Maternal & Fetal Health Research Group
This research group covers both maternal and fetal health and outcome.
Ongoing data is collected for both the (i) Fetal Medicine clinical unit which reviews women with complicated fetal problems or those at risk for them, and the (ii) Maternal Medical clinic where women attend with underlying medical problems. This enables not only audit, but followup of specific cases.
Investigation into Preeclampsia
Preeclampsia is a condition which develops in pregnancy, and involves severe maternal systemic complications including hypertension, liver and renal dysfunction, together with fetal effects such as severe growth restriction secondary to placental dysfunction. It is a common condition in pregnancy (2-3% pregnancies), and it is the main cause for elective preterm delivery. The group is involved in 2 large studies focusing on these areas
- Prediction of outcome (mother and neonate)
- Assessment of proteinuria as screening/diagnostic test.
Participation in Multicentre Clinical Trials
The following randomised controlled clinical trials the group is/are planning to participate in:
- PROMPT trial (premature rupture membranes and timing of delivery) Primary centre (Sydney)
- NIFTY trial (Ongoing maintenance tocolysis with nifedipine in threatened preterm labour identified by positive fibronectin screening) (Auckland)
- PACT trial (progesterone preventative therapy for women with a history of early preterm delivery) (Adelaide)
- MIG trial (comparing metformin and insulin therapy for gestational diabetes treatment). Primary centre (Auckland)