Professor Kurt Krause

Torbati, E., Stuart, G., Krause, K., Brown, C., & Wise, L. (2023). Methods to assess chemokine binding and anti-chemotactic activity of virus proteins. In A. R. Lucas (Ed.), Chemokine-glycosaminoglycan interactions: Methods and protocols: Methods in molecular biology (Vol. 2597). (pp. 217-234). New York, N Y: Humana Press. doi: 10.1007/978-1-0716-2835-5_16

Chapter in Book - Research

Fagerlund, R. D., Ferguson, T. J., Maxwell, H. W. R., Opel-Reading, H. K., Krause, K. L., & Fineran, P. C. (2019). Reconstitution of CRISPR adaptation in vitro and its detection by PCR. In S. Bailey (Ed.), Methods in enzymology (Vol. 616: CRISPR-Cas enzymes). (pp. 411-433). Cambridge, MA: Academic Press. doi: 10.1016/bs.mie.2018.10.024

Chapter in Book - Research

Sharpe, M. L., Hastings, J. W., & Krause, K. L. (2014). Luciferases and light-emitting accessory proteins: Structural biology. In eLS. Chichester, UK: John Wiley & Sons. doi: 10.1002/9780470015902.a0003064.pub2

Chapter in Book - Research

Hastings, J. W., & Krause, K. L. (2006). Luciferases and light-emitting accessory proteins: Structural biology. In Encyclopedia of Life Sciences. New York: John Wiley & Sons. doi: 10.1038/npg.els.0003064

Chapter in Book - Research

Hastings, J. W., & Krause, K. L. (2005). Luciferase and light-emitting accessory proteins: Structural biology. In Encyclopedia of life sciences. John Wiley & Sons. doi: 10.1038/npg.els.0003064

Chapter in Book - Research

Krause, K. L., & Miller, M. D. (2002). A new engine for cleaving nucleic acid. In G. R. Eaton, D. C. Wiley & O. Jardetzky (Eds.), Structures and mechanisms: From ashes to enzymes. (pp. 270-293). Washington, DC, USA: American Chemical Society.

Chapter in Book - Research

Krause, K. L., & Miller, M. D. (2001). Using electrostatics to define the active site of Serratia endonuclease. In C. H. Schein (Ed.), Methods in molecular biology, Volume 160: Nuclease methods and protocols. (pp. 249-262). Totowa, NJ, USA: Humana Press.

Chapter in Book - Research

Hastings, J. W., & Krause, K. L. (2007). Luciferases and light-emitting accessory proteins: Structural biology. In Encyclopedia of Life Sciences. New York: John Wiley & Sons.

Chapter in Book - Other

Cooper, H. B., Krause, K. L., & Gardner, P. P. (2023). Finding priority bacterial ribosomes for future structural and antimicrobial research based upon global RNA and protein sequence analysis. PeerJ, 11, e14969. doi: 10.7717/peerj.14969

Journal - Research Article

Hards, K., Cheung, C.-Y., Waller, N., Adolph, C., Keighley, L., Tee, Z. S., Harold, L. K., Menorca, A., … Tyndall, J. D. A., McNeil, M. B., … Opel-Reading, H. K., Krause, K. L., … Berney, M., … Cook, G. M. (2022). An amiloride derivative is active against the F₁F_o-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis. Communications Biology, 5, 166. doi: 10.1038/s42003-022-03110-8

Journal - Research Article

Lawer, A., Tyler, C., Hards, K., Keighley, L. M., Cheung, C.-Y., Kierek, F., Su, S., … McInnes, T., Tyndall, J. D. A., Krause, K. L., Cook, G. M., & Gamble, A. B. (2022). Synthesis and biological evaluation of aurachin D analogues as inhibitors of Mycobacterium tuberculosis cytochrome bd Oxidase. ACS Medicinal Chemistry Letters. Advance online publication. doi: 10.1021/acsmedchemlett.2c00401

Journal - Research Article

Badart, M. P., Barnes, E. M., Cording, A. P., Gilmer, S. C. L., Billinghurst, I. D., Edupuganti, V. V. S. R., … Bland, A. R., Bower, R. L., Rana, Z., Ferguson, S. A., Opel Reading, H. K., Cook, G. M., Rosengren, R. J., Krause, K. L., Gamble, A. B., Ashton, J. C., & Hawkins, B. C. (2021). Synthesis and biological evaluation of (-) and (+)-spiroleucettadine and analogues. ChemMedChem, 16, 1308-1315. doi: 10.1002/cmdc.202000954

Journal - Research Article

Campbell, A. C., Tanner, J. J., & Krause, K. L. (2021). Optimisation of neuraminidase expression for use in drug discovery by using HEK293-6E cells. Viruses, 13, 1893. doi: 10.3390/v13101893

Journal - Research Article

Safarian, S., Opel-Reading, H. K., Wu, D., Mehdipour, A. R., Hards, K., Harold, L. K., … Stewart, I., … Cook, G. M., Krause, K. L., & Michel, H. (2021). The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB. Nature Communications, 12(1), 5236. doi: 10.1038/s41467-021-25537-z

Journal - Research Article

Kvach, M. V., Barzak, F. M., Harjes, S., Schares, H. A. M., Kurup, H. M., Jones, K. F., … Krause, K. L., … Filichev, V. (2020). Differential inhibition of APOBEC3 DNA-mutator isozymes by fluoro- versus non-fluoro-substituted 2'-deoxyzebularine embedded in single-stranded DNA. ChemBioChem, 21, 1028-1035. doi: 10.1002/cbic.201900505

Journal - Research Article

Murphy, E. L., Singh, K. V., Avila, B., Kleffmann, T., Gregory, S. T., Murray, B. E., Krause, K. L., … Jogl, G. (2020). Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis. Scientific Reports, 10, 16301. doi: 10.1038/s41598-020-73199-6

Journal - Research Article

Opel-Reading, H. K., Mortuza, R., & Krause, K. L. (2019). Detection of D-glutamate production from the dual function enzyme, 4-amino-4-deoxychorismate lyase/D-amino acid transaminase, in Mycobacterium smegmatis. Bio-protocol, 9(1), e3135. doi: 10.21769/BioProtoc.3135

Journal - Research Article

Mortuza, R., Aung, H. L., Taiaroa, G., Opel-Reading, H. K., Kleffmann, T., Cook, G. M., & Krause, K. L. (2018). Overexpression of a newly identified d-amino acid transaminase in Mycobacterium smegmatis complements glutamate racemase deletion. Molecular Microbiology, 107(2), 198-213. doi: 10.1111/mmi.13877

Journal - Research Article

Watkins, O. C., Sharpe, M. L., Perry, N. B., & Krause, K. L. (2018). New Zealand glowworm (Arachnocampa luminosa) bioluminescence is produced by a firefly-like luciferase but an entirely new luciferin. Scientific Reports, 8(3278). doi: 10.1038/s41598-018-21298-w

Journal - Research Article

Christensen, E. M., Patel, S. M., Korasick, D. A., Campbell, A. C., Krause, K. L., Becker, D. F., & Tanner, J. J. (2017). Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1. Journal of Biological Chemistry, 292(17), 7233-7243. doi: 10.1074/jbc.M117.780288

Journal - Research Article

Fagerlund, R. D., Wilkinson, M. E., Klykov, O., Barendregt, A., Pearce, F. G., Kieper, S. N., Maxwell, H. W. R., … Krause, K. L., Bostina, M., … Staals, R. H. J., & Fineran, P. C. (2017). Spacer capture and integration by a type I-F Cas1–Cas2-3 CRISPR adaptation complex. PNAS, 114(26), E5122-E5128. doi: 10.1073/pnas.1618421114

Journal - Research Article

Nakatani, Y., Opel-Reading, H. K., Merker, M., Machado, D., Andres, S., Kumar, S. S., … Aung, H. L., Cook, G. M., … Krause, K., & Köser, C. U. (2017). Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance. Antimicrobial Agents & Chemotherapy, 61(12), e01575-17. doi: 10.1128/aac.01575-17

Journal - Research Article

Poen, S., Nakatani, Y., Opel-Reading, H. K., Lassé, M., Dobson, R. C. J., & Krause, K. L. (2016). Exploring the structure of glutamate racemase from Mycobacterium tuberculosis as a template for anti-mycobacterial drug discovery. Biochemical Journal, 473, 1267-1280. doi: 10.1042/bcj20160186

Journal - Research Article

Sharif, S., Nakatani, Y., Wise, L., Corbett, M., Real, N. C., Stuart, G. S., Lateef, Z., Krause, K., Mercer, A. A., & Fleming, S. B. (2016). A broad-spectrum chemokine-binding protein of bovine papular stomatitis virus inhibits neutrophil and monocyte infiltration in inflammatory and wound models of mouse skin. PLoS ONE, 11(12), e0168007. doi: 10.1371/journal.pone.0168007

Journal - Research Article

Sowerby, S. J., Crump, J. A., Johnstone, M. C., Krause, K. L., & Hill, P. C. (2016). Smartphone microscopy of parasite eggs accumulated into a single field of view. American Journal of Tropical Medicine & Hygiene, 94(1), 227-230. doi: 10.4269/ajtmh.15-0427

Journal - Research Article

Wilkinson, M. E., Nakatani, Y., Staals, R. H. J., Kieper, S. N., Opel-Reading, H. K., McKenzie, R. E., Fineran, P. C., & Krause, K. L. (2016). Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR-Cas system. Biochemical Journal, 473, 1063-1072. doi: 10.1042/bcj20160078

Journal - Research Article

Couñago, R. M., Knapp, K. M., Nakatani, Y., Fleming, S. B., Corbett, M., Wise, L. M., Mercer, A. A., & Krause, K. L. (2015). Structures of orf virus chemokine binding protein in complex with host chemokines reveal clues to broad binding specificity. Structure, 23(7), 1199-1213. doi: 10.1016/j.str.2015.04.023

Journal - Research Article

Sharpe, M. L., Dearden, P. K., Gimenez, G., & Krause, K. L. (2015). Comparative RNA seq analysis of the New Zealand glowworm Arachnocampa luminosa reveals bioluminescence-related genes. BMC Genomics, 16, 825. doi: 10.1186/s12864-015-2006-2

Journal - Research Article

Davis, E., Scaletti-Hutchinson, E., Opel-Reading, H., Nakatani, Y., & Krause, K. L. (2014). The structure of alanine racemase from Acinetobacter baumannii. Acta Crystallographica Section F, 70(9), 1199-1205.

Journal - Research Article

Li, Y., Mortuza, R., Milligan, D. L., Tran, S. L., Strych, U., Cook, G. M., & Krause, K. L. (2014). Investigation of the essentiality of glutamate racemase in Mycobacterium smegmatis. Journal of Bacteriology, 196(24), 4239-4244. doi: 10.1128/jb.02090-14

Journal - Research Article

Baker, E. S., Luckner, S. R., Krause, K. L., Lambden, P. R., Clarke, I. N., & Ward, V. K. (2012). Inherent structural disorder and dimerisation of murine norovirus NS1-2 protein. PLoS ONE, 7(2), e30534. doi: 10.1371/journal.pone.0030534

Journal - Research Article

Scaletti, E. R., Luckner, S. R., & Krause, K. L. (2012). Structural features and kinetic characterization of alanine racemase from Staphylococcus aureus (Mu50). Acta Crystallographica Section D, 68, 82-92. doi: 10.1107/S0907444911050682

Journal - Research Article

Anthony, K. G., Strych, U., Yeung, K. R., Shoen, C. S., Perez, O., Krause, K. L., … Koski, R. A. (2011). New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis. PLoS ONE, 6(5), e20374. doi: 10.1371/journal.pone.0020374

Journal - Research Article

Im, H., Sharpe, M. L., Strych, U., Davlieva, M., & Krause, K. L. (2011). The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design. BMC Microbiology, 11, 116. doi: 10.1186/1471-2180-11-116

Journal - Research Article

Couñago, R. M., Fleming, S. B., Mercer, A. A., & Krause, K. L. (2010). Crystallization and preliminary X-ray analysis of the chemokine-binding protein from orf virus (Poxviridae). Acta Crystallographica Section F, F66, 819-823. doi: 10.1107/S1744309110018166

Journal - Research Article

Chen, C., Krause, K., & Pettitt, B. M. (2009). Advantage of being a dimer for Serratia marcescens endonuclease. Journal of Physical Chemistry B, 113(2), 511-521. doi: 10.1021/jp8057838

Journal - Research Article

Couñago, R. M., Davlieva, M., Strych, U., Hill, R. E., & Krause, K. L. (2009). Biochemical and structural characterization of alanine racemase from Bacillus anthracis (ames). BMC Structural Biology, 9, 53. doi: 10.1186/1472-6807-9-53

Journal - Research Article

Chen, C., Beck, B. W., Krause, K., Weksberg, T. E., & Pettitt, B. M. (2007). Effects of dimerization of Serratia marcescens endonuclease on water dynamics. Biopolymers, 85(3), 241-252.

Journal - Research Article

Milligan, D. L., Tran, S. L., Strych, U., Cook, G. M., & Krause, K. L. (2007). The alanine racemase of Mycobacterium smegmatis is essential for growth in the absence of D-alanine. Journal of Bacteriology, 189(22), 8381-8386.

Journal - Research Article

Strych, U., Davlieva, M., Longtin, J. P., Murphy, E. L., Im, H., Benedik, M. J., & Krause, K. L. (2007). Purification and preliminary crystallization of alanine racemase from Streptococcus pneumoniae. BMC Microbiology, 7, 40. doi: 10.1186/1471-2180-7-40

Journal - Research Article

Weksberg, T. E., Lynch, G. C., Krause, K. L., & Pettitt, B. M. (2007). Molecular dynamics simulations of Trichomonas vaginalis ferredoxin show a loop-cap transition. Biophysical Journal, 92(10), 3337-3345.

Journal - Research Article

LeMagueres, P., Im, H., Ebalunode, J., Strych, U., Benedik, M. J., Briggs, J. M., … Krause, K. L. (2005). The 1.9 Å crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site. Biochemistry, 44, 1471-1481.

Journal - Research Article

Shelburne, S. A., Visnegarwala, F., Adams, C., Krause, K. L., Hamill, R. J., & White, A. C. (2005). Unusual manifestations of disseminated Histoplasmosis in patients responding to antiretroviral therapy. American Journal of Medicine, 118, 1038-1041.

Journal - Research Article

Kim, M. G., Strych, U., Krause, K., Benedik, M., & Kohn, H. (2003). N(2)-substituted D,L-cycloserine derivatives: Synthesis and evaluation as alanine racemase inhibitors. Journal of Antibiotics, 56(2), 160-168.

Journal - Research Article

Kim, M. G., Strych, U., Krause, K., Benedik, M., & Kohn, H. (2003). Evaluation of amino-substituted heterocyclic derivatives as alanine racemase inhibitors. Medicinal Chemistry Research, 12(3), 130-138.

Journal - Research Article

LeMagueres, P., Im, H., Dvorak, A., Strych, U., Benedik, M., & Krause, K. L. (2003). Crystal structure at 1.45 Å resolution of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms. Biochemistry, 42(50), 14752-14761.

Journal - Research Article

Liu, L., Im, H., Cegielski, M., LeMagueres, P., Schultz, L. W., Krause, K. L., & Hastings, J. W. (2003). Characterization and crystallization of active domains of a novel luciferase from a marine dinoflagellate. Acta Crystallographica Section D, D59, 761-764.

Journal - Research Article

Vidakovic, M., Crossnoe, C. R., Neidre, C., Kim, K., Krause, K. L., & Germanas, J. P. (2003). Reactivity of reduced [2Fe-2S] Ferredoxins parallels host susceptibility to nitroimidazoles. Antimicrobial Agents & Chemotherapy, 47(1), 302-308.

Journal - Research Article

Crossnoe, C. R., Germanas, J. P., LeMagueres, P., Mustata, G., & Krause, K. L. (2002). The crystal structure of Trichomonas vaginalis ferredoxin provides insight into metronidazole activation. Journal of Molecular Biology, 318(2), 503-518.

Journal - Research Article

Musher, D. M., Dowell, M. E., Shortridge, V. D., Flamm, R. K., Jorgensen, J. H., Le Magueres, P., & Krause, K. L. (2002). Emergence of macrolide resistance during treatment of pneumococcal pneumonia. New England Journal of Medicine, 346(8), 630-631.

Journal - Research Article

Strych, U., Penland, R. L., Jimenez, M., Krause, K. L., & Benedik, M. J. (2001). Characterization of the alanine racemases from two Mycobacteria. FEMS Microbiology Letters, 196, 93-98.

Journal - Research Article

Strych, U., Huang, H. C., Krause, K. L., & Benedik, M. J. (2000). Characterization of the alanine racemases from Pseudomonas aeruginosa PAO1. Current Microbiology, 41, 290-294.

Journal - Research Article

Olivier, F., Roberts, S., Morris, A., Krause, K., & Baker, M. (2023). The arrival of Candida auris in Aotearoa NZ: Risk assessment and actions needed. The Briefing, (30 March). Retrieved from https://www.phcc.org.nz/briefing/arrival-candida-auris-aotearoa-nz-risk-assessment-and-actions-needed

Journal - Research Other

Torbati, E., Krause, K. L., & Ussher, J. E. (2021). The immune response to SARS-CoV-2 and variants of concern. Viruses, 13, 1911. doi: 10.3390/v13101911

Journal - Research Other

Krause, K. L., Furneaux, R., Benjes, P., Brimble, M., Davidson, T., Denny, W., … Ussher, J. E., & Ward, V. (2020). The post-lockdown period should be used to acquire effective therapies for future resurgence in SARS-Cov-2 infections. New Zealand Medical Journal, 133(1513), 107-111. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Other

McDonald, S. K., Matisoo-Smith, E. A., Buckley, H. R., Walter, R. K., Aung, H. L., Collins, C. J., Cook, G. M., Kardailsky, O., Krause, K., & Knapp, M. (2020). 'TB or not TB': The conundrum of pre-European contact tuberculosis in the Pacific. Philosophical Transactions of the Royal Society B, 375, 20190583. doi: 10.1098/rstb.2019.0583

Journal - Research Other

Chen, C., Beck, B. W., Krause, K., & Pettitt, B. M. (2006). Solvent participation in Serratia marcescens endonuclease complexes. Proteins, 62, 982-995.

Journal - Research Other

Krause, K. L. (2003). Review of the Nanotech 2003 - Nanotechnology Conference and Trade Show. IDrugs, 6(4), 309-311.

Journal - Research Other