Contact Details
- Phone
- 64 3 470 9362
- jan.cowan@otago.ac.nz
- Position
- Research Manager
- Department
- Department of Medicine (Dunedin)
- Research summary
- Respiratory research including breath analysis, biomarkers, sputum biomarkers, and clinical trials
Research
- 30 years’ experience in undertaking investigator led and commercial clinical trials. Very experienced in trial set-up, ethics and regulatory submissions, and all aspects of undertaking a clinical trial.
- 40 years’ experience in laboratory skills,including HSNO requirements.
Research interests include asthma, COPD, CF, IPF, bronchiectasis, OSA, breath analysis, inflammatory biomarkers, FeNO, sputum, and airway challenges.
Publications
Singh, A., Cowan, J., & Dummer, J. (2020). The effect of mode of inhaled salbutamol delivery on measures of small airways obstruction in asthma: A comparison of treatment delivered via spacer and nebuliser. New Zealand Medical Student Journal, (30), 21-25. Journal - Research Article
Hannaway, R. F., Wang, X., Schneider, M., Slow, S., Cowan, J., Brockway, B., Schofield, M. R., Morgan, X. C., Murdoch, D. R., & Ussher, J. E. (2020). Mucosal-associated invariant T cells and Vδ2+ γδ T cells in community acquired pneumonia: Association of abundance in sputum with clinical severity and outcome. Clinical & Experimental Immunology, 199(2), 201-215. doi: 10.1111/cei.13377 Journal - Research Article
Dummer, J., Cowan, J., Tewhaiti-Smith, J., Aluzaite, K., Fitzgerald, C., & Schultz, M. (2018). Lung health in New Zealand gang members: Results from a health hui. Respirology, 23(Suppl. 1), (pp. 208). doi: 10.1111/resp.13268 Conference Contribution - Published proceedings: Abstract
Dummer, J., Amer, M., Cowan, J., & Gray, A. (2017). The relationship between fractional exhaled nitric oxide and forced expiratory volume in one second in asthma. American Journal of Respiratory & Critical Care Medicine, 195, A1314. [Abstract] Conference Contribution - Published proceedings: Abstract
McEvoy, R. D., Antic, N. A., Heeley, E., Luo, Y., Ou, Q., Zhang, X., … for the SAVE Investigators and Coordinators, including Epton, M. J., Brockway, B., Cowan, J., Taylor, D. R., Palmay, R., Ferrier, K., & Neill, A. (2016). CPAP for prevention of cardiovascular events in obstructive sleep apnea. New England Journal of Medicine, 375(10), 919-932. doi: 10.1056/NEJMoa1606599 Journal - Research Article
2020
Journal - Research Article
Singh, A., Cowan, J., & Dummer, J. (2020). The effect of mode of inhaled salbutamol delivery on measures of small airways obstruction in asthma: A comparison of treatment delivered via spacer and nebuliser. New Zealand Medical Student Journal, (30), 21-25.
Hannaway, R. F., Wang, X., Schneider, M., Slow, S., Cowan, J., Brockway, B., Schofield, M. R., Morgan, X. C., Murdoch, D. R., & Ussher, J. E. (2020). Mucosal-associated invariant T cells and Vδ2+ γδ T cells in community acquired pneumonia: Association of abundance in sputum with clinical severity and outcome. Clinical & Experimental Immunology, 199(2), 201-215. doi: 10.1111/cei.13377
2018
Conference Contribution - Published proceedings: Abstract
Dummer, J., Cowan, J., Tewhaiti-Smith, J., Aluzaite, K., Fitzgerald, C., & Schultz, M. (2018). Lung health in New Zealand gang members: Results from a health hui. Respirology, 23(Suppl. 1), (pp. 208). doi: 10.1111/resp.13268
2017
Conference Contribution - Published proceedings: Abstract
Dummer, J., Amer, M., Cowan, J., & Gray, A. (2017). The relationship between fractional exhaled nitric oxide and forced expiratory volume in one second in asthma. American Journal of Respiratory & Critical Care Medicine, 195, A1314. [Abstract]
2016
Journal - Research Article
McEvoy, R. D., Antic, N. A., Heeley, E., Luo, Y., Ou, Q., Zhang, X., … for the SAVE Investigators and Coordinators, including Epton, M. J., Brockway, B., Cowan, J., Taylor, D. R., Palmay, R., Ferrier, K., & Neill, A. (2016). CPAP for prevention of cardiovascular events in obstructive sleep apnea. New England Journal of Medicine, 375(10), 919-932. doi: 10.1056/NEJMoa1606599
Amer, M., Cowan, J., Gray, A., Brockway, B., & Dummer, J. (2016). Effect of inhaled β2-agonist on exhaled nitric oxide in chronic obstructive pulmonary disease. PLoS ONE, 11(6), e0157019. doi: 10.1371/journal.pone.0157019
Wang, G., Baines, K. J., Fu, J. J., Wood, L. G., Simpson, J. L., McDonald, V. M., Cowan, D. C., Taylor, D. R., Cowan, J. O., & Gibson, P. G. (2016). Sputum mast cell subtypes relate to eosinophilia and corticosteroid response in asthma. European Respiratory Journal, 47, 1123-1133. doi: 10.1183/13993003.01098-2015
2015
Journal - Research Article
Cowan, D. C., Taylor, D. R., Peterson, L. E., Cowan, J. O., Palmay, R., Williamson, A., … Comhair, S. A. A. (2015). Biomarker-based asthma phenotypes of corticosteroid response. Journal of Allergy & Clinical Immunology, 135(4), 877-883.e1. doi: 10.1016/j.jaci.2014.10.026
Conference Contribution - Published proceedings: Abstract
Brockway, B., Senthilmohan, R., Jones, S., Cowan, J., Herbison, P., Hancox, B., Taylor, R., Van Dalen, C. J., & Kettle, T. (2015). Elevated sputum 3-bromotyrsoine levels are associated with loss of control in asthma. American Journal of Respiratory & Critical Care Medicine, 191(Meeting Abstracts). Retrieved from http://www.atsjournals.org/series/ajrccm-conference
2014
Journal - Research Article
Baines, K. J., Simpson, J. L., Wood, L. G., Scott, R. J., Fibbens, N. L., Powell, H., Cowan, D. C., Taylor, D. R., Cowan, J. O., & Gibson, P. G. (2014). Sputum gene expression signature of 6 biomarkers discriminates asthma inflammatory phenotypes. Journal of Allergy & Clinical Immunology, 133(4), 997-1007. doi: 10.1016/j.jaci.2013.12.1091
2013
Journal - Research Article
van der Schee, M. P., Palmay, R., Cowan, J. O., & Taylor, D. R. (2013). Predicting steroid responsiveness in patients with asthma using exhaled breath profiling. Clinical & Experimental Allergy, 43(11), 1217-1225. doi: 10.1111/cea.12147
2012
Journal - Research Article
Hancox, R. J., Cowan, D. C., Aldridge, R. E., Cowan, J. O., Palmay, R., Williamson, A., Town, G. I., & Taylor, D. R. (2012). Asthma phenotypes: Consistency of classification using induced sputum. Respirology, 17(3), 461-466. doi: 10.1111/j.1440-1843.2011.02113.x
2011
Journal - Research Article
Leon de la Barra, S., Smith, A. D., Cowan, J. O., Herbison, G. P., & Taylor, D. R. (2011). Predicted versus absolute values in the application of exhaled nitric oxide measurements. Respiratory Medicine, 105(11), 1629-1634. doi: 10.1016/j.rmed.2011.06.001
Taylor, D. R., Palmay, R., Cowan, J. O., & Herbison, G. P. (2011). Long term performance characteristics of an electrochemical nitric oxide analyser. Respiratory Medicine, 105(2), 211-217. doi: 10.1016/j.rmed.2010.09.001
2010
Journal - Research Article
Cowan, D. C., Cowan, J. O., Palmay, R., Williamson, A., & Taylor, D. R. (2010). Simvastatin in the treatment of asthma: Lack of steroid-sparing effect. Thorax, 65(10), 891-896. doi: 10.1136/thx.2010.138990
Cowan, D. C., Cowan, J. O., Palmay, R., Williamson, A., & Taylor, D. R. (2010). Effects of steroid therapy on inflammatory cell subtypes in asthma. Thorax, 65(5), 384-390. doi: 10.1136/thx.2009.126722
Cowan, D. C., Hewitt, R. S., Cowan, J. O., Palmay, R., Williamson, A., Lucas, S. J. E., Murrell, C. J., Thomas, K. N., & Taylor, D. R. (2010). Exercise-induced wheeze: Fraction of exhaled nitric oxide-directed management. Respirology, 15, 683-690. doi: 10.1111/j.1440-1843.2010.01740.x
Cowan, D. C., Cowan, J. O., Palmay, R., Williamson, A., & Taylor, D. R. (2010). The effects of steroid therapy on inflammatory cell subtypes in asthma. Thorax, 65, 384-390. doi: 10.1136/thx.2009.126722
2009
Journal - Research Article
Hewitt, R. S., Modrich, C. M., Cowan, J. O., Herbison, G. P., & Taylor, D. R. (2009). Outcomes using exhaled nitric oxide measurements as an adjunct to primary care asthma management. Primary Care Respiratory Journal, 18(4), 320-327. doi: 10.4104/pcrj.2009.00060
Smith, A. D., Cowan, J. O., & Taylor, D. R. (2009). Exhaled nitric oxide levels in asthma: Personal best versus reference values. Journal of Allergy & Clinical Immunology, 124(4), 714-718. doi: 10.1016/j.jaci.2009.07.020
van Dalen, C. J., Aldridge, R. E., Chan, T., Senthilmohan, R., Hancox, R. J., Cowan, J. O., Taylor, D. R., Town, G. I., & Kettle, A. J. (2009). Bromotyrosines in sputum proteins and treatment effects of terbutaline and budesonide in asthma. Annals of Allergy, Asthma & Immunology, 103(4), 348-353.
Dummer, J. F., Epton, M. J., Cowan, J. O., Cook, J. M., Condliffe, R., Landhuis, C. E., Smith, A. D., & Taylor, D. R. (2009). Predicting corticosteroid response in chronic obstructive pulmonary disease using exhaled nitric oxide. American Journal of Respiratory & Critical Care Medicine, 180(9), 846-852. doi: 10.1164/rccm.200905-0685OC
Conference Contribution - Published proceedings: Abstract
Skinner, M. A., Sutherland, T. J. T., Cowan, J. O., & Taylor, D. R. (2009). Static and dynamic changes in thoracic function following bariatric surgery for patients with morbid obesity. e-Australian Journal of Physiotherapy. 55(4, Suppl.), (pp. 23). [Abstract]
2008
Journal - Research Article
Hewitt, R. S., Modrich, C. M., Medlicott, T., Cowan, J. O., & Taylor, D. R. (2008). Supporting the diagnosis of non-specific respiratory symptoms in primary care: The role of exhaled nitric oxide measurement and spirometry. Primary Care Respiratory Journal, 17(2), 97-103. doi: 10.1136/pgmj.2007.064493
Sutherland, T. J. T., Goulding, A., Grant, A. M., Cowan, J. O., Williamson, A., Williams, S. M., Skinner, M. A., & Taylor, D. R. (2008). The effect of adiposity measured by dual-energy X-ray absorptiometry on lung function. European Respiratory Journal, 32, 85-91. doi: 10.1183/09031936.00112407
Sutherland, T. J. T., Cowan, J. O., & Taylor, D. R. (2008). Dynamic hyperinflation with bronchoconstriction: Differences between obese and nonobese women with asthma. American Journal of Respiratory & Critical Care Medicine, 177, 970-975.
Hewitt, R. S., Smith, A. D., Cowan, J. O., Schofield, J. C., Herbison, G. P., & Taylor, D. R. (2008). Serial exhaled nitric oxide measurements in the assessment of laboratory animal allergy. Journal of Asthma, 45, 101-107. doi: 10.1080/02770900701767696
Sutherland, T. J. T., Cowan, J. O., Young, S., Goulding, A., Grant, A. M., Williamson, A., Brassett, K., Herbison, G. P., & Taylor, D. R. (2008). The association between obesity and asthma: Interactions between systemic and airway inflammation. American Journal of Respiratory & Critical Care Medicine, 178, 469-475. doi: 10.1164/rccm.200802-301OC
2007
Journal - Research Article
McLachlan, C. R., Poulton, R., Car, G., Cowan, J., Filsell, S., Greene, J. M., Taylor, D. R., Welch, D., Williamson, A., … Hancox, R. J. (2007). Adiposity, asthma, and airway inflammation. Journal of Allergy & Clinical Immunology, 119(3), 634-639.
Taylor, D. R., Mandhane, P., Greene, J. M., Hancox, R. J., Filsell, S., McLachlan, C. R., Williamson, A. J., Cowan, J. O., Smith, A. D., & Sears, M. R. (2007). Factors affecting exhaled nitric oxide measurements: The effect of sex. Respiratory Research, 8. Retrieved from http://respiratory-research.com/content/8/1/82
Sutherland, T. J. T., Taylor, D. R., Sears, M. R., Cowan, J. O., McLachlan, C. R., Filsell, S., Williamson, A., … Poulton, R., & Hancox, R. J. (2007). Association between exhaled nitric oxide and systemic inflammatory markers. Annals of Allergy, Asthma & Immunology, 99(4), 334-339.
Conference Contribution - Published proceedings: Abstract
Sutherland, T. J. T., Taylor, D. R., Sears, M. R., Cowan, J. O., McLachlan, C. R., Filsell, S., Williamson, A., … Poulton, R., & Hancox, R. J. (2007). Airway and systematic inflammation: Is exhaled nitric oxide associated with C-reactive protein or fibrinogen? Proceedings of the American Thoracic Society International Conference. Retrieved from http://www.abstracts2view.com/ats07/view.php?nu=ATS07L_1226
2006
Journal - Research Article
Hancox, R. J., Poulton, R., Taylor, D. R., Greene, J. M., McLachlan, C. R., Cowan, J. O., Flannery, E. M., Herbison, G. P., … Talley, N. J. (2006). Associations between respiratory symptoms, lung function and gastro-oesophageal reflux symptoms in a population-based birth cohort. Respiratory Research, 7. doi: 10.1186/1465-9921-7-142
Conference Contribution - Published proceedings: Abstract
McLachlan, C. R., Cowan, J. O., Filsell, S. J., Greene, J. M., Poulton, R., Sears, M. R., Taylor, D. R., … Hancox, R. J. (2006). Adiposity, asthma and airway inflammation. European Respiratory Journal, 28(Suppl. 50), (pp. 235s). [Abstract]
2005
Journal - Research Article
Smith, A. D., Cowan, J. O., Brassett, K. P., Filsell, S., McLachlan, C., Monti-Sheehan, G., Herbison, G. P., & Taylor, D. R. (2005). Exhaled nitric oxide: A predictor of steroid response. American Journal of Respiratory & Critical Care Medicine, 172, 453-459.
Smith, A. D., Cowan, J. O., Brassett, K. P., Herbison, G. P., & Taylor, D. R. (2005). Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. New England Journal of Medicine, 352(21), 2163-2173.
Hancox, R. J., Milne, B. J., Poulton, R., Taylor, D. R., Greene, J. M., McLachlan, C. R., Cowan, J. O., Flannery, E. M., Herbison, G. P., & Sears, M. R. (2005). Sex differences in the relation between body mass index and asthma and atopy in a birth cohort. American Journal of Respiratory & Critical Care Medicine, 171(5), 440-445.
Mandhane, P. J., Greene, J. M., Cowan, J. O., Taylor, D. R., & Sears, M. R. (2005). Sex differences in factors associated with childhood- and adolescent-onset wheeze. American Journal of Respiratory & Critical Care Medicine, 172(1), 45-54.
Taylor, D. R., Cowan, J. O., Greene, J. M., Willan, A. R., & Sears, M. R. (2005). Asthma in remission: Can relapse in early adulthood be predicted at 18 years of age? Chest, 127(3), 845-850.
Skinner, M. A., Choudhury, M. S., Homan, S. D., Cowan, J. O., Wilkins, G. T., & Taylor, D. R. (2005). Accuracy of monitoring for sleep-related breathing disorders in the coronary care unit. Chest, 127(1), 66-71.
Taylor, D. R., Epton, M. J., Kennedy, M. A., Smith, A. D., Iles, S., Miller, A. L., Littlejohn, M. D., Cowan, J. O., Hewitt, T., Swanney, M. P., Brassett, K. P., & Herbison, G. P. (2005). Bronchodilator response in relation to β2-adrenoceptor haplotype in patients with asthma. American Journal of Respiratory & Critical Care Medicine, 172(6), 700-703.
Conference Contribution - Published proceedings: Abstract
Hancox, R. J., Poulton, R., Taylor, D. R., Greene, J. M., McLachlan, C. R., Cowan, J. O., Flannery, E. M., Herbison, G. P., … Talley, N. J. (2005). Gastro-oesophageal reflux symptoms are associated with asthma in a population-based cohort study. Respirology, 10(Suppl.), (pp. A36). doi: 10.1111/j.1440-1843.2005.00663.x-i1
Hancox, R. J., Poulton, R., Taylor, D. R., Greene, J. M., McLachlan, C. R., Cowan, J. O., Flannery, E. M., Herbison, G. P., … Talley, N. J. (2005). Associations between gastro-oesophageal reflux and asthma in a birth cohort. European Respiratory Journal, 26(Suppl.49), (pp. 661S). [Abstract]
Hancox, R. J., Milne, B., Poulton, R., Taylor, D. R., Greene, J. M., McLachlan, C. R., Cowan, J. O., Flannery, E. M., Herbison, G. P., & Sears, M. R. (2005). Sex differences in the relation between body mass index and asthma and atopy in a birth cohort study. Respirology, 10(Suppl.), (pp. A34). doi: 10.1111/j.1440-1843.2005.00663.x-i1
Skinner, M. A., Choudhury, M. S., Homan, S. D., Cowan, J. O., Wilkins, G. T., & Taylor, D. R. (2005). Frequency of sleep-related breathing disorders in patients presenting with acute cardiovascular events. Proceedings of the Australian Physiotherapy Association 9th National Cardiothoracic Group Conference. (pp. 73). Melbourne, Australia: APA. [Abstract]
2004
Journal - Research Article
Wraight, J. M., Smith, A. D., Cowan, J. O., Flannery, E. M., Herbison, G. P., & Taylor, D. R. (2004). Adverse effects of short-acting beta-agonists: Potential impact when anti-inflammatory therapy is inadequate. Respirology, 9, 215-221.
Kingshott, R. N., Cowan, J. O., Jones, D. R., Flannery, E. M., Smith, A. D., Herbison, G. P., & Taylor, D. R. (2004). The role of sleep-disordered breathing, daytime sleepiness, and impaired performance in motor vehicle crashes: A case control study. Sleep & Breathing, 8(2), 61-72.
Taylor, E. S., Smith, A. D., Cowan, J. O., Herbison, G. P., & Taylor, D. R. (2004). Effect of caffeine ingestion on exhaled nitric oxide measurements in patients with asthma. American Journal of Respiratory & Critical Care Medicine, 169(9), 1019-1021.
Smith, A. D., Cowan, J. O., Filsell, S., McLachlan, C., Monti-Sheehan, G., Jackson, P., & Taylor, D. R. (2004). Diagnosing asthma: Comparisons between exhaled nitric oxide measurements and conventional tests. American Journal of Respiratory & Critical Care Medicine, 169, 473-478.
Hancox, R. J., Milne, B. J., Taylor, D. R., Greene, J. M., Cowan, J. O., Flannery, E. M., Herbison, G. P., McLachlan, C. R., Poulton, R., & Sears, M. R. (2004). Relationship between socioeconomic status and asthma: A longitudinal cohort study. Thorax, 59, 376-380.
Conference Contribution - Published proceedings: Abstract
Skinner, M., Choudhury, M., Homan, S., Cowan, J., Wilkins, G., & Taylor, R. (2004). Accuracy of monitoring for sleep-related breathing disorders in the coronary care unit. Proceedings of the 17th Annual Scientific Meeting of the Australasian Sleep Association. [Abstract]
2003
Journal - Research Article
Sears, M. R., Greene, J., Willan, A. R., Wiecek, E. M., Taylor, D. R., Flannery, E., Cowan, J. O., Herbison, G. P., Silva, P. A., & Poulton, R. (2003). A longitudinal, population-based, cohort study of childhood asthma followed to adulthood. New England Journal of Medicine, 349(15), 1414-1422.
Wraight, J. M., Hancox, R. J., Herbison, G. P., Cowan, J. O., Flannery, E., & Taylor, D. R. (2003). Bronchodilator tolerance: The impact of increasing bronchoconstriction. European Respiratory Journal, 21, 810-815.
Conference Contribution - Published proceedings: Abstract
Smith, A. D., Cowan, J. O., Filsell, S., McLachlan, C., Monti-Sheehan, G., Jackson, P., & Taylor, D. R. (2003). Confirming the diagnosis of asthma: Comparisons between exhaled nitric oxide measurements, induced sputum analysis and conventional lung function tests. New Zealand Medical Journal, 116(1186). Retrieved from http://journal.nzma.org.nz/journal/116-1186/689/content.pdf
Taylor, D. R., Greene, J. M., Cowan, J. O., Herbison, G. P., & Sears, M. R. (2003). Recurrence of childhood asthma between ages 18 and 26 years. American Journal of Respiratory and Critical Care Medicine. 167, (pp. A855). [Abstract]
2002
Journal - Research Article
Jones, S. L., Herbison, G. P., Cowan, J. O., Flannery, E., Hancox, R. J., McLachlan, C., & Taylor, D. R. (2002). Exhaled NO and assessment of anti-inflammatory effects of inhaled steroid: Dose-response relationship. European Respiratory Journal, 20, 601-608. doi: 10.1183/09031936.02.00285302
Aldridge, R. E., Hancox, R. J., Cowan, J. O., Frampton, C. M., Town, G. I., & Taylor, D. R. (2002). Eosinophils and eosinophil cationic protein in induced sputum and blood: Effects of budesonide and terbutaline treatment. Annals of Allergy, Asthma & Immunology, 89(5), 492-497.
Rasmussen, F., Taylor, D. R., Flannery, E., Cowan, J. O., Greene, J., Herbison, G. P., & Sears, M. R. (2002). Outcome in adulthood of asymptomatic airway hyperresponsiveness in childhood: A longitudinal population study. Pediatric Pulmonology, 34(3), 164-171.
McRae, W. M., Flannery, E., Cowan, J. O., McLachlan, C. R., Herbison, G. P., Siebers, R. W. L., Crane, J., & Wong, C. S. (2002). House dust mite allergen levels in University student accommodation in Dunedin. New Zealand Medical Journal, 115(1157), U30. Retrieved from http://www.nzma.org.nz/journal/115-1157/30
Sears, M. R., Greene, J. M., Willan, A. R., Taylor, D. R., Flannery, E., Cowan, J. O., Herbison, G. P., & Poulton, R. (2002). Long-term relation between breastfeeding and development of atopy and asthma in children and young adults: A longitudinal study. Lancet, 360, 901-907.
Rasmussen, F., Taylor, D. R., Flannery, E., Cowan, J. O., Greene, J., Herbison, G. P., & Sears, M. R. (2002). Risk factors for hospital admission for asthma from childhood to young adulthood; a longitudinal population study. Journal of Allergy & Clinical Immunology, 110(2), 219-227.
Rasmussen, F., Taylor, D. R., Flannery, E., Cowan, J. O., Greene, J., Herbison, G. P., & Sears, M. R. (2002). Risk factors for airway remodeling in asthma manifested by a low postbronchodilator FEV1/vital capacity ratio: a longitudinal population study from childhood to adulthood. American Journal of Respiratory & Critical Care Medicine, 165, 1480-1488.
Wraight, J. M., Cowan, J. O., Flannery, E., Town, G. I., & Taylor, D. R. (2002). Adherence to asthma self-management plans with inhaled corticosteroid and oral prednisone: A descriptive analysis. Respirology, 7(2), 133-139.
2001
Journal - Research Article
Jones, S. L., Kittelson, J. M., Cowan, J. O., Flannery, E., Hancox, R. J., McLachlan, C., & Taylor, D. R. (2001). The predictive value of exhaled nitric oxide measurements in assessing changes in asthma control. American Journal of Respiratory & Critical Care Medicine, 164(5), 738-743.
Jones, S. L., Cowan, J. O., Flannery, E., Hancox, R. J., Herbison, G. P., & Taylor, D. R. (2001). Reversing acute bronchoconstriction in asthma: The effect of bronchodilator tolerance after treatment with formoterol. European Respiratory Journal, 17, 368-373.
Conference Contribution - Published proceedings: Abstract
Wraight, J. M., Herbison, G. P., Cowan, J. O., Flannery, E., Hancox, R. J., & Taylor, D. R. (2001). Tolerance to the acute bronchodilator effects of beta-agonist with increasing degrees of bronchoconstriction. Respirology, 6(Suppl.). [Abstract]
2000
Journal - Research Article
Taylor, D. R., Hancox, R. J., McRae, W. M., Cowan, J. O., Flannery, E., McLachlan, C. R., & Herbison, G. P. (2000). The influence of polymorphism at position 16 of the β2-adrenoceptor on the development of tolerance to β-agonist. Journal of Asthma, 37(8), 691-700.
Hancox, R. J., Cowan, J. O., Flannery, E., Herbison, G. P., McLachlan, C. R., & Taylor, D. R. R. (2000). Bronchodilator tolerance and rebound bronchoconstriction during regular inhaled β-agonist treatment. Respiratory Medicine, 94, 767-771.
Aldridge, R., Hancox, R. J., Taylor, D. R., Cowan, J. O., Winn, M. C., Frampton, C. M., & Town, G. I. (2000). Effects of terbutaline and budesonide on sputum cells and bronchial hyperresponsiveness in asthma. American Journal of Respiratory & Critical Care Medicine, 161, 1459-1464.
Conference Contribution - Published proceedings: Abstract
Jones, S. L., Cowan, J. O., Flannery, E., Herbison, G. P., Hancox, R. J., & Taylor, D. R. (2000). Bronchodilator tolerance during acute bronchoconstriction in patients taking inhaled formoterol. European Respiratory Journal. 16, (pp. 753). [Abstract]
Aldridge, R., Town, G. I., Hancox, R. J., Cowan, J. O., Winn, M. C., Chan, T., Frampton, C. M., & Taylor, D. R. (2000). Eosinophils and eosinophil cationic protein in induced sputum compared to blood: Effects of budesonide and terbutaline treatment. European Respiratory Journal. 16, (pp. 785). [Abstract]
Jones, S. L., Kittelson, J. M., Cowan, J. O., McLachlan, C., Flannery, E., Hancox, R. J., & Taylor, D. R. (2000). Exhaled nitric oxide in stable asthma - week to week variation and correlation with other inflammatory markers. European Respiratory Journal. 16, (pp. 3703). [Abstract]
Jones, S. L., Kittelson, J. M., Cowan, J. O., McLachlan, C., Flannery, E., Hancox, R. J., & Taylor, D. R. (2000). Exhaled nitric oxide as a predictor of deteriorating asthma. European Respiratory Journal. 16, (pp. 3690). [Abstract]
1999
Journal - Research Article
Hancox, R. J., Aldridge, R., Cowan, J. O., Flannery, E., Herbison, G. P., McLachlan, C., Town, G. I., & Taylor, D. R. (1999). Tolerance to beta-agonists during acute bronchoconstriction. European Respiratory Journal, 14(2), 283-287.
Ramsay, C. M., Cowan, J. O., Flannery, E., McLachlan, C., & Taylor, D. R. (1999). Bronchoprotective and bronchodilator effects of single doses of (S)-salbutamol, (R)-salbutamol and racemic salbutamol in patients with bronchial asthma. European Journal of Clinical Pharmacology, 55(5), 353-359.
Hancox, R. J., Cowan, J. O., Flannery, E., Herbison, G. P., McLachlan, C., Wong, C. S., & Taylor, D. R. R. (1999). A randomized trial of inhaled beta-agonist, inhaled corticosteroid and their combination in the treatment of asthma. Thorax, 54, 482-487.
Conference Contribution - Published proceedings: Abstract
Taylor, D. R., Hancox, R. J., McRae, W. M., Cowan, J. O., Flannery, E., McLachlan, C. R., & Herbison, G. P. (1999). Polymorphism of the β2-adrenoceptor and the development of tolerance during treatment with inhaled salmeterol. American Journal of Respiratory and Critical Care Medicine. 159. [Abstract]
Aldridge, R., Hancox, R. J., Cowan, J. O., Winn, M. C., Frampton, C. M., Town, G. I., & Taylor, D. R. (1999). Effects of beta-agonists and corticosteroids on airway physiology and inflammatory indices. American Journal of Respiratory and Critical Care Medicine. 159(3 A878). [Abstract]
1997
Conference Contribution - Published proceedings: Abstract
Hancox, R. J., Cowan, J. O., Flannery, E., Herbison, G. P., McLachlan, C. R., Wong, C. S., & Taylor, D. R. (1997). Interactions between inhaled beta-agonists and inhaled corticosteroids in the control of asthma. Thorax. 52 (suppl). [Abstract]