Professor Paul Cooper

2024

Chapter in Book - Research

Lundy, F. T., Friedlander, L. T., & Cooper, P. R. (2024). Biological basis for vital pulp treatment. In H. F. Duncan & I. A. El-Karim (Eds.), Vital pulp treatment. (pp. 20-46). Hoboken, NJ: John Wiley & Sons. doi: 10.1002/9781119930419.ch2

Journal - Research Article

Al-Maswary, A. A., Walmsley, A. D., Cooper, P. R., & Scheven, B. A. (2024). Low-intensity pulsed ultrasound induces proliferation of human neural stem cells. Clinical & Translational Discovery, 4, e259. doi: 10.1002/ctd2.259

Hussein, H. R., Abdulkareem, A. A., Milward, M. R., & Cooper, P. R. (2024). E-cadherin and TAC in GCF accurately discriminate periodontal health and disease. Oral Diseases. Advance online publication. doi: 10.1111/odi.14862

2023

Edited Book - Research

Seymour, G. J., Cullinan, M. P., Heng, N. C. K., & Cooper, P. R. (Eds.). (2023). Oral biology: Molecular techniques and applications: Methods in molecular biology (Vol. 2588) (3rd ed.). New York, NY: Springer, 528p. doi: 10.1007/978-1-0716-2780-8

Chapter in Book - Research

Arora, S., Ramachandra, S. S., Cooper, P. R., & Hussaini, H. M. (2023). Prospects of passive immunotherapy to treat pulpal inflammation. In M. T. Rahman, W. Teughels & R. J. Lamont (Eds.), Immunology for Dentistry. (pp. 202-214). Hoboken, NJ: John Wiley & Sons. doi: 10.1002/9781119893035.ch14

Hirschfeld, J., Chicca, I. J., Moonen, C. G. J., White, P. C., Ling, M. R., Wright, H. J., Cooper, P. R., … Chapple, I. L. C. (2023). Characterization, quantification, and visualization of neutrophil extracellular traps. In G. J. Seymour, M. P. Cullinan, N. C. K. Heng & P. R. Cooper (Eds.), Oral biology: Molecular techniques and applications: Methods in molecular biology (Vol. 2588). (3rd ed.) (pp. 451-472). New York, NY: Springer. doi: 10.1007/978-1-0716-2780-8_27

Journal - Research Article

Hussein, H. R., Abdulkareem, A. A., Milward, M. R., & Cooper, P. R. (2023). Ability of gingival crevicular fluid volume, E-cadherin, and total antioxidant capacity levels for predicting outcomes of nonsurgical periodontal therapy for periodontitis patients. Journal of Periodontal Research. Advance online publication. doi: 10.1111/jre.13213

Friedlander, L. T., Wallace, W. D. A., Broadbent, J. M., Hanlin, S. M., Lyons, K. M., Cannon, R. D., & Cooper, P. R. (2023). Preparedness and competency of New Zealand graduates for general dental practice: Perceptions from the workforce. Australian Dental Journal. Advance online publication. doi: 10.1111/adj.12981

Alsamahi, S., Milne, T. J., Hussaini, H. M., Rich, A. M., Cooper, P. R., & Friedlander, L. T. (2023). Effects of glycation end-products on the dental pulp in patients with type 2 diabetes. International Endodontic Journal, 56, 1373-1384. doi: 10.1111/iej.13966

Khurshid, Z., Alfarhan, M. F. A., Bayan, Y., Mazher, J., Adanir, N., Dias, G. J., Cooper, P. R., & Ratnayake, J. (2023). Development, physicochemical characterization and in-vitro biocompatibility study of dromedary camel dentine derived hydroxyapatite for bone repair. PeerJ. Advance online publication. doi: 10.7717/peerj.15711

Virdee, S. S., Bashir, N. Z., Krstic, M., Camilleri, J., Grant, M. M., Cooper, P. R., & Tomson, P. L. (2023). Periradicular tissue fluid-derived biomarkers for apical periodontitis: An in vitro methodological & in vivo cross-sectional study. International Endodontic Journal, 56, 1222-1240. doi: 10.1111/iej.13956

Kearney, M., Cooper, P. R., Smith, A. J., & Duncan, H. F. (2023). Characterisation of miRNA expression in dental pulp cells during epigenetically-driven reparative processes. International Journal of Molecular Sciences, 24, 8631. doi: 10.3390/ijms24108631

Wongviriya, A., Shelton, R. M., Cooper, P. R., Milward, M. R., & Landini, G. (2023). The relationship between sphingosine-1-phosphate receptor 2 and epidermal growth factor in migration and invasion of oral squamous cell carcinoma. Cancer Cell International, 23, 65. doi: 10.1186/s12935-023-02906-w

Saliem, S. S., Bede, S. Y., Abdulkareem, A. A., Abdullah, B. H., Milward, M. R., & Cooper, P. R. (2023). Gingival tissue samples from periodontitis patients demonstrate epithelial–mesenchymal transition phenotype. Journal of Periodontal Research, 58, 247-255. doi: 10.1111/jre.13086

Zhao, R., Wang, T., Yang, R., Adam, L. A., Zaharic, T., Loch, C., Tompkins, G. R., & Cooper, P. R. (2023). Enhancing the student learning experience: Co-teaching biochemistry and clinical sciences within the dental curriculum. Biochemistry & Molecular Biology Education, 51, 146-154. doi: 10.1002/bmb.21701

Journal - Research Other

Khurshid, Z., Adanir, N., Ratnayake, J., Dias, G., & Cooper, P. R. (2023). Demineralized dentin matrix for bone regeneration in dentistry: A critical update. Saudi Dental Journal. Advance online publication. doi: 10.1016/j.sdentj.2023.11.028

Dohan, Z., Friedlander, L. T., Cooper, P. R., Li, K.-C., Ratnayake, J. T., & Mei, M. L. (2023). In vitro models used in the formation of root caries lesions: A review of the literature. Dentistry Journal, 11, 269. doi: 10.3390/dj11120269

Murad, M., & Cooper, P. R. (2023). Regenerative endodontic procedures: Are they more successful in mature permanent teeth with necrotic pulp than in immature teeth? Evidence-Based Dentistry, 24, 125-126. doi: 10.1038/s41432-023-00916-1

Majeed, R., Elnawawy, H. M., Kutty, M. G., Yahya, N. A., Azami, N. H., Kasim, N. H. A., … Cooper, P. R., … Ahmed, H. M. A. (2023). Physicochemical, mechanical and biological properties of nano-calcium silicate-based cements: A systematic review. Odontology, 111, 759-776. doi: 10.1007/s10266-023-00786-0

Imran, E., Cooper, P. R., Ratnayake, J., Ekambaram, M., & Mei, M. L. (2023). Potential beneficial effects of hydroxyapatite nanoparticles on caries lesions in vitro: A review of the literature. Dentistry Journal, 11, 40. doi: 10.3390/dj11020040

Conference Contribution - Verbal presentation and other Conference outputs

Patel, S., Milne, T. J., Hussaini, H. M., Cooper, P. R., & Friedlander, L. T. (2023, July). Hyperglycaemia and the dental pulp: So what about angiogenesis? Verbal presentation at the Faculty of Dentistry Clinical and Research Excellence Symposium, Dunedin, New Zealand.

Chao, H. C., Milne, T. J., Cathro, P., Cooper, P. R., & Friedlander, L. T. (2023, July). Hyperglycaemia promotes mineralisation of human dental pulp cells: An exploratory in vitro study. Verbal presentation at the Faculty of Dentistry Clinical and Research Excellence Symposium, Dunedin, New Zealand.

2022

Chapter in Book - Research

Duncan, H. F., & Cooper, P. R. (2022). The bioactive properties of dentine and molecular advances in pulp regeneration. In H. M. A. Ahmed & P. M. H. Dummer (Eds.), Endodontic advances and evidence-based clinical guidelines. (pp. 51-73). Hoboken, NJ: Wiley Blackwell. doi: 10.1002/9781119553939.ch2

Journal - Research Article

Khurshid, Z., Alfarhan, M. F., Mazher, J., Bayan, Y., Cooper, P. R., Dias, G. J., … Ratnayake, J. (2022). Extraction of hydroxyapatite from camel bone for bone tissue engineering application. Molecules, 27(22), 7946. doi: 10.3390/molecules27227946

Al-Maswary, A. A., O'Reilly, M., Holmes, A. P., Walmsley, A. D., Cooper, P. R., & Scheven, B. A. (2022). Exploring the neurogenic differentiation of human dental pulp stem cells. PLoS ONE, 17(11), e0277134. doi: 10.1371/journal.pone.0277134

Bai, Y., Liu, X., Li, J., Wang, Z., Guo, Q., Xiao, M., Cooper, P. R., … He, W. (2022). Stage-dependent regulation of dental pulp stem cell odontogenic differentiation by transforming growth factor-β1. Stem Cells International, 2022, 2361376. doi: 10.1155/2022/2361376

Saliem, S. S., Bede, S. Y., Cooper, P. R., Abdulkareem, A. A., Milward, M. R., & Abdullah, B. H. (2022). Pathogenesis of periodontitis: A potential role for epithelial-mesenchymal transition. Japanese Dental Science Review, 58, 268-278. doi: 10.1016/j.jdsr.2022.09.001

Hewitt, B., Batt, J., Shelton, R. M., Cooper, P. R., Landini, G., Lucas, R. A., … Milward, M. R. (2022). A 3D printed device for in vitro generation of stratified epithelia at the air-liquid interface. Tissue Engineering Part C: Methods, 28(11), 599-609. doi: 10.1089/ten.TEC.2022.0130

Arora, S., Cooper, P. R., Friedlander, L. T., Seo, B., Rizwan, S. B., Rich, A. M., & Hussaini, H. M. (2022). Potentiality and inflammatory marker expression are maintained in dental pulp cell cultures from carious teeth. International Journal of Molecular Sciences, 23(16), 9425. doi: 10.3390/ijms23169425

Wang, C., Lucas, R., Milward, M., & Cooper, P. R. (2022). Impact of particle morphology on abrasion, polishing and stain removal efficacy in a tooth cleaning model system. Biotribology, 32, 100218. doi: 10.1016/j.biotri.2022.100218

Li, J., Wang, Z., Wang, J., Guo, Q., Fu, Y., Dai, Z., … Cooper, P. R., … He, W. (2022). Amphiregulin regulates odontogenic differentiation of dental pulp stem cells by activation of mitogen-activated protein kinase and the phosphatidylinositol 3-kinase signaling pathways. Stem Cell Research & Therapy, 13(1), 304. doi: 10.1186/s13287-022-02971-4

Pelepenko, L. E., Marciano, M. A., Francati, T. M., Bombarda, G., Antunes, T. B. M., Sorrentino, F., … Cooper, P. R., … Camilleri, J. (2022). Can strontium replace calcium in bioactive materials for dental applications? Journal of Biomedical Materials Research Part A, 110, 1892-1911. doi: 10.1002/jbm.a.37421

Mohamad, S. A., Milward, M. R., Hadis, M. A., Kuehne, S. A., & Cooper, P. R. (2022). Blue light photobiomodulation of dental pulp cells. Lasers in Dental Science, 6, 79-87. doi: 10.1007/s41547-022-00152-3

Yong, D., Choi, J. J. E., Cathro, P., Cooper, P. R., Dias, G., Huang, J., & Ratnayake, J. (2022). Development and analysis of a hydroxyapatite supplemented calcium silicate cement for endodontic treatment. Materials, 15(3), 1176. doi: 10.3390/ma15031176

Virdee, S. S., Bashir, N., Cooper, P. R., & Tomson, P. L. (2022). Exploiting dentine matrix proteins in cell-free approaches for periradicular tissue engineering. Tissue Engineering Part B: Reviews, 28(4), 707-732. doi: 10.1089/ten.TEB.2021.0074

Aral, K., Milward, M. R., & Cooper, P. R. (2022). Inflammasome dysregulation in human gingival fibroblasts in response to periodontal pathogens. Oral Diseases, 28, 216-224. doi: 10.1111/odi.13760

Journal - Research Other

Cooper, P. R., Moffat, S. M., & Thomson, W. M. (2022). Te Kaupeka Pūniho: New Zealand's new dental school. British Dental Journal, 233(2), 154-158. doi: 10.1038/s41415-022-4450-0

Arora, S., Cooper, P. R., Ratnayake, J. T., Friedlander, L. T., Rizwan, S. B., Seo, B., & Hussaini, H. M. (2022). A critical review of in vitro research methodologies used to study mineralization in human dental pulp cell cultures. International Endodontic Journal, 55(Suppl. 1), 3-13. doi: 10.1111/iej.13684

Journal - Professional & Other Non-Research Articles

Cooper, P. (2022). A time of change. New Zealand Dental Journal, 118(1), 2. [Editorial].

Conference Contribution - Published proceedings: Abstract

Adam, L., Zhao, R., Wang, T., Yang, R., Zaharic, T., Loch, C., Tompkins, G., & Cooper, P. (2022). Linking theory to practice: Co-teaching biochemistry in dental education. New Zealand Dental Journal, 118(4), (pp. 172). [Abstract]

Arora, S., Cooper, P., Friedlander, L., Rizwan, S., Seo, B., Rich, A., & Hussaini, H. (2022). Evaluation of IL-23 inhibitor as a pulp immunomodulating agent: An in vitro and in vivo study. New Zealand Dental Journal, 118(4), (pp. 167). [Abstract]

2021

Journal - Research Article

Ngah, N. A., Dias, G. J., Tong, D. C., Mohd Noor, S. N. F., Ratnayake, J., Cooper, P. R., & Hussaini, H. M. (2021). Lyophilised platelet-rich fibrin: Physical and biological characterisation. Molecules, 26(23), 7131. doi: 10.3390/molecules26237131

Jayash, S. N., Cooper, P. R., Shelton, R. M., Kuehne, S. A., & Poologasundarampillai, G. (2021). Novel chitosan-silica hybrid hydrogels for cell encapsulation and drug delivery. International Journal of Molecular Sciences, 22, 12267. doi: 10.3390/ijms222212267

Wang, C., Lucas, R., Milward, M., & Cooper, P. R. (2021). Particle size effects on abrasion, surface polishing and stain removal efficacy in a tooth model system. Biotribology, 28, 100196. doi: 10.1016/j.biotri.2021.100196

Paduano, F., Aiello, E., Cooper, P. R., Marrelli, B., Makeeva, I., Islam, M., … Tatullo, M. (2021). A dedifferentiation strategy to enhance the osteogenic potential of dental derived stem cells. Frontiers in Cell & Developmental Biology, 9, 668558. doi: 10.3389/fcell.2021.668558

Aral, K., Milward, M. R., & Cooper, P. R. (2021). Gene expression profiles of mitochondria-endoplasmic reticulum tethering in human gingival fibroblasts in response to periodontal pathogens. Archives of Oral Biology, 128, 105173. doi: 10.1016/j.archoralbio.2021.105173

Serrage, H. J., Cooper, P. R., Palin, W. M., Horstman, P., Hadis, M., & Milward, M. R. (2021). Photobiomodulation of oral fibroblasts stimulated with periodontal pathogens. Lasers in Medical Science, 36, 1957-1969. doi: 10.1007/s10103-021-03331-z

Mohamad, S. A., Milward, M. R., Kuehne, S. A., Hadis, M. A., Palin, W. M., & Cooper, P. R. (2021). Potential for direct application of blue light for photo-disinfection of dentine. Journal of Photochemistry & Photobiology B, 215, 112123. doi: 10.1016/j.jphotobiol.2021.112123

Gleneadie, H. J., Baker, A. H., Batis, N., Bryant, J., Jiang, Y., Clokie, S. J. H., … Cooper, P. R., … Wiench, M. (2021). The anti-tumour activity of DNA methylation inhibitor 5-aza-2'-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress. Cancer Letters, 501, 172-186. doi: 10.1016/j.canlet.2020.12.029

Arruda-Vasconcelos, R., Louzada, L. M., Feres, M., Tomson, P. L., Cooper, P. R., & Gomes, B. P. F. A. (2021). Investigation of microbial profile, levels of endotoxin and lipoteichoic acid in teeth with symptomatic irreversible pulpitis: A clinical study. International Endodontic Journal, 54, 46-60. doi: 10.1111/iej.13402

Journal - Research Other

Zhao, R., Yang, R., Cooper, P. R., Khurshid, Z., Shavandi, A., & Ratnayake, J. (2021). Bone grafts and substitutes in dentistry: A review of current trends and developments. Molecules, 26(10), 3007. doi: 10.3390/molecules26103007

Mohamad, S. A., Milward, M. R., Hadis, M. A., Kuehne, S. A., & Cooper, P. R. (2021). Photobiomodulation of mineralisation in mesenchymal stem cells. Photochemical & Photobiological Sciences, 20, 699-714. doi: 10.1007/s43630-021-00047-5

El Karim, I. A., Cooper, P. R., About, I., Tomson, P. L., Lundy, F. T., & Duncan, H. F. (2021). Deciphering reparative processes in the inflamed dental pulp. Frontiers in Dental Medicine, 2(8), 651219. doi: 10.3389/fdmed.2021.651219

Arora, S., Cooper, P. R., Friedlander, L. T., Rizwan, S., Seo, B., Rich, A. M., & Hussaini, H. M. (2021). Potential application of immunotherapy for modulation of pulp inflammation: Opportunities for vital pulp treatment. International Endodontic Journal, 54, 1263-1274. doi: 10.1111/iej.13524

Ngah, N. A., Ratnayake, J., Cooper, P. R., Dias, G. J., Tong, D. C., Mohd Noor, S. N. F., & Hussaini, H. M. (2021). Potential of lyophilized platelet concentrates for craniofacial tissue regenerative therapies. Molecules, 26, 517. doi: 10.3390/molecules26030517

2020

Journal - Research Article

Heboyan, A., Syed, A. U. Y., Rokaya, D., Cooper, P. R., Manrikyan, M., & Markaryan, M. (2020). Cytomorphometric analysis of inflammation dynamics in the periodontium following the use of fixed dental prostheses. Molecules, 25, 4650. doi: 10.3390/molecules25204650

Virdee, S. S., Ravaghi, V., Camilleri, J., Cooper, P., & Tomson, P. (2020). Current trends in endodontic irrigation amongst general dental practitioners and dental schools within the United Kingdom and Ireland: A cross-sectional survey. British Dental Journal. Advance online publication. doi: 10.1038/s41415-020-1984-x

Aral, K., Milward, M. R., & Cooper, P. R. (2020). Dysregulation of inflammasomes in human dental pulp cells exposed to Porphyromonas gingivalis and Fusobacterium nucleatum. Journal of Endodontics, 46(9), 1265-1272. doi: 10.1016/j.joen.2020.06.008

Aral, K., Milward, M. R., Gupta, D., & Cooper, P. R. (2020). Effects of Porphyromonas gingivalis and Fusobacterium nucleatum on inflammasomes and their regulators in H400 cells. Molecular Oral Microbiology, 35, 158-167. doi: 10.1111/omi.12302

Aral, K., Milward, M. R., Cooper, P. R., & Guler, O. C. (2020). Evaluation of psychological stress and cortisol levels in males with and without gingivitis. Annals of Medical Research, 27(5), 1459-1464. doi: 10.5455/annalsmedres.2019.11.710

Aral, K., Güler, O. C., Cooper, P. R., Shoker, S., Kuehne, S. A., & Milward, M. R. (2020). Antimicrobial effects of boric acid against periodontal pathogens [Borik Asitin Periodontal Patojenler Üzerine Olan Antimikrobiyal Etkileri]. Ege Üniversitesi Diş Hekimliği Fakültesi Dergisi, 41(1), 20-25. doi: 10.5505/eudfd.2020.04935

Virdee, S. S., Farnell, D. J. J., Silva, M. A., Camilleri, J., Cooper, P. R., & Tomson, P. L. (2020). The influence of irrigant activation, concentration and contact time on sodium hypochlorite penetration into root dentine: An ex vivo experiment. International Endodontic Journal, 53, 986-997. doi: 10.1111/iej.13290

Journal - Research Other

Duncan, H. F., & Cooper, P. R. (2020). Pulp innate immune defense: Translational opportunities. Journal of Endodontics, 46(9, Suppl.), S10-S18. doi: 10.1016/j.joen.2020.06.019

Yamauchi, Y., Cooper, P. R., Shimizu, E., Kobayashi, Y., Smith, A. J., & Duncan, H. F. (2020). Histone acetylation as a regenerative target in the dentine-pulp complex. Frontiers in Genetics, 11, 1. doi: 10.3389/fgene.2020.00001

Aral, K., Milward, M. R., Kapila, Y., Berdeli, A., & Cooper, P. R. (2020). Inflammasomes and their regulation in periodontal disease: A review. Journal of Periodontal Research, 55, 473-487. doi: 10.1111/jre.12733

Journal - Professional & Other Non-Research Articles

Duncan, H. F., & Cooper, P. R. (2020). Réparation des tissus dentaires: Futures possibilités avec les agents biologiques. ENDO: Revue Francophone D'Endodontie, 4(3), 189-200. [Review].

2019

Journal - Research Article

Koutroulis, A., Kuehne, S. A., Cooper, P. R., & Camilleri, J. (2019). The role of calcium ion release on biocompatibility and antimicrobial properties of hydraulic cements. Scientific Reports, 9, 19019. doi: 10.1038/s41598-019-55288-3

Koutroulis, A., Batchelor, H., Kuehne, S. A., Cooper, P. R., & Camilleri, J. (2019). Investigation of the effect of the water to powder ratio on hydraulic cement properties. Dental Materials, 35(8), 1146-1154. doi: 10.1016/j.dental.2019.05.011

Holder, M. J., Wright, H. J., Couve, E., Milward, M. R., & Cooper, P. R. (2019). Neutrophil extracellular traps exert potential cytotoxic and proinflammatory effects in the dental pulp. Journal of Endodontics, 45(5), 513-520.e3. doi: 10.1016/j.joen.2019.02.014

Serrage, H. J., Joanisse, S., Cooper, P. R., Palin, W., Hadis, M., Darch, O., … Milward, M. R. (2019). Differential responses of myoblasts and myotubes to photobiomodulation are associated with mitochondrial number. Journal of Biophotonics, 12(6), e201800411. doi: 10.1002/jbio.201800411

Journal - Research Other

Duncan, H. F., & Cooper, P. R. (2019). Réparation des tissus dentaires: Futures possibilités avec les agents biologiques. ENDO, 13(4), 295-306. [Review].

Cushley, S., Duncan, H. F., Lappin, M. J., Tomson, P. L., Lundy, F. T., Cooper, P., … El Karim, I. A. (2019). Pulpotomy for mature carious teeth with symptoms of irreversible pulpitis: A systematic review. Journal of Dentistry, 88, 103158. doi: 10.1016/j.jdent.2019.06.005

Duncan, H. F., Bjørndal, L., van der Sluis, L., Rechenberg, D. K., Simon, S., Cooper, P. R., … Galler, K. (2019). Third European Society of Endodontology (ESE) research meeting: ACTA, Amsterdam, The Netherlands, 26th October 2018: Deep caries and the exposed pulp: current and emerging therapeutic perspectives. International Endodontic Journal, 52(2), 135-138. doi: 10.1111/iej.13059

Duncan, H. F., Cooper, P. R., & Smith, A. J. (2019). Dissecting dentine–pulp injury and wound healing responses: Consequences for regenerative endodontics. International Endodontic Journal, 52(3), 261-266. doi: 10.1111/iej.13064

Virdee, S. S., Butt, K., Grant, M., Camilleri, J., Cooper, P. R., & Tomson, P. L. (2019). A systematic review of methods used to sample and analyse periradicular tissue fluid during root canal treatment. International Endodontic Journal, 52(8), 1108-1127. doi: 10.1111/iej.13104

2018

Journal - Research Article

Okamoto, M., Takahashi, Y., Komichi, S., Cooper, P. R., & Hayashi, M. (2018). Dentinogenic effects of extracted dentin matrix components digested with matrix metalloproteinases. Scientific Reports, 8, 10690. doi: 10.1038/s41598-018-29112-3

Abdulkareem, A., Shelton, R. M., Landini, G., Cooper, P. R., & Milward, M. R. (2018). Periodontal pathogens promote epithelial-mesenchymal transition in oral squamous carcinoma cells in vitro. Cell Adhesion & Migration, 12(2), 127-137. doi: 10.1080/19336918.2017.1322253

Luo, Z., Wang, Z., He, X., Liu, N., Liu, B., Sun, L., … Cooper, P. (2018). Effects of histone deacetylase inhibitors on regenerative cell responses in human dental pulp cells. International Endodontic Journal, 51(7), 767-778. doi: 10.1111/iej.12779

Robinson, J. P., Macedo, R. G., Verhaagen, B., Versluis, M., Cooper, P. R., van der Sluis, L. W. M., & Walmsley, A. D. (2018). Cleaning lateral morphological features of the root canal: The role of streaming and cavitation. International Endodontic Journal, 51(Suppl. 1), e55-e64. doi: 10.1111/iej.12804

Flight, R., Landini, G., Styles, I. B., Shelton, R. M., Milward, M. R., & Cooper, P. R. (2018). Automated noninvasive epithelial cell counting in phase contrast microscopy images with automated parameter selection. Journal of Microscopy, 271(3), 345-354. doi: 10.1111/jmi.12726

White, P. C., Hirschfeld, J., Milward, M. R., Cooper, P. R., Wright, H. J., Matthews, J. B., & Chapple, I. L. C. (2018). Cigarette smoke modifies neutrophil chemotaxis, neutrophil extracellular trap formation and inflammatory response-related gene expression. Journal of Periodontal Research, 53(4), 525-535. doi: 10.1111/jre.12542

Chicca, I. J., Milward, M. R., Chapple, I. L. C., Griffiths, G., Benson, R., Dietrich, T., & Cooper, P. R. (2018). Development and application of high-content biological screening for modulators of NET production. Frontiers in Immunology, 9, 337. doi: 10.3389/fimmu.2018.00337

Journal - Research Other

Kearney, M., Cooper, P. R., Smith, A. J., & Duncan, H. F. (2018). Epigenetic approaches to the treatment of dental pulp inflammation and repair: Opportunities and obstacles. Frontiers in Genetics, 9, 311. doi: 10.3389/fgene.2018.00311

Marrelli, M., Codispoti, B., Shelton, R. M., Scheven, B. A., Cooper, P. R., Tatullo, M., & Paduano, F. (2018). Dental pulp stem cell mechanoresponsiveness: Effects of mechanical stimuli on dental pulp stem cell behavior. Frontiers in Physiology, 9, 1685. doi: 10.3389/fphys.2018.01685

2017

Journal - Research Article

Castro, S. A., Collighan, R., Lambert, P. A., Dias, I. H. K., Chauhan, P., Bland, C. E., … Cooper, P. R., & Devitt, A. (2017). Porphyromonas gingivalis gingipains cause defective macrophage migration towards apoptotic cells and inhibit phagocytosis of primary apoptotic neutrophils. Cell Death & Disease, 8, e2644. doi: 10.1038/cddis.2016.481

He, X., Jiang, W., Luo, Z., Qu, T., Wang, Z., Liu, N., … Cooper, P. R., & He, W. (2017). IFN-γ 3 regulates human dental pulp stem cells behavior via NF-κB and MAPK signaling. Scientific Reports, 7, 40681. doi: 10.1038/srep40681

Andreev, P. S., Coates, M. I., Karatajūtė-Talimaa, V., Shelton, R. M., Cooper, P. R., & Sansom, I. J. (2017). Elegestolepis and its kin, the earliest monodontode chondrichthyans. Journal of Vertebrate Paleontology, 37(1), e1245664. doi: 10.1080/02724634.2017.1245664

Gao, Q., Cooper, P. R., Walmsley, A. D., & Scheven, B. A. (2017). Role of Piezo channels in ultrasound-stimulated dental stem cells. Journal of Endodontics, 43(7), 1130-1136. doi: 10.1016/j.joen.2017.02.022

Duncan, H. F., Smith, A. J., Fleming, G. J. P., Reid, C., Smith, G., & Cooper, P. R. (2017). Release of bio-active dentine extracellular matrix components by histone deacetylase inhibitors (HDACi). International Endodontic Journal, 50(1), 24-38. doi: 10.1111/iej.12588

Tomson, P. L., Lumley, P. J., Smith, A. J., & Cooper, P. R. (2017). Growth factor release from dentine matrix by pulp-capping agents promotes pulp tissue repair-associated events. International Endodontic Journal, 50(3), 281-292. doi: 10.1111/iej.12624

Wang, C., Lucas, R., Smith, A. J., & Cooper, P. R. (2017). An in vitro screening assay for dental stain cleaning. BMC Oral Health, 17, 37. doi: 10.1186/s12903-016-0328-3

Hadis, M. A., Cooper, P. R., Milward, M. R., Gorecki, P. C., Tarte, E., Churm, J., & Palin, W. M. (2017). Development and application of LED arrays for use in phototherapy research. Journal of Biophotonics, 10(11), 1514-1525. doi: 10.1002/jbio.201600273

Conference Contribution - Published proceedings: Full paper

Smith, A. J., & Cooper, P. R. (2017). Regenerative endodontics: Burning questions. Journal of Endodontics, 43(9, Suppl.), (pp. S1-S6). doi: 10.1016/j.joen.2017.06.002

Cooper, P. R., Chicca, I. J., Holder, M. J., & Milward, M. R. (2017). Inflammation and regeneration in the dentin-pulp complex: Net gain or net loss? Journal of Endodontics, 43(9, Suppl.), (pp. S87-S94). doi: 10.1016/j.joen.2017.06.011

2016

Journal - Research Article

Salehi, S., Cooper, P., Smith, A., & Ferracane, J. (2016). Dentin matrix components extracted with phosphoric acid enhance cell proliferation and mineralization. Dental Materials, 32(3), 334-342. doi: 10.1016/j.dental.2015.11.004

Gao, Q., Walmsley, A. D., Cooper, P. R., & Scheven, B. A. (2016). Ultrasound stimulation of different dental stem cell populations: Role of mitogen-activated protein kinase signaling. Journal of Endodontics, 42(3), 425-431. doi: 10.1016/j.joen.2015.12.019

White, P., Sakellari, D., Roberts, H., Risafi, I., Ling, M., Cooper, P., … Chapple, I. (2016). Peripheral blood neutrophil extracellular trap production and degradation in chronic periodontitis. Journal of Clinical Periodontology, 43(12), 1041-1049. doi: 10.1111/jcpe.12628

Andreev, P., Coates, M. I., Karatajūtė-Talimaa, V., Shelton, R. M., Cooper, P. R., Wang, N.-Z., & Sansom, I. J. (2016). The systematics of the Mongolepidida (Chondrichthyes) and the Ordovician origins of the clade. PeerJ, 4, e1850. doi: 10.7717/peerj.1850

Duncan, H. F., Smith, A. J., Fleming, G. J. P., Partridge, N. C., Shimizu, E., Moran, G. P., & Cooper, P. R. (2016). The histone-deacetylase-inhibitor suberoylanilide hydroxamic acid promotes dental pulp repair mechanisms through modulation of matrix metalloproteinase-13 activity. Journal of Cellular Physiology, 231(4), 798-816. doi: 10.1002/jcp.25128

Journal - Research Other

Smith, A. J., Duncan, H. F., Diogenes, A., Simon, S., & Cooper, P. R. (2016). Exploiting the bioactive properties of the dentin-pulp complex in regenerative endodontics. Journal of Endodontics, 42(1), 47-56. doi: 10.1016/j.joen.2015.10.019

Duncan, H. F., Smith, A. J., Fleming, G. J. P., & Cooper, P. R. (2016). Epigenetic modulation of dental pulp stem cells: Implications for regenerative endodontics. International Endodontic Journal, 49(5), 431-446. doi: 10.1111/iej.12475

Hadis, M. A., Zainal, S. A., Holder, M. J., Carroll, J. D., Cooper, P. R., Milward, M. R., & Palin, W. M. (2016). The dark art of light measurement: Accurate radiometry for low-level light therapy. Lasers in Medical Science, 31(4), 789-809. doi: 10.1007/s10103-016-1914-y

2015

Chapter in Book - Research

Smith, A. J., & Cooper, P. R. (2015). Cellular signaling in dentin repair and regeneration. In A. Vishwakarma, P. Sharpe, S. Shi & M. Ramalingam (Eds.), Stem cell biology and tissue engineering in dental sciences. (pp. 405-417). London, UK: Elsevier. doi: 10.1016/B978-0-12-397157-9.00036-9

Journal - Research Article

Zhang, J., Wang, Z., Jiang, Y., Niu, Z., Fu, L., Luo, Z., Cooper, P. R., … He, W. (2015). Nuclear Factor I-C promotes proliferation and differentiation of apical papilla-derived human stem cells in vitro. Experimental Cell Research, 332(2), 259-266. doi: 10.1016/j.yexcr.2015.01.020

Wang, Z., Ma, F., Wang, J., Zhou, Z., Liu, B., He, X., … Cooper, P. R. (2015). Extracellular signal-regulated kinase mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling are required for lipopolysaccharide-mediated mineralization in murine odontoblast-like cells. Journal of Endodontics, 41(6), 871-876. doi: 10.1016/j.joen.2015.01.006

Andreev, P. S., Coates, M. I., Shelton, R. M., Cooper, P. R., Smith, M. P., & Sansom, I. J. (2015). Upper Ordovician chondrichthyan-like scales from North America. Palaeontology, 58(4), 691-704. doi: 10.1111/pala.12167

Davies, O. G., Cooper, P. R., Shelton, R. M., Smith, A. J., & Scheven, B. A. (2015). Isolation of adipose and bone marrow mesenchymal stem cells using CD29 and CD90 modifies their capacity for osteogenic and adipogenic differentiation. Journal of Tissue Engineering, 6, 1-10. doi: 10.1177/2041731415592356

Spengler, J., Lugonja, B., Ytterberg, A. J., Zubarev, R. A., Creese, A. J., Pearson, M. J., … Cooper, P. R., … Scheel-Toellner, D. (2015). Release of active peptidyl arginine deiminases by neutrophils can explain production of extracellular citrullinated autoantigens in rheumatoid arthritis synovial fluid. Arthritis & Rheumatology, 67(12), 3135-3145. doi: 10.1002/art.39313

He, W., Wang, Z., Luo, Z., Yu, Q., Jiang, Y., Zhang, Y., … Cooper, P. R. (2015). LPS promote the odontoblastic differentiation of human dental pulp stem cells via MAPK signaling pathway. Journal of Cellular Physiology, 230(3), 554-561. doi: 10.1002/jcp.24732

Davies, O. G., Cooper, P. R., Shelton, R. M., Smith, A. J., & Scheven, B. A. (2015). A comparison of the in vitro mineralisation and dentinogenic potential of mesenchymal stem cells derived from adipose tissue, bone marrow and dental pulp. Journal of Bone & Mineral Metabolism, 33(4), 371-382. doi: 10.1007/s00774-014-0601-y

Journal - Research Other

Duncan, H. F., Smith, A. J., Fleming, G. J. P., Moran, G. P., & Cooper, P. R. (2015). Transcriptional profiling of suberoylanilide hydroxamic acid (SAHA) regulated genes in mineralizing dental pulp cells at early and late time points. Genomics Data, 5, 391-393. doi: 10.1016/j.gdata.2015.07.013

Farges, J.-C., Alliot-Licht, B., Renard, E., Ducret, M., Gaudin, A., Smith, A. J., & Cooper, P. R. (2015). Dental pulp defence and repair mechanisms in dental caries. Mediators of Inflammation, 2015, 230251. doi: 10.1155/2015/230251

Smith, J. G., Smith, A. J., Shelton, R. M., & Cooper, P. R. (2015). Dental pulp cell behavior in biomimetic environments [Research report]. Journal of Dental Research, 94(11), 1552-1559. doi: 10.1177/0022034515599767

Conference Contribution - Published proceedings: Full paper

Palin, W. M., Hadis, M. A., Milward, M. R., Carroll, J. D., & Cooper, P. R. (2015). Beam profile measurements for dental phototherapy: The effect of distance, wavelength and tissue thickness. Proceedings of SPIE (Vol. 9309): Mechanisms for Low-Light Therapy X. 9309, 930905. doi: 10.1117/12.2077628

Hadis, M. A., Cooper, P. R., Milward, M. R., Gorecki, P., Tarte, E., Churm, J., & Palin, W. M. (2015). The effect of UV-Vis to near-infrared light on the biological response of human dental pulp cells. Proceedings of SPIE (Vol. 9309): Mechanisms for Low-Light Therapy X. 9309, 930906. doi: 10.1117/12.2077645

Milward, M. R., Hadis, M. A., Cooper, P. R., Gorecki, P., Carroll, J. D., & Palin, W. M. (2015). Biomodulatory effects of laser irradiation on dental pulp cells in vitro. Proceedings of SPIE (Vol. 9309): Mechanisms for Low-Light Therapy X. 930908. doi: 10.1117/12.2077717

2014

Chapter in Book - Research

Cooper, P. R., & Smith, A. J. (2014). Inflammatory processes in the dental pulp. In M. Goldberg (Ed.), The dental pulp: Biology, pathology, and regenerative therapies. (pp. 97-112). Berlin, Germany: Springer. doi: 10.1007/978-3-642-55160-4_7

Journal - Research Article

He, W., Wang, Z., Zhou, Z., Zhang, Y., Zhu, Q., Wei, K., … Cooper, P. R., … Yu, Q. (2014). Lipopolysaccharide enhances Wnt5a expression through toll-like receptor 4, myeloid differentiating factor 88, phosphatidylinositol 3-OH kinase/AKT and nuclear factor kappa B pathways in human dental pulp stem cells. Journal of Endodontics, 40(1), 69-75. doi: 10.1016/j.joen.2013.09.011

Li, D., Fu, L., Zhang, Y., Yu, Q., Ma, F., Wang, Z., … Cooper, P. R., & He, W. (2014). The effects of LPS on adhesion and migration of human dental pulp stem cells in vitro. Journal of Dentistry, 42(10), 1327-1334. doi: 10.1016/j.jdent.2014.07.007

Macedo, R. G., Robinson, J. P., Verhaagen, B., Walmsley, A. D., Versluis, M., Cooper, P. R., & van der Sluis, L. W. M. (2014). A novel methodology providing insights into removal of biofilm-mimicking hydrogel from lateral morphological features of the root canal during irrigation procedures. International Endodontic Journal, 47(11), 1040-1051. doi: 10.1111/iej.12246

He, W., Zhang, J., Niu, Z., Yu, Q., Wang, Z., Zhang, R., … Cooper, P. R. (2014). Regulatory interplay between NFIC and TGF-β1 in apical papilla-derived stem cells. Journal of Dental Research, 93(5), 496-501. doi: 10.1177/0022034514525200

Nicolae, L. C., Shelton, R. M., Cooper, P. R., Martin, R. A., & Palin, W. M. (2014). The effect of Bioglass addition on mechanical and physical properties of photoactive UDMA-TEGDMA resin composites. Key Engineering Materials, 587, 215-221. doi: 10.4028/www.scientific.net/KEM.587.215

Milward, M. R., Holder, M. J., Palin, W. M., Hadis, M. A., Carroll, J. D., & Cooper, P. R. (2014). Low Level Light Therapy (LLLT) for the treatment and management of dental and oral diseases. Dental Update, 41(9), 763-772. doi: 10.12968/denu.2014.41.9.763

Yu, Y., Wang, L., Yu, J., Lei, G., Yan, M., Smith, G., Cooper, P. R., … Smith, A. J. (2014). Dentin matrix proteins (DMPs) enhance differentiation of BMMSCs via ERK and P38 MAPK pathways. Cell & Tissue Research, 356(1), 171-182. doi: 10.1007/s00441-013-1790-8

Asif, I. M., Shelton, R. M., Cooper, P. R., Addison, O., & Martin, R. A. (2014). In vitro bioactivity of titanium-doped bioglass. Journal of Materials Science: Materials in Medicine, 25(8), 1865-1873. doi: 10.1007/s10856-014-5230-4

Journal - Research Other

Davies, O. G., Smith, A. J., Cooper, P. R., Shelton, R. M., & Scheven, B. A. (2014). The effects of cryopreservation on cells isolated from adipose, bone marrow and dental pulp tissues [Brief communication]. Cryobiology, 69(2), 342-347. doi: 10.1016/j.cryobiol.2014.08.003

Carroll, J. D., Milward, M. R., Cooper, P. R., Hadis, M., & Palin, W. M. (2014). Developments in low level light therapy (LLLT) for dentistry. Dental Materials, 30(5), 465-475. doi: 10.1016/j.dental.2014.02.006

Conference Contribution - Published proceedings: Full paper

Cooper, P. R., Holder, M. J., & Smith, A. J. (2014). Inflammation and regeneration in the dentin-pulp complex: A double-edged sword. Journal of Endodontics, 40(4, Suppl.), (pp. S46-S51). doi: 10.1016/j.joen.2014.01.021

2013

Journal - Research Article

Tomson, P. L., Lumley, P. J., Alexander, M. Y., Smith, A. J., & Cooper, P. R. (2013). Hepatocyte growth factor is sequestered in dentine matrix and promotes regeneration-associated events in dental pulp cells. Cytokine, 61(2), 622-629. doi: 10.1016/j.cyto.2012.11.009

Robinson, J. P., Lumley, P. J., Cooper, P. R., Grover, L. M., & Walmsley, A. D. (2013). Reciprocating root canal technique induces greater debris accumulation than a continuous rotary technique as assessed by 3-dimensional micro-computed tomography. Journal of Endodontics, 39(8), 1067-1070. doi: 10.1016/j.joen.2013.04.003

Zhang, J., Zhang, Y., Lv, H., Yu, Q., Zhou, Z., Zhu, Q., … Cooper, P. R., … He, W. (2013). Human stem cells from the apical papilla response to bacterial lipopolysaccharide exposure and anti-inflammatory effects of nuclear factor I C. Journal of Endodontics, 39(11), 1416-1422. doi: 10.1016/j.joen.2013.07.018

Duncan, H. F., Smith, A. J., Fleming, G. J. P., & Cooper, P. R. (2013). Histone deacetylase inhibitors epigenetically promote reparative events in primary dental pulp cells. Experimental Cell Research, 319(10), 1534-1543. doi: 10.1016/j.yexcr.2013.02.022

Zhang, J., Zhu, Q. L., Huang, P., Yu, Q., Wang, Z. H., Cooper, P. R., … He, W. (2013). CpG ODN-induced matrix metalloproteinase-13 expression is mediated via activation of the ERK and NF-κB signalling pathways in odontoblast cells. International Endodontic Journal, 46(7), 666-674. doi: 10.1111/iej.12043

Cooper, P. R., Palmer, L. J., & Chapple, I. L. C. (2013). Neutrophil extracellular traps as a new paradigm in innate immunity: Friend or foe? Periodontology 2000, 63(1), 165-197. doi: 10.1111/prd.12025

Milward, M. R., Chapple, I. L. C., Carter, K., Matthews, J. B., & Cooper, P. R. (2013). Micronutrient modulation of NF-κB in oral keratinocytes exposed to periodontal bacteria. Innate Immunity, 19(2), 140-151. doi: 10.1177/1753425912454761

Ferracane, J. L., Cooper, P. R., & Smith, A. J. (2013). Dentin matrix component solubilization by solutions at pH relevant to self-etching dental adhesives. Journal of Adhesive Dentistry, 15(5), 407-412. doi: 10.3290/j.jad.a29536

Lei, G., Yu, Y., Jiang, Y., Wang, S., Yan, M., Smith, A. J., … Cooper, P. R., … Yu, J. (2013). Differentiation of BMMSCs into odontoblast-like cells induced by natural dentine matrix. Archives of Oral Biology, 58(7), 862-870. doi: 10.1016/j.archoralbio.2013.01.002

2012

Chapter in Book - Research

Simon, S., Smith, A. J., Lumley, P. J., Cooper, P. R., & Berdal, A. (2012). The pulp healing process: From generation to regeneration. In H. Larjava (Ed.), Oral wound healing: Cell biology and clinical management. (pp. 313-332). Oxford, UK: Wiley Blackwell. doi: 10.1002/9781118704509.ch13

Journal - Research Article

Smith, A. J., Smith, J. G., Shelton, R. M., & Cooper, P. R. (2012). Harnessing the natural regenerative potential of the dental pulp. Dental Clinics of North America, 56(3), 589-601. doi: 10.1016/j.cden.2012.05.011

Gale, Z., Cooper, P. R., & Scheven, B. A. (2012). Glial cell line-derived neurotrophic factor influences proliferation of osteoblastic cells. Cytokine, 57(2), 276-281. doi: 10.1016/j.cyto.2011.10.023

Robinson, J. P., Lumley, P. J., Claridge, E., Cooper, P. R., Grover, L. M., Williams, R. L., & Walmsley, A. D. (2012). An analytical Micro CT methodology for quantifying inorganic dentine debris following internal tooth preparation. Journal of Dentistry, 40(11), 999-1005. doi: 10.1016/j.jdent.2012.08.007

Duncan, H. F., Smith, A. J., Fleming, G. J. P., & Cooper, P. R. (2012). Histone deacetylase inhibitors induced differentiation and accelerated mineralization of pulp-derived cells. Journal of Endodontics, 38(3), 339-345. doi: 10.1016/j.joen.2011.12.014

Man, J., Shelton, R. M., Cooper, P. R., & Scheven, B. A. (2012). Low-intensity low-frequency ultrasound promotes proliferation and differentiation of odontoblast-like cells. Journal of Endodontics, 38(5), 608-613. doi: 10.1016/j.joen.2012.01.015

Smith, J. G., Smith, A. J., Shelton, R. M., & Cooper, P. R. (2012). Recruitment of dental pulp cells by dentine and pulp extracellular matrix components. Experimental Cell Research, 318(18), 2397-2406. doi: 10.1016/j.yexcr.2012.07.008

Palmer, L. J., Cooper, P. R., Ling, M. R., Wright, H. J., Huissoon, A., & Chapple, I. L. C. (2012). Hypochlorous acid regulates neutrophil extracellular trap release in humans. Clinical & Experimental Immunology, 167(2), 261-268. doi: 10.1111/j.1365-2249.2011.04518.x

Smith, J. G., Smith, A. J., Shelton, R. M., & Cooper, P. R. (2012). Antibacterial activity of dentine and pulp extracellular matrix extracts. International Endodontic Journal, 45(8), 749-755. doi: 10.1111/j.1365-2591.2012.02031.x

Palmer, L. J., Chapple, I. L. C., Wright, H. J., Roberts, A., & Cooper, P. R. (2012). Extracellular deoxyribonuclease production by periodontal bacteria. Journal of Periodontal Research, 47(4), 439-445. doi: 10.1111/j.1600-0765.2011.01451.x

Holder, M. J., Milward, M. R., Palin, W. M., Hadis, M. A., & Cooper, P. R. (2012). Effects of red light-emitting diode irradiation on dental pulp cells. Journal of Dental Research, 91(10), 961-966. doi: 10.1177/0022034512456040

Khan, E., Shelton, R. M., Cooper, P. R., Hamburger, J., & Landini, G. (2012). Architectural characterization of Organotypic cultures of H400 and primary rat keratinocytes. Journal of Biomedical Materials Research Part A, 100A(12), 3227-3238. doi: 10.1002/jbm.a.34263

Journal - Research Other

Man, J., Shelton, R. M., Cooper, P. R., Landini, G., & Scheven, B. A. (2012). Low intensity ultrasound stimulates osteoblast migration at different frequencies [Short communication]. Journal of Bone & Mineral Metabolism, 30(5), 602-607. doi: 10.1007/s00774-012-0368-y

Smith, A. J., Scheven, B. A., Takahashi, Y., Ferracane, J. L., Shelton, R. M., & Cooper, P. R. (2012). Dentine as a bioactive extracellular matrix. Archives of Oral Biology, 57(2), 109-121. doi: 10.1016/j.archoralbio.2011.07.008

2011

Chapter in Book - Research

Simon, S., Cooper, P., & Berdal, I. A. (2011). Tissue engineering and endodontics. In J. Ferri & E. B. Hunziker (Eds.), Preprosthetic and maxillofacial surgery: Biomaterials, bone grafting and tissue engineering. (pp. 336-362). Cambridge, UK: Woodhead. doi: 10.1016/B978-1-84569-589-7.50018-3

Journal - Research Article

Zhang, R., Cooper, P. R., Smith, G., Nör, J. E., & Smith, A. J. (2011). Angiogenic activity of dentin matrix components. Journal of Endodontics, 37(1), 26-30. doi: 10.1016/j.joen.2010.08.042

Wright, H. J., Chapple, I. L. C., Matthews, J. B., & Cooper, P. R. (2011). Fusobacterium nucleatum regulation of neutrophil transcription. Journal of Periodontal Research, 46(1), 1-12. doi: 10.1111/j.1600-0765.2010.01299.x

Simon, S. R. J., Berdal, A., Cooper, P. R., Lumley, P. J., Tomson, P. L., & Smith, A. J. (2011). Dentin-pulp complex regeneration: From lab to clinic. Advances in Dental Research, 23(3), 340-345. doi: 10.1177/0022034511405327

Cooper, P. R., McLachlan, J. L., Simon, S., Graham, L. W., & Smith, A. J. (2011). Mediators of inflammation and regeneration. Advances in Dental Research, 23(3), 290-295. doi: 10.1177/0022034511405389

Duncan, H. F., Smith, A. J., Fleming, G. J. P., & Cooper, P. R. (2011). HDACi: Cellular effects, opportunities for restorative dentistry. Journal of Dental Research, 90(12), 1377-1388. doi: 10.1177/0022034511406919

Gale, Z., Cooper, P. R., & Scheven, B. A. A. (2011). Effects of glial cell line-derived neurotrophic factor on dental pulp cells. Journal of Dental Research, 90(10), 1240-1245. doi: 10.1177/0022034511417443

Journal - Research Other

Holder, M. J., & Cooper, P. R. (2011). Species identification and authentification of human and rodent cell cultures using polymerase chain reaction analysis of vomeronasal receptor genes [Brief report]. Cytotechnology, 63(6), 553-558. doi: 10.1007/s10616-011-9394-1

Conference Contribution - Published proceedings: Abstract

Tomson, P. L., Lumley, P. J., Yan, J., Alexander, M. Y., Smith, A. J., & Cooper, P. R. (2011). Pulp capping agents release hepatocyte growth factor from dentine which may contribute to mineralised tissue repair in the dentine-pulp complex [Extended abstract]. European Cells & Materials, 22(Suppl. 2), (pp. 95). [Abstract]

2010

Journal - Research Article

Simon, S., Smith, A. J., Berdal, A., Lumley, P. J., & Cooper, P. R. (2010). The MAP kinase pathway is involved in odontoblast stimulation via p38 phosphorylation. Journal of Endodontics, 36(2), 256-259. doi: 10.1016/j.joen.2009.09.019

Musson, D. S., McLachlan, J. L., Sloan, A. J., Smith, A. J., & Cooper, P. R. (2010). Adrenomedullin is expressed during rodent dental tissue development and promotes cell growth and mineralization. Biology of the Cell, 102(3), 145-157. doi: 10.1042/BC20090122

Wylie, C. M., Davenport, A. J., Cooper, P. R., & Shelton, R. M. (2010). Oral keratinocyte responses to nickel-based dental casting alloys in vitro. Journal of Biomaterials Applications, 25(3), 251-267. doi: 10.1177/0885328209349870

Journal - Research Other

Cooper, P. R., Takahashi, Y., Graham, L. W., Simon, S., Imazato, S., & Smith, A. J. (2010). Inflammation-regeneration interplay in the dentine-pulp complex. Journal of Dentistry, 38(9), 687-697. doi: 10.1016/j.jdent.2010.05.016

Simon, S., Lumley, P. J., Cooper, P. R., Berdal, A., Machtou, P., & Smith, A. J. (2010). Trauma and dentinogenesis: A case report. Journal of Endodontics, 36(2), 342-344. doi: 10.1016/j.joen.2009.09.021

Ferracane, J. L., Cooper, P. R., & Smith, A. J. (2010). Can interaction of materials with the dentin-pulp complex contribute to dentin regeneration? Odontology, 98(1), 2-14. doi: 10.1007/s10266-009-0116-5

2009

Journal - Research Article

Simon, S., Smith, A. J., Lumley, P. J., Berdal, A., Smith, G., Finney, S., & Cooper, P. R. (2009). Molecular characterization of young and mature odontoblasts. Bone, 45(4), 693-703. doi: 10.1016/j.bone.2009.06.018

Scheven, B. A. A., Shelton, R. M., Cooper, P. R., Walmsley, A. D., & Smith, A. J. (2009). Therapeutic ultrasound for dental tissue repair. Medical Hypotheses, 73(4), 591-593. doi: 10.1016/j.mehy.2009.05.032

Baker, S. M., Sugars, R. V., Wendel, M., Smith, A. J., Waddington, R. J., Cooper, P. R., & Sloan, A. J. (2009). TGF-β/extracellular matrix interactions in dentin matrix: A role in regulating sequestration and protection of bioactivity. Calcified Tissue International, 85(1), 66-74. doi: 10.1007/s00223-009-9248-4

Scheven, B. A., Man, J., Millard, J. L., Cooper, P. R., Lea, S. C., Walmsley, A. D., & Smith, A. J. (2009). VEGF and odontoblast-like cells: Stimulation by low frequency ultrasound. Archives of Oral Biology, 54(2), 185-191. doi: 10.1016/j.archoralbio.2008.09.008

Patel, M., Smith, A. J., Sloan, A. J., Smith, G., & Cooper, P. R. (2009). Phenotype and behaviour of dental pulp cells during expansion culture. Archives of Oral Biology, 54(10), 898-908. doi: 10.1016/j.archoralbio.2009.06.008

2008

Journal - Research Article

Fleming, G. J. P., Awan, M., Cooper, P. R., & Sloan, A. J. (2008). The potential of a resin-composite to be cured to a 4 mm depth. Dental Materials, 24(4), 522-529. doi: 10.1016/j.dental.2007.05.016

Simon, S., Cooper, P., Smith, A., Picard, B., Naulin Ifi, C., & Berdal, A. (2008). Evaluation of a new laboratory model for pulp healing: Preliminary study. International Endodontic Journal, 41(9), 781-790. doi: 10.1111/j.1365-2591.2008.01433.x

Wright, H. J., Matthews, J. B., Chapple, I. L. C., Ling-Mountford, N., & Cooper, P. R. (2008). Periodontitis associates with a type 1 IFN signature in peripheral blood neutrophils. Journal of Immunology, 181(8), 5775-5784. doi: 10.4049/jimmunol.181.8.5775

Journal - Research Other

Smith, A. J., Lumley, P. J., Tomson, P. L., & Cooper, P. R. (2008). Dental regeneration and materials: A partnership. Clinical Oral Investigations, 12(2), 103-108. doi: 10.1007/s00784-008-0189-5

Conference Contribution - Published proceedings: Full paper

Liu, Y., Barralet, J., Cooper, P., & Shelton, R. (2008). Effects of octacalcium phosphate on the development of bone marrow derived stromal cells: Comparison of osteogenic medium/OCP induced osteocalcin expression. Key Engineering Materials, II, (pp. 1009-1012). [Full Paper]

2007

Journal - Research Article

Liu, Y., Cooper, P. R., Barralet, J. E., & Shelton, R. M. (2007). Influence of calcium phosphate crystal assemblies on the proliferation and osteogenic gene expression of rat bone marrow stromal cells. Biomaterials, 28(7), 1393-1403. doi: 10.1016/j.biomaterials.2006.11.019

Tomson, P. L., Grover, L. M., Lumley, P. J., Sloan, A. J., Smith, A. J., & Cooper, P. R. (2007). Dissolution of bio-active dentine matrix components by mineral trioxide aggregate. Journal of Dentistry, 35(8), 636-642. doi: 10.1016/j.jdent.2007.04.008

Scheven, B. A., Millard, J. L., Cooper, P. R., Lea, S. C., Walmsley, A. D., & Smith, A. J. (2007). Short-term in vitro effects of low frequency ultrasound on odontoblast-like cells. Ultrasound in Medicine & Biology, 33(9), 1475-1482. doi: 10.1016/j.ultrasmedbio.2007.03.010

Matthews, J. B., Wright, H. J., Roberts, A., Cooper, P. R., & Chapple, I. L. C. (2007). Hyperactivity and reactivity of peripheral blood neutrophils in chronic periodontitis. Clinical & Experimental Immunology, 147(2), 255-264. doi: 10.1111/j.1365-2249.2006.03276.x

Milward, M. R., Chapple, I. L. C., Wright, H. J., Millard, J. L., Matthews, J. B., & Cooper, P. R. (2007). Differential activation of NF-κB and gene expression in oral epithelial cells by periodontal pathogens. Clinical & Experimental Immunology, 148(2), 307-324. doi: 10.1111/j.1365-2249.2007.03342.x

Milward, M. R., & Cooper, P. R. (2007). Competency assessment for infection control in the undergraduate dental curriculum. European Journal of Dental Education, 11(3), 148-154. doi: 10.1111/j.1600-0579.2007.00439.x

Journal - Research Other

Matthews, J. B., Wright, H. J., Roberts, A., Ling-Mountford, N., Cooper, P. R., & Chapple, I. L. C. (2007). Neutrophil hyper-responsiveness in periodontitis. Journal of Dental Research, 86(8), 718-722. doi: 10.1177/154405910708600806

2006

Journal - Research Article

Graham, L., Cooper, P. R., Cassidy, N., Nor, J. E., Sloan, A. J., & Smith, A. J. (2006). The effect of calcium hydroxide on solubilisation of bio-active dentine matrix components. Biomaterials, 27(14), 2865-2873. doi: 10.1016/j.biomaterials.2005.12.020

Shelton, R. M., Liu, Y., Cooper, P. R., Gbureck, U., German, M. J., & Barralet, J. E. (2006). Bone marrow cell gene expression and tissue construct assembly using octacalcium phosphate microscaffolds. Biomaterials, 27(14), 2874-2881. doi: 10.1016/j.biomaterials.2005.12.031

Wright, H. J., Chapple, I. L. C., Cooper, P., & Matthews, J. B. (2006). Platelet-derived growth factor (PDGF) isoform and PDGF receptor expression in drug-induced gingival overgrowth and hereditary gingival fibrosis. Oral Diseases, 12(3), 315-323. doi: 10.1111/j.1601-0825.2005.01201.x

2005

Journal - Research Article

McLachlan, J. L., Smith, A. J., Bujalska, I. J., & Cooper, P. R. (2005). Gene expression profiling of pulpal tissue reveals the molecular complexity of dental caries. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1741(3), 271-281. doi: 10.1016/j.bbadis.2005.03.007

Dhopatkar, A. A., Sloan, A. J., Rock, W. P., Cooper, P. R., & Smith, A. J. (2005). British Orthodontic Society, Chapman Prize Winner 2003: A novel in vitro culture model to investigate the reaction of the dentine-pulp complex to orthodontic force. Journal of Orthodontics, 32(2), 122-132. doi: 10.1179/146531205225020979

Milward, M., & Cooper, P. (2005). Periodontal disease and the ageing patient. Dental Update, 32(10), 598-600, 602-604. doi: 10.12968/denu.2005.32.10.598

Barralet, J. E., Wang, L., Lawson, M., Triffitt, J. T., Cooper, P. R., & Shelton, R. M. (2005). Comparison of bone marrow cell growth on 2D and 3D alginate hydrogels. Journal of Materials Science: Materials in Medicine, 16(6), 515-519. doi: 10.1007/s10856-005-0526-z

2004

Journal - Research Article

McLachlan, J. L., Sloan, A. J., Smith, A. J., Landini, G., & Cooper, P. R. (2004). S100 and cytokine expression in caries. Infection & Immunity, 72(7), 4102-4108. doi: 10.1128/IAI.72.7.4102-4108.2004

2003

Journal - Research Article

McLachlan, J. L., Smith, A. J., Sloan, A. J., & Cooper, P. R. (2003). Gene expression analysis in cells of the dentine-pulp complex in healthy and carious teeth. Archives of Oral Biology, 48(4), 273-283. doi: 10.1016/S0003-9969(03)00003-7

Wang, L., Shelton, R. M., Cooper, P. R., Lawson, M., Triffitt, J. T., & Barralet, J. E. (2003). Evaluation of sodium alginate for bone marrow cell tissue engineering. Biomaterials, 24(20), 3475-3481. doi: 10.1016/S0142-9612(03)00167-4

Journal - Research Other

McLachlan, J. L., Smith, A. J., & Cooper, P. R. (2003). Piezo-power microdissection of mature human dental tissue [Short communication]. Archives of Oral Biology, 48(10), 731-736. doi: 10.1016/S0003-9969(03)00152-3

2001

Journal - Research Article

Caldwell, G. M., Eddy, R. L., Day, C. D., Haley, L. H., Cooper, P. R., Sait, S. S. J., … Shows, T. B. (2001). Mapping of genes and transcribed sequences in a gene rich 400-kb region on human chromosome 11p15.1 → p14. Cytogenetics & Cell Genetics, 92(1-2), 103-107. doi: 10.1159/000056877

Cooper, P., Potter, S., Mueck, B., Yousefi, S., & Jarai, G. (2001). Identification of genes induced by inflammatory cytokines in airway epithelium. American Journal of Physiology: Lung Cellular & Molecular Physiology, 280(5), L841-L852. doi: 10.1152/ajplung.2001.280.5.L841

Yousefi, S., Cooper, P. R., Potter, S. L., Mueck, B., & Jarai, G. (2001). Cloning and expression analysis of a novel G-protein-coupled receptor selectively expressed on granulocytes. Journal of Leukocyte Biology, 69(6), 1045-1052. doi: 10.1189/jlb.69.6.1045

2000

Journal - Research Article

Cooper, P., Mueck, B., Yousefi, S., Potter, S., & Jarai, G. (2000). cDNA-RDA of genes expressed in fetal and adult lungs identifies factors important in development and function. American Journal of Physiology: Lung Cellular & Molecular Physiology, 278(2), L284-L293. doi: 10.1152/ajplung.2000.278.2.L284

Yousefi, S., Cooper, P. R., Mueck, B., Potter, S. L., & Jarai, G. (2000). cDNA representational difference analysis of human neutrophils stimulated by GM-CSF. Biochemical & Biophysical Research Communications, 277(2), 401-409. doi: 10.1006/bbrc.2000.3678

1999

Journal - Research Article

Smilinich, N. J., Day, C. D., Fitzpatrick, G. V., Caldwell, G. M., Lossie, A. C., Cooper, P. R., … Higgins, M. J. (1999). A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome. PNAS, 96(14), 8064-8069. doi: 10.1073/pnas.96.14.8064

1998

Journal - Research Article

Varon, R., Vissinga, C., Platzer, M., Cerosaletti, K. M., Chrzanowska, K. H., Saar, K., … Cooper, P. R., … Reis, A. (1998). Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell, 93(3), 467-476. doi: 10.1016/S0092-8674(00)81174-5

Cooper, P. R., Smilinich, N. J., Day, C. D., Nowak, N. J., Reid, L. H., Pearsall, R. S., … Higgins, M. J. (1998). Divergently transcribed overlapping genes expressed in liver and kidney and located in the 11p15.5 imprinted domain. Genomics, 49(1), 38-51. doi: 10.1006/geno.1998.5221

Cooper, P. R., Nowak, N. J., Higgins, M. J., Church, D. M., & Shows, T. B. (1998). Transcript mapping of the human chromosome 11q12-q13.1 gene-rich region identifies several newly described conserved genes. Genomics, 49(3), 419-429. doi: 10.1006/geno.1998.5291

Journal - Research Other

Stöhr, H., Marquardt, A., Rivera, A., Cooper, P. R., Nowak, N. J., Shows, T. B., … Weber, B. H. F. (1998). A gene map of the Best's vitelliform macular dystrophy region in chromosome 11q12-q13.1. Genome Research, 8(1), 48-56. doi: 10.1101/gr.8.1.48

Higgins, M. J., Day, C. D., Smilinich, N. J., Ni, L., Cooper, P. R., Nowak, N. J., … Shows, T. (1998). Contig maps and genomic sequencing identify candidate genes in the usher 1C locus. Genome Research, 8(1), 57-68. doi: 10.1101/gr.8.1.57

1997

Journal - Research Article

Stankovic, T., Byrd, P. J., Cooper, P. R., McConville, C. M., Munroe, D. J., Riley, J. H., … Taylor, A. M. R. (1997). Construction of a transcription map around the gene for ataxia telangiectasia: Identification of at least four novel genes. Genomics, 40(2), 267-276. doi: 10.1006/geno.1996.4595

Cooper, P. R., Nowak, N. J., Higgins, M. J., Simpson, S. A., Marquardt, A., Stoehr, H., … Shows, T. B. (1997). A sequence-ready high-resolution physical map of the best macular dystrophy gene region in 11q12-q13. Genomics, 41(2), 185-192. doi: 10.1006/geno.1997.4660

Reid, L. H., Davies, C., Cooper, P. R., Crider-Miller, S. J., Sait, S. N. J., Nowak, N. J., … Higgins, M. J. (1997). A 1-Mb physical map and PAC contig of the imprinted domain in 11p15.5 that contains TAPA1 and the BWSCR1/WT2 region. Genomics, 43(3), 366-375. doi: 10.1006/geno.1997.4826

Journal - Research Other

Byrd, P. J., Stankovic, T., McConville, C. M., Smith, A. D., Cooper, P. R., & Taylor, A. M. R. (1997). Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23. Genome Research, 7(1), 71-75. doi: 10.1101/gr.7.1.71

1996

Journal - Research Article

Byrd, P. J., McConville, C. M., Cooper, P., Parkhill, J., Stankovic, T., McGuire, G. M., … Taylor, A. M. R. (1996). Mutations revealed by sequencing the 5′ half of the gene for ataxia telangiectasia. Human Molecular Genetics, 5(1), 145-149. doi: 10.1093/hmg/5.1.145

Byrd, P. J., Cooper, P. R., Stankovic, T., Kullar, H. S., Watts, G. D. J., Robinson, P. J., & Taylor, A. M. R. (1996). A gene transcribed from the bidirectional ATM promoter coding for a serine rich protein: Amino acid sequence, structure and expression studies. Human Molecular Genetics, 5(11), 1785-1791. doi: 10.1093/hmg/5.11.1785

1994

Journal - Research Article

Ambrose, H. J., Byrd, P. J., McConville, C. M., Cooper, P. R., Stankovic, T., Riley, J. H., … Taylor, A. M. R. (1994). A physical map across chromosome 11q22-q23 containing the major locus for ataxia telangiectasia. Genomics, 21(3), 612-619. doi: 10.1006/geno.1994.1321