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Pharmacy staff profile

Dr Greg Walker

PositionSenior Lecturer
QualificationsMSc PhD(Otago)
Research summaryDrug delivery and formulation

Research

Bio-conjugation chemistry techniques to engineer nano-devices for application in drug delivery and medical devices. We design and build smart macromolecules which change according to the physiological environment.

Dr Walker on PubMed

Publications

Kramer, K., Young, S. L., & Walker, G. F. (2019). Data on the uptake of reducible antigen-adjuvant conjugates by dendritic cells [Data article]. Data in Brief. Advance online publication. doi: 10.1016/j.dib.2019.103759

Donaldson, B., Lateef, Z., Walker, G. F., Young, S. L., & Ward, V. K. (2018). Virus-like particle vaccines: Immunology and formulation for clinical translation. Expert Review of Vaccines, 17(9), 833-849. doi: 10.1080/14760584.2018.1516552

Kramer, K., Shields, N. J., Poppe, V., Young, S. L., & Walker, G. F. (2017). Intracellular cleavable CpG oligodeoxynucleotide-antigen conjugate enhances anti-tumor immunity. Molecular Therapy, 25(1), 62-70. doi: 10.1016/j.ymthe.2016.10.001

Smith, G. P. S., McLaughlin, A., Clarkson, A. N., Gordon, K. C., & Walker, G. F. (2017). Raman microscopic imaging of electrospun fibers made from a polycaprolactone and polyethylene oxide blend. Vibrational Spectroscopy, 92, 27-34. doi: 10.1016/j.vibspec.2017.05.002

Walker, G., Römann, P., Poller, B., Löbmann, K., Grohganz, H., Rooney, J. S., Huff, G. S., Smith, G. P. S., Rades, T., Gordon, K. C., Strachan, C. J., & Fraser-Miller, S. J. (2017). Probing pharmaceutical mixtures during milling: The potency of low frequency Raman spectroscopy in identifying disorder. Molecular Pharmaceutics, 14(12), 4675-4684. doi: 10.1021/acs.molpharmaceut.7b00803

Journal - Research Article

Kramer, K., Shields, N. J., Poppe, V., Young, S. L., & Walker, G. F. (2017). Intracellular cleavable CpG oligodeoxynucleotide-antigen conjugate enhances anti-tumor immunity. Molecular Therapy, 25(1), 62-70. doi: 10.1016/j.ymthe.2016.10.001

Walker, G., Römann, P., Poller, B., Löbmann, K., Grohganz, H., Rooney, J. S., Huff, G. S., Smith, G. P. S., Rades, T., Gordon, K. C., Strachan, C. J., & Fraser-Miller, S. J. (2017). Probing pharmaceutical mixtures during milling: The potency of low frequency Raman spectroscopy in identifying disorder. Molecular Pharmaceutics, 14(12), 4675-4684. doi: 10.1021/acs.molpharmaceut.7b00803

Smith, G. P. S., McLaughlin, A., Clarkson, A. N., Gordon, K. C., & Walker, G. F. (2017). Raman microscopic imaging of electrospun fibers made from a polycaprolactone and polyethylene oxide blend. Vibrational Spectroscopy, 92, 27-34. doi: 10.1016/j.vibspec.2017.05.002

Kramer, K., Young, S. L., & Walker, G. F. (2017). Comparative study of 5′- and 3′-linked CpG–antigen conjugates for the induction of cellular immune responses. ACS Omega, 2(1), 227-235. doi: 10.1021/acsomega.6b00368

Poller, B., Strachan, C., Broadbent, R., & Walker, G. F. (2017). A minitablet formulation made from electrospun nanofibers. European Journal of Pharmaceutics & Biopharmaceutics, 114, 213-220. doi: 10.1016/j.ejpb.2017.01.022

Yarragudi, S. B., Richter, R., Lee, H., Walker, G. F., Clarkson, A. N., Kumar, H., & Rizwan, S. B. (2017). Formulation of olfactory-targeted microparticles with tamarind seed polysaccharide to improve nose-to-brain transport of drugs. Carbohydrate Polymers, 163, 216-226. doi: 10.1016/j.carbpol.2017.01.044

Fella, C., Walker, G. F., Ogris, M., & Wagner, E. (2008). Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding. European Journal of Pharmaceutical Sciences, 34(4-5), 309-320. doi: 10.1016/j.ejps.2008.05.004

DeRouchey, J., Schmidt, C., Walker, G. F., Koch, C., Plank, C., Wagner, E., & Rädler, J. O. (2008). Monomolecular assembly of siRNA and Poly(ethylene glycol)—peptide copolymers. Biomacromolecules, 9(2), 724-732. doi: 10.1021/bm7011482

Knorr, V., Allmendinger, L., Walker, G. F., Paintner, F. F., & Wagner, E. (2007). An acetal-based PEGylation reagent for pH-sensitive shielding of DNA polyplexes. Bioconjugate Chemistry, 18, 1218-1225. doi: 10.1021/bc060327a

Ledger, R., Tucker, I. G., & Walker, G. F. (2002). Quantitative capillary electrophoresis assay for the proteolytic stability of luteinizing hormone-releasing hormones. Journal of Chromatography B, 769, 235-242.

Ledger, R., Tucker, I. G., & Walker, G. F. (2002). The metabolic barrier of the lower intestinal tract of salmon to the oral delivery of protein and peptide drugs. Journal of Controlled Release, 85, 91-103.

Walker, G. F., Ledger, R., & Tucker, I. G. (2001). Activity of pancreatic endopeptidases towards luteinizing hormone-releasing hormones. International Journal of Pharmaceutics, 216, 77-82.

Walker, G., Ledger, R., & Tucker, I. G. (1999). Garbomer inhibits tryptic proteolysis of luteinizing hormone-releasing hormone and N-alpha-benzoyl-L-arginine ethyl ester by binding the enzyme. Pharmaceutical Research, 16(7), 1074-1080.

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Journal - Research Other

Kramer, K., Young, S. L., & Walker, G. F. (2019). Data on the uptake of reducible antigen-adjuvant conjugates by dendritic cells [Data article]. Data in Brief. Advance online publication. doi: 10.1016/j.dib.2019.103759

Donaldson, B., Lateef, Z., Walker, G. F., Young, S. L., & Ward, V. K. (2018). Virus-like particle vaccines: Immunology and formulation for clinical translation. Expert Review of Vaccines, 17(9), 833-849. doi: 10.1080/14760584.2018.1516552

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