Contact Details
- Phone
- +64 3 470 9543
- greg.jones@otago.ac.nz
University Links
- Position
- Research Professor
- Department
- Department of Surgical Sciences (Dunedin)
- Qualifications
- BSc PhD(Otago)
- Research summary
- Vascular disease genetics, biomarker discovery, and histopathology
Research
Professor Jones' research group has a broad range of interests in the field of vascular biology, including population genetics, cardiovascular disease biomarkers, and vascular connective tissue biology. The group's research has a strong clinical emphasis, particularly in the areas of aortic aneurysm, coronary and peripheral arterial disease and varicose veins.
The Vascular Research Group has four main areas of research focus:
- Genes associated with the initiation and progression of vascular diseases
- Identifying circulating biomarkers to assess vascular disease risk
- The early structural and molecular features of human arterial disease
- The pathobiology of lower limb venous disease, including varicose veins, venous ulcers and post-operative recurrence
- The techniques used in the Vascular Research Group include whole genome scanning, microRNA and mRNA microarray, proteomics, immunohistochemistry, cell culture, and functional assays.
The group is currently funded by the Health Research Council of New Zealand.
Publications
Fitzgerald, S., Bhat, B., Print, C., & Jones, G. T. (2024). A validated restriction enzyme ddPCR cg05575921 (AHRR) assay to accurately assess smoking exposure [Brief Report]. Clinical Epigenetics, 16, 45. doi: 10.1186/s13148-024-01659-1 Journal - Research Other
Cameron, V. A., Jones, G. T., Horwood, L. J., Pilbrow, A. P., Martin, J., Frampton, C., Ip, W. T., Troughton, R. W., Greer, C., Yang, J., Epton, M. J., Harris, S. L., & Darlow, B. A. (2023). DNA methylation patterns at birth predict health outcomes in young adults born very low birthweight. Clinical Epigenetics, 15, 47. doi: 10.1186/s13148-023-01463-3 Journal - Research Article
Roychowdhury, T., Klarin, D., Levin, M. G., Spin, J. M., Rhee, Y. H., Deng, A., … Jones, G. T., … Damrauer, S. M. (2023). Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target. Nature Genetics. Advance online publication. doi: 10.1038/s41588-023-01510-y Journal - Research Article
Hall, N., Krysa, J., Lesche, S., Hill, B. G., Letts, J. A., McNaughton, A., Clifford, K., & Jones, G. T. (2022). Near infrared fluorescence imaging to demonstrate reflux in the superficial microvenous network of the leg. European Journal of Vascular & Endovascular Surgery, 64, 377-386. doi: 10.1016/j.ejvs.2022.05.036 Journal - Research Article
Bhat, B., & Jones, G. T. (2023). Gaps in current methods to detect polymorphic CpGs from Illumina Infinium human methylation microarrays and exploring their potential impact in multi-EWAS analyses [Brief report]. Epigenetics, 18(1), 2281153. doi: 10.1080/15592294.2023.2281153 Journal - Research Other
Pinard, A., Jones, G. T., & Milewicz, D. M. (2019). Genetics of thoracic and abdominal aortic diseases: Aneurysms, dissections, and ruptures. Circulation Research, 124(4), 588-606. doi: 10.1161/circresaha.118.312436 Journal - Research Article
Jones, G. T., Tromp, G., Kuivaniemi, H., Gretarsdottir, S., Baas, A. F., Giusti, B., … Phillips, L. V., Williams, M. J. A., Wei, W., … Thomson, I. A., Krysa, J., Hill, G. B., Roake, J., Merriman, T. R., … van Rij, A., … Bown, M. J. (2017). Meta-analysis of genome-wide association studies for abdominal aortic aneurysm identifies four new disease-specific risk loci. Circulation Research, 120, 341-353. doi: 10.1161/circresaha.116.308765 Journal - Research Article
Moore, M. K., Jones, G. T., McCormick, S., Williams, M. J. A., & Coffey, S. (2024). Association between lipoprotein(a), LPA genetic risk score, aortic valve disease, and subsequent major adverse cardiovascular events. European Journal of Preventive Cardiology. Advance online publication. doi: 10.1093/eurjpc/zwae100 Journal - Research Article
Powell, R. M., Moravec, J. C., Jones, G. T., Bhat, B., Lin, S. M., Planer, J. D., … Pattison, S., Morison, I. M., … Eccles, M. R., & Macaulay, E. C. (2024). DNA methylation profiling of heterogeneous sporadic LAM and matched lung tissue. American Journal of Respiratory Cell & Molecular Biology, 70(1), 81-84. doi: 10.1165/rcmb.2023-0300LE Journal - Research Other
Moore, M. K., Whalley, G., Jones, G. T., & Coffey, S. (2024). Use of an ultrasound picture archiving and communication system to answer research questions: Description of data cleaning methods. Australasian Journal of Ultrasound in Medicine. Advance online publication. doi: 10.1002/ajum.12374 Journal - Research Article
Bakker, M. K., Kanning, J. P., Abraham, G., Martinsen, A. E., Winsvold, B. S., Zwart, J.-A., … Jones, G., … Ruigrok, Y. M. (2023). Genetic risk score for intracranial aneurysms: Prediction of subarachnoid hemorrhage and role in clinical heterogeneity. Stroke, 54(3), 810-818. doi: 10.1161/strokeaha.122.040715 Journal - Research Article
Moore, M. K., Jones, G. T., Whalley, G., Prendergast, B., Williams, M. J. A., & Coffey, S. (2023). Outcomes of patients with early calcific aortic valve disease detected by clinically indicated echocardiography. European Heart Journal: Cardiovascular Imaging. Advance online publication. doi: 10.1093/ehjci/jead259 Journal - Research Article
Bhat, B., & Jones, G. T. (2022). Data analysis of DNA methylation Epigenome-Wide Association Studies (EWAS): A guide to the principles of best practice. In J. Horsfield & J. Marsman (Eds.), Chromatin: Methods and protocols: Methods in molecular biology (Vol. 2458). (pp. 23-45). New York, NY: Springer. doi: 10.1007/978-1-0716-2140-0_2 Chapter in Book - Research
Klarin, D., Verma, S. S., Judy, R., Dikilitas, O., Wolford, B. N., Paranjpe, I., … Jones, G. T., … Tsao, P. S. (2020). Genetic architecture of abdominal aortic aneurysm in the Million Veteran Program. Circulation, 142(17), 1633-1646. doi: 10.1161/circulationaha.120.047544 Journal - Research Article
Jones, G. T., Marsman, J., Bhat, B., Phillips, V. L., Chatterjee, A., Rodger, E. J., Williams, M. J. A., van Rij, A. M., & McCormick, S. P. A. (2020). DNA methylation profiling identifies a high effect genetic variant for lipoprotein(a) levels. Epigenetics, 15(9), 949-958. doi: 10.1080/15592294.2020.1739797 Journal - Research Article
Clifford, K., Majumder, A., Hill, B., Young-Gough, A., Jones, G. T., & Krysa, J. (2022). The impact of suprarenal diameter on outcomes following endovascular aneurysm repair: A retrospective cohort study. Vascular & Endovascular Surgery, 56(7), 682-688. doi: 10.1177/15385744221108052 Journal - Research Article
Ghosh, N., Fenton, S., van Hout, I., Jones, G. T., Coffey, S., Williams, M. J. A., Sugunesegran, R., Parry, D., … Schwenke, D. O., Chatterjee, A., & Katare, R. (2022). Therapeutic knockdown of miR-320 improves deteriorated cardiac function in a pre-clinical model of non-ischemic diabetic heart disease. Molecular Therapy: Nucleic Acids, 29, 330-342. doi: 10.1016/j.omtn.2022.07.007 Journal - Research Article
Morris, D. R., Jones, G. T., Holmes, M. V., Bown, M. J., Bulbulia, R., Singh, T. P., & Golledge, J. (2022). Genetic predisposition to diabetes and abdominal aortic aneurysm: A two stage Mendelian randomisation study. European Journal of Vascular & Endovascular Surgery, 63, 512-519. doi: 10.1016/j.ejvs.2021.10.038 Journal - Research Article
Powell, R. M., Pattison, S., Moravec, J. C., Bhat, B., Guirguis, N., Markie, D., Jones, G. T., … Print, C. G., Morison, I. M., Gavryushkin, A., … Eccles, M. R., & Macaulay, E. C. (2022). Tuberous sclerosis complex: A complex case. Molecular Case Studies, 8, a006182. doi: 10.1101/mcs.a006182 Journal - Research Article
Golledge, J., Arnott, C., Moxon, J., Monaghan, H., Norman, R., Morris, D., … Jones, G., Roake, J., … Neal, B. (2021). Protocol for the Metformin Aneurysm Trial (MAT): A placebo-controlled randomised trial testing whether metformin reduces the risk of serious complications of abdominal aortic aneurysm. Trials, 22(1), 962. doi: 10.1186/s13063-021-05915-0 Journal - Research Other
Steffensen, L. B., Stubbe, J., Lindholt, J. S., Beck, H. C., Overgaard, M. T., Bloksgaard, M., … Jones, G. T., … Rasmussen, L. M. (2021). Basement membrane collagen IV deficiency promotes abdominal aortic aneurysm formation. Scientific Reports, 11(1), 12903. doi: 10.1038/s41598-021-92303-y Journal - Research Article
Singh, T. P., Field, M. A., Bown, M. J., Jones, G. T., & Golledge, J. (2021). Systematic review of genome-wide association studies of abdominal aortic aneurysm. Atherosclerosis, 327, 39-48. doi: 10.1016/j.atherosclerosis.2021.05.001 Journal - Research Article
Bruijn, L. E., van Stroe Gómez, C. G., Curci, J. A., Golledge, J., Hamming, J. F., Jones, G. T., … Lindemann, J. H. (2021). A histopathological classification scheme for abdominal aortic aneurysm disease. JVS Vascular Science, 2(C), 260-273. doi: 10.1016/j.jvssci.2021.09.001 Journal - Research Article
Marsman, J., Gimenez, G., Day, R. C., Horsfield, J. A., & Jones, G. T. (2020). A non-coding genetic variant associated with abdominal aortic aneurysm alters ERG gene regulation. Human Molecular Genetics, 29(4), 554-565. doi: 10.1093/hmg/ddz256 Journal - Research Article
Bakker, M. K., van der Spek, R. A. A., van Rheenen, W., Morel, S., Bourcier, R., Hostettler, I. C., … Jones, G. T., … Ruigrok, Y. M. (2020). Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors. Nature Genetics, 52, 1303-1313. doi: 10.1038/s41588-020-00725-7 Journal - Research Article
Jones, G. T., Drinkwater, B., Blake-Barlow, A., Hill, G. B., Williams, M. J. A., Krysa, J., van Rij, A. M., & Coffey, S. (2020). Both small and large infrarenal aortic size is associated with an increased prevalence of ischaemic heart disease. European Journal of Vascular & Endovascular Surgery, 60, 594-601. doi: 10.1016/j.ejvs.2020.06.025 Journal - Research Article
Kader, T., Porteous, C. M., Jones, G. T., Dickerhof, N., Narayana, V. K., Tull, D., Taraknath, S., & McCormick, S. P. A. (2020). Ribose-cysteine protects against the development of atherosclerosis in apoE-deficient mice. PLoS ONE, 15(2), e0228415. doi: 10.1371/journal.pone.0228415 Journal - Research Article
Neale, J. P. H., Pearson, J. T., Thomas, K. N., Tsuchimochi, H., Hosoda, H., Kojima, M., … Jones, G. T., Denny, A. P., Daniels, L. J., Chandrasekera, D., Liu, P., van Rij, A. M., Katare, R., & Schwenke, D. O. (2020). Dysregulation of ghrelin in diabetes impairs the vascular reparative response to hindlimb ischemia in a mouse model; Clinical relevance to peripheral artery disease. Scientific Reports, 10, 13651. doi: 10.1038/s41598-020-70391-6 Journal - Research Article
Jones, G. T., Marsman, J., Pardo, L. M., Nijsten, T., De Maeseneer, M., Phillips, V., Lynch-Sutherland, C., Horsfield, J., Krysa, J., & van Rij, A. M. (2019). A variant of the castor zinc finger 1 (CASZ1) gene is differentially associated with the clinical classification of chronic venous disease. Scientific Reports, 9, 14011. doi: 10.1038/s41598-019-50586-2 Journal - Research Article
Chandrasekera, D. N. K., Neale, J. P. H., van Hout, I., Rawal, S., Coffey, S., Jones, G. T., … Manning, P., Williams, M. J. A., & Katare, R. (2020). Upregulation of microRNA-532 enhances cardiomyocyte apoptosis in the diabetic heart. Apoptosis, 25(5-6), 388-399. doi: 10.1007/s10495-020-01609-1 Journal - Research Article
Jones, G. T., Sandiford, P., Hill, G. B., Williams, M. J. A., Khashram, M., Tilyard, M. W., Hammond-Tooke, G. D., Krysa, J., & van Rij, A. M. (2019). Correcting for body surface area identifies the true prevalence of abdominal aortic aneurysm in screened women. European Journal of Vascular & Endovascular Surgery, 57(2), 221-228. doi: 10.1016/j.ejvs.2018.08.048 Journal - Research Article
Jones, G. T., Hill, B. G., Curtis, N., Kabir, T. D., Wong, L. E., Tilyard, M. W., Williams, M. J. A., & van Rij, A. M. (2016). Comparison of three targeted approaches to screening for abdominal aortic aneurysm based on cardiovascular risk. British Journal of Surgery, 103(9), 1139-1146. doi: 10.1002/bjs.10224 Journal - Research Article
Nair, N., Kvizhinadze, G., Jones, G. T., Rush, R., Khashram, M., Roake, J., & Blakely, A. (2019). Health gains, costs and cost-effectiveness of a population-based screening programme for abdominal aortic aneurysms. British Journal of Surgery, 106(8), 1043-1054. doi: 10.1002/bjs.11169 Journal - Research Article
Harrison, S. C., Holmes, M. V., Burgess, S., Asselbergs, F. W., Jones, G. T., Baas, A. F., … van Rij, A. M., … Humphries, S. E. (2018). Genetic association of lipids and lipid drug targets with abdominal aortic aneurysm: A meta-analysis. JAMA Cardiology, 3(1), 26-33. doi: 10.1001/jamacardio.2017.4293 Journal - Research Article
Khashram, M., Kvizhinadze, G., Khashram, Z., Williman, J. A., Jones, G. T., & Roake, J. A. (2018). Development and validation of a predictive model to aid in the management of intact abdominal aortic aneurysms. European Journal of Vascular & Endovascular Surgery, 56(1), 48-56. doi: 10.1016/j.ejvs.2018.03.013 Journal - Research Article
Roberts, R. L., Wallace, M. C., Seinen, M. L., van Bodegraven, A. A., Krishnaprasad, K., Jones, G. T., van Rij, A. M., … Kennedy, M. A., … Gearry, R. B., … Barclay, M. (2018). Nonsynonymous polymorphism in guanine monophosphate synthetase is a risk factor for unfavorable thiopurine metabolite ratios in patients with inflammatory bowel disease. Inflammatory Bowel Diseases, 24(12), 2606-2612. doi: 10.1093/ibd/izy163 Journal - Research Article
Rodger, E. J., Porteous, C. M., Jones, G. T., Legge, M., Kleffmann, T., & McCormick, S. P. A. (2018). Proteomic analysis of liver from lipoprotein(a) transgenic mice shows an oxidative stress and lipid export response. BioMed Research International, 2018, 4963942. doi: 10.1155/2018/4963942 Journal - Research Article
Khashram, M., Pitama, S., Williman, J. A., Jones, G. T., & Roake, J. A. (2017). Survival disparity following abdominal aortic aneurysm repair highlights Inequality in ethnic and socio-economic status. European Journal of Vascular & Endovascular Surgery, 54(6), 689-696. doi: 10.1016/j.ejvs.2017.08.018 Journal - Research Article
Rawal, S., Munasinghe, E. P., Nagesh, P. T., Lew, J. K. S., Jones, G. T., Williams, M. J. A., Davis, P., Bunton, R. W., Galvin, I. F., Manning, P., Lamberts, R. R., & Katare, R. (2017). Downregulation of miR-15a/b accelerates fibrotic remodelling in the Type-2 diabetic human and mouse heart. Clinical Science, 131(9), 847-863. doi: 10.1042/cs20160916 Journal - Research Article
Khashram, M., Williman, J. A., Hider, P. N., Jones, G. T., & Roake, J. A. (2017). Management of modifiable vascular risk factors improves late survival following abdominal aortic aneurysm repair? A systematic review and meta-analysis. Annals of Vascular Surgery, 39, 301-311. doi: 10.1016/j.avsg.2016.07.066 Journal - Research Article
Khashram, M., Tiong, L. C., Jones, G. T., & Roake, J. A. (2017). The impact of CT colonography on abdominal aortic aneurysm referrals in a tertiary hospital. Journal of Medical Imaging & Radiation Oncology, 61(2), 180-184. doi: 10.1111/1754-9485.12535 Journal - Research Article
Rawal, S., Munasinghe, P. E., Shindikar, A., Paulin, J., Cameron, V., Manning, P., Williams, M. J. A., Jones, G. T., Bunton, R., Galvin, I., & Katare, R. (2017). Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy. Cardiovascular Research, 113(1), 90-101. doi: 10.1093/cvr/cvw235 Journal - Research Article
Khashram, M., Thomson, I. A., Jones, G. T., & Roake, J. A. (2017). Abdominal aortic aneurysm repair in New Zealand: A validation of the Australasian Vascular Audit. ANZ Journal of Surgery, 87(5), 394-398. doi: 10.1111/ans.13702 Journal - Research Article
Telomeres Mendalian Randomization Collaboration, including van Rij, A., & Jones, G. T. (2017). Association between telomere length and risk of cancer and non-neoplastic diseases: A Mendelian randomization study. JAMA Oncology, 3(5), 636-651. doi: 10.1001/jamaoncol.2016.5945 Journal - Research Article
Phipps-Green, A. J., Merriman, M. E., Topless, R., Altaf, S., Montgomery, G. W., Franklin, C., Jones, G. T., van Rij, A. M., … Stamp, L. K., … Merriman, T. R. (2016). Twenty-eight loci that influence serum urate levels: Analysis of association with gout. Annals of the Rheumatic Diseases, 75, 124-130. doi: 10.1136/annrheumdis-2014-205877 Journal - Research Article
Jones, G. T., Phillips, V., Williams, M. J. A., van Rij, A. M., & Kabir, T. D. (2016). Two C-C family chemokines, eotaxin and RANTES, are novel independent plasma biomarkers for abdominal aortic aneurysm. Journal of the American Heart Association, 5(5), e002993. doi: 10.1161/jaha.115.002993 Journal - Research Article
van 't Hof, F. N. G., Ruigrok, Y. M., Lee, C. H., Ripke, S., Anderson, G., de Andrade, M., … Jones, G. T., … van Rij, A. M., … Vascular Research Consortium of New Zealand, including Phillips, L. V., Hill, G. B., Williams, M. J. A., Thomson, I. A., Krysa, J., Wilkins, G. T., Merriman, T. R., Lewis, D. R., … de Bakker, P. I. W. (2016). Shared genetic risk factors of intracranial, abdominal, and thoracic aneurysms. Journal of the American Heart Association, 5(7), e002603. doi: 10.1161/jaha.115.002603 Journal - Research Article
Coffey, S., Williams, M. J. A., Phillips, L. V., Galvin, I. F., Bunton, R. W., & Jones, G. T. (2016). Integrated microRNA and messenger RNA analysis in aortic stenosis. Scientific Reports, 6, 36904. doi: 10.1038/srep36904 Journal - Research Article
Rasheed, H., Phipps-Green, A. J., Topless, R., Smith, M. D., Hill, C., Lester, S., … van Rij, A., Jones, G. T., McCormick, S. P., Harrison, A. A., Stamp, L. K., … Merriman, T. R. (2016). Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout. Rheumatology, 55(8), 1421-1430. doi: 10.1093/rheumatology/kew057 Journal - Research Article
Munasinghe, P. E., Riu, F., Dixit, P., Edamatsu, M., Saxena, P., Hamer, N. S. J., Galvin, I. F., Bunton, R. W., Lequeux, S., Jones, G., Lamberts, R. R., … Katare, R. (2016). Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway. International Journal of Cardiology, 202, 13-20. doi: 10.1016/j.ijcard.2015.08.111 Journal - Research Article
Khashram, M., Jones, G. T., & Roake, J. A. (2016). Re: 'Self-referral to the NHS Abdominal Aortic Screening Programme'. European Journal of Vascular & Endovascular Surgery, 52(2), 270-271. doi: 10.1016/j.ejvs.2016.05.023 Journal - Research Other
Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., … Williams, M. J. A., van Rij, A. M., Jones, G. T., … Stefansson, K. (2016). Variant ASGR1 associated with a reduced risk of coronary artery disease. New England Journal of Medicine, 374, 2131-2141. doi: 10.1056/NEJMoa1508419 Journal - Research Article
Khashram, M., Hider, P. N., Williman, J. A., Jones, G. T., & Roake, J. A. (2016). Does the diameter of abdominal aortic aneurysm influence late survival following abdominal aortic aneurysm repair? A systematic review and meta-analysis. Vascular, 24(6), 658-667. doi: 10.1177/1708538116650580 Journal - Research Article
Khashram, M., Williman, J. A., Hider, P. N., Jones, G. T., & Roake, J. A. (2016). Systematic review and meta-analysis of factors influencing survival following abdominal aortic aneurysm repair. European Journal of Vascular & Endovascular Surgery, 51(2), 203-215. doi: 10.1016/j.ejvs.2015.09.007 Journal - Research Article
The Interleukin 1 Genetics Consortium, including Jones, G. T., & van Rij, A. (2015). Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A Mendelian randomisation analysis. Lancet Diabetes & Endocrinology, 3(4), 243-253. doi: 10.1016/S2213-8587(15)00034-0 Journal - Research Article
Coffey, S., Williams, M. J. A., Phillips, L. V., & Jones, G. T. (2015). Circulating microRNA profiling needs further refinement before clinical use in patients with aortic stenosis. Journal of the American Heart Association, 4(8), e002150. doi: 10.1161/jaha.115.002150 Journal - Research Article
Khashram, M., Jones, G. T., & Roake, J. A. (2015). Prevalence of abdominal aortic aneurysm (AAA) in a population undergoing computed tomography colonography in Canterbury, New Zealand. European Journal of Vascular & Endovascular Surgery, 50(2), 199-205. doi: 10.1016/j.ejvs.2015.04.023 Journal - Research Article
Sharma, M., Von Zychlinski-Kleffmann, A., Porteous, C. M., Jones, G. T., Williams, M. J. A., & McCormick, S. P. A. (2015). Lipoprotein (a) upregulates ABCA1 in liver cells via scavenger receptor-B1 through its oxidized phospholipids. Journal of Lipid Research, 56, 1318-1328. doi: 10.1194/jlr.M056150 Journal - Research Article
van Rij, A. M., & Jones, G. T. (2015). Aortic aneurysm screening. British Journal of Surgery, 102(8), 863-865. doi: 10.1002/bjs.9830 Journal - Research Other
Jin, C., Phillips, L. V., Williams, M. J. A., van Rij, A. M., & Jones, G. T. (2014). Plasma heat shock protein 27 is associated with coronary artery disease, abdominal aortic aneurysm and peripheral artery disease. SpringerPlus, 3, 635. doi: 10.1186/2193-1801-3-635 Journal - Research Article
Coffey, S., & Jones, G. T. (2014). MicroRNAs are central to osteogenesis: A review with a focus on cardiovascular calcification. microRNA Diagnostics & Therapeutics, 1, 113-125. doi: 10.2478/micrnat-2014-0005 Journal - Research Article
Jones, G. T. (2014). Matrix metalloproteinases in biologic samples. In G. S. Makowski (Ed.), Advances in clinical chemistry (Vol. 65). (pp. 199-219). Elsevier. doi: 10.1016/B978-0-12-800141-7.00007-3 Chapter in Book - Research
Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2013). Plasma active matrix metalloproteinase 9 and indices of diastolic function in patients with preserved systolic function. International Journal of Cardiology, 167(4), 1242-1246. doi: 10.1016/j.ijcard.2012.03.147 Journal - Research Article
Harrison, S. C., Smith, A. J. P., Jones, G. T., Swerdlow, D. I., Rampuri, R., Brown, M. J., … Humphries, S. E. (2013). Interleukin-6 receptor pathways in abdominal aortic aneurysm. European Heart Journal, 34(48), 3707-3716. doi: 10.1093/eurheartj/ehs354 Journal - Research Article
Dennis, N. A., Jones, G. T., Chong, Y. H., van Rij, A. M., & McLennan, I. S. (2013). Serum anti-Müllerian hormone (AMH) levels correlate with infrarenal aortic diameter in healthy older men: Is AMH a cardiovascular hormone? Journal of Endocrinology, 219, 13-20. doi: 10.1530/joe-13-0125 Journal - Research Article
Tarr, G. P., Williams, M. J. A., Wilkins, G. T., Chen, V. H. T., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2013). Intra-individual changes of active matrix metalloproteinase-9 are associated with clinical in-stent restenosis of bare metal stents. Cardiology, 124(1), 28-35. doi: 10.1159/000345591 Journal - Research Article
Bradley, D. T., Hughes, A. E., Badger, S. A., Jones, G. T., Harrison, S. C., Wright, B. J., … van Rij, A., … Bown, M. J. (2013). A variant in LDLR is associated with abdominal aortic aneurysm. Circulation: Cardiovascular Genetics, 6, 498-504. doi: 10.1161/CIRCGENETICS.113.000165 Journal - Research Article
Jones, G. T., Bown, M. J., Gretarsdottir, S., Romaine, S. P. R., Helgadottir, A., Yu, G., … Jin, C., … Phillips, L. V., Williams, M. J. A., Topless, R., Merriman, T. R., … Lewis, D. R., … van Rij, A. M. (2013). A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm. Human Molecular Genetics, 22(14), 2941-2947. doi: 10.1093/hmg/ddt141 Journal - Research Article
Chong, Y. H., Dennis, N. A., Connolly, M. J., Teh, R., Jones, G. T., van Rij, A. M., … Campbell, A. J., & McLennan, I. S. (2013). Elderly men have low levels of anti-Müllerian hormone and inhibin B, but with high interpersonal variation: A cross-sectional study of the Sertoli cell hormones in 615 community-dwelling men. PLoS ONE, 8(8), e70967. doi: 10.1371/ journal.pone.0070967 Journal - Research Article
Kuivaniemi, H., Sakalihasan, N., Lederle, F. A., Jones, G. T., Defraigne, J.-O., Labropoulos, N., … Elefteriades, J. A. (2013). New insights into aortic disease: A report from the Third International Meeting on Aortic Diseases (IMAD3). Aorta, 1(1), 23-39. doi: 10.12945/j.aorta.2013.13.006 Journal - Research Other
Krysa, J., Jones, G. T., & van Rij, A. M. (2012). Evidence for a genetic role in varicose veins and chronic venous insufficiency. Phlebology, 27(7), 329-335. doi: 10.1258/phleb.2011.011030 Journal - Research Article
Harrison, S. C., Zabaneh, D., Asselbergs, F. W., Drenos, F., Jones, G. T., Shah, S., … van Rij, A. M., … Humphries, S. E. (2013). A gene-centric study of common carotid artery remodeling. Atherosclerosis, 226(2), 440-446. doi: 10.1016/j.atherosclerosis.2012.11.002 Journal - Research Article
Sorrenson, B., Suetani, R. J., Williams, M. J. A., Bickley, V. M., George, P. M., Jones, G. T., & McCormick, S. P. A. (2013). Functional rescue of mutant ABCA1 proteins by sodium 4-phenylbutyrate. Journal of Lipid Research, 54, 55-62. doi: 10.1194/jlr.M027193 Journal - Research Article
Helgadottir, A., Gretarsdottir, S., Thorleifsson, G., Holm, H., Patel, R. S., Gudnason, T., Jones, G. T., van Rij, A. M., … Stefansson, H. (2012). Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. JACC, 60(8), 722-729. doi: 10.1016/j.jacc.2012.01.078 Journal - Research Article
Roberts, R. L., Wallace, M. C., Jones, G. T., van Rij, A. M., Merriman, T. R., Harrison, A., … Stamp, L. K., … Highton, J., & Stebbings, S. M. (2013). Prevalence of HLA-B27 in the New Zealand population: Effect of age and ethnicity. Arthritis Research & Therapy, 15, R158. doi: 10.1186/ar4341 Journal - Research Article
Kardys, I., Oemrawsingh, R. M., Kay, P., Jones, G. T., McCormick, S. P. A., Daemen, J., … Serruys, P. (2012). Lipoprotein(a), interleukin-10, C-reactive protein, and 8-year outcome after percutaneous coronary intervention. Clinical Cardiology, 35(8), 482-489. doi: 10.1002/clc.21988 Journal - Research Article
Rodger, E. J., Suetani, R. J., Jones, G. T., Kleffmann, T., Carne, A., Legge, M., & McCormick, S. P. A. (2012). Proteomic analysis of aortae from human lipoprotein(a) transgenic mice shows an early metabolic response independent of atherosclerosis. PLoS ONE, 7(1), e30383. doi: 10.1371/journal.pone.0030383 Journal - Research Article
Chen-Xu, M., Topless, R., McKinney, C., Merriman, M. E., Phipps-Green, A., Dalbeth, N., … Harrison, A. A., Highton, J., … van Rij, A., Jones, G. T., … Stamp, L. K., … Merriman, T. R. (2012). Replication of association of the interleukin 23 receptor rs1343151 variant with rheumatoid arthritis in Caucasian sample sets. Annals of the Rheumatic Diseases, 71(1), 155-157. doi: 10.1136/annrheumdis-2011-200591 Journal - Research Article
Dennis, N. A., Houghton, L. A., Jones, G. T., van Rij, A. M., Morgan, K., & McLennan, I. S. (2012). The level of serum anti-Müllerian hormone correlates with vitamin D status in men and women but not in boys. Journal of Clinical Endocrinology & Metabolism, 97(7), 2450-2455. doi: 10.1210/jc.2012-1213 Journal - Research Article
Hollis-Moffatt, J. E., Phipps-Green, A. J., Chapman, B., Jones, G. T., van Rij, A., Gow, P. J., Harrison, A. A., Highton, J., … Stamp, L. K., … Merriman, T. R. (2012). The renal urate transporter SLC17A1 locus: Confirmation of association with gout. Arthritis Research & Therapy, 14(2), R92. doi: 10.1186/ar3816 Journal - Research Article
Schunkert, H., König, I. R., Kathiresan, S., Reilly, M. P., Assimes, T. L., Holm, H., … Jones, G. T., … van Rij, A. M., … for the CARDIoGRAM Constortium. (2011). Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nature Genetics, 43(4), 333-340. doi: 10.1038/ng.784 Journal - Research Article
Vincent, J. R., Jones, G. T., Hill, G. B., & van Rij, A. M. (2011). Failure of microvenous valves in small superficial veins is a key to the skin changes of venous insufficiency. Journal of Vascular Surgery, 54(6, Suppl. ), 62S-69S.e3. doi: 10.1016/j.jvs.2011.06.085 Journal - Research Article
Bown, M. J., Jones, G. T., Harrison, S. C., Wright, B. J., Bumpstead, S., Baas, A. F., … CARDIoGRAM Consortium, GLOBAL BPgen Consortium, DIAGRAM Consortium, VRCNZ Consortium, … van Rij, A., … Samani, N. J. (2011). Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1. American Journal of Human Genetics, 89(5), 619-627. doi: 10.1016/j.ajhg.2011.10.002 Journal - Research Article
Tarr, G. P., Williams, M. J. A., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2011). Pro-MMP-9/TIMP-1 ratio correlates poorly with a direct assessment of MMP-9 activity. Clinical Biochemistry, 44(17-18), 1480-1482. doi: 10.1016/j.clinbiochem.2011.09.019 Journal - Research Article
Golledge, J., Biros, E., Warrington, N., Jones, G. T., Cooper, M., van Rij, A. M., … Norman, P. E. (2011). A population-based study of polymorphisms in genes related to sex hormones and abdominal aortic aneurysm. European Journal of Human Genetics, 19(3), 363-366. doi: 10.1038/ejhg.2010.182 Journal - Research Article
Kapustin, A., Davies, J. D., Reynolds, J. L., McNair, R., Jones, G. T., Sidibe, A., … Shanahan, C. M. (2011). Calcium regulates key components of vascular smooth muscle cell-derived matrix vesicles to enhance mineralization. Circulation Research, 109, e1-e12. doi: 10.1161/CIRCRESAHA.110.238808 Journal - Research Article
Roberts, R. L., van Rij, A. M., Phillips, L. V., Young, S., McCormick, S. P. A., Merriman, T. R., & Jones, G. T. (2011). Interaction of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysms. Atherosclerosis, 218(1), 123-126. doi: 10.1016/j.atherosclerosis.2011.04.043 Journal - Research Article
Biros, E., Norman, P. E., Jones, G. T., van Rij, A. M., Yu, G., Moxon, J. V., … Golledge, J. (2011). Meta-analysis of the association between single nucleotide polymorphisms in TGF-β receptor genes and abdominal aortic aneurysm. Atherosclerosis, 219, 218-223. doi: 10.1016/j.atherosclerosis.2011.07.105 Journal - Research Article
Chu, J. W., Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2011). Plasma active matrix metalloproteinase 9 associated to diastolic dysfunction in patients with coronary artery disease [Letter]. International Journal of Cardiology, 147(2), 336-338. doi: 10.1016/j.ijcard.2010.12.093 Journal - Research Other
Gretarsdottir, S., Baas, A. F., Thorleifsson, G., Holm, H., den Heijer, M., de Vries, J.-P. P. M., … van Rij, A. M., Williams, M. J. A., … Jones, G. T., … Stefansson, K. (2010). Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. Nature Genetics, 42(8), 692-697. doi: 10.1038/ng.622 Journal - Research Article
Thompson, A. R., Cooper, J. A., Jones, G. T., Drenos, F., van Bockxmeer, F. M., Biros, E., … van Rij, A. M., … Humphries, S. E. (2010). Assessment of the association between genetic polymorphisms in transforming growth factor beta, and its binding protein (LTBP), and the presence, and expansion, of Abdominal Aortic Aneurysm. Atherosclerosis, 209, 367-373. doi: 10.1016/j.atherosclerosis.2009.09.073 Journal - Research Article
Thorgeirsson, T. E., Gudbjartsson, D. F., Surakka, I., Vink, J. M., Amin, N., Geller, F., … Jones, G. T., van Rij, A. M., … Stefansson, K. (2010). Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nature Genetics, 42(5), 448-453. doi: 10.1038/ng.573 Journal - Research Article
Tarr, G. P., Williams, M. J. A., Phillips, L. V., van Rij, A. M., & Jones, G. T. (2011). Seasonal variation and stability of matrix metalloproteinase-9 activity and tissue inhibitor of matrix metalloproteinase-1 with storage at -80 oC. Clinical Biochemistry, 44(16), 1346-1348. doi: 10.1016/j.clinbiochem.2011.08.1139 Journal - Research Article
Jones, G. T., Grant, M. W., Thomson, I. A., Hill, B. G., & van Rij, A. M. (2009). Characterization of a porcine model of chronic superficial varicose veins. Journal of Vascular Surgery, 49(6), 1554-1561. doi: 10.1016/j.jvs.2009.01.070 Journal - Research Article
Gudbjartsson, D. F., Bjornsdottir, U. S., Halapi, E., Helgadottir, A., Sulem, P., Jonsdottir, G. M., … Williams, M. J. A., van Rij, A. M., Jones, G. T., … Stefansson, K. (2009). Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nature Genetics, 41(3), 342-347. doi: 10.1038/ng.323 Journal - Research Article
Jones, G. T., Deng, M., Hammond-Tooke, G. D., McCormick, S. P. A., & van Rij, A. M. (2009). Increased plasma lipoprotein(a) found in large-artery atherosclerotic, but not small-artery occlusive, stroke [Letter to the editor]. Clinical Chemistry, 55(10), 1888-1890. doi: 10.1373/clinchem.2009.126771 Journal - Research Other
Chan, E. C., Jones, G. T., Dusting, G. J., Datla, S. R., & Jiang, F. (2009). Prevention of aortic elastic lamina defects by losartan in apolipoprotein E-deficient mouse. Clinical & Experimental Pharmacology & Physiology, 36(9), 919-924. doi: 10.1111/j.1440-1681.2009.05169.x Journal - Research Article
Jones, G. T., Tarr, G. P., Phillips, L. V., Wilkins, G. T., van Rij, A. M., & Williams, M. J. A. (2009). Active matrix metalloproteinases 3 and 9 are independently associated with coronary artery in-stent restenosis. Atherosclerosis, 207(2), 603-607. doi: 10.1016/j.atherosclerosis.2009.05.036 Journal - Research Article
Golledge, J., Clancy, P., Jones, G. T., Cooper, M., Palmer, L. J., van Rij, A. M., & Norman, P. E. (2009). Possible association between genetic polymorphisms in transforming growth factor β receptors, serum transforming growth factor β1 concentration and abdominal aortic aneurysm. British Journal of Surgery, 96(6), 628-632. doi: 10.1002/bjs.6633 Journal - Research Article
Helgadottir, A., Thorleifsson, G., Magnusson, K. P., Grétarsdottir, S., Steinthorsdottir, V., Manolescu, A., Jones, G. T., … van Rij, A. M., … Stefansson, K. (2008). The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm [Letter]. Nature Genetics, 40(2), 217-224. doi: 10.1038/ng.72 Journal - Research Article
Thorgeirsson, T. E., Geller, F., Sulem, P., Rafnar, T., Wiste, A., Magnusson, K. P., … Jones, G. T., … van Rij, A. M., … Stefansson, K. (2008). A variant associated with nicotine dependence, lung cancer and peripheral arterial disease [Letter]. Nature, 452, 638-642. doi: 10.1038/nature06846 Journal - Research Article
Jones, G. T. (2008). Animal models in chronic venous disease ″Interview with G. T. Jones, New Zealand″. Medicographia, 30(2), 154-156. Journal - Research Article
Jones, G. T., Thompson, A. R., van Bockxmeer, F. M., Hafez, H., Cooper, J. A., Golledge, J., … van Rij, A. M. (2008). Angiotensin II type 1 receptor 1166C polymorphism is associated with abdominal aortic aneurysm in three independent cohorts. Arteriosclerosis, Thrombosis, & Vascular Biology, 28, 764-770. doi: 10.1161/ATVBAHA.107.155564 Journal - Research Article
Jones, G. T., van Rij, A. M., Hill, G. B., Wilkins, G. T., & Williams, M. J. A. (2008). Common carotid intimal-medial thickness is associated with coronary in-stent restenosis. Journal for Vascular Ultrasound, 32(3), 129-132. Journal - Research Article
Pascoe, K. C., Wlodek, M. E., & Jones, G. T. (2008). Increased elastic tissue defect formation in the growth restricted Brown Norway rat: A potential link between in utero condition and cardiovascular disease. Pediatric Research, 64, 125-130. Journal - Research Article
van Rij, A. M., Jones, G. T., Hill, B. G., Amer, M., Thomson, I. A., Pettigrew, R. A., & Packer, S. G. K. (2008). Mechanical inhibition of angiogenesis at the saphenofemoral junction in the surgical treatment of varicose veins: Early results of a blinded randomized controlled trial. Circulation, 118, 66-74. doi: 10.1161/CIRCULATIONAHA.107.726869 Journal - Research Article
Slatter, T. L., Jones, G. T., Williams, M. J. A., van Rij, A. M., & McCormick, S. P. A. (2008). Novel rare mutations and promoter haplotypes in ABCA1 contribute to low-HDL-C levels. Clinical Genetics, 73, 179-184. doi: 10.1111/j.1399-0004.2007.00940.x Journal - Research Article
Jones, G. T., van Rij, A. M., Cole, J., Williams, M. J. A., Bateman, E. H., Marcovina, S. M., Deng, M., & McCormick, S. P. A. (2007). Plasma lipoprotein(a) indicates risk for 4 distinct forms of vascular disease. Clinical Chemistry, 53(4), 679-685. Journal - Research Article
Jiang, F., Jones, G. T., & Dusting, G. J. (2007). Failure of antioxidants to protect against angiotensin II-induced aortic rupture in aged apolipoprotein(E)-deficient mice. British Journal of Pharmacology, 152, 880-890. Journal - Research Article
Jones, G. T., Kay, I. P., Chu, J. W. S., Wilkins, G. T., Phillips, L. V., McCormick, M., van Rij, A. M., & Williams, M. J. A. (2006). Elevated plasma active matrix metalloproteinase-9 level is associated with coronary artery in-stent restenosis. Arteriosclerosis, Thrombosis, & Vascular Biology, 26, e121-e125. Journal - Research Article
Jones, G. T., Jiang, F., McCormick, S. P. A., & Dusting, G. J. (2005). Elastic lamina defects are an early feature of aortic lesions in the apolipoprotein E knockout mouse. Journal of Vascular Research, 42, 237-246. Journal - Research Article
Jones, G. T., Harris, E. L., Phillips, L. V., & van Rij, A. M. (2005). The methylenetetrahydrofolate reductase C677T polymorphism does not associate with susceptibility to abdominal aortic aneurysm. European Journal of Vascular & Endovascular Surgery, 30(2), 137-142. doi: 10.1016/j.ejvs.2005.02.047 Journal - Research Article
van Rij, A. M., Jones, G. T., Hill, G., & Jiang, P. (2004). Neovascularisation and recurrent varicose veins: More histologic and ultrasound evidence. Journal of Vascular Surgery, 40(2), 296-302. Journal - Research Article
Jiang, F., Jones, G. T., Husband, A. J., & Dusting, G. J. (2003). Cardiovascular protective effects of synthetic isoflavone derivatives in apolipoprotein E-deficient mice. Journal of Vascular Research, 40, 276-284. Journal - Research Article
Jones, G. T., Phillips, L. V., Harris, E. L., Rossaak, J. I., & van Rij, A. M. (2003). Functional matrix metalloproteinase-9 polymorphism (C-1562T) associated with abdominal aortic aneurysm. Journal of Vascular Surgery, 38, 1363-1367. Journal - Research Article
Harris, E. L., Stoll, M., Jones, G. T., Granados, M. A., Porteous, W. K., van Rij, A. M., & Jacob, H. J. (2001). Identification of two susceptibility loci for vascular fragility in the Brown Norway rat. Physiological Genomics, 6(3), 183-189. Journal - Research Article
Jones, G. T., & van Rij, A. M. (2000). In situ von Willebrand factor staining in human arteries and veins. Thrombosis Research, 97(5), 369-374. Journal - Research Article
Jones, G. T., Harris, E. L., Jacob, H. J., & van Rij, A. M. (2000). Spontaneous elastic tissue lesion in the rat abdominal aorta, a genetically determined phenotype. Journal of Vascular Research, 37, 73-81. Journal - Research Article
Jones, G. T., Solomon, C., Moaveni, A. K., van Rij, A. M., & Galvin, I. F. (2000). Venous morphology predicts CVI class. Phlebology Digest, 13(4), 24-26. Journal - Professional & Other Non-Research Articles
Stehbens, W. E., & Jones, G. T. (1999). Arteriovenous malformations and enothelin-1. Journal of Neurosurgery, 90(3), 605-607. Journal - Professional & Other Non-Research Articles
Jones, G. T., Solomon, C., Moaveni, A., van Rij, A. M., Thomson, I. A., & Galvin, I. (1999). Venous morphology predicts class of chronic venous insufficiency. European Journal of Vascular & Endovascular Surgery, 18(4), 349-354. doi: 10.1053/ejvs.1999.0902 Journal - Research Article
Jones, G., van Rij, A. M., & Thomson, I. A. (1998). Endothelial cell ICAM-1 staining in human carotid arteries. Cardiovascular Pathology, 7(5), 245-250. Journal - Research Article
Jones, G. T., van Rij, A. M., Packer, S. G., Walker, R. J., & Stehbens, W. E. (1998). Venous endothelial changes in therapeutic arteriovenous fistulae. Atherosclerosis, 137, 149-156. Journal - Research Article
Jones, G., & Stehbens, W. E. (1995). The ultrastructure of arteries proximal to chronic experimental carotid-jugular arteriovenous fistulae in rabbits. Pathology, 27, 36-42. Journal - Research Article
Jones, G., & Stehbens, W. E. (1995). Ultrastructure of the afferent arteries of experimental femoral arteriovenous fistulae in rabbits. Pathology, 27, 333-338. Journal - Research Article
Jones, G. T., Stehbens, W. E., & Martin, B. J. (1994). Ultrastructural changes in arteries proximal to short-term experimental carotid—jugular arteriovenous fistulae in rabbits. International Journal of Experimental Pathology, 75, 225-232. Journal - Research Article
Jones, G. T., Martin, B. J., & Stehbens, W. E. (1993). Endothelium in the aorta and ilio-femoral arteries proximal to femoral arteriovenous fistulae in rabbits. Pathology, 25, 277-281. Journal - Research Article
Jones, G. T., Martin, B. J., & Stehbens, W. E. (1992). Endothelium and elastic tears in the afferent arteries of experimental arteriovenous fistulae in rabbits. International Journal of Experimental Pathology, 73, 405-416. Journal - Research Article
Hollis-Moffatt, J. E., Chen-Xu, M., Topless, R., Dalbeth, N., Gow, P. J., Harrison, A. A., Highton, J., … van Rij, A., Jones, G. T., Stamp, L. K., & Merriman, T. R. (2010). Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: Confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance. Arthritis Research & Therapy, 12(3), R116. doi: 10.1186/ar3053 Journal - Research Article
The Aneurysm Consortium, including Jones, G. T., & van Rij, A. M. (2008). Genome wide association studies: Identifying the genes that determine the risk of abdominal aortic aneurysm [Editorial]. European Journal of Vascular & Endovascular Surgery, 36, 395-396. doi: 10.1016/j.ejvs.2008.06.003 Journal - Research Other
Rossaak, J. I., Hill, T. M., Jones, G. T., Phillips, L. V., Harris, E. L., & van Rij, A. M. (2001). Familial abdominal aortic aneurysms in the Otago region of New Zealand. Cardiovascular Surgery, 9, 241-248. Journal - Research Article