Dr Simon Guan

2025

Journal - Research Article

Guan, G., Rathninde, L., Friedlander, L., Hanlin, S., Polonowita, A., & Mei, L. (2025). Students’ perceived knowledge and confidence of performing extra-oral clinical examinations during Bachelor of Dental Surgery (BDS) study in New Zealand. New Zealand Medical Journal/Te ara tika o te hauora hapori, 138(1615), 20-33. Retrieved from https://www.nzmj.org.nz/

Deng, L., Guan, G., Cannon, R. D., & Mei, L. (2025). Age-related oral microbiota dysbiosis and systemic diseases. Microbial Pathogenesis, 205, 107717. doi: 10.1016/j.micpath.2025.107717

Mei, L., Au, C., Foo, S., Gao, C., Zhu, S., & Guan, G. (2025). Three-dimensional stereophotogrammetry facial morphologic signatures of temporomandibular disorders. Journal of Oral Pathology & Medicine. Advance online publication. doi: 10.1111/jop.13644

Tennekoon, S., Guan, G., Ting, G., & Li, K. C. (2025). Analysis of changes in saliva composition in patients with oral cancer and oropharyngeal cancer using Fourier-transform infrared spectroscopy. New Zealand Dental Journal, 121(1), 17-23.

Lin, Y. K., Mei, L., Narsinh, P., Tong, D., Polonowita, A., & Guan, G. (2025). Patient perceptions of the service provision at an academic oral medicine clinic. New Zealand Dental Journal, 121(1), 9-14.

Guan, G., Coates, D. E., Sun, Q., Cannon, R. D., & Mei, L. (2025). Atomic force microscopy for revealing oncological nanomechanobiology and thermodynamics. ACS Nano, 19(11), 10862-10877. doi: 10.1021/acsnano.4c14837

Mei, L., Huang, Z., Wang, Z., Sun, S., Zhu, S., Gao, C., Polonowita, A., & Guan, G. (2025). Electroencephalographic signature of TMD patients: clinical implications. British Journal of Oral & Maxillofacial Surgery. Advance online publication. doi: 10.1016/j.bjoms.2025.02.013

Wu, T., Farella, M., Guan, S., Cannon, R. D., & Mei, L. (2025). A national survey of the debonding protocols used by orthodontists in New Zealand. Australasian Orthodontic Journal, 41(1), 1-7. doi: 10.2478/aoj-2025-0001

Journal - Research Other

France, A., De Silva, H. L., Tong, D., Mei, L., & Guan, G. (2025). From tooth to vision: A decade of breakthroughs in osteo-odonto-keratoprosthesis (OOKP) and modified OOKP: Global insights into surgical techniques, outcomes, and pioneering research. Seminars in Ophthalmology. Advance online publication. doi: 10.1080/08820538.2025.2503910

Guan, G., Polonowita, A. K., Mei, L., Polonowita, D. A., & Polonowita, A. D. (2025). Chronic orofacial pain and pharmacological management: A Clinical guide. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology. Advance online publication. doi: 10.1016/j.oooo.2025.02.005

2024

Journal - Research Article

Guan, G., Tjhang, V., Sun, H., Polonowita, A., & Mei, L. (2024). Halitosis in oral lichen planus patients. Journal of Breath Research. Advance online publication. doi: 10.1088/1752-7163/ad8ee7

Guan, G., Lim, A., Sim, H., Khor, Y., & Mei, L. (2024). Interprofessional communication between general dental practitioners and general medical practitioners: A qualitative study. Journal of Primary Health Care. Advance online publication. doi: 10.1071/HC24071

Mei, L., Jin, C., Na, A., Marra, J., Guan, S., & Choi, J. (2024). Biomechanical aging behaviour of clear aligners. Australian Orthodontic Journal, 40(1), 60-66. doi: 10.2478/aoj-2024-0006)

Mei, L., Wang, Z., Guo, O., Zhang, L., & Guan, G. (2024). TikTok talks teeth: A quantitative and qualitative analysis of fixed appliance related TikTok videos. Australasian Orthodontic Journal, 40(1), 50-59. doi: 10.2478/aoj-2024-0005

Avery, N., Fukushima, K., Guan, G., Praganta, J., Rich, A., Vincent, M., & Robertson, S. (2024). Familial aggregation of keratinising desquamative squamous metaplasia in the urinary tract. BJU International, 133(Suppl. 3), 15-17. doi: 10.1111/bju.16160

Journal - Research Other

Wang, O., Mei, L., Polonowita, A., & Guan, G. (2024). Exploring the link between burning mouth syndrome and human herpesvirus-6B: A narrative review on pathogenesis. Journal of the Royal Society of New Zealand. Advance online publication. doi: 10.1080/03036758.2024.2406818

van Kuijk, M., De Silva, H., Chan, L., & Guan, G. (2024). Cribriform adenocarcinoma of the minor salivary glands: Case report and literature review. New Zealand Medical Journal/Te ara tika o te hauora hapori, 137(1599), 103-112. Retrieved from https://www.nzmj.org.nz/

Polonowita, A. D., Polonowita, A. K., Mei, L., & Guan, G. (2024). Construction of the chronic temporomandibular disorder patients: The association between neural and psychological pathways. New Zealand Medical Journal/Te ara tika o te hauora hapori, 137(1595), 80-93. Retrieved from https://www.nzmj.org.nz/

Polonowita, A., Mei, L., & Guan, G. (2024). The deconstruction of chronic orofacial pain and a hiding inhibition pathway of orofacial pain: The trigeminal proprioceptive mesencephalic periaqueductal gray pathway. New Zealand Medical Journal/Te ara tika o te hauora hapori, 137(1588), 67-79. Retrieved from https://nzmj.org.nz/

2023

Chapter in Book - Research

Guan, G., & Polonowita, A. (2023). Immunology and the oral cavity. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 319-323). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49

Polonowita, A., & Guan, G. (2023). Infection-related oral ulceration. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 217-219). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49

Polonowita, A., & Guan, G. (2023). Aphthae and recurrent aphthous stomatitis. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 213-215). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49

Polonowita, A., & Guan, G. (2023). Differential diagnosis of oral ulceration. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 205-207). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_49

Polonowita, A., & Guan, G. (2023). Traumatic oral ulceration. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 209-211). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_50

Guan, G., & Polonowita, A. (2023). Allergy and the mouth. In R. Balasubramaniam, S.-C. Yeoh, T. Yap & S. R. Prabhu (Eds.), Oral medicine: A clinical guide. (pp. 103-105). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-36797-7_24

Journal - Research Article

Au, C., Li, J., Jin, L., Wu, T., Guan, G., & Mei, L. (2023). Non-attendance of appointments at the orthodontic clinic. Australasian Orthodontic Journal, 39(2), 185-193. doi: 10.2478/aoj-2023-0035

Guan, G., Mei, L., Yu, C., Tan, Y., & Han, C. (2023). Patient-centred care attitudes and knowledge: A national study of BDS students in New Zealand. BMC Medical Education, 23, 516. doi: 10.1186/s12909-023-04496-7

Li, M., & Guan, G. (2023). Profilometry and atomic force microscopy for surface characterization. Nano TransMed, 2(1), 69-73. doi: 10.26599/NTM.2023.9130017

Journal - Research Other

El Tantawi, M., Lam, W. Y. H., Giraudeau, N., Virtanen, J. I., Matanhire, C., Chifamba, T., … Hasmun, N., Guan, G., Polonowita, A., … Folayan, M. O. (2023). Teledentistry from research to practice: A tale of nineteen countries. Frontiers in Oral Health, 4, 1188557. doi: 10.3389/froh.2023.1188557

Guan, G., Cannon, R. D., Coates, D. E., & Mei, L. (2023). Effect of the Rho-kinase/ROCK signaling pathway on cytoskeleton components. Genes, 14, 272. doi: 10.3390/genes14020272

2022

Journal - Research Article

Han, C., Mei, L., Liu, A., Ya Mohammad Hassan, S., Polonowita, A., & Guan, G. (2022). Oral medicine services: A two-centre study of 99,603 patients between 2015 and 2020. Journal of International Medical Research, 50(8). doi: 10.1177/03000605221115384

Yu, W. W., Goh, R., Cheong, E., Guan, G., Jin, C., Cannon, R. D., Farella, M., & Mei, L. (2022). Prevalence of halitosis among young adults in Dunedin, New Zealand. International Journal of Dental Hygiene, 20, 700-707. doi: 10.1111/idh.12609

Polonowita, A., Guan, G., Thomson, W. M., & Martin-Hendrie, R. (2022). Using telehealth for oral medicine patient management during the COVID-19 lockdown. Oral Surgery, 15, 291-304. doi: 10.1111/ors.12721

Ratnayake, J., Guan, G., Polonowita, A., Gray, A. R., Loch, C., Li, K. C., Waddell, J. N., Lyons, K., & Brunton, P. A. (2022). Measuring changes in jaw opening forces to assess the degree of improvement in patients with temporomandibular disorders. Applied Sciences, 12(3), 1224. doi: 10.3390/app12031224

Journal - Research Other

Guan, G., He, Y., & Mei, L. (2022). Atomic force microscopy: A nanobiotechnology for cellular research. Nano TransMed, 1, e9130004. doi: 10.26599/NTM.2022.9130004

Guan, G., Rich, A. M., Polonowita, A., & Mei, L. (2022). Review of taste and taste disturbance in COVID-19 patients. New Zealand Medical Journal, 135(1549), 81-91. Retrieved from https://www.nzma.org.nz/journal

Conference Contribution - Published proceedings: Abstract

Zainuddin, F. Z. A., Ting, G., Thomson, M., & Guan, S. (2022). Measuring dry mouth in older people in residential care in Dunedin. New Zealand Dental Journal, 118(4), (pp. 171). [Abstract]

Tennekoon, S., Li, K. C., Guan, S., Ting, G., & Kelly, L. (2022). Analysis of changes in saliva composition in patients with oral and oropharyngeal cancer using Fourier Transform Infrared Spectroscopy. New Zealand Dental Journal, 118(4), (pp. 169). [Abstract]

Sun, Q., Seo, B., Hussaini, H., Guan, S., & Rich, A. (2022). Expression of proinflammatory cytokines in cultured keratinocytes from specimens on oral lichen planus. New Zealand Dental Journal, 118(4), (pp. 166). [Abstract]

2021

Journal - Research Article

Wang, Y., Bai, S., Cheng, Q., Zeng, Y., Xu, X., & Guan, G. (2021). Naringenin promotes SDF-1/CXCR4 signaling pathway in BMSCs osteogenic differentiation. Folia Histochemica et Cytobiologica, 59(1), 66-73. doi: 10.5603/FHC.a2021.0008

Won, J., Guan, G., Mei, L., Ma, T., Lai, Y., Zafar, S., Mei, M. L., & Thomson, W. M. (2021). A multicenter study of dental curricula in Asia/Pacific nations: The views and experiences of final-year dental students. Journal of Dental Education, 85, 660-668. doi: 10.1002/jdd.12515

Journal - Research Other

Li, B., Guan, G., Mei, L., Jiao, K., & Li, H. (2021). Pathological mechanism of chondrocytes and the surrounding environment during osteoarthritis of temporomandibular joint. Journal of Cellular & Molecular Medicine, 25, 4902-4911. doi: 10.1111/jcmm.16514

Lv, N., Sun, M., Polonowita, A., Mei, L., & Guan, G. (2021). Management of oral medicine emergencies during COVID-19: A study to develop practice guidelines. Journal of Dental Sciences, 16, 493-500. doi: 10.1016/j.jds.2020.07.016

2020

Journal - Research Article

Guo, J., Li, L., Guan, G., Bennani, F., & Mei, L. (2020). Oral health knowledge and practice among orthodontic clients in China and New Zealand. Canadian Journal of Dental Hygiene / Journal canadien de l'hygiène dentaire, 54(3), 124-132.

Guo, J., Low, K. S., Mei, L., Li, J. H., Qu, W., & Guan, G. (2020). Use of traditional medicine for dental care by different ethnic groups in New Zealand. BMC Oral Health, 20, 280. doi: 10.1186/s12903-020-01272-7

Ratnayake, J., Guan, G., Polonowita, A., Li, K. C., Gray, A., Waddell, J. N., Loch, C., & Brunton, P. A. (2020). Can the measurement of jaw-opening forces assist in the diagnosis of temporomandibular disorders? Journal of Oral & Facial Pain & Headache, 34(3), 199-205. doi: 10.11607/ofph.2587

Xu, X., Shum, M., Ting, A., Mei, L., & Guan, G. (2020). Estimation of jaw-opening forces, energy expenditure and jaw-opening patterns in adults. Archives of Oral Biology, 117, 104836. doi: 10.1016/j.archoralbio.2020.104836

Guan, G., Mei, L., Polonowita, A., Hussaini, H., Seo, B., & Rich, A. M. (2020). Malignant transformation in oral lichen planus and lichenoid lesions: A 14-year longitudinal cohort study of 829 patients in New Zealand. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 130(4), 411-418. doi: 10.1016/j.oooo.2020.07.002

Mei, L., Lai, Y., Lee, P., Ng, A., Tan, K., Zafar, S., & Guan, G. (2020). Final year dental students' career plans, work patterns, work-life balance and domestic life in New Zealand and Australia. European Journal of Dental Education, 24(4), 679-686. doi: 10.1111/eje.12556

Guan, G., Lau, J., Yew, V., U, J., Qu, W., Lam, J., Polonowita, A., & Mei, L. (2020). Referrals by general dental practitioners and medical practitioners to oral medicine specialists in New Zealand: A study to develop protocol guidelines. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 130(1), 43-51.e5. doi: 10.1016/j.oooo.2020.03.050

Xu, J., Zhao, X., Zeng, J., Yu, J.-H., Guan, S., Xu, X.-M., & Mei, L. (2020). Role of autophagy in the periodontal ligament reconstruction during orthodontic tooth movement in rats. Journal of Dental Sciences, 15, 351-363. doi: 10.1016/j.jds.2020.02.005

Guo, J., Yan, X., Li, S., Van der Walt, J., Guan, G., & Mei, L. (2020). Quantitative and qualitative analyses of orthodontic-related videos on YouTube. Angle Orthodontist, 90(3), 411-418. doi: 10.2319/082019-542.1

Jiang, B., Xu, J., Zhou, Y., Mao, J., Guan, G., Xu, X., & Mei, L. (2020). Estrogen enhances osteogenic differentiation of human periodontal ligament stem cells by activating the Wnt/β-catenin signaling pathway. Journal of Craniofacial Surgery, 31, 583-587. doi: 10.1097/scs.0000000000006226

Ratnayake, J. T., Ross, E. D., Dias, G. J., Shanafelt, K. M., Taylor, S. S., Gould, M. L., Guan, G., & Cathro, P. R. (2020). Preparation, characterisation and in-vitro biocompatibility study of a bone graft developed from waste bovine teeth for bone regeneration. Materials Today Communications, 22, 100732. doi: 10.1016/j.mtcomm.2019.100732

Journal - Research Other

Sun, M., Lv, N., Xiao, Y., Li, J., & Guan, G. (2020). A rare case of accessory maxilla: A case report and literature review of Tessier no. 7 clefts. Journal of International Medical Research, 48(5), 1-9. doi: 10.1177/0300060520925680

Guan, G., Won, J., Mei, L., & Polonowita, A. (2020). Extensive adipose replacement of the parotid glands: An unusual presentation of sialadenosis: A case report and literature review. Oral Surgery, 13, 41-47. doi: 10.1111/ors.12442

2019

Conference Contribution - Published proceedings: Abstract

Ratnayake, J., Guan, S., Polonowita, A., Li, K. C., Waddell, N., Loch, C., Gray, A., & Brunton, P. (2019). Can the measurement of jaw-opening forces assist in diagnosing temporomandibular-disorders? Journal of Dental Research, 98(A), 0179. Retrieved from https://iadr.abstractarchives.com

Ratnayake, J., Ross, E., Dias, G., Guan, S., & Cathro, P. (2019). Development and characterisation of a novel bone-graft from bovine teeth. Journal of Dental Research, 98(A), 0490. Retrieved from https://iadr.abstractarchives.com

Cathro, P., Ratnayake, J., Dias, G., Ross, E., Shanafelt, K., Taylor, S., & Guan, S. (2019). Biocompatibility and bioactivity of a novel bone graft material developed from the dentine of waste bovine teeth. International Endodontic Journal, 52(Suppl. 1), (pp. 12). doi: 10.1111/iej.13172

2018

Journal - Research Article

Wilson, E., Grant, B., Tobin-Stickings, R., Lewthwaite, H., Franklin, G., Oh, S., Guan, S., Borowsky, T., Thwaites, K., Leaper, T., Lee, J., Jack, S., & Sopoaga, F. (2018). Traditional medicine use in the Pacific community in Dunedin New Zealand. Pacific Health Dialog, 21(1), 17-26. doi: 10.26635/phd.2018.903

Guan, G., Bakr, M. M., Firth, N., & Love, R. M. (2018). Expression of cyclin D1 correlates with p27^KIP1 and regulates the degree of oral dysplasia and squamous cell carcinoma differentiation. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 126(2), 174-183. doi: 10.1016/j.oooo.2018.01.015

Journal - Research Other

Guan, G., & Mei, L. (2018). A case series: Zinc deficiency as a potential contributor to oral dysgeusia. Modern Approaches in Dentistry & Oral Health Care, 2(5), 198-203. doi: 10.32474/MADOHC.2018.02.000146

Bakr, M. M., Guan, S., Firth, N., & Love, R. M. (2018). Cyclin D1 and P27KIP1: The gatekeepers of dysplasia. Journal of Immunological Sciences, 2(3), 30-39. doi: 10.29245/2578-3009/2018/3.1142

2015

Journal - Research Article

Guan, G., & Firth, N. (2015). Oral manifestations as an early clinical sign of acute myeloid leukaemia: A case report. Australian Dental Journal, 60(1), 123-127. doi: 10.1111/adj.12272

Conference Contribution - Published proceedings: Abstract

Guan, S., Firth, N., & Love, R. (2015). Expression of cyclin D1 and its correlation with p27KIP1 in normal oral mucosa, oral dysplasia and oral squamous cell carcinoma. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 119(3), (pp. e201). doi: 10.1016/j.oooo.2014.07.440