Professor Mik Black

Contact Details
- Phone
- +64 3 479 7831
- mik.black@otago.ac.nz
University Links
- Position
- Professor
- Department
- Department of Biochemistry
- Qualifications
- BSc(Hons) MS PhD
- Research summary
- Bioinformatics, cancer genomics, data science, statistics
- Teaching
- BIOC352, GENE315, GENE360, GENE412, STAT435, QGEN401, BIOC461
Research
Professor Black is a member of the Centre for Translational Cancer Research, and his research focuses on the development of methods for the analysis of genomic data, with a strong emphasis on cancer and other human diseases. A common theme is the use of techniques that allow high-dimensional and often very disparate data sets to be combined in ways that provide new insights into disease development and progression:
Centre for Translational Cancer Research
This research is highly collaborative, and Mik works closely with a number of Otago research groups, as well as with long-standing national and international collaborators at the University of Auckland, the Institute of Environmental Science and Research, Wake Forest University Medical School, and Moffitt Cancer Center.
In addition to his own work, Mik has been heavily involved in establishing national research infrastructure in high performance computing through the NZ eScience Infrastructure, and in genomics and bioinformatics through Genomics Aotearoa, where he is the Chair of the Bioinformatics Leadership Team:
NZ eScience Infrastructure
Genomics Aotearoa
Publications
McGuinness, C. F., Black, M. A., & Dunbier, A. K. (2023). Restriction site associated DNA sequencing for tumour mutation burden estimation and mutation signature analysis. Cancer Medicine. Advance online publication. doi: 10.1002/cam4.6711
Te Aika, B., Liggins, L., Rye, C., Perkins, E. O., Huh, J., Brauning, R., Godfery, T., & Black, M. A. (2023). Aotearoa genomic data repository: An āhuru mōwai for taonga species sequencing data. Molecular Ecology Resources, 13866. Advance online publication. doi: 10.1111/1755-0998.13866
Yang, Z., Guarracino, A., Biggs, P. J., Black, M. A., Ismail, N., Wold, J. R., Merriman, T. R., … de Ligt, J. (2023). Pangenome graphs in infectious disease: A comprehensive genetic variation analysis of Neisseria meningitidis leveraging Oxford Nanopore long reads. Frontiers in Genetics, 14, 1225248. doi: 10.3389/fgene.2023.1225248
Taylor, M. F., Black, M. A., Hampton, M. B., & Ledgerwood, E. C. (2023). Insights into H2O2-induced signaling in Jurkat cells from analysis of gene expression. Free Radical Research. Advance online publication. doi: 10.1080/10715762.2023.2165073
Mehta, S., Wright, D., Black, M. A., Merrie, A., Anjomshoaa, A., Munro, F., Reeve, A., McCall, J., & Print, C. (2022). Impact of clinical data veracity on cancer genomic research. JNCI Cancer Spectrum. doi: 10.1093/jncics/pkac070
McGuinness, C. F., Black, M. A., & Dunbier, A. K. (2023). Restriction site associated DNA sequencing for tumour mutation burden estimation and mutation signature analysis. Cancer Medicine. Advance online publication. doi: 10.1002/cam4.6711
Journal - Research Article
Taylor, M. F., Black, M. A., Hampton, M. B., & Ledgerwood, E. C. (2023). Insights into H2O2-induced signaling in Jurkat cells from analysis of gene expression. Free Radical Research. Advance online publication. doi: 10.1080/10715762.2023.2165073
Journal - Research Article
Te Aika, B., Liggins, L., Rye, C., Perkins, E. O., Huh, J., Brauning, R., Godfery, T., & Black, M. A. (2023). Aotearoa genomic data repository: An āhuru mōwai for taonga species sequencing data. Molecular Ecology Resources, 13866. Advance online publication. doi: 10.1111/1755-0998.13866
Journal - Research Article
Yang, Z., Guarracino, A., Biggs, P. J., Black, M. A., Ismail, N., Wold, J. R., Merriman, T. R., … de Ligt, J. (2023). Pangenome graphs in infectious disease: A comprehensive genetic variation analysis of Neisseria meningitidis leveraging Oxford Nanopore long reads. Frontiers in Genetics, 14, 1225248. doi: 10.3389/fgene.2023.1225248
Journal - Research Article
Bougen-Zhukov, N., Decourtye-Espiard, L., Mitchell, W., Redpath, K., Perkinson, J., Godwin, T., Black, M. A., & Guilford, P. (2022). E-cadherin-deficient cells are sensitive to the multikinase inhibitor dasatinib. Cancers, 14, 1609. doi: 10.3390/cancers14071609
Journal - Research Article
Gardner, P. P., Paterson, J. M., McGimpsey, S., Ashari-Ghomi, F., Umu, S. U., Pawlik, A., Gavryushkin, A., & Black, M. A. (2022). Sustained software development, not number of citations or journal choice, is indicative of accurate bioinformatic software. Genome Biology, 23, 56. doi: 10.1186/s13059-022-02625-x
Journal - Research Article
Mehta, S., Wright, D., Black, M. A., Merrie, A., Anjomshoaa, A., Munro, F., Reeve, A., McCall, J., & Print, C. (2022). Impact of clinical data veracity on cancer genomic research. JNCI Cancer Spectrum. doi: 10.1093/jncics/pkac070
Journal - Research Article
Aiderus, A., Newberg, J. Y., Guzman-Rojas, L., Contreras-Sandoval, A. M., Meshey, A. L., Jones, D. J., … Black, M. A., … Mann, M. B. (2021). Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression. PLoS Genetics, 17(8), e1009094. doi: 10.1371/journal.pgen.1009094
Journal - Research Article
Decourtye-Espiard, L., Bougen-Zhukov, N., Godwin, T., Brew, T., Schulpen, E., Black, M. A., & Guilford, P. (2021). E-cadherin-deficient epithelial cells are sensitive to HDAC inhibitors. Cancers, 14(1), 175. doi: 10.3390/ cancers14010102
Journal - Research Article
Muradova, E., Patel, N., Sell, B., Bittencourt, B. B., Ojeda, S. S., Adelmann, C. H., … Black, M. A., … Tsai, K. Y. (2021). Non-invasive assessment of epidermal genomic markers of UV exposure in skin. Journal of Investigative Dermatology, 141(1), 124-131.e2. doi: 10.1016/j.jid.2020.05.093
Journal - Research Article
Pinkney, H. R., Black, M. A., & Diermeier, S. D. (2021). Single-cell RNA-seq reveals heterogeneous lncRNA expression in xenografted triple-negative breast cancer cells. Biology, 10(10), 987. doi: 10.3390/biology10100987
Journal - Research Article
Pullikuth, A. K., Routh, E. D., Zimmermann, K. D., Chifman, J., Chou, J. W., Soike, M. H., … Black, M. A., … Miller, L. D. (2021). Bulk and single-cell profiling of breast tumors identifies TREM-1 as a dominant immune suppressive marker associated with poor outcomes. Frontiers in Oncology, 11, 734959. doi: 10.3389/fonc.2021.734959
Journal - Research Article
Wiggins, G. A. R., Black, M. A., Dunbier, A., Merriman, T. R., Pearson, J. F., & Walker, L. C. (2021). Variable expression quantitative trait loci analysis of breast cancer risk variants. Scientific Reports, 11(1), 7192. doi: 10.1038/s41598-021-86690-5
Journal - Research Article
Wiggins, G. A. R., Black, M. A., Dunbier, A., Morley-Bunker, A. E., kConFab Investigators, Pearson, J. F., & Walker, L. C. (2021). Increased gene expression variability in BRCA1-associated and basal-like breast tumours. Breast Cancer Research & Treatment, 189, 363-375. doi: 10.1007/s10549-021-06328-y
Journal - Research Article
Eom, J., Park, S. M., Feisst, V., Chen, C.-J. J., Mathy, J. E., McIntosh, J. D., … Black, M. A., … Dunbar, P. R. (2020). Distinctive subpopulations of stromal cells are present in human lymph nodes infiltrated with melanoma. Cancer Immunology Research, 8(8), 1-14. doi: 10.1158/2326-6066.Cir-19-0796
Journal - Research Article
Lasham, A., Fitzgerald, S. J., Knowlton, N., Robb, T., Tsai, P., Black, M. A., … Mehta, S. Y., Harris, G., … Print, C. G. (2020). A predictor of early disease recurrence in patients with breast cancer using a cell-free RNA and protein liquid biopsy. Clinical Breast Cancer, 20(2), 108-116. doi: 10.1016/j.clbc.2019.07.003
Journal - Research Article
Zou, D., Day, R., Cocadiz, J. A., Parackal, S., Mitchell, W., Black, M. A., … Jackson, C., & Guilford, P. (2020). Circulating tumor DNA is a sensitive marker for routine monitoring of treatment response in advanced colorectal cancer. Carcinogenesis, 41(11), 1507-1517. doi: 10.1093/carcin/bgaa102
Journal - Research Article
Bougen-Zhukov, N., Nouri, Y., Godwin, T., Taylor, M., Hakkaart, C., Single, A., Brew, T., Permina, E., Chen, A., Black, M. A., & Guilford, P. (2019). Allosteric AKT inhibitors target synthetic lethal vulnerabilities in E-cadherin-deficient cells. Cancers, 11(9), 1359. doi: 10.3390/cancers11091359
Journal - Research Article
Godwin, T. D., Kelly, S. T., Brew, T. P., Bougen-Zhukov, N. M., Single, A. B., Chen, A., Stylianou, C. E., … Currie, S. K., Telford, B. J., Beetham, H. G., … Black, M. A., & Guilford, P. J. (2019). E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function. Gastric Cancer, 22(2), 273-286. doi: 10.1007/s10120-018-0859-1
Journal - Research Article
Norton, S. E., Ward-Hartstonge, K. A., McCall, J. L., Leman, J. K. H., Taylor, E. S., Munro, F., Black, M. A., … Kemp, R. A. (2019). High-dimensional mass cytometric analysis reveals an increase in effector regulatory T cells as a distinguishing feature of colorectal tumors. Journal of Immunology, 202, 1871-1884. doi: 10.4049/jimmunol.1801368
Journal - Research Article
Parackal, S., Zou, D., Day, R., Black, M., & Guilford, P. (2019). Comparison of Roche Cell-Free DNA collection Tubes® to Streck Cell-Free DNA BCT®s for sample stability using healthy volunteers. Practical Laboratory Medicine, 16, e00125. doi: 10.1016/j.plabm.2019.e00125
Journal - Research Article
Todd, E. V., Ortega-Recalde, O., Liu, H., Lamm, M. S., Rutherford, K. M., Cross, H., Black, M. A., Kardailsky, O., … Hore, T. A., … Gemmell, N. J. (2019). Stress, novel sex genes, and epigenetic reprogramming orchestrate socially controlled sex change. Science Advances, 5(7), eaaw7006. doi: 10.1126/sciadv.aaw7006
Journal - Research Article
Aiderus, A., Black, M. A., & Dunbier, A. K. (2018). Fatty acid oxidation is associated with proliferation and prognosis in breast and other cancers. BMC Cancer, 18, 805. doi: 10.1186/s12885-018-4626-9
Journal - Research Article
Bilton, T. P., Schofield, M. R., Black, M. A., Chagné, D., Wilcox, P. L., & Dodds, K. G. (2018). Accounting for errors in low coverage high-throughput sequencing data when constructing genetic maps using biparental outcrossed populations. Genetics, 209(1), 65-76. doi: 10.1534/genetics.117.300627
Journal - Research Article
Campbell, H., Fleming, N., Roth, I., Mehta, S., Wiles, A., Williams, G., … Munro, F., McNoe, L., Black, M., McCall, J., Slatter, T. L., … Braithwaite, A. W. (2018). Δ133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling. Nature Communications, 9(1), 254. doi: 10.1038/s41467-017-02408-0
Journal - Research Article
Craig, H. J. B., Stachowicz, K., Black, M., Parry, M., Burke, C. R., Meier, S., & Amer, P. R. (2018). Genotype by environment interactions in fertility traits in New Zealand dairy cows. Journal of Dairy Science, 101, 10991-11003. doi: 10.3168/jds.2017-14195
Journal - Research Article
Lacey, C. J., Doudney, K., Bridgman, P. G., George, P. M., Mulder, R. T., Zarifeh, J. J., Kimber, B., Cadzow, M. J., Black, M. A., Merriman, T. R., … Pearson, J. F., Cameron, V. A., & Kennedy, M. A. (2018). Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy. Scientific Reports, 8, 7548. doi: 10.1038/s41598-018-25827-5
Journal - Research Article
Lawrence, B., Blenkiron, C., Parker, K., Tsai, P., Fitzgerald, S., Shields, P., … Black, M., … Robinson, B., … Carroll, R., … Morrin, H., … Jackson, C., … Print, C. (2018). Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer. npj Genomic Medicine, 3, 18. doi: 10.1038/s41525-018-0058-3
Journal - Research Article
Lee, S. L. J., Horsfield, J. A., Black, M. A., Rutherford, K., & Gemmell, N. J. (2018). Identification of sex differences in zebrafish (Danio rerio) brains during early sexual differentiation and masculinisation using 17α-methyltestoterone. Biology of Reproduction, 99(2), 446-460. doi: 10.1093/biolre/iox175
Journal - Research Article
Newberg, J. Y., Black, M. A., Jenkins, N. A., Copeland, N. G., Mann, K. M., & Mann, M. B. (2018). SB Driver Analysis: A Sleeping Beauty cancer driver analysis framework for identifying and prioritizing experimentally actionable oncogenes and tumor suppressors. Nucleic Acids Research, 45(16), e94. doi: 10.1093/nar/gky450
Journal - Research Article
Stovall, W. R., Taylor, H. R., Black, M., Grosser, S., Rutherford, K., & Gemmell, N. J. (2018). Genetic sex assignment in wild populations using genotyping‐by‐sequencing data: A statistical threshold approach. Molecular Ecology Resources, 18(2), 179-190. doi: 10.1111/1755-0998.12767
Journal - Research Article
Taylor, E. S., McCall, J. L., Shen, S., Girardin, A., Munro, F. M., Black, M. A., Ward-Hartstonge, K. A., & Kemp, R. A. (2018). Prognostic roles for IL-2-producing and CD69+ T cell subsets in colorectal cancer patients. International Journal of Cancer, 143(8), 2008-2016. doi: 10.1002/ijc.31598
Journal - Research Article
Thomas, A., Routh, E. D., Pullikuth, A., Jin, G., Su, J., Chou, J. W., … Black, M. A., … Miller, L. D. (2018). Tumor mutational burden is a determinant of immune-mediated survival in breast cancer. OncoImmunology, 7(10), e1490854. doi: 10.1080/2162402X.2018.1490854
Journal - Research Article
Tomek, P., Gore, S. K., Potts, C. L., Print, C. G., Black, M. A., Hallermayr, A., … Ching, L.-M. (2018). Imprinted and ancient gene: A potential mediator of cancer cell survival during tryptophan deprivation. Cell Communication & Signaling, 16, 88. doi: 10.1186/s12964-018-0301-7
Journal - Research Article
Ariazi, E. A., Taylor, J. C., Black, M. A., Nicolas, E., Slifker, M. J., Azzam, D. J., & Boyd, J. (2017). A new role for ERα: Silencing via DNA methylation of basal, stem cell, and EMT genes. Molecular Cancer Research, 15(2). doi: 10.1158/1541-7786.mcr-16-0283
Journal - Research Article
Lee, S. L. J., Horsfield, J. A., Black, M. A., Rutherford, K., Fisher, A., & Gemmell, N. J. (2017). Histological and transcriptomic effects of 17α-methyltestosterone on zebrafish gonad development. BMC Genomics, 18, 557. doi: 10.1186/s12864-017-3915-z
Journal - Research Article
McInnes, T., Zou, D., Rao, D. S., Munro, F. M., Phillips, V. L., McCall, J. L., Black, M. A., Reeve, A. E., & Guilford, P. J. (2017). Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer. BMC Cancer, 17, 228. doi: 10.1186/s12885-017-3226-4
Journal - Research Article
Muthukaruppan, A., Lasham, A., Blenkiron, C., Woad, K. J., Black, M. A., Knowlton, N., … Shelling, A. N. (2017). Gene expression profling of breast tumours from New Zealand patients. New Zealand Medical Journal, 130(1464), 40-56. Retrieved from http://www.nzma.org.nz/journal
Journal - Research Article
Muthukaruppan, A., Lasham, A., Woad, K. J., Black, M. A., Blenkiron, C., Miller, L. D., Harris, G., … Findlay, M. P., … Print, C. G. (2017). Multimodal assessment of estrogen receptor mRNA profiles to quantify estrogen pathway activity in breast tumors. Clinical Breast Cancer, 17(2), 139-153. doi: 10.1016/j.clbc.2016.09.001
Journal - Research Article
Cadzow, M., Merriman, T. R., Boocock, J., Dalbeth, N., Stamp, L. K., Black, M. A., … Wilcox, P. L. (2016). Lack of direct evidence for natural selection at the candidate thrifty gene locus, PPARGC1A. BMC Medical Genetics, 17, 80. doi: 10.1186/s12881-016-0341-z
Journal - Research Article
Jenkins, G. M., Goddard, M. E., Black, M. A., Brauning, R., Auvray, B., Dodds, K. G., … McEwan, J. C. (2016). Copy number variants in the sheep genome detected using multiple approaches. BMC Genomics, 17, 441. doi: 10.1186/s12864-016-2754-7
Journal - Research Article
Mann, K. M., Newberg, J. Y., Black, M. A., Jones, D. J., Amaya-Manzanares, F., Guzman-Rojas, L., … McNoe, L. A., Selvanesan, L., … Mann, M. B. (2016). Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq. Nature Biotechnology, 34(9), 962-972. doi: 10.1038/nbt.3637
Journal - Research Article
Miller, L. D., Chou, J. A., Black, M. A., Print, C., Chifman, J., Alistar, A., … Marincola, F. M. (2016). Immunogenic subtypes of breast cancer delineated by gene classifiers of immune responsiveness. Cancer Immunology Research, 4(7). doi: 10.1158/2326-6066.cir-15-0149
Journal - Research Article
Nguyen, H. T., Boocock, J., Merriman, T. R., & Black, M. A. (2016). SRBreak: A read-depth and split-read framework to identify breakpoints of different events inside simple copy-number variable regions. Frontiers in Genetics, 7, 160. doi: 10.3389/fgene.2016.00160
Journal - Research Article
Rangel, R., Lee, S.-C., Ban, K. H.-K., Guzman-Rojas, L., Mann, M. B., Newberg, J. Y., … McNoe, L. A., Selvanesan, L., … Black, M. A., … Copeland, N. G. (2016). Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression. PNAS, 113(48), E7749-E7758. doi: 10.1073/pnas.1613859113
Journal - Research Article
Smith, L. M., Parr-Brownlie, L. C., Duncan, E. J., Black, M. A., Gemmell, N. J., Dearden, P. K., & Reynolds, J. N. J. (2016). Striatal mRNA expression patterns underlying peak dose L-DOPA-induced dyskinesia in the 6-OHDA hemiparkinsonian rat. Neuroscience, 324, 238-251. doi: 10.1016/j.neuroscience.2016.03.012
Journal - Research Article
Taylor, E. S., McCall, J. L., Girardin, A., Munro, F. M., Black, M. A., & Kemp, R. A. (2016). Functional impairment of infiltrating T cells in human colorectal cancer. OncoImmunology, 5(11), e1234573. doi: 10.1080/2162402X.2016.1234573
Journal - Research Article
Todd, E. V., Black, M. A., & Gemmell, N. J. (2016). The power and promise of RNA-seq in ecology and evolution. Molecular Ecology, 25(6), 1224-1241. doi: 10.1111/mec.13526
Journal - Research Article
Ahmadi, O., Stringer, M. D., Black, M. A., & McCall, J. L. (2015). Clinico-pathological factors influencing lymph node yield in colorectal cancer and impact on survival: Analysis of New Zealand Cancer Registry data. Journal of Surgical Oncology, 11(4), 451-458. doi: 10.1002/jso.23848
Journal - Research Article
Boocock, J., Chagné, D., Merriman, T. R., & Black, M. A. (2015). The distribution and impact of common copy-number variation in the genome of the domesticated apple, Malus x domestica Borkh. BMC Genomics, 16(1), 848. doi: 10.1186/s12864-015-2096-x
Journal - Research Article
Liu, H., Lamm, M. S., Rutherford, K., Black, M. A., Godwin, J. R., & Gemmell, N. J. (2015). Large-scale transcriptome sequencing reveals novel expression patterns for key sex-related genes in a sex-changing fish. Biology of Sex Differences, 6, 26. doi: 10.1186/s13293-015-0044-8
Journal - Research Article
Mann, M. B., Black, M. A., Jones, D. J., Ward, J. M., Yew, C. C. K., Newberg, J. Y., … Jenkins, N. A. (2015). Transposon mutagenesis identifies genetic drivers of BrafV600E melanoma. Nature Genetics, 47(5), 486-495. doi: 10.1038/ng.3275
Journal - Research Article
Sawaya, S., Boocock, J., Black, M. A., & Gemmell, N. J. (2015). Exploring possible DNA structures in real-time polymerase kinetics using Pacific Biosciences sequencer data. BMC Bioinformatics, 16, 21. doi: 10.1186/s12859-014-0449-0
Journal - Research Article
Topless, R. K., Flynn, T. J., Cadzow, M., Stamp, L. K., Dalbeth, N., Black, M. A., & Merriman, T. R. (2015). Association of SLC2A9 genotype with phenotypic variability of serum urate in pre-menopausal women. Frontiers in Genetics, 6, 313. doi: 10.3389/fgene.2015.00313
Journal - Research Article
Ahmadi, O., Stringer, M. D., Black, M. A., & McCall, J. L. (2014). Influence of age and site of disease on lymph node yield in colorectal cancer. New Zealand Medical Journal, 127(1395). Retrieved from http://www.nzma.org.nz/journal
Journal - Research Article
Alistar, A., Chou, J. W., Nagalla, S., Black, M. A., D'Agostino, R., & Miller, L. (2014). Dual roles for immune metagenes in breast cancer prognosis and therapy prediction. Genome Medicine, 6(10), 80. doi: 10.1186/s13073-014-0080-8
Journal - Research Article
Batt, C., Phipps-Green, A. J., Black, M. A., Cadzow, M., Merriman, M. E., Topless, R., … Harrison, A., Highton, J., … Stamp, L., … Merriman, T. R. (2014). Sugar-sweetened beverage consumption: A risk factor for prevalent gout with SLC2A9 genotype-specific effects on serum urate and risk of gout. Annals of the Rheumatic Diseases, 73(12), 2101-2106. doi: 10.1136/annrheumdis-2013-203600
Journal - Research Article
Cadzow, M., Boocock, J., Nguyen, H. T., Wilcox, P., Merriman, T. R., & Black, M. A. (2014). A bioinformatics workflow for detecting signatures of selection in genomic data. Frontiers in Genetics, 5, 293. doi: 10.3389/fgene.2014.00293
Journal - Research Article
Chen, A., Beetham, H., Black, M. A., Priya, R., Telford, B. J., Guest, J., Wiggins, G. A. R., Godwin, T. D., … Guilford, P. J. (2014). E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition. BMC Cancer, 14, 552. doi: 10.1186/1471-2407-14-552
Journal - Research Article
Dubouzet, J. G., Donaldson, L., Black, M. A., McNoe, L., Liu, V., & Lloyd-Jones, G. (2014). Heterologous hybridisation to a Pinus microarray: Profiling of gene expression in Pinus radiata saplings exposed to ethephon. New Zealand Journal of Forestry Science, 44, 21. doi: 10.1186/s40490-014-0021-8
Journal - Research Article
Kenny, L. C., Black, M. A., Poston, L., Taylor, R., Myers, J. E., Baker, P. N., … North, R. A. (2014). Early pregnancy prediction of preeclampsia in nulliparous women, combining clinical risk and biomarkers: The Screening for Pregnancy Endpoints (SCOPE) international cohort study. Hypertension, 64(3), 644-652. doi: 10.1161/hypertensionaha.114.03578
Journal - Research Article
Nguyen, H. T., Merriman, T. R., & Black, M. A. (2014). The CNVrd2 package: Measurement of copy number at complex loci using high-throughput sequencing data. Frontiers in Genetics, 5, 248. doi: 10.3389/fgene.2014.00248
Journal - Research Article
Roberts, R. L., Wallace, M. C., Wright, D. F. B., Cadzow, M., Dalbeth, N., Jones, P. B., Stamp, L. K., Harrison, A. A., Black, M. A., & Merriman, T. R. (2014). Frequency of CYP2C9 polymorphisms in Polynesian people and potential relevance to management of gout with benzbromarone. Joint Bone Spine, 81(2), 160-163. doi: 10.1016/j.jbspin.2013.07.006
Journal - Research Article
Tannock, G. W., Taylor, C., Lawley, B., Loach, D., Gould, M., Dunn, A. C., McLellan, A. D., Black, M. A., McNoe, L., Dekker, J., … Collett, M. A. (2014). Altered transcription of murine genes induced in the small bowel by administration of probiotic strain Lactobacillus rhamnosus HN001. Applied & Environmental Microbiology, 80(9), 2851-2859. doi: 10.1128/aem.00336-14
Journal - Research Article
Butler, M. I., Stockwell, P. A., Black, M. A., Day, R. C., Lamont, I. L., & Poulter, R. T. M. (2013). Pseudomonas syringae pv. actinidiae from recent outbreaks of kiwifruit bacterial canker belong to different clones that originated in China. PLoS ONE, 8(2), e57464. doi: 10.1371/journal.pone.0057464
Journal - Research Article
Cappello, S., Gray, M. J., Badouel, C., Lange, S., Einsiedler, M., Srour, M., … Jenkins, Z. A., Morgan, T., Preitner, N., … Black, M. A., Markie, D., … Robertson, S. P. (2013). Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development. Nature Genetics, 45(11), 1300-1308. doi: 10.1038/ng.2765
Journal - Research Article
Girardin, A., McCall, J., Black, M. A., Edwards, F., Phillips, V., Taylor, E. S., Reeve, A. E., & Kemp, R. A. (2013). Inflammatory and regulatory T cells contribute to a unique immune microenvironment in tumor tissue of colorectal cancer patients. International Journal of Cancer, 132(8), 1842-1850. doi: 10.1002/ijc.27855
Journal - Research Article
Nagalla, S., Chou, J. W., Willingham, M. C., Ruiz, J., Vaughn, J. P., Dubey, P., … Black, M. A., & Miller, L. D. (2013). Interactions between immunity, proliferation and molecular subtype in breast cancer prognosis. Genome Biology, 14, R34. doi: 10.1186/gb-2013-14-4-r34
Journal - Research Article
Sawaya, S., Bagshaw, A., Buschiazzo, E., Kumar, P., Chowdhury, S., Black, M. A., & Gemmell, N. (2013). Microsatellite tandem repeats are abundant in human promoters and are associated with regulatory elements. PLoS ONE, 8(2), e54710. doi: 10.1371/journal.pone.0054710
Journal - Research Article
tan Nguyen, H., Merriman, T. R., & Black, M. A. (2013). CNVrd, a read-depth algorithm for assigning copy-number at the FCGR Locus: Population-specific tagging of copy number variation at FCGR3B. PLoS ONE, 8(4), e63219. doi: 10.1371/journal.pone.0063219
Journal - Research Article
Trevarton, A. J., Mann, M. B., Knapp, C., Araki, H., Wren, J. D., Stones-Havas, S., Black, M. A., & Print, C. G. (2013). MelanomaDB: A web tool for integrative analysis of melanoma genomic information to identify disease-associated molecular pathways. Frontiers in Oncology, 3, 184. doi: 10.3389/fonc.2013.00184
Journal - Research Article
Xu, H., Black, M. A., & Craig, B. A. (2013). Evaluating accuracy of diagnostic tests with intermediate results in the absence of a gold standard. Statistics in Medicine, 32(15), 2571-2584. doi: 10.1002/sim.5695
Journal - Research Article
Caldon, C. E., Sergio, C. M., Kang, J., Muthukaruppan, A., Boersma, M. N., Stone, A., … Black, M. A., … Musgrove, E. A. (2012). Cyclin E2 overexpression is associated with endocrine resistance but not insensitivity to CDK2 inhibition in human breast cancer cells. Molecular Cancer Therapeutics, 11(7), 1488-1499. doi: 10.1158/1535-7163.mct-11-0963
Journal - Research Article
Debono, R., Topless, R., Markie, D., Black, M. A., & Merriman, T. R. (2012). Analysis of the DISC1 translocation partner (11q14.3) in genetic risk of schizophrenia. Genes, Brain & Behavior, 11(7), 859-963. doi: 10.1111/j.1601-183X.2012.00832.x
Journal - Research Article
Lasham, A., Samuel, W., Cao, H., Patel, R., Mehta, R., Stern, J. L., … Woolley, A. G., … Black, M. A., Shelling, A. N., Print, C. G., & Braithwaite, A. W. (2012). YB-1, the E2F Pathway, and regulation of tumor cell growth. Journal of the National Cancer Institute, 104(2), 133-146. doi: 10.1093/jnci/djr512
Journal - Research Article
Lee, Y. F., Miller, L. D., Chan, X. B., Black, M. A., Pang, B., Ong, C. W., … Desai, K. V. (2012). JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer. Breast Cancer Research, 14(3), R85. doi: 10.1186/bcr3200
Journal - Research Article
Mann, K. M., Ward, J. M., Yew, C. C. K., Kovochich, A., Dawson, D. W., Black, M. A., … Copeland, N. G. (2012). Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. PNAS, 109(16), 5934-5941. doi: 10.1073/pnas.1202490109
Journal - Research Article
Pilbrow, A. P., Folkersen, L., Pearson, J. F., Brown, C. M., McNoe, L., Wang, N. M., … Black, M. A., Troughton, R. W., Richards, A. M., … Cameron, V. A. (2012). The chromosome 9p21.3 coronary heart disease risk allele is associated with altered gene expression in normal heart and vascular tissues. PLoS ONE, 7(6), e39574. doi: 10.1371/journal.pone.0039574
Journal - Research Article
Wu, S. H., Black, M. A., North, R. A., & Rodrigo, A. G. (2012). A Bayesian model for classifying all differentially expressed proteins simultaneously in 2D PAGE gels. BMC Bioinformatics, 13, 137. doi: 10.1186/1471-2105-13-137
Journal - Research Article
Kalamorz, F., Keis, S., McMillan, D. G. G., Olsson, K., Stanton, J.-A., Stockwell, P., Black, M. A., … Cook, G. M. (2011). Draft genome sequence of the thermoalkaliphilic Caldalkalibacillus thermarum strain TA2.A1. Journal of Bacteriology, 193(16), 4290-4291. doi: 10.1128/jb.05035-11
Journal - Research Article
Kemp, R. A., Black, M. A., McCall, J., Yoon, H.-S., Phillips, V., Anjomshoaa, A., & Reeve, A. E. (2011). T cell subpopulations in lymph nodes may not be predictive of patient outcome in colorectal cancer. Journal of Experimental & Clinical Cancer Research, 30, 78. doi: 10.1186/1756-9966-30-78
Journal - Research Article
Linterman, K. S., Palmer, D. N., Kay, G. W., Barry, L. A., Mitchell, N. L., McFarlane, R. G., Black, M. A., … Hughes, S. M. (2011). Lentiviral-mediated gene transfer to the sheep brain: Implications for gene therapy in Batten disease. Human Gene Therapy, 22(8), 1011-1020. doi: 10.1089/hum.2011.026
Journal - Research Article
McCowan, L. M. E., North, R. A., Kho, E. M., Black, M. A., Chan, E. H. Y., & Dekker, G. A. (2011). Paternal contribution to small for gestational age babies: A multicenter prospective study. Obesity, 19(5), 1035-1039. doi: 10.1038/oby.2010.279
Journal - Research Article
Miller, L. D., Coffman, L. G., Chou, J. W., Black, M. A., Bergh, J., Agostino, Jr, R. D., … Torti, F. M. (2011). An iron regulatory gene signature predicts outcome in breast cancer. Cancer Research, 71(21), 6728-6737. doi: 10.1158/0008-5472.can-11-1870
Journal - Research Article
Nixon, G., Blattner, K., Dawson, J., Dovey, S., Black, M. A., Wilkins, G., Dunn, A. C., & McLellan, A. D. (2011). Streptokinase antibodies in patients presenting with acute coronary syndrome in three rural New Zealand populations. Journal of Clinical Pathology, 64, 426-429. doi: 10.1136/jcp.2010.085837
Journal - Research Article
North, R. A., McCowan, L. M. E., Dekker, G. A., Poston, L., Chan, E. H. Y., Stewart, A. W., Black, M. A., … Kenny, L. C. (2011). Clinical risk prediction for pre-eclampsia in nulliparous women: Development of model in international prospective cohort. BMJ, 342, d1875. doi: 10.1136/bmj.d1875
Journal - Research Article
Seed, P. T., Chappell, L. C., Black, M. A., Poppe, K. K., Hwang, Y.-C., Kasabov, N., … North, R. A. (2011). Prediction of preeclampsia and delivery of small for gestational age babies based on a combination of clinical risk factors in high-risk women. Hypertension in Pregnancy, 30(1), 58-73. doi: 10.3109/10641955.2010.486460
Journal - Research Article
Soon, W. W., Miller, L. D., Black, M. A., Dalmasso, C., Chan, X. B., Pang, B., … Liu, E. T. (2011). Combined genomic and phenotype screening reveals secretory factor SPINK1 as an invasion and survival factor associated with patient prognosis in breast cancer. EMBO Molecular Medicine, 3(8), 451-464. doi: 10.1002/emmm.201100150
Journal - Research Article
Ariazi, E. A., Brailoiu, E., Yerrum, S., Shupp, H. A., Slifker, M. J., Cunliffe, H. E., Black, M. A., … Jordan, V. C. (2010). The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells. Cancer Research, 70(3), 1184-1194. doi: 10.1158/0008-5472.CAN-09-3068
Journal - Research Article
Nasri, S., Anjomshoaa, A., Song, S., Guilford, P., McNoe, L., Black, M., Phillips, V., Reeve, A., & Humar, B. (2010). Oligonucleotide array outperforms SNP array on formalin-fixed paraffin-embedded clinical samples. Cancer Genetics & Cytogenetics, 198(1), 1-6. doi: 10.1016/j.cancergencyto.2009.12.002
Journal - Research Article
Anjomshoaa, A., Nasri, S., Humar, B., McCall, J. L., Chatterjee, A., Yoon, H.-S., McNoe, L., Black, M. A., & Reeve, A. E. (2009). Slow proliferation as a biological feature of colorectal cancer metastasis. British Journal of Cancer, 101(5), 822-828. doi: 10.1038/sj.bjc.6605229
Journal - Research Article
Atkinson, K. R., Blumenstein, M., Black, M. A., Wu, S. H., Kasabov, N., Taylor, R. S., … on behalf of the SCOPE Consortium. (2009). An altered pattern of circulating apolipoprotein E3 isoforms is implicated in preeclampsia. Journal of Lipid Research, 50, 71-80. doi: 10.1194/jlr.M800296-JLR200
Journal - Research Article
Blumenstein, M., McMaster, M. T., Black, M. A., Wu, S., Prakash, R., Cooney, J., … North, R. A. (2009). A proteomic approach identifies early pregnancy biomarkers for preeclampsia: Novel linkages between a predispositon to preeclampsia and cardiovascular disease. Proteomics, 9(11), 2929-2945. doi: 10.1002/pmic.200800625
Journal - Research Article
Jacobs, G. H., Chen, A., Stevens, S. G., Stockwell, P. A., Black, M. A., Tate, W. P., & Brown, C. M. (2009). Transterm: A database to aid the analysis of regulatory sequences in mRNAs. Nucleic Acids Research, 37(Database issue), D72-D76. doi: 10.1093/nar/gkn763
Journal - Research Article
Kho, E. M., McCowan, L. M. E., North, R. A., Roberts, C. T., Chan, E., Black, M. A., … on behalf of the SCOPE Consortium. (2009). Duration of sexual relationship and its effect on preeclampsia and small for gestational age perinatal outcome. Journal of Reproductive Immunology, 82(1), 66-73. doi: 10.1016/j.jri.2009.04.011
Journal - Research Article
Wu, S. H., Black, M. A., North, R. A., Atkinson, K. R., & Rodrigo, A. G. (2009). A statistical model to identify differentially expressed proteins in 2D PAGE gels. PLoS Computational Biology, 5(9), e1000509. doi: 10.1371/journal.pcbi.1000509
Journal - Research Article
Anjomshoaa, A., Lin, Y.-H., Black, M. A., McCall, J. L., Humar, B., Song, S., Fukuzawa, R., Yoon, H.-S., … van Rij, A., Thompson-Fawcett, M., & Reeve, A. E. (2008). Reduced expression of a gene proliferation signature is associated with enhanced malignancy in colon cancer. British Journal of Cancer, 99, 966-973. doi: 10.1038/sj.bjc.6604560
Journal - Research Article
John, T., Black, M. A., Toro, T. T., Leader, D., Gedye, C. A., Davis, I. D., Guilford, P. J., & Cebon, J. S. (2008). Predicting clinical outcome through molecular profiling in stage III melanoma. Clinical Cancer Research, 14(16), 5173-5180.
Journal - Research Article
Pilbrow, A. P., Ellmers, L. J., Black, M. A., Moravec, C. S., Sweet, W. E., Troughton, R. W., Richards, A. M., Frampton, C. M., & Cameron, V. A. (2008). Genomic selection of reference genes for real-time PCR in human myocardium. BMC Medical Genomics, 1, 64. doi: 10.1186/1755-8794-1-64
Journal - Research Article
Song, S., & Black, M. A. (2008). Microarray-based gene set analysis: A comparison of current methods. BMC Bioinformatics, 9, 502. doi: 10.1186/1471-2105-9-502
Journal - Research Article