L., Pilbrow, A. P., Frampton, C. M., Doughty, R. N., Whalley, G. A., Ellis, C. J., Palmer, B. R., Skelton, L., Yandle, T. G., Palmer, S. C., Troughton, R. W., Richards, A. M., & Cameron, V. A. (2010). A common variant at chromosome 9P21.3 is associated with age of onset of coronary disease but not subsequent mortality. Circulation: Cardiovascular Genetics, 3(3), 286-293. doi: 10.1161/circgenetics.109.917443
Journal - Research Article
Hotu, C., Bagg, W., Collins, J., Harwood, L., Whalley, G., Doughty, R., … on behalf of the DEFEND investigators. (2010). A community-based model of care improves blood pressure control and delays progression of proteinuria, left ventricular hypertrophy and diastolic dysfunction in Māori and Pacific patients with type 2 diabetes and chronic kidney disease: A randomized controlled trialC. Nephrology Dialysis Transplantation, 25, 3260-3266. doi: 10.1093/ndt/gfq168
Journal - Research Article
Jarvis, M. D., Palmer, B. R., Pilbrow, A. P., Ellis, K. L., Frampton, C. M., Skelton, L., … Whalley, G. A., … Yandle, T. G., Richards, A. M., & Cameron, V. A. (2010). CYP1A1 MSPI (T6235C) gene polymorphism is associated with mortality in acute coronary syndrome patients. Clinical & Experimental Pharmacology & Physiology, 37(2), 193-198. doi: 10.1111/j.1440-1681.2009.05261.x
Journal - Research Article
Poppe, K. K., Whalley, G. A., Richards, A. M., Wright, S. P., Triggs, C. M., & Doughty, R. N. (2010). Prediction of ACC/AHA stage B heart failure by clinical and neurohormonal profiling among patients in the community. Journal of Cardiac Failure, 16(12), 957-963. doi: 10.1016/j.cardfail.2010.07.247
Journal - Research Article
Stewart, R. A. H., Kerr, A. J., Whalley, G. A., Legget, M. E., Zeng, I., Williams, M. J. A., Lainchbury, J., … Richards, M. A., … for the New Zealand Heart Valve Study Investigators. (2010). Left ventricular systolic and diastolic function assessed by tissue Doppler imaging and outcome in asymptomatic aortic stenosis. European Heart Journal, 31(18), 2216-2222. doi: 10.1093/eurheartj/ehq159
Journal - Research Article
Wasywich, C. A., Gamble, G. D., Whalley, G. A., & Doughty, R. N. (2010). Understanding changing patterns of survival and hospitalization for heart failure over two decades in New Zealand: Utility of 'days alive and out of hospital' from epidemiological data. European Journal of Heart Failure, 12, 462-468. doi: 10.1093/eurjhf/hfq027
Journal - Research Article
Wasywich, C. A., Pope, A. J., Somaratne, J., Poppe, K. K., Whalley, G. A., & Doughty, R. N. (2010). Atrial fibrillation and the risk of death in patients with heart failure: A literature-based meta-analysis. Internal Medicine Journal, 40, 347-356. doi: 10.1111/j.1445-5994.2009.01991.x
Journal - Research Article
Dini, F. L., Whalley, G., Poppe, K., Fontanive, P., Rosa, G. M., Doughty, R. N., & Di Bello, V. (2009). Plasma N‐terminal protype‐B natriuretic peptide and restrictive mitral flow to risk‐stratify patients with stage B heart failure. Clinical Cardiology, 32(12), 711-717. doi: 10.1002/clc.20617
Journal - Research Article
Rossi, A., Temporelli, P. L., Quintana, M., Dini, F. L., Ghio, S., Hillis, G. S., … Whalley, G. A., on behalf of the MeRGE Heart Failure Collaborators, including Frampton, C. M., & Troughton, R. (2009). Independent relationship of left artial size and mortality in patients with heart failure: An individual patient meta-analysis of longitudinal data (MeRGE Heart Failure). European Journal of Heart Failure, 11, 929-936. doi: 10.1093/eurjhf/hfp112
Journal - Research Article
Somaratne, J. B., Berry, C., McMurray, J. J. V., Poppe, K. K., Doughty, R. N., & Whalley, G. A. (2009). The prognostic significance of heart failure with preserved left ventricular ejection fraction: A literature-based meta-analysis. European Journal of Heart Failure, 11, 855-962. doi: 10.1093/eurjhf/hfp103
Journal - Research Article
Wasywich, C. A., Whalley, G. A., Walsh, H. A., Gamble, G. D., & Doughty, R. N. (2009). Changes in tissue-doppler echocardiographic assessment of left ventricular filling during NT-proBNP guided heart failure treatment titration: A pilot study. Heart, Lung & Circulation, 18(1), 38-44. doi: 10.1016/j.hlc.2008.07.002
Journal - Research Article
Whalley, G. A., Gusso, S., Hofman, P., Cutfield, W., Poppe, K. K., Doughty, R. N., & Baldi, J. C. (2009). Structural and functional cardiac abnormalities in adolescent girls with poorly controlled type 2 diabetes. Diabetes Care, 32(5), 883-888. doi: 10.2337/dc08-2005
Journal - Research Article
Bridgman, P. G., Ashrafi, A. N., Mann, S., Whalley, G. A., on behalf of the SCANZ collaborators. (2008). Survey of clinical echocardiography in New Zealand (SCANZ). New Zealand Medical Journal, 121(1269). Retrieved from http://journal.nzma.org.nz/journal/121-1269/2924/content.pdf
Journal - Research Article
Kerr, A. J., Raffel, O. C., Whalley, G. A., Zeng, I., & Stewart, R. A. (2008). Elevated B-type natriuretic peptide despite normal left ventricular function on rest and exercise stress echocardiography in mitral regurgitation. European Heart Journal, 29(3), 363-370. doi: 10.1093/eurheartj/ehm553
Journal - Research Article
Meta-Analysis Research Group in Echocardiography (MeRGE) AMI Collaborators, including Whalley, G. A. (2008). Independent prognostic importance of a restrictive left ventricular filling pattern after myocardial infarction: An individual patient meta-analysis: Meta-analysis research group in echocardiography acute myocardial infarction. Circulation, 117, 2591-2598. doi: 10.1161/circulationaha.107.738625
Journal - Research Article
Meta-analysis Research Group in Echocardiography (MeRGE) Heart Failure Collaborators, including Whalley, G. A. (2008). Independence of restrictive filling pattern and LV ejection fraction with mortality in heart failure: An individual patient meta-analysis. European Journal of Heart Failure, 10, 786-792. doi: 10.1016/j.ejheart.2008.06.005
Journal - Research Article
Palmer, B. R., Jarvis, M. D., Pilbrow, A. P., Ellis, K. L., Frampton, C. M., Skelton, L., Yandle, T. G., … Whalley, G. A., … Troughton, R. W., Richards, A. M., & Cameron, V. A. (2008). Angiotensin-converting enzyme 2 A1075G polymorphism is associated with survival in an acute coronary syndromes cohort. American Heart Journal, 156(4), 752-758. doi: 10.1016/j.ahj.2008.06.013
Journal - Research Article
Stewart, R. A., Kerr, A. J., Cowan, B. R., Young, A. A., Occleshaw, C., Richards, A. M., … Whalley, G. A., … for the ZEST Study Investigators. (2008). A randomized trial of the aldosterone-receptor antagonist eplerenone in asymptomatic moderate-severe aortic stenosis. American Heart Journal, 156, 348-355. doi: 10.1016/j.ahj.2008.03.012
Journal - Research Article
van Pelt, N. C., Kerr, A. J., Legget, M. E., Pasupati, S., Whalley, G., Wong, S., … Stewart, R. A. H. (2008). Increased B-type natriuretic peptide is associated with an abnormal blood pressure response to exercise in asymptomatic aortic stenosis. International Journal of Cardiology, 127(3), 313-320. doi: 10.1016/j.ijcard.2007.07.172
Journal - Research Article
Whalley, G. A., Wright, S. P., Pearl, A., Gamble, G. D., Walsh, H. J., Richards, M., & Doughty, R. N. (2008). Prognostic role of echocardiography and brain natriuretic peptide in symptomatic breathless patients in the community. European Heart Journal, 29(4), 509-516. doi: 10.1093/eurheartj/ehm647
Journal - Research Article
Astley, C. M., Portelli, L., Whalley, G. A., & Davidson, P. M. (2007). Coming of age: Affiliate member profile and participation in the Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand. Heart, Lung & Circulation, 16(6), 447-451. doi: 10.1016/j.hlc.2007.02.088
Journal - Research Article
Bruch, C., Reinecke, H., Scheld, H. H., Whalley, G. A., Stypmann, J., Breithardt, G., … Gradaus, R. (2007). Transmitral flow patterns and the presence of chronic kidney disease provide independent and incremental prognostic information in patients with heart failure and systolic dysfunction. Journal of the American Society of Echocardiography, 20(8), 989-997. doi: 10.1016/j.echo.2007.01.013
Journal - Research Article
Somaratne, J. B., Whalley, G. A., Gamble, G. D., & Doughty, R. N. (2007). Restrictive filling pattern is a powerful predictor of heart failure events postacute myocardial infarction and in established heart failure: A literature-based meta-analysis. Journal of Cardiac Failure, 13(5), 346-352. doi: 10.1016/j.cardfail.2007.01.010
Journal - Research Article
van Pelt, N., Stewart, R. A. H., Legget, M. E., Whalley, G. A., Wong, S. P., Zeng, I., … Kerr, A. J. (2007). Longitudinal left ventricular contractile dysfunction after exercise in aortic stenosis. Heart, 93(6), 732-738. doi: 10.1136/hrt.2006.100164
Journal - Research Article
Whalley, G. A., Gamble, G. D., & Doughty, R. N. (2007). The prognostic significance of restrictive diastolic filling associated with heart failure: A meta-analysis. International Journal of Cardiology, 116(1), 70-77. doi: 10.1016/j.ijcard.2006.03.032
Journal - Research Article
Whalley, G. A., Gamble, G. D., Dini, F. L., Klein, A. L., Møller, J. E., Quintana, M., … on behalf of the Meta-Analysis Research Group in Echocardiography (MeRGE) Collaborators. (2007). Individual patient meta-analyses of restrictive diastolic filling pattern and mortality in patients post acute myocardial infarction and in patients with chronic heart failure. International Journal of Cardiology, 122, 207-215. doi: 10.1016/j.ijcard.2006.11.080
Journal - Research Article
Bagg, W., Aoina, J., Cross, P. A. R., Whalley, G. A., Gamble, G. D., Doughty, R. N., & Holdaway, I. M. (2006). Serum IGF-I levels are similar in Samoan, Māori and European populations despite differences in body composition. Growth Hormone & IGF Research, 16, 57-60. doi: 10.1016/j.ghir.2005.11.002
Journal - Research Article
Baldi, J. C., Aoina, J. L., Whalley, G. A., Carrick-Ranson, G., Walsh, H., O'Shaughnessy, H., … Doughty, R. N. (2006). The effect of type 2 diabetes on diastolic function. Medicine & Science in Sports & Exercise, 38(8), 1384-1388. doi: 10.1249/01.mss.0000228954.90591.95
Journal - Research Article
Wasywich, C. A., Whalley, G. A., Gamble, G. D., Wright, S. P., & Doughty, R. N. (2006). Does rhythm matter? The prognostic importance of atrial fibrillation in heart failure. Heart, Lung & Circulation, 15(6), 353-357. doi: 10.1016/j.hlc.2006.07.011
Journal - Research Article
Whalley, G. A., Gamble, G. D., & Doughty, R. N. (2006). Restrictive diastolic filling predicts death after acute myocardial infarction: Systematic review and meta-analysis of prospective studies. Heart, 92(11), 1588-1594. doi: 10.1136/hrt.2005.083055
Journal - Research Article
Whalley, G. A., Gamble, G. D., Walsh, H. J., Sharpe, N., & Doughty, R. N. (2005). Quantitative evaluation of regional endocardial visualisation with second harmonic imaging and contrast left ventricular opacification in heart failure patients. European Journal of Echocardiography, 6, 134-143. doi: 10.1016/j.euje.2004.08.003
Journal - Research Article