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Campbell Laboratory

Research interests

I am interested in defining how the gonadotrophin releasing hormone (GnRH) neurons, well established as the ultimate downstream regulators of the central control of reproductive function, are regulated by the multitude of external and internal cues necessary for successful fertility.

At the Centre for Neuroendocrinology I am investigating the synaptic regulation of GnRH neurons, with particular emphasis on the innervation to their lengthy dendrites, through a variety of morphological imaging and transgenic mouse model approaches. In addition to understanding the regulation of normal fertility, I am also interested in addressing the central neuroendocrine abnormalities of polycystic ovarian syndrome (PCOS), the leading cause of infertility in women.

Current and proposed projects:

  • Exploring the neuroendocrine mechanisms of PCOS
  • Mechanisms of pulse generation in the GnRH neuronal network
  • Steroid induced structural plasticity within the GnRH neuronal network

Clinical conditions

  • Infertility
  • Polycystic ovarian syndrome
  • Ciliopathies

Professor Rebecca Campbell's researcher profile

List of publications for Rebecca Campbell (Google Scholar)

Campbell Laboratory staff & students


Maggie Corr Evans_webMaggie Evans, Research Fellow
Email maggie.evans@otago.ac.nz

Kelly Glendining_webKelly Glendining, Research Fellow
Email kelly.glendining@otago.ac.nz

Kyoko Potapov_webKay Potapov, Assistant Research Fellow
Email kyoko.potapov@otago.ac.nz

Mel Prescott_webMel Prescott, Assistant Research Fellow
Role of the brain in PCOS
Email mel.prescott@otago.ac.nz

Celine Camon, PhD student
Email: celine.camon@otago.ac.nz

Emily Lott, B Biomed Sci student

Phoebe Trolove, Pg Dip Sci student

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Publications

Glendining, K. A., & Campbell, R. E. (2023). Recent advances in emerging PCOS therapies. Current Opinion in Pharmacology, 68, 102345. doi: 10.1016/j.coph.2022.102345

Campbell, R. (2022, July). Illuminating the role of the brain in polycystic ovary syndrome. University of Otago, Dunedin, New Zealand. [Inaugural Professorial Lecture].

Emanuel, R. H. K., Roberts, J., Docherty, P. D., Lunt, H., Campbell, R. E., & Möller, K. (2022). A review of the hormones involved in the endocrine dysfunctions of polycystic ovary syndrome and their interactions. Frontiers in Endocrinology, 13, 1017468. doi: 10.3389/fendo.2022.1017468

Evans, M. C., Campbell, R. E., & Anderson, G. M. (2022). Physiological regulation of leptin as an integrative signal of reproductive readiness [Review]. Current Opinion in Pharmacology, 67, 102321. doi: 10.1016/j.coph.2022.102321

Sugrue, V. J., Garratt, M., Campbell, R. E., & Hore, T. A. (2022). Androgens and the epigenetic clock. Proceedings of the joint ESA-SRB-APEG-NZSE Annual Scientific Meeting. 13. Retrieved from https://www.esa-srb-apeg-nzse.org