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Horsfield Laboratory: Chromosome Structure and Development

Associate Professor Julia Horsfield's group is studying how packaging of chromosomes in cells affects the function of genes that are involved in cancer, or how that influences early stages of embryo development.

Their tools for discovery include the cool and amazing zebrafish animal model and human cancer cell lines, with the main research focus seeking to understand the regulation of gene expression by cohesin and related proteins, which are also required for sister chromatid cohesion during mitosis. To do most of the research, the group is using the genetically amenable vertebrate animal model, the zebrafish, utilising the Otago Zebrafish Facility.

Learn more about the Chromosome Structure and Development group.

Key people

Associate Professor Julia Horsfield (Principal Investigator)

Dr Jisha Antony

Dr Trent Newman

Dr Megan Leask

Bryony Leeke

Tanushree Dasgupta

Noel Jhinku

Judith Marsman

Michael Meier

Amarni Thomas