Professor John Pickering

2026

Journal - Research Article

Monzel, M., Pickering, J. W., Condon, D. M., Beran, M. J., & Ebeyer, T. (2026). Reimagining the vividness of visual imagery questionnaire as a single item screener for aphantasia. Consciousness & Cognition, 142, 104061. doi: 10.1016/j.concog.2026.104061

Kavsak, P. A., Pickering, J. W., Strauß, B., Greenslade, J. H., Thießen, N., Haller, P. M., … Pemberton, C., Troughton, R., Richards, A. M., … Than, M. (2026). External validation of a universal laboratory pathway for early risk-stratification of myocardial infarction in the emergency setting. Canadian Journal of Cardiology. Advance online publication. doi: 10.1016/j.cjca.2026.04.023

Albert, A., Blume, L., Di Somma, S., Hur, M., Bellomo, R., Devarajan, P., … Pickering, J. W., … Albert, C. (2026). Difference of admission neutrophil gelatinase-associated lipocalin concentration between patients developing and not developing acute kidney injury or need for acute dialysis: An ancillary individual-study data meta-analysis (INDICATE–AKI). Kidney Medicine. Advance online publication. doi: 10.1016/j.xkme.2026.101280

Pickering, J. W., du Toit, S., Cheer, S., Buchan, V., Miller, R., Joyce, L. R., Than, M., & Florkowski, C. M. (2026). Analytical verification of a point-of-care high-sensitivity troponin I assay. Journal of Applied Laboratory Medicine, 11(2), 295-306. doi: 10.1093/jalm/jfaf181

Journal - Research Other

Pickering, J. W., Pilbrow, A. P., Fa'atoese, A., & Joyce, L. (2026). Addressing significant inequity. New Zealand Medical Journal/Te ara tika o te hauora hapori, 139(1631), 110-115. doi: 10.26635/6965.7313

Collinson, P., Lam, L., Pickering, J. W., Christenson, R., Van Hoovels, L., Jafri, L., … Than, M., … Aakre, K. M. (2026). Considerations and pragmatic strategies for implementation of point of care testing for high sensitivity cardiac troponin into the acute care setting. Clinical Chemistry & Laboratory Medicine. Advance online publication. doi: 10.1515/cclm-2026-0210

Meek, R., Lu, Z. X., Senarathne, U. D., Tan, S., Cullen, L., Pickering, J. W., Than, M. P., … Egerton-Warburton, D. (2026). Potential impact of a point-of-care high-sensitivity cardiac troponin assay on emergency department length of stay and patient disposition: Findings from a cardiac emergency department. Emergency Medicine Journal, 43(1), 30-32. doi: 10.1136/emermed-2025-214985

2025

Journal - Research Article

Keys, T., Greer, C., Adamson, P. D., Pickering, J. W., Pilbrow, A. P., Frampton, C., … Troughton, R. W., … Richards, A. M., Pemberton, C. J., & Chew-Harris, J. (2025). Soluble urokinase plasminogen activator receptor for risk stratification from undifferentiated acute chest pain through to convalescence after acute coronary syndromes. European Heart Journal Open, 5(5), oeaf097. doi: 10.1093/ehjopen/oeaf097

Pickering, J. W., Joyce, L., Devlin, G., Pemberton, C., Troughton, R., Richards, A. M., & Than, M. P. (2025). Improving Care with the First measurement of high-sensitivity troponin T (ICare-FirsT) to enable early rule out and reduce length of stay: A diagnostic and observational study. Emergency Medicine Journal, 42(9), 579-584. doi: 10.1136/emermed-2024-214754

Brokenshire, F., Pickering, J. W., Al-Busaidi, I. S., Than, M., Troughton, R., Addy, K., & Joyce, L. R. (2025). Atrial fibrillation patients presenting to an emergency department successfully managed with a next-day community follow-up pathway: A before-and-after cohort study. Emergency Medicine Australasia, 37, e70049. doi: 10.1111/1742-6723.70049

Joyce, L. R., Gutenstein, M., Gilbert, M., Weaver, J., Pearson, S., Pickering, J. W., & Than, M. (2025). Evaluation of a virtual emergency care service to avoid unnecessary emergency department presentations and provide specialist-led definitive care. Emergency Medicine Australasia, 37, e70048. doi: 10.1111/1742-6723.70048

Meek, R., Hayden, G., Lu, Z. X., Damianopoulos, A., Cullen, L., Kumarakurusingham, E., … Than, M., Pickering, J. W., … Egerton-Warburton, D. (2025). Potential length of stay reductions from emergency department use of a point-of-care high-sensitivity cardiac troponin assay: Pilot findings from Australia's first cardiac emergency department. Emergency Medicine Australasia, 37(2), e70041. doi: 10.1111/1742-6723.70041

Zangi, M., Pickering, J. W., Theadom, A., Than, M., & Snell, D. L. (2025). Mild and moderate traumatic brain injury: Screening, documentation, and referral to concussion services. Australasian Emergency Care, 28(3), 213-220. doi: 10.1016/j.auec.2025.03.007

Lee, J. A., Wise, J., Raudsepp, S. D., Paton, L. N., Powell, J., Jina, K., Aldous, S., Troughton, R. W., Adamson, P. D., Richards, A. M., … Than, M. P., Pickering, J. W., & Pemberton, C. J. (2025). Insulin-like growth factor binding protein-3 (IGFBP-3): A biomarker of coronary artery disease induced myocardial ischaemia. European Heart Journal Open, 5, oeaf028. doi: 10.1093/ehjopen/oeaf028

Pickering, J. W., Kelland, S., Williams, O., Kim, J., Aldous, S., Joyce, L. R., & Than, M. P. (2025). Effect of change of high-sensitivity troponin I assay on emergency department diagnosis and disposition of patients with possible acute coronary syndrome. Emergency Medicine Australasia, 37, e70022. doi: 10.1111/1742-6723.70022

Thießen, N., Pickering, J. W., Kellner, C., Haller, P. M., Lehmacher, J., Toprak, B., … Pemberton, C., Troughton, R., Richards, A. M., … Than, M., … Neumann, J. T. (2025). A common algorithm for cardiac troponin to rule out and rule in acute myocardial infarction. Canadian Journal of Cardiology, 41(7), 1351-1360. doi: 10.1016/j.cjca.2025.02.029

Restan, I. Z., Steiro, O.-T., Pickering, J. W., Tjora, H. L., Langørgen, J., Omland, T., … Aakre, K. M. (2025). Clinical derivation and data simulated validation of rule-out and rule-in algorithms for the Siemens Atellica IM high-sensitivity cardiac troponin I assay. European Heart Journal: Acute Cardiovascular Care, 14, 155-168. doi: 10.1093/ehjacc/zuaf017

Florkowski, C. M., Buchan, V., Li, B. V., Taylor, F., Phan, M., Than, M., & Pickering, J. W. (2025). Analytical verification of the Atellica VTLi point of care high sensitivity troponin I assay. Clinical Chemistry & Laboratory Medicine, 63(2), 433-439. doi: 10.1515/cclm-2024-0312

Journal - Research Other

Fann, L., Joyce, L. R., Pickering, J. W., Munro, A., Fisher, N., & Than, M. (2025). Point-of-care high-sensitivity troponin use in an ESC-type pathway for assessment of possible acute myocardial infarction in the emergency department. Emergency Medicine Australasia, 37, e70147. doi: 10.1111/1742-6723.70147

Brokenshire, F., Addy, K. R., Pickering, J. W., Al-Busaidi, I., Than, M., Troughton, R., & Joyce, L. R. (2025). Improving emergency department prescribing of anticoagulation for atrial fibrillation through an iterative quality improvement process. Emergency Medicine Australasia, 37(4), e70097. doi: 10.1111/1742-6723.70097

Kavsak, P. A., Thießen, N., Pickering, J. W., Liu, L., Sharif, S., Kirkwood, D., … Than, M., … Jaffe, A. S. (2025). Common change criteria for high-sensitivity cardiac troponin for serial measurements greater than 2 hours apart. CJC Open, 7(8), 1073-1074. doi: 10.1016/j.cjco.2025.05.010

Hickman, P. E., Potter, J. M., Cullen, L., Eggers, K. M., Than, M., Pickering, J. W., … Doust, J. (2025). Evidence-based medicine and the cardiac troponin 99th percentile for the diagnosis of acute myocardial infarction. European Heart Journal: Acute Cardiovascular Care, 14(3), 183-188. doi: 10.1093/ehjacc/zuaf007

Journal - Professional & Other Non-Research Articles

Pickering, J. W., Joyce, L. R., & Than, M. P. (2025). Response to: Clinical reflections on the impact of high-sensitivity troponin I assay changes on emergency department diagnosis and disposition. Emergency Medicine Australasia, 37, e70079. doi: 10.1111/1742-6723.70079

Conference Contribution - Verbal presentation and other Conference outputs

Pickering, J., & Joyce, L. (2025, September). Barriers and bridges to translating a new biomarker into clinical practice: The ICare-FASTER story. Verbal presentation at the Queenstown Research Week (QRW) Heart Satellite Meeting, Christchurch, New Zealand.

2024

Journal - Research Article

Pickering, J. W., Kavsak, P., Christenson, R. H., Troughton, R. W., Pemberton, C. J., Richards, A. M., Joyce, L., & Than, M. P. (2024). Determination of clinically acceptable analytical variation of cardiac troponin at decision thresholds. Clinical Chemistry, 70(7), 967-977. doi: 10.1093/clinchem/hvae059

Greer, C. E., Chew-Harris, J., Adamson, P. D., Pemberton, C. J., Pickering, J. W., Pilbrow, A. P., Frampton, C. M., Troughton, R. W., Doughty, R. N., & Richards, A. M. (2024). Convalescent growth differentiation factor-15 and long-term outcomes after an acute coronary syndrome. Journal of Applied Laboratory Medicine, 09(04), 672-683. doi: 10.1093/jalm/jfae032

Chew-Harris, J., Frampton, C., Greer, C., Appleby, S., Pickering, J. W., Kuan, W. S., … Adamson, P. D., Troughton, R., … Richards, A. M., & Pemberton, C. J. (2024). Prognostic performance of soluble urokinase plasminogen activator receptor for heart failure or mortality in Western and Asian patients with acute breathlessness. International Journal of Cardiology, 406, 132071. doi: 10.1016/j.ijcard.2024.132071

Pickering, J. W., Young, J. M., George, P. M., Watson, A. S., Aldous, S. J., Verryt, T., Troughton, R. W., Pemberton, C. J., Richards, A. M., … Than, M. P. (2024). Derivation and validation of thresholds using synthetic data methods for single-test screening of emergency department patients with possible acute myocardial infarction using a point-of-care troponin assay. Journal of Applied Laboratory Medicine, 9(3), 526-539. doi: 10.1093/jalm/jfae001

Emrich, I. E., Pickering, J. W., Götzinger, F., Kramann, R., Kunz, M., Lauder, L., … Mahfoud, F. (2024). Comparison of three creatinine-based equations to predict adverse outcome in a cardiovascular high-risk cohort: An investigation using the SPRINT research materials. Clinical Kidney Journal, 17(2), sfae011. doi: 10.1093/ckj/sfae011

Duncan, S., Bergler, H. U., Menclova, A., Pickering, J. W., Nishtala, P. S., Ailabouni, N., … Mangin, D., & Jamieson, H. (2024). The drug burden index and level of frailty as determinants of healthcare costs in a cohort of older frail adults in New Zealand [Economic evaluation]. Value in Health Regional Issues, 41, 72-79. doi: 10.1016/j.vhri.2023.11.009

Journal - Research Other

Pickering, J. W., Joyce, L. R., Florkowski, C. M., Buchan, V., Hamill, L., & Than, M. P. (2024). Emergency Department use of a high-sensitivity point-of-care troponin assay reduces length of stay: An implementation study preliminary report. European Heart Journal: Acute Cardiovascular Care, 13, 838-842. doi: 10.1093/ehjacc/zuae114

Than, M. P., Pickering, J. W., Mair, J., Mills, N. L., on behalf of the Study Group on Biomarkers of the Association for Acute CardioVascular Care of the ESC. (2024). Clinical decision support using machine learning and cardiac troponin for the diagnosis of myocardial infarction. European Heart Journal: Acute Cardiovascular Care, 13, 634-636. doi: 10.1093/ehjacc/zuae085

Pickering, J. W., Devlin, G., Body, R., Aldous, S., Jaffe, A. S., Apple, F. S., … Troughton, R. W., … Joyce, L., Frampton, C., Lacey, C. J., Richards, A. M., Pitama, S., & Than, M. (2024). Protocol for Improving Care by FAster risk-STratification through use of high sensitivity point-of-care troponin in patients presenting with possible acute coronary syndrome in the EmeRgency department (ICare-FASTER): A stepped-wedge cluster randomised quality improvement initiative. BMJ Open, 14, e083752. doi: 10.1136/bmjopen-2023-083752

Pickering, J. W., Hamill, L., Aldous, S., Joyce, L., Stothart, R. A., Williams, O., Florkowski, C. M., & Than, M. (2024). Determination of a whole-blood single-test low-risk threshold for a point-of-care high-sensitivity troponin assay. Emergency Medicine Journal, 41(5), 322-323. doi: 10.1136/emermed-2023-213689

Pickering, J. W. (2024). Troponin thresholds for myocardial infarction risk stratification. Academic Emergency Medicine, 31(3), 305. doi: 10.1111/acem.14865

Conference Contribution - Published proceedings: Abstract

Aldous, S., Pickering, J., Hamill, L., Joyce, L., & Than, M. (2024). The use of a point of care high sensitivity troponin in the investigation of patients presenting to the Emergency Department with undifferentiated chest pain. European Heart Journal, 45(Suppl. 1), ehae666.1581. doi: 10.1093/eurheartj/ehae666.1581

Pemberton, C. J., Lee, J. A., Wise, J., Raudsepp, S. D., Paton, L., Powell, J., … Troughton, R. W., Adamson, P. D., Richards, A. M., … Than, M., & Pickering, J. W. (2024). Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) measurement in the detection of significant CAD in acute chest pain patients triaged using the No Objective Testing (NOT) rule. European Heart Journal, 45(Suppl. 1), ehae666.1572. doi: 10.1093/eurheartj/ehae666.1572

Pilbrow, A., Fa'atoese, A., & Pickering, J. (2024). Making small studies count: The need for more appropriate data analysis and guidelines to avoid reinforcing inequities. Heart, Lung & Circulation, 33(Suppl. 2), (pp. S69). doi: 10.1016/j.hlc.2024.04.243

Pickering, J., Kavsak, P., Christenson, R., Troughton, R., Pemberton, C., Richards, M., Joyce, L., & Than, M. (2024). High-sensitivity troponin assays are safe to rule-out myocardial infarction even if they have high imprecision. Heart, Lung & Circulation, 33(Suppl. 2), (pp. S76). doi: 10.1016/j.hlc.2024.04.259

Joyce, L., Al-Busaidi, I., Pickering, J., Addy, K., Brokenshire, F., Troughton, R., & Than, M. (2024). The implementation and iteration of an emergency department atrial fibrillation pathway to improve patient care. Heart, Lung & Circulation, 33(Suppl. 2), (pp. S67-S68). doi: 10.1016/j.hlc.2024.04.240

Greer, G., Chew-Harris, J., Adamson, P., Pemberton, C., Pickering, J., Pilbrow, A., Troughton, R., Doughty, R., Richards, M., & Frampton, C. (2024). Convalescent GDF-15 and long-term outcomes after acute coronary syndrome. Heart, Lung & Circulation, 33(Suppl. 2), (pp. S74-S75). doi: 10.1016/j.hlc.2024.04.256

2023

Journal - Research Article

O'Conner Peluso, D., Esposito, T. M., Marchis, F., Dalba, P. A., Sgro, L., Megowan-Romanowicz, C., … Unistellar Citizen Scientists, including Pickering, J. W. (2023). The Unistellar Exoplanet campaign: Citizen science results and inherent education opportunities. Publications of the Astronomical Society of the Pacific, 135, 015001. doi: 10.1088/1538-3873/acaa58

Nishtala, P. S., Pickering, J. W., Bergler, U., Mangin, D., Hilmer, S. N., & Jamieson, H. (2023). Post hoc analyses of a randomized controlled trial for the effect of pharmacist deprescribing intervention on the anticholinergic burden in frail community-dwelling older adults. Journal of the American Medical Directors Association, 24(8), 1253-1260. doi: 10.1016/j.jamda.2023.05.014

Abey-Nesbit, R., Jamieson, H. A., Bergler, H. U., Kerse, N., Pickering, J. W., & Teh, R. (2023). Chronic health conditions and mortality among older adults with complex care needs in Aotearoa New Zealand. BMC Geriatrics, 23(1), 318. doi: 10.1186/s12877-023-03961-8

Doudesis, D., Lee, K. K., Boeddinghaus, J., Bularga, A., Ferry, A. V., Tuck, C., … Pickering, J. W., Than, M. P., … CoDE-ACS Investigators, including Richards, A. M., Pemberton, C., Troughton, R. W., & Aldous, S. J. (2023). Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations. Nature Medicine, 29, 1201-1210. doi: 10.1038/s41591-023-02325-4

Addy, K., Joyce, L. R., Al-Busaidi, I. S., Pickering, J. W., Troughton, R., & Than, M. (2023). Implementation of an integrated emergency department acute atrial fibrillation pathway safely reduces cardioversions and hospitalisations: A comparative pre-post study. Emergency Medicine Australasia, 35, 828-833. doi: 10.1111/1742-6723.14240

Neumann, J. T., Twerenbold, R., Ojeda, F., Aldous, S. J., Allen, B. R., Apple, F. S., … Pickering, J. W., Pemberton, C. J., … Richards, A. M., … Than, M. P., … Troughton, R. W., … the ARTEMIS study group. (2023). Personalized diagnosis in suspected myocardial infarction. Clinical Research in Cardiology, 112, 1288-1301. doi: 10.1007/s00392-023-02206-3

Koh, H. W. L., Pilbrow, A. P., Tan, S. H., Zhao, Q., Benke, P. I., Burla, B., … Pickering, J. W., Troughton, R., Pemberton, C., … Richards, A. M., & Chan, M. Y. (2023). An integrated signature of extracellular matrix proteins and a diastolic function imaging parameter predicts post-MI long-term outcomes. Frontiers in Cardiovascular Medicine, 10, 1123682. doi: 10.3389/fcvm.2023.1123682

Kavsak, P. A., Clark, L., Arnoldo, S., Lou, A., Shea, J. L., Eintracht, S., … Than, M., Pickering, J. W., … Jaffe, A. S. (2023). Analytic result variation for high-sensitivity cardiac troponin: Interpretation and consequences. Canadian Journal of Cardiology, 39(7), 947-951. doi: 10.1016/j.cjca.2023.04.013

Templeton, E. M., Pilbrow, A. P., Kleffmann, T., Pickering, J. W., Rademaker, M. T., Scott, N. J. A., Ellmers, L. J., Charles, C. J., Endre, Z. H., Richards, A. M., Cameron, V. A., & Lassé, M. (2023). Comparison of SPEED, S-Trap, and in-solution-based sample preparation methods for mass spectrometry in kidney tissue and plasma. International Journal of Molecular Sciences, 24(7), 6290. doi: 10.3390/ijms24076290

Graykowski, A., Lambert, R. A., Marchis, F., Cazeneuve, D., Dalba, P. A., Esposito, T. M., … Pickering, J. W., … Transom, I. M. (2023). Light curves and colors of the ejecta from dimorphos after the DART impact. Nature, 616, 461-464. doi: 10.1038/s41586-023-05852-9

Shaji, E. J., Al-Busaidi, I. S., Joyce, L. R., Pickering, J. W., Troughton, R. W., & Than, M. (2023). Factors predictive of spontaneous reversion to sinus rhythm: Findings from an integrated acute atrial fibrillation pathway. Heart Rhythm, 20(5), 779-780. doi: 10.1016/j.hrthm.2023.01.023

Jamieson, H., Nishtala, P. S., Bergler, H. U., Weaver, S. K., Pickering, J. W., Ailabouni, N. J., Abey-Nesbit, R., … Deely, J., … Mangin, D. (2023). Deprescribing anticholinergic and sedative drugs to reduce polypharmacy in frail older adults living in the community: A randomized controlled trial. Journals of Gerontology Series A, 78(9), 1692-1700. doi: 10.1093/gerona/glac249

Miller, R., Nixon, G., Stokes, T., Smith, M., Pickering, J. W., Liepins, T., … Than, M. (2023). The cost-savings of the rural accelerated chest pain pathway for low-risk chest pain in rural general practice: A cost minimisation analysis. Journal of Primary Health Care, 15(1), 71-76. doi: 10.1071/HC22117

Huang, X., Li, Y., Fowler, C., Doecke, J. D., Lim, Y. Y., Drysdale, C., … Pickering, J. W., … Gu, B. J. (2023). Leukocyte surface biomarkers implicate deficits of innate immunity in sporadic Alzheimer's disease. Alzheimer's & Dementia, 19(5), 2084-2094. doi: 10.1002/alz.12813

Journal - Research Other

Joyce, L. R., Pickering, J. W., & Than, M. (2023). Ruling out acute myocardial infarction based on a single high-sensitivity troponin measurement in the emergency department: A clinical practice review. Journal of Laboratory & Precision Medicine, 8, 21. doi: 10.21037/jlpm-23-20

Pickering, J. W., Joyce, L., & Than, M. (2023). Twenty-six years of machine learning for ECG: And we are not there yet. Canadian Journal of Emergency Medicine, 25, 789-790. doi: 10.1007/s43678-023-00598-9

Pickering, J. W. (2023). Machine learning for decision-making in cardiology: A narrative review to aid navigating the new landscape. Revista Española de Cardiología: English Edition, 76(8), 645-654. doi: 10.1016/j.rec.2023.02.009

Journal - Professional & Other Non-Research Articles

Lambert, R., Marchis, F., Hanuš, J., Archer, J., Billiani, M., Bradley, J. K., … Pickering, J. W., … Widi, J. (2023). Rotation period determination for (7335) 1989 JA. Minor Planet Bulletin, 50(1), 16-17. Retrieved from https://mpbulletin.org

Joyce, L. R., Addy, K. R., Al-Busaidi, I. S., Pickering, J. W., Troughton, R., & Than, M. (2023). Response to Re: Implementation of an integrated emergency department acute atrial fibrillation pathway safely reduces cardioversions and hospitalisations: A comparative pre-post study. Emergency Medicine Australasia, 35, 884. doi: 10.1111/1742-6723.14286

Conference Contribution - Published proceedings: Abstract

Dunn, E. T. K., Pickering, J., Joyce, L., & Than, M. (2023). ICare-SALLEE: Investigating care processes, through standardised allocation to emergent exercise stress training. Proceedings of the Graduate Research Student Symposium. (pp. 12). Retrieved from https://www.otago.ac.nz/graduate-research

Pickering, J. (2023). Faking it to making it: The use of synthetic data to derive biomarker diagnostic thresholds. Proceedings of the New Zealand Biostatistics Conference. Retrieved from https://events.otago.ac.nz/2023-biostatistics-conference

Jamieson, H., Scrase, R., Abey-Nesbit, R., Bergler, U., & Pickering, J. (2023). Development and validation of a frailty index comparable with three interRAI assessment instruments. Proceedings of the Australian and New Zealand Society for Geriatric Medicine (ANZSGM) Annual Scientific Medicine. Retrieved from https://www.anzsgmconference.org/

2022

Journal - Research Article

Eggers, K. M., Hammarsten, O., Aldous, S. J., Cullen, L., Greenslade, J., Lindahl, B., … Pemberton, C. J., Pickering, J. W., Richards, A. M., Troughton, R. W., & Than, M. P. (2022). Diagnostic and prognostic performance of the ratio between high-sensitivity cardiac troponin I and troponin T in patients with chest pain. PLoS ONE, 17(11), e0276645. doi: 10.1371/journal.pone.0276645

Pickering, J. W., Scrase, R., Troughton, R., & Jamieson, H. A. (2022). Evaluation of the added value of Brain Natriuretic Peptide to a validated mortality risk-prediction model in older people using a standardised international clinical assessment tool. PLoS ONE, 17(11), e0277850. doi: 10.1371/journal.pone.0277850

Abey-Nesbit, R., Bergler, U., Pickering, J. W., Nishtala, P. S., & Jamieson, H. (2022). Development and validation of a frailty index compatible with three interRAI assessment instruments. Age & Ageing, 51, afac178. doi: 10.1093/ageing/afac178

Norman, T., Young, J., Jones, J. S., Egan, G., Pickering, J., Du Toit, S., … Miller, R., Frampton, C., … George, P., & Than, M. (2022). Implementation and evaluation of a rural general practice assessment pathway for possible cardiac chest pain using point-of-care troponin testing: A pilot study. BMJ Open, 12, e044801. doi: 10.1136/bmjopen-2020-044801

Doudesis, D., Lee, K. K., Yang, J., Wereski, R., Shah, A. S. V., Tsanas, A., … Pickering, J. W., … on behalf of the High-STEACS Investigators. (2022). Validation of the myocardial-ischaemic-injury-index machine learning algorithm to guide the diagnosis of myocardial infarction in a heterogenous population: A prespecified exploratory analysis. Lancet Digital Health, 4, e300-e308. doi: 10.1016/s2589-7500(22)00025-5

Miller, R., Nixon, G., Pickering, J. W., Stokes, T., Turner, R. M., Young, J., Gutenstein, M., Smith, M., … Watson, A., George, P., … Than, M. (2022). A prospective multi-centre study assessing the safety and effectiveness following the implementation of an accelerated chest pain pathway using point-of-care troponin for use in New Zealand rural hospital and primary care settings. European Heart Journal: Acute Cardiovascular Care, 11(5), 418-427. doi: 10.1093/ehjacc/zuac037

Templeton, E. M., Lassé, M., Kleffmann, T., Ellmers, L. J., Palmer, S. C., Davidson, T., Scott, N. J. A., Pickering, J. W., Charles, C. J., Endre, Z. H., Cameron, V. A., Richards, A. M., Rademaker, M. T., & Pilbrow, A. P. (2022). Identifying candidate protein markers of acute kidney injury in acute decompensated heart failure. International Journal of Molecular Sciences, 23, 1009. doi: 10.3390/ijms23021009

Vincent, A., Pearson, S., Pickering, J. W., Weaver, J., Toney, L., Hamill, L., Hurrell, M., & Than, M. (2022). Sensitivity of modern multislice CT for subarachnoid haemorrhage at incremental timepoints after headache onset: A 10-year analysis. Emergency Medicine Journal, 39, 810-817. doi: 10.1136/emermed-2020-211068

Villacorta, H., Pickering, J. W., Horiuchi, Y., Olim, M., Coyne, C., Maisel, A. S., & Than, M. P. (2022). Machine learning with D-dimer in the risk stratification for pulmonary embolism: A derivation and internal validation study. European Heart Journal: Acute Cardiovascular Care, 11, 13-19. doi: 10.1093/ehjacc/zuab089

Journal - Research Other

Than, M., Richardson, S., & Pickering, J. (2022). Emergency department frequent attenders: Big data insights for a big and complex problem. Emergency Medicine Journal, 39(1), 2. doi: 10.1136/emermed-2021-211560

Conference Contribution - Published proceedings: Full paper

Carrington, A. M., Fieguth, P. W., Mayr, F., James, N. D., Holzinger, A., Pickering, J. W., & Aviv, R. I. (2022). The ROC diagonal is not layperson’s chance: A new baseline shows the useful area. In A. Holzinger, P. Kieseberg, A. M. Tjoa & E. Weippl (Eds.), Machine Learning and Knowledge Extraction: Proceedings of the International Cross-Domain Conference, CD-MAKE: Lecture Notes in Computer Science (Vol. 13480). (pp. 100-113). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-14463-9_7

Conference Contribution - Published proceedings: Abstract

Doudesis, D., Lee, K. K., Bularga, A., Ferry, A. V., Tuck, C., Anand, A., … Pickering, J. W., Than, M. P., … Mills, N. L. (2022). Machine learning to optimise use of cardiac troponin in the diagnosis of acute myocardial infarction. European Heart Journal, 43(Suppl. 2), (pp. 1349). doi: 10.1093/eurheartj/ehac544.1349

Templeton, E., Lassé, M., Cameron, V., Pickering, J., Kleffmann, T., Hertzberg, D., Frampton, C., Ellmers, L., Palmer, S., … Scott, N., Charles, C., … Richards, M., … Troughton, R., Rademaker, M., & Pilbrow, A. (2022). Harnessing the power of 'Omics': Discovering novel microRNA and protein biomarkers of acute kidney injury in acute heart failure. Heart, Lung & Circulation, 31(Suppl. 2), (pp. S23-S24). doi: 10.1016/j.hlc.2022.05.009

Conference Contribution - Poster Presentation (not in published proceedings)

Addy, K., Joyce, L., Al-Busaidi, I. S., Pickering, J. W., Troughton, R., & Than, M. (2022, November). Improvement in patient outcomes following implementation of an emergency department atrial fibrillation pathway using a 'rate-and-wait' approach. Poster session presented at the Australasian College for Emergency Medicine (ACEM) Spring Symposium, Christchurch, New Zealand.

2021

Journal - Research Article

Than, M. P., Pickering, J. W., Adamson, P., Clendon, T., Florkowski, C. M., Lainchbury, J., Loubser, J., … Aldous, S. J. (2021). Reducing patient risk and enhancing care through the development and implementation of a new chest pain pathway, expedited by and for the COVID-19 era. eJIFCC, 32(1), 27-40.

Chiang, C.-H., Chiang, C.-H., Pickering, J. W., Stoyanov, K. M., Chew, D. P., Neumann, J. T., … Than, M. P., & Lee, C.-C. (2021). Performance of the European society of Cardiology 0/1-hour, 0/2-hour, and 0/3-hour algorithms for rapid triage of acute myocardial infarction: An international collaborative meta-analysis. Annals of Internal Medicine. doi: 10.7326/m21-1499

Heidari, K., Arani, M. A., Sheibani, M., Pickering, J. W., & Chouhdari, A. (2021). Comparison of two diagnostic protocols in the management of possible cardiac chest pain: One follow-up study in Iran. Caspian Journal of Internal Medicine, 12(2), 148-154. doi: 10.22088/cjim.12.2.148

Abey-Nesbit, R., Peel, N. M., Matthews, H., Hubbard, R. E., Nishtala, P. S., Bergler, U., Deely, J. M., Pickering, J. W., Schluter, P. J., & Jamieson, H. A. (2021). Frailty of Māori, Pasifika, and non-Māori/non-Pasifika older people in New Zealand: A national population study of older people referred for home care services. Journals of Gerontology Series A, 76(6), 1101-1107. doi: 10.1093/gerona/glaa265

Templeton, E. M., Cameron, V. A., Pickering, J. W., Richards, A. M., & Pilbrow, A. P. (2021). Emerging microRNA biomarkers for acute kidney injury in acute decompensated heart failure. Heart Failure Reviews, 26, 1203-1217. doi: 10.1007/s10741-020-09928-w

Lamba, M., Pickering, J. W., Than, M., Iles, S., & Beckert, L. (2021). Long-term outcomes in patients with pulmonary embolism: Results from a longitudinal cohort study. Internal Medicine Journal, 51, 699-704. doi: 10.1111/imj.14409

Journal - Research Other

Bergler, U., Ailabouni, N. J., Pickering, J. W., Hilmer, S. N., Mangin, D., Nishtala, P. S., Jamieson, H., & Sponsor-investigator (2021). Deprescribing to reduce polypharmacy: Study protocol for a randomised controlled trial assessing deprescribing of anticholinergic and sedative drugs in a cohort of frail older people living in the community. Trials, 22, 766. doi: 10.1186/s13063-021-05711-w

Young, J. M., Sage, J. N., Pickering, J. W., Bannister, L., Aldous, S., George, P. M., & Than, M. P. (2021). Next-day troponin tests in real-world implementation of baseline troponin rule-out of myocardial infarction demonstrates minimal delayed troponin rises. Circulation, 143, 202-204. doi: 10.1161/circulationaha.120.047556

Sandoval, Y., Chapman, A. R., Mills, N. L., Than, M., Pickering, J. W., Worster, A., … Apple, F. S. (2021). Sex-specific kinetics of high-sensitivity cardiac troponin I and T following symptom onset and early presentation in non-ST-segment elevation myocardial infarction. Clinical Chemistry, 67(1), 321-324. doi: 10.1093/clinchem/hvaa263

Conference Contribution - Published proceedings: Abstract

Jamieson, H., Nishtala, P., Bergler, U., Ailabouni, N. J., Weaver, S., Pickering, J., Abey-Nesbit, R., … Gee, S., … Mangin, D. (2021). Deprescribing anticholinergic and sedative medications in older New Zealanders living in the community: A randomized controlled trial. Proceedings of the Australasian Pharmaceutical Science Association (APSA) Annual Conference. 217. Retrieved from https://www.apsa-online.org/

Templeton, E., Lassé, M., Kleffmann, T., Ellmers, L. J., Palmer, S. C., Davidson, T., Scott, N. J., Pickering, J. W., Charles, C. J., Endre, Z. H., Cameron, V. A., & Richards, A. M. (2021). Identifying candidate protein markers of acute kidney injury in acute decompensated heart failure. Heart, Lung & Circulation, 30(Suppl. 2), (pp. S66). doi: 10.1016/j.hlc.2021.05.020

2020

Journal - Research Article

Pickering, J. W., Abey-Nesbit, R., Allore, H., & Jamieson, H. (2020). Development and validation of multivariable mortality risk-prediction models in older people undergoing an interRAI home-care assessment (RiskOP). eClinicalMedicine, 29-30, 100614. doi: 10.1016/j.eclinm.2020.100614

Chan, M. Y., Efthymios, M., Tan, S. H., Pickering, J. W., Troughton, R., Pemberton, C., … Pilbrow, A., & Richards, A. M. (2020). Prioritizing candidates of post-myocardial infarction heart failure using plasma proteomics and single-cell transcriptomics. Circulation, 142, 1408-1421. doi: 10.1161/circulationaha.119.045158

Jamieson, H. A., Abey-Nesbit, R., & Pickering, J. W. (2020). Effect of capacity to undertake instrumental activities of daily living on entry to aged residential care in older people with heart failure. Frontiers in Medicine, 7, 386. doi: 10.3389/fmed.2020.00386

Albert, C., Zapf, A., Haase, M., Röver, C., Pickering, J. W., Albert, A., … Haase-Fielitz, A. (2020). Neutrophil gelatinase-associated lipocalin measured on clinical laboratory platforms for the prediction of acute kidney injury and the associated need for dialysis therapy: A systematic review and meta-analysis. American Journal of Kidney Diseases, 76(6), 826-841. doi: 10.1053/j.ajkd.2020.05.015

Jamieson, H., Abey-Nesbit, R., Nishtala, P. S., Allore, H., Han, L., Deely, J. M., & Pickering, J. W. (2020). Predictors of residential care admission in community-dwelling older people with dementia. Journal of the American Medical Directors Association, 21(11), 1665-1670. doi: 10.1016/j.jamda.2020.04.021

Hertzberg, D. P., Luksha, Y., Kus, I., Eslampia, P., Pickering, J. W., & Holzmann, M. J. (2020). Gait speed at discharge and risk for readmission or death: A prospective study of an emergency ward population. Open Access Emergency Medicine, 12, 127-135. doi: 10.2147/OAEM.S229479

Diefenhardt, P., Pickering, J. W., & Heine, G. H. (2020). Erlaubt eine Bestimmung von FGF23 bei chronisch nierenkranken Menschen eine verbesserte Vorhersage renaler und kardiovaskulärer Ereignisse? [Does a determination of FGF23 in chronic kidney disease allow improved prediction of renal and cardiovascular events?]. Nephrologe, 15, 112-113. doi: 10.1007/s11560-019-00399-1

Sanchis, J., Valero, E., Blas, S. G., Barba, E., Pernias, V., Miñana, G., … Pickering, J. W. (2020). Undetectable high-sensitivity troponin in combination with clinical assessment for risk stratification of patients with chest pain and normal troponin at hospital arrival. European Heart Journal: Acute Cardiovascular Care, 9(6), 567-575. doi: 10.1177/2048872620907539

Pickering, J. W., Young, J. M., George, P. M., Pemberton, C. J., Watson, A., Aldous, S. J., … Troughton, R. W., Richards, A. M., … Than, M. P. (2020). Early kinetic profiles of troponin I and T measured by high-sensitivity assays in patients with myocardial infarction. Clinica Chimica Acta, 505, 15-25. doi: 10.1016/j.cca.2020.02.009

Burnside, M., Crocket, H., Mayo, M., Pickering, J., Tappe, A., & de Bock, M. (2020). Do-it-yourself automated insulin delivery: A leading example of the democratization of medicine. Journal of Diabetes Science & Technology, 14(5), 878-882. doi: 10.1177/1932296819890623

Chiew, A. L., James, L. P., Isbister, G. K., Pickering, J. W., McArdle, K., Chan, B. S. H., & Buckley, N. A. (2020). Early acetaminophen-protein adducts predict hepatotoxicity following overdose (ATOM-5). Journal of Hepatology, 72, 450-462. doi: 10.1016/j.jhep.2019.10.030

Greenslade, J. H., Sieben, N., Parsonage, W. A., Knowlman, T., Ruane, L., Than, M., Pickering, J. W., … Cullen, L. (2020). Factors influencing physician risk estimates for acute cardiac events in emergency patients with suspected acute coronary syndrome. Emergency Medicine Journal, 37, 2-7. doi: 10.1136/emermed-2019-208916

Journal - Research Other

Miller, R., Young, J., Nixon, G., Pickering, J. W., Stokes, T., Turner, R., … Gutenstein, M., … George, P. M., … Than, M. (2020). Study protocol for an observational study to evaluate an accelerated chest pain pathway using point-of-care troponin in New Zealand rural and primary care populations. Journal of Primary Health Care, 12(2), 129-138. doi: 10.1071/HC19059

2019

Journal - Research Article

Than, M. P., Pickering, J. W., Sandoval, Y., Shah, A. S. V., Tsanas, A., Apple, F. S., … on behalf of the MI³ Collaborative. (2019). Machine learning to predict the likelihood of acute myocardial infarction. Circulation, 140, 899-909. doi: 10.1161/circulationaha.119.041980

Adamson, P. D., McAllister, D., Pilbrow, A., Pickering, J. W., Poppe, K., Shah, A., Whalley, G., … Pemberton, C., Troughton, R. W., … Richards, A. M. (2019). Convalescent troponin and cardiovascular death following acute coronary syndrome. Heart, 105, 1717-1724. doi: 10.1136/heartjnl-2019-315084

Neumann, J. T., Twerenbold, R., Ojeda, F., Sörensen, N. A., Chapman, A. R., Shah, A. S. V., … Pickering, J. W., Troughton, R. W., … Than, M., … Blankenberg, S. (2019). Application of high-sensitivity troponin in suspected myocardial infarction. New England Journal of Medicine, 380(26), 2529-2540. doi: 10.1056/NEJMoa1803377

Nestelberger, T., Cullen, L., Lindahl, B., Reichlin, T., Greenslade, J. H., Giannitsis, E., … Pickering, J. W., Than, M., on behalf of the APACE, ADAPT and TRAPID-AMI Investigators. (2019). Diagnosis of acute myocardial infarction in the presence of left bundle branch block. Heart, 105, 1559-1567. doi: 10.1136/heartjnl-2018-314673

Hertzberg, D. P., Sartipy, U., Lund, L. H., Rydén, L., Pickering, J. W., & Holzmann, M. J. (2019). Heart failure and the risk of acute kidney injury in relation to ejection fraction in patients undergoing coronary artery bypass grafting. International Journal of Cardiology, 274, 66-70. doi: 10.1016/j.ijcard.2018.09.092

Gutenstein, M., Pickering, J. W., & Than, M. (2019). Development of a digital clinical pathway for emergency medicine: Lessons from usability testing and implementation failure. Health Informatics Journal, 25(4), 1563-1571. doi: 10.1177/1460458218779099

Hertzberg, D., Holzmann, M. J., Than, M., & Pickering, J. W. (2019). Acute kidney injury in patients presenting with chest pain to the emergency department: A descriptive study of the most common discharge diagnoses and mortality. European Journal of Emergency Medicine, 26(4), 242-248. doi: 10.1097/mej.0000000000000552

Journal - Research Other

Pickering, J. W. (2019). The need to improve derivation and description of algorithms to rule-out patients with possible myocardial infarction. Circulation, 139(11), 1351-1353. doi: 10.1161/circulationaha.118.038418

Conference Contribution - Published proceedings: Abstract

Aldous, S., Pickering, J., Young, J., George, P., Watson, A., Troughton, R., Pemberton, C., Richards, M., … Than, M. (2019). Rapid rule-out of myocardial infarction with a novel high precision point-of-care troponin assay appears safe and effective. European Heart Journal, 40(Suppl. 1), (pp. 1626). doi: 10.1093/eurheartj/ehz748.0992

Sock Hwee, T., Koh, H. W. L., Chua, J. Y., Yang, X. X., Ong, C. C., Teo, L., … Pilbrow, A. P., Pickering, J. W., Troughton, R. W., … Richards, A. M., & Chan, M. Y. (2019). Plasma proteomics identify plaque-related proteins that predict long-term recurrent coronary events in patients with acute coronary syndrome. European Heart Journal, 40(Suppl. 1), (pp. 3588). doi: 10.1093/eurheartj/ehz746.0660

2018

Journal - Research Article

Farnaz, B., Payman, I., Mohammad, R., Pickering, J. W., & Seyed-Mostafa, H.-Z. (2018). Incidence of non-alcoholic fatty liver disease among referral outpatients to the internal medicine clinic. Asian Journal of Pharmaceutics, 12(Suppl. 1), S323-S327. doi: 10.22377/ajp.v12i01

Pickering, J. W., Young, J. M., George, P. M., Watson, A. S., Aldous, S. J., Troughton, R. W., Pemberton, C. J., Richards, A. M., … Than, M. P. (2018). Validity of a novel point-of-care troponin assay for single-test rule-out of acute myocardial infarction. JAMA Cardiology, 3(11), 1108-1112. doi: 10.1001/jamacardio.2018.3368

Kavsak, P. A., Neumann, J. T., Cullen, L., Than, M., Shortt, C., Greenslade, J. H., Pickering, J. W., … Troughton, R., … Worster, A. (2018). Clinical chemistry score versus high-sensitivity cardiac troponin I and T tests alone to identify patients at low or high risk for myocardial infarction or death at presentation to the emergency department. CMAJ, 190(33), E974-E984. doi: 10.1503/cmaj.180144

Than, M. P., Aldous, S. J., Troughton, R. W., Pemberton, C. J., Richards, A. M., Frampton, C. M. A., Florkowski, C. M., George, P. M., … Young, J. M., … Pickering, J. W. (2018). Detectable high-sensitivity cardiac troponin within the population reference interval conveys high 5-year cardiovascular risk: An observational study. Clinical Chemistry, 64(7), 1044-1053. doi: 10.1373/clinchem.2017.285700

van der Linden, N., Wildi, K., Twerenbold, R., Pickering, J. W., Than, M., Cullen, L., … Richards, A. M., Troughton, R., Pemberton, C., … Mueller, C. (2018). Combining high sensitivity cardiac troponin I and cardiac troponin T in the early diagnosis of acute myocardial infarction. Circulation, 138(10), 989-999. doi: 10.1161/circulationaha.117.032003

Seiler-Mussler, S., Limbach, A. S., Emrich, I. E., Pickering, J. W., Roth, H. J., Fliser, D., & Heine, G. H. (2018). Association of nonoxidized parathyroid hormone with cardiovascular and kidney disease outcomes in chronic kidney disease. Clinical Journal of the American Society of Nephrology, 13(4), 569-576. doi: 10.2215/cjn.06620617

McIlroy, D. R., Farkas, D., Pan, K., Pickering, J. W., & Lee, H. T. (2018). Combining novel renal injury markers with delta serum creatinine early after cardiac surgery and risk-stratification for serious adverse outcomes: An exploratory analysis. Journal of Cardiothoracic & Vascular Anesthesia, 32(5), 2190-2200. doi: 10.1053/j.jvca.2017.12.052

Greenslade, J. H., Chung, K., Parsonage, W. A., Hawkins, T., Than, M., Pickering, J. W., & Cullen, L. (2018). Modification of the Thrombolysis in Myocardial Infarction risk score for patients presenting with chest pain to the emergency department. Emergency Medicine Australasia, 30(1), 47-54. doi: 10.1111/1742-6723.12913

Pickering, J. W., Flaws, D., Smith, S. W., Greenslade, J., Cullen, L., Parsonage, W., … Richards, A. M., Troughton, R., Pemberton, C., George, P. M., & Than, M. P. (2018). A risk assessment score and initial high-sensitivity troponin combine to identify low risk of acute myocardial infarction in the emergency department. Academic Emergency Medicine, 25(4), 434-443. doi: 10.1111/acem.13343

Than, M. P., Pickering, J. W., Dryden, J. M., Lord, S. J., Aitken, S. A., Aldous, S. J., … Ardagh, M. W., … Callender, R., … Deely, J. M., … Ferrier, K. A., … Frampton, C. M. A., George, P. M., … Matthews, T. J. E., … Peckler, B. F., … Richards, A. M., … Simmonds, M. B., … Troughton, R. W., … on behalf of the ICare-ACS Implementation Group. (2018). ICare-ACS (improving care processes for patients with suspected acute coronary syndrome): A study of cross-system implementation of a national clinical pathway. Circulation, 137(4), 354-363. doi: 10.1161/circulationaha.117.031984

Carlton, E. W., Pickering, J. W., Greenslade, J., Cullen, L., Than, M., Kendall, J., … Greaves, K. (2018). Assessment of the 2016 National Institute for Health and Care Excellence high-sensitivity troponin rule-out strategy. Heart, 104(8), 665-672. doi: 10.1136/heartjnl-2017-311983

Pickering, J. W., Blunt, I. R. H., & Than, M. P. (2018). Acute kidney injury and mortality prognosis in acute coronary syndrome patients: A meta-analysis. Nephrology, 23(3), 237-246. doi: 10.1111/nep.12984

Journal - Research Other

Pickering, J. W., McCall, J. L., De Zoysa, J., & Soop, M. (2018). Response to the letter re: "Low versus standard urine output targets in patients undergoing major abdominal surgery". Annals of Surgery, 268(1), e23. doi: 10.1097/sla.0000000000002499

Conference Contribution - Published proceedings: Abstract

Lennartz, C. S., Seiler-Mußler, S., Emrich, I., Untersteller, K., Pickering, J., Fliser, D., & Heine, G. H. (2018). Sonographische Parameter als Prädiktoren der Progression der chronischen Nierenerkrankung: Langzeitdaten aus der CARE FOR HOMe Studie. Internist, 59(Suppl. 1), (pp. S14-S15). doi: 10.1007/s00108-018-0419-y

Aldous, S., Pickering, J., Cullen, L., Richards, M., & Than, M. (2018). The investigation and treatment of women who present with acute chest pain, varies little compared with men when stratified by risk. Heart, Lung & Circulation, 27(Suppl. 1), (pp. S8). doi: 10.1016/j.hlc.2018.05.118

Lamba, M., Pickering, J., Than, M., Iles, S., & Beckert, L. (2018). Diagnosis of pulmonary embolism does not increase long-term risk of adverse clinical events. Respirology, 23(Suppl. 1), (pp. 189). doi: 10.1111/resp.13268

2017

Journal - Research Article

Wildi, K., Cullen, L., Twerenbold, R., Greenslade, J. H., Parsonage, W., Boeddinghaus, J., … Pickering, J. W., Than, M., & Mueller, C. (2017). Direct comparison of 2 rule-out strategies for acute myocardial infarction: 2-h accelerated diagnostic protocol vs 2-h algorithm. Clinical Chemistry, 63(7), 1227-1236. doi: 10.1373/clinchem.2016.268359

The New Zealand Emergency Medicine Network, including Gutenstein, M., and the Shorter Stays in Emergency Department National Research Project Group, including Pickering, J. (2017). National audit of the quality of pain relief provided in emergency departments in Aotearoa, New Zealand: The PRiZED 1 Study. Emergency Medicine Australasia, 29(2), 165-172. doi: 10.1111/1742-6723.12714

Neumann, J. T., Sörensen, N. A., Ojeda, F., Schwemer, T., Lehmacher, J., Gönner, S., … Pickering, J. W., … Blankenberg, S. (2017). Immediate rule-out of acute myocardial infarction using electrocardiogram and baseline high-sensitivity troponin I. Clinical Chemistry, 63(1), 394-402. doi: 10.1373/clinchem.2016.262659

Chapman, A. R., Lee, K. K., McAllister, D. A., Cullen, L., Greenslade, J. H., Parsonage, W., … Pickering, J. W., Than, M. P., … Adamson, P., … Mills, N. L. (2017). Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome. JAMA, 318(19), 1913-1924. doi: 10.1001/jama.2017.17488

Succar, L., Pianta, T. J., Davidson, T., Pickering, J. W., & Endre, Z. H. (2017). Subclinical chronic kidney disease modifies the diagnosis of experimental acute kidney injury. Kidney International, 92(3), 680-692. doi: 10.1016/j.kint.2017.02.030

Pickering, J. W., Than, M. P., Cullen, L., Aldous, S., ter Avest, E., Body, R., … Florkowski, C. M., … George, P., … Pemberton, C., Richards, A. M., … Troughton, R., … Young, J. (2017). Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac troponin T measurement below the limit of detection: A collaborative meta-analysis. Annals of Internal Medicine, 166(10), 715-724. doi: 10.7326/m16-2562

Mohamed, F., Buckley, N. A., Pickering, J. W., Wunnapuk, K., Dissanayake, S., Chathuranga, U., … Endre, Z. H. (2017). Nephrotoxicity-induced proteinuria increases biomarker diagnostic thresholds in acute kidney injury. BMC Nephrology, 18(1), 122. doi: 10.1186/s12882-017-0532-7

Pianta, T. J., Pickering, J. W., Succar, L., Chin, M., Davidson, T., Buckley, N. A., … Endre, Z. H. (2017). Dexamethasone modifies cystatin C-based diagnosis of acute kidney injury during cisplatin-based chemotherapy. Kidney & Blood Pressure Research, 62-75. doi: 10.1159/000469715

Greenslade, J. H., Nayer, R., Parsonage, W., Doig, S., Young, J., Pickering, J. W., Than, M., … Cullen, L. (2017). Validating the Manchester Acute Coronary Syndromes (MACS) and Troponin-only Manchester Acute Coronary Syndromes (T-MACS) rules for the prediction of acute myocardial infarction in patients presenting to the emergency department with chest pain. Emergency Medicine Journal, 34(8), 517-523. doi: 10.1136/emermed-2016-206366

Ribitsch, W., Schilcher, G., Quehenberger, F., Pilz, S., Portugaller, R. H., Truschnig-Wilders, M., … Pickering, J. W., & Horina, J. H. (2017). Neutrophil gelatinase-associated lipocalin (NGAL) fails as an early predictor of contrast induced nephropathy in chronic kidney disease (ANTI-CI-AKI study). Scientific Reports, 7, 41300. doi: 10.1038/srep41300

Puckett, J. R., Pickering, J. W., Palmer, S. C., McCall, J. L., Kluger, M. T., De Zoysa, J., Endre, Z. H., & Soop, M. (2017). Low versus standard urine output targets in patients undergoing major abdominal surgery: A randomized noninferiority trial. Annals of Surgery, 265(5), 874-881. doi: 10.1097/sla.0000000000002044

Journal - Research Other

Hertzberg, D., Rydén, L., Pickering, J. W., Sartipy, U., & Holzmann, M. J. (2017). Acute kidney injury: An overview of diagnostic methods and clinical management. Clinical Kidney Journal, 10(3), 323-331. doi: 10.1093/ckj/sfx003

Than, M. P., Pickering, J. W., Cullen, L., & Kavsak, P. A. (2017). Response by Than et al to letter regarding article, "Assessment of the European Society of Cardiology 0-Hour/1-Hour algorithm to rule-out and rule-in acute myocardial infarction". Circulation, 135(16), e923-e924. doi: 10.1161/circulationaha.117.027479

Pickering, J. W., & Than, M. P. (2017). The small number problem in diagnostic algorithms and why we need to bootstrap. Clinical Biochemistry, 50(9), 540-541. doi: 10.1016/j.clinbiochem.2017.02.009

Conference Contribution - Published proceedings: Abstract

Scott-Jones, J., Norman, T., Than, M., Devlin, G., Egan, G., George, P., Young, J., Pickering, J., … Hamilton, F. (2017). Measured implementation of an accelerated chest pain diagnostic pathway in primary care. Heart, Lung & Circulation, 26(Suppl. 1), (pp. S41). doi: 10.1016/j.hlc.2017.05.110

Aldous, S., Pickering, J., Richards, M., Troughton, R., Cullen, L., & Than, M. (2017). Comparison of five accelerated diagnostic protocols for stratification of patients presenting with acute chest pain. Heart, Lung & Circulation, 26(Suppl. 1). doi: 10.1016/j.hlc.2017.05.038

2016

Journal - Research Article

Pickering, J. W., Greenslade, J. H., Cullen, L., Flaws, D., Parsonage, W., Aldous, S., George, P., … Than, M. P. (2016). Assessment of the European Society of Cardiology 0-Hour/1-Hour algorithm to rule-out and rule-in acute myocardial infarction. Circulation, 134(20), 1532-1541. doi: 10.1161/circulationaha.116.022677

Wang, M. H., Chong, K. C., Storer, M., Pickering, J. W., Endre, Z. H., Lau, S. Y. F., … Zee, B. C. Y. (2016). Use of a least absolute shrinkage and selection operator (LASSO) model to selected ion flow tube mass spectrometry (SIFT-MS) analysis of exhaled breath to predict the efficacy of dialysis: A pilot study. Journal of Breath Research, 10(4), 046004. doi: 10.1088/1752-7155/10/4/046004

Bauer, L., Emrich, I. E., Pickering, J. W., Untersteller, K., Sandermann, F., Rogacev, K. S., … Heine, G. H. (2016). Best albuminuria measurement to predict cardiovascular and renal events. American Journal of Nephrology, 43, 383-388. doi: 10.1159/000446483

Cullen, L., Greenslade, J. H., Carlton, E. W., Than, M., Pickering, J. W., Ho, A., … Parsonage, W. A. (2016). Sex-specific versus overall cut points for a high sensitivity troponin I assay in predicting 1-year outcomes in emergency patients presenting with chest pain. Heart, 102, 102-126. doi: 10.1136/heartjnl-2015-308506

Parsonage, W. A., Mueller, C., Greenslade, J. H., Wildi, K., Pickering, J., Than, M., … Cullen, L. (2016). Validation of NICE diagnostic guidance for rule out of myocardial infarction using high-sensitivity troponin tests. Heart, 102, 1279-1286. doi: 10.1136/heartjnl-2016-309270

Flaws, D., Than, M., Scheuermeyer, F. X., Christenson, J., Boychuk, B., Greenslade, J. H., … Deely, J. M., Pickering, J. W., & Cullen, L. (2016). External validation of the emergency department assessment of chest pain score accelerated diagnostic pathway (EDACS-ADP). Emergency Medicine Journal, 33, 618-625. doi: 10.1136/emermed-2015-205028

Young, J. M., Pickering, J. W., George, P. M., Aldous, S. J., Wallace, J., Frampton, C. M., Troughton, R. W., Richards, A. M., … Than, M. P. (2016). Heart Fatty Acid Binding Protein and cardiac troponin: Development of an optimal rule-out strategy for acute myocardial infarction. BMC Emergency Medicine, 16(1), 34. doi: 10.1186/s12873-016-0089-y

Pickering, J. W., & Endre, Z. H. (2016). Bench to bedside: The next steps for biomarkers in acute kidney injury. American Journal of Physiology: Renal Physiology, 311(4), F717-F721. doi: 10.1152/ajprenal.00268.2016

Carlton, E., Greenslade, J., Cullen, L., Body, R., Than, M., Pickering, J. W., Aldous, S., … Greaves, K. (2016). Evaluation of high-sensitivity cardiac troponin I levels in patients with suspected acute coronary syndrome. JAMA Cardiology, 1(4), 405-412. doi: 10.1001/jamacardio.2016.1309

Mohamed, F., Endre, Z. H., Pickering, J. W., Jayamanne, S., Palangasinghe, C., Shahmy, S., … Buckley, N. A. (2016). Mechanism-specific injury biomarkers predict nephrotoxicity early following glyphosate surfactant herbicide (GPSH) poisoning. Toxicology Letters, 258, 1-10. doi: 10.1016/j.toxlet.2016.06.001

Trambas, C., Pickering, J. W., Than, M., Bain, C., Nie, L., Paul, E., … Schneider, H. G. (2016). Impact of high-sensitivity troponin I testing with sex-specific cutoffs on the diagnosis of acute myocardial infarction. Clinical Chemistry, 62(6), 831-838. doi: 10.1373/clinchem.2015.252569

Endre, Z. H., Pianta, T. J., & Pickering, J. W. (2016). Timely diagnosis of acute kidney injury using kinetic eGFR and the creatinine excretion to production ratio, E/eG: Creatinine can be useful! Nephron Clinical Practice, 132, 312-316. doi: 10.1159/000444456

Md Ralib, A., Mat Nor, M. B., & Pickering, J. W. (2016). Plasma Neutrophil Gelatinase-Associated Lipocalin diagnosed acute kidney injury in patients with systemic inflammatory disease and sepsis. Nephrology, 22(5), 412-419. doi: 10.1111/nep.12796

Than, M. P., Pickering, J. W., Aldous, S. J., Cullen, L., Frampton, C. M. A., Peacock, W. F., … Richards, A. M., Ardagh, M. W., Deely, J. M., Florkowski, C. M., George, P., Hamilton, G. J., Jardine, D. L., Troughton, R. W., … Lord, S. J. (2016). Effectiveness of EDACS versus ADAPT accelerated diagnostic pathways for chest pain: A pragmatic randomized controlled trial embedded within practice. Annals of Emergency Medicine, 68(1), 93-102. doi: 10.1016/j.annemergmed.2016.01.001

Pickering, J. W., Greenslade, J. H., Cullen, L., Flaws, D., Parsonage, W., George, P., … Than, M. P. (2016). Validation of presentation and 3 h high-sensitivity troponin to rule-in and rule-out acute myocardial infarction. Heart, 102, 1270-1278. doi: 10.1136/heartjnl-2015-308505

Boeddinghaus, J., Reichlin, T., Cullen, L., Greenslade, J. H., Parsonage, W. A., Hammett, C., Pickering, J. W., … Aldous, S., … Than, M., & Mueller, C. (2016). Two-hour algorithm for triage towards rule-out and rule-in of acute myocardial infarction by use of high-sensitivity cardiac troponin I. Clinical Chemistry, 62(3), 494-504. doi: 10.1373/clinchem.2015.249508

Lennartz, C. S., Pickering, J. W., Seiler-Mußler, S., Bauer, L., Untersteller, K., Emrich, I. E., … Heine, G. H. (2016). External validation of the kidney failure risk equation and re-calibration with addition of ultrasound parameters. Clinical Journal of the American Society of Nephrology, 11(4), 609-615. doi: 10.2215/cjn.08110715

Cullen, L., Greenslade, J. H., Menzies, L., Leong, A., Than, M., Pemberton, C., Aldous, S., Pickering, J., … Parsonage, W. A. (2016). Time to presentation and 12-month health outcomes in patients presenting to the emergency department with symptoms of possible acute coronary syndrome. Emergency Medicine Journal, 33, 390-395. doi: 10.1136/emermed-2015-204978

Mat-Nor, M. B., Ralib, A. M., Abdulah, N. Z., & Pickering, J. W. (2016). The diagnostic ability of procalcitonin and Interleukin-6 to differentiate infectious from non-infectious systemic inflammatory response syndrome and to predict mortality. Journal of Critical Care, 33, 245-251. doi: 10.1016/j.jcrc.2016.01.002

Greenslade, J. H., Parsonage, W., Than, M., Scott, A., Aldous, S., Pickering, J. W., … Cullen, L. (2016). A clinical decision rule to identify emergency department patients at low risk for acute coronary syndrome who do not need objective coronary artery disease testing: The no objective testing rule. Annals of Emergency Medicine, 67(4), 478-489. doi: 10.1016/j.annemergmed.2015.08.006

Sanders, S., Flaws, D., Than, M., Pickering, J. W., Doust, J., & Glasziou, P. (2016). Simplification of a scoring system maintained overall accuracy but decreased the proportion classified as low risk. Journal of Clinical Epidemiology, 69, 32-39. doi: 10.1016/j.jclinepi.2015.05.006

2015

Journal - Research Article

Aldous, S., Richards, A. M., Cullen, L., Pickering, J. W., & Than, M. (2015). The incremental value of stress testing in patients with acute chest pain beyond serial cardiac troponin testing. Emergency Medicine Journal, 33(5), 319-324. doi: 10.1136/emermed-2015-204823

Pickering, J. W., Young, J. M., George, P., Aldous, S., Cullen, L., Greenslade, J. H., Richards, A. M., Troughton, R., Ardagh, M., Frampton, C. M., & Than, M. P. (2015). The utility of presentation and 4-hour high sensitivity troponin I to rule-out acute myocardial infarction in the emergency department. Clinical Biochemistry, 48(18), 1219-1224. doi: 10.1016/j.clinbiochem.2015.07.033

Pianta, T. J., Peake, P. W., Pickering, J. W., Kelleher, M., Buckley, N. A., & Endre, Z. H. (2015). Evaluation of biomarkers of cell cycle arrest and inflammation in prediction of dialysis or recovery after kidney transplantation. Transplant International, 28(12), 1392-1404. doi: 10.1111/tri.12636

Takaki, S., Shehabi, Y., Pickering, J. W., Endre, Z., Miyashita, T., & Goto, T. (2015). Perioperative change in creatinine following cardiac surgery with cardiopulmonary bypass is useful in predicting acute kidney injury: A single-centre retrospective cohort study. Interactive Cardiovascular & Thoracic Surgery, 21(4), 465-469. doi: 10.1093/icvts/ivv184

Mohamed, F., Buckley, N. A., Jayamanne, S., Pickering, J. W., Peake, P., Palangasinghe, C., … Endre, Z. H. (2015). Kidney damage biomarkers detect acute kidney injury but only functional markers predict mortality after paraquat ingestion. Toxicology Letters, 237(2), 140-150. doi: 10.1016/j.toxlet.2015.06.008

Greenslade, J. H., Kavsak, P., Parsonage, W. A., Shortt, C., Than, M., Pickering, J. W., Aldous, S., & Cullen, L. (2015). Combining presentation high-sensitivity cardiac troponin I and glucose measurements to rule-out an acute myocardial infarction in patients presenting to emergency department with chest pain. Clinical Biochemistry, 48(4-5), 288-291. doi: 10.1016/j.clinbiochem.2014.11.019

Pianta, T. J., Endre, Z. H., Pickering, J. W., Buckley, N. A., & Peake, P. W. (2015). Kinetic estimation of GFR improves prediction of dialysis and recovery after kidney transplantation. PLoS ONE, 10(5), e0125669. doi: 10.1371/journal.pone.0125669

Eggers, K. M., Aldous, S., Greenslade, J. H., Johnston, N., Lindahl, B., Parsonage, W. A., Pickering, J. W., Than, M., & Cullen, L. (2015). Two-hour diagnostic algorithms for early assessment of patients with acute chest pain: Implications of lowering the cardiac troponin I cut-off to the 97.5th percentile. Clinica Chimica Acta, 445, 19-24. doi: 10.1016/j.cca.2015.03.002

Emrich, I., Pickering, J. W., Schöttker, B., Lennartz, C. S., Rogacev, K. S., Holleczek, B., … Heine, G. H. (2015). Comparison of the performance of 2 GFR estimating equations using creatinine and cystatin C to predict adverse outcomes in elderly individuals. American Journal of Kidney Diseases, 65(4), 636-638. doi: 10.1053/j.ajkd.2014.12.006

Pickering, J. W., James, M. T., & Palmer, S. C. (2015). Acute kidney injury and prognosis after cardiopulmonary bypass: A meta-analysis of cohort studies. American Journal of Kidney Diseases, 65(2), 283-293. doi: 10.1053/j.ajkd.2014.09.008

Pianta, T. J., Peake, P. W., Pickering, J. W., Kelleher, M., Buckley, N. A., & Endre, Z. H. (2015). Clusterin in kidney transplantation: Novel biomarkers versus serum creatinine for early prediction of delayed graft function. Transplantation, 99(1), 171-179. doi: 10.1097/tp.0000000000000256

Journal - Research Other

Chew-Harris, J. S. C., Pickering, J. W., George, P. M., Endre, Z. H., & Florkowski, C. M. (2015). Beware the dog that didn't bark: A tale of creatinine in acute kidney injury. Internal Medicine Journal, 45(8), 878-879. doi: 10.1111/imj.12826

Conference Contribution - Published proceedings: Abstract

Pemberton, C. J., Lee, J., Than, M., Pickering, J. W., Troughton, R. W., & Richards, M. (2015). Can copeptin assist the diagnosis of acute kidney injury in breathless patients? European Heart Journal, 36(Suppl. 1), (pp. 800). doi: 10.1093/eurheartj/ehv400

Pickering, J. W., Young, J. M., George, P., Wallace, J., Aldous, S., Troughton, R., Richards, A. M., & Martin, M. P. (2015). An updated heart fatty acid binding protein assay facilitates improved rule-out of acute myocardial infarction within 2 hours of entry to the emergency department: Threshold derivation and validation. European Heart Journal, 36(Suppl. 1), (pp. 591). doi: 10.1093/eurheartj/ehv400

Pickering, J. W., Young, J. M., George, P., Aldous, S., Troughton, R., Richards, A. M., … Than, M. (2015). The 99th percentile of an updated heart Fatty Acid Binding Protein assay combines with high sensitive Troponin l to rule out acute myocardial infarction on presentation to the emergency department. European Heart Journal, 36(Suppl. 1), (pp. 4). doi: 10.1093/eurheartj/ehv398

Borrie, T. L., Young, M. L., Vella-Brincat, J. W. A., Doogue, M. P., & Pickering, J. W. (2015). Medication errors in patients undergoing elective surgery. Proceedings of the Australasian Pharmaceutical Science Association and the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (APSA-ASCEPT) Joint Scientific Meeting: Drugs to Medicines: Up Close and Personal. 511. Retrieved from http://www.asceptasm.com/

Menzies, L., Cullen, L., Greenslade, J., Leong, A., Than, M., Pemberton, C., Aldous, S., Pickering, J., … Parsonage, W. (2015). The association of delay in presentation and 12-month health outcomes in emergency patients with symptoms of possible acute coronary syndromes. Heart, Lung & Circulation, 24(Suppl. 3), (pp. S167-S168). doi: 10.1016/j.hlc.2015.06.134

Emrich, I. E., Bauer, L., Pickering, J. W., Untersteller, K., Seiler, S., Fliser, D., & Heine, G. H. (2015). Prognostic value of the "Estimated Albumin Excretion Rate" to predict renal events in chronic kidney disease. Nephrology Dialysis Transplantation, 30(Suppl. 3), (pp. 497-498). doi: 10.1093/ndt/gfv192

Bauer, L., Emrich, I. E., Pickering, J. W., Untersteller, K., Sandermann, F., Rogacev, K. S., … Heine, G. H. (2015). The prognostic value of "Estimated Albumin Excretion Rate" (EAER) versus urine Albumin/Creatinine Ratio (ACR) for predicting adverse cardiovascular outcome among patients with chronic kidney disease G2-G4. Nephrology Dialysis Transplantation, 30(Suppl. 3), (pp. 150-151). doi: 10.1093/ndt/gfv173

2014

Journal - Research Article

Ralib, A. M., Pickering, J. W., Shaw, G. M., Than, M. P., George, P. M., & Endre, Z. H. (2014). The clinical utility window for acute kidney injury biomarkers in the critically ill. Critical Care, 18, 601. doi: 10.1186/s13054-014-0601-2

Pickering, J. W., & Mellas, J. (2014). A simple method to detect recovery of glomerular filtration rate following acute kidney injury. BioMed Research International, 2014, 542069. doi: 10.1155/2014/542069

Pickering, J. W., & Endre, Z. H. (2014). Acute kidney injury urinary biomarker time-courses. PLoS ONE, 9(7), e101288. doi: 10.1371/journal.pone.0101288

Rogacev, K. S., Pickering, J. W., Seiler, S., Zawada, A. M., Emrich, I., Fliser, D., & Heine, G. H. (2014). The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation incorporating both cystatin C and creatinine best predicts individual risk: A cohort study in 444 patients with chronic kidney disease. Nephrology Dialysis Transplantation, 29(2), 348-355. doi: 10.1093/ndt/gft422

Journal - Research Other

Endre, Z. H., & Pickering, J. W. (2014). Acute kidney injury: Cell cycle arrest biomarkers win race for AKI diagnosis [News & Views]. Nature Reviews Nephrology, 10, 683-685. doi: 10.1038/nrneph.2014.198

Endre, Z. H., & Pickering, J. W. (2014). Acute kidney injury: Late-onset acute kidney injury—subacute or more of the same? [News & Views]. Nature Reviews Nephrology, 10, 133-134. doi: 10.1038/nrneph.2014.9

Pickering, J. W., & Endre, Z. H. (2014). The definition and detection of acute kidney injury. Journal of Renal Injury Prevention, 3(1), 21-25. doi: 10.12861/jrip.2014.08

Conference Contribution - Published proceedings: Abstract

Pianta, T. J., Peake, P., Pickering, J. W., Buckley, N., & Endre, Z. H. (2014). Urinary biomarkers of cell cycle arrest and inflammation for prediction of dialysis or recovery after kidney transplantation. Journal of the American Society of Nephrology, 25, (pp. 792A). [Abstract]

Pianta, T. J., Endre, Z. H., Pickering, J. W., Buckley, N., & Peake, P. (2014). Kinetic estimation of GFR improves prediction of dialysis or recovery after kidney transplantation. Journal of the American Society of Nephrology, 25, (pp. 370A). [Abstract]

Mohamed, F., Buckley, N., Pickering, J. W., Peake, P., & Endre, Z. H. (2014). Urinary cystatin C, clusterin and NGAL are early predictors of acute kidney injury (AKI) aafter paraquat poisoning. Journal of the American Society of Nephrology, 25, (pp. 134A). [Abstract]

Mohamed, F., Buckley, N., Pickering, J. W., Wunnapuk, K., Peake, P., & Endre, Z. H. (2014). Paraquat induced proteinuria amplifies renal biomarker excretion and increases biomarker diagnostic thresholds. Journal of the American Society of Nephrology, 25, (pp. 134A). [Abstract]

Conference Contribution - Poster Presentation (not in published proceedings)

Lennartz, C. S., Seiler, S., Rogacev, K. S., Untersteller, K., Emrich, I., Fliser, D., Pickering, J., & Heine, G. H. (2014, September). Vergleich sonographischer Parameter zur Beurteilung der Progression der chronischen Nierenerkrankung: RRI vs DI-RISK. Poster session presented at the 6th Jahrestagung der Deutschen Gesellschaft für Nephrologie [6th Annual Meeting of the German Society of Nephrology], Berlin, Germany.

Emrich, I., Pickering, J., Schöttker, B., Brenner, H., Rothenbacher, D., Holleczek, B., … Heine, G. H. (2014, May-June). BIS-2 EGFR is not better than CKD-EPI creat-CYS EGFR to predict adverse outcomes among elderly people in the ESTHER Study. Poster session presented at the 51st European Renal Association and the European Dialysis and Transplant Association (ERA-EDTA) Congress, Amsterdam, The Netherlands.

2013

Journal - Research Article

Md Ralib, A., Pickering, J. W., Shaw, G. M., & Endre, Z. H. (2013). The urine output definition of acute kidney injury is too liberal. Critical Care, 17, R112. doi: 10.1186/cc12784

Pickering, J. W., & Endre, Z. H. (2013). The clinical utility of plasma neutrophil gelatinase-associated lipocalin in acute kidney injury. Blood Purification, 35(4), 295-302. doi: 10.1159/000351542

Pickering, J. W., Ralib, A. M., & Endre, Z. H. (2013). Combining creatinine and volume kinetics identifies missed cases of acute kidney injury following cardiac arrest. Critical Care, 17, R7. doi: 10.1186/cc11931

Pickering, J. W., & Endre, Z. H. (2013). Linking injury to outcome in acute kidney injury: A matter of sensitivity. PLoS ONE, 8(4), e62691. doi: 10.1371/journal.pone.0062691

Ralib, A. M., Pickering, J. W., Major, T., Palmer, S. C., Shaw, G. M., Goodkin, D. A., & Endre, Z. H. (2013). High-dose intravenous epoetin does not increase blood pressure in critically ill patients with acute kidney injury. Clinical Nephrology, 79(5), 370-379. doi: 10.5414/cn107673

Endre, Z. H., & Pickering, J. W. (2013). Acute kidney injury clinical trial design: Old problems, new strategies. Pediatric Nephrology, 28(2), 207-217. doi: 10.1007/s00467-012-2171-3

Journal - Research Other

Endre, Z. H., & Pickering, J. W. (2013). Biomarkers and creatinine in AKI: The trough of disillusionment or the slope of enlightenment? Kidney International, 84(4), 644-647. doi: 10.1038/ki.2013.168

Pickering, J. (2013). Fascinating study which may have more stories to tell [Comment]. Critical Care, 17(3), R108.

Pickering, J. W., & Endre, Z. H. (2013). Not everything is relative [eLetter reply to Comparison of absolute serum creatinine changes versus Kidney Disease: Improving Global Outcomes consensus definitions for characterizing stages of acute kidney injury]. Nephrology Dialysis Transplantation. doi: 10.1093/ndt/gfs533

Conference Contribution - Published proceedings: Abstract

Pickering, J. W., & Endre, Z. H. (2013). Modelling acute kidney injury (AKI) biomarkers. Journal of the American Society of Nephrology, 24, (pp. 881A). [Abstract]

Pianta, T. J., Peake, P., Buckley, N., Pickering, J. W., Kelleher, M., & Endre, Z. H. (2013). Urinary clusterin predicts poor recovery of renal function within four hours of transplantation. Journal of the American Society of Nephrology, 24, (pp. 851A). [Abstract]

Pianta, T. J., Peake, P., Buckley, N., Pickering, J. W., Chin, M., & Endre, Z. H. (2013). Plasma cystatin C should not be used to diagnose AKI after cisplatin therapy. Journal of the American Society of Nephrology, 24, (pp. 373A). [Abstract]

Pianta, T., Peake, P., Buckley, N., Kelleher, M., Pickering, J., & Endre, Z. (2013). Urinary clusterin predicts graft recovery within four hours of kidney transplantation. Nephrology, 18(Suppl. 1), (pp. 43). doi: 10.1111/nep.12121

Pianta, T., Chin, M., Peake, P., Buckley, N., Pickering, J., & Endre, Z. (2013). Plasma cystatin C is elevated in the absence of acute kidney injury following cisplatin with contemporary antiemetics. Nephrology, 18(Suppl. 1), (pp. 41). doi: 10.1111/nep.12121

Md Ralib, A., Pickering, J. W., Shaw, G. M., & Endre, Z. H. (2013). Urine output criteria in prediction of mortality or dialysis requirements in the critically ill. Proceedings of the World Congress of Nephrology. Retrieved from http://www.theisn.org/

Md Ralib, A., Pickering, J. W., Shaw, G. M., Than, M., & Endre, Z. H. (2013). Earlier measurement of biomarkers does not enhance detection of acute kidney injury following significant kidney hypoperfusion. Proceedings of the World Congress of Nephrology. Retrieved from http://www.theisn.org/

Md Ralib, A., Pickering, J. W., Shaw, G. M., Than, M., & Endre, Z. H. (2013). The impact of fluid overload on mortality and acute kidney injury. Proceedings of the World Congress of Nephrology. Retrieved from http://www.theisn.org/

Takaki, S., Yahya, S., Philip, P., Pickering, J., & Endre, Z. (2013). Creatinine reduction ratio (CCR) is useful for excluding AKI after cardiac surgery: A preliminary retrospective study. European Journal of Anaesthesiology, 30(Suppl. 51), (pp. 192). [Abstract]

Seiler, S., Rogacev, K. S., Pickering, J. W., Emrich, I., Fliser, D., & Heine, G. (2013). The creatinine and cystatin C based CKD-EPI equation improves risk prediction of renal outcome in CKD patients. Nephrology Dialysis Transplantation, 28(Suppl. 1), (pp. 136). [Abstract]

2012

Chapter in Book - Research

Pickering, J. W., & Endre, Z. H. (2012). The metamorphosis of acute renal failure to acute kidney injury. In M. Sahay (Ed.), Basic nephrology and acute kidney injury. (pp. 125-150). Rijeka, Croatia: InTech. doi: 10.5772/1298

Journal - Research Article

Pickering, J. W., & Endre, Z. H. (2012). Challenges facing early detection of acute kidney injury in the critically ill. World Journal of Critical Care Medicine, 1(3), 61-66. doi: 10.5492/wjccm.v1.i3.61

Pickering, J. W., Frampton, C. M., Walker, R. J., Shaw, G. M., & Endre, Z. H. (2012). Four hour creatinine clearance is better than plasma creatinine for monitoring renal function in critically ill patients. Critical Care, 16, R107. doi: 10.1186/cc11391

Nejat, M., Pickering, J. W., Devarajan, P., Bonventre, J. V., Edelstein, C. L., Walker, R. J., & Endre, Z. H. (2012). Some biomarkers of acute kidney injury are increased in pre-renal acute injury. Kidney International, 81, 1254-1262. doi: 10.1038/ki.2012.23

Pickering, J. W., & Endre, Z. H. (2012). New metrics for assessing diagnostic potential of candidate biomarkers. Clinical Journal of the American Society of Nephrology, 7(8), 1355-1364. doi: 10.2215/cjn.09590911

Md Ralib, A., Pickering, J. W., Shaw, G. M., Devarajan, P., Edelstein, C. L., Bonventre, J. V., & Endre, Z. H. (2012). Test characteristics of urinary biomarkers depend on quantitation method in acute kidney injury. Journal of the American Society of Nephrology, 23(2), 322-333. doi: 10.1681/asn.2011040325

Nejat, M., Hill, J. V., Pickering, J. W., Edelstein, C. L., Devarajan, P., & Endre, Z. H. (2012). Albuminuria increases cystatin C excretion: Implications for urinary biomarkers. Nephrology Dialysis Transplantation, 27(Suppl. 3), iii96-iii103. doi: 10.1093/ndt/gfr222

Conference Contribution - Published proceedings: Abstract

Pickering, J. W., & Endre, Z. H. (2012). Determination of biomarker cut-offs in acute kidney injury. Journal of the American Society of Nephrology, 23, (pp. 123A). [Abstract]

Pickering, J. W., & Endre, Z. H. (2012). Acute kidney injury diagnosis delayed by intravenous fluids. Journal of the American Society of Nephrology, 23, (pp. 647A). [Abstract]

Md Ralib, A., Pickering, J. W., Shaw, G., Than, M., & Endre, Z. H. (2012). Transient Acute Kidney Injury (AKI) is common following significant renal hypoperfusion. Nephrology, 17(Suppl. 2), (pp. 54). doi: 10.1111/j.1440-1797.2012.01632.x

Pickering, J. W., Frampton, C. M., Walker, R. J., Shaw, G. M., & Endre, Z. H. (2012). 4-hour creatinine clearance in the intensive care unit. Nephrology, 17(Suppl. 2), (pp. 45). doi: 10.1111/j.1440-1797.2012.01631.x

Pickering, J. W., & Endre, Z. H. (2012). It is a risky business: New metrics for assessing candidate biomarkers. Nephrology, 17(Suppl. 2), (pp. 76). doi: 10.1111/j.1440-1797.2012.01633.x

Conference Contribution - Poster Presentation (not in published proceedings)

Md Ralib, A., Pickering, J., Shaw, G., Than, M., & Endre, Z. (2012, September). Transient acute kidney injury is common following significant renal hypoperfusion. Poster session presented at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Pickering, J. W. (2012, May). Utilizing urinary biomarkers in Acute Kidney Injury trial design. Verbal presentation at the Target Meeting's Clinical Trial Online Symposium, [Online].

2011

Journal - Research Article

Pickering, J. W., Md Ralib, A., Nejat, M., & Endre, Z. (2011). New considerations in the design of clinical trials of acute kidney injury. Clinical Investigation, 1(5), 637-650. doi: 10.4155/CLI.11.38

Endre, Z. H., Pickering, J. W., & Walker, R. J. (2011). Clearance and beyond: The complementary roles of GFR measurement and injury biomarkers in acute kidney injury (AKI). American Journal of Physiology: Renal Physiology, 301(4), F697-F707. doi: 10.1152/ajprenal.00448.2010

Endre, Z. H., & Pickering, J. W. (2011). New markers of acute kidney injury: Giant leaps and baby steps. Clinical Biochemist Reviews, 32(2), 121-124.

Endre, Z. H., Pickering, J. W., Walker, R. J., Devarajan, P., Edelstein, C. L., Bonventre, J. V., Frampton, C. M., … Shaw, G. M., Henderson, S. J., Nejat, M., Schollum, J. B. W., & George, P. M. (2011). Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney International, 79, 1119-1130. doi: 10.1038/ki.2010.555

Journal - Research Other

Md Ralib, A., Pickering, J. W., & Endre, Z. H. (2011). Predictor of early diagnosis, diagnosis, or progression of acute kidney injury [Letter to the editor]. Annals of Emergency Medicine, 57(1), 75-76. doi: 10.1016/j.annemergmed.2010.06.598

Pickering, J. W., Md Ralib, A., & Endre, Z. H. (2011). Was it the nephrologists or the fluid? [Letter to the editor]. American Journal of Kidney Diseases, 58(1), 154. doi: 10.1053/j.ajkd.2011.04.012

Pickering, J. W., & Endre, Z. H. (2011). Baseline creatinine: Where to from here? [Letter to the editor]. Nephrology Dialysis Transplantation, 26(6), 2056-2066. doi: 10.1093/ndt/gfr099

Journal - Professional & Other Non-Research Articles

Pickering, J. W. (2011). Survivor bias in early- vs late-start hemodialysis studies [Letter]. Archives of Internal Medicine, 171(5), 477. doi: 10.1001/archinternmed.2011.55

Conference Contribution - Published proceedings: Abstract

Nejat, M., Pickering, J. W., Devarajan, P., Bonventre, J. V., Edelstein, C. L., & Endre, Z. H. (2011). Acute kidney injury (AKI) biomarkers are increased in prerenal AKI. Proceedings of the World Congress of Nephrology 2011. International Society of Nephrology (ISN). Retrieved from http://www.theisn.org/

Ralib, A., Pickering, J. W., Devarajan, P., & Endre, Z. H. (2011). The utility of biomarker excretion rates in acute kidney injury (AKI). Proceedings of the World Congress of Nephrology 2011. International Society of Nephrology (ISN). Retrieved from http://www.theisn.org/

Pickering, J. W. (2011). Early intervention in acute kidney injury: The promise and the challengers. Proceedings of the 6th Congress of Nephrology in Internet (CIN). Retrieved from http://cin2011.uninet.edu/en/trabajos/212.html

Endre, Z. H., Md Ralib, A., Pickering, J. W., Major, T., Goodkin, D. A., & Palmer, S. (2011). Acute high-dose intravenous epoetin does not increase blood pressure in critically ill patients with acute kidney injury. Journal of the American Society of Nephrology, 22(Abstract Suppl.), (pp. 296A). [Abstract]

2010

Journal - Research Article

Endre, Z. H., Pickering, J. W., Storer, M. K., Hu, W.-P., Moorhead, K. T., Allardyce, R., McGregor, D. O., & Scotter, J. M. (2010). Breath ammonia and trimethylamine allow real-time monitoring of haemodialysis efficacy. Physiological Measurement, 32(1), 115-130. doi: 10.1088/0967-3334/32/1/008

Nejat, M., Pickering, J. W., Walker, R. J., Westhuyzen, J., Shaw, G. M., Frampton, C. M., & Endre, Z. H. (2010). Urinary cystatin C is diagnostic of acute kidney injury and sepsis, and predicts mortality in the intensive care unit. Critical Care, 14(3), R85. doi: 10.1186/cc9014

Pickering, J. W., & Endre, Z. H. (2010). Back-calculating baseline creatinine with MDRD misclassifies acute kidney injury in the intensive care unit. Clinical Journal of the American Society of Nephrology, 5, 1165-1173. doi: 10.2215/CJN.08531109

Nejat, M., Pickering, J. W., Walker, R. J., & Endre, Z. H. (2010). Rapid detection of acute kidney injury by plasma cystatin C in the intensive care unit. Nephrology Dialysis Transplantation, 25, 3283-3289. doi: 10.1093/ndt/gfq176

Endre, Z. H., Walker, R. J., Pickering, J. W., Shaw, G. M., Frampton, C. M., Henderson, S. J., Hutchison, R., … Robinson, J. M., Schollum, J. B. W., … Celi, L. A., … George, P. M. (2010). Early intervention with erythropoietin does not affect the outcome of acute kidney injury (the EARLYARF trial). Kidney International, 77, 1020-1030. doi: 10.1038/ki.2010.25

Ting, Y. T., Coates, T. P., Marti, H. P., Dunn, A. C., Parker, R. M., Pickering, J. W., Jack, R. W., Kemp, R. A., Walker, R. J., & McLellan, A. D. (2010). Urinary soluble HLA-DR is a potential biomarker for acute renal transplant rejection. Transplantation, 89(9), 1071-1078. doi: 10.1097/TP.0b013e3181d15492

Endre, Z. H., & Pickering, J. W. (2010). Outcome definitions in non-dialysis intervention and prevention trials in acute kidney injury (AKI). Nephrology Dialysis Transplantation, 25(1), 107-118. doi: 10.1093/ndt/gfp501

Conference Contribution - Published proceedings: Abstract

Nejat, M., Hill, J. V., Pickering, J. W., & Endre, Z. H. (2010). Experimentally induced overload albuminuria increases urinary cystatin C excretion. Journal of the American Society of Nephrology, 21, (pp. 348A). [Abstract]

Endre, Z. H., Pickering, J. W., Walker, R. J., Devarajan, P., Edelstein, C. L., & Bonventre, J. V. (2010). Duration of injury and baseline renal function define biomarker performance in acute kidney injury. Journal of the American Society of Nephrology, 21, (pp. 3A). [Abstract]

Nejat, M., Hill, J. V., Pickering, J. W., & Endre, Z. H. (2010). Does albumin overload albuminuria increase urinary cystatin C excretion? New Zealand Medical Journal, 123(1319). Retrieved from http://journal.nzma.org.nz/journal/123-1319/4254/content.pdf

Pickering, J. W., & Endre, Z. H. (2010). New and better biomarkers of acute kidney injury. Pathology, 42(Suppl. 1), (pp. S21). doi: 10.3109/00313021003600606

Conference Contribution - Poster Presentation (not in published proceedings)

Nejat, M., Pickering, J., & Endre, Z. (2010, September). Urinary cystatin C is diagnostic of sepsis and Acute Kidney Injury (AKI) and plasma cystatin C increases before plasma creatinine in intensive care unit patients. Poster session presented at the Fourth Annual Division of Health Sciences Research Forum, Dunedin, New Zealand.

2009

Journal - Research Article

Pickering, J. W., Frampton, C. M., & Endre, Z. H. (2009). Evaluation of trial outcomes in acute kidney injury by creatinine modeling. Clinical Journal of the American Society of Nephrology, 4(11), 1705-1715. doi: 10.2215/cjn.00820209

Pickering, J. W., & Endre, Z. H. (2009). Secondary prevention of acute kidney injury. Current Opinion in Critical Care, 15(6), 488-497. doi: 10.1097/MCC.0b013e328332f66f

Journal - Research Other

Pickering, J. W., & Endre, Z. H. (2009). GFR shot by RIFLE: Errors in staging acute kidney injury. Lancet, 373(9672), 1318-1319. doi: 10.1016/S0140-6736(09)60751-0

Journal - Professional & Other Non-Research Articles

Pickering, J. W., & Endre, Z. H. (2009). RIFLE and AKIN - maintain the momentum and the GFR! [Letter]. Critical Care, 13. doi: 10.1186/cc8019

Conference Contribution - Published proceedings: Abstract

Nejat, M., Pickering, J. W., & Endre, Z. H. (2009). Urinary Cystatin C as a prognostic biomarker for mortality in intensive care units (ICU) patients. Proceedings of the World Congress of Nephrology. Retrieved from http://www.abstracts2view.com/wcn/view.php?nu=WCN09L_306

Pickering, J. W., & Endre, Z. H. (2009). Baseline creatinines should not be determined by back-calculation in trials or epidemiological studies of AKI. Journal of the American Society of Nephrology. 20, (pp. 115A-116A). [Abstract]

Nejat, M., Pickering, J. W., & Endre, Z. H. (2009). Urinary cystatin C is a biomarker of sepsis and acute kidney injury (AKI) in the intensive care. Journal of the American Society of Nephrology. 20, (pp. 357A-358A). [Abstract]

Nejat, M., Pickering, J. W., & Endre, Z. H. (2009). Plasma cystatin C increases before plasma creatinine in intensive care unit patients. Journal of the American Society of Nephrology. 20, (pp. 357A). [Abstract]

2008

Chapter in Book - Research

Pickering, J. W. (2008). Plagiarism. In V. N. Parrillo (Ed.), Encyclopedia of social problems (Vol. 2). (pp. 664-667). Thousand Oaks, CA: SAGE.

Chapter in Book - Other

Leong, F. T. L., Zhang, H., Pickering, J., & Chang, J. (2008). Family and home country influences on adjustment (Case Incident 7: Responses). In N. Arthur & P. Pedersen (Eds.), Case incidents in counseling for international transitions. (pp. 99-112). Alexandria, VA: American Counseling Association.

2007

Chapter in Book - Research

McGrath, T., Butcher, A., Koo, Y., Pickering, J., & Smith, H. (2007). Engaging Asian communities in Aotearoa New Zealand: An exploration of what works in community research. In A. Williamson & R. DeSouza (Eds.), Researching with communities: Grounded perspectives on engaging communities in research. (pp. 385-398). Auckland, New Zealand: Muddy Creek Press.