Dr Chihiro Hasegawa

2022

Journal - Research Article

Sharif, S., Hasegawa, C., & Duffull, S. B. (2022). Exploring Inductive Linearization for simulation and estimation with an application to the Michaelis-Menten model. Journal of Pharmacokinetics & Pharmacodynamics, 49, 445-453. doi: 10.1007/s10928-022-09813-z

Journal - Research Other

Derbalah, A., Al-Sallami, H., Hasegawa, C., Gulati, A., & Duffull, S. B. (2022). A framework for simplification of quantitative systems pharmacology models in clinical pharmacology. British Journal of Clinical Pharmacology, 88, 1430-1440. doi: 10.1111/bcp.14451

2020

Journal - Research Other

Ooi, Q. X., Hasegawa, C., Duffull, S. B., & Wright, D. F. B. (2020). Kinetic-pharmacodynamic model for drugs with non-linear elimination: Parameterisation matters. British Journal of Clinical Pharmacology, 86(2), 196-198. doi: 10.1111/bcp.14154

2019

Journal - Research Other

Hasegawa, C., & Duffull, S. B. (2019). Reusing smaller versions of large models: A case example of reuse of a simplified bone model. Clinical Pharmacology & Therapeutics, 106(6), 1184-1186. doi: 10.1002/cpt.1582

Conference Contribution - Published proceedings: Abstract

Wright, D. F. B., Ooi, Q. X., Hasegawa, C., & Duffull, S. B. (2019). Kinetic-pharmacodynamic models in the setting of non-linear drug elimination. Proceedings of the Twenty-Eighth Annual Meeting of the Population Approach Group in Europe (PAGE). (pp. 525-526). Retrieved from https://www.page-meeting.org

2018

Journal - Research Article

Hasegawa, C., & Duffull, S. B. (2018). Automated scale reduction of nonlinear QSP models with an illustrative application to a bone biology system. CPT: Pharmacometrics & Systems Pharmacology, 7, 562-572. doi: 10.1002/psp4.12324

Hasegawa, C., & Duffull, S. B. (2018). Selection and qualification of simplified QSP models when using model order reduction techniques. AAPS Journal, 20, 2. doi: 10.1208/s12248-017-0170-9

Conference Contribution - Published proceedings: Abstract

Hasegawa, C., & Duffull, S. B. (2018). Linearisation and automatic scale reduction of bone biology QSP models for data-driven analyses. Proceedings of the 19th Annual Population Approach Group in Australia and New Zealand Meeting (PAGANZ). Retrieved from http://paganz.org

Hasegawa, C., & Duffull, S. B. (2018). Simplification of multi-scale systems models for data-driven analyses: What has progressed in these 5 years? Proceedings of the Twenty-Seventh Annual Meeting of the Population Approach Group in Europe (PAGE). (pp. 79). Retrieved from http://www.page-meeting.org/

2017

Journal - Research Article

Hasegawa, C., & Duffull, S. B. (2017). Exploring inductive linearization for pharmacokinetic-pharmacodynamic systems of nonlinear ordinary differential equations. Journal of Pharmacokinetics & Pharmacodynamics, 45(1), 35-47. doi: 10.1007/s10928-017-9527-z

Conference Contribution - Published proceedings: Abstract

Hasegawa, C., & Duffull, S. B. (2017). Solutions for nonlinear ordinary differential equations in pharmacokinetic-pharmacodynamic systems. Proceedings of the 18th Annual Population Approach Group in Australia and New Zealand Meeting (PAGANZ). Retrieved from http://paganz.org

Conference Contribution - Verbal presentation and other Conference outputs

Hasegawa, C., & Duffull, S. B. (2017, September). Applying systems pharmacology models to clinical practice. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand.

2016

Conference Contribution - Published proceedings: Abstract

Hasegawa, C. (2016). Pharmacokinetics and modelling issues for monoclonal antibodies. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) Annual Scientific Meeting. (pp. 22). Retrieved from http://www.queenstownresearchweek.org/index.php/ascept-nz/