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Martina Paumann-PageResearch Fellow

MSc PhD (Vienna)

Email martina.paumann-page@otago.ac.nz
Tel 64 3 364 0566

Research interests

Dr Martina Paumann-Page is interested in how reactions of mammalian peroxidases are involved in health and disease.

The main focus of her research is to investigate what role human peroxidasin plays in invasive metastatic melanoma and fibrosis.

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Publications

Bathish, B., Turner, R., Paumann-Page, M., Kettle, A. J., & Winterbourn, C. C. (2018). Characterisation of peroxidasin activity in isolated extracellular matrix and direct detection of hypobromous acid formation. Archives of Biochemistry & Biophysics, 646, 120-127. doi: 10.1016/j.abb.2018.03.038

Paumann-Page, M., Bathish, B., Eccles, M., & Winterbourn, C. (2018). Peroxidasin, a newly identified peroxidase, and its role in invasive metastatic melanoma. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Paumann-Page, M., Katz, R.-S., Bellei, M., Schwartz, I., Edenhofer, E., Sevcnikar, B., … Obinger, C. (2017). Pre-steady-state kinetics reveal the substrate specificity and mechanism of halide oxidation of truncation human peroxidasin 1. Journal of Biological Chemistry, 292(11), 4583-4592. doi: 10.1074/jbc.M117.775213

Grishkovskaya, I., Paumann-Page, M., Tscheliessnig, R., Stampler, J., Hofbauer, S., Soudi, M., … Obinger, C. (2017). Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation. Journal of Biological Chemistry, 292(20), 8244-8261. doi: 10.1074/jbc.M117.775031

Soudi, M., Paumann-Page, M., Delporte, C., Pirker, K. F., Bellei, M., Edenhofer, E., … Obinger, C. (2015). Multidomain human peroxidasin 1 is a highly glycosylated and stable homotrimeric high spin ferric peroxidase. Journal of Biological Chemistry, 290(17), 10876-10890. doi: 10.1074/jbc.M114.632273

Journal - Research Article

Bathish, B., Turner, R., Paumann-Page, M., Kettle, A. J., & Winterbourn, C. C. (2018). Characterisation of peroxidasin activity in isolated extracellular matrix and direct detection of hypobromous acid formation. Archives of Biochemistry & Biophysics, 646, 120-127. doi: 10.1016/j.abb.2018.03.038

Paumann-Page, M., Katz, R.-S., Bellei, M., Schwartz, I., Edenhofer, E., Sevcnikar, B., … Obinger, C. (2017). Pre-steady-state kinetics reveal the substrate specificity and mechanism of halide oxidation of truncation human peroxidasin 1. Journal of Biological Chemistry, 292(11), 4583-4592. doi: 10.1074/jbc.M117.775213

Grishkovskaya, I., Paumann-Page, M., Tscheliessnig, R., Stampler, J., Hofbauer, S., Soudi, M., … Obinger, C. (2017). Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation. Journal of Biological Chemistry, 292(20), 8244-8261. doi: 10.1074/jbc.M117.775031

Soudi, M., Paumann-Page, M., Delporte, C., Pirker, K. F., Bellei, M., Edenhofer, E., … Obinger, C. (2015). Multidomain human peroxidasin 1 is a highly glycosylated and stable homotrimeric high spin ferric peroxidase. Journal of Biological Chemistry, 290(17), 10876-10890. doi: 10.1074/jbc.M114.632273

Chapman, A. L. P., Mocatta, T. J., Shiva, S., Seidel, A., Chen, B., Khalilova, I., Paumann-Page, M. E., Jameson, G. N. L., Winterbourn, C. C., & Kettle, A. J. (2013). Ceruloplasmin is an endogenous inhibitor of myeloperoxidase. Journal of Biological Chemistry, 288(9), 6465-6477. doi: 10.1074/jbc.M112.418970

Paumann-Page, M., Furtmüller, P. G., Hofbauer, S., Paton, L. N., Obinger, C., & Kettle, A. J. (2013). Inactivation of human myeloperoxidase by hydrogen peroxide. Archives of Biochemistry & Biophysics, 539(1), 51-62. doi: 10.1016/j.abb.2013.09.004

Burner, U., Obinger, C., Paumann, M., Furtmuller, P. G., & Kettle, A. J. (1999). Transient and steady-state kinetics of the oxidation of substituted benzoic acid hydrazides by myeloperoxidase. Journal of Biological Chemistry, 274, 9494-9592. doi: 10.1074/jbc.274.14.9494

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Conference Contribution - Published proceedings: Abstract

Paumann-Page, M., Bathish, B., Eccles, M., & Winterbourn, C. (2018). Peroxidasin, a newly identified peroxidase, and its role in invasive metastatic melanoma. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

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