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Contact Details

Phone
+64 3 479 7169
Email
cushla.mckinney@otago.ac.nz
Position
Research Fellow
Department
Department of Pathology (Dunedin)
Qualifications
PhD MBHL
Research summary
p53 isoforms, cancer and drug resistance
Memberships
CRISPR Hub co-convenor

Research

I have a background in molecular biology and genetics, with twenty years of research experience. My initial research involved the genetics of complex diseases, with a focus on RA and gout. Most recently I have been using CRISPR / Cas9 and Nanopore technology to study genes involved in cancer development and the development of drug resistance.

Additional details

I have a strong interest in the ethical and legal issues surrounding new technologies and, in addition to my PhD in Biochemistry I also hold a Master’s degree in Bioethics and Health Law. Outside of my professional roles I am a member of the Council of the Friends of the Otago Museum, and a book reviewer for the ODT and Landfall on line.

Publications

McKinney, C. (2021). Mental capacity in anorexia nervosa. In P. Westmorland (Ed.), Tipping the scales: Ethical and legal dilemmas in managing severe eating disorders. (pp. 55-74). Washington, DC: American Psychiatric Association. Chapter in Book - Research

Mehta, S., Algie, M., Al-Jabry, T., McKinney, C., Kannan, S., Verma, C. S., … Parker, K., Henderson, L., Gould, M. L., Bhatia, P., Harfoot, R., … Kleffmann, T., … Woolley, A. G., … Braithwaite, A. (2020). Critical role for cold shock protein YB-1 in cytokinesis. Cancers, 12, 2473. doi: 10.3390/cancers12092473 Journal - Research Article

Eiholzer, R. A., Mehta, S., Kazantseva, M., Drummond, C. J., McKinney, C., Young, K., … Fleming, N., Morrin, H. R., Reader, K., Royds, J. A., Landmann, M., Petrich, S., … Taha, A., Hung, N. A., Slatter, T. L., & Braithwaite, A. W. (2020). Intronic TP53 polymorphisms are associated with increased Δ133TP53 transcript, immune infiltration and cancer risk. Cancers, 12(9), 2472. doi: 10.3390/cancers12092472 Journal - Research Article

Mehta, S., McKinney, C., Algie, M., Verma, C. S., Kannan, S., Harfoot, R., … Gould, M. L., Parker, K., … Cunliffe, H. E., … Kleffmann, T., Braithwaite, A. W., & Woolley, A. G. (2020). Dephosphorylation of YB-1 is required for nuclear localisation during G2 phase of the cell cycle. Cancers, 12(2), 315. doi: 10.3390/cancers12020315 Journal - Research Article

Ray, S., McKinney, C., Roth, L., Heinzel, S., Hodgkin, P., Mehta, S., Slatter, T. L., & Braithwaite, A. W. (2018, August). p53 does not cause growth arrest or death in normal B cells but only affects division rate. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)

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