Dr Kyle Perrin

2020

Journal - Research Article

Brown, S. G. A., Ball, E. L., Perrin, K., Asha, S., Braithwaite, I., Egerton-Warburton, D., … Weatherall, M., Beasley, R., for the PSP Investigators, including Beckert, L., & Hancox, R. J. (2020). Conservative versus interventional treatment for spontaneous pneumothorax. New England Journal of Medicine, 382, 405-415. doi: 10.1056/NEJMoa1910775

2016

Journal - Research Article

Jefferies, S., Braithwaite, I., Walker, S., Weatherall, M., Jennings, L., Luck, M., … Siebers, R., Blackmore, T., Beasley, R., Perrin, K., on behalf of the Pi Study Group. (2016). Randomized controlled trial of the effect of regular paracetamol on influenza infection. Respirology, 21(2), 370-377. doi: 10.1111/resp.12685

Journal - Research Other

Brown, S. G. A., Ball, E. L., Perrin, K., Read, C. A., Asha, S. A., Beasley, R., … the PSP Study Group, including Beckert, L., & Hancox, R. J. (2016). Study protocol for a randomised controlled trial of invasive versus conservative management of primary spontaneous pneumothorax. BMJ Open, 6, e011826. doi: 10.1136/bmjopen-2016-011826

Journal - Professional & Other Non-Research Articles

Beasley, R., Hancox, R. J., Harwood, M., Perrin, K., Poot, B., Pilcher, J., Reid, J., … Thayabaran, D. (2016). Asthma and Respiratory Foundation NZ Adult Asthma Guidelines: A quick reference guide. New Zealand Medical Journal, 129(1445), 83-102. Retrieved from http://www.nzma.org.nz/journal

2015

Journal - Research Article

Pilcher, J., Weatherall, M., Perrin, K., & Beasley, R. (2015). Oxygen therapy in acute exacerbations of chronic obstructive pulmonary disease. Expert Review of Respiratory Medicine, 9(3), 287-293. doi: 10.1586/17476348.2015.1016503

Ioannides, S. J., Siebers, R., Perrin, K., Weatherall, M., Crane, J., Travers, J., Shirtcliffe, P., & Beasley, R. (2015). The effect of 1 g of acetaminophen twice daily for 12 weeks on alanine transaminase levels: A randomized placebo-controlled trial. Clinical Biochemistry, 48, 713-715. doi: 10.1016/j.clinbiochem.2015.04.011

Pilcher, J., Cameron, L., Braithwaite, I., Bowles, D., Swain, A., Bailey, M., Weatherall, M., Beasley, R., & Perrin, K. (2015). Comparative audit of oxygen use in the prehospital setting in acute COPD exacerbation over 5 years. Emergency Medicine Journal, 32, 234-238. doi: 10.1136/emermed-2013-203094

2014

Journal - Research Article

Bowles, D., & Perrin, K. (2014). A retrospective case series of 44 patients with community-acquired Staphylococcus aureus pneumonia. New Zealand Medical Journal, 127(1391). Retrieved from http://www.nzma.org.nz/journal

Ioannides, S. J., Williams, M., Jefferies, S., Perrin, K., Weatherall, M., Siebers, R., Crane, J., Patel, M., … Shirtcliffe, P., & Beasley, R. (2014). Randomised placebo-controlled study of the effect of paracetamol on asthma severity in adults. BMJ Open, 4(2), e004324. doi: 10.1136/bmjopen-2013-004324

Conference Contribution - Published proceedings: Abstract

Perrin, K., Jefferies, S., Braithwaite, I., Walker, S., Weatherall, M., Jennings, L., Blackmore, T., & Beasley, R. (2014). BA randomized controlled trial of the effect of regular paracetamol on influenza infection. Respirology, 19(Suppl. 2), (pp. 127). doi: 10.1111/resp.12263_8

2013

Journal - Research Article

Patel, M., Perrin, K., Pritchard, A., Williams, M., Wijesinghe, M., Weatherall, M., & Beasley, R. (2013). Accuracy of patient self-report as a measure of inhaled asthma medication use. Respirology, 18(3), 546-552. doi: 10.1111/resp.12059

Patel, M., Pilcher, J., Pritchard, A., Perrin, K., Travers, J., Shaw, D., … Weatherall, M., Beasley, R., for the SMART Study Group. (2013). Efficacy and safety of maintenance and reliever combination budesonide–formoterol inhaler in patients with asthma at risk of severe exacerbations: A randomised controlled trial. Lancet Respiratory Medicine, 1(1), 32-42. doi: 10.1016/S2213-2600(13)70007-9

Patel, M., Pilcher, J., Travers, J., Perrin, K., Shaw, D., Black, P., Weatherall, M., & Beasley, R. (2013). Use of metered-dose inhaler electronic monitoring in a real-world asthma randomized controlled trial. Journal of Allergy & Clinical Immunology: In Practice, 1(1), 83-91. doi: 10.1016/j.jaip.2012.08.004

Journal - Research Other

Fingleton, J., Sheahan, D., Cave, N., Brinded, A., Weatherall, M., Perrin, K., & Beasley, R. (2013). Topical kanuka honey for the treatment of rosacea. Focus on Alternative & Complementary Therapies, 18(4), 221-222. doi: 10.1111/fct.12057

Conference Contribution - Verbal presentation and other Conference outputs

Perrin, K. (2013, August). Oxygen: A new look at an old therapy. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2012

Journal - Research Article

Cameron, L., Pilcher, J., Weatherall, M., Beasley, R., & Perrin, K. (2012). The risk of serious adverse outcomes associated with hypoxaemia and hyperoxaemia in acute exacerbations of COPD. Postgraduate Medical Journal, 88(1046), 684-689. doi: 10.1136/postgradmedj-2012-130809

Edwards, L., Perrin, K., Williams, M., Weatherall, M., & Beasley, R. (2012). Randomised controlled crossover trial of the effect on PtCO₂ of oxygen-driven versus air-driven nebulisers in severe chronic obstructive pulmonary disease. Emergency Medicine Journal, 29(11), 894-898. doi: 10.1136/emermed-2011-200443

Eyers, S., Fingleton, J., Perrin, K., & Beasley, R. (2012). Proposed MHRA changes to UK children's paracetamol dosing recommendations: Modelling study. Journal of the Royal Society of Medicine, 105(6), 263-269. doi: 10.1258/jrsm.2012.110330

Wijesinghe, M., Perrin, K., Healy, B., Weatherall, M., & Beasley, R. (2012). Randomized controlled trial of high concentration oxygen in suspected community-acquired pneumonia. Journal of the Royal Society of Medicine, 105(5), 208-216. doi: 10.1258/jrsm.2012.110084

Eyers, S., Fingleton, J., Eastwood, A., Perrin, K., & Beasley, R. (2012). British National Formulary for Children: The risk of inappropriate paracetamol prescribing. Archives of Disease in Childhood, 97(3), 279-282. doi: 10.1136/archdischild-2011-300464

Ranchord, A. M., Argyle, R., Beynon, R., Perrin, K., Sharma, V., Weatherall, M., Simmonds, M., … Beasley, R. (2012). High-concentration versus titrated oxygen therapy in ST-elevation myocardial infarction: A pilot randomized controlled trial. American Heart Journal, 163(2), 168-175. doi: 10.1016/j.ahj.2011.10.013

Ranchord, A. M., Perrin, K., Weatherall, M., Beasley, R., & Simmonds, M. (2012). A randomised controlled trial of the effect of high concentration oxygen on myocardial ischaemia during exercise. International Journal of Cardiology, 160(3), 201-205. doi: 10.1016/j.ijcard.2011.04.017

Conference Contribution - Published proceedings: Abstract

Eyers, S., Eastwood, A., Perrin, K., Weatherall, M., & Beasley, R. (2012). Quality of paracetamol prescribing at Wellington Regional Hospital: A clinical audit. Internal Medicine Journal, 42(Suppl. s2), (pp. 15). doi: 10.1111/j.1445-5994.2012.02780.x

2011

Journal - Research Article

Jefferies, S., Weatherall, M., Young, P., Eyers, S., Perrin, K. G., & Beasley, C. R. W. (2011). The effect of antipyretic medications on mortality in critically ill patients with infection: A systematic review and meta-analysis. Critical Care & Resuscitation, 13(2), 125-131.

Perrin, K., Wijesinghe, M., Healy, B., Wadsworth, K., Bowditch, R., Bibby, S., … Weatherall, M., & Beasley, R. (2011). Randomised controlled trial of high concentration versus titrated oxygen therapy in severe exacerbations of asthma. Thorax, 66, 937-941. doi: 10.1136/thx.2010.155259

Wijesinghe, M., Perrin, K., Healy, B., Hart, K., Clay, J., Weatherall, M., & Beasley, R. (2011). Pre-hospital oxygen therapy in acute exacerbations of chronic obstructive pulmonary disease. Internal Medicine Journal, 41(8), 618-622. doi: 10.1111/j.1445-5994.2010.02207.x

Perrin, K., Wijesinghe, M., Weatherall, M., & Beasley, R. (2011). Assessing PaCO₂ in acute respiratory disease: Accuracy of a transcutaneous carbon dioxide device. Internal Medicine Journal, 41(8), 630-633. doi: 10.1111/j.1445-5994.2010.02213.x

Charles, T., Mackintosh, D., Healy, B., Perrin, K., Weatherall, M., & Beasley, R. (2011). Merino wool graduated compression stocking increases lower limb venous blood flow: A randomized controlled trial. Advances in Therapy, 28(3), 227-237. doi: 10.1007/s12325-010-0107-5

Wijesinghe, M., Williams, M., Perrin, K., Weatherall, M., & Beasley, R. (2011). The effect of supplemental oxygen on hypercapnia in subjects with obesity-associated hypoventilation: A randomized, crossover, clinical study. Chest, 139(5), 1018-1024. doi: 10.1378/chest.10-1280

Edwards, L., Perrin, K., Wijesinghe, M., Weatherall, M., Beasley, R., & Travers, J. (2011). The value of the CRB65 score to predict mortality in exacerbations of COPD requiring hospital admission. Respirology, 16(4), 625-629. doi: 10.1111/j.1440-1843.2011.01926.x

Jefferies, S., Earl, D., Berry, N., Blackmore, T., Rooker, S., Raymond, N., … Weatherall, M., Beasley, R., & Perrin, K. (2011). Effectiveness of the 2009 seasonal influenza vaccine against pandemic influenza A(H1N1)2009 in healthcare workers in New Zealand, June-August 2009. Eurosurveillance, 16(2), 19761. Retrieved from http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19761

Journal - Research Other

Perrin, K. (2011). Potential dangers of chest drains: Response to case report by Drs Jayathissa and Dee [Letter]. New Zealand Medical Journal, 124(1344). Retrieved from http://journal.nzma.org.nz/journal/124-1344/4921/content.pdf

Eyers, S., Jefferies, S., Shirtcliffe, P., Perrin, K., & Beasley, R. (2011). Antipyretic therapy for influenza infection: Benefit or harm? [Letter]. New Zealand Medical Journal, 124(1338). Retrieved from http://journal.nzma.org.nz/journal/124-1338/4773/content.pdf

Patel, M., Perrin, K., & Beasley, R. (2011). Beta agonist use during asthma exacerbations: How much is too much? [Clinical correspondence]. New Zealand Medical Journal, 124(1332). Retrieved from http://journal.nzma.org.nz/journal/124-1332/4608/content.pdf

2010

Journal - Research Article

Healy, B., Levin, E., Perrin, K., Weatherall, M., & Beasley, R. (2010). Prolonged work- and computer-related seated immobility and risk of venous thromboembolism. Journal of the Royal Society of Medicine, 103(11), 447-454. doi: 10.1258/jrsm.2010.100155

Eyers, S., Weatherall, M., Shirtcliffe, P., Perrin, K., & Beasley, R. (2010). The effect on mortality of antipyretics in the treatment of influenza infection: Systematic review and meta-analyis. Journal of the Royal Society of Medicine, 103(10), 403-411. doi: 10.1258/jrsm.2010.090441

Perrin, K., Williams, M., Wijesinghe, M., James, K., Weatherall, M., & Beasley, R. (2010). Randomized controlled trial of adherence with single or combination inhaled corticosteroid/long-acting β-agonist inhaler therapy in asthma. Journal of Allergy & Clinical Immunology, 126(3), 505-510. doi: 10.1016/j.jaci.2010.06.033

Weatherall, M., Wijesinghe, M., Perrin, K., & Beasley, R. (2010). Long-acting beta-agonists and asthma death: How useful are different study designs to evaluate the potential association? Journal of Asthma, 47(4), 434-438. doi: 10.3109/02770900903556439

Wijesinghe, M., Shirtcliffe, P., Perrin, K., Healy, B., James, K., Weatherall, M., & Beasley, R. (2010). An audit of the effect of oxygen prescription charts on clinical practice. Postgraduate Medical Journal, 86(1012), 89-93. doi: 10.1136/pgmj.2009.087528

Weatherall, M., Wijesinghe, M., Perrin, K., Harwood, M., & Beasley, R. (2010). Meta-analysis of the risk of mortality with salmeterol and the effect of concomitant inhaled corticosteroid therapy. Thorax, 65(1), 39-43. doi: 10.1136/thx.2009.116608

Journal - Research Other

Beasley, R., Perrin, K., Weatherall, M., & Wijesinghe, M. (2010). Call for withdrawal of laba single-therapy inhaler in asthma [Comment]. Lancet, 376(9743), 750-751. doi: 10.1016/S0140-6736(10)61158-0

Conference Contribution - Published proceedings: Abstract

Perrin, K. (2010). Medication in COPD and asthma. Respiratory Educators Conference: Cough, Cough, Coughing: All Ages, Many Causes. Retrieved from http://www.asthmanz.co.nz/presentations_2010.php

Perrin, K. (2010). BTS oxygen guidelines. Respiratory Educators Conference: Cough, Cough, Coughing: All Ages, Many Causes. Retrieved from http://www.asthmanz.co.nz/presentations_2010.php

Perrin, K. (2010). Investigation and treatment of chronic cough in adults. Respiratory Educators Conference: Cough, Cough, Coughing: All Ages, Many Causes. Retrieved from http://www.asthmanz.co.nz/presentations_2010.php

Conference Contribution - Verbal presentation and other Conference outputs

Perrin, K. (2010, September). BTS oxygen guidelines. Plenary presentation at the Respiratory Educators Conference: Cough Cough Coughing: All Ages, Many Causes, Wellington, New Zealand.

Perrin, K. (2010, September). Investigation and treatment of chronic cough in adults. Plenary presentation at the Respiratory Educators Conference: Cough Cough Coughing: All Ages, Many Causes, Wellington, New Zealand.

2009

Journal - Research Article

Wijesinghe, M., Weatherall, M., Perrin, K., Harwood, M., & Beasley, R. (2009). Risk of mortality associated with formoterol: A systematic review and meta-analysis. European Respiratory Journal, 34(4), 803-811. doi: 10.1183/09031936.00159708

Weatherall, M., Clay, J., James, K., Perrin, K., Shirtcliffe, P., & Beasley, R. (2009). Dose-response relationship of inhaled corticosteroids and cataracts: A systematic review and meta-analysis. Respirology, 14(7), 983-990. doi: 10.1111/j.1440-1843.2009.01589.x

Wijesinghe, M., Weatherall, M., Perrin, K., & Beasley, R. (2009). Honey in the treatment of burns: A systematic review and meta-analysis of its efficacy [Review article]. New Zealand Medical Journal, 122(1295). Retrieved from http://journal.nzma.org.nz/journal/122-1295/3610/content.pdf

Wijesinghe, M., Weatherall, M., Perrin, K., Crane, J., & Beasley, R. (2009). International trends in asthma mortality rates in the 5- to 34-year age group: A call for closer surveillance. Chest, 135(4), 1045-1049. doi: 10.1378/chest.08-2082

Wijesinghe, M., Perrin, K., Ranchord, A., Simmonds, M., Weatherall, M., & Beasley, R. (2009). Routine use of oxygen in the treatment of myocardial infarction: Systematic review. Heart, 95(3), 198-202. doi: 10.1136/hrt.2008.148742

Conference Contribution - Published proceedings: Abstract

Perrin, K., Wijesinghe, M., Weatherall, M., & Beasley, R. (2009). High concentration oxygen causes carbon dioxide retention in severe asthma: A randomised controlled trial. Thorax, 64(Suppl. 4), (pp. A72). [Abstract]

Perrin, K., Wijesinghe, M., Healy, B., Weatherall, M., & Beasley, R. (2009). Oxygen therapy in acute exacerbations of COPD. Thorax, 64(Suppl. 4), (pp. A119). doi: 10.1136/thx.2009.127167

Weatherall, M., Wijesinghe, M., Perrin, K., & Beasley, R. (2009). Statistical power of different approaches to evaluate the risk of rare severe adverse events for a new drug therapy. Proceedings of the 30th Annual Conference of the International Society for Clinical Biostatistics. (pp. 167). ISCB. Retrieved from http://www.iscb2009.info/RSystem/Soubory/ISCB09_Prog_AbsBook_web.pdf

2008

Journal - Research Article

Aldington, S., Pritchard, A., Perrin, K., James, K., Wijesinghe, M., & Beasley, R. (2008). Prolonged seated immobility at work is a common risk factor for venous thromboembolism leading to hospital admission. Internal Medicine Journal, 38, 133-135. doi: 10.1111/j.1445-5994.2007.01597.x

Journal - Research Other

Wijesinghe, M., Perrin, K., Harwood, M., Weatherall, M., & Beasley, R. (2008). The risk of asthma mortality with inhaled long acting β-agonists [Review]. Postgraduate Medical Journal, 84, 467-472. doi: 10.1136/pgmj.2007.067165