Overview
Head of Department of Pathology and Biomedical Science
Director, Carney Centre for Pharmacogenomics
Laboratory Director, Gene Structure and Function Laboratory
Email martin.kennedy@otago.ac.nzTel +64 3 364 0590
Research interests
Professor Martin Kennedy's main research interests are psychiatric genetics, pharmacogenomics, and the genetics of complex disease.
His current research largely focuses on pharmacogenomics, which aims to understand how drugs and genes interact with the goal of improving drug treatments and reducing adverse drug reactions. For example, analysis of genetic variation in genes such as those that encode drug metabolising liver enzymes like CYP2D6 and CYP2C19, is helping to determine genetic factors that impact on response to treatments for various diseases.
For a more comprehensive analysis of genetic factors impacting drug response or risks of adverse drug reactions, they are also applying Next Generation DNA sequencing methods including exome sequencing and other genomic approaches to explore drug response phenotypes.
In order to understand severe adverse drug reactions, his lab has developed a biobank for collecting biological samples of people who have suffered such reactions, called UDRUGS. This biobank is growing, and will enhance efforts to understand genetic factors that contribute to severe adverse drug reactions.
Other research interests include work with the Christchurch Health and Development Study looking at genetic contributions to a range of complex human traits, and a study focusing on the genetics of anorexia nervosa.
In addition, Martin's laboratory is examining the impact of G-quadruplex DNA structures and their relevance to genomic imprinting and other aspects of genome biology.
Education
Professor Kennedy obtained his BSc(Hons) at University of Canterbury, and his PhD in bacterial genetics at the University of Auckland, and carried out postdoctoral research in leukaemia genetics at the Laboratory of Molecular Biology, Cambridge (UK) before returning to University of Otago, Christchurch in 1991.
In the media
Professor Martin Kennedy was interviewed for Radio New Zealand's Our Changing World series in May 2013.
Useful information
Similar research opportunities
- Analysis of the pharmacogene CYP2D6 using nanopore DNA sequencing system
- Genetic and genomic analysis of diseases and their treatments
- Genome sequencing and human susceptibility to Legionella longbeachae infection
- Genomics of disease and drug responses
- Genomics of disease and drug responses
Affiliations
Orcid Identifier
Publications
Publications
Turner, A. J., Nofziger, C., Ramey, B. E., Ly, R. C., Bousman, C. A., Agúndez, J. A. G., … Kennedy, M. A., … Gaedigk, A. (2023). PharmVar tutorial on CYP2D6 structural variation testing and recommendations on reporting [Tutorial]. Clinical Pharmacology & Therapeutics. Advance online publication. doi: 10.1002/cpt.3044 Journal - Research Other
Kee, P. S., Karunanathie, H., Maggo, S. D. S., Kennedy, M. A., & Chua, E. W. (2023). Long-range polymerase chain reaction. In L. Domingues (Ed.), PCR: Methods and protocols: Methods in molecular biology (Vol. 2967). (2nd ed.) (pp. 181-192). New York, NY: Humana. doi: 10.1007/978-1-0716-3358-8_15 Chapter in Book - Research
Morillon, M. B., Nørup, A., Singh, J. A., Dalbeth, N., Taylor, W. J., Kennedy, M. A., … Grainger, R., … Stamp, L. K. (2023). Outcome reporting in randomized trials in Gout: A systematic scoping review from the OMERACT Gout Working Group assessing the uptake of the core outcome set. Seminars in Arthritis & Rheumatism. Advance online publication. doi: 10.1016/j.semarthrit.2023.152191 Journal - Research Article
Kee, P. S., Maggo, S. D. S., Kennedy, M. A., & Chin, P. K. L. (2023). The pharmacogenetics of CYP2D6 and CYP2C19 in a case series of antidepressant responses [Brief research report]. Frontiers in Pharmacology, 14, 1080117. doi: 10.3389/fphar.2023.1080117 Journal - Research Article
Cleland, L., Kennedy, H. L., Pettie, M. A., Kennedy, M. A., Bulik, C. M., & Jordan, J. (2023). Eating disorders, disordered eating, and body image research in New Zealand: A scoping review. Journal of Eating Disorders, 11(1), 7. doi: 10.1186/s40337-022-00728-1 Journal - Research Article
Prickett, T. C. R., Pearson, J. F., Troughton, R. W., Kennedy, M. A., & Espiner, E. A. (2023). The predictive value of A, B, and C-type natriuretic peptides in people at risk of heart disease: Protocol for a longitudinal observational study. JMIR Research Protocols, 12, e37011. doi: 10.2196/37011 Journal - Research Other
Johnson, J. S., Cote, A. C., Dobbyn, A., Sloofman, L. G., Xu, J., Cotter, L., … Eating Disorders Working Group of the Psychiatric Genomics Consortium, including Boden, J. M., Pearson, J. F., … Jordan, J., Kennedy, M., … Huckins, L. M. (2023). Mapping anorexia nervosa genes to clinical phenotypes. Psychological Medicine, 53, 2619-2633. doi: 10.1017/s0033291721004554 Journal - Research Article
Kee, P. S., Maggo, S. D. S., Kennedy, M. A., Barclay, M. L., Miller, A. L., Lehnert, K., … Chin, P. K. L. (2022). Omeprazole treatment failure in gastroesophageal reflux disease and genetic variation at the CYP2C locus [Brief research report]. Frontiers in Genetics, 13, 869160. doi: 10.3389/fgene.2022.869160 Journal - Research Other
Hitchman, L. M., Faatoese, A., Merriman, T. R., Miller, A. L., Liau, Y., Graham, O. E. E., Kee, P. S., Pearson, J. F., … Cameron, V. A., Kennedy, M. A., & Maggo, S. D. S. (2022). Allelic diversity of the pharmacogene CYP2D6 in New Zealand Māori and Pacific peoples. Frontiers in Genetics, 13, 1016416. doi: 10.3389/fgene.2022.1016416 Journal - Research Article
Sidari, M., Mitchell, B., Conde, L. C., Maguire, S., Kennedy, M., Jordan, J., … Martin, N. (2022). Using multi-polygenic risk score analyses to predict anorexia nervosa case status. European Neuropsychopharmacology, 63, (pp. e125). doi: 10.1016/j.euroneuro.2022.07.233 Conference Contribution - Published proceedings: Abstract
Hitchman, L. M., Faatoese, A., Merriman, T. R., Miller, A. L., Liau, Y., Graham, O. E. E., Kee, P. S., Pearson, J. F., … Cameron, V. A., Kennedy, M. A., & Maggo, S. D. S. (2022, August-September). Allelic diversity of the pharmacogene CYP2D6 in New Zealand Māori and Pacific peoples. Poster session presented at the 31st Queenstown Molecular Biology Meeting (QMB), Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Liau, Y., Maggo, S., Lehnert, K., Doogue, M. P., Scull, A., Miller, A. L., Pearson, J. F., & Kennedy, M. A. (2022, August-September). Genomic analysis of angiotensin converting enzyme inhibitor-induced angioedema. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) NZ Annual Scientific Meeting, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Kee, P. S., Maggo, S., Kennedy, M. A., Barclay, M. L., Miller, A., Lehnert, K., … Faull, R. L. M., … Chin, P. K. L. (2022, August-September). Omeprazole treatment failure in gastro-oesophageal reflux disease and genetic variation at the CYP2C locus. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) NZ Annual Scientific Meeting, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
MacDermod, C., Pettie, M. A., Carrino, E. A., Cruz Garcia, S., Padalecki, S., Finch, J. E., … Kennedy, H. L., … Kennedy, M. A., Cleland, L., Jordan, J., … Bulik, C. M. (2022). Recommendations to encourage participation of individuals from diverse backgrounds in psychiatric genetic studies. American Journal of Medical Genetics Part B, 189B, 163-173. doi: 10.1002/ajmg.b.32906 Journal - Research Other
Xu, J., Johnson, J. S., Signer, R., Eating Disorders Working Group of the Psychiatric Genomics Consortium, Birgegård, A., Jordan, J., Kennedy, M. A., … Bulik, C. M., & Huckins, L. M. (2022). Exploring the clinical and genetic associations of adult weight trajectories using electronic health records in a racially diverse biobank: A phenome-wide and polygenic risk study. Lancet Digital Health, 4, e604-e614. doi: 10.1016/S2589-7500(22)00099-1 Journal - Research Article
Noble, A. J., Pearson, J. F., Noble, A. D., Boden, J. M., Horwood, L. J., Kennedy, M. A., & Osborne, A. J. (2022). DNA methylation analysis using bisulphite-based amplicon sequencing of individuals exposed to maternal tobacco use during pregnancy, and offspring conduct problems in childhood and adolescence. Reproduction, Fertility & Development, 34(7), 540-548. doi: 10.1071/rd21108 Journal - Research Article
Kennedy, H. L., Dinkler, L., Kennedy, M. A., Bulik, C. M., & Jordan, J. (2022). How genetic analysis may contribute to the understanding of avoidant/restrictive food intake disorder (ARFID). Journal of Eating Disorders, 10, 53. doi: 10.1186/s40337-022-00578-x Journal - Research Other
Surgenor, L. J., Dhakal, S., Watterson, R., Lim, B., Kennedy, M., Bulik, C., … Jordan, J. (2022). Psychosocial and financial impacts for carers of those with eating disorders in New Zealand. Journal of Eating Disorders, 10, 37. doi: 10.1186/s40337-022-00565-2 Journal - Research Article
Stevens, A. J., de Jong, L., & Kennedy, M. A. (2022). The dynamic regulation of G-quadruplex DNA structures by cytosine methylation. International Journal of Molecular Sciences, 23, 2407. doi: 10.3390/ijms23052407 Journal - Research Other
Karunanathie, H., Kee, P. S., Ng, S. F., Kennedy, M. A., & Chua, E. W. (2022). PCR enhancers: Types, mechanisms, and applications in long-range PCR. Biochimie, 197, 130-143. doi: 10.1016/j.biochi.2022.02.009 Journal - Research Article
Watson, H. J., Thornton, L. M., Yilmaz, Z., Baker, J. H., Coleman, J. R. I., Adan, R. A. H., … Boden, J. M., … Horwood, L. J., … Jordan, J., Kennedy, M., … Bulik, C. M. (2022). Common genetic variation and age at onset of anorexia nervosa. Biological Psychiatry: Global Open Science, 2, 368-378. doi: 10.1016/j.bpsgos.2021.09.001 Journal - Research Article
Kennedy, M. (2021, October). EDGing towards understanding the genetics of eating disorders. UOC Research Seminar Series, University of Otago, Christchurch, New Zealand. [Research Presentation]. Other Research Output
Noble, A. J., Pearson, J. F., Kennedy, M. A., Boden, J. M., Horwood, L. J., & Osborne, A. J. (2021). Does DNA methylation link the association between maternal tobacco use during pregnancy and altered offspring neurodevelopment. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 292). Retrieved from https://www.faobmb2021.org Conference Contribution - Published proceedings: Abstract
Maggo, S., Kee, J., Hitchman, L., Chin, P., Doogue, M., Miller, A., … Kennedy, M. (2021). Assessing the pharmacogenomic landscape of adverse drug reactions in Aotearoa [Invited]. Proceedings of the Genetics Otago (GO) Annual Symposium. Retrieved from https://blogs.otago.ac.nz/go Conference Contribution - Published proceedings: Abstract
Morillon, M. B., Christensen, R., Singh, J. A., Dalbeth, N., Saag, K., Taylor, W. J., … Kennedy, M. A., … Grainger, R., … Stamp, L. K., for the OMERACT Gout Working Group. (2021). Serum urate as a proposed surrogate outcome measure in gout trials: From the OMERACT Working Group. Seminars in Arthritis & Rheumatism, 51, 1378-1385. doi: 10.1016/j.semarthrit.2021.11.004 Journal - Research Article
Ip, H. F., van der Laan, C. M., Krapohl, E. M. L., Brikell, I., Sánchez-Mora, C., Nolte, I. M., … Miller, A., … Boden, J., Pearson, J., Horwood, L. J., Kennedy, M., Poulton, R., … Boomsma, D. I. (2021). Genetic association study of childhood aggression across raters, instruments, and age. Translational Psychiatry, 11, 413. doi: 10.1038/s41398-021-01480-x Journal - Research Article
Bulik, C. M., Thornton, L. M., Parker, R., Kennedy, H., Baker, J. H., MacDermod, C., … Cleland, L., Miller, A. L., … Jordan, J., Kennedy, M. A., & Martin, N. G. (2021). The Eating Disorders Genetics Initiative (EDGI): Study protocol. BMC Psychiatry, 21(1), 234. doi: 10.1186/s12888-021-03212-3 Journal - Research Other
Seddon, A. R., Liau, Y., Pace, P. E., Miller, A. L., Das, A. B., Kennedy, M. A., Hampton, M. B., & Stevens, A. J. (2021). Genome-wide impact of hydrogen peroxide on maintenance DNA methylation in replicating cells. Epigenetics & Chromatin, 14(1), 17. doi: 10.1186/s13072-021-00388-6 Journal - Research Article
Nabais, M. F., Laws, S. M., Lin, T., Vallerga, C. L., Armstrong, N. J., Blair, I. P., … Anderson, T. J., … Kennedy, M., … Pearson, J., Pitcher, T. L., … McRae, A. F. (2021). Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biology, 22(1), 90. doi: 10.1186/s13059-021-02275-5 Journal - Research Article
Sinha, P., Cree, S. L., Miller, A. L., Pearson, J. F., & Kennedy, M. A. (2021). Transcriptional analysis of sodium valproate in a serotonergic cell line reveals gene regulation through both HDAC inhibition-dependent and independent mechanisms. Pharmacogenomics Journal, 21, 359-375. doi: 10.1038/s41397-021-00215-x Journal - Research Article
Noble, A. J., Pearson, J. F., Boden, J. M., Horwood, L. J., Gemmell, N. J., Kennedy, M. A., & Osborne, A. J. (2021). A validation of Illumina EPIC array system with bisulfite-based amplicon sequencing. PeerJ, 9, e10762. doi: 10.7717/peerj.10762 Journal - Research Article
Munn-Chernoff, M. A., Johnson, E. C., Chou, Y.-L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., … Boden, J. M., … Horwood, L. J., … Pearson, J. F., … Jordan, J., Kennedy, M. A., … Agrawal, A. (2021). Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. Addiction Biology, 26, e12880. doi: 10.1111/adb.12880 Journal - Research Article
Kee, P. S., Chin, P. K. L., Kennedy, M. A., & Maggo, S. D. S. (2020). Pharmacogenetics of statin-induced myotoxicity. Frontiers in Genetics, 11, 575678. doi: 10.3389/fgene.2020.575678 Journal - Research Other
Noble, A., Pearson, J., Boden, J., Horwood, J., Kennedy, M., & Osborne, A. (2020). Understanding the interaction between maternal tobacco use during pregnancy and adult offspring with conduct disorder. New Zealand Medical Journal, 133(1524), (pp. 144). Retrieved from https://www.nzma.org.nz/journal Conference Contribution - Published proceedings: Abstract
Johnson, E. C., Demontis, D., Thorgeirsson, T. E., Walters, R. K., Polimanti, R., Hatoum, A. S., … Boden, J., … Pearson, J. F., … Horwood, J., … Kennedy, M. A., … Agrawal, A. (2020). A large-scale genome-wide association study meta-analysis of cannabis use disorder. Lancet Psychiatry, 7, 1032-1045. doi: 10.1016/S2215-0366(20)30339-4 Journal - Research Article
Adehin, A., Kennedy, M. A., Soyinka, J. O., Alatise, O. I., Olasehinde, O., & Bolaji, O. O. (2020). Breast cancer and tamoxifen: A Nigerian perspective to effective personalised therapy. Breast Cancer, 12, 123-130. doi: 10.2147/BCTT.S266314 Journal - Research Other
Cree, S. L., Chua, E. W., Crowther, J., Dobson, R. C. J., & Kennedy, M. A. (2020). G-quadruplex structures bind to EZ-Tn5 transposase. Biochimie, 177, 190-197. doi: 10.1016/j.biochi.2020.07.022 Journal - Research Article
Schierding, W., Farrow, S., Fadason, T., Graham, O. E. E., Pitcher, T. L., Qubisi, S., … Anderson, T. J., Kennedy, M. A., … O'Sullivan, J. M. (2020). Common variants coregulate expression of GBA and modifier genes to delay Parkinson's disease onset. Movement Disorders, 35(8), 1346-1356. doi: 10.1002/mds.28144 Journal - Research Article
Bulik, C., Kennedy, M., & Wade, T. (2020). ANGI: Anorexia Nervosa Genetics Initiative. Twin Research & Human Genetics, 23, 135-136. doi: 10.1017/thg.2020.24 Journal - Research Article
Bryois, J., Skene, N. G., Folmann Hansen, T., Kogelman, L. J. A., Watson, H. J., Liu, Z., … Eating Disorders Working Group of the Psychiatric Genomics Consortium, including Boden, J., … Jordan, J., … Kennedy, M., … Pearson, J., … Sullivan, P. F. (2020). Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease. Nature Genetics, 52, 482-493. doi: 10.1038/s41588-020-0610-9 Journal - Research Article
Osborne, A. J., Pearson, J. F., Noble, A. J., Gemmell, N. J., Horwood, L. J., Boden, J. M., … Kennedy, M. A. (2020). Genome-wide DNA methylation analysis of heavy cannabis exposure in a New Zealand longitudinal cohort. Translational Psychiatry, 10, 114. doi: 10.1038/s41398-020-0800-3 Journal - Research Article
Vallerga, C. L., Zhang, F., Fowdar, J., McRae, A. F., Qi, T., Nabais, M. F., … Kennedy, M., … Gratten, J. (2020). Analysis of DNA methylation associates the cystine-glutamate antiporter SLC7A11 with risk of Parkinson's disease. Nature Communications, 11, 1238. doi: 10.1038/s41467-020-15065-7 Journal - Research Article
Nofziger, C., Turner, A. J., Sangkuhl, K., Whirl-Carrillo, M., Agúndez, J. A. G., Black, J. L., … Kennedy, M. A., … Gaedigk, A. (2020). PharmVar GeneFocus: CYP2D6. Clinical Pharmacology & Therapeutics, 107(1), 154-170. doi: 10.1002/cpt.1643 Journal - Research Other
Slow, S., Pearson, J. F., Florkowski, C. M., Elder, P. A., Lewis, J. G., Kennedy, M. A., & Murdoch, D. R. (2020). Effect of genetic factors on the response to vitamin D3 supplementation in the VIDARIS randomised controlled trial. Nutrition, 75-76, 110761. doi: 10.1016/j.nut.2020.110761 Journal - Research Article
Searchfield, G. D., Poppe, T. N. E. R., Durai, M., Jensen, M., Kennedy, M. A., Maggo, S., Miller, A. L., … Russell, B. R., … Wise, K. (2020). A proof-of-principle study of the short-term effects of 3,4-methylenedioxymethamphetamine (MDMA) on tinnitus and neural connectivity. International Journal of Neuroscience, 130(7), 671-682. doi: 10.1080/00207454.2019.1702544 Journal - Research Article
Graham, O. E. E., Pitcher, T. L., Liau, Y., Miller, A. L., Dalrymple-Alford, J. C., Anderson, T. J., & Kennedy, M. A. (2020). Nanopore sequencing of the glucocerebrosidase (GBA) gene in a New Zealand Parkinson's disease cohort. Parkinsonism & Related Disorders, 70, 36-41. doi: 10.1016/j.parkreldis.2019.11.022 Journal - Research Article
Heft, I. E., Mostovoy, Y., Levy-Sakin, M., Ma, W., Stevens, A. J., Pastor, S., … Kennedy, M. A., … Sikela, J. M. (2020). The driver of extreme human-specific Olduvai repeat expansion remains highly active in the human genome. Genetics, 214, 179-191. doi: 10.1534/genetics.119.302782 Journal - Research Article
Doudney, K., Lacey, C. J., Bridgman, P. G., Mulder, R. T., Zarifeh, J. J., Kimber, B., Cadzow, M., Black, M. A., Merriman, T. R., … Pearson, J. F., Cameron, V. A., & Kennedy, M. A. (2019). Rare copy number variants involving cardiac function and development genes detected in earthquake induced takotsubo cardiomyopathy patients. European Journal of Human Genetics, 27(Suppl. 1), (pp. 160). doi: 10.1038/s41431-019-0407-4 Conference Contribution - Published proceedings: Abstract
Pearson, J., Osborne, A., Noble, A., Kennedy, M., Horwood, J., & Boden, J. (2019, August-September). Epigenetic impact of cannabis use in the Christchurch Health and Development Study. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Noble, A., Pearson, J., Boden, J., Horwood, J., Kennedy, M., & Osborne, A. (2019, August-September). Understanding the relationship between maternal tobacco smoking and offspring conduct disorder: Are metastable epialleles present? Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. (2019, October). Genetics as a key to understanding and improved treatment of mental disorders. Verbal presentation at the Otago Spotlight Series: Mental Health Research, Wellington, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Liu, W., Liau, Y., Maggo, S., Doogue, M., & Kennedy, M. (2019). Exploring combinatorial genetic contributions to a serious adverse drug reaction. Proceedings of the MapNet Meeting. (pp. 28). Retrieved from http://mapnet2019.nz/ Conference Contribution - Published proceedings: Abstract
Maggo, S., Kennedy, M., Barczyk, Z., Miller, A., Rucklidge, J., Mulder, R., & Foulds, J. (2019). Pharmacogenetic variants and psychological factors do not explain self-reported antidepressant side effects. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) and the Population Approach Group of Australia and New Zealand (PAGANZ) Joint Scientific Meeting: Shared Horizons: Optimizing Drug Response to Improve Patient Outcomes. (pp. 66). Retrieved from https://www.asceptasm.com Conference Contribution - Published proceedings: Abstract
Munn-Chernoff, M. A., Johnson, E. C., Chou, Y.-L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., … Boden, J. M., … Horwood, L. J., … Pearson, J. F., … Jordan, J., Kennedy, M. A., … Agrawal, A. (2019). Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. bioRxiv. doi: 10.1101/741512 Working Paper; Discussion Paper; Technical Report
Osborne, A. J., Pearson, J. F., Noble, A. J., Gemmell, N. J., Horwood, L. J., Boden, J. M., … Kennedy, M. A. (2019). Genome-wide DNA methylation analysis of heavy cannabis exposure in a New Zealand longitudinal cohort. bioRxiv. Retrieved from https://www.biorxiv.org/content/10.1101/829598v2.supplementary-material Working Paper; Discussion Paper; Technical Report
Maggo, S., Kennedy, M. A., Barczyk, Z. A., Miller, A. L., Rucklidge, J. J., Mulder, R. T., & Foulds, J. A. (2019). Common CYP2D6, CYP2C9, and CYP2C19 gene variants, health anxiety, and neuroticism are not associated with self-reported antidepressant side effects [Brief report]. Frontiers in Genetics, 10, 1199. doi: 10.3389/fgene.2019.01199 Journal - Research Other
Walker, L. C., Lattimore, V. L., Kvist, A., Kleiblova, P., Zemankova, P., de Jong, L., Wiggins, G. A. R., Hakkaart, C., Cree, S. L., … Kennedy, M. A., … de la Hoya, M. (2019). Comprehensive assessment of BARD1 messenger ribonucleic acid splicing with implications for variant classification. Frontiers in Genetics, 10, 1139. doi: 10.3389/fgene.2019.01139 Journal - Research Article
Maggo, S. D. S., Sycamore, K. L. V., Miller, A. L., & Kennedy, M. A. (2019). The three ps: Psychiatry, pharmacy, and pharmacogenomics, a brief report from New Zealand. Frontiers in Psychiatry, 10, 690. doi: 10.3389/fpsyt.2019.00690 Journal - Research Article
Liau, Y., Cree, S. L., Maggo, S., Miller, A. L., Pearson, J. F., Gladding, P. A., & Kennedy, M. A. (2019). A multiplex pharmacogenetics assay using the MinION nanopore sequencing device. Pharmacogenetics & Genomics, 29(9), 207-215. doi: 10.1097/fpc.0000000000000385 Journal - Research Article
Liau, Y., Maggo, S., Miller, A. L., Pearson, J. F., Kennedy, M. A., & Cree, S. L. (2019). Nanopore sequencing of the pharmacogene CYP2D6 allows simultaneous haplotyping and detection of duplications. Pharmacogenomics, 20(14), 1033-1047. doi: 10.2217/pgs-2019-0080 Journal - Research Article
Chua, E. W., Harger, S. P., & Kennedy, M. A. (2019). Metoclopramide-induced acute dystonic reactions may be associated with the CYP2D6 poor metabolizer status and pregnancy-related hormonal changes. Frontiers in Pharmacology, 10, 931. doi: 10.3389/fphar.2019.00931 Journal - Research Other
Zhang, Q., Vallerga, C. L., Walker, R. M., Lin, T., Henders, A. K., Montgomery, G. W., … Kennedy, M., Pitcher, T., Pearson, J., … Anderson, T., … Visscher, P. M. (2019). Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing. Genome Medicine, 11(1), 54. doi: 10.1186/s13073-019-0667-1 Journal - Research Article
Prickett, T. C. R., Spittlehouse, J. K., Miller, A. L., Liau, Y., Kennedy, M. A., Cameron, V. A., Pearson, J. F., Boden, J. M., Troughton, R. W., & Espiner, E. A. (2019). Contrasting signals of cardiovascular health among natriuretic peptides in subjects without heart disease. Scientific Reports, 9, 12108. doi: 10.1038/s41598-019-48553-y Journal - Research Article
Sinha, P., Cree, S., Balasubramanian, D., Pearson, J., & Kennedy, M. (2019). Gene expression effects of valproic acid in a serotonergic cell line. European Neuropsychopharmacology, 29(Suppl. 4), (pp. S1248-S1249). doi: 10.1016/j.euroneuro.2018.08.331 Conference Contribution - Published proceedings: Abstract
Watson, H. J., Yilmaz, Z., Thornton, L. M., Hübel, C., Coleman, J. R. I., Gaspar, H. A., … Roberts, M., … Boden, J. M., … Horwood, L. J., … Pearson, J. F., … Jordan, J., Kennedy, M., … Bulik, C. M. (2019). Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics, 51, 1207-1214. doi: 10.1038/s41588-019-0439-2 Journal - Research Article
Stevens, A. J., Purcell, R. V., Darling, K. A., Eggleston, M. J. F., Kennedy, M. A., & Rucklidge, J. J. (2019). Human gut microbiome changes during a 10 week randomised control trial for micronutrient supplementation in children with attention deficit hyperactivity disorder. Scientific Reports, 9, 10128. doi: 10.1038/s41598-019-46146-3 Journal - Research Article
Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Attention Deficit/Hyperactivity Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Autism Spectrum Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Bipolar Disorder Working Group of the PGC, Eating Disorder Working Group of the PGC, including Kennedy, M. A., Major Depressive Disorder Working Group of the PGC, Obsessive Compulsive Disorders and Tourette Syndrome Working Group of the PGC, Schizophrenia CLOZUK, Substance Use Disorder Working Group of the PGC, including Horwood, L. J., Pearson, J. F., … Polderman, T. J. C. (2019). Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls. Psychological Medicine, 49(7), 1166-1173. doi: 10.1017/S0033291718002039 Journal - Research Article
Reynolds, R. H., Botía, J., Nalls, M. A., International Parkinson's Disease Genomics Consortium (IPDGC), including System Genomics of Parkinson's Disease (SGPD), Anderson, T., … Kennedy, M., Pearson, J., … Ryten, M. (2019). Moving beyond neurons: The role of cell type-specific gene regulation in Parkinson's disease heritability. npj Parkinson's Disease, 5, 6. doi: 10.1038/s41531-019-0076-6 Journal - Research Article
Watson, G. M., Chan, C. W., Belluscio, L., Doudney, K., Lacey, C. J., Kennedy, M. A., & Bridgman, P. (2019). Comparing the variants of takotsubo syndrome: An observational study of the ECG and structural changes from a New Zealand tertiary hospital. BMJ Open, 9(5), e025253. doi: 10.1136/bmjopen-2018-025253 Journal - Research Article
Osborne, A., Pearson, J., Gemmell, N., Boden, J., Horwood, J., & Kennedy, M. (2019). Methylome impacts of cannabis use in the Christchurch Health and Development Study. European Neuropsychopharmacology, 29(Suppl. 3), (pp. S851). doi: 10.1016/j.euroneuro.2017.08.125 Conference Contribution - Published proceedings: Abstract
Balasubramanian, D., Pearson, J. F., & Kennedy, M. A. (2019). Gene expression effects of lithium and valproic acid in a serotonergic cell line. Physiological Genomics, 51, 43-50. doi: 10.1152/physiolgenomics.00069.2018 Journal - Research Article
Liau, Y., Chua, I., Kennedy, M. A., & Maggo, S. (2019). Pharmacogenetics of angiotensin-converting enzyme inhibitor-induced angioedema. Clinical & Experimental Allergy, 49, 142-154. doi: 10.1111/cea.13326 Journal - Research Other
Richards, A., Horwood, J., Boden, J., Kennedy, M., Sellers, R., Riglin, L., … Harold, G. T. (2019). Associations between schizophrenia genetic risk, anxiety disorders and manic/hypomanic episode in a longitudinal population cohort study. British Journal of Psychiatry, 214, 96-102. doi: 10.1192/bjp.2018.227 Journal - Research Article
Gardner, R. J. M., Crozier, I. G., Binfield, A. L., Love, D. R., Lehnert, K., Gibson, K., … Jones, P. P., … Kennedy, M. A., & Skinner, J. R. (2019). Penetrance and expressivity of the R858H CACNA1C variant in a five-generation pedigree segregating an arrhythmogenic channelopathy. Molecular Genetics & Genomic Medicine, 7(1), e00476. doi: 10.1002/mgg3.476 Journal - Research Article
Rucklidge, J. J., Eggleston, M. J. F., Darling, K., Stevens, A., Kennedy, M., & Frampton, C. M. (2019). Can we predict treatment response in children with ADHD to a vitamin-mineral supplement? An investigation into pre-treatment nutrient serum levels, MTHFR status, clinical correlates and demographic variables. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 89, 181-192. doi: 10.1016/j.pnpbp.2018.09.007 Journal - Research Article
Adehin, A., Adeagbo, B. A., Kennedy, M. A., Bolaji, O. O., Olugbade, T. A., Bolarinwa, R. A., & Durosinmi, M. A. (2019). Inter-individual variation in imatinib disposition: Any role for prevalent variants of CYP1A2, CYP2C8, CYP2C9, and CYP3A5 in Nigerian CML patients? Leukemia & Lymphoma, 60(1), 216-221. doi: 10.1080/10428194.2018.1466291 Journal - Research Article
Sinha, P., Cree, S., Miller, A. L., Pearson, J. F., & Kennedy, M. A. (2018, August). Gene expression effects of sodium valproate in a serotonergic cell line. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Walters, R. K., Polimanti, R., Johnson, E. C., McClintick, J. N., Adams, M. J., Adkins, A. E., … Kennedy, M. A., … Pearson, J. F., … Agrawal, A. (2018). Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nature Neuroscience, 21(12), 1656-1669. doi: 10.1038/s41593-018-0275-1 Journal - Research Article
Adehin, A., Bolaji, O. O., Maggo, S., & Kennedy, M. A. (2018). Genetic polymorphism of CYP2C9 and VKORC1 in the Nigerian population: Significance for warfarin therapy in the population. Polish Annals of Medicine, 25(2), 180-183. doi: 10.29089/2017.17.00041 Journal - Research Article
Das, A., Morison, I., Kennedy, M., & Vissers, M. (2018, April). The potential use of ascorbate as an epigenetic therapeutic in acute myeloid leukaemia by enhancing 2-oxoglutarate dependent dioxygenase activity. Poster session presented at the Keystone Symposium: Therapeutic Targeting of Hypoxia-Sensitive Pathways, Oxford, UK. Conference Contribution - Poster Presentation (not in published proceedings)
Thornton, L. M., Munn-Chernoff, M. A., Baker, J. H., Juréus, A., Parker, R., Henders, A. K., … Horwood, L. J., Boden, J. M., Pearson, J. F., … Jordan, J., Kennedy, M. A., … Bulik, C. M. (2018). The Anorexia Nervosa Genetics Initiative (ANGI): Overview and methods. Contemporary Clinical Trials, 74, 61-69. doi: 10.1016/j.cct.2018.09.015 Journal - Research Article
Stevens, A. J., Rucklidge, J. J., Darling, K. A., Eggleston, M. J. F., Pearson, J. F., & Kennedy, M. A. (2018). Methylomic changes in response to micronutrient supplementation and MTHFR genotype. Epigenomics, 10(9), 1201-1214. doi: 10.2217/epi-2018-0029 Journal - Research Article
Kennedy, M. A. (2018). A genome project for Māori and Pasifika: Charting a path to equity in genomic medicine for Aotearoa. New Zealand Medical Journal, 131(1480), 8-10. Retrieved from https://www.nzma.org.nz/journal Journal - Research Other
Gurney, J. K., Stanley, J., McGlynn, K., Richiardi, L., Shaw, C., Edwards, R., Merriman, T. R., Robson, B., … McLeod, M., Kennedy, M. A., & Sarfati, D. (2018). Testicular Cancer in New Zealand (TCNZ) study: Protocol for a national case-control study. BMJ Open, 8, e025212. doi: 10.1136/bmjopen-2018-025212 Journal - Research Other
King, M., Kennedy, M., Rhodes, S., & Brown, A. (2018, June). Opening the doors on animal research. Panel discussion at the Australian and New Zealand Laboratory Animal Association (ANZLAA) New Zealand Branch Winter Meeting, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Maggo, S., Liau, Y., Doogue, M., & Kennedy, M. (2018). Understanding drug reactions using genome sequencing (UDRUGS) study: A New Zealand initiative to investigate the genetics of ADRs. Basic & Clinical Pharmacology & Toxicology, 123(Suppl. 1), (pp. 3). doi: 10.1111/bcpt.13020 Conference Contribution - Published proceedings: Abstract
Roberts, R. L., Wallace, M. C., Seinen, M. L., van Bodegraven, A. A., Krishnaprasad, K., Jones, G. T., van Rij, A. M., … Kennedy, M. A., … Gearry, R. B., … Barclay, M. (2018). Nonsynonymous polymorphism in guanine monophosphate synthetase is a risk factor for unfavorable thiopurine metabolite ratios in patients with inflammatory bowel disease. Inflammatory Bowel Diseases, 24(12), 2606-2612. doi: 10.1093/ibd/izy163 Journal - Research Article
Lacey, C. J., Doudney, K., Bridgman, P. G., George, P. M., Mulder, R. T., Zarifeh, J. J., Kimber, B., Cadzow, M. J., Black, M. A., Merriman, T. R., … Pearson, J. F., Cameron, V. A., & Kennedy, M. A. (2018). Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy. Scientific Reports, 8, 7548. doi: 10.1038/s41598-018-25827-5 Journal - Research Article
Ton, K. N. T., Cree, S. L., Gronert-Sum, S. J., Merriman, T. R., Stamp, L. K., & Kennedy, M. A. (2018). Multiplexed nanopore sequencing of HLA-B locus in Māori and Pacific Island samples. Frontiers in Genetics, 9, 152. doi: 10.3389/fgene.2018.00152 Journal - Research Article
Stevens, A. J., Rucklidge, J. J., & Kennedy, M. A. (2018). Epigenetics, nutrition and mental health: Is there a relationship? [Review]. Nutritional Neuroscience, 21(9), 602-613. doi: 10.1080/1028415x.2017.1331524 Journal - Research Article
Culverhouse, R. C., Saccone, N. L., Horton, A. C., Ma, Y., Anstey, K. J., Banaschewski, T., … Horwood, J., … Fergusson, D. M., … Kennedy, M., … Bierut, L. J. (2018). Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. Molecular Psychiatry, 23, 133-142. doi: 10.1038/mp.2017.44 Journal - Research Article
Osborne, A., Pearson, J., Hore, T., Horwood, J., Macartney-Coxson, D., Gemmell, N., & Kennedy, M. (2017). Identifying methylome changes in response to heavy, long-term cannabis use, in a large longitudinal cohort. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 519. Retrieved from http://gen2017.w.events4you.currinda.com Conference Contribution - Published proceedings: Abstract
Whitefield, J., & Kennedy, M. (2017). Above the threshold. Junctures, 2017(18), 9-18. Journal - Research Article
Cree, S., Maggo, S., Slow, S., Ton, K., de Jong, L., Anderson, T., Pearson, J., Miller, A., Walker, L., Murdoch, D., & Kennedy, M. (2017). Long read nanopore sequencing in the laboratory. Proceedings of the MapNet Conference. Retrieved from http://scienceevents.co.nz/mapnet/ Conference Contribution - Published proceedings: Abstract
Lacey, C. J., Doudney, K., Bridgman, P. G., George, P. M., Mulder, R. T., Zarifeh, J. A., Kimber, B., Cadzow, M. J., Black, M. A., Merriman, T. R., … Pearson, J. F., Cameron, V. A., & Kennedy, M. A. (2017). Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy. bioRxiv. doi: 10.1101/144675 Working Paper; Discussion Paper; Technical Report
Maggo, S. D. S., Chua, E. W., Chin, P., Cree, S., Pearson, J., Doogue, M., & Kennedy, M. A. (2017). A New Zealand platform to enable genetic investigation of adverse drug reactions. New Zealand Medical Journal, 130(1466), 62-69. Retrieved from http://www.nzma.org.nz/journal Journal - Research Article
de Jong, L. C., Cree, S., Lattimore, V., Wiggins, G. A. R., Spurdle, A. B., kConFab Investigators, Miller, A., Kennedy, M. A., & Walker, L. C. (2017). Nanopore sequencing of full-length BRCA1 mRNA transcripts reveals co-occurrence of known exon skipping events. Breast Cancer Research, 19, 127. doi: 10.1186/s13058-017-0919-1 Journal - Research Article
Das, A., Morison, I., Kennedy, M., & Vissers, M. (2017, October). The potential use of ascorbate as an epigenetic drug in acute myeloid leukaemia. Poster session presented at the New Zealand Society for Oncology (NZSO) Conference, Auckland, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Kennedy, M. A., Maggo, S. D. S., Foulds, J., Luty, S., Chua, E. W., Cree, S., Ton, K., Liau, Y., Miller, A. L., Chin, P., … Doogue, M. (2017). DNA banking and genetic analysis of adverse drug reactions in the New Zealand healthcare setting. Proceedings of the American Society of Human Genetics (ASHG) Annual Meeting. 2123. Retrieved from http://www.ashg.org/2017meeting/ Conference Contribution - Published proceedings: Abstract
Kennedy, M. A., Cree, S. L., Miller, A. L., Pearson, J., Maggo, S., Liau, Y., Ton, K., de Jong, L., & Walker, L. C. (2017, September). The MinION nanopore sequencer: Toy or tool? Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Liau, Y., Cree, S. M., Maggo, S., Miller, A. L., Pearson, J., & Kennedy, M. A. (2017, September). A nanopore sequencing-based multiplex assay for pharmacogenetics of clopidogrel and warfarin. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Osborne, A. J., Pearson, J. F., Horwood, J., Hore, T., Macartney-Coxson, D., Gemmell, N. J., & Kennedy, M. A. (2017, September). Cannabis use and epigenetics: EPIC insights into the human methylome. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Duncan, L., Yilmaz, Z., Gaspar, H., Walters, R., Goldstein, J., Anttila, V., … Eating Disorders Working Group of the Psychiatric Genomics Consortium, including Jordan, J., Kennedy, M., … Bulik, C. M. (2017). Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa. American Journal of Psychiatry, 174(9), 850-858. doi: 10.1176/appi.ajp.2017.16121402 Journal - Research Article
Adehin, A., Bolaji, O. O., Maggo, S., & Kennedy, M. A. (2017). Relationship between metabolic phenotypes and genotypes of CYP1A2 and CYP2A6 in the Nigerian population. Drug Metabolism & Personalized Therapy, 32(1), 39-47. doi: 10.1515/dmpt-2016-0041 Journal - Research Article
Adehin, A., Bolaji, O. O., & Kennedy, M. A. (2017). Polymorphisms in CYP2C8 and CYP3A5 genes in the Nigerian population. Drug Metabolism & Pharmacokinetics, 32(3), 189-191. doi: 10.1016/j.dmpk.2016.09.001 Journal - Research Article
Adehin, A., Bolaji, O. O., Kennedy, M. A., & Adeagbo, B. A. (2017). Allele frequencies of thiopurine S-methyltransferase (TPMT) variants in the Nigerian population. Polish Annals of Medicine, 24(2), 144-147. doi: 10.1016/j.poamed.2016.06.007 Journal - Research Article
Stevens, A. J., & Kennedy, M. A. (2017). Methylated cytosine maintains G-quadruplex structures during polymerase chain reaction and contributes to allelic dropout. Biochemistry, 56(29), 3691-3698. doi: 10.1021/acs.biochem.7b00480 Journal - Research Article
Chua, E. W., Maggo, S., & Kennedy, M. A. (2017). Long fragment polymerase chain reaction. In L. Domingues (Ed.), PCR: Methods in molecular biology (Vol. 1620). (pp. 65-74). New York, NY: Springer. doi: 10.1007/978-1-4939-7060-5_3 Chapter in Book - Research
Kirk, K. M., Martin, F. C., Mao, A., Parker, R., Maguire, S., Thornton, L. M., … Jordan, J., Kennedy, M. A., … Martin, N. G. (2017). The Anorexia Nervosa Genetics Initiative: Study description and sample characteristics of the Australian and New Zealand arm. Australian & New Zealand Journal of Psychiatry, 51(6), 583-594. doi: 10.1177/0004867417700731 Journal - Research Article
Shchepetkina, A. A., Hock, B. D., Miller, A., Kennedy, M. A., & Gieseg, S. P. (2017). Effect of 7,8-dihydroneopterin mediated CD36 down regulation and oxidant scavenging on oxidised low-density lipoprotein induced cell death in human macrophages. International Journal of Biochemistry & Cell Biology, 87, 27-33. doi: 10.1016/j.biocel.2017.03.017 Journal - Research Article
Bagshaw, A. T. M., Horwood, L. J., Fergusson, D. M., Gemmell, N. J., & Kennedy, M. A. (2017). Microsatellite polymorphisms associated with human behavioural and psychological phenotypes including a gene-environment interaction. BMC Medical Genetics, 18, 12. doi: 10.1186/s12881-017-0374-y Journal - Research Article
Stevens, A. J., Taylor, M. G., Pearce, F. G., & Kennedy, M. A. (2017). Allelic dropout during polymerase chain reaction due to G-quadruplex structures and DNA methylation is widespread at imprinted human loci. Genes Genomes Genetics, 7(3), 1019-1025. doi: 10.1534/g3.116.038687 Journal - Research Article
Stevens, A. J., & Kennedy, M. A. (2017). Structural analysis of G-quadruplex formation at the human MEST promoter. PLoS ONE, 12(1), e0169433. doi: 10.1371/journal.pone.0169433 Journal - Research Article
Appleby, S., Pearson, J. F., Aitchison, A., Spittlehouse, J. K., Joyce, P. R., & Kennedy, M. A. (2017). Mean telomere length is not associated with current health status in a 50-year-old population sample. American Journal of Human Biology, 29(1), e22906. doi: 10.1002/ajhb.22906 Journal - Research Article
Stevens, A. J., Appleby, S., & Kennedy, M. A. (2016). Many commercial hot-start polymerases demonstrate activity prior to thermal activation. Biotechniques, 61(6), 293-296. doi: 10.2144/000114481 Journal - Research Other
Maggo, S., Young, J., Lehnert, K., George, P., & Kennedy, M. A. (2016). Statin induced myalgia, is there a genetic link? Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists and the Molecular Pharmacology of G Protein-Coupled Receptors (ASCEPT-MPGPCR) Joint Scientific Meeting. 334. Retrieved from http://www.asceptasm.com/ Conference Contribution - Published proceedings: Abstract
Stevens, A., Appleby, S., & Kennedy, M. (2016, August-September). Many commercial hot-start polymerases demonstrate activity prior to thermal activation. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Maggo, S. D. S., Young, J., Lehnert, K., George, P., & Kennedy, M. A. (2016). Understanding adverse drug reactions using genome sequencing (UDRUGS): A focus on statin induced myalgia. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) Annual Scientific Meeting. (pp. 44). Retrieved from http://www.queenstownresearchweek.org/index.php/ascept-nz/ Conference Contribution - Published proceedings: Abstract
Cree, S. L., Fredericks, R., Miller, A., Pearce, F. G., Filichev, V., Fee, C., & Kennedy, M. A. (2016). DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro. FEBS Letters, 590(17), 2870-2883. doi: 10.1002/1873-3468.12331 Journal - Research Article
Stevens, A. J., Kennedy, H. L., & Kennedy, M. A. (2016). Fluorescence methods for probing G-quadruplex structure in single- and double-stranded DNA. Biochemistry, 55(26), 3714-3725. doi: 10.1021/acs.biochem.6b00327 Journal - Research Article
Foulds, J. A., Maggo, S. D. S., & Kennedy, M. A. (2016). Personalised prescribing in psychiatry: Has pharmacogenomics delivered on its promise? Australian & New Zealand Journal of Psychiatry, 50(6), 509-510. doi: 10.1177/0004867416640099 Journal - Research Other
Osborne, A. J., Negro, S. S., Chilvers, B. L., Robertson, B. C., Kennedy, M. A., & Gemmell, N. J. (2016). Genetic evidence of a population bottleneck and inbreeding in the endangered New Zealand sea lion, Phocarctos hookeri. Journal of Heredity, 107(5), 392-402. doi: 10.1093/jhered/esw015 Journal - Research Article
Chua, E. W., Cree, S. L., Ton, K. N. T., Lehnert, K., Shepherd, P., Helsby, N., & Kennedy, M. A. (2016). Cross-comparison of exome analysis, next-generation sequencing of amplicons, and the iPLEX® ADME PGx Panel for pharmacogenomic profiling. Frontiers in Pharmacology, 7, 1. doi: 10.3389/fphar.2016.00001 Journal - Research Article
Bridgman, P. G., Finsterer, J., Lacey, C., Kimber, B., Parkin, P. J., Miller, A. L., & Kennedy, M. A. (2016). CTG-repeat expansions in the DMPK gene do not cause takotsubo syndrome [Short communication]. International Journal of Cardiology, 203, 107-108. doi: 10.1016/j.ijcard.2015.10.112 Journal - Research Other
Maggo, S. D. S., Savage, R. L., & Kennedy, M. A. (2016). Impact of new genomic technologies on understanding adverse drug reactions. Clinical Pharmacokinetics, 55(4), 419-436. doi: 10.1007/s40262-015-0324-9 Journal - Research Article
Ton, K. N. T., Macmil, S., Rand, C., Stanton, J.-A., & Kennedy, M. A. (2015, August-September). A next generation sequencing PGx panel for predicting adverse drug reaction and unusual response. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Sinha, P., Balasubramanain, D., Pearson, J. F., & Kennedy, M. A. (2015, August-September). RNA-Seq analysis of gene expression changes caused by mood stabilizer drugs in a serotonergic cell line. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Jodczyk, S., Cree, S., & Kennedy, M. A. (2015, August-September). Trialling the MinION™ nanopore DNA sequencer for direct measurement of human telomere length. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Kennedy, M., Doudney, K., Bickley, V., Bridgman, P., Cameron, V., Cadzow, M., Black, M., Merriman, T., … Miller, A., Zarifeh, J., Kimber, B., George, P., & Lacey, C. (2015, August-September). Genomes, earthquakes and broken hearts. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Stevens, A., & Kennedy, M. (2015, August-September). CpG Methylation increases G-quadruplex re-association during PCR and influences genotyping of the imprinted MEST gene promoter. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Cree, S. L., Miller, A. L., Chua, E. W., Maggo, S., & Kennedy, M. A. (2015, August). Long-read nanopore Sequencing for the detection of genetic polymorphisms in the CYP2D6 gene. Verbal presentation at the 7th Annual New Zealand Next Generation Sequencing (NGS) Conference, Palmerston North, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Maggo, S. D. S., Foulds, J., Luty, S. E., Miller, A. L., Kennedy, H., Doogue, M., & Kennedy, M. A. (2015, September). Understanding adverse drug reactions using genome sequencing (UDRUGS): Recent cases on SSRIs and SNRIs. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M., Jordan, J., Martin, N., Wade, T., Montgomery, G., & Bulik, C. (2015, August). The Anorexia Nervosa Genetics Initiative (ANGI): Australia and New Zealand join forces. Poster session presented at the 13th Australia & New Zealand Academy for Eating Disorders (ANZAED) Annual Conference, Surfers Paradise, Australia. Conference Contribution - Poster Presentation (not in published proceedings)
Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., … Horwood, J., Fergusson, D. M., Kennedy, M. A., … Sattar, N. (2015). Heavier smoking may lead to a relative increase in waist circumference: Evidence for a causal relationship from a Mendelian randomisation meta-analysis: The CARTA consortium. BMJ Open, 5(8), e008808. doi: 10.1136/bmjopen-2015-008808 Journal - Research Article
Adkins, D. E., Clark, S. L., Copeland, W. E., Kennedy, M., Conway, K., Angold, A., … Fergusson, D. M., Horwood, L. J., … Costello, E. J. (2015). Genome-wide meta-analysis of longitudinal alcohol consumption across youth and early adulthood. Twin Research & Human Genetics, 18(4), 335-347. doi: 10.1017/thg.2015.36 Journal - Research Article
Balasubramanain, D., Deng, A. X., Doudney, K., Hampton, M. B., & Kennedy, M. A. (2015). Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line. Neuropharmacology, 99, 79-88. doi: 10.1016/j.neuropharm.2015.06.018 Journal - Research Article
Osborne, A. J., Pearson, J., Chilvers, B. L., Kennedy, M. A., & Gemmell, N. J. (2015). Examining the role of components of Slc11a1 (Nramp1) in the susceptibility of New Zealand sea lions (Phocarctos hookeri) to disease. PLoS ONE, 10(4), e0122703. doi: 10.1371/journal.pone.0122703 Journal - Research Article
Chua, E.-W., Miller, A. L., & Kennedy, M. A. (2015). Choice of PCR microtube can impact on the success of long-range PCRs. Analytical Biochemistry, 477, 115-117. doi: 10.1016/j.ab.2015.02.023 Journal - Research Other
Chua, E. W., Cree, S., Barclay, M. L., Doudney, K., Lehnert, K., Aitchison, A., & Kennedy, M. A. (2015). Exome sequencing and array-based comparative genomic hybridisation analysis of preferential 6-methylmercaptopurine producers. Pharmacogenomics Journal, 15, 414-421. doi: 10.1038/tpj.2015.9 Journal - Research Article
Osborne, A. J., Pearson, J., Negro, S. S., Chilvers, B. L., Kennedy, M. A., & Gemmell, N. J. (2015). Heterozygote advantage at MHC DRB may influence response to infectious disease epizootics. Molecular Ecology, 24, 1419-1432. doi: 10.1111/mec.13128 Journal - Research Article
Foulds, J. A., Ton, K., Kennedy, M. A., Adamson, S. J., Mulder, R. T., & Sellman, J. D. (2015). OPRM1 genotype and naltrexone response in depressed alcohol-dependent patients. Pharmacogenetics & Genomics, 25(5), 270-273. doi: 10.1097/fpc.0000000000000128 Journal - Research Article
Larsen, P. D., Johnston, L. R., Holley, A., La Flamme, A., Smyth, L., Chua, E. W., Kennedy, M. A., & Harding, S. A. (2015). Prevalence and significance of CYP2C19*2 and CYP2C19*17 alleles in a New Zealand acute coronary syndrome population. Internal Medicine Journal, 45(5), 537-545. doi: 10.1111/imj.12698 Journal - Research Article
Jodczyk, S., Pearson, J. F., Aitchison, A., Miller, A. L., Hampton, M. B., & Kennedy, M. A. (2015). Telomere length measurement on the Roche LightCycler 480 platform. Genetic Testing & Molecular Biomarkers, 19(2), 63-68. doi: 10.1089/gtmb.2014.0208 Journal - Research Article
Davis, J. M., Searles, V. B., Anderson, N., Keeney, J., Raznahan, A., Horwood, L. J., Fergusson, D. M., Kennedy, M. A., … Sikela, J. M. (2015). DUF1220 copy number is linearly associated with increased cognitive function as measured by total IQ and mathematical aptitude scores. Human Genetics, 134(1), 67-75. doi: 10.1007/s00439-014-1489-2 Journal - Research Article
Jodczyk, S., Pearson, J. F., Fergusson, D. M., Horwood, L. J., Spittlehouse, J. K., Joyce, P. R., Hampton, M. B., & Kennedy, M. A. (2014). No association between telomere length and exposure to life course stress or adversity in two longitudinal New Zealand cohorts. Proceedings of the American Society of Human Genetics (ASHG) Annual Meeting. 1325M. Retrieved from http://www.ashg.org/ Conference Contribution - Published proceedings: Abstract
Kennedy, M. (2014, November). Genomic tools for analysis of adverse drug reactions. Verbal presentation at the 10th Annual Carney Pharmacogenomics Symposium, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Taylor, A. E., Morris, R. W., Fluharty, M. E., Bjorngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., … Horwood, J., Fergusson, D. M., Kennedy, M. A., … Sattar, N. (2014). Stratification by smoking status reveals a direct association of CHRNA5-A3-B4 genotype with body mass index in never smokers. PLoS Genetics, 10(12), e1004799. doi: 10.1371/journal.pgen.1004799 Journal - Research Article
Stevens, A. J., Stuffrein-Roberts, S., Cree, S. L., Gibb, A., Miller, A. L., Doudney, K., Aitchison, A., Eccles, M. R., Joyce, P. R., … Kennedy, M. A. (2014). G-quadruplex structures and CpG methylation cause drop-out of the maternal allele in polymerase chain reaction amplification of the imprinted MEST gene promoter. PLoS ONE, 9(12), e113955. doi: 10.1371/journal.pone.0113955 Journal - Research Article
Kennedy, M. (2014, August). G-quadruplex structures and allelic drop-out during PCR of the imprinted MEST gene promoter. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Taylor, A. E., Fluharty, M. E., Bjømgaard, J. H., Gabrielsen, M. E., Skorpen, F., Marioni, R. E., … Horwood, L. J., … Kennedy, M. A., … Munafò, M. R. (2014). Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: The CARTA consortium. BMJ Open, 4(10), e006141. doi: 10.1136/bmjopen-2014-006141 Journal - Research Article
Jodczyk, S., Pearson, J., Fergusson, D., Horwood, J., Spittlehouse, J., Joyce, P., Hampton, M., & Kennedy, M. (2014, September). No association between telomere length and exposure to life course stress in two longitudinal New Zealand cohorts. Poster session presented at the Division of Health Sciences Research Forum: Learning Different Research Languages, Dunedin, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Cree, S. L., & Kennedy, M. A. (2014). Relevance of G-quadruplex structures to pharmacogenetics. Frontiers in Pharmacology, 5, 160. doi: 10.3389/fphar.2014.00160 Journal - Research Article
Peterson, R. E., Maes, H. H., Eaves, L. J., Silberg, J. L., Adkins, D. E., Clark, S. L., … Kennedy, M., Fergusson, D. M., Horwood, L. J., … Conway, K. (2014). Polygenicity analysis of smoking behavior in adolescence. Proceedings of the Society for Research on Nicotine and Tobacco (SRNT) 20th Annual Meeting. (pp. 163-164). SRNT. Retrieved from http://www.srnt.org/conferences/past/index.cfm Conference Contribution - Published proceedings: Abstract
Maes, H. H., Peterson, R. E., Eaves, L. J., Silberg, J. L., Adkins, D. E., Clark, S. L., … Kennedy, M., Fergusson, D. M., Horwood, L. J., … Costello, E. J. (2014). A genome-wide meta-analytic study of smoking behavior in adolescents. Proceedings of the Society for Research on Nicotine and Tobacco (SRNT) 20th Annual Meeting. (pp. 159). SRNT. Retrieved from http://www.srnt.org/conferences/past/index.cfm Conference Contribution - Published proceedings: Abstract
Jodczyk, S., Pearson, J. F., Fergusson, D. M., Horwood, L. J., Spittlehouse, J. K., Joyce, P. R., Hampton, M. B., & Kennedy, M. A. (2014). Association between telomere length and life stress in two New Zealand cohorts. New Zealand Medical Journal, 127(1396). Retrieved from http://www.nzma.org.nz/journal Conference Contribution - Published proceedings: Abstract
Lacey, C., Mulder, R., Bridgman, P., Kimber, B., Zarifeh, J., Kennedy, M., & Cameron, V. (2014). Broken heart syndrome: Is it a psychosomatic disorder? Journal of Psychosomatic Research, 77(2), 158-160. doi: 10.1016/j.jpsychores.2014.05.003 Journal - Research Article
Jodczyk, S., Fergusson, D. M., Horwood, L. J., Pearson, J. F., & Kennedy, M. A. (2014). No association between mean telomere length and life stress observed in a 30 year birth cohort. PLoS ONE, 9(5), e97102. doi: 10.1371/journal.pone.0097102 Journal - Research Article
Joyce, P. R., Stephenson, J., Kennedy, M., Mulder, R. T., & McHugh, P. C. (2014). The presence of both serotonin 1A receptor (HTR1A) and dopamine transporter (DAT1) gene variants increase the risk of borderline personality disorder. Frontiers in Genetics, 4, 313. doi: 10.3389/fgene.2013.00313 Journal - Research Article
Stevens, A. J., Stuffrein-Roberts, S., Macmil, S., Gibb, A., Doudney, K., Miller, A. L., Bagshaw, A., Aitchison, A., Eccles, M. R., Joyce, P. R., … Kennedy, M. A. (2013). Allelic-dropout during PCR of the imprinted MEST promoter caused by interaction between G-quadruplex structures and DNA methylation. Proceedings of the 4th International Meeting on G-quadruplex Nucleic Acids: From Structure to Chemistry and Biology. 83. Retrieved from http://www.g4meeting2013.com/ Conference Contribution - Published proceedings: Abstract
Macmil, S. L., Fredericks, R., Miller, A., Fee, C., Filichev, V. V., & Kennedy, M. A. (2013). Structure based function: Investigating the role of G-quadruplex structures in de novo DNA methylation. Proceedings of the 4th International Meeting on G-quadruplex Nucleic Acids: From Structure to Chemistry and Biology. 79. Retrieved from http://www.g4meeting2013.com/ Conference Contribution - Published proceedings: Abstract
Kennedy, M. (2013, September). Understanding the genome to improve medicine. Verbal presentation at the Inaugural Genetics Week, Auckland, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. (2013). Just when will genetics revolutionise medicine: Part 1. Proceedings of the George Abbott Symposium. Retrieved from http://www.otago.ac.nz/george-abbott Conference Contribution - Published proceedings: Abstract
Kennedy, M., Joyce, P., & Begg, E. (2013). Carney Centre for Pharmacogenomics. In P. Joyce, G. Nicholls, K. Thomas & T. Wilkinson (Eds.), The Christchurch experience: 40 years of research and teaching. (pp. 100-104). Christchurch, New Zealand: University of Otago. Chapter in Book - Other
Kennedy, M. A., Chua, E. W., Macmil, S., Foulds, J., Barclay, M., Savage, R., … Miller, A. (2013, August). Genomic medicine and adverse drug reactions. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Chua, E. W., Macmil, S., Foulds, J., Barclay, M., Savage, R., Helsby, N. A., Miller, A., & Kennedy, M. A. (2013, August). Understanding adverse Drug Reactions or responses Using Genomic Sequencing (UDRUGS). Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Buffery, P. J., Barclay, M. L., Doogue, M. P., Moore, G. A., & Kennedy, M. A. (2013, August). Codeine, breastfeeding and infant narcosis: A cautionary case. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Chua, E. W., Foulds, J., Miller, A. L., & Kennedy, M. A. (2013). Novel CYP2D6 and CYP2C19 variants identified in a patient with adverse reactions towards venlafaxine monotherapy and dual therapy with nortriptyline and fluoxetine. Pharmacogenetics & Genomics, 23(9), 494-497. doi: 10.1097/FPC.0b013e328363688d Journal - Research Article
Johnston, L., Smyth, L., Kennedy, M., Holley, A., Sasse, A., La Flamme, A., Larsen, P., & Harding, S. (2013). High on treatment platelet reactivity is associated with a higher risk of MACE in ACS patients: Diabetes and loss of function genotype the driving forces. Heart, Lung & Circulation, 22(7), (pp. 561). doi: 10.1016/j.hlc.2013.04.035 Conference Contribution - Published proceedings: Abstract
Schluter, P. J., Spittlehouse, J. K., Cameron, V. A., Chambers, S., Gearry, R., Jamieson, H. A., Kennedy, M., Lacey, C. J., Murdoch, D. R., Pearson, J., Porter, R. J., Richards, M., Skidmore, P. M. L., Troughton, R., Vierck, E., & Joyce, P. R. (2013). Canterbury Health, Ageing and Life Course (CHALICE) study: Rationale, design and methodology. New Zealand Medical Journal, 126(1375). Retrieved from http://www.nzma.org.nz/journal Journal - Research Article
Trent, R. J., Cheong, P. L., Chua, E. W., & Kennedy, M. A. (2013). Progressing the utilisation of pharmacogenetics and pharmacogenomics into clinical care. Pathology, 45(4), 357-370. doi: 10.1097/PAT.0b013e328360b66e Journal - Research Article
Costello, E. J., Eaves, L., Sullivan, P., Kennedy, M., Conway, K., Adkins, D. E., … van den Oord, E. (2013). Genes, environments, and developmental research: Methods for a multi-site study of early substance abuse. Twin Research & Human Genetics, 16(2), 505-515. doi: 10.1017/thg.2013.6 Journal - Research Article
Osborne, A. J., Zavodna, M., Chilvers, B. L., Robertson, B. C., Negro, S. S., Kennedy, M. A., & Gemmell, N. J. (2013). Extensive variation at MHC DRBin the New Zealand sea lion (Phocarctos hookeri) provides evidence for balancing selection. Heredity, 111, 44-56. doi: 10.1038/hdy.2013.18 Journal - Research Article
Kennedy, M. (2013, February). DNA and disease: Following a common thread, University of Otago Christchurch Health Lecture Series. Christchurch, New Zealand. [Public Seminar]. Other Research Output
Kennedy, M. (2013, February). Drugs and the genome. Verbal presentation at the Christchurch Medical School 40th Anniversary Celebrations, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Appell, M. L., Berg, J., Duley, J., Evans, W. E., Kennedy, M. A., Lennard, L., … Coulthard, S. A. (2013). Nomenclature for alleles of the thiopurine methyltransferase gene. Pharmacogenetics & Genomics, 23, 242-248. doi: 10.1097/FPC.0b013e32835f1cc0 Journal - Research Article
Bagshaw, A. T. M., Horwood, L. J., Liu, Y., Fergusson, D. M., Sullivan, P. F., & Kennedy, M. A. (2013). No effect of genome-wide copy number variation on measures of intelligence in a New Zealand birth cohort. PLoS ONE, 8(1), e55208. doi: 10.1371/journal.pone.0055208 Journal - Research Article
Pearson, J. F., Fergusson, D. M., Horwood, L. J., Miller, A. L., Sullivan, P. F., Youfang, L. E., & Kennedy, M. A. (2013). Increased risk of major depression by childhood abuse is not modified by CNR1 genotype. American Journal of Medical Genetics Part B, 162(2), 224-226. doi: 10.1002/ajmg.b.32124 Journal - Research Other
Achram, H., Shaw, I. C., & Kennedy, M. (2012, September). DNA methylation as a potential biomarker of phthalate exposure. Poster session presented at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Jodczyk, S., Miller, A., Fergusson, D., Horwood, J., & Kennedy, M. (2012, March). Association between nicotine and alcohol dependence and short mean telomere length in a longitudinal birth cohort study. Poster session presented at the Human Genome Meeting (HUGO): Genetics and Genomics in Personalised Medicine, Sydney, Australia. Conference Contribution - Poster Presentation (not in published proceedings)
Osborne, A. J., Brauning, R., Schultz, J. K., Kennedy, M. A., Slate, J., & Gemmell, N. J. (2012). Development of a predicted physical map of microsatellite locus positions for pinnipeds, with wider applicability to the Carnivora. Proceedings of the Centre for Reproduction and Genomics 4th Annual Research Colloquium. (pp. 13). Retrieved from http://www.otago.ac.nz/crg/news/colloquium/ Conference Contribution - Published proceedings: Abstract
Balasubramanain, D., Hampton, M., & Kennedy, M. (2012, November). Effect of valproate on SPR gene expression in a serotonergic cell line. Verbal presentation at the 8th Annual Carney Pharmacogenomics Symposium, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Chua, E. W., Foulds, J., Miller, A. L., & Kennedy, M. A. (2012, November). Novel CYP2D6 mutation in a patient with poor response to venlafaxine. Verbal presentation at the 8th Annual Carney Pharmacogenomics Symposium, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. A., Chua, E. W., Barclay, M. L., & Savage, R. (2012, November). Growing a New Zealand biobank (UDRUGS) to allow genetic analysis of rare, serious adverse drug reactions and unusual drug responses. Verbal presentation at the 8th Annual Carney Pharmacogenomics Symposium, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. (2012, September). Genomes and drugs: How do we make them work together? Verbal presentation at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Stevens, A., Stuffrein-Roberts, S., Miller, A., Gibb, A., Doudney, K., Bagshaw, A., Aitchison, A., Eccles, M., … Kennedy, M. (2012, August). G-quadruplex DNA structures, genomic imprinting and allelic drop-out in PCR. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Stevens, A. J., Stuffrein-Roberts, S., Miller, A. L., Gibb, A., Doudney, K., Bagshaw, A., Aitchison, A., Eccles, M. R., … Kennedy, M. A. (2012, August). G-quadruplex DNA structures, genomic imprinting and allelic drop-out in PCR. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Chua, E. W., & Kennedy, M. A. (2012). Current state and future prospects of direct-to-consumer pharmacogenetics. Frontiers in Pharmacology, 3, 152. doi: 10.3389/fphar.2012.00152 Journal - Research Article
Kennedy, M. A., Joyce, P. R., & Begg, E. J. (2012). Institutional Profile: The Carney Centre for Pharmacogenomics: A New Zealand focus for personalized medicine research [News & Views]. Pharmacogenomics, 13(8), 865-868. doi: 10.2217/pgs.12.55 Journal - Research Other
Fergusson, D. M., Boden, J. M., Horwood, L. J., Miller, A., & Kennedy, M. A. (2012). Moderating role of the MAOA genotype in antisocial behaviour. British Journal of Psychiatry, 200(2), 116-123. doi: 10.1192/bjp.bp.111.093328 Journal - Research Article
Harley, J. A., Kennedy, M. A., Doudney, K., Allington, M., Pearson, J., Black, M., & Joyce, P. R. (2011). Antidepressants cause specific changes in the rat peripheral blood transcriptome. Biological Psychiatry. 69(9, Suppl. 1), (pp. 89S). [Abstract] Conference Contribution - Published proceedings: Abstract
Fergusson, D. M., Boden, J. M., Horwood, L. J., Miller, A. L., & Kennedy, M. A. (2011). MAOA, abuse exposure and antisocial behaviour: 30-year longitudinal study. British Journal of Psychiatry, 198, 457-463. doi: 10.1192/bjp.bp.110.086991 Journal - Research Article
Osborne, A. J., Brauning, R., Schultz, J. K., Kennedy, M. A., Slate, J., & Gemmell, N. J. (2011). Development of a predicted physical map of microsatellite locus positions for pinnipeds, with wider applicability to the Carnivora. Molecular Ecology Resources, 11(3), 503-513. doi: 10.1111/j.1755-0998.2010.02962.x Journal - Research Article
Kennedy, M. (2011, March). Genomics and sport: Facts and fairytales. Verbal presentation at the Future of Fairness Symposium, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Fergusson, D. M., Horwood, L. J., Miller, A. L., & Kennedy, M. A. (2011). Life stress, 5-HTTLPR and mental disorder: Findings from a 30-year longitudinal study. British Journal of Psychiatry, 198, 129-135. doi: 10.1192/bjp.bp.110.085993 Journal - Research Article
Maggo, S. D. S., Kennedy, M. A., & Clark, D. W. J. (2011). Clinical implications of pharmacogenetic variation on the effects of statins. Drug Safety, 34(1), 1-19. doi: 10.2165/11584380-000000000-00000 Journal - Research Article
McHugh, P. C., Joyce, P. R., Deng, X., & Kennedy, M. A. (2011). A polymorphism of the GTP-cyclohydrolase I feedback regulator gene alters transcriptional activity and may affect response to SSRI antidepressants. Pharmacogenomics Journal, 11(3), 207-213. doi: 10.1038/tpj.2010.23 Journal - Research Article
Marshall, A. J., Negro, S. S., Robertson, B. C., Chilvers, B. L., Kennedy, M. A., & Gemmell, N. J. (2010, September). Can human health research hold the key to New Zealand sea lion survival? Poster session presented at the Fourth Annual Division of Health Sciences Research Forum, Dunedin, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Harley, J. A., Doudney, K., Allington, M. A., McNoe, L., Pearson, J., Black, M., Joyce, P. R., & Kennedy, M. A. (2010). Antidepressant specific changes in rat whole blood gene expression identified by gene-chip analysis. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Annual Scientific Meeting and the 6th Annual Carney Pharmacogenomics Symposium. ASCEPT. Retrieved from http://www.ascept.org.nz/ Conference Contribution - Published proceedings: Abstract
Kennedy, M. (2010). Pharmacogenetics and pain. Proceedings of the Australian and New Zealand College of Anaesthetists (ANZCA) Annual Scientific Meeting. Retrieved from http://www.conference.co.nz/index.cfm/anzca10 Conference Contribution - Published proceedings: Abstract
Kennedy, M. (2010, February). Probing psychiatric drug action by analysis of gene expression. Verbal presentation at the 9th Annual MicroArray Workshop, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Stamp, L. K., Chapman, P. T., O'Donnell, J. L., Zhang, M., James, J., Frampton, C., Barclay, M. L., Kennedy, M. A., & Roberts, R. L. (2010). Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate. Pharmacogenetics & Genomics, 20(6), 367-376. doi: 10.1097/FPC.0b013e3283398a71 Journal - Research Article
Kennedy, M. (2010, March). Novel genetic variants that impact on Thiopurine drug responses. Verbal presentation at the NZBIO Conference: Advancing a bio-based economy, Auckland, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Joyce, P. R., Light, K. J., Rowe, S. L., Cloninger, C. R., & Kennedy, M. A. (2010). Self-mutilation and suicide attempts: Relationships to bipolar disorder, borderline personality disorder, temperament and character. Australian & New Zealand Journal of Psychiatry, 44(3), 250-257. doi: 10.3109/00048670903487159 Journal - Research Article
Glubb, D. M., McHugh, P. C., Deng, X., Joyce, P. R., & Kennedy, M. A. (2010). Association of a functional polymorphism in the adrenomedullin gene (ADM) with response to paroxetine. Pharmacogenomics Journal, 10, 126-133. doi: 10.1038/tpj.2009.33 Journal - Research Article
McHugh, P. C., Rogers, G. R., Glubb, D. M., Joyce, P. R., & Kennedy, M. A. (2010). Proteomic analysis of rat hippocampus exposed to the antidepressant paroxetine. Journal of Psychopharmacology, 24(8), 1243-1251. doi: 10.1177/0269881109102786 Journal - Research Article
Harley, J., Roberts, R., Joyce, P., Mulder, R., Luty, S., Frampton, C., & Kennedy, M. (2010). Orosomucoid influences the response to antidepressants in major depressive disorder. Journal of Psychopharmacology, 24(4), 531-535. doi: 10.1177/0269881109105101 Journal - Research Article
Doudney, K., Harley, J. A., Pearson, J. F., Miller, A., Aitchison, A., Kennedy, M. A., Porter, R. J., Elmslie, J. L., & Joyce, P. R. (2009). Upstream genetic variant near INSIG2 is associated with adipose metabolism in bipolar patients with valproate induced weight gain. Proceedings of the 5th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.otago.ac.nz/christchurch/otago019049.pdf Conference Contribution - Published proceedings: Abstract
Kennedy, M. A., Deng, X. Y., Doudney, K., McHugh, P. C., & Joyce, P. R. (2009). Exploring gene regulation by antidepressant drugs. Proceedings of the American Society of Human Genetics 59th Annual Meeting. (pp. 633). Retrieved from http://www.ashg.org/2009meeting/pdf/poster_4up.pdf Conference Contribution - Published proceedings: Abstract
Doudney, K., Harley, J. A., Deng, X. Y., Allington, M., Waldvogel, H. J., Faull, R. L. M., Joyce, P. R., & Kennedy, M. A. (2009). Brain and peripheral gene expression changes in rats after two weeks of exposure to antidepressant drugs. Proceedings of the American Society of Human Genetics 59th Annual Meeting. (pp. 626). Retrieved from http://www.ashg.org/2009meeting/pdf/poster_4up.pdf Conference Contribution - Published proceedings: Abstract
Bagshaw, A. T., Joyce, P. R., & Kennedy, M. A. (2009). Does copy number variation influence personality? Proceedings of the American Society of Human Genetics 59th Annual Meeting. (pp. 574). Retrieved from http://www.ashg.org/2009meeting/pdf/poster_4up.pdf Conference Contribution - Published proceedings: Abstract
Roberts, R. L., O'Donnell, J. L., Chapman, P. T., Zhang, M., James, J., Frampton, C., Kennedy, M. A., Barclay, M. L., & Stamp, L. K. (2009). Genetic polymorphisms in the folate pathway predict red blood cell folate concentrations but not methotrexate response in rheumatoid arthritis. Proceedings of the 5th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.otago.ac.nz/christchurch/otago019049.pdf Conference Contribution - Published proceedings: Abstract
Harley, J. A., Doudney, K., Allington, M., Pearson, J., Black, M., Joyce, P. R., & Kennedy, M. A. (2009). Blood mRNA changes induced by antidepressants. Proceedings of the 5th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.otago.ac.nz/christchurch/otago019049.pdf Conference Contribution - Published proceedings: Abstract
Deng, S., McHugh, P. C., Doudney, K., Joyce, P. R., & Kennedy, M. A. (2009). Gene regulation by drugs used to treat mood disorders. Proceedings of the 5th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.otago.ac.nz/christchurch/otago019049.pdf Conference Contribution - Published proceedings: Abstract
Johnstone, A. C., Kennedy, M. A., Lea, R. A., & Fitzmaurice, P. S. (2009). The effect of exposure to benzylpiperazine or methamphetamine on gene expression. Proceedings of the 5th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.otago.ac.nz/christchurch/otago019049.pdf Conference Contribution - Published proceedings: Abstract
Stamp, L., O'Donnell, J. L., Chapman, P. T., Zhang, M., Frampton, C., Barclay, M., Kennedy, M., & Roberts, R. (2009). Functional polymorphisms within the folate pathway predict red blood cell folate concentrations but are not associated with methotrexate response in RA. Arthritis & Rheumatism, 60(Suppl. 10), (pp. S150). doi: 10.1002/art.27423 Conference Contribution - Published proceedings: Abstract
Fraser, R., Joyce, P., Sellman, D., & Kennedy, M. (2009). The Body, the Research, the Professor: Mental Health [Episode 4] [Film]. Christchurch, New Zealand: Canterbury Medical Research Foundation. Retrieved from http://www.cmrf.org.nz/Home/Videos/#vid1 Film/Video/CD Rom
Xu, J. B., Mitchell, N. L., Kennedy, M. A., & Palmer, D. N. (2009). Allelic variation in exon1 of CLN5 is not disease associated. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract] Conference Contribution - Published proceedings: Abstract
Harley, J. A., Doudney, K., Allington, M., Pearson, J., Black, M., Joyce, P. R., & Kennedy, M. A. (2009). Blood mRNA changes induced by antidepressants: Future biomarkers to tailor depression treatment? Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract] Conference Contribution - Published proceedings: Abstract
Marshall, A. J., Negro, S. S., Robertson, B. C., Chilvers, B. L., Kennedy, M. A., & Gemmell, N. J. (2009). Assessing genomic variability in species of high conservation priority. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract] Conference Contribution - Published proceedings: Abstract
Doudney, K., Harley, J. A., Deng, X. Y., Allington, M., Waldvogel, H. J., Faull, R. L. M., Joyce, P. R., & Kennedy, M. A. (2009). Gene expression changes in rat brain following antidepressant drug treatment. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract] Conference Contribution - Published proceedings: Abstract
Deng, X., McHugh, P. C., Doudney, K., Joyce, P. R., & Kennedy, M. A. (2009). Gene regulation by drugs used to treat mood disorders. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract] Conference Contribution - Published proceedings: Abstract
Petermann, I., Huebner, C., Browning, B. L., Gearry, R. B., Barclay, M. L., Kennedy, M., Roberts, R., … Han, D. Y., & Ferguson, L. R. (2009). Interactions among genes influencing bacterial recognition increase IBD risk in a population-based New Zealand cohort. Human Immunology, 70, 440-446. doi: 10.1016/j.humimm.2009.03.002 Journal - Research Article
Roberts, R. L., O'Donnell, J. L., Chapman, P. T., Zhang, M., James, J., Frampton, C., Kennedy, M. A., Barclay, M. L., & Stamp, L. K. (2009, September). Genetic polymorphisms in the folate pathway are predictive of red blood cell folate concentrations but not methotrexate response in rheumatoid arthritis patients. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Annual Scientific Meeting, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Johnstone, A., Brennan, K., Schenk, S., Kennedy, M., Fitzmaurice, P., & Lea, R. (2009, September). Neurogenomics of drugs of abuse: Methamphetamine and benzylpiperazine. Poster session presented at the Third Annual Division of Health Sciences Research Forum, Wellington, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Deng, X. S., McHugh, P. C., Doudney, K., Joyce, P. R., & Kennedy, M. A. (2009, September). Gene regulation by drugs used to treat mood disorders. Poster session presented at the Third Annual Division of Health Sciences Research Forum, Wellington, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Doudney, K., Harley, J. A., Pearson, J. F., Miller, A., Aitchison, A., Kennedy, M. A., Porter, R. J., Elmslie, J. L., & Joyce, P. R. (2009). Upstream genetic variant near INSIG2, influences response to carnitine supplementation in bipolar patients with valproate-induced weight gain. Acta Neuropsychiatrica, 21(3), 133-140. doi: 10.1111/j.1601-5215.2009.00379.x Journal - Research Article
Stamp, L. K., O'Donnell, J. L., Chapman, P. T., Barclay, M. L., Kennedy, M. A., Frampton, C. M. A., & Roberts, R. L. (2009). Lack of association between HLA-G 14 bp insertion/deletion polymorphism and response to longterm therapy with methotrexate response in rheumatoid arthritis [Letter]. Annals of the Rheumatic Diseases, 68(1), 154-155. doi: 10.1136/ard.2008.089383 Journal - Research Other
Glubb, D. M., Joyce, P. R., & Kennedy, M. A. (2009). Expression and association analyses of promoter variants of the neurogenic gene HES6, a candidate gene for mood disorder susceptibility and antidepressant response. Neuroscience Letters, 460, 185-190. doi: 10.1016/j.neulet.2009.05.065 Journal - Research Article
McHugh, P. C., Joyce, P. R., & Kennedy, M. A. (2009). Polymorphisms of sepiapterin reductase gene alter promoter activity and may influence risk of bipolar disorder. Pharmacogenetics & Genomics, 19(5), 330-337. doi: 10.1097/FPC.0b013e328328f82c Journal - Research Article
Joyce, P. R., McHugh, P. C., Light, K. J., Rowe, S., Miller, A. L., & Kennedy, M. A. (2009). Relationships between angry-impulsive personality traits and genetic polymorphisms of the dopamine transporter. Biological Psychiatry, 66(8), 717-721. doi: 10.1016/j.biopsych.2009.03.005 Journal - Research Article
Kennedy, M. A., Boden, J. M., Miller, A., Horwood, L. J., & Fergusson, D. M. (2008). Is the CHRNA3-CHRNA5 genomic region really a susceptibility locus for nicotine addiction? Proceedings of the 4th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.chmeds.ac.nz/research/carneycentre/symposium.htm Conference Contribution - Published proceedings: Abstract
Palmer, B. R., Jarvis, M. D., Pilbrow, A. P., Frampton, C. M., Skelton, L., Littlejohn, M. D., Kennedy, M. A., … Yandle, T. G., Richards, A. M., & Cameron, V. A. (2008). Cardiovascular pharmacogenetics: Taking the opportunities. Proceedings of the 4th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.chmeds.ac.nz/research/carneycentre/symposium.htm Conference Contribution - Published proceedings: Abstract
Gearry, R. B., Roberts, R. L., Kennedy, M. A., Zhang, M., & Barclay, M. L. (2008). Thiopurine metabolites, intermediate steps on the way to complete thiopurine pharmacogenetics. Proceedings of the 4th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.chmeds.ac.nz/research/carneycentre/symposium.htm Conference Contribution - Published proceedings: Abstract
Deng, X., McHugh, P. C., Doudney, K., Joyce, P. R., & Kennedy, M. A. (2008). Gene regulation by antidepressant drugs. Proceedings of the 4th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.chmeds.ac.nz/research/carneycentre/symposium.htm Conference Contribution - Published proceedings: Abstract
Glubb, D., Joyce, P., McHugh, P., Deng, S., & Kennedy, M. A. (2008). In vitro expression analysis and association study provide evidence for adrenomedullin involvement in response to the antidepressant paroxetine. Proceedings of the 4th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.chmeds.ac.nz/research/carneycentre/symposium.htm Conference Contribution - Published proceedings: Abstract
Kennedy, M. A., Bland, M. V., Roberts, R. L., McHugh, P. C., Light, K. J., Miller, A. L., & Joyce, P. R. (2008). The GATA2 transcription factor gene: Promotor haplotypes and preliminary association with neuropsychiatric phenotypes. Proceedings of the American Society of Human Genetics 58th Annual Meeting. (pp. 362). ASHG. Retrieved from http://www.ashg.org/2008meeting/pdf/abstractbook1.pdf Conference Contribution - Published proceedings: Abstract
Harley, J. A., Doudney, K., Joyce, P. R., & Kennedy, M. A. (2008). Search for the black bile: Biomarkers of antidepressant exposure. Proceedings of the 8th Annual Australasian Microarray and Associated Technologies (AMATA) Conference. Retrieved from http://www.amata.org.au/index.php/resources/2008-conference-abstracts Conference Contribution - Published proceedings: Abstract
Clark, D. W. J., Ashton, J. A., Zhou, L., Wallace, A. K., & Kennedy, M. A. (2008). Pharmacogenetic investigation using a pharmacovigilance database. PharmacoVigilance Review, 2(3), 9-13. Journal - Research Article
Gearry, R. B., Roberts, R. L., Kennedy, M. A., Zhang, M., & Barclay, M. L. (2008, October). Thiopurine metabolites, intermediate steps on the way to complete thiopurine pharmacogenetics. Verbal presentation at the 4th Annual Carney Pharmacogenomics Symposium, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Stuffrein-Roberts, S., Joyce, P. R., & Kennedy, M. A. (2008). Role of epigenetics in mental disorders. Australian & New Zealand Journal of Psychiatry, 42(2), 97-107. Journal - Research Article
Porter, R. J., Mulder, R. T., Joyce, P. R., Miller, A. L., & Kennedy, M. (2008). Tryptophan hydroxylase gene (TPH1) and peripheral tryptophan levels in depression. Journal of Affective Disorders, 109(1-2), 209-212. doi: 10.1016/j.jad.2007.11.010 Journal - Research Article
Roberts, R. L., Gearry, R. B., Bland, M. V., Sies, C. W., George, P. M., Burt, M., … Barclay, M. L., & Kennedy, M. A. (2008). Trinucleotide repeat variants in the promoter of the thiopurine S-methyltransferase gene of patients exhibiting ultra-high enzyme activity. Pharmacogenetics & Genomics, 18(5), 434-438. Journal - Research Article
McHugh, P. C., Rogers, G. R., Loudon, B., Glubb, D. M., Joyce, P. R., & Kennedy, M. A. (2008). Proteomic analysis of embryonic stem cell-derived neural cells exposed to the antidepressant paroxetine. Journal of Neuroscience Research, 86(2), 306-316. Journal - Research Article
Bentley, R. W., Keenan, J. I., Gearry, R. B., Kennedy, M. A., Barclay, M. L., & Roberts, R. L. (2008). Incidence of Mycobacterium avium subspecies paratuberculosis in a population-based cohort of patients with Crohn's disease and control subjects. American Journal of Gastroenterology, 103(5), 1168-1172. doi: 10.1111/j.1572-0241.2007.01742.x Journal - Research Article
McHugh, P. C., Rogers, G. R., Glubb, D. M., Allington, M. D., Hughes, M., Joyce, P. R., & Kennedy, M. A. (2008). Downregulation of Ccnd1 and Hes6 in rat hippocampus after chronic exposure to the antidepressant paroxetine. Acta Neuropsychiatrica, 20(6), 307-313. doi: 10.1111/j.1601-5215.2008.00334.x Journal - Research Article
Lea, R. A., Roberts, R. L., Green, M. R., Kennedy, M. A., & Chambers, G. K. (2008). Allele frequency differences of cytochrome P450 polymorphisms in a sample of New Zealand Māori. New Zealand Medical Journal, 121(1272). Retrieved from http://journal.nzma.org.nz/journal/121-1272/3002/content.pdf Journal - Research Article
Littlejohn, M. D., Palmer, B. R., Richards, A. M., Frampton, C. M., Pilbrow, A. P., Troughton, R. W., Cameron, V. A., & Kennedy, M. A. (2008). Ile164 variant of β2-adrenoceptor does not influence outcome in heart failure but may interact with β blocker treatment. European Journal of Heart Failure, 10(1), 55-59. doi: 10.1016/j.ejheart.2007.10.011 Journal - Research Article
Roberts, R. L., Gearry, R. B., Kennedy, M. A., & Barclay, M. L. (2008). Beyond TPMT: Genetic influences on thiopurine drug responses in inflammatory bowel disease. Personalized Medicine, 5(3), 233-248. doi: 10.2217/17410541.5.3.233 Journal - Research Article
Roberts, R. L., Hollis-Moffatt, J. E., Gearry, R. B., Kennedy, M. A., Barclay, M. L., & Merriman, T. R. (2008). Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population-based cohort. Genes & Immunity, 9(6), 561-565. doi: 10.1038/gene.2008.49 Journal - Research Article
Kennedy, M. A. (2007, December). Pharmacogenetics in the era of personal genomes. Festschrift in honour of Associate Professor David Clark: An international symposium on New Zealand's crucial role in monitoring/improving the safety of Medicine. Dunedin, New Zealand. [Public Seminar]. Other Research Output
Barclay, M., Roberts, R., Gearry, R., & Kennedy, M. (2007). Inflammatory bowel disease pharmacogenetics. Proceedings of the 3rd Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.chmeds.ac.nz/research/carneycentre/symposium.htm Conference Contribution - Published proceedings: Abstract
Harley, J. A., Joyce, P. R., & Kennedy, M. A. (2007). The search for the black bile: Peripheral biomarkers in depression. Proceedings of the 3rd Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.chmeds.ac.nz/research/carneycentre/symposium.htm Conference Contribution - Published proceedings: Abstract
Glubb, D., Rogers, G., Joyce, P. R., & Kennedy, M. A. (2007). Antidepressant pharmacogenomics of a serotonergic cell line. Proceedings of the 3rd Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.chmeds.ac.nz/research/carneycentre/symposium.htm Conference Contribution - Published proceedings: Abstract
McHugh, P. C., Joyce, P. R., & Kennedy, M. A. (2007). Sepiapterin reductase (SPR): A novel candidate gene for antidepressant response and affective disorders? Proceedings of the 3rd Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.chmeds.ac.nz/research/carneycentre/symposium.htm Conference Contribution - Published proceedings: Abstract
Roberts, R. L., Gearry, R. B., Bland, M. V., Sies, C., George, P. M., Burt, M., Kennedy, M. A., & Barclay, M. L. (2007). Trinucleotide repeat variants in inflammatory bowel disease patients exhibiting ultra-high thiopurine S-methyltransferase activity. Proceedings of the 3rd Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.chmeds.ac.nz/research/carneycentre/symposium.htm Conference Contribution - Published proceedings: Abstract
Joyce, P., Light, K., Rowe, S., & Kennedy, M. (2007). Self mutilation and suicide attempts, temperament and character, in borderline personality disorder and bipolar disorder. Proceedings of the Australasian Society for Bipolar Disorders Conference. Retrieved from http://www.asbd2007.com/ Conference Contribution - Published proceedings: Abstract
Joyce, P., Light, K., Rowe, S., & Kennedy, M. (2007). Bipolar disorder NOS: A comparison with bipolar disorder I/II and major depression. Proceedings of the Australasian Society for Bipolar Disorders Conference. Retrieved from http://www.asbd2007.com/ Conference Contribution - Published proceedings: Abstract
Roberts, R. L., Gearry, R. B., Hollis-Moffatt, J. E., Miller, A. L., Reid, J., Abkevich, V., … Merriman, T. R., Barclay, M. L., & Kennedy, M. A. (2007). IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease. New Zealand Medical Journal, 120(1266). Retrieved from http://journal.nzma.org.nz/journal/120-1266/2848/content.pdf Conference Contribution - Published proceedings: Abstract
Roberts, R. L., Gearry, R. B., Barclay, M. L., & Kennedy, M. A. (2007). Method of identifying individuals at risk of thiopurine drug resistance and intolerance. International (PCT) Patent Application (PCT/NZ2007/000329). Intellectual Property
Roberts, R. L., Gearry, R. B., Barclay, M. L., & Kennedy, M. A. (2007). Method of identifying individuals at risk of thiopurine drug resistance and intolerance. United States Patent Application (60/935367). Intellectual Property
Bentley, R. W., Roberts, R. L., Gearry, R. B., Keenan, J. I., Kennedy, M. A., & Barclay, M. L. (2007, November). Relative incidence of Mycobacterium avium subsp. paratuberculosis in a New Zealand population-based cohort of patients with Crohn's disease. Verbal presentation at the New Zealand Society of Gastroenterology & NZNO Gastroenterology Nurses Section Annual Scientific Meeting combined with the RACP and IMSANZ, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Stamp, L. K., O'Donnell, J. L., Chapman, P. T., Frampton, C., Barclay, M. L., Kennedy, M., & Roberts, R. L. (2007, August-September). HLA-G 14BP polymorphism is not associated with response to methotrexate in rheumatoid arthritis. Verbal presentation at the New Zealand Rheumatology Association Conference, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Barclay, M. L., Roberts, R. L., Gearry, R. B., Zhang, M., & Kennedy, M. A. (2007, August). Novel gene mutations for enzymes in the thiopurine metabolic pathway in patients with inflammatory bowel disease and severe azathioprine resistance. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists & Toxicologists (NZ) Annual Scientific Meeting, Auckland, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Roberts, R. L., Gearry, R. B., Bland, M. V., Sies, C. W., George, P. M., Burt, M., Kennedy, M. A., & Barclay, M. L. (2007, October). Promoter insertion in an inflammatory bowel disease patient exhibiting ultra-high thiopurine S-methyltransferase activity. Verbal presentation at the Joint Cold Spring Harbor Laboratory/Wellcome Trust Conference, Cold Spring Harbor, New York. Conference Contribution - Verbal presentation and other Conference outputs
Barclay, M., Roberts, R., Gearry, R., & Kennedy, M. (2007, September). Inflammatory bowel disease pharmacogenetics. Verbal presentation at the 3rd Annual Carney Pharmacogenomics Symposium, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Bentley, R. W., Gearry, R. B., Keenan, J. I., Aitken, J. M., Kennedy, M. A., Barclay, M. L., & Roberts, R. L. (2007). Relative incidence of Mycobacterium avium subsp. paratuberculosis in a population-based cohort of Crohn's disease patients. Gut. 56(Suppl. III), (pp. A127). [Abstract] Conference Contribution - Published proceedings: Abstract
Roberts, R. L., Gearry, R. B., Hollis-Moffatt, J. E., Miller, A. L., Reid, J., Abkevich, V., … Merriman, T. R., Barclay, M. L., & Kennedy, M. A. (2007). IL23R R381Q & ATG16L1 T300A are associated with Crohn's disease in a population-based New Zealand Caucasian cohort. Gut. 56(Suppl. III), (pp. A19). [Abstract] Conference Contribution - Published proceedings: Abstract
Roberts, R. L., Gearry, R. B., Hollis-Moffatt, J. E., Miller, A. L., Reid, J., Abkevich, V., … Merriman, T. R., Barclay, M. L., & Kennedy, M. A. (2007, November). IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease. Verbal presentation at the New Zealand Society of Gastroenterology & NZNO Gastroenterology Nurses Section Annual Scientific Meeting combined with the RACP and IMSANZ, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Roberts, R. L., Gearry, R. B., Bland, M. V., Sies, C. W., George, P. M., Burt, M., Kennedy, M. A., & Barclay, M. L. (2007, September). Trinucleotide repeat variants in inflammatory bowel disease patients exhibiting ultra-high thiopurine S-methyltransferase activity. Verbal presentation at the 3rd Annual Carney Pharmacogenomics Symposium, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Bentley, R. W., Roberts, R. L., Gearry, R. B., Merriman, T. R., Kennedy, M. A., & Barclay, M. L. (2007). The GLI1 gene as a risk factor for ulcerative colitis GLI1. Proceedings of the American Society of Human Genetics 57th Annual Meeting. Retrieved from http://www.ashg.org/genetics/ashg/annmeet/2007/call/postersessionlisting.shtml Conference Contribution - Published proceedings: Abstract
Bentley, R. W., Roberts, R. L., Gearry, R. B., Merriman, T. R., Kennedy, M. A., & Barclay, M. L. (2007). The GLI1 gene as a risk factor for ulcerative colitis. Journal of Gastroenterology & Hepatology, 22(Suppl. 3), (pp. A321). doi: 10.1111/j.1440-1746.2007.05172.x Conference Contribution - Published proceedings: Abstract
Bentley, R. W., Gearry, R. B., Keenan, J. I., Aitken, J. M., Kennedy, M. A., Barclay, M. L., & Roberts, R. L. (2007). Relative incidence of Mycobacterium avium subsp. paratuberculosis in a population-based cohort of Crohn's disease patients. Journal of Gastroenterology and Hepatology. 22(Suppl. 3), (pp. A317). [Abstract] Conference Contribution - Published proceedings: Abstract
Roberts, R. L., Gearry, R. B., Hollis-Moffatt, J. E., Miller, A. L., Reid, J., Abkevich, V., … Merriman, T. R., Barclay, M. L., & Kennedy, M. A. (2007). IL23R R381Q & ATG16L1 T300A are associated with Crohn's disease in a population-based Caucasian cohort. Journal of Gastroenterology & Hepatology, 22(Suppl. 3), (pp. A305). doi: 10.1111/j.1440-1746.2007.05172.x Conference Contribution - Published proceedings: Abstract
Gearry, R., Nolan, R., Roberts, R., Barclay, M., Kennedy, M. A., Patterson, A., … Nolan, D. (2007). HLA, TPMT and ITPA genotypes and susceptibility to azathioprine hypersensitivity reactions (HSR) in inflammatory bowel disease (IBD) patients. Journal of Gastroenterology & Hepatology, 22(Suppl. 3), (pp. A304). doi: 10.1111/j.1440-1746.2007.05172.x Conference Contribution - Published proceedings: Abstract
Beaglehole, B., Luty, S. E., Mulder, R. T., Kennedy, M. A., & Joyce, P. R. (2007). Low red cell folate levels are associated with poor response to nortriptyline in major depression. Acta Neuropsychiatrica, 19, 204-207. Journal - Research Article
Johnstone, A. C., Lea, R. A., Brennan, K. A., Schenk, S., Kennedy, M. A., & Fitzmaurice, P. S. (2007). Benzylpiperazine: A drug of abuse? [Review]. Journal of Psychopharmacology, 21, 888-894. doi: 10.1177/0269881107077260 Journal - Research Article
Kennedy, M. A. (2007). Pharmacogenomics: Single genes, whole genomes and global networks [Conference scene]. Personalized Medicine, 4(1), 87-94. Journal - Research Other
Light, K. J., Miller, A. L., Doughty, C. J., Joyce, P. R., Olds, R. J., & Kennedy, M. A. (2007). FAT and bipolar affective disorder [Letter to the editor]. Molecular Psychiatry, 12, 899-900. Journal - Research Other
Joyce, P. R., Light, K. J., Rowe, S. L., & Kennedy, M. A. (2007). Bipolar disorder not otherwise specified: Comparison with bipolar disorder I/II and major depression. Australian & New Zealand Journal of Psychiatry, 41, 843-849. Journal - Research Article
Roberts, R. L., Gearry, R. B., Hollis-Moffatt, J. E., Miller, A. L., Reid, J., Abkevich, V., … Merriman, T. R., Barclay, M. L., & Kennedy, M. A. (2007). IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease. American Journal of Gastroenterology, 102, 2754-2761. Journal - Research Article
Roberts, R. L., Gearry, R. B., Barclay, M. L., & Kennedy, M. A. (2007). IMPDH1 promoter mutations in a patient exhibiting azathioprine resistance. Pharmacogenomics Journal, 7(5), 312-317. Journal - Research Article
Light, K. J., Joyce, P. R., Luty, S. E., Mulder, R. T., Carter, J. D., Frampton, C. M. A., Miller, A. L., & Kennedy, M. A. (2007). An association study of DRD2 and COMT polymorphisms with novelty seeking and harm avoidance scores, in two independent samples of depressed patients. Behavioral & Brain Functions, 3(3). Retrieved from http://www.behavioralandbrainfunctions.com/content/3/1/3 Journal - Research Article
Gearry, R. B., Roberts, R. L., Burt, M. J., Frampton, C. M. A., Chapman, B. A., Collett, J. A., Shirley, P., Allington, M. D. E., Kennedy, M. A., & Barclay, M. L. (2007). Effect of inflammatory bowel disease classification changes on NOD2 genotype-phenotype associations in a population-based cohort. Inflammatory Bowel Diseases, 13(10), 1220-1227. Journal - Research Article
Bland, M., Joyce, P., & Kennedy, M. (2006). Genetic variation of 5-HT transcription factors in affective disorders. Proceedings of the 11th International Congress of Human Genetics. Retrieved from http://www.ichg2006.com/abstract/777.htm Conference Contribution - Published proceedings: Abstract
Gearry, R. B., Roberts, R. R., Richardson, A., Frampton, C. M. A., Kennedy, M. A., & Barclay, M. L. (2006). The prevalence and genetic determinants of inflammatory bowel disease (IBD) in Canterbury. New Zealand Medical Journal, 119(1231). Retrieved from http://journal.nzma.org.nz/journal/119-1231/1922/content.pdf Conference Contribution - Published proceedings: Abstract
Kennedy, M. A., McHugh, P. C., Rogers, G. R., Glubb, D. M., Allington, M., & Joyce, P. R. (2006). Gene and protein expression changes induced by chronic exposure to the antidepressant paroxetine. New Zealand Medical Journal, 119(1231). Retrieved from http://journal.nzma.org.nz/journal/119-1231/1922/content.pdf Conference Contribution - Published proceedings: Abstract
Kennedy, M. A., Roberts, R. R., Gearry, R. B., Barclay, M. L., Taylor, D. R., Begg, E. J., Clark, D. W. J., & Joyce, P. R. (2006). Pharmacogenetics and genomics ″Down Under″: Focus on asthma, inflammatory bowel disease, and major depression. Proceedings of the Pharmacogenomics Meeting. (pp. 11). NY: Cold Spring Harbor Laboratory. [Abstract] Conference Contribution - Published proceedings: Abstract
Gearry, R. B., Roberts, R. L., Frampton, C. M., Burt, M. J., Collett, J. A., Chapman, B. A., Allington, M. D., Kennedy, M. A., & Barclay, M. L. (2006). From Vienna to Montreal: The impact of changes in IBD classification on CARD15 genotype-phenotype relationships in a population-based cohort. Gastroenterology. 130(4, Suppl. 2), (pp. A-586). [Abstract] Conference Contribution - Published proceedings: Abstract
Gearry, R. B., Roberts, R. L., Frampton, C. M., Burt, M. J., Collett, J. A., Chapman, B. A., Allington, M. D., Kennedy, M. A., & Barclay, M. L. (2006). From Vienna to Montreal: The impact of changes in IBD classification on CARD15 genotype-phenotype relationships in a population-based cohort. Journal of Gastroenterology & Hepatology, 21(Suppl. 4), (pp. A271). doi: 10.1111/j.1440-1746.2006.04687.x Conference Contribution - Published proceedings: Abstract
Roberts, R. L., Gearry, R. B., Kennedy, M. A., & Barclay, M. L. (2006, November-December). Mutations in the guanosine 5'-monophosphate synthetase (GMPS) gene are associated with thiopurine resistance. Poster session presented at the Medical Sciences Congress, Rotorua, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Stamp, L., Roberts, R., Kennedy, M., Barclay, M., O'Donnell, J., & Chapman, P. (2006). The use of low dose methotrexate in rheumatoid arthritis: Are we entering a new era of therapeutic drug monitoring and pharmacogenomics? Biomedicine & Pharmacotherapy, 60, 678-687. Journal - Research Other
Joyce, P. R., McKenzie, J. M., Mulder, R. T., Luty, S. E., Sullivan, P. F., Miller, A. L., & Kennedy, M. A. (2006). Genetic, developmental and personality correlates of self-mutilation in depressed patients. Australian & New Zealand Journal of Psychiatry, 40, 225-229. Journal - Research Article
Light, K. J., Joyce, P. R., Luty, S. E., Mulder, R. T., Frampton, C. M. A., Joyce, L. R. M., Miller, A. L., & Kennedy, M. A. (2006). Preliminary evidence for an association between a dopamine D3 receptor gene variant and obsessive-compulsive personality disorder in patients with major depression. American Journal of Medical Genetics Part B, 141B(4), 409-413. doi: 10.1002/ajmg.b.30308 Journal - Research Article
Gearry, R. B., Lea, R. A., Roberts, R. L., Chambers, G. K., Barclay, M. L., & Kennedy, M. A. (2006). CARD15 allele frequency differences in New Zealand Maori: Ancestry specific susceptibility to Crohn's disease in New Zealand? [Letter]. Gut, 55, 580. doi: 10.1136/gut.2005.085464 Journal - Research Other
Fitches, A., Clark, D., Joyce, P. R., Kennedy, M. A., Wells, J. E., & Olds, R. J. (2006). Association of alleles at GSK3b-50 with bipolar disorder age of onset. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. (7), 141B, (pp. 746). [Abstract] Conference Contribution - Published proceedings: Abstract
Joyce, P. R., McHugh, P. C., McKenzie, J. M., Sullivan, P. F., Mulder, R. T., Luty, S. E., Carter, J. D., Frampton, C. M. A., … Miller, A. L., & Kennedy, M. A. (2006). A dopamine transporter polymorphism is a risk factor for borderline personality disorder in depressed patients. Psychological Medicine, 36, 807-813. doi: 10.1017/s0033291706007288 Journal - Research Article
Roberts, R. L., & Kennedy, M. A. (2006). Rapid detection of common cytochrome P450 2D6 alleles in Caucasians. Clinica Chimica Acta, 366, 348-351. Journal - Research Article
Glubb, D. M., McHugh, P. C., Rogers, G. R., Joyce, P. R., & Kennedy, M. A. (2005, August). Molecular approaches for understanding antidepressant function. Poster session presented at the 23rd International Australasian Winter Conference on Brain Research, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Kennedy, M. A., McHugh, P. C., Glubb, D. M., Rogers, G. R., & Joyce, P. R. (2005, October). Molecular changes induced by chronic exposure to the antidepressant paroxetine in a neuronal cell culture system. Poster session presented at the American Society of Human Genetics 55th Annual Meeting, Salt Lake City, UT, USA. Conference Contribution - Poster Presentation (not in published proceedings)
Bland, M. V., Joyce, P. R., McHugh, P. C., & Kennedy, M. A. (2005, August). Polymorphism analysis of novel serotonergic candidate genes in depression. Poster session presented at the 15th Annual Queenstown Molecular Biology Meeting, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Glubb, D., McHugh, P., Rogers, G., Allington, M., Cameron, V., Joyce, P., & Kennedy, M. (2005, August). Validating gene expression changes caused by exposure of neuron cultures and rat brain to the antidepressant paroxetine (Aropax). Poster session presented at the 15th Annual Queenstown Molecular Biology Meeting, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Bland, M. V., Joyce, P. R., McHugh, P. C., & Kennedy, M. A. (2005, August). Polymorphism analysis of novel serotonergic candidate genes in depression. Poster session presented at the 23rd International Australasian Winter Conference on Brain Research, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Roberts, R. L., Gearry, R. B., Barclay, M. L., & Kennedy, M. A. (2005). Interim CARD15 genotype results from a population-based study of Inflammatory Bowel Disease. European Journal of Human Genetics, 13(Suppl. 1), (pp. 304). [Abstract] Conference Contribution - Published proceedings: Abstract
Gearry, R., Roberts, R., Richardson, A., Frampton, C., Kennedy, M., & Barclay, M. (2005, November). The epidemiology and genetic determinants of inflammatory bowel disease (IBD) in Canterbury. Verbal presentation at the New Zealand Society of Gastroenterology & NZNO Gastroenterology Nurses Section Annual Scientific Meeting, Hamilton, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Barclay, M. L., Roberts, R. L., Gearry, R. B., & Kennedy, M. A. (2005, September). Interim CARD15 genotype results from a population-based study of inflammatory bowel disease in New Zealand. Poster session presented at the World Congress of Gastroenterology, Montréal, Canada. Conference Contribution - Poster Presentation (not in published proceedings)
Taylor, D. R., Epton, M. J., Kennedy, M. A., Smith, A. D., Iles, S., Miller, A. L., Littlejohn, M. D., Cowan, J. O., Hewitt, T., Swanney, M. P., Brassett, K. P., & Herbison, G. P. (2005). Bronchodilator response in relation to β2-adrenoceptor haplotype in patients with asthma. American Journal of Respiratory & Critical Care Medicine, 172(6), 700-703. Journal - Research Article
Joyce, P. R., Porter, R. J., Mulder, R. T., Luty, S. E., McKenzie, J. M., Miller, A. L., & Kennedy, M. A. (2005). Reversed diurnal variation in depression: Associations with a differential antidepressant response, tryptophan: Large neutral amino acid ratio and serotonin transporter polymorphisms. Psychological Medicine, 35, 511-517. Journal - Research Article
Roberts, R. L., Potter, H., Harraway, J., Pike, L., George, P. M., & Kennedy, M. A. (2004, April). Characterisation of a length polymorphism in intron 5 of the thiopurine S-methyltransferase (TPMT) gene. Poster session presented at the Human Genome Meeting, Berlin. Conference Contribution - Poster Presentation (not in published proceedings)
Gearry, R. B., Roberts, R. L., Barclay, M. L., & Kennedy, M. A. (2004). Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine. Pharmacogenetics, 14(11), 779-781. Journal - Research Article
Roberts, R. L., Gearry, R. B., Barclay, M. L., & Kennedy, M. A. (2004). Rapid detection of common CARD15 variants in patients with inflammatory bowel disease. Molecular Diagnosis, 8(2), 101-105. doi: 10.1007/BF03260052 Journal - Research Article
Roberts, R. L., Barclay, M. L., Gearry, R. B., & Kennedy, M. A. (2004). A multiplexed allele-specific polymerase chain reaction assay for the detection of common thiopurine S-methyltransferase (TPMT) mutations. Clinica Chimica Acta, 341(1-2), 49-53. Journal - Research Article
Roberts, R. L., Luty, S. E., Mulder, R. T., Joyce, P. R., & Kennedy, M. A. (2004). Association between cytochrome P450 2D6 genotype and harm avoidance. American Journal of Medical Genetics Part B, 127B, 90-93. Wiley-Liss Inc. Journal - Research Article
Kennedy, M. A., Rogers, G. R., & Joyce, P. R. (2004). Pharmacogenetics of antidepressants and mood stabilisers. In P. R. Joyce & P. B. Mitchell (Eds.), Mood disorders: Recognition and treatment. (pp. 223-237). Sydney, Australia: The University of New South Wales Press Ltd. Chapter in Book - Research
Roberts, R. L., Mulder, R. T., Joyce, P. R., Luty, S. E., & Kennedy, M. A. (2004). No evidence of increased adverse drug reactions in cytochrome P450 CYP2D6 poor metabolizers treated with fluoxetine or nortriptyline. Human Psychopharmacology, 19(1), 17-23. Journal - Research Article
Clark, D. W. J., & Kennedy, M. A. (2004). Potential for linking pharmacogenetic investigations with pharmacovigilance databases. Proceedings of the Winter Conference on Pharmacogenomics. (pp. 40). New York: Cold Spring Harbor Laboratory. [Abstract] Conference Contribution - Published proceedings: Abstract
Clark, D. W. J., Donnelly, E., Coulter, D. M., Roberts, R. L., & Kennedy, M. A. (2004). Linking pharmacovigilance with pharmacogenetics. Drug Safety, 27(15), 1171-1184. Journal - Research Article
Rogers, G., Joyce, P., Mulder, R., Sellman, D., Miller, A., Allington, M., Olds, R., Wells, E., & Kennedy, M. (2004). Association of a duplicated repeat polymorphism in the 5′-untranslated region of the DRD4 gene with novelty seeking. American Journal of Medical Genetics Part B, 126B, 95-98. Journal - Research Article
McHugh, P., Rogers, G. R., Allington, M., Cameron, V. A., Begg, E. J., Joyce, P. R., & Kennedy, M. A. (2003, July). Model systems for exploring antidepressant pharmacogenomics. Poster session presented at the XIX International Congress of Genetics: Genomes, the linkage to life, Victoria, Australia. Conference Contribution - Poster Presentation (not in published proceedings)
Clark, D. W., Coulter, D. M., & Kennedy, M. A. (2003). Development of pharmacogenetic investigations in the New Zealand Intensive Medicines Monitoring Programme (IMMP). Pharmacoepidemiology and Drug Safety. 12(Suppl. 2), (pp. S215-S216). [Abstract] Conference Contribution - Published proceedings: Abstract
Sundram, S., Joyce, P. R., & Kennedy, M. A. (2003). Schizophrenia and bipolar affective disorder: Perspectives for the development of therapeutics. Current Molecular Medicine, 3, 393-407. Journal - Research Article
Joyce, P. R., Mulder, R. T., Luty, S. E., McKenzie, J. M., Miller, A., Rogers, G. R., & Kennedy, M. A. (2003). Age-dependent antidepressant pharmacogenomics: Polymorphisms of the serotonin transporter and G protein β3 subunit as predictors of response to fluoxetine and nortriptyline. International Journal of Neuropsychopharmacology, 6, 339-346. Journal - Research Article
Barclay, M. L., Sawyers, S. M., Begg, E. J., Zhang, M., Roberts, R., Kennedy, M. A., & Elliott, J. M. (2003). Correlation of CYP2D6 genotype with perhexiline phenotypic metabolizer status. Pharmacogenetics, 13(10), 627-632. Journal - Research Article
Gearry, R. B., Barclay, M. L., Burt, M. J., Collett, J. A., Chapman, B. A., Roberts, R., & Kennedy, M. A. (2003). Thiopurine S-methyltransferase (TPMT) genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease. Alimentary Pharmacology & Therapeutics, 18, 395-400. Journal - Research Article
Joyce, P. R., Rogers, G. R., Miller, A., Mulder, R. T., Luty, S. E., & Kennedy, M. A. (2003). Polymorphisms of DRD4 and DRD3 and risk of avoidant and obsessive personality traits and disorders. Psychiatry Research, 119, 1-10. Journal - Research Article
Robertson, R. L., Joyce, P. R., Mulder, R. T., Begg, E. J., & Kennedy, M. A. (2002). P-Glycoprotein polymorphisms and nortriptyline-induced hypotension. Proceedings of the ASCEPT Annual Meeting. [Abstract] Conference Contribution - Published proceedings: Abstract
Kennedy, M. A. (2002, August). Drugd and DNA: An ABC of pharmacogenetics [Invited]. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. A. (2002, September). Genetic engineering in medicine: The first 30 years [Invited]. Verbal presentation at the National Conference of the New Zealand Dietetic Association, Palmerston North, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Barclay, M. L., Gearry, R. B., Burt, M. J., Collett, J. A., Roberts, R. L., & Kennedy, M. A. (2002, November). Azathioprine and 6-mercaptopurine adverse effects and TPMT genotype in patients with inflammatory bowel disease. Verbal presentation at the Annual Meeting of the New Zealand Society of Gastroenterology, Auckland, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
McHugh, P., Rogers, G., Allington, M., Cameron, A. V., Edgar, P., Begg, E. J., Joyce, P. R., & Kennedy, M. A. (2002, October). Pharmacogenomics of antidepressant drug responses. Verbal presentation at the Pharmacogenomics: The promise and reality of individualized treatment, Paris, France. Conference Contribution - Verbal presentation and other Conference outputs
Barclay, M. L., Gearry, R. B., Burt, M. J., Collett, J. A., Roberts, R. L., & Kennedy, M. A. (2002, August). Azathioprine and 6-mercaptopurine adverse effects and TPMT genotype in patients with inflammatory bowel disease. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) Meeting, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. A. (2002, November). Coping with compliance [Invited]. Verbal presentation at the Microbes and Molecules Conference, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
McHugh, P., Rogers, G., Allington, M., Cameron, A. V., Edgar, P., Begg, E. J., Joyce, P. R., & Kennedy, M. A. (2002). Pharmacogenomics of antidepressant drug responses. American Journal of Medical Genetics abstracts for the Xth World Congress of Psychiatric Genetics. 114(7), (pp. 881). Brussels, Belgium. [Abstract] Conference Contribution - Published proceedings: Abstract
Allington, M., Rogers, G. R., McHugh, P. C., Cameron, V. A., Edgar, P., Begg, E. J., Joyce, P. R., & Kennedy, M. A. (2002). Exploring differential gene expression in the brain following chronic antidepressant treatment. Proceedings of the 12th Annual Queenstown Molecular Biology Meeting. (pp. T2). Queenstown: Queenstown Molecular Biology Meeting, Inc. [Abstract] Conference Contribution - Published proceedings: Abstract
Stedman, C. A. M., Begg, E. J., Kennedy, M. A., Roberts, R., & Wilkinson, T. J. (2002). Cytochrome P450 2D6 genotype does not predict SSRI (fluoxetine or paroxetine) induced hyponatraemia. Human Psychopharmacology, 17(4), 187-190. Journal - Research Article
Ferguson, G., Heinemann, J., & Kennedy, M. A. (2002). Gene transfer between Salmonella enterica Serovar Typhimuirium inside epithelial cells. Journal of Bacteriology, 184, 2235-2242. Journal - Research Article
Roberts, R. L., Joyce, P. R., Mulder, R. T., Begg, E. J., & Kennedy, M. A. (2002). A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression. Pharmacogenomics Journal, 2(3), 191-196. doi: 10.1038/sj.tpj.6500099 Journal - Research Article
Wood, J. G., Joyce, P. R., Miller, A., Mulder, R. T., & Kennedy, M. A. (2002). A polymorphism in the dopamine β-hydroxylase gene is associated with "paranoid ideation" in patients with major depression. Biological Psychiatry, 51, 365-369. Journal - Research Article
Kennedy, M. A., & Taylor, D. R. (2002). Beta-adrenergic receptor polymorphisms and drug responses in asthmatics. Pharmacogenomics, 3, 173-184. Journal - Research Article
Roberts, R., Begg, E. J., Joyce, P. R., & Kennedy, M. A. (2002). How the pharmacogenetics of cytochrome P450 enzymes may affect prescribing. New Zealand Medical Journal, 115(1150), 137-140. Journal - Research Article
Littlejohn, M. D., Taylor, D. R., Miller, A. L., & Kennedy, M. A. (2002). Determination of β2-adrenergic receptor (ADRB2) haplotypes by a multiplexed polymerase chain reaction assay. Human Mutation, 20(6), 479. doi: 10.1002/humu.9091 Journal - Research Article
Barclay, M. L., Sawyers, S. M., Begg, E. J., Roberts, R. L., Kennedy, M. A., & Elliott, J. M. (2001). Correlation of CYP450 2D6 genotype withperhexiline phenotypic metaboliser status. Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists. 9, (pp. 111). [Full Paper] Conference Contribution - Published proceedings: Full paper
Littlejohn, M. D., Miller, A., Taylor, R., & Kennedy, M. A. (2001). Rapid determination of 2-adrenergic receptor haplotypes using a multiplex polymerase chain reaction. Verbal presentation at the 11th Annual Queenstown Molecular Biology Meeting, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Hopkins, R., & Kennedy, M. A. (2001, August). Variation within the promoter of the murine serotonin transporter gene. Verbal presentation at the 11th Annual Queenstown Molecular Biology Meeting, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. A. (2001, October). A common P-glycoprotein polymorphism is associated with nortriptyline induced postural hypotension in patients treated for major depression. Verbal presentation at the 9th World Congress on Psychiatric Genetics, St Louis, USA. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. A., & Taylor, D. R. (2001). Pharmacogenetics of asthma: Role of the andrenoceptor. Verbal presentation at the Annual Scientific Meeting of the Thoracic Society of Australia and New Zealand, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Taylor, D. R. R., & Kennedy, M. A. (2001). Genetic variation of the β2-adrenoceptor: functional and clinical importance in bronchial asthma. American Journal of PharmacoGenomics, 1(3), 165-174. Journal - Research Article
Kennedy, M. A. (2001). What does the human genome project mean for medicine? New Zealand Medical Journal, 114, 190-192. Journal - Research Article
Martin, J. H., Begg, E. J., Kennedy, M. A., Roberts, R., & Barclay, M. L. (2001). Is cytochrome P450 2C9 genotype associated with NSAID gastric ulceration? British Journal of Clinical Pharmacology, 51, 627-630. Journal - Research Article
Rogers, G., Allington, M., McHugh, P., Cameron, V., Edgar, P., Begg, E., Joyce, P., & Kennedy, M. (2000, July). Exploring differential gene expression in the brain following chronic antidepressant treatment. Verbal presentation at the Australian Microarray Meeting Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. A. (2000, July). Pharmacogenetics: What? How? Why? [Invited speaker]. Verbal presentation at the New Zealand Biotechnology Association Annual Meeting, Auckland. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. A. (2000, June). A mouse model of X-linked adrenoleukodystrophy [Invited speaker]. Verbal presentation at the Australian New Zealand Society for Cell and Developmental Biology Inc.: Use of Genetically Modified Animals in Cell aqnd Developmental Biology, Dunedin. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. A. (2000, September). Basic biological concepts needed for genetic epidemiology. Verbal presentation at the Workshop on Genetic Epidemiology: Australasian Epidemiology Association, Wellington. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. A. (2000, November). Rapid and comprehensive determination of cytochrome P450 CYP2D6 poor metabolizer genotypes by multiplex polymerase chain reaction. Verbal presentation at the Thirt International Workshop on Advances Genomics, Japan. Conference Contribution - Verbal presentation and other Conference outputs
Martin, J. H., Begg, E. J., Kennedy, M. A., Roberts, R. L., & Barclay, M. L. (2000). Cytochrome P450 2C9 genotype does not predict incidence of gastric bleeding with non steroidal anti-inflammatory drugs. Proceedings of ASCEPT, 7(April), 57. Journal - Research Article
Rogers, G. R., Miller, A., Damak, S., & Kennedy, M. A. (2000). A mouse model of adrenoleukodystrophy: Analysis of cytokine gene expression in the brain. An oral presentation. Bulletin of the Human Genetics Society of Australasia. 13(2). NSW, Australia: SHS, Northwest Business Park. [Abstract] Conference Contribution - Published proceedings: Abstract
Kennedy, M. A. (2000). Mendelian Genetic Disorders. In The Encyclopedia of Life Sciences. London: Nature Publishing Group. Chapter in Book - Research
Roberts, R., Sullivan, P., Joyce, P. R., & Kennedy, M. A. (2000). Rapid and comprehensive determination of cytochrome P450 CYP2D6 poor metabolizer genotypes by multiplex polymerase chain reaction. Human Mutation, 16, 77-85. Journal - Research Article
Neville, L., Cameron, A. V., & Kennedy, M. A. (1999, March). Gene trapping in mouse embryonic stem cells. Verbal presentation at the Human Genome Meeting, Brisbane, Australia. Conference Contribution - Verbal presentation and other Conference outputs
Roberts, R. L., Joyce, P. R., Sullivan, P. F., & Kennedy, M. A. (1999, December). Rapid and comprehensive determination of cytochrome P450 CYP2D6 poor metabolizer genotypes by multiplez polymerase chain reaction. Verbal presentation at the FAOMB Meeting on Gene Diversity and Bioinformatics, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Littlejohn, M. D., Taylor, D. R., Miller, A. L., & Kennedy, M. A. (1999, April). Determination of 2-adrenergic receptor haplotypes by a multiplexed polymerase chain reaction assay. Verbal presentation at the Human Genome Meeting, Shanghai, China. Conference Contribution - Verbal presentation and other Conference outputs
Kennedy, M. A., Damak, S., Miller, A. P., Cameron, A. V., Rogers, G. R., Day, W. A., … Fleming, J. S., … Love, D. R. (1999). A Mouse Model of Adrenoleukodystrophy. Proceedings of the Human Genome Meeting. Brisbane, Australia: Human Genome Organisation (HUGO). [Abstract] Conference Contribution - Published proceedings: Abstract
Neville, L., Cameron, A. V., & Kennedy, M. A. (1999). Gene trapping in mouse embryonic stem cells. 9th Queenstown Molecular Biology Meeting. [Abstract] Conference Contribution - Published proceedings: Abstract
Hanrahan, V., George, P. M., & Kennedy, M. A. (1999). Instability characteristics of trinucleotide (CAG) repeat tracts in Escherichia coli. Journal of Biochemistry, Molecular Biology & Biophysics, 3, 117-125. Journal - Research Article
Hanrahan, V., & Kennedy, M. A. (1999). Structure and expression of the human homeobox gene HLX1. 14th Symposium of the Federation of Asian and Oceanic Biochemists and Molecular Biologists. [Abstract] Conference Contribution - Published proceedings: Abstract
Kennedy, M., Miller, A., Rogers, G. R., Damak, S., Sharp, P., Carey, W. A., & Love, D. R. (1998). Mouse model of adrenoleukodysrophy. Verbal presentation at the 8th Annual Queenstown Molecular Biology Meeting, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Sullivan, P. F., Fifield, W. J., Kennedy, M. A., Mulder, R. T., Sellman, J. D., & Joyce, P. R. (1998). No association between novelty seeking and the type 4 dopamine receptor gene (DRD4) in two New Zealand samples. American Journal of Psychiatry, 155, 98-101. Journal - Research Article
Dodd, A., Rowland, S., Hawkes, L. J., Kennedy, M. A., & Love, D. R. (1997). Mutations in the adrenoleukodystrophy gene. Human Mutation, 9(6), 500-511. Journal - Research Article
Sullivan, P. F., Fifield, W. J., Kennedy, M. A., Mulder, R. T., Sellman, J. D., & Joyce, P. R. (1997). Novelty seeking and a dopamine transporter gene polymorphism (DAT1). Biological Psychiatry, 42(11), 1070-1072. Journal - Research Article
Cameron, V. A., Aitken, G. D., Ellmers, L. J., Kennedy, M. A., & Espiner, E. A. (1996). The sites of gene expression of atrial, brain and C-type natriuretic peptides in mouse fetal development: Temporal changes in embryos and placenta. Endocrinology, 137(3), 817-824. doi: 10.1210/endo.137.3.8603590 Journal - Research Article
Kennedy, M. A. (1996). Internet resources for human and mouse molecular genetics. In S. R. Swindell, R. Miller & G. S. A. Myers (Eds.), Internet for the Molecular Biologist. (pp. 123-149). Norfolk: Horizon Scientific Press. Chapter in Book - Research
Kennedy, M. A., Rowland, S., Miller, A., Morris, C. M., Neville, L., Dodd, A., … Love, D. R. (1996). Structure and location of the murine adrenoleukodystrophy gene. Genomics, 32(3), 395-400. Journal - Research Article
Morris, C., Jeffs, A., Smith, T., McDonald, M., Board, P., Kennedy, M., & Fitzgerald, P. (1996). BCR gene recombines with genomically distinct sites on band 11q13 in complex BCR-ABL translocations of chronic myeloid leukemia. Oncogene, 12(3), 677-685. Journal - Research Article
Rowland, S., Dodd, A., Roche, A. L., Manilal, S., Kennedy, M. A., Becroft, D. M. O., … Love, D. R. (1996). DNA-based diagnostics for adrenoleukodystrophy in a large New Zealand family. New Zealand Medical Journal, 109, 312-315. Journal - Research Article
Neville, L., Cochrane, J., Fitzgerald, P. H., & Kennedy, M. A. (1995). Fragile X mental retardation syndrome: DNA diagnosis and carrier detection in New Zealand families. New Zealand Medical Journal, 108, 404-406. Journal - Research Article
Sowerby, S. J., Kennedy, M. A., Fitzgerald, P. H., & Morris, C. M. (1993). DNA sequence analysis of the major breakpoint cluster region of the BCR gene rearranged in Philadelphia-positive human leukemias. Oncogene, 8(6), 1679-1683. Journal - Research Article