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Contact Details

Email
chihiro.hasegawa@otago.ac.nz
Position
Honorary Senior Lecturer
Qualifications
MSc PhD
Research summary
Pharmacometrics
Memberships
International Society of Pharmacometrics

Research

My research mainly involves the automated scale reduction of quantitative systems pharmacology (QSP) models for data-driven population modelling.

Publications

Sharif, S., Hasegawa, C., Fidler, M., & Duffull, S. B. (2024). Exploring the performance of the optimized Inductive Linearization solver for simulation of the Van der Pol oscillator (a stiff non-linear system). Nonlinear Analysis & Differential Equations, 12(1), 17-31. doi: 10.12988/nade.2024.91253 Journal - Research Article

Sharif, S., Hasegawa, C., & Duffull, S. B. (2022). Exploring Inductive Linearization for simulation and estimation with an application to the Michaelis-Menten model. Journal of Pharmacokinetics & Pharmacodynamics, 49, 445-453. doi: 10.1007/s10928-022-09813-z Journal - Research Article

Derbalah, A., Al-Sallami, H., Hasegawa, C., Gulati, A., & Duffull, S. B. (2022). A framework for simplification of quantitative systems pharmacology models in clinical pharmacology. British Journal of Clinical Pharmacology, 88, 1430-1440. doi: 10.1111/bcp.14451 Journal - Research Other

Ooi, Q. X., Hasegawa, C., Duffull, S. B., & Wright, D. F. B. (2020). Kinetic-pharmacodynamic model for drugs with non-linear elimination: Parameterisation matters. British Journal of Clinical Pharmacology, 86(2), 196-198. doi: 10.1111/bcp.14154 Journal - Research Other

Hasegawa, C., & Duffull, S. B. (2019). Reusing smaller versions of large models: A case example of reuse of a simplified bone model. Clinical Pharmacology & Therapeutics, 106(6), 1184-1186. doi: 10.1002/cpt.1582 Journal - Research Other

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