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Campbell Laboratory

Research interests

I am interested in defining how the gonadotrophin releasing hormone (GnRH) neurons, well established as the ultimate downstream regulators of the central control of reproductive function, are regulated by the multitude of external and internal cues necessary for successful fertility.

At the Centre for Neuroendocrinology I am investigating the synaptic regulation of GnRH neurons, with particular emphasis on the innervation to their lengthy dendrites, through a variety of morphological imaging and transgenic mouse model approaches. In addition to understanding the regulation of normal fertility, I am also interested in addressing the central neuroendocrine abnormalities of polycystic ovarian syndrome (PCOS), the leading cause of infertility in women.

Current and proposed projects:

  • Exploring the neuroendocrine mechanisms of PCOS
  • Mechanisms of pulse generation in the GnRH neuronal network
  • Steroid induced structural plasticity within the GnRH neuronal network

Clinical conditions

  • Infertility
  • Polycystic ovarian syndrome
  • Ciliopathies

Professor Rebecca Campbell's researcher profile

List of publications for Rebecca Campbell (Google Scholar)

Campbell Laboratory staff & students


Maggie Corr Evans_webMaggie Evans, Research Fellow
Email maggie.evans@otago.ac.nz

Kelly Glendining_webKelly Glendining, Research Fellow
Email kelly.glendining@otago.ac.nz

Kyoko Potapov_webKay Potapov, Assistant Research Fellow
Email kyoko.potapov@otago.ac.nz

Mel Prescott_webMel Prescott, Assistant Research Fellow
Role of the brain in PCOS
Email mel.prescott@otago.ac.nz

Amy Ruddenklau_webAmy Ruddenklau, PhD student
Investigating the role of central progesterone signalling in PCOS
Email rudam430@student.otago.ac.nz

Aisha Sati_webAisha Sati, Assistant Research Fellow
Investigating the relationship between androgen excess and microglia in the female brain
Email satai881@student.otago.ac.nz

Celine Camon, PhD student
Email: celine.camon@otago.ac.nz

Dhairya Thakkar, Honours student

Natalya Tongotea, Honours student

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Visit Our people for an alphabetical list of all Centre for Neuroendocrinology staff.

Publications

Campbell, R. E., Sati, A., Coyle, C., Prescott, M., Jasoni, C. L., & Desroziers, E. (2022, August). How androgen excess shapes the polycystic ovary syndrome (PCOS)-like brain. Verbal presentation at the Metabolic & Cardiovascular Disease Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.

Glendining, K. A., Prescott, M., & Campbell, R. E. (2022, August-September). GnRH neuron morphology and kisspeptin-GnRH appositions during postnatal development in a C57BL/6 Mkrn3KO mouse. Poster session presented at the New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Ruddenklau, A., Prescott, M., & Campbell, R. E. (2022, August-September). Chronic inhibition of arcuate nucleus GABA neurons in a preclinical model of polycystic ovary syndrome (PCOS). Poster session presented at the New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Camon, C., Stout, M., Campbell, R., & Pankhurst, M. (2022, August-September). Neuronal estrogen signalling in metabolic health and ageing. Verbal presentation at the New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Sugrue, V. J., Zoller, J. A., Narayan, P., Lu, A. T., Ortega-Recalde, O. J., Grant, M. J., … Bond, D. M., … Campbell, R., Garratt, M., … Hore, T. A. (2022, August-September). Male-specific DNA aging and building the Androgen Clock. Verbal presentation at the New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.