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Contact Details

Phone
64 3 372 0647
Email
peter.sykes@otago.ac.nz
Position
Associate Professor
Department
Department of Obstetrics and Gynaecology (Christchurch)
Qualifications
MBChB (Brist) DipObst (Otago) FRNZCOG DGO
Research summary
Gynaecological Oncology

Research

Peter joined the Department in 1998 and was appointed Head of Department in 2009 until 2015. He completed his undergraduate training in the United Kingdom and specialised in Obstetrics and Gynaecology in New Zealand. He subsequently completed his sub-specialty training in gynaecological oncology in Melbourne and his interests include gynaecological oncology and advanced preinvasive disease of the genital tract.

Publications

Ingamells, S., Bell, R., Nip, J., Innes, C., Te Whaiti, S., Tino, A., McBain, L., McMenamin, J., Hudson, B., … Lawton, B., & Sykes, P. (2024). Perceived barriers to self-collected HPV testing for cervical cancer screening, and knowledge of HPV: A survey of primary healthcare smear-takers across Aotearoa New Zealand. New Zealand Medical Journal/Te ara tika o te hauora hapori, 137(1590), 57-76. Retrieved from https://www.nzmj.org.nz/

Nagao, S., Fujiwara, K., Yamamoto, K., Tanabe, H., Okamoto, A., Takehara, K., … Sykes, P., … Enomoto, T. (2023). Intraperitoneal carboplatin for ovarian cancer - A phase 2/3 trial. NEJM Evidence, 2(5). doi: 10.1056/EVIDoa2200225

Majid, M. A., Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2023). The effects of the obesity-related hormones leptin, insulin, IGF-I and adiponectin on Ishikawa and HEC-1A, MCF-7 and SKOV-3 cancer cell lines. EC Gynaecology, 12(8). Retrieved from https://ecronicon.net/ec_gynaecology

Chitcholtan, K., Dyer, A., & Sykes, P. (2023). Predicting tumour progression of ID-8 syngeneic mouse ovarian cancer with blood biomarkers fo CA-125, IL-6 and VEGF: A prospective laboratory-based study. Clinical & Experimental Obstetrics & Gynaecology, 50(10), 212. doi: 10.31083/j.ceog5010212

Lawton, B., MacDonald, E. J., Storey, F., Stanton, J.-A., Adcock, A., Gibson, M., … King, F., … Watson, H., Bennett, M., Lambert, C. S., Geller, S., Paasi, I., Hibma, M., Sykes, P., Hawkes, D., & Saville, M. (2023). A model for empowering rural solutions for cervical cancer prevention (He Tapu Te Whare Tangata): Protocol for a cluster randomized crossover trial. JMIR Research Protocols, 12, e51643. doi: 10.2196/51643

Sykes, P. (2013). Obstetrics and Gynaecology. In P. Joyce, G. Nicholls, K. Thomas & T. Wilkinson (Eds.), The Christchurch experience: 40 years of research and teaching. (pp. 33-37). Christchurch, New Zealand: University of Otago.

Chapter in Book - Other

Ingamells, S., Bell, R., Nip, J., Innes, C., Te Whaiti, S., Tino, A., McBain, L., McMenamin, J., Hudson, B., … Lawton, B., & Sykes, P. (2024). Perceived barriers to self-collected HPV testing for cervical cancer screening, and knowledge of HPV: A survey of primary healthcare smear-takers across Aotearoa New Zealand. New Zealand Medical Journal/Te ara tika o te hauora hapori, 137(1590), 57-76. Retrieved from https://www.nzmj.org.nz/

Journal - Research Article

Borchowsky, K., Rush, M., Mullally, T., McBain, L., Hudson, B., McMenamin, J., … Sykes, P., & Garrett, S. (2023). Primary care experiences in the 'Let's test for HPV' study: A qualitative analysis. Journal of Primary Health Care, 15(2), 147-154. doi: 10.1071/HC23038

Journal - Research Article

Cabasag, C. J., Arnold, M., Rutherford, M., Ferlay, J., Bardot, A., Morgan, E., … Sykes, P., … Soerjomataram, I. (2023). Shifting incidence and survival of epithelial ovarian cancer (1995-2014): A SurvMark-2 study. International Journal of Cancer, 152, 1763-1777. doi: 10.1002/ijc.34403

Journal - Research Article

Chitcholtan, K., Dyer, A., & Sykes, P. (2023). Predicting tumour progression of ID-8 syngeneic mouse ovarian cancer with blood biomarkers fo CA-125, IL-6 and VEGF: A prospective laboratory-based study. Clinical & Experimental Obstetrics & Gynaecology, 50(10), 212. doi: 10.31083/j.ceog5010212

Journal - Research Article

Kumar, D., Moghiseh, M., Chitcholtan, K., Mutreja, I., Lowe, C., Kaushik, A., Butler, A., Sykes, P., Anderson, N., & Raja, A. (2023). LHRH conjugated gold nanoparticles assisted efficient ovarian cancer targeting evaluated via spectral photon-counting CT imaging: A proof-of-concept research. Journal of Materials Chemistry B. Advance online publication. doi: 10.1039/d2tb02416k

Journal - Research Article

Majid, M. A., Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2023). The effects of the obesity-related hormones leptin, insulin, IGF-I and adiponectin on Ishikawa and HEC-1A, MCF-7 and SKOV-3 cancer cell lines. EC Gynaecology, 12(8). Retrieved from https://ecronicon.net/ec_gynaecology

Journal - Research Article

Mertens, R. C. E., Sykes, P. H., Innes, C. R., Simcock, B. J., & Petrich, S. (2023). Endometrial cancer diagnoses prompted by routine cervical cytology: A retrospective case study. New Zealand Medical Journal/Te ara tika o te hauora hapori, 136(1581), 56-65. Retrieved from https://journal.nzma.org.nz/

Journal - Research Article

Nagao, S., Fujiwara, K., Yamamoto, K., Tanabe, H., Okamoto, A., Takehara, K., … Sykes, P., … Enomoto, T. (2023). Intraperitoneal carboplatin for ovarian cancer - A phase 2/3 trial. NEJM Evidence, 2(5). doi: 10.1056/EVIDoa2200225

Journal - Research Article

Saito, M., Rajesh, A., Innes, C., van der Griend, R., Fitzgerald, P., Simcock, B., Sykes, P., & Hibma, M. (2023). The high-risk human papillomavirus type influences the tissue microenvironment in cervical intraepithelial neoplasia grade 2. Viruses, 15, 1953. doi: 10.3390/v15091953

Journal - Research Article

Dunn, E., Chitcholtan, K., Sykes, P., & Garrill, A. (2022). The anti-proliferative effect of PI3K/mTOR and ERK inhibition in monolayer and three-dimensional ovarian cancer cell models. Cancers, 14, 395. doi: 10.3390/cancers14020395

Journal - Research Article

Saito, M., Rajesh, A., Innes, C., van der Griend, R., Fitzgerald, P., Simcock, B., Sykes, P., & Hibma, M. (2022). Blimp-1 is a prognostic indicator for progression of cervical intraepithelial neoplasia grade 2. Journal of Cancer Research & Clinical Oncology, 148, 1991-2002. doi: 10.1007/s00432-022-03993-4

Journal - Research Article

Sarwar, M., Sykes, P. H., Chitcholtan, K., & Evans, J. J. (2022). Collagen I dysregulation is pivotal for ovarian cancer progression. Tissue & Cell, 74, 101704. doi: 10.1016/j.tice.2021.101704

Journal - Research Article

Sykes, P. H., Simcock, B. J., Innes, C. R., Harker, D., Williman, J. A., Whitehead, M., van der Griend, R. A., … Hibma, M., … Petrich, S., … Sadler, L. (2022). Predicting regression of cervical intraepithelial neoplasia grade 2 in women under 25 years. American Journal of Obstetrics & Gynecology, 226, 222.e1-222.e13. doi: 10.1016/j.ajog.2021.09.009

Journal - Research Article

Edmonson, R. J., O'Connell, R. L., Banerjee, S., Mileshkin, L., Sykes, P., Beale, P., … on behalf of PARAGON Investigators. (2021). Phase 2 study of anastrozole in rare cohorts of patients with estrogen receptor/progesterone receptor positive leiomyosarcomas and carcinosarcomas of the uterine corpus: The PARAGON trial (ANZGOG 0903). Gynecologic Oncology, 163, 524-530. doi: 10.1016/j.ygyno.2021.09.010

Journal - Research Article

Janda, M., Robledo, K. P., Gebski, V., Armes, J. E., Alizart, M., Cummings, M., … Sykes, P., … Obermair, A. (2021). Complete pathological response following levonorgestrel intrauterine device in clinically stage 1 endometrial adenocarcinoma: Results of a randomized clinical trial. Gynecologic Oncology, 161(1), 143-151. doi: 10.1016/j.ygyno.2021.01.029

Journal - Research Article

Sarwar, M., Sykes, P. H., Chitcholtan, K., & Evans, J. J. (2021). Deciphering biophysical modulation in ovarian cancer cells. Cell Biochemistry & Biophysics, 79, 375-386. doi: 10.1007/s12013-020-00964-9

Journal - Research Article

Cabasag, C. J., Butler, J., Arnold, M., Rutherford, M., Bardot, A., Ferlay, J., … Sykes, P., … Soerjomataram, I. (2020). Exploring variations in ovarian cancer survival by age and stage (ICBP SurvMark-2): A population-based study. Gynecologic Oncology, 157, 234-244. doi: 10.1016/j.ygyno.2019.12.047

Journal - Research Article

Chitcholtan, K., Harker, D., Simcock, B., & Sykes, P. (2020). Sensitivity of EGFR/HER-2 positive cells isolated from ascitic fluid of advanced ovarian cancer patients to EGFR/HER-2 inhibitors. Applied Sciences, 10(7), 2343. doi: 10.3390/app10072343

Journal - Research Article

Cohen, P. A., Leung, Y., Anderson, L., van der Griend, R., Chivers, P., Bilic, S., … Harker, D., … Simcock, B., … Sykes, P., … Wrede, C. D. H. (2020). Excisional treatment comparison for in situ endocervical adenocarcinoma (EXCISE): A phase 2 pilot randomized controlled trial to compare histopathological margin status, specimen size and fragmentation after loop electrosurgical excision procedure and cold knife cone biopsy. Gynecologic Oncology, 159, 623-629. doi: 10.1016/j.ygyno.2020.09.053

Journal - Research Article

Dempster-Rivett, K., Innes, C. R., Simcock, B. J., Harker, D., Williman, J. A., Van Der Griend, R. A., Whitehead, M., Hibma, M., … Petrich, S., Faherty, J., … Sykes, P. H. (2020). Evaluation of guidelines for observational management of cervical intraepithelial neoplasia 2 in young women. American Journal of Obstetrics & Gynecology, 223, 408.e1-408.e11. doi: 10.1016/j.ajog.2020.02.029

Journal - Research Article

Goyani, A. D., Innes, C. R., Simcock, B. J., Harker, D., Dudley, N. M., Eva, L., Bergzoll, C., MacNab, H., & Sykes, P. H. (2020). Trends in the diagnosis of high-grade cervical abnormalities in young women in the post-vaccination era. New Zealand Medical Journal, 133(1524), 50-63. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Innes, C. R. H., Williman, J. A., Simcock, B. J., Hider, P., Sage, M., Dempster-Rivett, K., … Sykes, P. H. (2020). Impact of human papillomavirus vaccination on rates of abnormal cervical cytology and histology in young New Zealand women. New Zealand Medical Journal, 133(1508), 72-84. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Norell, C. H., Butler, J., Farrell, R., Altman, A., Bentley, J., Cabasag, C. J., … Sykes, P. H., … Harrison, S. (2020). Exploring international differences in ovarian cancer treatment: A comparison of clinical practice guidelines and patterns of care. International Journal of Gynecological Cancer, 30, 1748-1756. doi: 10.1136/ijgc-2020-001403

Journal - Research Article

Adcock, A., Cram, F., Lawton, B., Geller, S., Hibma, M., Sykes, P., … Hart, S. (2019). Acceptability of self-taken vaginal HPV sample for cervical screening among an under-screened Indigenous population. Australian & New Zealand Journal of Obstetrics & Gynaecology, 59, 301-307. doi: 10.1111/ajo.12933

Journal - Research Article

Cohen, P. A., Powell, A., Böhm, S., Gilks, C. B., Stewart, C. J. R., Meniawy, T. M., … van der Griend, R., … the HGSC CRS Collaborative Network, including Simcock, B., Sykes, P., Vaughan, M. M., & Singh, N. (2019). Pathological chemotherapy response score is prognostic in tubo-ovarian high-grade serous carcinoma: A systematic review and meta-analysis of individual patient data. Gynecologic Oncology, 154, 441-448. doi: 10.1016/j.ygyno.2019.04.679

Journal - Research Article

Ekeroma, A. J., Naik, S., & Sykes, P. (2019). Systematic review of effective cervical cancer treatments in Small Island Developing States: A narrative synthesis. Pacific Journal of Reproductive Health, (8), 462-474. doi: 10.18313/pjrh.2019.906

Journal - Research Article

Fraser, K., Tan, A. L., Innes, C., Stephens, R., Tristram, A., Petrich, S., Lintott, C., Sykes, P. H., … Simcock, B. (2019). Patterns of referral and uptake of BReast CAncer (BRCA) gene testing of eligible women with ovarian cancer in New Zealand. New Zealand Medical Journal, 132(1490), 26-35. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Sarwar, M., Sykes, P. H., Chitcholtan, K., Alkaisi, M. M., & Evans, J. J. (2019). The extracellular topographical environment influences ovarian cancer cell behaviour. Biochemical & Biophysical Research Communications, 508, 1188-1194. doi: 10.1016/j.bbrc.2018.12.067

Journal - Research Article

Sykes, P., Eva, L., van der Griend, R., McNally, O., Blomfield, P., Brand, A., … Petrich, S., Kenwright, D., … Innes, C., Harker, D., … Simcock, B. (2019). Pathological process has a crucial role in sentinel node biopsy for vulvar cancer. Gynecologic Oncology, 153, 292-296. doi: 10.1016/j.ygyno.2019.02.012

Journal - Research Article

Tang, M., O'Connell, R. L., Amant, F., Beale, P., McNally, O., Sjoquist, K. M., … Sykes, P., … Friedlander, M. (2019). PARAGON: A phase II study of anastrozole in patients with estrogen receptor-positive recurrent/metastatic low-grade ovarian cancers and serous borderline ovarian tumors. Gynecologic Oncology, 154, 531-538. doi: 10.1016/j.ygyno.2019.06.011

Journal - Research Article

Yeoh, S., Simcock, B., Innes, C., Mclachlan, J., Harker, D., & Sykes, P. (2019). Trends in the overall survival rates in women with advanced ovarian cancer in a single tertiary centre in New Zealand. Australian & New Zealand Journal of Obstetrics & Gynaecology, 59, 861-866. doi: 10.1111/ajo.13076

Journal - Research Article

Evans, G. E., Phillipson, G. T. M., Sykes, P. H., McNoe, L. A., Print, C. G., & Evans, J. J. (2018). Does the endometrial gene expression of fertile women vary within and between cycles? Human Reproduction, 33(3), 452-463. doi: 10.1093/humrep/dex385

Journal - Research Article

Hassan, W., Chitcholtan, K., Sykes, P., & Garrill, A. (2018). Ascitic fluid from advanced ovarian cancer patients compromises the activity of receptor tyrosine kinase inhibitors in 3D cell clusters of ovarian cancer cells. Cancer Letters, 420, 168-181. doi: 10.1016/j.canlet.2018.02.013

Journal - Research Article

Hider, P., Dempster-Rivett, K., Williman, J., Dempster-Rivett, M., Sadler, L., McLeod, M., Miller, A., & Sykes, P. (2018). A review of cervical cancer occurrences in New Zealand 2008–2012. New Zealand Medical Journal, 131(1472), 53-63. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Innes, C. R., Sykes, P. H., Harker, D., Williman, J. A., Van der Griend, R. A., Whitehead, M., Hibma, M., … Petrich, S., Faherty, J., … Simcock, B. J. (2018). Changes in human papillomavirus genotypes associated with cervical intraepithelial neoplasia grade 2 lesions in a cohort of young women (2013–2016). Papillomavirus Research, 6, 77-82. doi: 10.1016/j.pvr.2018.10.010

Journal - Research Article

Jamieson, A., Sykes, P., Eva, L., Bergzoll, C., & Simcock, B. (2017). Subtypes of stage IV ovarian cancer: Response to treatment and patterns of disease recurrence. Gynecologic Oncology, 146(2), 273-278. doi: 10.1016/j.ygyno.2017.05.023

Journal - Research Article

Janda, M., Gebski, V., Davies, L. C., Forder, P., Brand, A., Hogg, R., … Sykes, P., … Simcock, B., … Obermair, A. (2017). Effect of total laparoscopic hysterectomy vs total abdominal hysterectomy on disease-free survival among women with stage 1 endometrial cancer: A randomised clinical trial. JAMA, 317(12), 1224-1233. doi: 10.1001/jama.2017.2068

Journal - Research Article

Kumar, D., Mutreja, I., Chitcholtan, K., & Sykes, P. (2017). Cytotoxicity and cellular uptake of different sized gold nanoparticles in ovarian cancer cells. Nanotechnology, 28, 475101. doi: 10.1088/1361-6528/aa935e

Journal - Research Article

Lindemann, K., Kok, P.-S., Stockler, M., Sykes, P., & Brand, A. (2017). Enhanced recovery after surgery for suspected ovarian malignancy: A survey of perioperative practice among gynecologic oncologists in Australia and New Zealand to inform a clinical trial. International Journal of Gynecological Cancer, 27(5), 1046-1050. doi: 10.1097/igc.0000000000000982

Journal - Research Article

Taghavi, K., Morell, S., Lamb, J., MacNab, H., Innes, C., Coffey, K., Williman, J., Simcock, B., & Sykes, P. (2017). Initial observation of CIN2 does not appear to reduce quality of life in women under 25 years of age. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(4), 473-478. doi: 10.1111/ajo.12633

Journal - Research Article

Tan, L. H., Sykes, P. H., Alkaisi, M. M., & Evans, J. J. (2017). Cell-like features imprinted in the physical nano- and micro-topography of the environment modify the responses to anti-cancer drugs of endometrial cancer cells. Biofabrication, 9(1), 015017. doi: 10.1088/1758-5090/aa5c9a

Journal - Research Article

Hassan, W., Chitcholtan, K., Sykes, P., & Garrill, A. (2016). A combination of two receptor tyrosine kinase inhibitors, canertinib and PHA665752 comprises ovarian cancer cell growth in 3D cell models. Oncology & Therapy, 4(2), 257-274. doi: 10.1007/s40487-016-0031-1

Journal - Research Article

Kumar, D., Mutreja, I., & Sykes, P. (2016). Seed mediated synthesis of highly mono-dispersed gold nanoparticles in the presence of hydroquinone. Nanotechnology, 27, 355601. doi: 10.1088/0957-4484/27/35/355601

Journal - Research Article

Stravens, M., Short, J., Johnson, K., Simcock, B., Shand, B., McGeoch, G., & Sykes, P. (2016). Management of postmenopausal bleeding by general practitioners in a community setting: An observational study. New Zealand Medical Journal, 129(1434), 59-68. Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Tino, A. B., Chitcholtan, K., Sykes, P. H., & Garrill, A. (2016). Resveratrol and acetyl-resveratrol modulate activity of VEGF and IL-8 in ovarian cancer cell aggregates via attenuation of the NF-κB protein. Journal of Ovarian Research, 9, 84. doi: 10.1186/s13048-016-0293-0

Journal - Research Article

Hogg, S. J., Chitcholtan, K., Hassan, W., Sykes, P. H., & Garrill, A. (2015). Resveratrol, acetyl-resveratrol, and polydatin exhibit antigrowth activity against 3D cell aggregates of the SKOV-3 and OVCAR-8 ovarian cancer cell lines. Obstetrics & Gynecology International, 2015, 279591. doi: 10.1155/2015/279591

Journal - Research Article

Hogg, S. J., Evans, J. J., Sykes, P. H., & Chitcholtan, K. (2015). A method to investigate the anti-metabolic activity of anti-cancer agents on ovarian cancer cells cultured in a 96-well high throughput format. Journal of Ovarian Research, 8, 43. doi: 10.1186/s13048-015-0172-0

Journal - Research Article

Slatter, T. L., Hsia, H., Samaranayaka, A., Sykes, P., Clow, W., Devenish, C. J., … Royds, J. A., … Hung, N. A. (2015). Loss of ATRX and DAXX expression identifies poor prognosis for smooth muscle tumours of uncertain malignant potential and early stage uterine leiomyosarcoma. Journal of Pathology: Clinical Research, 1(2), 95-105. doi: 10.1002/cjp2.11

Journal - Research Article

Tan, L. H., Sykes, P. H., Alkaisi, M. M., & Evans, J. J. (2015). The characteristics of Ishikawa endometrial cancer cells are modified by substrate topography with cell-like features and the polymer surface. International Journal of Nanomedicine, 10, 4883-4895. doi: 10.2147/ijn.s86336

Journal - Research Article

Wilkinson, T. M., Sykes, P. H. H., Simcock, B., & Petrich, S. (2015). Recurrence of high-grade cervical abnormalities following conservative management of cervical intraepithelial neoplasia grade 2. American Journal of Obstetrics & Gynecology, 212(6), 769.e1-769.e7. doi: 10.1016/j.ajog.2015.01.010

Journal - Research Article

Amant, F., Floquet, A., Friedlander, M., Kristensen, G., Mahner, S., Nam, E. J., … Sykes, P., … Seddon, B. (2014). Gynecological Cancer InterGroup (GCIG) consensus review for endometrial stromal sarcoma. International Journal of Gynecological Cancer, 24(9, Suppl. 3), S67-S72. doi: 10.1097/igc.0000000000000205

Journal - Research Article

Evans, G. E., Martínez-Conejero, J. A., Phillipson, G. T. M., Sykes, P. H., Sin, I. L., Lam, E. Y. N., … Evans, J. J. (2014). In the secretory endometria of women, luminal epithelia exhibit gene and protein expressions that differ from those of glandular epithelia. Fertility & Sterility, 102(1), 307-317. doi: 10.1016/j.fertnstert.2014.04.005

Journal - Research Article

Lawton, B., Filoche, S. K., Rose, S. B., Stanley, J., Garrett, S., Robson, B., Brown, S., & Sykes, P. (2014). Uterine cancer: Exploring access to services in the public health system. Australian & New Zealand Journal of Obstetrics & Gynaecology, 54(5), 457-461. doi: 10.1111/ajo.12237

Journal - Research Article

Sykes, P., Gopala, K., Tan, A. L., Kenwright, D., Petrich, S., Molijn, A., & Chen, J. (2014). Type distribution of human papillomavirus among adult women diagnosed with invasive cervical cancer (stage 1b or higher) in New Zealand. BMC Infectious Diseases, 14, 374. doi: 10.1186/1471-2334-14-374

Journal - Research Article

Chitcholtan, K., Asselin, E., Parent, S., Sykes, P. H., & Evans, J. J. (2013). Differences in growth properties of endometrial cancer in three dimensional (3D) culture and 2D cell monolayer. Experimental Cell Research, 319(1), 75-87. doi: 10.1016/j.yexcr.2012.09.012

Journal - Research Article

Kang, M. Y., Sykes, P., Herbison, P., & Petrich, S. (2013). Retrospective analysis on timeframes of referral, diagnosis and treatment of patients with endometrial carcinomas in Dunedin Hospital, 2008–2011. New Zealand Medical Journal, 126(1384). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2012). The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer. Journal of Translational Medicine, 10(1), 38-53. doi: 10.1186/1479-5876-10-38

Journal - Research Article

Evans, G. E., Martínez-Conejero, J. A., Phillipson, G. T. M., Simón, C., McNoe, L. A., Sykes, P. H., … Evans, J. J. (2012). Gene and protein expression signature of endometrial glandular and stromal compartments during the window of implantation. Fertility & Sterility, 97(6), 1365-1373. doi: 10.1016/j.fertnstert.2012.03.007

Journal - Research Article

Evans, J. J., Chitcholtan, K., Dann, J. M., Guilford, P., Harris, G., Lewis, L. K., Nagase, J., … Sykes, P. H. (2012). Adrenomedullin interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades. Gynecologic Oncology, 125(1), 214-219. doi: 10.1016/j.ygyno.2011.12.429

Journal - Research Article

Kondalsamy-Chennakesavan, S., Janda, M., Gebski, V., Baker, J., Brand, A., Hogg, R., … Sykes, P., … Simcock, B., … Obermair, A. (2012). Risk factors to predict the incidence of surgical adverse events following open or laparoscopic surgery for apparent early stage endometrial cancer: Results from a randomised controlled trial. European Journal of Cancer, 48(14), 2155-2162. doi: 10.1016/j.ejca.2012.03.013

Journal - Research Article

Kondalsamy-Chennakesavan, S., Yu, C., Kattan, M. W., Leung, Y., Sykes, P., Nascimento, M., … Obermair, A. (2012). Nomograms to predict isolated loco-regional or distant recurrence among women with uterine cancer. Gynecologic Oncology, 125(3), 520-525. doi: 10.1016/j.ygyno.2012.02.022

Journal - Research Article

Lawton, B. A., Rose, S. B., Pullon, S., Stanley, J., Garrett, S., Sykes, P., Cormack, D., Robson, B., Langdana, F., Cooper, A., & Filoche, S. K. (2012). The impact of outpatient booking systems on waiting times for investigation of suspected cancer: The case of post-menopausal bleeding. Clinical Ovarian & Other Gynecologic Cancer, 5(2), 87-93. doi: 10.1016/j.cogc.2013.06.001

Journal - Research Article

Obermair, A., Janda, M., Baker, J., Kondalsamy-Chennakesavan, S., Brand, A., Hogg, R., … Sykes, P., … Simcock, B., … Gebski, V. (2012). Improved surgical safety after laparoscopic compared to open surgery for apparent early stage endometrial cancer: Results from a randomised controlled trial. European Journal of Cancer, 48(8), 1147-1153. doi: 10.1016/j.ejca.2012.02.055

Journal - Research Article

Sykes, P., Vaughan, M., Chrystal, K., Ehrenberg, N., Hefford, M., Hutchings, S., … Ngan Kee, D. (2012). Providing care for women with gynaecological malignancy: The need for a coordinated national approach. New Zealand Medical Journal, 125(1360). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

McAllum, B., Sykes, P. H. H., Sadler, L., MacNab, H., Simcock, B. J., & Mekhail, A. K. (2011). Is the treatment of CIN 2 always necessary in women under 25? American Journal of Obstetrics & Gynecology, 205(5), 478.e1-478.e7. doi: 10.1016/j.ajog.2011.06.069

Journal - Research Article

McLeod, M., Cormack, D., Harris, R., Robson, B., Sykes, P., & Crengle, S. (2011). Achieving equitable outcomes for Māori women with cervical cancer in New Zealand: Health provider views. New Zealand Medical Journal, 124(1334). Retrieved from http://journal.nzma.org.nz/journal/124-1334/4661/content.pdf

Journal - Research Article

Obermair, A., Mileshkin, L., Bolz, K., Kondalsamy-Chennakesavan, S., Cheuk, R., Vasey, P., … Sykes, P., & Janda, M. (2011). Prospective, non-randomized phase 2 clinical trial of carboplatin plus paclitaxel with sequential radical pelvic radiotherapy for uterine papillary serous carcinoma. Gynecologic Oncology, 120(2), 179-184. doi: 10.1016/j.ygyno.2010.10.039

Journal - Research Article

Janda, M., Gebski, V., Brand, A., Hogg, R., Jobling, T. W., Land, R., … Sykes, P., … Obermair, A. (2010). Quality of life after total laparoscopic hysterectomy versus total abdominal hysterectomy for stage I endometrial cancer (LACE): A randomised trial. Lancet Oncology, 11(8), 772-780. doi: 10.1016/S1470-2045(10)70145-5

Journal - Research Article

Kuiper, C., Molenaar, I. G. M., Dachs, G. U., Currie, M. J., Sykes, P. H., & Vissers, M. C. M. (2010). Low ascorbate levels are associated with increased hypoxia-inducible factor-1 activity and an aggressive tumor phenotype in endometrial cancer. Cancer Research, 70(14), 5749-5758. doi: 10.1158/0008-5472.CAN-10-0263

Journal - Research Article

McLeod, M., Harris, R., Purdie, G., Cormack, D., Robson, B., Sykes, P., Crengle, S., Iupati, D., & Walker, N. (2010). Improving survival disparities in cervical cancer between Māori and non-Māori women in New Zealand: A National Retrospective Cohort Study. Australian & New Zealand Journal of Public Health, 34(2), 193-199. doi: 10.1111/j.1753-6405.2010.00506.x

Journal - Research Article

Priest, P., Sadler, L., Sykes, P., Marshall, R., Peters, J., & Crengle, S. (2010). Determinants of inequalities in cervical cancer stage at diagnosis and survival in New Zealand. Cancer Causes & Control, 21, 209-214. doi: 10.1007/s10552-009-9451-7

Journal - Research Article

Smart, O. C., Sykes, P., McNab, H., & Jennings, L. (2010). Testing for high risk human papilloma virus in the initial follow-up of women treated for high-grade squamous intraepithelial lesions. Australian & New Zealand Journal of Obstetrics & Gynaecology, 50(2), 164-167. doi: 10.1111/j.1479-828X.2009.01132.x

Journal - Research Article

Dann, J. M., Sykes, P. H., Mason, D. R., & Evans, J. J. (2009). Regulation of Vascular Endothelial Growth Factor in endometrial tumour cells by resveratrol and EGCG. Gynecologic Oncology, 113(3), 374-378.

Journal - Research Article

Su, H. Y., & Sykes, P. H. (2009). Waiting times for gynaecological cancer surgery. New Zealand Medical Journal, 122(1305). Retrieved from http://journal.nzma.org.nz/journal/122-1305/3854/content.pdf

Journal - Research Article

Sykes, P. H., Harker, D. Y., Miller, A., Whitehead, M., Neal, H., Wells, J. E., & Peddie, D. (2008). A randomised comparison of SurePath liquid-based cytology and conventional smear cytology in a colposcopy clinic setting. BJOG, 115(11), 1375-1381. doi: 10.1111/j.1471-0528.2008.01865.x

Journal - Research Article

Jones, R. W., Coughlan, E. P., Reid, J. S., Sykes, P., Watson, P. D., & Cook, C. (2007). Human papilloma virus vaccines and their role in cancer prevention. New Zealand Medical Journal, 120(1266). Retrieved from http://journal.nzma.org.nz/journal/120-1266/2829/content.pdf

Journal - Research Article

Muys, J. J., Alkaisi, M. M., Melville, D. O. S., Nagase, J., Sykes, P., Parguez, G. M., & Evans, J. J. (2006). Cellular transfer and AFM imaging of cancer cells using Bioimprint. Journal of Nanobiotechnology, 4. Retrieved from http://www.jnanobiotechnology.com/content/4/1/1

Journal - Research Article

Watson, A. J., Smith, B. B., Whitehead, M. R., Sykes, P. H., & Frizelle, F. A. (2006). Malignant progression of anal intra-epithelial neoplasia. ANZ Journal of Surgery, 76(8), 715-717.

Journal - Research Article

Pather, S., Ford, M., Reid, R., & Sykes, P. (2005). Postpartum curettage: An audit of 200 cases. Australian & New Zealand Journal of Obstetrics & Gynaecology, 45, 368-371.

Journal - Research Article

Sadler, L., & Sykes, P. (2005). How little is known about cervical cancer in pregnancy? [Editorial]. Annals of Oncology, 16, 341-343.

Journal - Research Article

Sykes, P. H., Reddy, J., & Peddie, D. J. (2005). Does regular cervical screening protect women from microinvasive squamous cell carcinoma of the cervix? A retrospective case-control study. BJOG, 112, 807-809.

Journal - Research Article

Sykes, P., Harker, D., & Peddie, D. (2005). Findings and outcome of teenage women referred for colposcopy at Christchurch Women's Hospital, New Zealand. New Zealand Medical Journal, 118(1211). Retrieved from http://journal.nzma.org.nz/journal/118-1211/1350/content.pdf

Journal - Research Article

Sykes, P., Jennings, L., Harker, D., & Beynon, K. (2005). Human papilloma virus is detectable by the Hybrid Capture 2 test in cervical smear samples from women over 40 years of age with high-grade squamous intraepithelial lesions. Australian & New Zealand Journal of Obstetrics & Gynaecology, 45, 457-459.

Journal - Research Article

Abbas, M. M., Evans, J. J., Sykes, P. H., & Benny, P. S. (2004). Modulation of vascular endothelial growth factor and thymidine phosphorylase in normal human endometrial stromal cells. Fertility & Sterility, 82(Suppl. 3), 1048-1053.

Journal - Research Article

Jones, S., Sykes, P., Pather, S., & Peddie, D. (2004). Is there a role for colposcopy in the follow-up of treated low grade squamous intraepithelial lesions? Australian & New Zealand Journal of Obstetrics & Gynaecology, 44, 574-576.

Journal - Research Article

Losco, G., Sykes, P., Anderson, N., Roberts, H., Fulton, J., & Fraser, H. (2004). Clinical utility of magnetic resonance imaging and the preoperative identification of low risk endometrial cancer. Australian & New Zealand Journal of Obstetrics & Gynaecology, 44(5), 419-422. doi: 10.1111/j.1479-828X.2004.00282.x

Journal - Research Article

Sykes, P., Allen, D., Cohen, C., Scurry, J., & Yeo, D. (2003). Does the density of lymphatic vascular space invasion affect the prognosis of stage Ib and IIA node negative carcinoma of the cervix? International Journal of Gynecological Cancer, 13, 313-316.

Journal - Research Article

Frizelle, F. A., Beasley, S. W., Roake, J. A., & Sykes, P. (2002). Specialisation within the specialty of general surgery; can the potential advantages be realised? New Zealand Medical Journal, 115, 295-298.

Journal - Research Article

Smith, N., Sykes, P., Frizelle, F. A., & McCormick, P. (2002). High-grade vulval intraepithelial neoplasia (VIN3): A retrospective outcome and relationship to squamous cell carcinoma of the vulva 1989-1999. Australian & New Zealand Journal of Obstetrics & Gynaecology, 42, 67-74.

Journal - Research Article

Sykes, P., Nam, S., Wynne, C. J., Anderson, N., North, C. J., Hunter, L., … Fentiman, G. S. (2002). The pre-operative identification of low-risk endometrial cancer: An audit of women treated in the South Island of New Zealand 1998-2000. Australian & New Zealand Journal of Obstetrics & Gynaecology, 42(4), 387-390.

Journal - Research Article

Pather, S., Sykes, P. H., Davis, R., Reid, R. A., & Skjellerup, N. R. (2001). Thromboprophylaxis following caesarean section; hospital protocols are necessary. New Zealand Medical Journal, 114, 339-340.

Journal - Research Article

Simcock, B., Sykes, P. H., & Laney, M. G. (2001). The impact of the National Cervical Screening Programme on the presentation of cancer of the cervix in Canterbury. New Zealand Medical Journal, 114, 378-380.

Journal - Research Article

Foate, J., Begg, E. J., Anderson, T. J., Bagshaw, P. F., Coulter, G., George, P. M., Macleod, S., … Sykes, P. (1999). The Stent report one year on. New Zealand Medical Journal, 112, 278-279.

Journal - Research Article

Sykes, P., & Mulvaney, P. H. (1998). Mesothelial cell hyperplasia in laparoscopy sites may cause difficulties in the diagnosis, staging, and management of ovarian tumours: a case report. International Journal of Gynecological Cancer, 8, 345-348.

Journal - Research Article

Mulvany, N. J., & Sykes, P. (1997). Desmoplastic melanoma of the vulva. Pathology, 29(2), 241-245. doi: 10.1080/00313029700169974

Journal - Research Article

Sykes, P., Quinn, M. A., & Rome, R. (1997). Ovarian tumours of low malignant potential: A retrospective study of 234 patients. International Journal of Gynecological Cancer, 7, 218-226.

Journal - Research Article

Gibson-Helm, M., Slater, T., MacDonald, E. J., Stevenson, K., Adcock, A., Geller, S., … Hibma, M., Sykes, P., … Lawton, B. (2023). Te Ara Waiora-Implementing human papillomavirus (HPV) primary testing to prevent cervical cancer in Aotearoa New Zealand: A protocol for a non-inferiority trial. PLoS ONE, 18(3), e0280643. doi: 10.1371/journal.pone.0280643

Journal - Research Other

Lawton, B., MacDonald, E. J., Storey, F., Stanton, J.-A., Adcock, A., Gibson, M., … King, F., … Watson, H., Bennett, M., Lambert, C. S., Geller, S., Paasi, I., Hibma, M., Sykes, P., Hawkes, D., & Saville, M. (2023). A model for empowering rural solutions for cervical cancer prevention (He Tapu Te Whare Tangata): Protocol for a cluster randomized crossover trial. JMIR Research Protocols, 12, e51643. doi: 10.2196/51643

Journal - Research Other

Yunianto, I., Currie, M., Chitcholtan, K., & Sykes, P. (2023). Potential drug repurposing of ruxolitinib to inhibit the JAK/STAT pathway for the treatment of patients with epithelial ovarian cancer. Journal of Obstetrics & Gynaecology Research, 49, 2563-2574. doi: 10.1111/jog.15761

Journal - Research Other

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