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Contact Details

Phone
64 3 474 0999 ext 58079
Email
michael.williams@otago.ac.nz
Position
Clinical Professor
Department
Department of Medicine (Dunedin)
Qualifications
MD FRACP FACC
Research summary
Cardiology
Teaching
Integration of cardiac investigations into clinical practice.
Clinical
  • Echocardiography.
  • Interventional cardiology.
  • General cardiology.

Research

Michael Williams' research interests include studying the effect of lifestyle factors and diet on arterial function and the development of arterial disease. He has investigated the influence of physical fitness on measures of arterial inflammation and the risk of developing chest pain and heart attack in later life. His other clinical research has focussed on understanding the biology of restenosis in stents inserted in patients' heart arteries to open blockages. Studies of cardiovascular genetics have contributed to international collaborative research and the identification of novel genetic markers of arterial disease. Michael's current investigations include the regulation of gene expression on the development of narrowing and stiffening of cardiac valves with the aim of developing therapies to delay or prevent the requirement for surgical valve replacement. He is presently Chair of the Medicine Department Peer Review Committee.

Publications

Moore, M. K., Jones, G. T., McCormick, S., Williams, M. J. A., & Coffey, S. (2024). Association between lipoprotein(a), LPA genetic risk score, aortic valve disease, and subsequent major adverse cardiovascular events. European Journal of Preventive Cardiology. Advance online publication. doi: 10.1093/eurjpc/zwae100 Journal - Research Article

Moore, M. K., Jones, G. T., Whalley, G., Prendergast, B., Williams, M. J. A., & Coffey, S. (2023). Outcomes of patients with early calcific aortic valve disease detected by clinically indicated echocardiography. European Heart Journal: Cardiovascular Imaging. Advance online publication. doi: 10.1093/ehjci/jead259 Journal - Research Article

Roxburgh, B. H., Campbell, H. A., Cotter, J. D., Reymann, U., Williams, M. J. A., Gwynne-Jones, D., & Thomas, K. N. (2023). Upper-limb high-intensity interval training or passive heat therapy to optimise cardiorespiratory fitness prior to total hip or knee arthroplasty: A randomised controlled trial. Arthritis Care & Research, 25238. Advance online publication. doi: 10.1002/acr.25238 Journal - Research Article

Bellae Papannarao, J., Coffey, S., Williams, M., McLelland, M., & Katare, R. (2023, August). Circulating microRNAs as prognostic biomarkers for ischemic heart disease. Poster session presented at the 17th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)

Tonkin, D., Williams, M., Schwenke, D., & Katare, R. (2023, August). Effects of synthetic miRNA cocktail for activation of endogenous progenitor cells in the diabetic heart. Verbal presentation at the 17th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs

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