Associate Professor Peter Sykes

2026

Journal - Research Article

Tino, A. B., Faatoese, A., Sykes, P. H., Chitcholtan, K., & Dachs, G. U. (2026). Knowledge and perceptions of gynaecological cancers of Pacific women in Aotearoa New Zealand. New Zealand Medical Journal/Te ara tika o te hauora hapori, 139(1638), 52-67. doi: 10.26635/6965.7292

Koh, S. P., Stephenson, C., Chaplin, J., Ruske, D., Macann, A., Denison, H., Sykes, P., Ji, E., … Tan, S. T. (2026). Economic burden of human papillomavirus-related cancers in New Zealand. BMJ Public Health, 4(2), e003800. doi: 10.1136/bmjph-2025-003800

Tino, A. B., Sykes, P. H., Dachs, G. U., & Chitcholtan, K. (2026). Targeting phosphoinositide 3-kinase to reduce the progression of ovarian cancer cells in a 3D collagen model. Biomolecules, 16, 377. doi: 10.3390/biom16030377

Lawton, B., Gibson, M., Slater, T., Parag, V., Stevenson, K., Adcock, A., … Hibma, M., Sykes, P., … MacDonald, E. J. (2026). Primary cervical screening using a universal offer of human papillomavirus self-testing versus usual care in Aotearoa New Zealand: A cluster-randomised, non-inferiority trial. Lancet Obstetrics, Gynaecology, & Women's Health. Advance online publication. doi: 10.1016/S3050-5038(25)00201-8

Sparkes, N. K., Adcock, A., Slater, T., MacDonald, E. J., Storey, F., Stanton, J.-A., … Hibma, M., Sykes, P., … Lawton, B. (2026). 'Point-of-care-testing is definitely the way to go': Primary healthcare professionals in rural Aotearoa New Zealand talk about point-of-care testing for cervical cancer prevention. Journal of Primary Health Care. Advance online publication. doi: 10.1071/hc25164

Slater, T., Stevenson, K., Adcock, A., Clueard, M.-A., Aperahama, K., Thompson, C., … Hibma, M., Sykes, P., … Lawton, B. (2026). Opportunities to flip the narrative from burden to action for young women joining the National Cervical Screening Programme in Aotearoa New Zealand: A Kaupapa Māori qualitative exploration of experiences and knowledge of cervical screening for 18-30 year olds. Journal of Primary Health Care, 18(2), 141-148. doi: 10.1071/hc25151

2025

Journal - Research Article

Te Whaiti, S., Rose, S. B., Innes, C., Bell, R., Tino, A., McBain, L., & Sykes, P. (2025). “Mana motuhake - I am in charge and have control over my body”: A cross-sectional survey describing Māori participants' experience with HPV primary screening in Aotearoa New Zealand. Journal of Racial & Ethnic Health Disparities. Advance online publication. doi: 10.1007/s40615-025-02725-x

Tino, A. B., Dachs, G. U., Sykes, P. H., & Chitcholtan, K. (2025). Impact of tumor necrosis factor-alpha and lysophosphatidic acid on the behavior of ovarian cancer cells in a three-dimensional collagen hydrogel. Journal of Obstetrics & Gynaecology Research, 51, e70026. doi: 10.1111/jog.70026

Rose, S. B., McBain, L., Bell, R., Innes, C., Te Whaiti, S., Tino, A., & Sykes, P. (2025). Experience of HPV primary screening: A cross-sectional survey of 'Let's test for HPV' study participants in Aotearoa New Zealand. Journal of Primary Health Care, 17(2), 123-133. doi: 10.1071/hc24110

Sykes, P., Innes, C., Bell, R., Nip, J., McMenamin, J., McBain, L., Hudson, B., … Te Whaiti, S., Tino, A., Williman, J., Miller, A., & Lawton, B. (2025). Human papillomavirus (HPV) screening with universal access to vaginal self-testing: Outcomes of an implementation trial. BJOG, 132(9), 1240-1249. doi: 10.1111/1471-0528.18159

Sykes, P., Innes, C., Simcock, B., Lawton, B., & Williman, J. (2025). Realising the promise of HPV vaccination: Data from the national cervical screening and vaccination registers demonstrates the impact of HPV vaccination in Aotearoa New Zealand. Journal of the Royal Society of New Zealand, 55(5), 1271-1283. doi: 10.1080/03036758.2025.2458028

Rose, S. B., McBain, L., Bell, R., Innes, C., Te Whaiti, S., Tino, A., & Sykes, P. (2025). 'Kind of scared but happy something was detected.': Cross-sectional survey of Let's Test for HPV participants to understand perspectives on an HPV detected result. Australian & New Zealand Journal of Obstetrics & Gynaecology, 65(3), 357-365. doi: 10.1111/ajo.13906

Rose, S. B., McBain, L., Garrett, S. M., Bell, R., Innes, C., Te Whaiti, S., Tino, A., & Sykes, P. (2025). 'I felt so empowered, respected and shame free.': Let's test for HPV participants' experience of HPV primary screening. Journal of Primary Health Care, 17(2), 134-145. doi: 10.1071/HC24118

Journal - Research Other

Te Whaiti, S., Sykes, P. H., Scott, N., & Simcock, B. (2025). Let's use an equity framework to improve research, its design, implementation, and community. International Journal of Gynecological Cancer. Advance online publication. doi: 10.1136/ijgc-2024-005938

Conference Contribution - Published proceedings: Abstract

Stanton, J.-A., Lawton, B., Sparkes, N., Paasi, K., McDonald, J., Storey, F., … Hibma, M., … Sykes, P., … Ratapu, M. (2025). Point-of-care testing paired with cervical screening pathways: A study of healthcare delivery in remote Aotearoa. Proceedings of the Infectious Diseases & Pandemic Preparedness Summit. (pp. 50). Retrieved from https://www.teniwha.com

McBain, L., Bell, R., Innes, C., Te Whaiti, S., Tino, A., Sykes, P., & Rose, S. (2025). Experience of HPV primary screening utilising self-testing: A cross-sectional survey of 'Let's test for HPV' study participants in Aotearoa New Zealand. Proceedings of the Society for Academic Primary Care (SAPC) 54th Annual Scientific Meeting. 122. Retrieved from https://sapc.ac.uk

Koh, S., Stephenson, C., Chaplin, J., Ruske, D., Macann, A., Denison, H., Sykes, P., Ji, E., … Tan, S. (2025). The economic burden of HPV-related cancers in New Zealand. ANZ Journal of Surgery, 95(Suppl. 1), QA021P. doi: 10.1111/ans.70068

Aherne, B., Sykes, P., Jaaback, K., Newman, M., Selinger, C., Scurry, J., & van der Griend, R. (2025). Sentinel lymph nodes in early-stage vulval cancer: What are we doing? Pathology, 57(Suppl. 1), (pp. S43). doi: 10.1016/j.pathol.2024.12.172

2024

Journal - Research Article

Stylianou, C. E., Wiggins, G. A. R., Lau, V. L., Dennis, J., Shelling, A. N., Wilson, M., Sykes, P., … Pearson, J., & Walker, L. C. (2024). Germline copy number variants and endometrial cancer risk. Human Genetics, 143, 1481-1498. doi: 10.1007/s00439-024-02707-9

Chitcholtan, K., Singh, M., Tino, A., Garrill, A., & Sykes, P. (2024). Effects of resveratrol on in vivo ovarian cancer cells implanted on the chorioallantoic membrane (CAM) of a chicken embryo model. International Journal of Molecular Sciences, 25, 4374. doi: 10.3390/ijms25084374

Ingamells, S., Bell, R., Nip, J., Innes, C., Te Whaiti, S., Tino, A., McBain, L., McMenamin, J., Hudson, B., … Lawton, B., & Sykes, P. (2024). Perceived barriers to self-collected HPV testing for cervical cancer screening, and knowledge of HPV: A survey of primary healthcare smear-takers across Aotearoa New Zealand. New Zealand Medical Journal/Te ara tika o te hauora hapori, 137(1590), 57-76. Retrieved from https://www.nzmj.org.nz/

Conference Contribution - Published proceedings: Abstract

McBain, L., Innes, C., Bell, R., Sykes, P., & Rose, S. B. (2024). Experience of HPV primary screening utilising self-testing: A cross-sectional survey of 'Lets's test for HPV' study participants in Aotearoa New Zealand. Australian Journal of Primary Health, 30, (pp. 25). doi: 10.1071/PYv30n4abs

2023

Journal - Research Article

Nagao, S., Fujiwara, K., Yamamoto, K., Tanabe, H., Okamoto, A., Takehara, K., … Sykes, P., … Enomoto, T. (2023). Intraperitoneal carboplatin for ovarian cancer - A phase 2/3 trial. NEJM Evidence, 2(5). doi: 10.1056/EVIDoa2200225

Majid, M. A., Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2023). The effects of the obesity-related hormones leptin, insulin, IGF-I and adiponectin on Ishikawa and HEC-1A, MCF-7 and SKOV-3 cancer cell lines. EC Gynaecology, 12(8). Retrieved from https://ecronicon.net/ec_gynaecology

Chitcholtan, K., Dyer, A., & Sykes, P. (2023). Predicting tumour progression of ID-8 syngeneic mouse ovarian cancer with blood biomarkers fo CA-125, IL-6 and VEGF: A prospective laboratory-based study. Clinical & Experimental Obstetrics & Gynaecology, 50(10), 212. doi: 10.31083/j.ceog5010212

Saito, M., Rajesh, A., Innes, C., van der Griend, R., Fitzgerald, P., Simcock, B., Sykes, P., & Hibma, M. (2023). The high-risk human papillomavirus type influences the tissue microenvironment in cervical intraepithelial neoplasia grade 2. Viruses, 15, 1953. doi: 10.3390/v15091953

Mertens, R. C. E., Sykes, P. H., Innes, C. R., Simcock, B. J., & Petrich, S. (2023). Endometrial cancer diagnoses prompted by routine cervical cytology: A retrospective case study. New Zealand Medical Journal/Te ara tika o te hauora hapori, 136(1581), 56-65. Retrieved from https://journal.nzma.org.nz/

Borchowsky, K., Rush, M., Mullally, T., McBain, L., Hudson, B., McMenamin, J., … Sykes, P., & Garrett, S. (2023). Primary care experiences in the 'Let's test for HPV' study: A qualitative analysis. Journal of Primary Health Care, 15(2), 147-154. doi: 10.1071/HC23038

Kumar, D., Moghiseh, M., Chitcholtan, K., Mutreja, I., Lowe, C., Kaushik, A., Butler, A., Sykes, P., Anderson, N., & Raja, A. (2023). LHRH conjugated gold nanoparticles assisted efficient ovarian cancer targeting evaluated via spectral photon-counting CT imaging: A proof-of-concept research. Journal of Materials Chemistry B, 11, 1916-1928. doi: 10.1039/d2tb02416k

Cabasag, C. J., Arnold, M., Rutherford, M., Ferlay, J., Bardot, A., Morgan, E., … Sykes, P., … Soerjomataram, I. (2023). Shifting incidence and survival of epithelial ovarian cancer (1995-2014): A SurvMark-2 study. International Journal of Cancer, 152, 1763-1777. doi: 10.1002/ijc.34403

Journal - Research Other

Lawton, B., MacDonald, E. J., Storey, F., Stanton, J.-A., Adcock, A., Gibson, M., … King, F., … Watson, H., Bennett, M., Lambert, C. S., Geller, S., Paasi, I., Hibma, M., Sykes, P., Hawkes, D., & Saville, M. (2023). A model for empowering rural solutions for cervical cancer prevention (He Tapu Te Whare Tangata): Protocol for a cluster randomized crossover trial. JMIR Research Protocols, 12, e51643. doi: 10.2196/51643

Yunianto, I., Currie, M., Chitcholtan, K., & Sykes, P. (2023). Potential drug repurposing of ruxolitinib to inhibit the JAK/STAT pathway for the treatment of patients with epithelial ovarian cancer. Journal of Obstetrics & Gynaecology Research, 49, 2563-2574. doi: 10.1111/jog.15761

Gibson-Helm, M., Slater, T., MacDonald, E. J., Stevenson, K., Adcock, A., Geller, S., … Hibma, M., Sykes, P., … Lawton, B. (2023). Te Ara Waiora-Implementing human papillomavirus (HPV) primary testing to prevent cervical cancer in Aotearoa New Zealand: A protocol for a non-inferiority trial. PLoS ONE, 18(3), e0280643. doi: 10.1371/journal.pone.0280643

Journal - Professional & Other Non-Research Articles

Allanson, E. R., Burling, M., Simcock, B., Nicklin, J., & Sykes, P. H. (2023). The Australian Society of Gynaecological Oncology Western Pacific Liaison Group [Corners of the world]. International Journal of Gynecological Cancer, 33(11), 1819-1820. doi: 10.1136/ijgc-2023-004845

2022

Journal - Research Article

Saito, M., Rajesh, A., Innes, C., van der Griend, R., Fitzgerald, P., Simcock, B., Sykes, P., & Hibma, M. (2022). Blimp-1 is a prognostic indicator for progression of cervical intraepithelial neoplasia grade 2. Journal of Cancer Research & Clinical Oncology, 148, 1991-2002. doi: 10.1007/s00432-022-03993-4

Dunn, E., Chitcholtan, K., Sykes, P., & Garrill, A. (2022). The anti-proliferative effect of PI3K/mTOR and ERK inhibition in monolayer and three-dimensional ovarian cancer cell models. Cancers, 14, 395. doi: 10.3390/cancers14020395

Sarwar, M., Sykes, P. H., Chitcholtan, K., & Evans, J. J. (2022). Collagen I dysregulation is pivotal for ovarian cancer progression. Tissue & Cell, 74, 101704. doi: 10.1016/j.tice.2021.101704

Sykes, P. H., Simcock, B. J., Innes, C. R., Harker, D., Williman, J. A., Whitehead, M., van der Griend, R. A., … Hibma, M., … Petrich, S., … Sadler, L. (2022). Predicting regression of cervical intraepithelial neoplasia grade 2 in women under 25 years. American Journal of Obstetrics & Gynecology, 226, 222.e1-222.e13. doi: 10.1016/j.ajog.2021.09.009

Journal - Research Other

Taghavi, K., Lamb, J., MacNab, H., Innes, C., Peddie, D., Harker, D., Williman, J., Sykes, P., & Simcock, B. (2022). Patient choice may improve adherence to follow-up in cervical screening: A randomised-control trial. New Zealand Medical Journal, 135(1550), 134-144. Retrieved from https://journal.nzma.org.nz/

Boo, M., Sykes, P., & Simcock, B. (2022). Use of direct oral anticoagulants for postoperative venous thromboembolism prophylaxis after surgery for gynecologic malignancies. International Journal of Gynecological Cancer, 32, 189-194. doi: 10.1136/ijgc-2021-003006

Conference Contribution - Verbal presentation and other Conference outputs

Saito, M., Rajesh, A., Innes, C., van der Griend, R., Fitzgerald, P., Simcock, B., Sykes, P., & Hibma, M. (2022, August). The immune microenvironment in progression and regression of cervical intraepithelial neoplasia grade 2. Verbal presentation at the Cancer Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.

2021

Journal - Research Article

Edmonson, R. J., O'Connell, R. L., Banerjee, S., Mileshkin, L., Sykes, P., Beale, P., … on behalf of PARAGON Investigators. (2021). Phase 2 study of anastrozole in rare cohorts of patients with estrogen receptor/progesterone receptor positive leiomyosarcomas and carcinosarcomas of the uterine corpus: The PARAGON trial (ANZGOG 0903). Gynecologic Oncology, 163, 524-530. doi: 10.1016/j.ygyno.2021.09.010

Janda, M., Robledo, K. P., Gebski, V., Armes, J. E., Alizart, M., Cummings, M., … Sykes, P., … Obermair, A. (2021). Complete pathological response following levonorgestrel intrauterine device in clinically stage 1 endometrial adenocarcinoma: Results of a randomized clinical trial. Gynecologic Oncology, 161(1), 143-151. doi: 10.1016/j.ygyno.2021.01.029

Sarwar, M., Sykes, P. H., Chitcholtan, K., & Evans, J. J. (2021). Deciphering biophysical modulation in ovarian cancer cells. Cell Biochemistry & Biophysics, 79, 375-386. doi: 10.1007/s12013-020-00964-9

2020

Journal - Research Article

Goyani, A. D., Innes, C. R., Simcock, B. J., Harker, D., Dudley, N. M., Eva, L., Bergzoll, C., MacNab, H., & Sykes, P. H. (2020). Trends in the diagnosis of high-grade cervical abnormalities in young women in the post-vaccination era. New Zealand Medical Journal, 133(1524), 50-63. Retrieved from https://www.nzma.org.nz/journal

Cohen, P. A., Leung, Y., Anderson, L., van der Griend, R., Chivers, P., Bilic, S., … Harker, D., … Simcock, B., … Sykes, P., … Wrede, C. D. H. (2020). Excisional treatment comparison for in situ endocervical adenocarcinoma (EXCISE): A phase 2 pilot randomized controlled trial to compare histopathological margin status, specimen size and fragmentation after loop electrosurgical excision procedure and cold knife cone biopsy. Gynecologic Oncology, 159, 623-629. doi: 10.1016/j.ygyno.2020.09.053

Norell, C. H., Butler, J., Farrell, R., Altman, A., Bentley, J., Cabasag, C. J., … Sykes, P. H., … Harrison, S. (2020). Exploring international differences in ovarian cancer treatment: A comparison of clinical practice guidelines and patterns of care. International Journal of Gynecological Cancer, 30, 1748-1756. doi: 10.1136/ijgc-2020-001403

Chitcholtan, K., Harker, D., Simcock, B., & Sykes, P. (2020). Sensitivity of EGFR/HER-2 positive cells isolated from ascitic fluid of advanced ovarian cancer patients to EGFR/HER-2 inhibitors. Applied Sciences, 10(7), 2343. doi: 10.3390/app10072343

Dempster-Rivett, K., Innes, C. R., Simcock, B. J., Harker, D., Williman, J. A., Van Der Griend, R. A., Whitehead, M., Hibma, M., … Petrich, S., Faherty, J., … Sykes, P. H. (2020). Evaluation of guidelines for observational management of cervical intraepithelial neoplasia 2 in young women. American Journal of Obstetrics & Gynecology, 223, 408.e1-408.e11. doi: 10.1016/j.ajog.2020.02.029

Cabasag, C. J., Butler, J., Arnold, M., Rutherford, M., Bardot, A., Ferlay, J., … Sykes, P., … Soerjomataram, I. (2020). Exploring variations in ovarian cancer survival by age and stage (ICBP SurvMark-2): A population-based study. Gynecologic Oncology, 157, 234-244. doi: 10.1016/j.ygyno.2019.12.047

Innes, C. R. H., Williman, J. A., Simcock, B. J., Hider, P., Sage, M., Dempster-Rivett, K., … Sykes, P. H. (2020). Impact of human papillomavirus vaccination on rates of abnormal cervical cytology and histology in young New Zealand women. New Zealand Medical Journal, 133(1508), 72-84. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Other

Sarwar, M., Sykes, P., & Evans, J. J. (2020). A doctrine of ovarian cancer translational research needs revisiting. International Journal of Cancer Management, 13(8), e105436. doi: 10.5812/ijcm.105436

Butler, J., Finley, C., Norell, C. H., Harrison, S., Bryant, H., Achiam, M. P., … Sykes, P., & Thomas, R. (2020). New approaches to cancer care in a COVID-19 world. Lancet Oncology, 21(7), e339-e340. doi: 10.1016/S1470-2045(20)30340-5

Sarwar, M., Sykes, P. H., Chitcholtan, K., & Evans, J. J. (2020). Extracellular biophysical environment: Guilty of being a modulator of drug sensitivity in ovarian cancer cells. Biochemical & Biophysical Research Communications, 527(1), 180-186. doi: 10.1016/j.bbrc.2020.04.107

2019

Journal - Research Article

Yeoh, S., Simcock, B., Innes, C., Mclachlan, J., Harker, D., & Sykes, P. (2019). Trends in the overall survival rates in women with advanced ovarian cancer in a single tertiary centre in New Zealand. Australian & New Zealand Journal of Obstetrics & Gynaecology, 59, 861-866. doi: 10.1111/ajo.13076

Tang, M., O'Connell, R. L., Amant, F., Beale, P., McNally, O., Sjoquist, K. M., … Sykes, P., … Friedlander, M. (2019). PARAGON: A phase II study of anastrozole in patients with estrogen receptor-positive recurrent/metastatic low-grade ovarian cancers and serous borderline ovarian tumors. Gynecologic Oncology, 154, 531-538. doi: 10.1016/j.ygyno.2019.06.011

Cohen, P. A., Powell, A., Böhm, S., Gilks, C. B., Stewart, C. J. R., Meniawy, T. M., … van der Griend, R., … the HGSC CRS Collaborative Network, including Simcock, B., Sykes, P., Vaughan, M. M., & Singh, N. (2019). Pathological chemotherapy response score is prognostic in tubo-ovarian high-grade serous carcinoma: A systematic review and meta-analysis of individual patient data. Gynecologic Oncology, 154, 441-448. doi: 10.1016/j.ygyno.2019.04.679

Ekeroma, A. J., Naik, S., & Sykes, P. (2019). Systematic review of effective cervical cancer treatments in Small Island Developing States: A narrative synthesis. Pacific Journal of Reproductive Health, (8), 462-474. doi: 10.18313/pjrh.2019.906

Sykes, P., Eva, L., van der Griend, R., McNally, O., Blomfield, P., Brand, A., … Petrich, S., Kenwright, D., … Innes, C., Harker, D., … Simcock, B. (2019). Pathological process has a crucial role in sentinel node biopsy for vulvar cancer. Gynecologic Oncology, 153, 292-296. doi: 10.1016/j.ygyno.2019.02.012

Fraser, K., Tan, A. L., Innes, C., Stephens, R., Tristram, A., Petrich, S., Lintott, C., Sykes, P. H., … Simcock, B. (2019). Patterns of referral and uptake of BReast CAncer (BRCA) gene testing of eligible women with ovarian cancer in New Zealand. New Zealand Medical Journal, 132(1490), 26-35. Retrieved from https://www.nzma.org.nz/journal

Adcock, A., Cram, F., Lawton, B., Geller, S., Hibma, M., Sykes, P., … Hart, S. (2019). Acceptability of self-taken vaginal HPV sample for cervical screening among an under-screened Indigenous population. Australian & New Zealand Journal of Obstetrics & Gynaecology, 59, 301-307. doi: 10.1111/ajo.12933

Sarwar, M., Sykes, P. H., Chitcholtan, K., Alkaisi, M. M., & Evans, J. J. (2019). The extracellular topographical environment influences ovarian cancer cell behaviour. Biochemical & Biophysical Research Communications, 508, 1188-1194. doi: 10.1016/j.bbrc.2018.12.067

Journal - Research Other

Evans, J. J., Alkaisi, M. M., & Sykes, P. H. (2019). Tumour initiation: A discussion on evidence for a "load-trigger" mechanism [Hypothesis]. Cell Biochemistry & Biophysics, 77, 293-308. doi: 10.1007/s12013-019-00888-z

Conference Contribution - Published proceedings: Abstract

Bowden, V., Cuddihy, S., Yeoh, S., Innes, C., van der Griend, R., Simcock, B., Sykes, P., & Harker, D. (2019). Audit of intraoperative ovarian frozen section accuracy in a single tertiary centre. Australian & New Zealand Journal of Obstetrics & Gynaecology, 59(Suppl. 1), (pp. 53-54). doi: 10.1111/ajo.13067

2018

Journal - Research Article

Innes, C. R., Sykes, P. H., Harker, D., Williman, J. A., Van der Griend, R. A., Whitehead, M., Hibma, M., … Petrich, S., Faherty, J., … Simcock, B. J. (2018). Changes in human papillomavirus genotypes associated with cervical intraepithelial neoplasia grade 2 lesions in a cohort of young women (2013–2016). Papillomavirus Research, 6, 77-82. doi: 10.1016/j.pvr.2018.10.010

Hider, P., Dempster-Rivett, K., Williman, J., Dempster-Rivett, M., Sadler, L., McLeod, M., Miller, A., & Sykes, P. (2018). A review of cervical cancer occurrences in New Zealand 2008–2012. New Zealand Medical Journal, 131(1472), 53-63. Retrieved from https://www.nzma.org.nz/journal

Hassan, W., Chitcholtan, K., Sykes, P., & Garrill, A. (2018). Ascitic fluid from advanced ovarian cancer patients compromises the activity of receptor tyrosine kinase inhibitors in 3D cell clusters of ovarian cancer cells. Cancer Letters, 420, 168-181. doi: 10.1016/j.canlet.2018.02.013

Evans, G. E., Phillipson, G. T. M., Sykes, P. H., McNoe, L. A., Print, C. G., & Evans, J. J. (2018). Does the endometrial gene expression of fertile women vary within and between cycles? Human Reproduction, 33(3), 452-463. doi: 10.1093/humrep/dex385

Conference Contribution - Published proceedings: Abstract

Tino, A., Dachs, G., Sykes, P., Evans, J., & Chitcholtan, K. (2018). Ovarian cancer cell lines grown in a three dimensional collagen model respond differentially to lysophosphatidic acid and tumour necrosis factor-alpha. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Sarwar, M., Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2018). Microenvironment biophysics: It is vital to tumour cell behaviour including resistance to chemotherapy. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Conference Contribution - Poster Presentation (not in published proceedings)

Sarwar, M., Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2018, August). Unseen to be seen: A hidden microenvironment regulates ovarian cancer cell behaviour. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Chitcholtan, K., Harker, D., Simcock, B., & Sykes, P. (2018, August). Inhibition of EGFR/HER-2 affects growth of ascitic ovarian cancer cells in vitro study. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Evans, J. J., Alkaisi, M. M., & Sykes, P. H. (2018, August). An alliance of biophysics, biochemistry and genetics initiates cancers. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2017

Journal - Research Article

Janda, M., Gebski, V., Davies, L. C., Forder, P., Brand, A., Hogg, R., … Sykes, P., … Simcock, B., … Obermair, A. (2017). Effect of total laparoscopic hysterectomy vs total abdominal hysterectomy on disease-free survival among women with stage 1 endometrial cancer: A randomised clinical trial. JAMA, 317(12), 1224-1233. doi: 10.1001/jama.2017.2068

Kumar, D., Mutreja, I., Chitcholtan, K., & Sykes, P. (2017). Cytotoxicity and cellular uptake of different sized gold nanoparticles in ovarian cancer cells. Nanotechnology, 28, 475101. doi: 10.1088/1361-6528/aa935e

Jamieson, A., Sykes, P., Eva, L., Bergzoll, C., & Simcock, B. (2017). Subtypes of stage IV ovarian cancer: Response to treatment and patterns of disease recurrence. Gynecologic Oncology, 146(2), 273-278. doi: 10.1016/j.ygyno.2017.05.023

Lindemann, K., Kok, P.-S., Stockler, M., Sykes, P., & Brand, A. (2017). Enhanced recovery after surgery for suspected ovarian malignancy: A survey of perioperative practice among gynecologic oncologists in Australia and New Zealand to inform a clinical trial. International Journal of Gynecological Cancer, 27(5), 1046-1050. doi: 10.1097/igc.0000000000000982

Taghavi, K., Morell, S., Lamb, J., MacNab, H., Innes, C., Coffey, K., Williman, J., Simcock, B., & Sykes, P. (2017). Initial observation of CIN2 does not appear to reduce quality of life in women under 25 years of age. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(4), 473-478. doi: 10.1111/ajo.12633

Tan, L. H., Sykes, P. H., Alkaisi, M. M., & Evans, J. J. (2017). Cell-like features imprinted in the physical nano- and micro-topography of the environment modify the responses to anti-cancer drugs of endometrial cancer cells. Biofabrication, 9(1), 015017. doi: 10.1088/1758-5090/aa5c9a

Journal - Research Other

Cohen, P., Brand, A., Sykes, P., Wrede, D. C. H., McNally, O., Eva, L., … Stoyles, P. (2017). Excisional treatment in women with cervical adenocarcinoma in situ (AIS): A prospective randomised controlled non-inferiority trial to compare AIS persistence/recurrence after loop electrosurgical excision procedure with cold knife cone biopsy: Protocol for a pilot study. BMJ Open, 7, e017576. doi: 10.1136/bmjopen-2017-017576

Conference Contribution - Published proceedings: Abstract

Adams, F., Sykes, P., Simcock, B., MacNab, H., Innes, C., & Scowcroft, H. (2017). Rates of high grade histology (CIN grade 2 or 3) in women over 30 years referred with low grade cervical cytology and the role of hrHPV. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(Suppl. 1), (pp. 23-24). doi: 10.1111/ajo.12724

Harlow, K., Sykes, P., & De Silva, S. (2017). Attempted implementation of the new Ministry of Health High Suspicion of Cancer definitions for gynaecological malignancies on referrals from primary care to a tertiary gynaecology service in New Zealand: A prospective audit. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(Suppl. 1), (pp. 47). doi: 10.1111/ajo.12725

Yunianto, I., Chitcholtan, K., Currie, M., & Sykes, P. (2017). JAK/STAT pathway inhibition for the treatment of ovarian cancer. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 98). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html

Simcock, B., Innes, C., Sykes, P., Harker, D., Williman, J., van der Griend, R., … Bergzoll, C., Petrich, S., & Lawton, B. (2017). Changing face of HPV in CIN2 in young New Zealand women. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(Suppl. 1), (pp. 62). doi: 10.1111/ajo.12725

Innes, C., Sykes, P., Williman, J., Dempster-Rivett, K., Simcock, B., Hider, P., & Lawton, B. (2017). Impact of HPV vaccination on rates of high grade cervical abnormalities in young NZ women: Register data matching study. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(Suppl. 1), (pp. 6). doi: 10.1111/ajo.12723

Dempster-Rivett, K., Sykes, P., Williman, J., Hider, P., & Dempster-Rivett, M. (2017). Review of cervical cancer cases in New Zealand from 2008-2012 in relation to cervical screening history. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(Suppl. 1), (pp. 40). doi: 10.1111/ajo.12725

Raja, A. Y., Moghiesh, M., Kumar, D., Sykes, P., Butler, A. P., & Anderson, N. (2017). Effect of size and concentration of gold nanoparticles on spectral CT imaging of cancer cells. Proceedings of the 8th International Conference on Advanced Materials and Nanotechnology (AMN8). (pp. 105). Retrieved from http://confer.co.nz/amn8/

Conference Contribution - Verbal presentation and other Conference outputs

Simcock, B. J., Sykes, P. H., Innes, C. R. H., Lawton, B., Dudley, N., & van der Griend, R. (2017, March). CIN3MA: Observational management of CIN3 in women under 25 years. Verbal presentation at the Australian Society for Colposcopy and Cervical Pathology (ASCCP) XXV^th Scientific Meeting, Sydney, Australia.

Sykes, P., Innes, C. R. H., van der Griend, R., Fitzgerald, P., & Simcock, B. (2017, March). Decreasing prevalence of HPV16 & 18 genotypes in young New Zealand women with biopsy-diagnosed CIN2. Verbal presentation at the Australian Society for Colposcopy and Cervical Pathology (ASCCP) XXV^th Scientific Meeting, Sydney, Australia.

Dempster-Rivett, K., Innes, C. R., Simcock, B., & Sykes, P. (2017, March). The reliability of colposcopy and cervical cytology in observational management of CIN 2 in women under 25. Verbal presentation at the Australian Society for Colposcopy and Cervical Pathology (ASCCP) XXV^th Scientific Meeting, Sydney, Australia.

Sarwar, M., Chitcholtan, K., Alkaisi, M. M., Sykes, P. H., & Evans, J. J. (2017, September). The cell-environment handshake: An interaction that regulates gene expression. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2016

Journal - Research Article

Tino, A. B., Chitcholtan, K., Sykes, P. H., & Garrill, A. (2016). Resveratrol and acetyl-resveratrol modulate activity of VEGF and IL-8 in ovarian cancer cell aggregates via attenuation of the NF-κB protein. Journal of Ovarian Research, 9, 84. doi: 10.1186/s13048-016-0293-0

Hassan, W., Chitcholtan, K., Sykes, P., & Garrill, A. (2016). A combination of two receptor tyrosine kinase inhibitors, canertinib and PHA665752 comprises ovarian cancer cell growth in 3D cell models. Oncology & Therapy, 4(2), 257-274. doi: 10.1007/s40487-016-0031-1

Kumar, D., Mutreja, I., & Sykes, P. (2016). Seed mediated synthesis of highly mono-dispersed gold nanoparticles in the presence of hydroquinone. Nanotechnology, 27, 355601. doi: 10.1088/0957-4484/27/35/355601

Stravens, M., Short, J., Johnson, K., Simcock, B., Shand, B., McGeoch, G., & Sykes, P. (2016). Management of postmenopausal bleeding by general practitioners in a community setting: An observational study. New Zealand Medical Journal, 129(1434), 59-68. Retrieved from http://www.nzma.org.nz/journal

Journal - Research Other

Sykes, P., Innes, C., Harker, D., Whitehead, M., van der Griend, R., Lawton, B., Hibma, M., … Petrich, S., Faherty, J., Bergzoll, C., … Parker, C., Sadler, L., & Simcock, B. (2016). Observational management of CIN 2 in young women: A prospective multicenter trial. Journal of Lower Genital Tract Disease, 20(4), 343-347. doi: 10.1097/lgt.0000000000000244

Conference Contribution - Published proceedings: Abstract

Saito, M., Budhwani, M., Coffey, K., Sykes, P., & Hibma, M. (2016). Immunological markers of persistence & regression in cervical intraepithelial neoplasia grade 2 in women under 25. European Journal of Immunology, 46(Suppl. 1), (pp. 217-218). doi: 10.1002/eji.201670200

2015

Journal - Research Article

Hogg, S. J., Chitcholtan, K., Hassan, W., Sykes, P. H., & Garrill, A. (2015). Resveratrol, acetyl-resveratrol, and polydatin exhibit antigrowth activity against 3D cell aggregates of the SKOV-3 and OVCAR-8 ovarian cancer cell lines. Obstetrics & Gynecology International, 2015, 279591. doi: 10.1155/2015/279591

Tan, L. H., Sykes, P. H., Alkaisi, M. M., & Evans, J. J. (2015). The characteristics of Ishikawa endometrial cancer cells are modified by substrate topography with cell-like features and the polymer surface. International Journal of Nanomedicine, 10, 4883-4895. doi: 10.2147/ijn.s86336

Hogg, S. J., Evans, J. J., Sykes, P. H., & Chitcholtan, K. (2015). A method to investigate the anti-metabolic activity of anti-cancer agents on ovarian cancer cells cultured in a 96-well high throughput format. Journal of Ovarian Research, 8, 43. doi: 10.1186/s13048-015-0172-0

Wilkinson, T. M., Sykes, P. H. H., Simcock, B., & Petrich, S. (2015). Recurrence of high-grade cervical abnormalities following conservative management of cervical intraepithelial neoplasia grade 2. American Journal of Obstetrics & Gynecology, 212(6), 769.e1-769.e7. doi: 10.1016/j.ajog.2015.01.010

Slatter, T. L., Hsia, H., Samaranayaka, A., Sykes, P., Clow, W., Devenish, C. J., … Royds, J. A., … Hung, N. A. (2015). Loss of ATRX and DAXX expression identifies poor prognosis for smooth muscle tumours of uncertain malignant potential and early stage uterine leiomyosarcoma. Journal of Pathology: Clinical Research, 1(2), 95-105. doi: 10.1002/cjp2.11

Journal - Research Other

Taghavi, K., Sykes, P., Innes, C., Gibbs, D., Hunter, L. A., McBurnie, W., & Simcock, B. (2015). Wrong place at the wrong time: A case of cervical embryonal rhabdomyosarcoma in pregnancy. Gynecologic Oncology Reports, 12, 77-79. doi: 10.1016/j.gore.2015.04.001

Conference Contribution - Verbal presentation and other Conference outputs

Tan, L. H., Sykes, P. H., Alkaisi, M. M., & Evans, J. J. (2015, August-September). Functioning of Ishikawa cancer cells is dependent on the physical microenvironment, which can modify genetic activities. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2014

Journal - Research Article

Lawton, B., Filoche, S. K., Rose, S. B., Stanley, J., Garrett, S., Robson, B., Brown, S., & Sykes, P. (2014). Uterine cancer: Exploring access to services in the public health system. Australian & New Zealand Journal of Obstetrics & Gynaecology, 54(5), 457-461. doi: 10.1111/ajo.12237

Amant, F., Floquet, A., Friedlander, M., Kristensen, G., Mahner, S., Nam, E. J., … Sykes, P., … Seddon, B. (2014). Gynecological Cancer InterGroup (GCIG) consensus review for endometrial stromal sarcoma. International Journal of Gynecological Cancer, 24(9, Suppl. 3), S67-S72. doi: 10.1097/igc.0000000000000205

Sykes, P., Gopala, K., Tan, A. L., Kenwright, D., Petrich, S., Molijn, A., & Chen, J. (2014). Type distribution of human papillomavirus among adult women diagnosed with invasive cervical cancer (stage 1b or higher) in New Zealand. BMC Infectious Diseases, 14, 374. doi: 10.1186/1471-2334-14-374

Evans, G. E., Martínez-Conejero, J. A., Phillipson, G. T. M., Sykes, P. H., Sin, I. L., Lam, E. Y. N., … Evans, J. J. (2014). In the secretory endometria of women, luminal epithelia exhibit gene and protein expressions that differ from those of glandular epithelia. Fertility & Sterility, 102(1), 307-317. doi: 10.1016/j.fertnstert.2014.04.005

Journal - Research Other

Sykes, P. (2014). [Review of the book The rise and fall of National Women’s Hospital: A history]. New Zealand Medical Journal, 127(1394). Retrieved from http://www.nzma.org.nz/journal

Conference Contribution - Published proceedings: Abstract

Evans, J. J., Tan, L. H., Sykes, P. H., & Alkaisi, M. M. (2014). Topography of the microenvironment determines cancer cell behaviour. Endocrine Reviews, 35(3, Suppl.), MON-315. Retrieved from http://press.endocrine.org/series/endo-meetings

Evans, J. J., Majid, M., Chitcholtan, K., & Sykes, P. H. (2014). Responses of proliferation and VEGF secretion by Ishikawa cells are not parallel when exposed to leptin and adiponectin. Endocrine Reviews, 35(3, Suppl.), MON-0306. Retrieved from http://press.endocrine.org/series/endo-meetings

Conference Contribution - Poster Presentation (not in published proceedings)

Chitcholtan, K., Evans, J., & Sykes, P. (2014, November). Inhibition of EGFR/HER-2 affects growth of ascitic ovarian cancer cells in vitro study. Poster session presented at the 15th Biennial Meeting of the International Gynecologic Cancer Society (IGCS), Melbourne, Australia.

Majid, M. A., Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2014, November). Growth factors modulate endometrium cancer cells' proliferation and VEGF secretion. Poster session presented at the 15th Biennial Meeting of the International Gynecologic Cancer Society (IGCS), Melbourne, Australia.

2013

Chapter in Book - Other

Sykes, P. (2013). Obstetrics and Gynaecology. In P. Joyce, G. Nicholls, K. Thomas & T. Wilkinson (Eds.), The Christchurch experience: 40 years of research and teaching. (pp. 33-37). Christchurch, New Zealand: University of Otago.

Journal - Research Article

Kang, M. Y., Sykes, P., Herbison, P., & Petrich, S. (2013). Retrospective analysis on timeframes of referral, diagnosis and treatment of patients with endometrial carcinomas in Dunedin Hospital, 2008–2011. New Zealand Medical Journal, 126(1384). Retrieved from http://www.nzma.org.nz/journal

Chitcholtan, K., Asselin, E., Parent, S., Sykes, P. H., & Evans, J. J. (2013). Differences in growth properties of endometrial cancer in three dimensional (3D) culture and 2D cell monolayer. Experimental Cell Research, 319(1), 75-87. doi: 10.1016/j.yexcr.2012.09.012

Conference Contribution - Verbal presentation and other Conference outputs

Tan, T., Sykes, P. H., Alkaisi, M. M., & Evans, J. J. (2013, August). Behaviour of cancer cells on a surface imprinted with their own features. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Majid, M., Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2013, August). Adipokines alter behaviour of endometrial cancer cells. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2012

Journal - Research Article

Kondalsamy-Chennakesavan, S., Janda, M., Gebski, V., Baker, J., Brand, A., Hogg, R., … Sykes, P., … Simcock, B., … Obermair, A. (2012). Risk factors to predict the incidence of surgical adverse events following open or laparoscopic surgery for apparent early stage endometrial cancer: Results from a randomised controlled trial. European Journal of Cancer, 48(14), 2155-2162. doi: 10.1016/j.ejca.2012.03.013

Obermair, A., Janda, M., Baker, J., Kondalsamy-Chennakesavan, S., Brand, A., Hogg, R., … Sykes, P., … Simcock, B., … Gebski, V. (2012). Improved surgical safety after laparoscopic compared to open surgery for apparent early stage endometrial cancer: Results from a randomised controlled trial. European Journal of Cancer, 48(8), 1147-1153. doi: 10.1016/j.ejca.2012.02.055

Lawton, B. A., Rose, S. B., Pullon, S., Stanley, J., Garrett, S., Sykes, P., Cormack, D., Robson, B., Langdana, F., Cooper, A., & Filoche, S. K. (2012). The impact of outpatient booking systems on waiting times for investigation of suspected cancer: The case of post-menopausal bleeding. Clinical Ovarian & Other Gynecologic Cancer, 5(2), 87-93. doi: 10.1016/j.cogc.2013.06.001

Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2012). The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer. Journal of Translational Medicine, 10(1), 38-53. doi: 10.1186/1479-5876-10-38

Sykes, P., Vaughan, M., Chrystal, K., Ehrenberg, N., Hefford, M., Hutchings, S., … Ngan Kee, D. (2012). Providing care for women with gynaecological malignancy: The need for a coordinated national approach. New Zealand Medical Journal, 125(1360). Retrieved from http://www.nzma.org.nz/journal

Kondalsamy-Chennakesavan, S., Yu, C., Kattan, M. W., Leung, Y., Sykes, P., Nascimento, M., … Obermair, A. (2012). Nomograms to predict isolated loco-regional or distant recurrence among women with uterine cancer. Gynecologic Oncology, 125(3), 520-525. doi: 10.1016/j.ygyno.2012.02.022

Evans, G. E., Martínez-Conejero, J. A., Phillipson, G. T. M., Simón, C., McNoe, L. A., Sykes, P. H., … Evans, J. J. (2012). Gene and protein expression signature of endometrial glandular and stromal compartments during the window of implantation. Fertility & Sterility, 97(6), 1365-1373. doi: 10.1016/j.fertnstert.2012.03.007

Evans, J. J., Chitcholtan, K., Dann, J. M., Guilford, P., Harris, G., Lewis, L. K., Nagase, J., … Sykes, P. H. (2012). Adrenomedullin interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades. Gynecologic Oncology, 125(1), 214-219. doi: 10.1016/j.ygyno.2011.12.429

Journal - Research Other

Walker, N. H., Sabanli, M., Sykes, P. H., Russell, P., & Perez, D. (2012). Successful reproductive outcome following treatment of advanced small cell carcinoma of the ovary. Gynecologic Oncology Reports, 2(3), 115-117. doi: 10.1016/j.gynor.2012.06.001

Sykes, P. H., McAllum, B. E., Simcock, B., & Sadler, L. (2012). [Reply to letter to the editor Initial diagnosis of CIN 2—should patients be managed expectatively?]. American Journal of Obstetrics & Gynecology, 206(3), e11-e12. doi: 10.1016/j.ajog.2011.11.004

Conference Contribution - Published proceedings: Abstract

Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2012). Three-dimensional (3D) micro-environments may provide cell templates for drugs that are different from those of two dimensions (2D). Endocrine Reviews, 33(3, Suppl.), SAT-271. Retrieved from http://press.endocrine.org/series/endo-meetings

Sykes, P., Gopala, K., & Chen, J. (2012). Prevalence and type distribution of human papillomavirus (HPV) in New Zealand women with invasive cervical cancer. International Journal of Gynecological Cancer, 22(8, Suppl. 3), (pp. E767). doi: 10.1097/01.IGC.0000422085.58592.d3

2011

Journal - Research Article

McAllum, B., Sykes, P. H. H., Sadler, L., MacNab, H., Simcock, B. J., & Mekhail, A. K. (2011). Is the treatment of CIN 2 always necessary in women under 25? American Journal of Obstetrics & Gynecology, 205(5), 478.e1-478.e7. doi: 10.1016/j.ajog.2011.06.069

McLeod, M., Cormack, D., Harris, R., Robson, B., Sykes, P., & Crengle, S. (2011). Achieving equitable outcomes for Māori women with cervical cancer in New Zealand: Health provider views. New Zealand Medical Journal, 124(1334). Retrieved from http://journal.nzma.org.nz/journal/124-1334/4661/content.pdf

Obermair, A., Mileshkin, L., Bolz, K., Kondalsamy-Chennakesavan, S., Cheuk, R., Vasey, P., … Sykes, P., & Janda, M. (2011). Prospective, non-randomized phase 2 clinical trial of carboplatin plus paclitaxel with sequential radical pelvic radiotherapy for uterine papillary serous carcinoma. Gynecologic Oncology, 120(2), 179-184. doi: 10.1016/j.ygyno.2010.10.039

Conference Contribution - Published proceedings: Abstract

Flanagan, L., Sykes, P., Miller, A., & Hibma, M. (2011). Antigen presenting cells in the human papillomavirus-induced tumour microenvironment. New Zealand Medical Journal, 124(1346). Retrieved from http://journal.nzma.org.nz/journal/124-1346/4980/content.pdf

Kuiper, C., Molenaar, I. G. M., Dachs, G. U., Currie, M. J., Sykes, P. H., & Vissers, M. C. M. (2011). Low ascorbate levels are associated with high hypoxia-inducible factor-1 activity and a more aggressive tumor phenotype in endometrial cancer. Clinical and Experimental Metastasis. 28(2), (pp. 175). doi: 10.1007/s10585-010-9361-9

Conference Contribution - Verbal presentation and other Conference outputs

Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2011, August). Responses of cancer cells, to doxorubicon and cisplatin, are different in 3D and 2D environments. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2010

Journal - Research Article

Janda, M., Gebski, V., Brand, A., Hogg, R., Jobling, T. W., Land, R., … Sykes, P., … Obermair, A. (2010). Quality of life after total laparoscopic hysterectomy versus total abdominal hysterectomy for stage I endometrial cancer (LACE): A randomised trial. Lancet Oncology, 11(8), 772-780. doi: 10.1016/S1470-2045(10)70145-5

Smart, O. C., Sykes, P., McNab, H., & Jennings, L. (2010). Testing for high risk human papilloma virus in the initial follow-up of women treated for high-grade squamous intraepithelial lesions. Australian & New Zealand Journal of Obstetrics & Gynaecology, 50(2), 164-167. doi: 10.1111/j.1479-828X.2009.01132.x

Kuiper, C., Molenaar, I. G. M., Dachs, G. U., Currie, M. J., Sykes, P. H., & Vissers, M. C. M. (2010). Low ascorbate levels are associated with increased hypoxia-inducible factor-1 activity and an aggressive tumor phenotype in endometrial cancer. Cancer Research, 70(14), 5749-5758. doi: 10.1158/0008-5472.CAN-10-0263

McLeod, M., Harris, R., Purdie, G., Cormack, D., Robson, B., Sykes, P., Crengle, S., Iupati, D., & Walker, N. (2010). Improving survival disparities in cervical cancer between Māori and non-Māori women in New Zealand: A National Retrospective Cohort Study. Australian & New Zealand Journal of Public Health, 34(2), 193-199. doi: 10.1111/j.1753-6405.2010.00506.x

Priest, P., Sadler, L., Sykes, P., Marshall, R., Peters, J., & Crengle, S. (2010). Determinants of inequalities in cervical cancer stage at diagnosis and survival in New Zealand. Cancer Causes & Control, 21, 209-214. doi: 10.1007/s10552-009-9451-7

Conference Contribution - Published proceedings: Abstract

Chitcholtan, K., Evans, J., & Sykes, P. H. (2010). Multicellular spheroids of epithelial endometrial cancer: Characterisation and application for anti-cancer drug screening. Proceedings of the International Gynecologic Cancer Society (IGCS) 13th Biennial Meeting. Retrieved from http://www.igcs.org/index.html

Obermair, A., Gebski, V., Nicklin, J., Perrin, L., Jobling, T., Manolitsas, T., … Sykes, P., … Janda, M. (2010). The laparoscopic approach to carcinoma of the endometrium (LACE) randomized trial: Adverse events comparing total laparoscopic hysterectomy versus total abdominal hysterectomy. International Journal of Gynecological Cancer, 20(Suppl. 2). Retrieved from http://journals.lww.com/ijgc/Documents/IGCS%2013%20Meeting%20Abstracts,%20Prague.pdf

2009

Journal - Research Article

Su, H. Y., & Sykes, P. H. (2009). Waiting times for gynaecological cancer surgery. New Zealand Medical Journal, 122(1305). Retrieved from http://journal.nzma.org.nz/journal/122-1305/3854/content.pdf

Dann, J. M., Sykes, P. H., Mason, D. R., & Evans, J. J. (2009). Regulation of Vascular Endothelial Growth Factor in endometrial tumour cells by resveratrol and EGCG. Gynecologic Oncology, 113(3), 374-378.

Journal - Research Other

Sykes, P., Miller, A., & Peddie, D. (2009). Unsatisfactory cervical cytology screening specimens are associated with missed cervical dysplasia and cancer [Author's reply]. BJOG, 116(6), 867. doi: 10.1111/j.1471-0528.2009.02114.x

Conference Contribution - Published proceedings: Abstract

Dann, J. M., Sykes, P. H., Mason, D. R., & Evans, J. J. (2009). Resveratrol and (-)-epigallocatechin-3-gallate reduce VEGF secretion from endometrial tumour cells. Reproductive Sciences, 16(3, Suppl.), 284, (pp. 151A). doi: 10.1177/193371912009163s167

Kuiper, C., Molenaar, I., Dachs, G., Currie, M., Sykes, P., & Vissers, M. (2009). Low ascorbate levels in endometrial tumours are associated with high HIF-1 activity and a more aggressive phenotype. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]

Dann, J., Evans, J., Sykes, P., Vissers, M., & Mason, D. (2009). Food compounds in the regulation of angiogenic factors in endometrial cancer. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]

Kuiper, C., Molenaar, I., Dachs, G., Currie, M., Sykes, P., & Vissers, M. (2009). Low ascorbate levels in endometrial tumours are associated with high HIF-1 activity and a more aggressive phenotype. Free Radical Biology and Medicine. 47(Suppl. 1), (pp. S172-S173). [Abstract]

2008

Journal - Research Article

Sykes, P. H., Harker, D. Y., Miller, A., Whitehead, M., Neal, H., Wells, J. E., & Peddie, D. (2008). A randomised comparison of SurePath liquid-based cytology and conventional smear cytology in a colposcopy clinic setting. BJOG, 115(11), 1375-1381. doi: 10.1111/j.1471-0528.2008.01865.x

Journal - Research Other

Sykes, P., Sadler, L., & Priest, P. (2008). Screening the hard to reach: Improving morbidity and mortality from cervical cancer in New Zealand [Editorial]. New Zealand Medical Journal, 121(1277). Retrieved from http://journal.nzma.org.nz/journal/121-1277/3135/content.pdf

2007

Journal - Research Article

Jones, R. W., Coughlan, E. P., Reid, J. S., Sykes, P., Watson, P. D., & Cook, C. (2007). Human papilloma virus vaccines and their role in cancer prevention. New Zealand Medical Journal, 120(1266). Retrieved from http://journal.nzma.org.nz/journal/120-1266/2829/content.pdf

Journal - Research Other

North, J., Perez, D., Fentiman, G., Sykes, P., Dempster, A., & Pearse, M. (2007). Primary breast cancer of the vulva: Case report and literature review. Australian & New Zealand Journal of Obstetrics & Gynaecology, 47(1), 77-79. doi: 10.1111/j.1479-828X.2006.00685.x

Conference Contribution - Verbal presentation and other Conference outputs

Sykes, P., Evans, J., Nagasaki, J., Fisher, M., McGraine, Y., & Guilford, P. (2007, May). Understanding angiogenesis in endometrial cancer: A path to new therapies. Verbal presentation at the New Zealand Society for Oncology Conference, Dunedin, New Zealand.

2006

Journal - Research Article

Muys, J. J., Alkaisi, M. M., Melville, D. O. S., Nagase, J., Sykes, P., Parguez, G. M., & Evans, J. J. (2006). Cellular transfer and AFM imaging of cancer cells using Bioimprint. Journal of Nanobiotechnology, 4. Retrieved from http://www.jnanobiotechnology.com/content/4/1/1

Watson, A. J., Smith, B. B., Whitehead, M. R., Sykes, P. H., & Frizelle, F. A. (2006). Malignant progression of anal intra-epithelial neoplasia. ANZ Journal of Surgery, 76(8), 715-717.

Journal - Research Other

Vaughan, M., Sykes, P., Johnson, C., Fitzharris, B., on behalf of the New Zealand Gynaecologic Cancer Group. (2006). Improving outcomes in ovarian cancer [Editorial]. New Zealand Medical Journal, 119(1242). Retrieved from http://journal.nzma.org.nz/journal/119-1242/2171/content.pdf

Conference Contribution - Published proceedings: Abstract

Priest, P., Sadler, L., Sykes, P., Crengle, S., Peters, J., & Marshall, R. (2006). Determinants of ethnic inequalities in cervical cancer survival in New Zealand. Australasian Epidemiologist, 13(3), 69. [Abstract]

Conference Contribution - Verbal presentation and other Conference outputs

Sykes, P. (2006, February). Anal intraepithelial neoplasia. Verbal presentation at the International Society for the Study of Vulvo-vaginal Disease: XVIII World Congree, Queenstown, New Zealand.

Evans, J. J., Muys, J. J., Alkaisi, M. M., Sykes, P. H., Nagase, J., Savigny, P., & McGrath, K. (2006, January). The function of biological cells as revealed by atomic force microscopy. Verbal presentation at the Second BioNanoNetwork (BNN) Meeting, Christchurch, New Zealand.

Sykes, P. (2006, September). New Zealand perspectives on HPV. Verbal presentation at the Vision for Vaccines Symposium, Auckland, New Zealand.

2005

Journal - Research Article

Pather, S., Ford, M., Reid, R., & Sykes, P. (2005). Postpartum curettage: An audit of 200 cases. Australian & New Zealand Journal of Obstetrics & Gynaecology, 45, 368-371.

Sykes, P., Jennings, L., Harker, D., & Beynon, K. (2005). Human papilloma virus is detectable by the Hybrid Capture 2 test in cervical smear samples from women over 40 years of age with high-grade squamous intraepithelial lesions. Australian & New Zealand Journal of Obstetrics & Gynaecology, 45, 457-459.

Sykes, P. H., Reddy, J., & Peddie, D. J. (2005). Does regular cervical screening protect women from microinvasive squamous cell carcinoma of the cervix? A retrospective case-control study. BJOG, 112, 807-809.

Sadler, L., & Sykes, P. (2005). How little is known about cervical cancer in pregnancy? [Editorial]. Annals of Oncology, 16, 341-343.

Sykes, P., Harker, D., & Peddie, D. (2005). Findings and outcome of teenage women referred for colposcopy at Christchurch Women's Hospital, New Zealand. New Zealand Medical Journal, 118(1211). Retrieved from http://journal.nzma.org.nz/journal/118-1211/1350/content.pdf

Conference Contribution - Published proceedings: Abstract

Sykes, P. (2005). Colposcopy and treatment for young women under the age of 20. Proceedings of the Australian Society for Colposcopy and Cervical Pathology 19th Scientific Meeting. [Abstract]

2004

Journal - Research Article

Jones, S., Sykes, P., Pather, S., & Peddie, D. (2004). Is there a role for colposcopy in the follow-up of treated low grade squamous intraepithelial lesions? Australian & New Zealand Journal of Obstetrics & Gynaecology, 44, 574-576.

Losco, G., Sykes, P., Anderson, N., Roberts, H., Fulton, J., & Fraser, H. (2004). Clinical utility of magnetic resonance imaging and the preoperative identification of low risk endometrial cancer. Australian & New Zealand Journal of Obstetrics & Gynaecology, 44(5), 419-422. doi: 10.1111/j.1479-828X.2004.00282.x

Abbas, M. M., Evans, J. J., Sykes, P. H., & Benny, P. S. (2004). Modulation of vascular endothelial growth factor and thymidine phosphorylase in normal human endometrial stromal cells. Fertility & Sterility, 82(Suppl. 3), 1048-1053.

2003

Journal - Research Article

Sykes, P., Allen, D., Cohen, C., Scurry, J., & Yeo, D. (2003). Does the density of lymphatic vascular space invasion affect the prognosis of stage Ib and IIA node negative carcinoma of the cervix? International Journal of Gynecological Cancer, 13, 313-316.

Conference Contribution - Published proceedings: Abstract

Sykes, P. (2003). Does cervical screening prevent microinvasive cancer of the cervix? Proceedings of the Australian Society of Colposcopy and Cervical Pthology XVIIIth Scientific Meeting. [Abstract]

2002

Journal - Research Article

Sykes, P., Nam, S., Wynne, C. J., Anderson, N., North, C. J., Hunter, L., … Fentiman, G. S. (2002). The pre-operative identification of low-risk endometrial cancer: An audit of women treated in the South Island of New Zealand 1998-2000. Australian & New Zealand Journal of Obstetrics & Gynaecology, 42(4), 387-390.

Frizelle, F. A., Beasley, S. W., Roake, J. A., & Sykes, P. (2002). Specialisation within the specialty of general surgery; can the potential advantages be realised? New Zealand Medical Journal, 115, 295-298.

Smith, N., Sykes, P., Frizelle, F. A., & McCormick, P. (2002). High-grade vulval intraepithelial neoplasia (VIN3): A retrospective outcome and relationship to squamous cell carcinoma of the vulva 1989-1999. Australian & New Zealand Journal of Obstetrics & Gynaecology, 42, 67-74.

2001

Journal - Research Article

Pather, S., Sykes, P. H., Davis, R., Reid, R. A., & Skjellerup, N. R. (2001). Thromboprophylaxis following caesarean section; hospital protocols are necessary. New Zealand Medical Journal, 114, 339-340.

Simcock, B., Sykes, P. H., & Laney, M. G. (2001). The impact of the National Cervical Screening Programme on the presentation of cancer of the cervix in Canterbury. New Zealand Medical Journal, 114, 378-380.

1999

Journal - Research Article

Foate, J., Begg, E. J., Anderson, T. J., Bagshaw, P. F., Coulter, G., George, P. M., Macleod, S., … Sykes, P. (1999). The Stent report one year on. New Zealand Medical Journal, 112, 278-279.

1998

Journal - Research Article

Sykes, P., & Mulvaney, P. H. (1998). Mesothelial cell hyperplasia in laparoscopy sites may cause difficulties in the diagnosis, staging, and management of ovarian tumours: a case report. International Journal of Gynecological Cancer, 8, 345-348.

Journal - Research Other

Sykes, P. H., & Mulvany, N. J. (1998). Mesothelial cell hyperplasia in laparoscopy sites may cause difficulties in the diagnosis, staging and management of ovarian tumours: A case report. International Journal of Gynecological Cancer, 8, 345-348.

Black, K., Sykes, P., & Östör, A. G. (1998). Trophoblastic differentiation in an endometrial carcinoma [Case report]. Australian & New Zealand Journal of Obstetrics & Gynaecology, 38(4), 472-473. doi: 10.1111/j.1479-828X.1998.tb03116.x

1997

Journal - Research Article

Sykes, P., Quinn, M. A., & Rome, R. (1997). Ovarian tumours of low malignant potential: A retrospective study of 234 patients. International Journal of Gynecological Cancer, 7, 218-226.

Mulvany, N. J., & Sykes, P. (1997). Desmoplastic melanoma of the vulva. Pathology, 29(2), 241-245. doi: 10.1080/00313029700169974