Red X iconGreen tick iconYellow tick icon

Contact Details

Email
melanie.millier@otago.ac.nz
Position
Research Fellow
Department
Department of Paediatrics and Child Health (Dunedin)
Qualifications
BSc MSc
Research summary
Measles immunity in young adults, clinical trials using new vaccine methods.
Memberships
  • Research Operations Committee
  • Department of Paediatrics and Child Health: Postgraduate representative

Research

Melanie coordinates the MAXXED clinical trial studies, led by Professor Peter McIntyre. These studies aim to assess measles immunity in young adults and measure responses to new methods of vaccine delivery: aerosol (inhaled) and intradermal (micro-needle). Melanie's PhD research project, supervised by Professors James Ussher (Microbiology and Immunology) and Peter McIntyre (Paediatrics and Child Health), has been designed to maximise the immunological data within the MAXXED study by investigating aspects of mucosal and cell-mediated measles immunity. Comparisons of immune responses amongst the participants receiving different vaccination methods will provide novel insight into how measles immunity might be enhanced by using alternative MMR vaccination techniques and technologies and inform future community vaccination strategies.

Additional details

Medical Sciences Council of New Zealand, Medical Laboratory Scientist (provisional). Available for supervision of summer research students.

Publications

Saha, S., Millier, M., Ussher, J., ten Hulscher-van Overbeek, H., van Binnendijk, R., & McIntyre, P. (2025). Accuracy of measles serology and post M measles antibody responses via alternate vaccine delivery routes. Proceedings of the Infectious Diseases & Pandemic Preparedness Summit. (pp. 39). Retrieved from https://www.teniwha.com Conference Contribution - Published proceedings: Abstract

Saha, S., van Binnendijk, R., Ussher, J., ten Hulscher, H., Millier, M., & McIntyre, P. (2025). Limitations of serological screening for measles immunity in young health care workers in New Zealand. Vaccine, 68. doi: 10.1016/j.vaccine.2025.127931 Journal - Research Article

Saha, S., Millier, M., Ussher, J., Overbeek, H., Binnendijk, R., & McIntyre, P. (2025, September). Low accuracy of routine measles serology in New Zealand and Me antibody responses post MMR given intradermally or by aerosol vs intramuscular route. Workshop presentation at the Aotearoa New Zealand Immunisation Conference, Hamilton, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs

Saha, S., Millier, M., Ussher, J., van Binnendijk, R., & McIntyre, P. (2025). Post-MMR3 measles, mumps, and rubella antibody level changes in seronegative young adults. Proceedings of the Communicable Diseases and Immunisation Conference (CDIC). 324. Retrieved from https://www.cdic2025.com/ Conference Contribution - Published proceedings: Abstract

Saha, S., Millier, M., Samaranayaka, A., Edmonds, L., Best, E., Ussher, J., Anglemyer, A., Lee, J., Tatley, M., … McIntyre, P. (2025). Immunogenicity and safety of measles-mumps-rubella vaccine delivered by the aerosol, intradermal and intramuscular routes in previously vaccinated young adults: A randomized controlled trial protocol. PLoS ONE, 20(3), e0318893. doi: 10.1371/journal.pone.0318893 Journal - Research Other

Back to top