Professor Richard Cannon

2024

Journal - Research Article

Zhao, X., Zhang, W., Jiang, F., Chen, X., Wang, M., Chen, B., Cannon, R. D., … Zhou, X. (2024). Excessive palmitic acid disturbs macrophage α-ketoglutarate/succinate metabolism and causes adipose tissue insulin resistance associated with gestational diabetes mellitus. Free Radical Biology & Medicine, 222, 424-436. doi: 10.1016/j.freeradbiomed.2024.06.029

Krishnan, C. S., Li, K. C., Tompkins, G. R., Lyons, K. M., & Cannon, R. D. (2024). Effects of simulated long-term exposure to bottled, neutral pH electrolyzed oxidizing water on the properties of denture base resins. Journal of Prosthetic Dentistry. Advance online publication. doi: 10.1016/j.prosdent.2024.03.034

2023

Chapter in Book - Other

Cannon, R. D., Lyons, K. M., Chong, K., Newsham-West, K., Niimi, K., & Holmes, A. R. (2023). Adhesion of yeast and bacteria to oral surfaces. In G. J. Seymour, M. P. Cullinan, N. C. K. Heng & P. R. Cooper (Eds.), Oral biology: Molecular techniques and applications: Methods in molecular biology (Vol. 2588). (3rd ed.) (pp. 131-156). New York, NY: Springer. doi: 10.1007/978-1-0716-2780-8_9

Journal - Research Article

Chen, X., He, Q., Zhai, Q., Tang, H., Li, D., Zhu, X., … Cannon, R. D., Mei, L., … Chen, T. (2023). Adaptive nanoparticle-mediated modulation of mitochondrial homeostasis and inflammation to enhance infected bone defect healing. ACS Nano, 17(22), 22960-22978. doi: 10.1021/acsnano.3c08165

Li, M., Li, D., Jiang, Y., He, P., Li, Y., Wu, Y., … Cannon, R. D., Mei, L., … Yuan, H. (2023). The genetic background determines material-induced bone formation through the macrophage-osteoclast axis. Biomaterials, 302, 122356. doi: 10.1016/j.biomaterials.2023.122356

Friedlander, L. T., Wallace, W. D. A., Broadbent, J. M., Hanlin, S. M., Lyons, K. M., Cannon, R. D., & Cooper, P. R. (2023). Preparedness and competency of New Zealand graduates for general dental practice: Perceptions from the workforce. Australian Dental Journal. Advance online publication. doi: 10.1111/adj.12981

Krishnan, C. S., Lyons, K. M., Tompkins, G. R., & Cannon, R. D. (2023). Storage-related stability and antimicrobial efficacy of bottled, neutral-pH Electrolysed Oxidising Water. Journal of Dentistry, 137, 104656. doi: 10.1016/j.jdent.2023.104656

Shi, J., Ma, D., Gao, S., Long, F., Wang, X., Pu, X., Cannon, R. D., & Han, T.-L. (2023). Probiotic Escherichia coli Nissle 1917-derived outer membrane vesicles modulate the intestinal microbiome and host gut-liver metabolome in obese and diabetic mice. Frontiers in Microbiology, 14, 1219763. doi: 10.3389/fmicb.2023.1219763

Jian, G., Li, D., Ying, Q., Chen, X., Zhai, Q., Wang, S., Mei, L., Cannon, R. D., … Chen, T. (2023). Dual photo-enhanced interpenetrating network hydrogel with biophysical and biochemical signals for infected bone defect healing. Advanced Healthcare Materials, 2300469. Advance online publication. doi: 10.1002/adhm.202300469

Skilbeck, M. G., Cannon, R. D., Farella, M., & Mei, L. (2023). The effect of surface roughening of orthodontic elastomers on hydrophobicity and in vitro adherence of Streptococcus gordonii. Journal of the Mechanical Behavior of Biomedical Materials, 143, 105881. doi: 10.1016/j.jmbbm.2023.105881

Liu, N., Zhong, Y., Pang, X., Li, M., Cannon, R. D., Mei, L., … Ji, P. (2023). The nano-windmill exerts superior anti-inflammatory effects via reducing choline uptake to inhibit macrophage activation. Cell Proliferation, 56, e13470. doi: 10.1111/cpr.13470

Hu, S., Yang, Z., Zhai, Q., Li, D., Zhu, X., He, Q., … Cannon, R. D., … Chen, T. (2023). An all-in-one “4A Hydrogel”: Through first-aid hemostatic, antibacterial, antioxidant, and angiogenic to promoting infected wound healing. Small. Advance online publication. doi: 10.1002/smll.202207437

Hu, S., Wang, S., He, Q., Li, D., Xin, L., Xu, C., … Mei, L., Cannon, R. D., … Chen, T. (2023). A mechanically reinforced super bone glue makes a leap in hard tissue strong adhesion and augmented bone regeneration. Advanced Science, 10, 2206450. doi: 10.1002/advs.202206450

Lyons, K. M., Cannon, R. D., Beumer, III, J., Bakr, M. M., & Love, R. M. (2023). Microbial analysis of obturators during maxillofacial prosthodontic treatment over an 8-year period. Cleft Palate Craniofacial Journal, 30(11), 1426-1441. doi: 10.1177/10556656221104940

Journal - Research Other

Krishnan, C. S., Tompkins, G. R., Lyons, K. M., & Cannon, R. D. (2023). Electrolysed oxidising water as a multi-purpose biocide in dental healthcare: A scoping review. Gerodontology, 40, 422-462. doi: 10.1111/ger.12712

Wu, Q., Xia, Y., Xiong, X., Duan, X., Pang, X., Zhang, F., … Mei, L., Cannon, R. D., … Ou, Z. (2023). Focused ultrasound-mediated small-molecule delivery to potentiate immune checkpoint blockade in solid tumors. Frontiers in Pharmacology, 14, 1169608. doi: 10.3389/fphar.2023.1169608

Guan, G., Cannon, R. D., Coates, D. E., & Mei, L. (2023). Effect of the Rho-kinase/ROCK signaling pathway on cytoskeleton components. Genes, 14, 272. doi: 10.3390/genes14020272

2022

Journal - Research Article

Chen, X., Zhao, X., Jones, M. B., Harper, A., de Seymour, J. V., Yang, Y., … Cannon, R. D., … Baker, P. N. (2022). The relationship between hair metabolites, air pollution exposure and gestational diabetes mellitus: A longitudinal study from pre-conception to third trimester. Frontiers in Endocrinology, 13, 1060309. doi: 10.3389/fendo.2022.1060309

James, J. E., Santhanam, J., Cannon, R. D., & Lamping, E. (2022). Voriconazole treatment induces a conserved sterol/pleiotropic drug resistance regulatory network, including an alternative ergosterol biosynthesis pathway, in the clinically important FSSC species, Fusarium keratoplasticum. Journal of Fungi, 8(10), 1070. doi: 10.3390/jof8101070

Zhong, W., Wang, X., Yang, L., Wang, Y., Xiao, Q., Yu, S., Cannon, R. D., … Song, J. (2022). Nanocarrier-assisted delivery of metformin boosts remodeling of diabetic periodontal tissue via cellular exocytosis-mediated regulation of endoplasmic reticulum homeostasis. ACS Nano, 16, 19096-19113. doi: 10.1021/acsnano.2c08146

Gil, F., Laiolo, J., Bayona-Pacheco, B., Cannon, R. D., Ferreira-Pereira, A., & Carpinella, M. C. (2022). Extracts from Argentinian native plants reverse fluconazole resistance in Candida species by inhibiting the efflux transporters Mdr1 and Cdr1. BMC Complementary Medicine & Therapies, 22(1), 264. doi: 10.1186/s12906-022-03745-4

James, J. E., Santhanam, J., Zakaria, L., Mamat Rusli, N., Abu Bakar, M., Suetrong, S., … Lamping, E., & Cannon, R. D. (2022). Morphology, phenotype, and molecular identification of clinical and environmental Fusarium solani species complex isolates from Malaysia. Journal of Fungi, 8(8), 845. doi: 10.3390/jof8080845

Yu, W. W., Goh, R., Cheong, E., Guan, G., Jin, C., Cannon, R. D., Farella, M., & Mei, L. (2022). Prevalence of halitosis among young adults in Dunedin, New Zealand. International Journal of Dental Hygiene, 20, 700-707. doi: 10.1111/idh.12609

Liu, Y., Xia, Y.-Y., Zhang, T., Yang, Y., Cannon, R. D., Mansell, T., … Baker, P. N. (2022). Complex interactions between circulating fatty acid levels, desaturase activities, and the risk of gestational diabetes mellitus: A prospective cohort study. Frontiers in Nutrition, 9, 919357. doi: 10.3389/fnut.2022.919357

Ratnayake, J., Veerasamy, A., Ahmed, H., Coburn, D., Loch, C., Gray, A. R., Lyons, K. M., Heng, N. C. K., Cannon, R. D., … Brunton, P. A. (2022). Clinical and microbiological evaluation of a chlorhexidine-modified glass ionomer cement (GIC-CHX) restoration placed using the atraumatic restorative treatment (ART) technique. Materials, 15, 5044. doi: 10.3390/ma15145044

Zhu, J., Song, G., Zhou, X., Han, T.-L., Yu, X., Chen, H., … Cannon, R. D., … Zhang, H. (2022). CD39/CD73 dysregulation of adenosine metabolism increases decidual natural killer cell cytotoxicity: Implications in unexplained recurrent spontaneous abortion. Frontiers in Immunology, 13, 813218. doi: 10.3389/fimmu.2022.813218

Li, D., Chen, K., Tang, H., Hu, S., Xin, L., Jing, X., … Mei, L., Cannon, R. D., … Chen, T. (2022). A logic-based diagnostic and therapeutic hydrogel with multi-stimuli responsiveness to orchestrate diabetic bone regeneration. Advanced Materials, 34, 2108430. doi: 10.1002/adma.202108430

Niimi, M., Niimi, K., Tanabe, K., Cannon, R. D., & Lamping, E. (2022). Inhibitor resistant mutants give important insights into Candida albicans ABC transporter Cdr1 substrate specificity and help elucidate efflux pump inhibition. Antimicrobial Agents & Chemotherapy, 66(1), e01748-21. doi: 10.1128/aac.01748-21

Atieh, M. A., Guirguis, M., Alsabeeha, N. H. M., & Cannon, R. D. (2022). The diagnostic accuracy of saliva testing for SARS-CoV-2: A systematic review and meta-analysis. Oral Diseases, 28(Suppl. 2), 2347-2361. doi: 10.1111/odi.13934

Skilbeck, M. G., Mei, L., Mohammed, H., Cannon, R. D., & Farella, M. (2022). The effect of ligation methods on biofilm formation in patients undergoing multi-bracketed fixed orthodontic therapy: A systematic review. Orthodontics & Craniofacial Research, 25, 14-30. doi: 10.1111/ocr.12503

Journal - Research Other

Zhao, M.-L., Zhang, F.-J., Jiang, W.-R., Xia, Y., Chen, C., Zhang, T., … Mei, P., … Thomson, M., … Cannon, R. D., … Ji, P. (2022). Investigating the impact of oral health on pregnancy and offspring outcomes: Protocol for the Lifetime Impact of ORal heAlth (LIORA) cohort study. BMJ Open, 12(11), e066204. doi: 10.1136/bmjopen-2022-066204

Cannon, R. D. (2022). Oral fungal infections: Past, present, and future. Frontiers in Oral Health, 3, 838639. doi: 10.3389/froh.2022.838639

Conference Contribution - Published proceedings: Abstract

Krishnan, C., Li, K. C., Lyons, K., Lamping, E., Tompkins, G., & Cannon, R. (2022). Evaluating the suitability of Electrolysed Oxidising Water as a denture disinfectant. New Zealand Dental Journal, 118(4), (pp. 169). [Abstract]

Cannon, R. (2022). Oral fungal infections: The benefit of sticking around [Keynote]. New Zealand Dental Journal, 118(4), (pp. 165). [Abstract]

Krishnan, C. S., Li, K. C., Lyons, K. M., Tompkins, G. R., & Cannon, R. D. (2022). Evaluating the suitability of electrolysed oxidising water as a denture disinfectant. In L. Wilson, H. Harcombe, P. Jayakaran, L. Burga, J. Antony, K. Morgaine, M. Garelja, A. Middleton, M. Anwar & T. Milne (Eds.), Proceedings of the 263rd Otago Medical School Research Society (OMSRS) Meeting: PhD Student Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839

Larcombe, M., Norris, P., Cannon, R., & Stokes, T. (2022). Research impact in health sciences research: A scoping review. Proceedings of the New Zealand Primary Care Research Colloquium. (pp. 6). Retrieved from https://www.auckland.ac.nz/en/fmhs/about-the-faculty/soph/sections-departments-centres/general-practice-and-primary-health-care/research-interests.html

2021

Journal - Research Article

Loch, C., Beckett, D., Kawe-Small, T., Cannon, R. D., Foster Page, L. A., Te Morenga, L., & Smith, L. A. (2021). Sugar in your diet: Kino te pai! An evaluation of oral health science outreach and community impact. International Journal of Health Promotion & Education. Advance online publication. doi: 10.1080/14635240.2021.2004439

Itskovich, Y., Meikle, M. C., Cannon, R. D., Farella, M., Coates, D. E., & Milne, T. J. (2021). Differential behaviour and gene expression in 3D cultures of femoral- and calvarial-derived human osteoblasts under a cyclic compressive mechanical load. European Journal of Oral Sciences, 129, e12818. doi: 10.1111/eos.12818

James, J. E., Lamping, E., Santhanam, J., & Cannon, R. D. (2021). PDR transporter ABC1 is involved in the innate azole resistance of the human fungal pathogen Fusarium keratoplasticum. Frontiers in Microbiology, 12, 673206. doi: 10.3389/fmicb.2021.673206

Madani, G., Lamping, E., Lee, H. J., Niimi, M., Mitra, A. K., & Cannon, R. D. (2021). Small-scale plasma membrane preparation for the analysis of Candida albicans Cdr1-mGFPHis. Journal of Visualized Experiments, 172, e62592. doi: 10.3791/62592

Nguyen, H. T., Zhang, R., Inokawa, N., Oura, T., Chen, X., Iwatani, S., … Holmes, A. R., Cannon, R. D., & Kajiwara, S. (2021). Candida albicans Bgl2p, Ecm33p, and Als1p proteins are involved in adhesion to saliva-coated hydroxyapatite. Journal of Oral Microbiology, 13(1), 1879497. doi: 10.1080/20002297.2021.1879497

Madani, G., Lamping, E., & Cannon, R. D. (2021). Engineering a cysteine-deficient functional Candida albicans Cdr1 molecule reveals a conserved region at the cytosolic apex of ABCG transporters important for correct folding and trafficking of Cdr1. mSphere, 6(1), e01318-20. doi: 10.1128/mSphere.01318-20

Zhang, T., Jiang, W.-R., Xia, Y.-Y., Mansell, T., Saffery, R., Cannon, R. D., … Baker, P. N. (2021). Complex patterns of circulating fatty acid levels in gestational diabetes mellitus subclasses across pregnancy. Clinical Nutrition, 40, 4140-4148. doi: 10.1016/j.clnu.2021.01.046

Prasad, S., Ramanan, D., Bennani, H., Paulin, M., Cannon, R. D., Palla, S., & Farella, M. (2021). Associations among masticatory muscle activity, physical activity and self-reported oral behaviours in adult women. Clinical Oral Investigations, 25, 5049-5059. doi: 10.1007/s00784-021-03816-9

Conference Contribution - Published proceedings: Abstract

Lamping, E., Niimi, M., Niimi, K., & Cannon, R. D. (2021). Substrate specificity of Candida albicans ATP-binding casette transporter Cdr1 responsible for multidrug resistance. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 62). Retrieved from https://www.faobmb2021.org

Thiyahuddin, N., Rich, A. M., Lamping, E., & Cannon, R. D. (2021). Microevolution of Candida albicans strains in older people with low salivary flow. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 132(1), (pp. e48). doi: 10.1016/j.oooo.2021.03.172

2020

Journal - Research Article

James, J. E., Lamping, E., Santhanam, J., Milne, T. J., Razak, M. F. A., Zakaria, L., & Cannon, R. D. (2020). A 23 bp cyp51A promoter deletion associated with voriconazole resistance in clinical and environmental isolates of Neocosmospora keratoplastica. Frontiers in Microbiology, 11, 272. doi: 10.3389/fmicb.2020.00272

Journal - Research Other

Broadbent, J. M., Loch, C., & Cannon, R. D. (2020). Dental research in New Zealand, past, present, and future. Journal of the Royal Society of New Zealand, 50(1), 1-3. doi: 10.1080/03036758.2020.1736587

Lyons, K. M., Cannon, R. D., Beumer, III, J., Bakr, M. M., & Love, R. M. (2020). The role of biofilms and material surface characteristics in microbial adhesion to maxillary obturator materials: A literature review. Cleft Palate-Craniofacial Journal, 57(4), 487-498. doi: 10.1177/1055665619882555

Wu, J., Cannon, R. D., Ji, P., Farella, M., & Mei, L. (2020). Halitosis: Prevalence, risk factors, sources, measurement, and treatment: A review of the literature. Australian Dental Journal, 65, 4-11. doi: 10.1111/adj.12725

Other Research Output

Larcombe, M., Coleman, M., Stokes, T., Cannon, R., Lübcke, A., & Smith, S. (2020). Impacts of research. Dunedin, New Zealand: Division of Health Sciences, University of Otago. 68p. Dunedin, New Zealand: Division of Health Sciences, University of Otago. Retrieved from http://hdl.handle.net/10523/10173

2019

Journal - Research Article

Meredith, L., Mei, L., Farella, M., & Cannon, R. D. (2019). Bacterial adhesion to human enamel after enameloplasty. New Zealand Dental Journal, 115(3), 103-107.

Jiang, Q., Mei, L., Zou, Y., Ding, Q., Cannon, R. D., Chen, H., & Li, H. (2019). Genetic polymorphisms in FGFR2 underlie skeletal malocclusion. Journal of Dental Research, 98(12), 1340-1347. doi: 10.1177/0022034519872951

Ghazal, A. R. A., Idris, G., Hajeer, M. Y., Alawer, K., & Cannon, R. D. (2019). Efficacy of removing Candida albicans from orthodontic acrylic bases: An in vitro study. BMC Oral Health, 19, 71. doi: 10.1186/s12903-019-0765-x

Benic, G. Z., Farella, M., Morgan, X. C., Viswam, J., Heng, N. C., Cannon, R. D., & Mei, L. (2019). Oral probiotics reduce halitosis in patients wearing orthodontic braces: A randomized, triple-blind, placebo-controlled trial. Journal of Breath Research, 13, 036010. doi: 10.1088/1752-7163/ab1c81

Han, T.-L., Cannon, R. D., Gallo, S. M., & Villas-Bôas, S. G. (2019). A metabolomic study of the effect of Candida albicans glutamate dehydrogenase deletion on growth and morphogenesis. npj Biofilms & Microbiomes, 5, 13. doi: 10.1038/s41522-019-0086-5

Mohd Thiyahuddin, N., Lamping, E., Rich, A. M., & Cannon, R. D. (2019). Yeast species in the oral cavities of older people: A comparison between people living in their own homes and those in rest homes. Journal of Fungi, 5(2), 30. doi: 10.3390/jof5020030

Prasad, S., Paulin, M., Cannon, R. D., Palla, S., & Farella, M. (2019). Smartphone-assisted monitoring of masticatory muscle activity in freely moving individuals. Clinical Oral Investigations, 23, 3601-3611. doi: 10.1007/s00784-018-2785-3

Tanabe, K., Bonus, M., Tomiyama, S., Miyoshi, K., Nagi, M., Niimi, K., … Cannon, R. D., Niimi, M., & Lamping, E. (2019). FK506 resistance of Saccharomyces cerevisiae Pdr5 and Candida albicans Cdr1 involves mutations in the transmembrane domains and extracellular loops. Antimicrobial Agents & Chemotherapy, 63(1), e01146-18. doi: 10.1128/aac.01146-18

Conference Contribution - Published proceedings: Abstract

Kumar, M., Lee, H. J., Cannon, R., & Lamping, E. (2019). Confirmation of three predicted disulphide bonds in Candida albicans Cdr1. Journal of Dental Research, 98(A), 0800. Retrieved from https://iadr.abstractarchives.com

Larcombe, M., Stokes, T., Coleman, M., & Cannon, R. (2019). From research to impact: How do we get there? (update of study in progress). Proceedings of the Academic General Practice & Primary Care Research Symposium. (pp. 5-6). Hamilton, New Zealand: University of Waikato. Retrieved from https://www.otago.ac.nz/wellington/otago730914.pdf

Mohd Thiyahuddin, N., Lamping, E., Rich, A., & Cannon, R. D. (2019). Yeast species in the oral cavities of older people. New Zealand Dental Journal, 115, (pp. 165-166). [Abstract]

Thiyahuddin, N., Cannon, R., Lamping, E., & Rich, A. (2019). Candida species and strains in the oral cavities of the elderly: A comparison between people in home-based care and in aged-care facilities. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 128(1), (pp. e69). doi: 10.1016/j.oooo.2019.02.167

Conference Contribution - Verbal presentation and other Conference outputs

Madani, G., Lamping, E., Bostina, M., Raunser, S., Hall, N., Mitra, A., & Cannon, R. D. (2019, September). Expression, purification, and negative staining of Candida albicans plasma membrane protein Cdr1. Verbal presentation at the Sir John Walsh Research Institute Research Day, Dunedin, New Zealand.

Prasad, S., Paulin, M., Cannon, R., & Farella, M. (2019, August-September). Monitoring masticatory muscle activity by a smart-phone assisted wearable device. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2018

Journal - Research Article

Zhang, N., Wheeler, D., Truglio, M., Lazzarini, C., Upritchard, J., McKinney, W., … Cannon, R. D., Broadbent, R. S., … Schmid, J. (2018). Multi-locus next-generation sequence typing of DNA extracted from pooled colonies detects multiple unrelated Candida albicans strains in a significant proportion of patient samples. Frontiers in Microbiology, 9, 1179. doi: 10.3389/fmicb.2018.01179

Al-Dujaili, M., Milne, T. J., Cannon, R. D., & Farella, M. (2018). Postnatal expression of chondrogenic and osteogenic regulatory factor mRNA in the rat condylar cartilage. Archives of Oral Biology, 93, 126-132. doi: 10.1016/j.archoralbio.2018.05.019

Conference Contribution - Published proceedings: Abstract

Chen, W. T., Chen, Y. E., Cheong, D., Adam, L., Tompkins, G., & Cannon, R. (2018). Comparing the microbiology syllabi between the world's top dental schools. Journal of Dental Research, 97(Spec. Iss. B), 1530. Retrieved from http://www.iadr.org

Mei, L., Benic, G., Cannon, R., & Farella, M. (2018). Efficacy of oral probiotics in managing biofilm formation in orthodontic patients: A triple-blind randomised placebo-controlled trial. European Journal of Orthodontics, 40(5), (pp. e18). doi: 10.1093/ejo/cjy060

Madani, G., Lamping, E., Ha, N. C., Mitra, A. K., & Cannon, R. D. (2018). Expression and purification of Candida albicans multidrug efflux pump Cdr1 for structural studies. New Zealand Dental Journal, 114(4), (pp. 189). [Abstract]

Mei, L., Benic, G., Cannon, R. D., Heng, N., Morgan, X., & Farella, M. (2018). Efficacy of oral probiotics in managing biofilm formation in patients wearing fixed orthodontic appliances. New Zealand Dental Journal, 114(4), (pp. 184-185). [Abstract]

Niimi, M., Niimi, K., Saiwan, S., Assavachin, S., Chindamporn, A., Cannon, R. D., & Lamping, E. (2018). Mapping the interaction of the Candida albicans multidrug resistance ABC protein Cdr1 with pump inhibitor clorgyline that stimulates ATPase activity. Medical Mycology, 56(Suppl. 2), (pp. S60). doi: 10.1093/mmy/myy036

Niimi, K., Lamping, E., Watanasrisin, W., Yurayart, C., Saiwan, S., Chindamporn, A., Cannon, R. D., & Niimi, M. (2018). K577 in intracellular loop 1 of C. albicans ABC transporter Cdr1 plays a critical role in drug transport. Medical Mycology, 56(Suppl. 2), (pp. S132). doi: 10.1093/mmy/myy036

Nguyen, H. T., Inokawa, N., Zhang, R., Iwatani, S., Holmes, A. R., Cannon, R. D., & Kajiwara, S. (2018). Involvement of Candida albicans Bgl2p, Ecm33p and Als1p in adherence to saliva-coated surfaces. Medical Mycology, 56(Suppl. 2), (pp. S133). doi: 10.1093/mmy/myy036

Conference Contribution - Poster Presentation (not in published proceedings)

Madani, G., Lamping, E., & Cannon, R. (2018, September). Structural characterization of the archetypal fungal efflux pump Candida Albicans Cdr1. Poster session presented at the Otago Spotlight Symposium on Infectious Disease, Wellington, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Madani, G., Lamping, E., Hall, N., Mitra, A., & Cannon, R. D. (2018, March). Expression and purification of Candida albicans multidrug efflux pump Cdr1 for structural studies. Verbal presentation at the ABC2018 Conference: The 7th Federation of European Biochemical Societies (FEBS) Special Meeting on ABC Proteins, Innsbruck, Austria.

Other Research Output

Loch, C., Beckett, D. M., Cannon, R., Foster Page, L., Te Morenga, L., Kawe-Small, T. (2018, June). Community-based dental science outreach: The sugar in your diet: Kino Te Pai! experience. New Zealand Dental and Oral Health Therapists Association (NZDOHTA) Invercargill CPD Roadshow, Invercargill, New Zealand. [Research Presentation].

2017

Chapter in Book - Research

Lamping, E., Madani, G., Lee, H. J., Niimi, M., & Cannon, R. D. (2017). Structure-function analyses of multidrug tansporters. In R. Prasad (Ed.), Candida albicans: Cellular and molecular biology. (2nd ed.) (pp. 379-406). Springer. doi: 10.1007/978-3-319-50409-4

Cannon, R. D., Lyons, K. M., Chong, K., Newsham-West, K., Niimi, K., & Holmes, A. R. (2017). Adhesion of yeast and bacteria to oral surfaces. In G. J. Seymour, M. P. Cullinan & N. C. K. Heng (Eds.), Oral biology: Molecular techniques and applications: Methods in molecular biology (Vol. 1537). (2nd ed.) (pp. 165-190). New York, NY: Springer. doi: 10.1007/978-1-4939-6685-1_10

Journal - Research Article

Meredith, L., Mei, L., Cannon, R. D., & Farella, M. (2017). Interproximal reduction in orthodontics: Why, where, how much to remove? Australasian Orthodontic Journal, 33(2), 150-157.

Wang, Y., Li, J., Sun, W., Li, H., Cannon, R. D., & Mei, L. (2017). Effect of non-fluoride agents on the prevention of dental caries in primary dentition: A systematic review. PLoS ONE, 12(8), e0182221. doi: 10.1371/journal.pone.0182221

Weerasekera, M. M., Sissons, C. H., Wong, L., Anderson, S. A., & Cannon, R. D. (2017). Denaturant gradient gel electrophoresis profiles of bacteria from the saliva of twenty four different individuals form clusters that showed no relationship to the yeasts present. Archives of Oral Biology, 82, 6-10. doi: 10.1016/j.archoralbio.2017.05.014

Meredith, L., Farella, M., Lowrey, S., Cannon, R. D., & Mei, L. (2017). Atomic force microscopy analysis of enamel nanotopography after interproximal reduction. American Journal of Orthodontics & Dentofacial Orthopedics, 151(4), 750-757. doi: 10.1016/j.ajodo.2016.09.021

Lamping, E., Zhu, J.-y., Niimi, M., & Cannon, R. D. (2017). Role of ectopic gene conversion in the evolution of a Candida krusei pleiotropic drug resistance transporter family. Genetics, 205(4), 1619-1639. doi: 10.1534/genetics.116.194811

Choo, K. H., Lee, H. J., Knight, N. J., Holmes, A. R., & Cannon, R. D. (2017). Multilocus sequence typing (MLST) analysis of Candida albicans isolates colonizing acrylic dentures before and after denture replacement. Medical Mycology, 55(6), 673-679. doi: 10.1093/mmy/myw128

Conference Contribution - Published proceedings: Abstract

Cannon, R., Beckett, D., Waddell, J., Brunton, P., & Loch, C. (2017). Engaging children with oral health and dental science: The Otago experience. Journal of Dental Research, 96(Spec. Iss. B). Retrieved from http://www.iadr.org

Madani, G., Lamping, E., & Cannon, R. D. (2017). Purification of Cdr1 as a first step to overcome drug resistant Candida infections. New Zealand Dental Journal, 113(4), (pp. 56-57). [Abstract]

Lee, H. J., Lamping, E., & Cannon, R. D. (2017). Extracellular loop amino acid residues essential for Candida albicans Cdr1 multidrug efflux pump function. New Zealand Dental Journal, 113(4), (pp. 56). [Abstract]

Zhang, N., Wheeler, D., Truglio, M., Lazzarini, C., Upritchard, J., McKinney, W., … Cannon, R. D., Broadbent, R., … Schmid, J. (2017). A method for the detection and simultaneous typing of multiple Candida albicans strains co-existing at the same human body sites. Proceedings of the New Zealand Microbiological Society (NZMS) Annual Conference. 123. Retrieved from http://www.nzmsconference.org.nz/

Lamping, E., Lee, H. J., & Cannon, R. D. (2017). New structural and functional insights into the type II fungal ATP-binding cassette transporter Candida albicans Cdr1. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 746. Retrieved from http://gen2017.w.events4you.currinda.com

Knight, N., Lyons, K., & Cannon, R. (2017). Colonization of acrylic dentures by Candida species. Journal of Dental Research, 96(Spec. Iss. A), 0206. Retrieved from http://www.iadr.org

Conference Contribution - Verbal presentation and other Conference outputs

Madani, G., Lamping, E., Lee, H. J., & Cannon, R. (2017, September). Candida albicans Cdr1 cysteines are critical for pump function. Verbal presentation at the IADR New Zealand Section Colgate Poster Competition 2017, Adelaide, SA.

2016

Journal - Research Article

van der Wielen, P. A., Holmes, A. R., & Cannon, R. D. (2016). Secretory component mediates Candida albicans binding to epithelial cells. Oral Diseases, 22(1), 69-74. doi: 10.1111/odi.12397

Tong, Y., Liu, M., Zhang, Y., Liu, X., Huang, R., Song, F., … Cannon, R. D., … Zhang, L. (2016). Beauvericin counteracted multi-drug resistant Candida albicans by blocking ABC transporters. Synthetic & Systems Biotechnology, 1(3), 158-168. doi: 10.1016/j.synbio.2016.10.001

Holmes, A. R., Cardno, T. S., Strouse, J. J., Ivnitski-Steele, I., Keniya, M. V., Lackovic, K., Monk, B. C., … Cannon, R. D. (2016). Targeting efflux pumps to overcome antifungal drug resistance. Future Medicinal Chemistry, 8(12), 1485-1501. doi: 10.4155/fmc-2016-0050

Rawal, M. K., Banerjee, A., Shah, A. H., Khan, M. F., Sen, S., Saxena, A. K., Monk, B. C., Cannon, R. D., … Prasad, R. (2016). Newly identified motifs in Candida albicans Cdr1 protein nucleotide binding domains are pleiotropic drug resistance subfamily-specific and functionally asymmetric. Scientific Reports, 6, 27132. doi: 10.1038/srep27132

Farella, M., Loke, C., Sander, S., Songini, A., Allen, M., Mei, L., & Cannon, R. D. (2016). Simultaneous wireless assessment of intra-oral pH and temperature. Journal of Dentistry, 51, 49-55. doi: 10.1016/j.jdent.2016.05.012

Watanasrisin, W., Iwatani, S., Oura, T., Tomita, Y., Ikushima, S., Chindamporn, A., Niimi, M., Niimi, K., Lamping, E., Cannon, R. D., & Kajiwara, S. (2016). Identification and characterization of Candida utilis multidrug efflux transporter CuCdr1p. FEMS Yeast Research, 16, fow042. doi: 10.1093/femsyr/fow042

Panapruksachat, S., Iwatani, S., Oura, T., Vanittanakom, N., Chindamporn, A., Niimi, K., Niimi, M., Lamping, E., Cannon, R. D., & Kajiwara, S. (2016). Identification and functional characterization of Penicillium marneffei pleiotropic drug resistance transporters ABC1 and ABC2. Medical Mycology, 54, 478-491. doi: 10.1093/mmy/myv117

Schmid, J., Magee, P. T., Holland, B. R., Zhang, N., Cannon, R. D., & Magee, B. B. (2016). Last hope for the doomed? Thoughts on the importance of a parasexual cycle for the yeast Candida albicans. Current Genetics, 62(1), 81-85. doi: 10.1007/s00294-015-0516-8

Conference Contribution - Published proceedings: Abstract

Benic, G. Z., Farella, M., Biggs, P., Heng, N., Cannon, R., & Mei, L. (2016). Efficacy of oral probiotics in managing biofilm formation in patients wearing fixed orthodontic appliances: A triple-blind randomized placebocontrolled trial. Proceedings of the Sir John Walsh Research Institute Research Symposium. (pp. 18). Retrieved from http://www.otago.ac.nz/sjwri/news/otago621026

Itskovich, Y., Meikle, M., Milne, T., Farella, M., & Cannon, R. (2016). Engineering 3-D constructs of human bone matrix in a mechanically-active environment. Proceedings of the Sir John Walsh Research Institute Research Symposium. (pp. 17-18). Retrieved from http://www.otago.ac.nz/sjwri/news/otago621026

Madani, G., Lamping, E., Lee, H. J., & Cannon, R. D. (2016). Role of cysteine residues in Candida albicans Cdr1p efflux pump expression and function. Proceedings of the Sir John Walsh Research Institute Research Symposium. (pp. 12). Retrieved from http://www.otago.ac.nz/sjwri/news/otago621026

Conference Contribution - Verbal presentation and other Conference outputs

Madani, G., Lamping, E., Lee, H. J., & Cannon, R. (2016, November). Contribution of cysteine residues to Candida albicans Cdr1p multidrug efflux pump expression and function. Verbal presentation at the Joint Meeting of the New Zealand Microbiological Society (NZMS) and the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB), Christchurch, New Zealand.

Choo, K. H., Lee, H. J., Knight, N. J., Holmes, A. R., & Cannon, R. D. (2016, November). Multilocus sequence typing analysis of Candida albicans isolates colonising acrylic dentures. Verbal presentation at the Joint Meeting of the New Zealand Microbiological Society (NZMS) and the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB), Christchurch, New Zealand.

Cannon, R. (2016, June). Antimicrobial resistance of fungi in oral microbiota. Verbal presentation at the 94th General Session of the International Association of Dental Research (IADR), Seoul, Republic of Korea.

2015

Journal - Research Article

Bennani, V., Hwang, L., Tawse-Smith, A., Dias, G. J., & Cannon, R. D. (2015). Effect of air-polishing on titanium surfaces, biofilm removal, and biocompatibility: A pilot study. BioMed Research International, 2015, 491047. doi: 10.1155/2015/491047

Keniya, M. V., Fleischer, E., Klinger, A., Cannon, R. D., & Monk, B. C. (2015). Inhibitors of the Candida albicans Major Facilitator Superfamily transporter Mdr1p responsible for fluconazole resistance. PLoS ONE, e0126350. doi: 10.1371/journal.pone.0126350

Zhang, N., Magee, B. B., Magee, P. T., Holland, B. R., Rodrigues, E., Holmes, A. R., Cannon, R. D., & Schmid, J. (2015). Selective advantages of a parasexual cycle for the yeast Candida albicans. Genetics, 200(4), 1117-1132. doi: 10.1534/genetics.115.177170

Cannon, R. D., & Holmes, A. R. (2015). Learning the ABC of oral fungal drug resistance [Invited review]. Molecular Oral Microbiology, 30(6), 425-437. doi: 10.1111/omi.12109

Bakri, M. M., Rich, A. M., Cannon, R. D., & Holmes, A. R. (2015). In vitro expression of Candida albicans alcohol dehydrogenase genes involved in acetaldehyde metabolism. Molecular Oral Microbiology, 30(1), 27-38. doi: 10.1111/omi.12064

Conference Contribution - Published proceedings: Abstract

Cannon, R. D., Niimi, K., Harding, D. R. K., Holmes, A. R., Niimi, M., Monk, B. C., & Lamping, E. (2015). Understanding and overcoming antifungal drug resistance [Invited speaker]. Proceedings of the Australasian Mycological Society Scientific Meeting held jointly with the Australian Society for Microbiology Scientific Meeting. Retrieved from https://www.australasianmycologicalsociety.com

Lee, J., Lamping, E., Cannon, R., & Lee, H. (2015). Extracellular cysteines of Candida albicans Cdr1p affect its efflux-pump function. Journal of Dental Research, 94(Spec Iss B), 2343753. Retrieved from http://www.iadr.org/

Cannon, R., Lee, H., & Lamping, E. (2015). Overcoming antifungal drug resistance: A new target. Journal of Dental Research, 94(Spec Iss B), 2334952. Retrieved from http://www.iadr.org/

Al-Dujaili, M., Farella, M., Milne, T., & Cannon, R. (2015). Growth factor expression in the rat condyle. Journal of Dental Research, 94(Spec Iss B), 2343962. Retrieved from http://www.iadr.org/

Keniya, M., Goffeau, A., Maass, D., Cannon, R., & Monk, B. (2015). Yeast-based screens for modulators of a multidrug resistance pathway. Yeast, 32(Suppl. 1), (pp. S182). doi: 10.1002/yea.3092

Cannon, R. D., Lee, H. J., & Lamping, E. (2015). Functional analysis of PDR ABC transporters from fungal pathogens of humans and plants. Proceedings of the New Zealand Microbiological Society (NZMS) 60th Conference. (pp. 27). Retrieved from http://www.nzmsconference.org.nz/

Hwang, L., Bennani, V., Tawse-Smith, A., Dias, G., & Cannon, R. (2015). Effect of air-polishing on titanium surfaces, biofilm removal and biocompatibility. Journal of Dental Research, 94(Spec Iss A), IAHATT0010. Retrieved from http://www.iadr.org/

2014

Journal - Research Article

Keniya, M. V., Holmes, A. R., Niimi, M., Lamping, E., Gillet, J.-P., Gottesman, M. M., & Cannon, R. D. (2014). Drug resistance is conferred on the model yeast Saccharomyces cerevisiae by expression of full-length melanoma-associated human ATP-binding cassette transporter ABCB5. Molecular Pharmaceutics, 11(10), 3452-3462. doi: 10.1021/mp500230b

Pei, Z., Wang, B., Zhang, F., Niu, Z., Shi, S., Cannon, R. D., & Mei, L. (2014). Response of human periodontal ligament cells to baicalin. Journal of Periodontology, 85(9), 1283-1290. doi: 10.1902/jop.2014.130635

Bakri, M. M., Cannon, R. D., Holmes, A. R., & Rich, A. M. (2014). Detection of Candida albicans ADH1 and ADH2 mRNAs in human archival oral biopsy samples. Journal of Oral Pathology & Medicine, 43(9), 704-710. doi: 10.1111/jop.12193

Inger, M., Bennani, V., Farella, M., Bennani, F., & Cannon, R. D. (2014). Efficacy of air/water syringe tip sterilization. Australian Dental Journal, 59(1), 87-92. doi: 10.1111/adj.12146

Monk, B. C., Tomasiak, T. M., Keniya, M. V., Huschmann, F. U., Tyndall, J. D. A., O'Connell, III, J. D., Cannon, R. D., … Stroud, R. M. (2014). Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer. PNAS, 111(10), 3865-3870. doi: 10.1073/pnas.1324245111

Holmes, A. R., Rodrigues, E., van der Wielen, P., Lyons, K. M., Haigh, B. J., Wheeler, T. T., Dawes, P. J. D., & Cannon, R. D. (2014). Adherence of Candida albicans to silicone is promoted by the human salivary protein SPLUNC2/PSP/BPIFA2. Molecular Oral Microbiology, 29(2), 90-98. doi: 10.1111/mom.12048

Yuan, H., Li, J., Chen, L., Cheng, L., Cannon, R. D., & Mei, L. (2014). Esthetic comparison of white-spot lesion treatment modalities using spectrometry and fluorescence. Angle Orthodontist, 84(2), 343-349. doi: 10.2319/032113-232.1

Conference Contribution - Published proceedings: Abstract

Hou, L. X., Cannon, R. D., Lyons, K. M., & Holmes, A. R. (2014). Salivary protein profiles of xerostomia subjects and matched controls. Journal of Dental Research, 93(Spec Iss C). Retrieved from http://www.iadr.org

Mohamed Thani, W. S., MacFadyen, E., Rich, A. M., & Cannon, R. D. (2014). Fluconazole resistance against oral candida in patients taking antipsychotic drugs. Journal of Dental Research, 93(Spec Iss C). Retrieved from http://www.iadr.org

Hwang, L., Bennani, V., Tawse-Smith, A., Cannon, R. D., & Tompkins, G. R. (2014). Effect of air-polishing on titanium surfaces, biofilm removal and biocompatibility. Journal of Dental Research, 93(Spec Iss C). Retrieved from http://www.iadr.org

Sagatova, A., Keniya, M., Huschmann, F., Wilbanks, S., Cannon, R., Tyndall, J., & Monk, B. (2014). Triazole drug target structures in a resistant yeast strain. New Zealand Medical Journal, 127(1404). Retrieved from http://www.nzma.org.nz/journal

Mistry, D., Niimi, K., Niimi, M., & Cannon, R. D. (2014). Molecular analysis of Candida albicans ABC transporter Cdr1p. Journal of Dental Research, 93(Spec Iss B), 850. Retrieved from http://www.iadr.org

Tyndall, J. D. A., Sagatova, A., Tomasiak, T. M., Keniya, M. V., Huschmann, F. U., O'Connell, III, J. D., … Cannon, R. D., … Monk, B. C. (2014). Structures of full-length bitopic membrane protein CYP51 from Saccharomyces cerevisiae provide insight into substrate and drug binding and mutations affecting antifungal susceptibility. Proceedings of the CRYSTAL29: 29th Biennial Conference of the Society of Crystallographers in Australia and New Zealand (SCANZ). (pp. 50). Retrieved from http://www.crystal29.com/

Conference Contribution - Poster Presentation (not in published proceedings)

Sagatova, A., Keniya, M. V., Huschmann, F. U., Wilbanks, S. M., Cannon, R. D., Tyndall, J. D. A., & Monk, B. C. (2014, May). Egr11p structure in triazole resistant and susceptible strains of yeast. Poster session presented at the International Association for Dental Research (IADR) New Zealand Section Student Poster Competition, Dunedin, New Zealand.

Hwang, L., Bennani, V., Tawse-Smith, A., Cannon, R., Tompkins, G., & Dias, G. (2014, July). Effect of air-polishing treatment on titanium surfaces: An in vitro study. Poster session presented at the Sir John Walsh Research Institute Research Day, Dunedin, New Zealand.

Hwang, L., Bennani, V., Tawse-Smith, A., Cannon, R., Tompkins, G., & Dias, G. (2014, May). Effect of air-polishing treatment on titanium surfaces: An in vitro study. Poster session presented at the International Association for Dental Research (IADR) New Zealand Section Student Poster Competition, Dunedin, New Zealand.

Sagatova, A., Keniya, M., Huschmann, F., Wilbanks, S., Cannon, R., Tyndall, J., & Monk, B. (2014, September). Erg11p structure in a triazole resistant yeast strain. Poster session presented at the Division of Health Sciences Research Forum: Learning Different Research Languages, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Lee, H. J., Lamping, E., & Cannon, R. D. (2014, November). Unravelling the importance of conserved extracellular loop motifs of the archetype fungal multidrug efflux pump Candida albicans Cdr1p. Verbal presentation at the Joint Meeting of the New Zealand Microbiological Society (NZMS) and the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB), Wellington, New Zealand.

Monk, B. C., Tomasiak, T. M., Cannon, R. D., Sagatova, A., Keniya, M. V., Huschmann, F. U., Tyndall, J. D. A., … Stroud, R. M. (2014, November). A target structure to invigorate antifungal discovery. Verbal presentation at the Frontiers of Biology Satellite Meeting: From Protein Structure and Function to Drugs, Wellington, New Zealand.

Tyndall, J. D. A., Sagatova, A., Tomasiak, T. M., Keniya, M. V., Huschmann, F. U., O'Connell, III, J. D., … Cannon, R. D., … Monk, B. C. (2014, April). Structures of full-length bitopic membrane protein CYP51 from Saccharomyces cerevisiae provide insight into substrate and drug binding and mutations affecting antifungal susceptibility. Verbal presentation at the 29th Biennial Conference of the Society of Crystallographers in Australia and New Zealand (SCANZ), O'Reilly's Rainforest Retreat, Australia.

2013

Chapter in Book - Other

Cannon, R. D., & Firth, N. A. (2013). Fungi and fungal infections of the oral cavity. In R. J. Lamont, G. N. Hajishengallis & H. F. Jenkinson (Eds.), Oral microbiology and immunology. (2nd ed.) (pp. 343-360). Washington, DC: ASM Press. doi: 10.1128/9781555818906

Journal - Research Article

Lamping, E., Niimi, M., & Cannon, R. D. (2013). Small, synthetic, GC-rich mRNA stem-loop modules 5' proximal to the AUG start-codon predictably tune gene expression in yeast. Microbial Cell Factories, 12, 74. doi: 10.1186/1475-2859-12-74

Rawal, M. K., Khan, M. F., Kapoor, K., Goyal, N., Sen, S., Saxena, A. K., … Tyndall, J. D. A., Monk, B. C., Cannon, R. D., … Prasad, R. (2013). Insight into pleiotropic drug resistance ATP-binding cassette pump drug transport through mutagenesis of Cdr1p transmembrane domains. Journal of Biological Chemistry, 288(34), 24480-24493. doi: 10.1074/jbc.M113.488353

Han, T.-L., Tumanov, S., Cannon, R. D., & Villas-Boas, S. G. (2013). Metabolic response of Candida albicans to phenylethyl alcohol under hyphae-inducing conditions. PLoS ONE, 8(8), e71364. doi: 10.1371/journal.pone.0071364

Keniya, M. V., Cannon, R. D., Nguyễn, Ấ., Tyndall, J. D. A., & Monk, B. C. (2013). Heterologous expression of Candida albicans Pma1p in Saccharomyces cerevisiae. FEMS Yeast Research, 13(3), 302-311. doi: 10.1111/1567-1364.12035

Weerasekera, M. M., Sissons, C. H., Wong, L., Anderson, S., Holmes, A. R., & Cannon, R. D. (2013). Use of denaturing gradient gel electrophoresis for the identification of mixed oral yeasts in human saliva. Journal of Medical Microbiology, 62, 319-330. doi: 10.1099/jmm.0.050237-0

Conference Contribution - Published proceedings: Abstract

Huschmann, F. U., Tomasiak, T. M., Keniya, M. V., O'Connell, III, J. D., Luckner, S. R., Krause, K., Cannon, R. D., … Tyndall, J. D. A., & Monk, B. C. (2013). Antifungal drug discovery: Crystallization of the cytochrome P450 triazole target. Proceedings of the Australasian Pharmaceutical Science Association (APSA) Conference. Retrieved from http://apsa-online.org/home.html

Huschmann, F. U., Tomasiak, T. M., Keniya, M. V., O'Connell, III, J. D., Luckner, S. R., Krause, K., Cannon, R. D., … Tyndall, J. D. A., & Monk, B. C. (2013). Crystallization of Erg11p: The cytochrome P450 target of triazole antifungals. Acta Crystallographica Section A, A69, (pp. s64). [Abstract]

Cannon, R., Niimi, K., Lamping, E., Huschmann, F. U., Niimi, M., Keniya, M. V., Tyndall, J. D. A., Holmes, A. R., & Monk, B. C. (2013). Overcoming antifungal drug resistance. Proceedings of the Sir John Walsh Research Institute Research Day. (pp. 6). Retrieved from http://sjwri.otago.ac.nz/research/sjwri/

Conference Contribution - Poster Presentation (not in published proceedings)

Keniya, M. V., Fleischer, E., Klinger, A., Cannon, R. D., & Monk, B. C. (2013, September). Expression of MDR proteins in yeast for structure-function studies and drug discovery. Poster session presented at the Role of Multidrug Resistance Proteins in Pharmacokinetics and Toxicology Conference, Ryn, Poland.

Monk, B. C., Tomasiak, T. M., Keniya, M. V., Cannon, R. D., Huschmann, F. U., Tyndall, J. D. A., … Stroud, R. M. (2013, August). Crystal structures of full-length Saccharomyces cerevisiae Erg11p give insight into triazole and substrate binding. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Cannon, R. (2013, July). Overcoming antifungal drug resistance. Keynote presentation at the Sir John Walsh Research Institute Research Day, Dunedin, New Zealand.

2012

Chapter in Book - Research

Monk, B. C., Niimi, K., Holmes, A. R., Strouse, J. J., Sklar, L. A., & Cannon, R. D. (2012). Fungal efflux-mediated resistance: From targets to inhibitors. In G. Tegos & E. Mylonakis (Eds.), Antimicrobial drug discovery: Emerging strategies. (pp. 77-88). Oxford, UK: CABI.

Journal - Research Article

Han, T.-L., Cannon, R. D., & Villas-Bôas, S. G. (2012). Metabolome analysis during the morphological transition of Candida albicans. Metabolomics, 8(6), 1204-1217. doi: 10.1007/s11306-012-0416-6

Han, T.-L., Cannon, R. D., & Villas-Bôas, S. G. (2012). The metabolic response of Candida albicans to farnesol under hyphae-inducing conditions. FEMS Yeast Research, 12(8), 879-889. doi: 10.1111/j.1567-1364.2012.00837.x

Hayama, K., Ishibashi, H., Ishijima, S. A., Niimi, K., Tansho, S., Ono, Y., Monk, B. C., Holmes, A. R., … Cannon, R. D., & Abe, S. (2012). A D-octapeptide drug efflux pump inhibitor acts synergistically with azoles in a murine oral candidiasis infection model. FEMS Microbiology Letters, 328(2), 130-137. doi: 10.1111/j.1574-6968.2011.02490.x

Niimi, K., Harding, D. R. K., Holmes, A. R., Lamping, E., Niimi, M., Tyndall, J. D. A., Cannon, R. D., & Monk, B. C. (2012). Specific interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a D-octapeptide derivative inhibitor. Molecular Microbiology, 85(4), 747-767. doi: 10.1111/j.1365-2958.2012.08140.x

Niimi, K., Woods, M. A., Maki, K., Nakayama, H., Hatakenaka, K., Chibana, H., … Niimi, M., Cannon, R. D., & Monk, B. C. (2012). Reconstitution of high-level micafungin resistance detected in a clinical isolate of Candida glabrata identifies functional homozygosity in glucan synthase gene expression. Journal of Antimicrobial Chemotherapy, 67(7), 1666-1676. doi: 10.1093/jac/dks112

Holmes, A. R., Chong, K., Rodrigues, E., Cannon, R. D., Carpenter, E., Ruske, D. R., & Dawes, P. J. D. (2012). Yeast colonization of voice prostheses: Pilot study investigating effect of a bovine milk product containing anti-Candida albicans immunoglobulin A antibodies on yeast colonization and valve leakage. Annals of Otology, Rhinology & Laryngology, 121(1), 61-66. doi: 10.1177/000348941212100111

Ishijima, S. A., Hayama, K., Takahashi, M., Holmes, A. R., Cannon, R. D., & Abe, S. (2012). N-acetylglucosamine increases symptoms and fungal burden in a murine model of oral candidiasis. Medical Mycology, 50(3), 252-258. doi: 10.3109/13693786.2011.598194

Journal - Professional & Other Non-Research Articles

Cannon, R., Knight, N., Bennani, V., & Lyons, K. (2012). Colonisation of acrylic denture fitting surfaces by candida species. New Zealand Dental Association News, (December), 52.

Conference Contribution - Published proceedings: Abstract

Tasmania, L., Love, R., & Cannon, R. (2012). Contact guidance of endodontic pathogens on mirco-grooved polymethylmethacrylate discs. New Zealand Dental Journal, 108(4), (pp. 151). [Abstract]

Hou, L. L., Holmes, A., Nolan, A., Lyons, K., & Cannon, R. (2012). Oral yeast carriage and saliva protein patterns of xerostomia subjects and matched controls. New Zealand Dental Journal, 108(4), (pp. 149). [Abstract]

Schmid, J., Wilkins, M., Zhang, N., Bradshaw, R., Cox, M., Cannon, R., & Schardl, C. (2012). Why do so many fungal open reading frames contain repeats? Mycoses, 55(Suppl. 4), (pp. 67-68). doi: 10.1111/j.1439-0507.2012.02205.x

Niimi, M., Tanabe, K., Niimi, K., Lamping, E., Nagi, M., Holmes, A. R., Keniya, M. V., Monk, B. C., & Cannon, R. D. (2012). Milbemycins are broad-spectrum fungal multidrug efflux pump inhibitors that interact directly with the transmembrane domains of Candida albicans Cdr1p and Cdr2p. Mycoses, 55(Suppl. 4), (pp. 130). doi: 10.1111/j.1439-0507.2012.02206.x

Niimi, K., Lamping, E., Niimi, M., & Cannon, R. D. (2012). Dissection of C-albicans ABC transporter Cdr1p: Large intracellular and extracellular loops are critical structural and functional elements. Mycoses, 55(Suppl. 4), (pp. 335). doi: 10.1111/j.1439-0507.2012.02206.x

Han, T.-L., Villas-Bôas, S. G., & Cannon, R. D. (2012). Down-regulation of central carbon metabolism during the morphological transition of Candida albicans. Mycoses, 55(Suppl. 4), (pp. 65-66). doi: 10.1111/j.1439-0507.2012.02205.x

Conference Contribution - Poster Presentation (not in published proceedings)

Tomasiak, T. M., Monk, B. C., Keniya, M. V., Huschmann, F. U., Tyndall, J. D. A., O'Connell, III, J. D., Cannon, R. D., … Stroud, R. M. (2012, November). Structure of a full-length bitopic single membrane spanning cytochrome p450: The antifungal target lanosterol 14-alpha demethylase. Poster session presented at the 4th Membrane Protein Technologies Meeting: NIH Roadmap to Membrane Protein Structures and Complexes, San Francisco, CA.

Huschmann, F., Monk, B. C., Cannon, R. D., & Tyndall, J. D. A. (2012, August). Overcoming resistance in fungal pathogens: Towards crystallization of the azole target from Candida albicans. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Monk, B. C., Tomasiak, T. M., Keniya, M. V., Huschmann, F. U., Tyndall, J. D. A., O'Connell, III, J. D., Cannon, R. D., … Stroud, R. M. (2012, November). A cytochrome P450 monospanner in the works: Structure of full-length yeast lanosterol 14α-demethylase. Verbal presentation at the 4th Membrane Protein Technologies Meeting: NIH Roadmap to Membrane Protein Structures and Complexes, San Francisco, CA.

2011

Journal - Research Article

Holmes, A. R., Keniya, M. V., Ivnitski-Steele, I., Monk, B. C., Lamping, E., Sklar, L. A., & Cannon, R. D. (2011). The monoamine oxidase A inhibitor clorgyline is a broad-spectrum inhibitor of fungal ABC and MFS transporter efflux pump activities which reverses the azole resistance of Candida albicans and Candida glabrata clinical isolates. Antimicrobial Agents & Chemotherapy, 56(3), 1508-1515. doi: 10.1128/aac.05706-11

Tanabe, K., Lamping, E., Nagi, M., Okawada, A., Holmes, A. R., Miyazaki, Y., Cannon, R. D., Monk, B. C., & Niimi, M. (2011). Chimeras of Candida albicans Cdr1p and Cdr2p reveal features of pleiotropic drug resistance transporter structure and function. Molecular Microbiology, 82(2), 416-433. doi: 10.1111/j.1365-2958.2011.07820.x

Han, T.-L., Cannon, R. D., & Villas-Bôas, S. G. (2011). The metabolic basis of Candida albicans morphogenesis and quorum sensing. Fungal Genetics & Biology, 48(8), 747-763. doi: 10.1016/j.fgb.2011.04.002

Conference Contribution - Published proceedings: Abstract

Cannon, R. D., Niimi, K., Lamping, E., Niimi, M., Holmes, A. R., & Monk, B. C. (2011). Understanding the inhibition of fungal drug efflux pumps. Journal of Dental Research, 90(Spec Iss B), 154838. Retrieved from http://www.dentalresearch.org

Holmes, A., Keniya, M. V., Niimi, M., & Cannon, R. D. (2011). Melanomas are notoriously drug-resistant. New Zealand Melanoma Summit. Retrieved from http://www.melanoma.org.nz/MelNet/News/Melanoma-Summit-2011/Abstracts-innovations-and-models-of-best-practice-in-New-Zealand/

Conference Contribution - Verbal presentation and other Conference outputs

Schmid, J., Wilkins, M., Zhang, N., Cox, M., Cannon, R., & Schardl, C. (2011, November). Biological function of DNA repeats in fungal open reading frames. Verbal presentation at the New Zealand Microbiological Society Conference, Palmerston North, New Zealand.

Zhang, N., Magee, B. B., Magee, P. T., Holland, B. R., Rodrigues, E., Holmes, A. R., Cannon, R. D., & Schmid, J. (2011, November). Sex has no obvious net benefit for Candida albicans. Verbal presentation at the New Zealand Microbiological Society Conference, Palmerston North, New Zealand.

Cannon, R. D., Ivnitski-Steele, I., Monk, B. C., Sklar, L. A., & Holmes, A. R. (2011, November). Overcoming drug resistance in oral yeast. Keynote presentation at the New Zealand Microbiological Society Conference, Palmerston North, New Zealand.

2010

Chapter in Book - Research

Cannon, R. D., Lyons, K. M., Chong, K., & Holmes, A. R. (2010). Adhesion of yeast and bacteria to oral surfaces. In G. J. Seymour, M. P. Cullinan & N. C. K. Heng (Eds.), Oral Biology. (pp. 103-124). New York: Springer. doi: 10.1007/978-1-60761-820-1_8

Lamping, E., & Cannon, R. D. (2010). Use of a yeast-based membrane protein expression technology to overexpress drug resistance efflux pumps. In G. J. Seymour, M. P. Cullinan & N. C. K. Heng (Eds.), Oral Biology. (pp. 219-250). New York: Springer. doi: 10.1007/978-1-60761-820-1_15

Journal - Research Article

Mohd Bakri, M., Hussaini, H. M., Holmes, A. R., Cannon, R. D., & Rich, A. M. (2010). Revisiting the association between candidal infection and carcinoma, particularly oral squamous cell carcinoma. Journal of Oral Microbiology, 2, 5780. doi: 10.3402/jom.v2i0.5780

Niimi, K., Monk, B. C., Hirai, A., Hatakenaka, K., Umeyama, T., Lamping, E., … Cannon, R. D., & Niimi, M. (2010). Clinically significant micafungin resistance in Candida albicans involves modification of a glucan synthase catalytic subunit GSC1 (FKS1) allele followed by loss of heterozygosity. Journal of Antimicrobial Chemotherapy, 65, 842-852. doi: 10.1093/jac/dkq073

Zhang, N., Cannon, R. D., Holland, B. R., Patchett, M. L., & Schmid, J. (2010). Impact of genetic background on allele selection in a highly mutable Candida albicans gene, PNG2. PLoS ONE, 5(3), e9614. doi: 10.1371/journal.pone.0009614

Niimi, M., Firth, N. A., & Cannon, R. D. (2010). Antifungal drug resistance of oral fungi. Odontology, 98(1), 15-25. doi: 10.1007/s10266-009-0118-3

Lamping, E., Baret, P. V., Holmes, A. R., Monk, B. C., Goffeau, A., & Cannon, R. D. (2010). Fungal PDR transporters: Phylogeny, topology, motifs and function. Fungal Genetics & Biology, 47(2), 127-142. doi: 10.1016/j.fgb.2009.10.007

Conference Contribution - Published proceedings: Abstract

Cannon, R., Niimi, K., Woods, M., Hirai, A., Umeyama, T., Hatakenaka, K., … Lamping, E., Niimi, M., & Monk, B. (2010). Echinocandin resistance in Candida species. Journal of Dental Research, 89(Spec Iss C). Retrieved from http://www.dentalresearch.org

Conference Contribution - Poster Presentation (not in published proceedings)

Holmes, A. R., Niimi, M., Lamping, E., Keniya, M. V., Niimi, K., Monk, B. C., & Cannon, R. D. (2010, February-March). Enhancing functional heterologous expression of human ABCB1 in Saccharomyces cerevisiae. Poster session presented at the 3rd FEBS Special Meeting: ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases, Innsbruck, Austria.

Conference Contribution - Verbal presentation and other Conference outputs

Cannon, R., Hayama, K., Lamping, E., Niimi, K., Keniya, M., Niimi, M., Holmes, A., … Monk, B. (2010, September). Drug discovery using fungal ABC transporters expressed in Saccharomyces cerevisiae. Verbal presentation at the 28th Small Meeting on Yeast Transport and Energetics (SMYTE), New Delhi, India.

2009

Journal - Research Article

Rodrigues, E., Chong, K., Holmes, A. R., Cannon, R. D., Ruske, D. R., & Dawes, P. J. D. (2009). An in-vitro device for the assessment of biofilm mediated voice prosthesis damage: How we do it [Letter to the editor]. Clinical Otolaryngology, 34(5), 481-484. doi: 10.1111/j.1749-4486.2009.01996.x

Ivnitski-Steele, I., Holmes, A. R., Lamping, E., Monk, B. C., Cannon, R. D., & Sklar, L. A. (2009). Identification of Nile red as a fluorescent substrate of the Candida albicans ATP-binding cassette transporters Cdr1p and Cdr2p and the major facilitator superfamily transporter Mdr1p. Analytical Biochemistry, 394(1), 87-91. doi: 10.1016/j.ab.2009.07.001

Zhang, N., Upritchard, J. E., Holland, B. R., Fenton, L. E., Ferguson, M. M., Cannon, R. D., & Schmid, J. (2009). Distribution of mutations distinguishing the most prevalent disease-causing Candida albicans genotype from other genotypes. Infection, Genetics & Evolution, 9(4), 493-500. doi: 10.1016/j.meegid.2009.01.007

Lamping, E., Ranchod, A., Nakamura, K., Tyndall, J. D. A., Niimi, K., Holmes, A. R., Niimi, M., & Cannon, R. D. (2009). Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei. Antimicrobial Agents & Chemotherapy, 53(2), 354-369. doi: 10.1128/AAC.01095-08

Cannon, R. D., Lamping, E., Holmes, A. R., Niimi, K., Baret, P. V., Keniya, M. V., … Niimi, M., … Monk, B. C. (2009). Efflux-mediated antifungal drug resistance. Clinical Microbiology Reviews, 22(2), 291-321. doi: 10.1128/cmr.00051-08

Conference Contribution - Published proceedings: Abstract

Mohd Bakri, M., Horne, L., Fisher, M., Holmes, A. R., Cannon, R. D., & Rich, A. M. (2009). Role of Candida albicans in pre-cancerous oral lesions. Journal of Dental Research, 88(Spec Iss A), 3077. Retrieved from http://www.dentalresearch.org

Keniya, M., Holmes, A., Niimi, M., Cannon, R., & Monk, B. (2009). Heterologous expression of the Candida albicans plasma membrane proton pump in Saccharomyces cerevisiae. Proceedings of the Third Federation of European Biochemical Societies Advanced Lecture Course: Human Fungal Pathogens: Molecular Mechanisms of Host-Pathogen Interactions and Virulence. (pp. 137). FEBS. Retrieved from http://www.pasteur.fr/infosci/conf/hfp2009/

Han, T. L., Cannon, R. D., & Villas-Bôas, S. G. (2009). Elucidation of metabolic pathways governing Candida albicans morphogenesis using metabolomics. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]

Zhang, N., Magee, B. B., Magee, P. T., Holland, B. R., Cannon, R. D., & Schmid, J. (2009). Most clinical isolates of the pathogenic fungus Candida albicans can mate and generate viable recombinants, as assessed using a new two-marker selection system. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]

Schmid, J., Zhang, N., Cannon, R. D., Holland, B. R., & Patchett, M. L. (2009). Impact of genetic background on allele section in the highly mutable Candida albicans PNG2. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]

Rodrigues, E., Yang, D., Zhang, N., Magee, B. B., Magee, P. T., Holmes, A. R., … Cannon, R. D. (2009). Mating of Candida albicans in an in vivo model of oral colonisation. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]

Cannon, R. D., Lamping, E., Niimi, K., Holmes, A. R., Monk, B. C., & Niimi, M. (2009). Functional expression of human ABCB1 in Saccharomyces cerevisiae. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]

Lamping, E., Baret, P. V., Holmes, A. R., Monk, B. C., Goffeau, A., & Cannon, R. D. (2009). Phylogenetic clustering and new motifs of fungal PDR ABC transporters. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]

Han, T.-L., Cannon, R. D., & Villas-Boas, S. G. (2009). Metabolome analysis of Candida albicans during morphogenesis. New Biotechnology. 25(Suppl. 1), (pp. S363). [Abstract]

Conference Contribution - Verbal presentation and other Conference outputs

Cannon, R. D., Lamping, E., Keniya, M. V., Niimi, K., Tanabe, K., Niimi, M., Monk, B. C., & Holmes, A. R. (2009, May). Azole resistance in Candida species. Verbal presentation at the 17th Congress of the International Society for Human and Animal Mycology (ISHAM): Medical Mycology in the 21st Century: Scientific Base and Anticipated Challenges, Tokyo, Japan.

2008

Journal - Research Article

Holmes, A. R., Lin, Y.-H., Niimi, K., Lamping, E., Keniya, M., Niimi, M., … Monk, B. C., & Cannon, R. D. (2008). ABC transporter Cdr1p contributes more than Cdr2p does to fluconazole efflux in fluconazole-resistant Candida albicans clinical isolates. Antimicrobial Agents & Chemotherapy, 52(11), 3851-3862. doi: 10.1128/AAC.00463-08

Deng, D., Lauren, D. R., Cooney, J. M., Jensen, D. J., Wurms, K. V., Upritchard, J. E., Cannon, R. D., … Li, M. Z. (2008). Antifungal saponins from Paris polyphylla Smith. Planta Medica, 74(11), 1397-1402. doi: 10.1055/s-2008-1081345

Conference Contribution - Published proceedings: Abstract

Young, C., Holmes, A., Cannon, R. D., & Monk, B. C. (2008). Modifying a yeast growth medium for recombinant protein research. Journal of Dental Research, 87(Spec Iss C). Retrieved from http://www.dentalresearch.org

Bakri, M., Horne, L., Fisher, M., Holmes, A. R., Cannon, R. D., & Rich, A. (2008). Role of Candida albicans in pre-cancerous oral lesions. Proceedings of the Faculty of Dentistry 3M Research Day. Retrieved from http://dentistry.otago.ac.nz/research/rd2008/presentations.html

Raju, S., Holmes, A., Lamping, E., Monk, B., & Cannon, R. (2008). Functional analysis of phosphorylation sites in Candida albicans Cdr1p. Journal of Dental Research, 87(Spec Iss B), 3023. Retrieved from http://www.dentalresearch.org

Han, T., Ambrose, M., Cannon, R., & Villas-Bôas, S. G. (2008). The metabolic basis of Candida albicans morphogenesis and the potential of metabolomics to unravel its mechanism. Proceedings of the New Zealand Microbiological Society Microbiology Conference. (pp. 24). NZMS. Retrieved from http://www.nzmsconference08.org.nz/files/Poster-Abstracts-NZMS-2008.pdf

Kajiwara, S., Honda, T., Oura, T., Lamping, E., Keniya, M. V., Niimi, K., Niimi, M., Holmes, A. R., Monk, B. C., & Cannon, R. D. (2008). Alteration of Saccharomyces cerevisiae membrane composition for improved heterologous expression of human transporter ABCB1. Proceedings of the New Zealand Microbiological Society Microbiology Conference. (pp. 21). NZMS. Retrieved from http://www.nzmsconference08.org.nz/files/Poster-Abstracts-NZMS-2008.pdf

Chong, K., Rodrigues, E., Holmes, A. R., Cannon, R. D., Hodgkinson, A. J., Carpenter, L., Ruske, D., & Dawes, P. (2008). Overcoming Candida albicans adherence to silicone and the leakage of voice prosthesis valves. Proceedings of the New Zealand Microbiological Society Microbiology Conference. (pp. 52). NZMS. Retrieved from http://www.nzmsconference08.org.nz/files/Oral-Abstracts-NZMS-2008.pdf

Holmes, A. R., Raju, S., Uwamahoro, N., Niimi, K., Lamping, E., Keniya, M. V., Monk, B. C., & Cannon, R. D. (2008). Phosphorylation site S312 is important for Candida albicans Cdr1p function. Proceedings of the New Zealand Microbiological Society Microbiology Conference. (pp. 18-19). NZMS. Retrieved from http://www.nzmsconference08.org.nz/files/Oral-Abstracts-NZMS-2008.pdf

Zhang, N., Magee, B., Magee, P., Cannon, R., & Schmid, J. (2008). Development of a new marker system for efficient selection of sexual recombinants between clinical Candida albicans isolates. Proceedings of the 9th American Society for Microbiology Conference on Candida and Candidiasis. (pp. 79). Washington, DC: ASM. [Abstract]

Keniya, M. V., Holmes, A. R., Niimi, M., Cannon, R. D., & Monk, B. C. (2008). Heterologous expression of the Candida albicans plasma membrane proton pump in Saccharomyces cerevisiae. Proceedings of the 9th American Society for Microbiology Conference on Candida and Candidiasis. (pp. 83). Washington, DC: ASM. [Abstract]

Niimi, M., Tanabe, K., Niimi, K., Lamping, E., Takano, Y., Holmes, A. R., Monk, B. C., Cannon, R. D., & Uehara, Y. (2008). Characterization of drug efflux pump inhibitors that chemosensitize fungal ABC transporters. Proceedings of the 9th American Society for Microbiology Conference on Candida and Candidiasis. (pp. 50). Washington, DC: ASM. [Abstract]

Niimi, K., Monk, B. C., Maki, K., Hatakenaka, K., Ikeda, F., Niimi, M., … Cannon, R. D. (2008). Clinically significant micafungin resistance in Candida glabrata requires mutations in both FKS1 and FKS2. Proceedings of the 9th American Society for Microbiology Conference on Candida and Candidiasis. (pp. 24). Washington, DC: ASM. [Abstract]

Weerasekera, M. M., Cannon, R. D., Anderson, S. A., Holmes, A. R., Wong, L., & Sissons, C. H. (2008). Application of PCR-DGGE to identify yeast populations in oral ecosystems. Proceedings of the 12th International Symposium on Microbial Ecology. ISME. Retrieved from http://www.kenes.com/isme12/posters/1385.htm

Conference Contribution - Poster Presentation (not in published proceedings)

Lamping, E., Nakamura, K., Tanabe, K., Niimi, K., Holmes, A. R., Takano, Y., … Cannon, R. D., & Niimi, M. (2008, September). Cryptococcus neoformans AFR2 and MDR1 are ABC-type multidrug efflux transporters able to pump azoles and many other xenobiotics. Poster session presented at the 7th International Conference on Cryptococcus & Cryptococcosis, Nagasaki, Japan.

Bakri, M., Horne, L., Fisher, M., Holmes, A. R., Cannon, R. D., & Rich, A. (2008, October). Role of Candida albicans in pre-cancerous oral lesions. Poster session presented at the 48th Annual Meeting of the Australia-New Zealand Division of the International Association for Dental Research, Perth, Western Australia.

Conference Contribution - Verbal presentation and other Conference outputs

Lamping, E., Niimi, K., Monk, B. C., Holmes, A. R., Niimi, M., & Cannon, R. D. (2008, March-April). Yeast: A promising host for the study of eukaryotic membrane proteins. Plenary presentation at the 2nd International Symposium on Advanced Biological Engineering and Science, Beijing, China.

2007

Journal - Research Article

Cannon, R. (2007). The Sir John Walsh Research Institute: A national institute for oral health research in New Zealand. New Zealand Dental Journal, 103(1), 17.

Hodgkinson, A. J., Cannon, R. D., Holmes, A. R., Fischer, F. J., & Willix-Payne, D. J. (2007). Production from dairy cows of semi-industrial quantities of milk-protein concentrate (MPC) containing efficacious anti-Candida albicans IgA antibodies. Journal of Dairy Research, 74, 269-275.

Lamping, E., Monk, B. C., Niimi, K., Holmes, A. R., Tsao, S., Tanabe, K., Niimi, M., … Cannon, R. D. (2007). Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae. Eukaryotic Cell, 6(7), 1150-1165.

Cannon, R. D., Lamping, E., Holmes, A. R., Niimi, K., Tanabe, K., & Monk, B. C. (2007). Candida albicans drug resistance: Another way to cope with stress. Microbiology, 153, 3211-3217.

Conference Contribution - Published proceedings: Abstract

Raju, S., Holmes, A. R., & Cannon, R. D. (2007). Functional analysis of phosphorylation sites in Candida albicans Cdr1p. Proceedings of the Faculty of Dentistry 3M Research Day. Retrieved from http://dentistry.otago.ac.nz/research/rd2007/presentations.html

Rodrigues, E., Holmes, A. R., Dawes, P. J. D., Haigh, B., & Cannon, R. D. (2007). Parotid salivary protein promotes adherence of Candida albicans to silicone rubber. Proceedings of the Faculty of Dentistry 3M Research Day. Retrieved from http://dentistry.otago.ac.nz/research/rd2007/presentations.html

Niimi, K., Maki, K., Hatakenaka, K., Ishikawa, T., Takata, T., Tamura, K., Niimi, M., … Monk, B. C., & Cannon, R. D. (2007). Clinical micafungin resistance requires functional homozygosity in Candida glabrata glucan synthase. Japanese Journal of Medical Mycology. 48(Suppl. 1), (pp. 69). [Abstract]

Raju, S., Holmes, A. R., & Cannon, R. D. (2007). Functional analysis of phosphorylation sites in Candida albicans drug efflux pump Cdr1p. New Zealand Medical Journal, 120(1255). Retrieved from http://journal.nzma.org.nz/journal/120-1255/2574/content.pdf

Raju, S., Holmes, A. R., Lamping, E., Monk, B. C., & Cannon, R. D. (2007). Functional analysis of phosphorylation sites in Candida albicans Cdr1p. Journal of Dental Research, 86(Spec Iss B). Retrieved from http://www.dentalresearch.org

Holmes, A. R., Lin, Y.-H., Niimi, K., Lamping, E., Monk, B. C., Keniya, M., & Cannon, R. D. (2007). Differential expression and activities of drug efflux proteins Cdr1p and Cdr2p in azole resistant Candida albicans isolates. Proceedings of the Faculty of Dentistry 3M Research Day. Retrieved from http://dentistry.otago.ac.nz/research/rd2007/presentations.html

Lamping, E., Nakamura, K., Ranchod, A., Holmes, A. R., Niimi, K., Niimi, M., & Cannon, R. D. (2007). Mechanisms of innate azole resistance in Candida krusei. Proceedings of the Faculty of Dentistry 3M Research Day. Retrieved from http://dentistry.otago.ac.nz/research/rd2007/presentations.html

Niimi, K., Monk, B. C., Lamping, E., Holmes, A. R., Niimi, M., Maki, K., & Cannon, R. D. (2007). Echinocandin resistance mechanisms in Candida species. Proceedings of the Faculty of Dentistry 3M Research Day. Retrieved from http://dentistry.otago.ac.nz/research/rd2007/presentations.html

Cannon, R. D., Niimi, K., Holmes, A. R., Lamping, E., Keniya, M., Niimi, M., & Monk, B. C. (2007). Overcoming efflux pump-mediated drug resistance in Candida albicans. Journal of Dental Research, 86(Spec Iss A), 0247. Retrieved from http://www.dentalresearch.org

Conference Contribution - Poster Presentation (not in published proceedings)

Keniya, M. V., Holmes, A. R., Cannon, R. D., & Monk, B. C. (2007, November). Heterologous expression of the Candida albicans plasma membrane proton pump in Saccharomyces cerevisiae. Poster session presented at the Joint New Zealand Microbiology Society and New Zealand Society for Biochemistry and Molecular Biology Annual Conference, Wellington, New Zealand.

Holmes, A., Lin, Y.-H., Niimi, K., Lamping, E., Monk, B., Keniya, M., & Cannon, R. (2007, May). Differential expression and activities of drug efflux proteins Cdr1p and Cdr2p in azole resistant Candida albicans isolates. Poster session presented at the Second Federation of European Biochemical Societies Advanced Lecture Course, La Colle sur Loup, France.

Conference Contribution - Verbal presentation and other Conference outputs

Bakri, M., Holmes, A. R., Cannon, R. D., & Rich, A. (2007, November). The Acetaldehyde Dehydrogenase (ADH) genes of Candida albicans. Verbal presentation at the Joint New Zealand Microbiology Society and New Zealand Society for Biochemistry and Molecular Biology Annual Conference, Wellington, New Zealand.

Rodrigues, E., Upritchard, J. E., Yang, D., Holmes, A. R., Schmid, J., Perlin, D. S., & Cannon, R. D. (2007, November). A new model for oral colonisation by Candida albicans. Verbal presentation at the Joint New Zealand Microbiology Society and New Zealand Society for Biochemistry and Molecular Biology Annual Conference, Wellington, New Zealand.

Cannon, R. D., Holmes, A. R., Lamping, E., Keniya, M. V., Niimi, K., & Monk, B. C. (2007, November). Overcoming Candida albicans drug resistance. Verbal presentation at the Joint New Zealand Microbiology Society and New Zealand Society for Biochemistry and Molecular Biology Annual Conference, Wellington, New Zealand.

Weerasekera, M. M., Wong, L., Anderson, S., Holmes, A. R., Cannon, R. D., & Sissons, C. H. (2007, November). Analysis of yeast species present in saliva by PCR-DGGE. Verbal presentation at the Joint New Zealand Microbiology Society and New Zealand Society for Biochemistry and Molecular Biology Annual Conference, Wellington, New Zealand.

2006

Chapter in Book - Other

Cannon, R. D., & Firth, N. A. (2006). Fungi and fungal infections of the oral cavity. In R. J. Lamont, R. A. Burne, M. S. Lantz & D. J. LeBlanc (Eds.), Oral microbiology and immunology. (pp. 333-348). Washington, DC: American Society for Microbiology.

Journal - Research Article

Niimi, K., Maki, K., Ikeda, F., Holmes, A. R., Lamping, E., Niimi, M., Monk, B. C., & Cannon, R. D. (2006). Overexpression of Candida albicans CDR1, CDR2, or MDR1 does not produce significant changes in echinocandin susceptibility. Antimicrobial Agents & Chemotherapy, 50(4), 1148-1155.

Holmes, A. R., Tsao, S., Ong, S.-W., Lamping, E., Niimi, K., Monk, B. C., Niimi, M., … Cannon, R. D. (2006). Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2. Molecular Microbiology, 62(1), 170-186.

Holmes, A. R., van der Wielen, P., Cannon, R. D., Ruske, D., & Dawes, P. (2006). Candida albicans binds to saliva proteins selectively adsorbed to silicone. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology, 102(4), 488-494.

Journal - Research Other

Cannon, R. D., & Tompkins, G. R. (2006). Improving the effectiveness of chlorhexidine. New Zealand Dental Journal, 102(1), 17.

Holmes, A. R., Tsao, S., Lamping, E., Niimi, K., Monk, B. C., Tanabe, K., Niimi, M., & Cannon, R. D. (2006). Amino acid residues affecting drug pump function in Candida albicans: C. albicans drug pump function [Review]. Nippon Ishinkin Gakkai Zasshi, 47(4), 275-281.

Conference Contribution - Published proceedings: Abstract

Lyons, K. M., Cannon, R. D., Holmes, A. R., & Love, R. M. (2006). Microbial adhesion to prosthetic materials used to restore maxillary defects. Journal of Dental Research, 85(Spec Iss B), 1376. Retrieved from http://www.dentalresearch.org

Niimi, K., Harding, D. R. K., Holmes, A. R., Lamping, E., Niimi, M., Cannon, R. D., & Monk, B. C. (2006). Identifying novel aspects of ABC transporter structure and function using surface-active chemosensitizers. Japanese Journal of Medical Mycology. 47(Suppl. 1), (pp. 67). [Abstract]

Lamping, E., Nakamura, K., Ranchod, A., Holmes, A. R., Niimi, K., Niimi, M., & Cannon, R. D. (2006). Investigating the innate resistance of Candida krusei to azole antifungal drugs. Japanese Journal of Medical Mycology. 47(Suppl. 1), (pp. 67). [Abstract]

Cannon, R. D., Tsao, S., Ong, S.-W., Monk, B. C., Holland, B. R., Schmid, J., & Holmes, A. R. (2006). Allelic variation in Candida albicans drug efflux pumps. Journal of Dental Research, 85(Spec Iss B), 0503. Retrieved from http://www.dentalresearch.org

Yang, N.-C., Ferguson, M. M., & Cannon, R. D. (2006). Is sugar-free confectionery good for your teeth? Journal of Dental Research, 85(Spec Iss B), 1501. Retrieved from http://www.dentalresearch.org

Conference Contribution - Poster Presentation (not in published proceedings)

Niimi, K., Harding, D., Lamping, E., Holmes, A., Niimi, M., Cannon, R., & Monk, B. (2006, June). Identification and characterization of a drug efflux pump inhibitor specific to Candida albicans ABC transporter Cdr1p. Poster session presented at the 16th Congress of the International Society for Human and Animal Mycology, Paris, France.

Niimi, K., Maki, K., Ikeda, F., Holmes, A., Lamping, E., Niimi, M., Monk, B., & Cannon, R. (2006, June). Over-expression of cdr1, cdr2 or mdr1 in Candida albicans does not cause significant changes in candin susceptibility. Poster session presented at the 16th Congress of the International Society for Human and Animal Mycology, Paris, France.

Monk, B., Niimi, K., Lamping, E., Holmes, A., Cannon, R., Harding, D., & Niimi, M. (2006, March). Novel aspects of ABC transporter structure and function identified using a surface-active chemosensitiser. Poster session presented at the Federation of European Biochemical Societies Special Meeting, Innsbruck, Austria.

Yang, N.-C., Ferguson, M. M., & Cannon, R. D. (2006, June-July). Is sugar-free confectionery good for your teeth? Poster session presented at the International Association for Dental Research, Brisbane, Australia.

Lyons, K. M., Cannon, R. D., Holmes, A. R., & Love, R. M. (2006, June-July). Microbial adhesion to prosthetic materials used to restore maxillary defects. Poster session presented at the International Association for Dental Research, Brisbane, Australia.

Conference Contribution - Verbal presentation and other Conference outputs

Lamping, E., Niimi, K., Holmes, A. R., Monk, B., Tanabe, K., Niimi, M., & Cannon, R. D. (2006, November). Studying drug resistance mechanisms of pathogenic fungi. Verbal presentation at the 3rd Molecular Fungal Biology Conference, Chiba, Japan.

Cannon, R. D., Lamping, E., Holmes, A. R., Niimi, K., Niimi, M., & Monk, B. C. (2006, August). Overcoming the efflux-mediated drug resistance of human fungal pathogens. Verbal presentation at the 8th International Mycological Congress, Cairns, Australia.

Cannon, R. D., Rodrigues, E. M., Van der Wielen, P. A., Zhang, N., Schmid, J., Dawes, P. J. D., & Holmes, A. R. (2006, August). Oral adhesion of Candida albicans: A cellular and molecular view. Verbal presentation at the 8th International Mycological Congress, Cairns, Australia.

2005

Journal - Research Article

Lamping, E., Tanabe, K., Niimi, M., Uehara, Y., Monk, B. C., & Cannon, R. D. (2005). Characterization of the Saccharomyces cerevisiae sec6-4¹ mutation and tools to create S. cerevisiae strains containing the sec6-4 allele. Gene, 361, 57-66.

Niimi, M., Tanabe, K., Wada, S.-I., Yamazaki, A., Uehara, Y., Niimi, K., Lamping, E., Holmes, A. R., Monk, B. C., & Cannon, R. D. (2005). ABC transporters of pathogenic fungi: Recent advances in functional analyses. Nippon Ishinkin Gakkai Zasshi, 46(4), 249-260.

Wada, S.-I., Tanabe, K., Yamazaki, A., Niimi, M., Uehara, Y., Niimi, K., Lamping, E., Cannon, R. D., & Monk, B. C. (2005). Phosphorylation of Candida glabrata ATP-binding cassette transporter Cdr1p regulates drug efflux activity and ATPase stability. Journal of Biological Chemistry, 280(1), 94-103.

Jeng, H.-W., Holmes, A. R., & Cannon, R. D. (2005). Characterization of two Candida albicans surface mannoprotein adhesins that bind immobilized saliva components. Medical Mycology, 43, 209-217.

Monk, B. C., Niimi, K., Lin, S., Knight, A., Kardos, T. B., Cannon, R. D., … Harding, D. R. K. (2005). Surface-active fungicidal D-peptide inhibitors of the plasma membrane proton pump that block azole resistance. Antimicrobial Agents & Chemotherapy, 49(1), 57-70. doi: 10.1128/AAC.49.1.57-70.2005

Niimi, M., Wada, S.-I., Tanabe, K., Kaneko, A., Takano, Y., Umeyama, T., … Lamping, E., Niimi, K., Tsao, S., Holmes, A. R., Monk, B. C., & Cannon, R. D. (2005). Functional analysis of fungal drug efflux transporters by heterologous expression in Saccharomyces cerevisiae. Japanese Journal of Infectious Diseases, 58, 1-7.

Conference Contribution - Poster Presentation (not in published proceedings)

Niimi, K., Holmes, A. R., Lamping, E., Maki, K., Ikeda, F., Niimi, M., Monk, B. C., & Cannon, R. D. (2005, November). Are candins substrates of fungal drug efflux pumps? Poster session presented at the Joint Meeting of the New Zealand Microbiological Society and the New Zealand Society for Biochemistry and Molecular Biology, Dunedin, New Zealand.

Lamping, E., Holmes, A. R., Niimi, K., Monk, B. C., Nakamura, K., Niimi, M., & Cannon, R. D. (2005, November). A system for heterologous over-expression of functional membrane proteins in Saccharomyces cerevisiae. Poster session presented at the Proteomics Satellite Meeting, Dunedin, New Zealand.

Niimi, K., Maki, K., Ikeda, F., Holmes, A. R., Lamping, E., Niimi, M., Monk, B. C., & Cannon, R. D. (2005, October). Micafungin is not an efflux pump substrate. Poster session presented at the 49th Annual Meeting of the Japanese Society for Medical Mycology, Chiba, Japan.

Lamping, E., Nakamura, K., Ranchod, A., Holmes, A., Niimi, K., Monk, B., … Niimi, M., & Cannon, R. (2005, May). Genetic tools for the functional hyper-expression of fungal membrane proteins in Saccharomyces cerevisiae. Poster session presented at the Federation of European Biochemical Societies Advanced Lecture Course: Human Fungal Pathogens, La Colle-sur-Loup, France.

Zhang, N., Holland, B. R., Cannon, R. D., & Schmid, J. (2005). Genomic markers associated with increased pathogenicity of Candida albicans. Poster session presented at the International Union of Microbiological Societies 2005: Microbes in a Changing World, San Francisco.

Conference Contribution - Verbal presentation and other Conference outputs

Lamping, E., Nakamura, K., Holmes, A. R., Niimi, K., Monk, B. C., Niimi, M., & Cannon, R. D. (2005, November). A novel, versatile and highly efficient heterologous membrane protein over-expression system. Verbal presentation at the Joint Meeting of the New Zealand Microbiological Society and the New Zealand Society for Biochemistry and Molecular Biology, Dunedin, New Zealand.

Monk, B. C., Niimi, K., Lamping, E., Holmes, A. R., Harding, D. R. K., Niimi, M., & Cannon, R. D. (2005, November). Identifying novel aspects of ABC transporter structure and function using surface-active chemosensitisers. Verbal presentation at the Joint Meeting of the New Zealand Microbiological Society and the New Zealand Society for Biochemistry and Molecular Biology, Dunedin, New Zealand.

Monk, B. C., Niimi, K., Lamping, E., Holmes, A. R., Harding, D. R. K., Niimi, M., & Cannon, R. D. (2005, November). A Saccharomyces cerevisiae system for the heterologous hyper-expression of functional membrane proteins. Verbal presentation at the Proteomics Satellite Meeting, Dunedin, New Zealand.

Holmes, A. R., Tsao, S., Niimi, K., Lamping, E., Niimi, M., . . ., Monk, B. C., & Cannon, R. D. (2005, November). Allelic variation in fungal drug pumps. Verbal presentation at the Joint Meeting of the New Zealand Microbiological Society and the New Zealand Society for Biochemistry and Molecular Biology, Dunedin, New Zealand.

Holmes, A. R., & Cannon, R. D. (2005, October). Amino acid residues critical for drug pump function in Candida albicans. Verbal presentation at the 49th Annual Meeting of the Japanese Society for Medical Mycology, Chiba, Japan.

Holmes, A., van der Wielen, P., Fischer, F., Willix-Payne, D., Hodgkinson, A., & Cannon, R. D. (2005, September). Role of secretory IgA in Candida albicans adhesion. Verbal presentation at the 45th Annual Meeting of the Australian/New Zealand Division of the International Association for Dental Research, Queenstown, New Zealand.

Schmid, J., Zhang, N., Cannon, R. D., Holland, B. R., & Patchett, M. L. (2005, November). Candida albicans ORF 19.6877 is a hypermutable gene. Verbal presentation at the Joint Meeting of the New Zealand Microbiological Society and the New Zealand Society for Biochemistry and Molecular Biology, Dunedin, New Zealand.

Cannon, R. D., Tsao, S., Niimi, K., Ong, S.-W., Lamping, E., Monk, B. C., & Holmes, A. R. (2005, September). Efflux pump-mediated drug resistance in oral fungal pathogens. Verbal presentation at the 45th Annual Meeting of the Australian/New Zealand Division of the International Association for Dental Research, Queenstown, New Zealand.

Cannon, R. D., van der Wielen, P. A., Fischer, F. J., Willix-Payne, D., Hodgkinson, A., & Holmes, A. R. (2005, November). Preventing oral colonisation by Candida albicans. Verbal presentation at the Joint Meeting of the New Zealand Microbiological Society and the New Zealand Society for Biochemistry and Molecular Biology, Dunedin, New Zealand.

2004

Journal - Research Article

Niimi, K., Harding, D. R. K., Parshot, R., King, A., Lun, D. J., Decottignies, A., Niimi, M., … Cannon, R. D., … Monk, B. C. (2004). Chemosensitization of fluconazole resistance in Saccharomyces cerevisiae and pathogenic fungi by a D-octapeptide derivative. Antimicrobial Agents & Chemotherapy, 48(4), 1256-1271.

Schmid, J., Cannon, R. D., & Holland, B. (2004). A futile act? Thoughts on the reproductive biology of Candida albicans. Mycologist, 18, 158-163.

Niimi, M., Niimi, K., Takano, Y., Holmes, A. R., Fischer, F. J., Uehara, Y., & Cannon, R. D. (2004). Regulated overexpression of CDR1 in Candida albicans confers multidrug resistance. Journal of Antimicrobial Chemotherapy, 54(6), 999-1006.

Beggs, K. T., Holmes, A. R., Cannon, R. D., & Rich, A. M. (2004). Detection of Candida albicans mRNA in archival histopathology samples by reverse transcription-PCR. Journal of Clinical Microbiology, 42(5), 2275-2278.

Conference Contribution - Poster Presentation (not in published proceedings)

Zhang, N., Harrex, A. L., Holland, B., Fenton, L., Cannon, R. D., & Schmid, J. (2004, November). Genomic markers associated with increased pathogenicity of Candida albicans. Poster session presented at the New Zealand Microbiological Society Conference: Microbes outside the square, Palmerston North, New Zealand.

Tanabe, K., Wada, S., Yamazaki, A., Niimi, M., Uehara, Y., Niimi, K., Lamping, E., Cannon, R. D., & Monk, B. C. (2004, September). Phosphorylation of Candida glabrata ABC transporter Cdr1p regulates drug efflux and ATPase activities. Poster session presented at the 27th Annual Meeting of the Japanese Society for Molecular Microbiology: Yeast Genetics Forum, Shimane, Japan.

Tanabe, K., Wada, S., Yamazaki, A., Niimi, K., Lamping, E., Cannon, R., Monk, B., … Niimi, M. (2004, December). Phosphorylation of Candida glabrata ATP-binding casselle transporter Cdr1p regulates drug-efflux activity and ATPase stability. Poster session presented at the 27th Annual Meeting of the Molecular Biology Society of Japan, Kobe, Japan.

Lamping, E., Monk, B. C., Niimi, M., & Cannon, R. D. (2004, September). Genetic tools for functional hyper-expression of membrane proteins in Saccharomyces cerevisiae. Poster session presented at the 27th Annual Meeting of the Japanese Society for Molecular Microbiology: Yeast Genetics Forum, Shimane, Japan.

Zhang, N., Harrex, A., Holland, B. R., Fenton, L. E., Cannon, R. D., & Schmid, J. (2004, March). Key features distinguishing more pathogenic, general-purpose genotype, strains from less pathogenic Candida albicans strains: A genomic comparison. Poster session presented at the 7th American Society for Microbiology Conference on Candida and Candidiasis, Austin, Texas.

Cannon, R. D., Tsao, S., Ong, S.-W., Niimi, K., Lamping, E., Niimi, M., Monk, B. C., & Holmes, A. R. (2004, March). Allelic variation effecting drug pump function in Candida albicans. Poster session presented at the 7th American Society for Microbiology Conference on Candida and candidiasis, Austin, Texas.

Dawes, P., Ruske, D., van der Wielen, P., Holmes, A., & Cannon, R. (2004, July). Salivary components promoting adherence of Candida albicans to voice prosthesis silicone rubber. Poster session presented at the The Garnett Passe and Rodney Williams Memorial Foundation Frontiers in Otorhinolaryngology, Noosa, Australia.

Conference Contribution - Verbal presentation and other Conference outputs

Lamping, E., Cannon, R. D., Niimi, K., Tsao, S., Holmes, A. R., Monk, B. C., & ... (2004, August). Drug resistance mechanisms in fungal pathogens-special emphasis on Candida albicans and Cryptococcus neoformans [Invited]. Verbal presentation at the Nippon Dental University, Niigata, Japan.

Ranchod, A., Cannon, R. D., & Lamping, E. (2004, September). Efflux pump-mediated drug resistance in Candida krusei. Verbal presentation at the 44th Annual Meeting of the International Association for Dental Research, Australian and New Zealand Division, Nadi, Fiji.

Cannon, R. D., van der Wielen, P. A., & Holmes, A. R. (2004, September). Mechanisms of oral colonisation by Candida albicans. Verbal presentation at the 44th Annual Meeting of the International Association for Dental Research, Australian and New Zealand Division, Nadi, Fiji.

Cannon, R. D., Tsao, S., Niimi, K., Monk, B. C., & Holmes, A. R. (2004, April). Overcoming the drug resistance of opportunistic oral fungal pathogens. Verbal presentation at the HIV/AIDS Associated Oral Viral Infections, Pathogenesis and Transmission Conference, Bethesda, Maryland.

Holmes, A. R., Tsao, S., Niimi, K., Lamping, E., Niimi, M., Kaneko, A., Monk, B. C., & Cannon, R. D. (2004, November). Amino acid residues critical for drug pump function in Candida albicans. Verbal presentation at the New Zealand Microbiological Society Conference, Palmerston North, New Zealand.

Lamping, E., Nakamura, K., Monk, B. C., Holmes, A. R., Niimi, K., Tsao, S., Niimi, M., & Cannon, R. D. (2004, September). A membrane protein hyper-expression system and its application in the search for new antifungal drugs. Verbal presentation at the 48th Annual Meeting of the Japanese Society for Medical Mycology, Yokohama, Japan.

Cannon, R. D., Tsao, S., Monk, B. C., & Holmes, A. R. (2004, March). Drug efflux mechanisms in Candida albicans. Verbal presentation at the 82nd General Session & Exhibition of the International Association for Dental Research, Honolulu, Hawaii.

Holmes, A. R., van der Wielen, P. A., & Cannon, R. D. (2004, March). Salivary components promoting adherence of Candida albicans to epithelial cells and denture acrylic. Verbal presentation at the 7th Amercian Society for Microbiology Conference on Candida and candidiasis, Austin, Texas.

Dawes, P. J. D., Ruske, D. R., van der Wielen, P., Holmes, A. R., & Cannon, R. D. (2004, September). Salivary components promoting adherence of Candida albicans to voice prosthesis rubber. Verbal presentation at the Royal Australasian College of Surgeons Annual Scientific Meeting, Auckland, New Zealand.

2003

Journal - Research Article

Zhang, N., Harrex, A. L., Holland, B. R., Fenton, L. E., Cannon, R. D., & Schmid, J. (2003). Sixty alleles of the ALS7 open reading frame in Candida albicans: ALS7 Is a hypermutable contingency locus. Genome Research, 13, 2005-2017.

Conference Contribution - Published proceedings: Abstract

Niimi, K., Lamping, E., Holmes, A. R., Monk, B. C., Cannon, R. D., & Niimi, M. (2003). Drug resistance mechanisms in pathogenic fungi. Journal of Japanese Society for Clinical Microbiology, 13(4), (pp. 51). [Abstract]

Ong, S.-W., Tsao, S., Holmes, A. R., Lamping, E., & Cannon, R. D. (2003). Allelic variation of the Candida albicans drug efflux pump Cdr1p. Journal of Dental Research, 82(Spec Iss C), (pp. C108). [Abstract]

Cannon, R. D., Monk, B. C., & Tagg, J. R. (2003). Oral microbiology: New approaches to treatment for oral microbial infections. Journal of Dental Research, 82. [Abstract]

Hull, C. H., Holmes, A. R., Niimi, K., Lamping, E., Monk, B. C., & Cannon, R. D. (2003). Chemosensitisation of multidrug resistant yeast to fluconazole. Journal of Dental Research, 82, (pp. C-78). [Abstract]

Conference Contribution - Poster Presentation (not in published proceedings)

Tsao, S., Holmes, A., Ong, S.-W., Lamping, E., Monk, B., Niimi, K., & Cannon, R. (2003, September). Allelic variations in a Candida albicans drug pump. Poster session presented at the MicroNZ: A Combined Annual Scientific Meeting & Exhibition of the Australian and New Zealand Societies for Microbiology, Auckland, New Zealand.

van der Wielen, P., Holmes, A., & Cannon, R. (2003, September). Interactions of Candida albicans with saliva. Poster session presented at the MicroNZ: A Combined Annual Scientific Meeting & Exhibition of the Australian and New Zealand Societies for Microbiology, Auckland, New Zealand.

Monk, B. C., Niimi, K., Lamping, E., Holmes, A. R., Cannon, R. D., Harding, D. R. K., … Niimi, M., & Uehara, Y. (2003, July). Functional hyper-expression of membrane proteins in yeast and discovery of chemosensitizers of fungal multidrug efflux. Poster session presented at the XXIst International Conference on Yeast Genetics and Molecular Biology, Gothenburg, Sweden.

Cannon, R. D., Harding, D. R. K., Lin, S., Niimi, K., & Monk, B. C. (2003, September). A fungicidal plasma membrane proton pump inhibitor indirectly blocks multidrug efflux. Poster session presented at the MicroNZ: A Combined Annual Scientific Meeting & Exhibition of the Australian and New Zealand Societies for Microbiology, Auckland, New Zealand.

Niimi, M., Wada, S., Niimi, K., Shimokawa, O., Takano, Y., Holmes, A., Monk, B., Cannon, R., & Uehara, Y. (2003, May). Molecular features of the innate fluconazole resistance of Candida glabrata. Poster session presented at the The 15th Congress of the International Society for Human and Animal Mycology, San Antonio, Texas.

Conference Contribution - Verbal presentation and other Conference outputs

Monk, B. C., Niimi, K., Lamping, E., Holmes, A. R., Cannon, R. D., Harding, D. R. K., … Niimi, M., & Uehara, Y. (2003, September). Functional hyper-expression of membrane proteins in yeast and discovery of chemosensitizers of fungal multidrug efflux. Verbal presentation at the EuroConference on Host-Pathogen Interactions: Human fungal pathogens, Giens, France.

Zhang, N., Harrex, A., Holland, B. R., Fenton, L. E., Firth, N. A., Cannon, R. D., & Schmid, J. (2003, September/October). Putative Candida virulence genes from a genomic screen. Verbal presentation at the MicroNZ: A Combined Annual Scientific Meeting & Exhibition of the Australian and New Zealand Societies for Microbiology, Auckland, New Zealand.

Monk, B. C., Niimi, K., Lamping, E., Holmes, A. R., Cannon, R. D., Harding, D. R. K., … Niimi, M., & Uehara, Y. (2003, August). Functional hyper-expression of membrane proteins in yeast and discovery of chemosensitizers of fungal multidrug efflux. Verbal presentation at the 21st Small Meeting on Yeast Transport and Energetics, Bonn, Germany.

Monk, B. C., Niimi, K., Lamping, E., Holmes, A. R., Cannon, R. D., Harding, D. R. K., … Niimi, M., & Uehara, Y. (2003, January). Functional hyper-expression of membrane proteins and discovery of chemosensitizers of fungal multidrug efflux. Verbal presentation at the Symposium on 'ABC Proteins' and the 5th Conference on 'ABC Proteins and Ion Channels': From gene to disease, Kyoto, Japan.

Cannon, R. D. (2003, May). Functional analysis of fungal drug efflux pumps. Verbal presentation at the 15th Congress of the International Society for Human and Animal Mycology, San Antonio, Texas.

2002

Journal - Research Article

Wada, S., Niimi, M., Niimi, K., Holmes, A. R., Monk, B. C., Cannon, R. D., & Uehara, Y. (2002). Candida glabrata ATP-binding cassette transporters Cdr1p and Pdh1p expressed in a Saccharomyces cerevisiae strain deficient in membrane transporters show phosphorylation-dependent pumping properties. Journal of Biological Chemistry, 277, 46809-46821.

Niimi, M., Nagai, Y., Niimi, K., Wada, S.-I., Cannon, R. D., Uehara, Y., & Monk, B. C. (2002). Identification of two proteins induced by exposure of the pathogenic fungus Candida glabrata to fluconazole. Journal of Chromatography B, 782, 245-252.

Monk, B. C., & Cannon, R. D. (2002). Genomic pathways to antifungal discovery. Current Drug Targets: Infectious Disorders, 2, 309-329.

Holmes, A. R., Bandara, M. K., & Cannon, R. D. (2002). Saliva promotes Candida albicans adherence to human epithelial cells. Journal of Dental Research, 81, 28-32.

Holmes, A. R., Niimi, M., Girgis, J. M., Boyd, D. H., & Cannon, R. D. (2002). Antifungal drug susceptibilities of commensal Candida isolates. New Zealand Dental Journal, 98, 36-49.

Conference Contribution - Poster Presentation (not in published proceedings)

Homes, A. R., Niimi, K., Lamping, E., Monk, B. C., & Cannon, R. D. (2002, November). Do SNP's affect multidrug resistance in the fungal pathogen Candida albicans? Poster session presented at the New Zealand Microbiological Society Microbes and Molecules Conference, Christchurch, New Zealand.

Hull, C., Homes, A. R., Niimi, K., Lamping, E., Monk, B. C., & Cannon, R. D. (2002, September). Chemosensitisation of multidrug resistant yeast top Fluconazole. Poster session presented at the 42nd Annual Scientific Meeting of the International Association for Dental Research (ANZ Division), Sydney, Australia.

Niimi, K., Cannon, R. D., Niimi, M., Harding, D. R. K., Goffeau, A., & Monk, B. C. (2002, June). A multidrug efflux pump inhibitor from a D-octapeptide combinatorial library. Poster session presented at the 1st JBS Biofrontier Symposium on Membrane Transporters, Yufuin, Japan.

Niimi, K., Cannon, R. D., Harding, D. R. K., Goffeau, A., & Monk, B. C. (2002, November). D-octapeptide chemosensitizer for saccharomyces cerevisiae hyper expressing ABC multidrug transporters. Poster session presented at the New Zealand Microbiological Society Microbes and Molecules Conference, Christchurch, New Zealand.

Holmes, A. R., Hull, C., Niimi, K., Lamping, R. D., Cannon, R. D., & Monk, B. C. (2002, September). Peptide-mediated inhibition of antifungal resistance-conferring plasma membrane multi-drug efflux pumps. Poster session presented at the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Diego, USA.

Intellectual Property

Monk, B. C., Cannon, R. D., Nakamura, K., Niimi, M., Niimi, K., Harding, D. R. K., Holmes, A. R., Lamping, E., … Decottignies, A. (2002). Membrane protein expression system and its application (International patent). International patent #PCT/NZ02/00163 (filed 24 August 2002). International Patent Office.

Monk, B. C., Nakamura, K., Cannon, R. D., Niimi, M., Niimi, K., Harding, D. R. K., Holmes, A. R., Lamping, E., … Decottignies, A. (2002). Membrane protein expression system and its application (NZ patent). New Zealand provisional patent #513755 (filed 24 August 2001). Intellectual Property Office of New Zealand.

2001

Chapter in Book - Research

Niimi, M., Cannon, R. D., & Monk, B. C. (2001). Candida albicans pathology: A proteomic perspective. In M. J. Dunn (Ed.), Proteomics Reviews 2001. (pp. 28-37). Weinheim, Germany: Wiley-VCH.

Journal - Research Article

Cannon, R. D., & Chaffin, W. L. (2001). Colonization is a crucial factor in oral candidiasis. Journal of Dental Education, 65, 785-787.

Maebashi, K., Niimi, M., Kudoh, M., Fischer, F. J., Makimura, K., Niimi, K., Piper, R. J., … Cannon, R. D., & Yamaguchi, H. (2001). Mechanisms of fluconazole resistance in Candida albicans isolates from Japanese AIDS patients. Journal of Antimicrobial Chemotherapy, 47, 527-536.

Niimi, K., Shepherd, M. G., & Cannon, R. D. (2001). Distinguishing Candida species by β-N-acetylhexosaminidase activity. Journal of Clinical Microbiology, 39, 2089-2097.

Nakamura, K., Niimi, M., Niimi, K., Holmes, A. R., Yates, J. E., Decottignies, A., Monk, B. C., … Cannon, R. D. (2001). Functional expression of Candida albicans drug efflux pump Cdr1p in a Saccharomyces cerevisiae strain deficient in membrane transporters. Antimicrobial Agents & Chemotherapy, 45, 3366-3374.

Conference Contribution - Published proceedings: Abstract

Oh, C., Niimi, M., & Cannon, R. D. (2001). Drug resistance mechanisms in an itraconazole-resistant Candida albicans variant. Abstracts of papers presented at the 40th Annual Meeting of the Australian and New Zealand Division of the International Association for Dental Research. 80. Alexandria VA USA: Journal of Dental Research. [Abstract]

Stewart Saga, J. M., & Cannon, R. D. (2001). Over-expression of GST3 (encoding glutathione S-transterase) confers fluconazoleresistance on Candida albicans. Abstracts of papers presented at the 40th Annual Meeting of the Australian and New Zealand Division of the International Association for Dental Research. 80. Alexandria VA USA: Journal of Dental Research. [Abstract]

Boyd, D. H., Drummond, B. K., Thomson, W. M., & Cannon, R. D. (2001). Candida albicans in the dental plaque of New Zealand children. Abstracts of papers presented at the Internetional Association for Dental Research 79th General Assembly. 80. Alexandria VA USA: Journal of Dental Research. [Abstract]

2000

Journal - Research Article

O'Sullivan, J. M., Jenkinson, H. F., & Cannon, R. D. (2000). Adhesion of Candida albicans to oral streptococci is promoted by selective adsorbtion of salivary proteins to the streptococcal cell surface. Microbiology, 146, 41-48.

Calderone, R., Suzuki, S., Cannon, R., Cho, T., Boyd, D., Calera, J., … Holmes, A., Jeng, H.-W., … O'Sullivan, J. M., … Tompkins, G. R., & Watanabe, T. (2000). Candida albicans: Adherence, signalling and virulence. Medical Mycology, 38(Suppl. 1), 125-137.

Niimi, K., Niimi, M., Shepherd, M. G., & Cannon, R. D. (2000). N-Acetylhexosaminidase of the pathogenic yeast Candida albicans. Recent Research Development in Microbiology, 4, 85-100.

Conference Contribution - Published proceedings: Abstract

Jeng, H.-W., Holmes, A. R., Tompkins, G. R., & Cannon, R. D. (2000). Candida albicans adhesins recognising salivary basic proline rich proteins. IADR (78th General Assembly). 79(Abstracts supplement). Journal of Dental Research. [Abstract]

Nakamura, K., Niimi, M., Niimi, K., Cannon, R. D., Goffeau, A., Balzi, E., … Monk, B. C. (2000). Functional expression of Candida albicans multiple drug efflux pump Cdr1 in Saccharomyces cerevisiae. Abstracts of papers presented at the 44th Annual Meeting of Japanese Society for Medical Mycology. 41. Tokyo, Japan: Japanese Society for Medical Mycology. [Abstract]

1999

Journal - Research Article

Cannon, R. D., & Chaffin, W. L. (1999). Oral colonization by Candida albicans. Critical Reviews in Oral Biology & Medicine, (10), 359-383.

Niimi, M., Niimi, K., & Cannon, R. D. (1999). Drug resistance mechanisms in opportunistic fungal pathogens. Dental Outlook, 93, 1368-1376.

Schmid, J., Herd, S., Hunter, P. R., Cannon, R. D., Yasin, M. S. M., Samad, S., … Schousboe, M., … Singh, K. P. (1999). Evidence for a general-purpose genotype in Candida albicans, highly prevalent in multiple geographical regions, patient types and types of infection. Microbiology, 145, 2405-2413.

Niimi, M., Cannon, R. D., & Monk, B. C. (1999). Candida albicans pathogenicity: A proteomic perspective. Electrophoresis, 20, 2299-2308.

Perepnikhatka, V., Fischer, F. J., Niimi, M., Baker, R. A., Cannon, R. D., Wang, Y.-K., … Rustchenko, E. (1999). Specific chromosome alterations in fluconazole-resistant mutants of Candida albicans. Journal of Bacteriology, 181, 4041-4049.

Conference Contribution - Published proceedings: Abstract

Shin, C. Y., Fischer, F. J., Niimi, M., & Cannon, R. D. (1999). Isolation and characterisation of antifungal resistant Candida albicans variants. Abstracts of papers presented at the 38th Annual Meeting of the Australian and New Zealand division of the International Association for Dental Research. 78. Alexandria VA USA: Journal of Dental Research. [Abstract]

1998

Journal - Research Article

Niimi, K., Shepherd, M. G., & Cannon, R. D. (1998). Candida albicans HEX1 gene, a reporter of gene expression in Saccharomyces cerevisiae. Archives of Microbiology, 170, 113-119.

Cannon, R. D., Fischer, F. J., Niimi, K., Niimi, M., & Arisawa, M. (1998). Drug pumping mechanisms in Candida albicans. Nippon Ishinkin Gakkai Zasshi, 39, 73-78.

Conference Contribution - Published proceedings: Abstract

Jeng, H.-W., Holmes, A. R., Tompkins, G. R., & Cannon, R. D. (1998). Identification of Candida albicans adhesins that recognise salivary proteins. New Zealand Microbiological Society Annual Meeting. [Abstract]

Cannon, R. D., O'Sullivan, J. M., & Holmes, A. R. (1998). Adherence of Candida albicans in the oral cavity. IADR (Australian and New Zealand Division) 37th Annual Meeting. 77(Abstracts Supplement). Journal of Dental Research. [Abstract]

Yeung, J., Niimi, M., & Cannon, R. D. (1998). Isolation of yeast secretory vesicles containing a purative drug pump. Abstracts of papers presented at the 37th Annual Meeting of the Australia and New Zealand Division of the International Association for Dental Research. 77. Alexandria VA USA: Journal of Dental Research. [Abstract]

O'Sullivan, J. M., Jenkinson, H. F., & Cannon, R. D. (1998). Salivary proteins absorbed onto streptococci promote binding of Candida albicans. Abstracts of papers presented at the 37th Annual Meeting of the Australia and New Zealand Division of the International Association for Dental Research. 77. Alexandria VA USA: Journal of Dental Research. [Abstract]

Niimi, M., Fischer, F. J., Arisawa, M., & Cannon, R. D. (1998). Expression of the CDR1 gene and multidrug resistance in Candida albicans. Abstracts of papers presented at the 37th Annual Meeting of the Australia and New Zealand Division of the International Association for Dental Research. 77. Alexandria VA USA: Journal of Dental Research. [Abstract]

1997

Journal - Research Article

Niimi, K., Niimi, M., Shepherd, M. G., & Cannon, R. D. (1997). Regulation of N-acetylglucosaminidase production in Candida albicans. Archives of Microbiology, 168, 464-472.

O'Sullivan, J. M., Cannon, R. D., Sullivan, P. A., & Jenkinson, H. F. (1997). Identification of salivary basic proline-rich proteins as receptors for Candida albicans adhesion. Microbiology, 143, 341-348.

Niimi, M., Cannon, R. D., & Arisawa, M. (1997). Multidrug resistance genes in Candida albicans. Nippon Ishinkin Gakkai Zasshi, 38, 297-302.

Niimi, M., Niimi, K., & Cannon, R. D. (1997). Temperature-related expression of the vacuolar aspartic proteinase (APR1) gene and Beta-N-acetylglucosaminidase (HEX1) gene during Candida albicans morphogenesis. FEMS Microbiology Letters, 148, 247-254.

Mirbod, F., Nakashima, S., Kitajima, Y., Cannon, R. D., & Nozawa, Y. (1997). Molecular cloning of a Rho family, CDC42Ca gene from Candida albicans and its mRNA expression changes during morphogenesis. Journal of Medical & Veterinary Mycology, 35, 173-179.

1996

Chapter in Book - Research

Cannon, R. D., Albertson, G. D., Niimi, M., & Jenkinson, H. F. A. (1996). Fluconazole uptake and resistance in Candida. In K. Tanaka, H. Yamaguchi & P. T. Magee (Eds.), Genes and Genomes in Medically Important Fungi. (pp. 157-165). Foundation for Advancement of International Scienc.

Journal - Research Article

Mirbod, F., Nakashima, S., Kitajima, Y., Ghannoum, M. A., Cannon, R. D., & Nozawa, Y. (1996). Molecular cloning of a gene encoding translation initiation factor(TIF) from Candida albicans. Journal of Medical & Veterinary Mycology, 34(6), 393-400.

Albertson, G. D., Niimi, M., Cannon, R. D., & Jenkinson, H. F. (1996). Multiple efflux mechanisms are involved in Candida albicans fluconazole resistance. Antimicrobial Agents & Chemotherapy, 40(12), 2835-2841.

1995

Journal - Research Article

Holmes, A. R., Cannon, R. D., & Jenkinson, H. F. A. (1995). Interactions of Candida albicans with bacteria and salivary molecules in oral biofilms. Journal of Industrial Microbiology, 15, 208-213.

Schmid, J., Hunter, P. R., White, K., Nand, A. K., & Cannon, R. D. (1995). Physiological traits associated with success of Candida albicans strains as commensal colonizers and pathogens. Journal of Clinical Microbiology, 33, 2920-2926.