Associate Professor Stephen Bunn
Associate Professor Stephen Bunn's biography
Associate Professor Bunn's researcher profile
List of publications for Stephen Bunn (Google Scholar)
Research interests
Stephen's major research interest at the Centre for Neuroendocrinology was in the neuroendocrinology of stress.
His research focused on two major areas. First, understanding the complex regulation of the adrenal medullary chromaffin cell, specifically how it regulates its secretory output of catecholamines and peptides in response to multiple stress-activated inputs. A lot of the work was directed at understanding how cytokines interact with this stress response.
The second major interest concerned the role of another cytokine, prolactin, on the stress axis. Specifically, Stephen was interested in how stressors alter prolactin secretion from the pituitary and what role this prolactin then plays in stress adaptation under different physiological states.
Publications
Al-Isawi, S. A., Phillipps, H., Yip, S. H., Bunn, S. J., & Grattan, D. R. (2024, August-September). Characterising prolactin receptor expression in the adrenal of dioestrus and lactating mice. Verbal presentation at the 18th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Papaioannou, P., Georgescu, T., Grattan, D. R., Bunn, S., & Yip, S. (2024). Plasticity of the hypothalamic tuberoinfundibular dopaminergic neuronal network in lactating rats. Journal of the Endocrine Society, 8(Suppl. 1), bvae163.1309. doi: 10.1210/jendso/bvae163.1309 Conference Contribution - Published proceedings: Abstract
Szawka, R. E., Bunn, S. J., Le Tissier, P., Yip, S. H., & Grattan, D. R. (2024). Lactation and the control of the prolactin secretion. In P. J. Brunton & D. R. Grattan (Eds.), Neuroendocrine regulation of mammalian pregnancy and lactation. (pp. 181-221). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-51138-7_7 Chapter in Book - Research
Gustafson, P. E., Al-Isawi, S. A., Phillipps, H. R., Crosse, H. W., Grattan, D. R., Bunn, S. J., & Yip, S. H. (2024). The role of prolactin in the suppression of the response to restraint stress in the lactating mouse. Journal of Neuroendocrinology, 36, e13330. doi: 10.1111/jne.13330 Journal - Research Article
Papaioannou, P., Yip, J., Georgescu, T., & Bunn, S. (2022). Lactation-induced desynchronization of the hypothalamic tuberoinfundibular dopaminergic neurons. In L. Wilson, H. Harcombe, P. Jayakaran, L. Burga, J. Antony, K. Morgaine, M. Garelja, A. Middleton, M. Anwar & T. Milne (Eds.), Proceedings of the 263rd Otago Medical School Research Society (OMSRS) Meeting: PhD Student Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839 Conference Contribution - Published proceedings: Abstract
2024
Chapter in Book - Research
Szawka, R. E., Bunn, S. J., Le Tissier, P., Yip, S. H., & Grattan, D. R. (2024). Lactation and the control of the prolactin secretion. In P. J. Brunton & D. R. Grattan (Eds.), Neuroendocrine regulation of mammalian pregnancy and lactation. (pp. 181-221). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-51138-7_7
Journal - Research Article
Gustafson, P. E., Al-Isawi, S. A., Phillipps, H. R., Crosse, H. W., Grattan, D. R., Bunn, S. J., & Yip, S. H. (2024). The role of prolactin in the suppression of the response to restraint stress in the lactating mouse. Journal of Neuroendocrinology, 36, e13330. doi: 10.1111/jne.13330
Conference Contribution - Published proceedings: Abstract
Papaioannou, P., Georgescu, T., Grattan, D. R., Bunn, S., & Yip, S. (2024). Plasticity of the hypothalamic tuberoinfundibular dopaminergic neuronal network in lactating rats. Journal of the Endocrine Society, 8(Suppl. 1), bvae163.1309. doi: 10.1210/jendso/bvae163.1309
Conference Contribution - Verbal presentation and other Conference outputs
Al-Isawi, S. A., Phillipps, H., Yip, S. H., Bunn, S. J., & Grattan, D. R. (2024, August-September). Characterising prolactin receptor expression in the adrenal of dioestrus and lactating mice. Verbal presentation at the 18th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2022
Conference Contribution - Published proceedings: Abstract
Papaioannou, P., Yip, J., Georgescu, T., & Bunn, S. (2022). Lactation-induced desynchronization of the hypothalamic tuberoinfundibular dopaminergic neurons. In L. Wilson, H. Harcombe, P. Jayakaran, L. Burga, J. Antony, K. Morgaine, M. Garelja, A. Middleton, M. Anwar & T. Milne (Eds.), Proceedings of the 263rd Otago Medical School Research Society (OMSRS) Meeting: PhD Student Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839
Conference Contribution - Poster Presentation (not in published proceedings)
Papaioannou, P., Yip, J., Georgescu, T., & Bunn, S. (2022, August-September). Real-time Ca2+ imaging of the tuberoinfundibular dopaminergic neuronal in virgin and lactating rats. Poster session presented at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Cromb, P., Yip, S. H., & Bunn, S. J. (2022, August-September). Detection of enkephalin release from hypothalamic rat brain slices using biosensor cells. Poster session presented at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Alisawi, S. A., & Bunn, S. J. (2022, August-September). Investigating prolactin receptor expression in the mouse adrenal glands. Poster session presented at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2021
Journal - Research Article
Nair, B. B., Khant Aung, Z., Porteous, R., Prescott, M., Glendining, K. A., Jenkins, D. E., Augustine, R. A., Silva, M. S. B., Yip, S. H., Bouwer, G. T., Brown, C. H., Jasoni, C. L., Campbell, R. E., Bunn, S. J., Anderson, G. M., Grattan, D. R., Herbison, A. E., & Iremonger, K. J. (2021). Impact of chronic variable stress on neuroendocrine hypothalamus and pituitary in male and female C57BL/6J mice. Journal of Neuroendocrinology, 33, e12972. doi: 10.1111/jne.12972
Conference Contribution - Published proceedings: Abstract
Aye, W., Georgescu, T., & Bunn, S. (2021). Ca2+-imaging in rat adrenal slices reveal chromaffin cell heterogeneity. New Zealand Medical Journal, 134(1537), (pp. 105-106). Retrieved from https://www.nzma.org.nz/journal
2020
Journal - Research Article
Gustafson, P., Ladyman, S. R., McFadden, S., Larsen, C., Khant Aung, Z., Brown, R. S. E., Bunn, S. J., & Grattan, D. R. (2020). Prolactin receptor-mediated activation of pSTAT5 in the pregnant mouse brain. Journal of Neuroendocrinology, 32, e12901. doi: 10.1111/jne.12901
Yip, S. H., Araujo-Lopes, R., Szawka, R. E., York, J., Hyland, B., Grattan, D. R., & Bunn, S. J. (2020). Morphological plasticity of the tuberoinfundibular dopaminergic neurons in the rat during the estrous cycle and lactation. Journal of Neuroendocrinology, 32(11), e12884. doi: 10.1111/jne.12884
2019
Journal - Research Article
Kirk, S. E., Grattan, D. R., & Bunn, S. J. (2019). The median eminence detects and responds to circulating prolactin in the male mouse. Journal of Neuroendocrinology, 31, e12733. doi: 10.1111/jne.12733
Yip, S. H., Romanò, N., Gustafson, P., Hodson, D. J., Williams, E. J., Kokay, I. C., … Grattan, D. R., & Bunn, S. J. (2019). Elevated prolactin during pregnancy drives a phenotypic switch in mouse hypothalamic dopaminergic neurons. Cell Reports, 26(7), 1787-1799.e5. doi: 10.1016/j.celrep.2019.01.067
Conference Contribution - Poster Presentation (not in published proceedings)
Yip, S. H., Romano, N., Hodson, D. J., Williams, E., Gustafson, P., Kokay, I., … Grattan, D. R., & Bunn, S. J. (2019, September). Elevated prolactin during pregnancy drives a phenotypic switch in mouse hypothalamic dopaminergic neurons. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Aye, W., Georgescu, T., & Bunn, S. J. (2019, August-September). Analysis of Ca2+ imaging in rat adrenal medullary slices. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Yip, S. H., Romano, N., Hodson, D. J., Williams, E., Gustafson, P., Kokay, I., … Grattan, D. R., & Bunn, S. J. (2019, August-September). Switch to motherhood: A glimpse into prolactin secretion. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2018
Journal - Research Article
Yip, S. H., York, J., Hyland, B., Bunn, S. J., & Grattan, D. R. (2018). Incomplete concordance of dopamine transporter Cre (DATIREScre)-mediated recombination and tyrosine hydroxylase immunoreactivity in the mouse forebrain. Journal of Chemical Neuroanatomy, 90, 40-48. doi: 10.1016/j.jchemneu.2017.12.002
Conference Contribution - Published proceedings: Abstract
Bunn, S., Yip, S. H., Grattan, D., Hyland, B., Szawka, R., Araujo-Lopes, R., & York, J. (2018). Morphological plasticity of hypothalamic dopaminergic neurons during estrous cycle and lactation. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 123-124). Retrieved from http://www.icn2018.org/
Conference Contribution - Poster Presentation (not in published proceedings)
Yip, S. H., Georgescu, T., York, J., Kokay, I., Araujo-Lopes, R., Szawka, R. E., Hyland, B. I., Grattan, D. R., & Bunn, S. J. (2018, August). Adaptation of tuberoinfundibular dopaminergic neurons to estrous cycle and lactation. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Gustafson, P. E., Yip, S. H., Bunn, S. J., & Grattan, D. R. (2018, August). Suppression of the response to restraint stress in the lactating mouse. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2017
Journal - Research Article
Gustafson, P., Bunn, S. J., & Grattan, D. R. (2017). The role of prolactin in the suppression of Crh mRNA expression during pregnancy and lactation in the mouse. Journal of Neuroendocrinology, 29(9), e12511. doi: 10.1111/jne.12511
Kirk, S. E., Xie, T. Y., Steyn, F. J., Grattan, D. R., & Bunn, S. J. (2017). Restraint stress increases prolactin-mediated phosphorylation of signal transducer and activator of transcription 5 in the hypothalamus and adrenal cortex in the male mouse. Journal of Neuroendocrinology, 29(6), 1-9. doi: 10.1111/jne.12477
Gustafson, P., Kokay, I., Sapsford, T., Bunn, S., & Grattan, D. (2017). Prolactin regulation of the HPA axis is not mediated by a direct action upon CRH neurons: Evidence from the rat and mouse. Brain Structure & Function, 222(7), 3191-3204. doi: 10.1007/s00429-017-1395-1
Conference Contribution - Published proceedings: Abstract
Nair, B., Khant Aung, Z., Porteous, R., Prescott, M., Ng, J., Yip, S., Augustine, R., Glendining, K., Bouwer, G., Kim, J., Jenkins, D., Silva, M., Brown, C., Campbell, R., Jasoni, C., Bunn, S., Anderson, G., Grattan, D., Herbison, A., & Iremonger, K. (2017). Impact of chronic stress on the neuroendocrine axis in the mouse. In B. Leitch (Ed.), Proceedings of the 35th International Australasian Winter Conference on Brain Research. (pp. 49). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr/index.html
Conference Contribution - Poster Presentation (not in published proceedings)
Yip, S. H., York, J., Araujo-Lopes, R., Szawka, R. E., Hyland, B., Grattan, D. R., & Bunn, S. J. (2017, July). Morphological plasticity of tuberoinfundibular dopaminergic neurons during estrous cycle and lactation. Poster session presented at the Federation of American Societies for Experimental Biology (FASEB) Science Research Conference: The Growth Hormone (GH)/Prolactin (PRL) Family in Biology and Disease, Steamboat Springs, USA.
Gustafson, P. E., Bunn, S. J., & Grattan, D. R. (2017, September). Regulation of the maternal hypothalamic-pituitary-adrenal axis by prolactin. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2016
Journal - Research Article
Jenkins, D. E., Sreenivasan, D., Carman, F., Babru, S., Eiden, L. E., & Bunn, S. J. (2016). Interleukin-6-mediated signaling in adrenal medullary chromaffin cells. Journal of Neurochemistry, 139(6), 1138-1150. doi: 10.1111/jnc.13870
Conference Contribution - Published proceedings: Abstract
Kirk, S., Grattan, D., & Bunn, S. (2016). Prolactin interaction with the median eminence increases phospho-stats and reduces permeability. Proceedings of the Australasian Neuroscience Society (ANS) Annual Scientific Meeting. Retrieved from https://www.ans.org.au
Bunn, S., Kirk, S., & Grattan, D. (2016). Stress-induced prolactin signalling in the male mouse. Proceedings of the Australasian Neuroscience Society (ANS) Annual Scientific Meeting. Retrieved from https://www.ans.org.au
Gustafson, P. E., Bunn, S. J., & Grattan, D. R. (2016). Does prolactin mediate the suppression of the maternal stress response? Endocrine Reviews, 37(2, Suppl.), FRI-506. Retrieved from http://press.endocrine.org/series/endo-meetings
Kirk, S., Grattan, D. R., & Bunn, S. J. (2016). Stress-induced prolactin signalling in the male mouse. Endocrine Reviews, 37(2, Suppl.), FRI-507. Retrieved from http://press.endocrine.org/series/endo-meetings
Conference Contribution - Poster Presentation (not in published proceedings)
Yip, S. H., York, J., Hyland, B., Grattan, D. R., & Bunn, S. J. (2016, August-September). Revealing the morphological plasticity of tuberoinfundibular dopaminergic neurons using an in vivo viral-mediated cell filling technique. Poster session presented at the 17th international Congress of Endocrinology in conjunction with the 15th Annual Meeting of the Chinese Society of Endocrinology, Beijing, China.
York, J., Yip, S. H., Hyland, B., Grattan, D. R., & Bunn, S. J. (2016, August). Morphological characterization of tyrosine hydroxylase immunoreactive neurons in the rat hypothalamus. Poster session presented at the Medical Sciences Congress (MedSci), Nelson, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Bunn, S. J. (2016, August). Neurosecretion: A view from the adrenal chromaffin cell. Verbal presentation at the Medical Sciences Congress (MedSci), Nelson, New Zealand.
Yip, S. H., York, J., Hyland, B., Grattan, D., & Bunn, S. J. (2016, August). Changes in dendritic spine density of tuberoinfundibular dopaminergic neurons associated with estrous cyclicity in the rat. Verbal presentation at the Medical Sciences Congress (MedSci), Nelson, New Zealand.
2015
Conference Contribution - Published proceedings: Abstract
Bunn, S., Williams, E., Yip, J., & Grattan, D. (2015). Prolactin-dependent regulation of enkephalin expression in the tuberoinfundibular dopaminergic neurons of the lactating mouse. Journal of Neurochemistry, 134(Suppl. 1), (pp. 228). doi: 10.1111/jnc.13188
Conference Contribution - Poster Presentation (not in published proceedings)
Yip, S. H., Williams, E., Grattan, D., & Bunn, S. (2015, September). Prolactin receptor-mediated enkephalin expression in TIDA neurons of late pregnant and lactating mice. Poster session presented at the 3rd Joint Meeting of the British and French Societies for Neuroendocrinology (BSN-SNE), Lille, France.
Tranter, D. E., & Bunn, S. J. (2015, August-September). The murine adrenal gland is responsive to immune signals in vivo. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Williams, E. J., Yip, S. H., Grattan, D. R., & Bunn, S. (2015, August-September). Prolactin signalling in the arcuate nucleus of pregnant and lactating mice. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Kirk, S., Grattan, D., & Bunn, S. (2015, August-September). Decreased permeability of the median eminence in response to acute prolactin elevation. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2014
Conference Contribution - Published proceedings: Abstract
Pyun, J., Williams, E., Matsas, M., Potapov, D., Abraham, I., & Bunn, S. (2014). Estrogenic modulation of TRKA signalling in PC12 cells. Proceedings of the Australasian Neuroscience Society 34th Annual Meeting. Retrieved from http://www.ans.org.au/
Tranter, D. E., & Bunn, S. J. (2014). The murine adrenal gland is IL-6 responsive in vivo. Proceedings of the Medical Sciences Congress (MedSci). (pp. 38). Retrieved from http://www.physoc.org.nz/meetings/archive/medsci-2014-abstracts
Gustafson, P., Bunn, S., & Grattan, D. (2014). Suppression of basal HPA axis activity in the late pregnant and lactating mouse. Proceedings of the Medical Sciences Congress (MedSci). (pp. 18). Retrieved from http://www.physoc.org.nz/meetings/archive/medsci-2014-abstracts
Kirk, S. E., Grattan, D. R., & Bunn, S. J. (2014). Prolactin signalling in the median eminence and mediobasal hypothalamus of the male mouse. Proceedings of the Medical Sciences Congress (MedSci). (pp. 17). Retrieved from http://www.physoc.org.nz/meetings/archive/medsci-2014-abstracts
2013
Journal - Research Article
Samal, B., Ait-Ali, D., Bunn, S., Mustafa, T., & Eiden, L. E. (2013). Discrete signal transduction pathway utilization by a neuropeptide (PACAP) and a cytokine (TNF-alpha) first messenger in chromaffin cells, inferred from coupled transcriptome-promoter analysis of regulated gene cohorts. Peptides, 45, 48-60. doi: 10.1016/j.peptides.2013.03.020
Romanò, N., Yip, S. H., Hodson, D. J., Guillou, A., Parnaudeau, S., Kirk, S., … Bunn, S. J., Grattan, D. R., … Martin, A. O. (2013). Plasticity of hypothalamic dopamine neurons during lactation results in dissociation of electrical activity and release. Journal of Neuroscience, 33(10), 4424-4433. doi: 10.1523/jneurosci.4415-12.2013
Conference Contribution - Published proceedings: Abstract
Kirk, S., Grattan, D. R., & Bunn, S. J. (2013). Lactation-induced changes in phospho-STAT5 and phospho-ERK signalling in tuberoinfundibular dopaminergic neurons. Proceedings of the Australasian Neuroscience Society (ANS) Annual Meeting. (pp. 35). Retrieved from http://www.ans.org.au/
Bunn, S. J., Yip, S. H., Kirk, S. E., Gustafson, P. E., & Grattan, D. R. (2013). Modification of prolactin signaling in the arcuate nucleus of the mouse during lactation. Proceedings of the Society for Neuroscience 43rd Annual Meeting. SfN. Retrieved from http://www.sfn.org/annual-meeting/neuroscience-2013/abstracts-and-sessions
Conference Contribution - Verbal presentation and other Conference outputs
Williams, E., Pyun, J., Abraham, I., & Bunn, S. (2013, August). Do estrogens affect NGF-mediated differentiation of PC12 cells? Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Tranter, D. E., & Bunn, S. J. (2013, August). Does interleukin-6 alter chromaffin cell function in the mouse adrenal medulla? Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Kirk, S., Grattan, D., & Bunn, S. (2013, August). Prolactin signalling in the mouse median eminence. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Gustafson, P., Bunn, S., & Grattan, D. (2013, August). Regulation of the stress response during pregnancy and lactation. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Bunn, S. (2013, August). Is the adrenal medulla responsive to cytokines? Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2012
Journal - Research Article
Bunn, S. J., Ait-Ali, D., & Eiden, L. E. (2012). Immune-neuroendocrine integration at the adrenal gland: Cytokine control of the adrenomedullary transcriptome. Journal of Molecular Neuroscience, 48(2), 413-419. doi: 10.1007/s12031-012-9745-1
Yip, S. H., Eguchi, R., Grattan, D. R., & Bunn, S. J. (2012). Prolactin signalling in the mouse hypothalamus is primarily mediated by signal transducer and activator of transcription factor 5b but not 5a. Journal of Neuroendocrinology, 24(12), 1484-1491. doi: 10.1111/j.1365-2826.2012.02357.x
Conference Contribution - Published proceedings: Abstract
Tranter, D. E., Douglas, S. A., & Bunn, S. J. (2012). Interleukin-6 regulation of gene expression in bovine adrenal medullary chromaffin cells. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 147). Retrieved from http://www.ans.org.au/ans-annual-conference/
Yip, S. H., Eguchi, R., Grattan, D. R., & Bunn, S. J. (2012). Prolactin signals via the Stat5B but not the Stat5A pathway in the mouse hypothalamus. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 145). Retrieved from http://www.ans.org.au/ans-annual-conference/
Gustafson, P., Bunn, S., & Grattan, D. (2012). Characterisation of a tamoxifen-inducible STAT5 knockout mouse. New Zealand Medical Journal, 125(1367). Retrieved from http://www.nzma.org.nz/journal
Quennell, J. H., Khant Aung, Z., Augustine, R. A., Rizwan, M. Z., Inglis, M. A., Bunn, S. J., & Anderson, G. M. (2012). Evidence for direct estrogenic upregulation of suppressor of cytokine signaling-3 in the mouse brain. Proceedings of the Society for Neuroscience 42nd Annual Meeting. SfN. Retrieved from http://www.sfn.org/index.aspx?pagename=abstracts_am2012
Bunn, S. J., Yip, S. H., Eguchi, R., & Grattan, D. (2012). Prolactin signaling in the mouse hypothalamus. Proceedings of the Society for Neuroscience 42nd Annual Meeting. SfN. Retrieved from http://www.sfn.org/index.aspx?pagename=abstracts_am2012
Tranter, D. E., Kaur, J., Douglas, S. A., & Bunn, S. J. (2012). Immune activation of adrenal medullary chromaffin cells. Proceedings of the Medical Sciences Congress (MedSci). (pp. 62-63). Retrieved from http://www.medscinz.co.nz/QRW2012%20MedSci%20Abstracts.pdf
Pyun, J., Matsas, M., Potapov, D., Abraham, I. M., & Bunn, S. J. (2012). Estrogenic interaction with TRK-A receptors on PC12 cells. Proceedings of the Medical Sciences Congress (MedSci). (pp. 59). Retrieved from http://www.medscinz.co.nz/QRW2012%20MedSci%20Abstracts.pdf
Kirk, S., Gustafson, P., Grattan, D., & Bunn, S. (2012). Changes in hypothalamic signalling in tuberoinfundibular dopaminergic neurons during lactation. Proceedings of the Medical Sciences Congress (MedSci). (pp. 55). Retrieved from http://www.medscinz.co.nz/QRW2012%20MedSci%20Abstracts.pdf
2011
Journal - Research Article
Knowles, P. J., Douglas, S. A., & Bunn, S. J. (2011). Nicotinic stimulation of catecholamine synthesis and tyrosine hydroxylase phosphorylation in cervine adrenal medullary chromaffin cells. Journal of Neuroendocrinology, 23(3), 224-231. doi: 10.1111/j.1365-2826.2010.02100.x
Conference Contribution - Published proceedings: Abstract
Sreenivasan, D., & Bunn, S. J. (2011). Interleukin-6 activation of MAP-kinase pathways in adrenal medullary chromaffin cells. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 152). Retrieved from http://www.ans.org.au/uploads/documents/2011%20Docs/conference%20abstracts/ANS%202011%20Poster%20Abstracts.pdf
Yip, S. H., Grattan, D. R., & Bunn, S. J. (2011). Enkephalin expression in the tuberoinfundibular dopaminergic neurons of the lactating mouse is prolactin-dependent. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 65). Retrieved from http://www.ans.org.au/uploads/documents/2011%20Docs/conference%20abstracts/ANS%202011%20Oral%20Abstracts.pdf
Romano, N., Yip, S. H., Hodson, D. J., Guillou, A., Parnaudeau, S., Tronche, F., … Bunn, S. J., Grattan, D. R., … Martin, A. O. (2011). Phenotypic and functional plasticity in hypothalamic dopamine neurons associated with robust electrophysiological properties. Proceedings of the Society for Neuroscience 41st Annual Meeting. SfN. Retrieved from http://www.sfn.org/am2011/index.aspx?pagename=abstracts_main
Tranter, D., Douglas, S. A., & Bunn, S. J. (2011). Interleukin-6 regulation of adrenal medullary chromaffin cells. In B. Leitch (Ed.), Proceedings of the 29th International Australasian Winter Conference on Brain Research. 29, 5.24. AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/abstracts/abstracts2011.html
Khant Aung, Z., Augustine, R., Bunn, S. J., & Anderson, G. (2011). Estradiol modulates cytokine signaling pathways within the brain. In B. Leitch (Ed.), Proceedings of the 29th International Australasian Winter Conference on Brain Research. 29, 5.23. AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/abstracts/abstracts2011.html
Yip, S. H., Kirk, S., Grattan, D. R., & Bunn, S. J. (2011). Prolactin signaling in the tuberoinfundibular dopaminergic neurons of the lactating mouse. In B. Leitch (Ed.), Proceedings of the 29th International Australasian Winter Conference on Brain Research. 29, 5.22. AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/abstracts/abstracts2011.html
Matsas, M., Potapov, D., Abraham, I., & Bunn, S. J. (2011). Estrogen modulation of TrkA receptor signaling in PC12 cells. In B. Leitch (Ed.), Proceedings of the 29th International Australasian Winter Conference on Brain Research. 29, 5.12. AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/abstracts/abstracts2011.html
Yip, S. H., Eguchi, R., Bunn, S. J., & Grattan, D. R. (2011). Prolaction activates Stat5b but not Stat5a signaling in the mouse hypothalamus. In B. Leitch (Ed.), Proceedings of the 29th International Australasian Winter Conference on Brain Research. 29, 4.4. AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/abstracts/abstracts2011.html
2010
Journal - Research Article
Douglas, S. A., Sreenivasan, D., Carman, F. H., & Bunn, S. J. (2010). Cytokine interactions with adrenal medullary chromaffin cells. Cellular & Molecular Neurobiology, 30(8), 1467-1475. doi: 10.1007/s10571-010-9593-x
Conference Contribution - Published proceedings: Abstract
Sreenivasan, D., & Bunn, S. (2010). Interleukin-6 interacts with bovine adrenal medullary chromaffin cells. New Zealand Medical Journal, 123(1327). Retrieved from http://journal.nzma.org.nz/journal/123-1327/4493/content.pdf
Conference Contribution - Verbal presentation and other Conference outputs
Yip, S. H., Grattan, D. R., & Bunn, S. J. (2010, November-December). Prolactin-dependent enkephalin expression in TIDA neurons of lactating mice. Verbal presentation at the Medical Sciences Congress: A New Decade of Discovery (MedSciNZ), Queenstown, New Zealand.
2009
Journal - Research Article
Douglas, S. A., & Bunn, S. J. (2009). Interferon-α signalling in bovine adrenal chromaffin cells: Involvement of signal-transducer and activator of transcription 1 and 2, extracellular signal-regulated protein kinases 1/2 and serine 31 phosphorylation of tyrosine hydroxylase. Journal of Neuroendocrinology, 21(3), 200-207. doi: 10.1111/j.1365-2826.2009.01821.x
Conference Contribution - Published proceedings: Abstract
Bunn, S. J., Carman, F. H., & Douglas, S. A. (2009). Interleukin-6 mediated signaling in bovine adrenal medullary chromaffin cells. Proceedings of the Society for Neuroscience 39th Annual Meeting. SfN. Retrieved from http://www.abstractsonline.com/plan/AdvancedSearch.aspx
2008
Journal - Research Article
Grattan, D. R., Steyn, F. J., Kokay, I. C., Anderson, G. M., & Bunn, S. J. (2008). Pregnancy-induced adaptation in the neuroendocrine control of prolactin secretion. Journal of Neuroendocrinology, 20(4), 497-507. doi: 10.1111/j.1365-2826.2008.01661.x
Douglas, S. A., Stevenson, K. E., Knowles, P. J., & Bunn, S. J. (2008). Characterization of catecholamine release from deer adrenal medullary chromaffin cells. Neuroscience Letters, 445(1), 126-129. doi: 10.1016/j.neulet.2008.08.060
Conference Contribution - Verbal presentation and other Conference outputs
Carman, F., Douglas, S., & Bunn, S. (2008, November). Interleukin-6 activates STAT3 and ERK1/2 in adrenal medullary chromaffin. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.
Yip, S. H., Grattan, D. R., & Bunn, S. J. (2008, November). Prolactin enhances enkephalin expression in mediobasal hypothalamic cell cultures. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.
Shadanbaz, S., Douglas, S., & Bunn, S. (2008, November). Estrogen receptor expression and activation in bovine adrenal chromaffin cells. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.
2006
Journal - Research Article
O'Sullivan, K. M., & Bunn, S. J. (2006). Phospholipase C isozymes are differentially distributed in the rat adrenal medulla. Neuroscience Letters, 396, 212-216. doi: 10.1016/j.neulet.2005.11.033
Anderson, G. M., Beijer, P., Bang, A. S., Fenwick, M. A., Bunn, S. J., & Grattan, D. R. (2006). Suppression of prolactin-induced signal transducer and activator of transcription 5b signaling and induction of suppressors of cytokine signaling messenger ribonucleic acid in the hypothalamic arcuate nucleus of the rat during late pregnancy and lactation. Endocrinology, 147(10), 4996-5005.
Conference Contribution - Published proceedings: Abstract
Augustine, R., Bunn, S., & Grattan, D. (2006). Quantitation of leptin receptor mRNA in the hypothalamus of the extended-pseudopregnant rat. Proceedings of the New Zealand Society of Endocrinology Annual Meeting. NZSE. Retrieved from http://nzse.rsnz.org/NZSE%20Abstracts%202006.pdf
Bunn, S., Douglas, S., Matheos, K., & Milne, B. (2006). Cytokine-mediated signalling in adrenal medullary chromaffin cells. Proceedings of the New Zealand Society of Endocrinology Annual Meeting. NZSE. Retrieved from http://nzse.rsnz.org/NZSE%20Abstracts%202006.pdf
2005
Journal - Research Article
Ma, F. Y., Anderson, G. M., Gunn, T. D., Goffin, V., Grattan, D. R., & Bunn, S. J. (2005). Prolactin specifically activates signal transducer and activator of transcription 5b in neuroendocrine dopaminergic neurons. Endocrinology, 146(12), 5112-5119.
Ma, F. Y., Grattan, D. R., Goffin, V., & Bunn, S. J. (2005). Prolacting-regulated tyrosine hydroxylase activity and messenger ribonucleic acid expression in mediobasal hypothalamic cultures: The differential role of specific protein kinases. Endocrinology, 146(1), 93-102.
2004
Journal - Research Article
Ma, F. Y., Grattan, D. R., Bobrovskaya, L., Dunkley, P. R., & Bunn, S. J. (2004). Angiotensin II regulates tyrosine hydroxylase activity and mRNA expression in rat mediobasal hypothalamic cultures: The role of specific protein kinases. Journal of Neurochemistry.
Conference Contribution - Published proceedings: Abstract
Augustine, R. A., Bunn, S. J., & Grattan, D. R. (2004). Hypothalamic response to leptin is not suppressed in hyperphagic pseudopregnant rats. Proceedings of the Society for Neuroscience Abstracts. (893.20). Retrieved from http://sfn.scholarone.com/itin2004/index.html
Augustine, R. A., Bunn, S. J., & Grattan, D. R. (2004). Hyperphagia in the pseudopregnant rat is associated with normal hypothalamic response to leptin. Proceedings of the Australasian Winter Conference on Brain Research. (7.2), (pp. 40). [Abstract]
Augustine, R., Bunn, S., & Grattan, D. (2004). Differing hypothalamic responses in pseudopregnant and pregnant rats after central leptin administration. New Zealand Medical Journal, 117(1202). Retrieved from http://journal.nzma.org.nz/journal/117-1202/1086/content.pdf
Bunn, S. J., Ma, F. Y., & Grattan, D. R. (2004). Prolactin stimulates STAT5b phosphorylation and nuclear translocation in cultured fetal rat dopaminergic hypothalamic neurons. Journal of Neurochemistry, 88(Suppl. 1), (pp. 82). doi: 10.1046/j.1474-1644.2003.2314p33_01.x
Bunn, S. J., Knowles, P., & Douglas, S. (2004). Nicotinic stimulation of tyrosine hydroxylase activity in deer adrenal medullary chromaffin cells. Proceedings of the Australian Neuroscience Society. 15, (pp. 118). [Abstract]
2003
Journal - Research Article
Tompkins, M., Gai, W. P., Douglas, S., & Bunn, S. J. (2003). α-Synuclein expression localizes to the Golgi apparatus in bovine adrenal medullary chromaffin cells. Brain Research, 984, 233-236.
O'Connell, G., Douglas, S., & Bunn, S. J. (2003). The involvement of specific phospholipase C isozymes in catecholamine release from digitonin permeabilized bovine adrenal medullary chromaffin cells. Neuroscience Letters, 342, 1-4.
Conference Contribution - Published proceedings: Abstract
Bunn, S. J., Ma, F. Y., Bobrovskaya, L., Dunkley, P. R., & Grattan, D. R. (2003). Angiotensin II activates tyrosine hydroxylase activity and gene expression in cultured hypothalamic dopaminergic neurons. Proceedings of the 21st International Australasian Winter Conference on Brain Research. 21. Queenstown: AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts2003.htm#Bunn
Grattan, D. R., Liu, L., Augustine, R. A., Davey, H. W., & Bunn, S. J. (2003). Sex differences in hypothalamic dopamine neurons are independent of prolactin signalling through STAT5b. Trabajos del Instituto Cajal. Tomo LXXIX, (pp. 208-209). [Abstract]
Ma, F. Y., Grattan, D. R., & Bunn, S. J. (2003). Prolactin regulation of tyrosine hydroxylase activity and expression in cultured hypothalamic dopaminergic neurons. Proceedings of the Endocrine Society of Australia. 46, (pp. 185). [Abstract]
Ma, F. Y., & Bunn, S. J. (2003). The regulation of tyrosine hydroxylase activity and expression in cultured rat hypothalamic neurons. In P. Marbin (Ed.), Proceedings of the Australian Neuroscience Society Twenty-Third Annual Meeting. 14, (pp. 191). Adelaide, Australia: ANS. [Abstract]
Gunn, T. D., Ma, F. Y., Grattan, D. R., & Bunn, S. J. (2003). Prolactin activation of the STAT-signalling pathway in cultured hypothalamic dopaminergic neurons. Proceedings of the 21st International Australasian Winter Conference on Brain Research. Queenstown: AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts2003.htm#Gunn
2002
Conference Contribution - Published proceedings: Abstract
Hurst, P. R., Garry, P. G., & Bunn, S. J. (2002). Incorporation of BrdU into the ovarian surface epithelium in mature mouse ovary slices maintained in culture. Proceedings of the 33rd Annual Conference of the Society of Reproductive Biology. Reproduction, Fertility and Development. 14, (pp. 64). Victoria, Australia: CSIRO Publishing. [Abstract]
Bunn, S. J., & O'Sullivan, K. (2002). Are phospholipase C isozymes differentially distributed in the rat adrenal medulla? Proceedings of the New Zealand Society of Endrocrinology. (pp. 32). New Zealand: New Zealand Society of Endocrinology. [Abstract]
Ma, F., Grattan, D. R., & Bunn, S. J. (2002). Angiotensin II increases tyrosine hydroxylase activity in hypothalamic tuberoinfundibular dopaminergic neurons. Proceedings of the 45th Annual Scientific Meeting. 45, (pp. 160). Endocrine Society of Australia. [Abstract]
Liu, L., Davey, H. W., Augustine, R. A., Bunn, S. J., & Grattan, D. R. (2002). Sex differences in the neuroendocrine regulation of prolactin secretion are not mediated by the transcriptions factor STAT5b. Proceedings of the 45th Annual Scientific Meeting. 45, (pp. 164). Endocrine Society of Australia. [Abstract]
O'Sullivan, K., & Bunn, S. J. (2002). The distribution of phospholipase C isozymes in the rat adrenal medulla: An immunocytochemical study. In P. Pilowsky (Ed.), Proceedings of the Australian Neuroscience Society. 13, (pp. 107). Australia: Australian Neuroscience Society. [Abstract]
2001
Journal - Research Article
Grattan, D. R., Pi, X. J., Andrews, Z. B., Augustine, R. A., Kokay, I. C., Summerfield, M. R., Todd, B., & Bunn, S. J. (2001). Prolactin receptors in the brain during pregnancy and lactation: Implications for behaviour. Hormones & Behavior, 40, 115-124.
Grattan, D. R., Xu, J., McLachlan, M. J., Kokay, I. C., Bunn, S. J., Hovey, R. C., & Davey, H. W. (2001). Feedback regulation of PRL secretion is mediated by the transcription factor, signal transducer, and activator of transcription 5b. Endocrinology, 142(9), 3935-3940.
Conference Contribution - Published proceedings: Abstract
Bunn, S. J., Douglas, S., & Stevenson, K. (2001). Ca2+-channels and catecholamine secretion from deer adrenal chromaffin cells. Proceedings of the Endocrine Society of Australia 2000. New Zealand: New Zealand Endocrinology Society. [Abstract]
Tompkins, M., & Bunn, S. J. (2001). Distinct labelling of subcellular compartments in bovine adrenal medullary cultures using different a-synuclein antibodies. Proceedings of the International Australasian Winter Conference on Brain Research. 19. Retrieved from http://www.awcbr.org/
O'Connell, G., Douglas, S., & Bunn, S. J. (2001). The role of phospholipase C isozymes in Ca2+ stimulated exocytosis from permeabilized bovine adrenal medullary chromaffin cells. Australian Neuroscience Society and the Asian Pacific Society for Neurochemistry. (pp. 195). Brisbane, Australia: Australian Neuroscience Society. [Abstract]
O'Connell, G., Douglas, S., & Bunn, S. J. (2001). Inhibition of phospholipase C-yl reduces Ca 2+-stimulated exocytosis from permeabilized adrenal medullary chromaffin cells. International Society for Neurochemistry and the American Society of Neurochemistry. (1), Supplement, (pp. 201). Journal of Neurochemistry. [Abstract]
O'Connell, G., Douglas, S., & Bunn, S. J. (2001). Phospholipase C isozymes in Ca2+-stimulated exocytosis from permeablilized bovine adrenal medullary chromaffin cells. 19th International Australasian Winter Conference on Brain Research. Retrieved from http://www.awcbr.org
Ma, F., Grattan, D. R., & Bunn, S. J. (2001). The characterisation of tyrosine hydroxylase activity in tuberoinfundibular dopaminergic neurons in vitro. 19th International Australasian Winter Conference on Brain Research. http://www. awcbr.org. Retrieved from http://www.awcbr.org
2000
Journal - Research Article
Roberts-Thomson, E., Palmer, S. M., Powis, D. A., & Bunn, S. J. (2000). Histamine-stimulated phospholipase C activity in bovine adrenal medullary chromaffin cells: The effect of chloride-channel antagonists and low extracellular chloride concentrations. Neuroscience Letters, 278, 93-96.
Roberts-Thomson, E., Saunders, H. I., Palmer, S. M., Powis, D. A., Dunkley, P. R., & Bunn, S. J. (2000). Ca2+ influx stimulated phospholipase C activity in bovine adrenal chromaffin cells: Responses to K+ depolarization and histamine. European Journal of Pharmacology, 398, 199-207.
Conference Contribution - Published proceedings: Abstract
Bunn, S. J., Douglas, S., & Stevenson, K. (2000). Catecholamine secretion from deer adrenal medullary chromaffin cells. Australian Soc. Neuroscience. 11, (pp. P2-206). [Abstract]
Grattan, D. R., Xu, J., McLachlan, M. J., Kokay, I. C., Bunn, S. J., & Davey, H. W. (2000). Impaired feedback regulation of prolactin secretion in stat5b-deficient mice. Proceedings of the 11th International Congress of Endocrinology. (pp. 1429). [Abstract]
1999
Journal - Research Article
Cheah, T. B., Bobrovskaya, L., Goncalves, C.-A., Hall, A., Elliot, R., Lengyel, I., Bunn, S. J., … Dunkley, P. R. (1999). Simultaneous measurement of tyrosin hydroxylase activity and phosphorylation in bovine adrenal chromaffin cells. Journal of Neuroscience Methods, 87, 167-174.
Conference Contribution - Published proceedings: Abstract
Roberts-Thomson, E., Saunders, H. I., Dunkley, P. R., & Bunn, S. J. (1999). Phospholipase C activity in bovine chromaffin cells in response to insulin and insulin-like growth factors. 10th International Symposium on Chromaffin Cell Biology. (pp. 175). [Abstract]
Roberts-Thomson, E., Saunders, H. I., Dunkley, P. R., & Bunn, S. J. (1999). The effect of insulin on phospholipase C activity in bovine adrenal medullary chromaffin cells. International Society for Neurochemistry. [Abstract]
1998
Journal - Research Article
Bobrovskaya, L., Cheah, T. B., Bunn, S. J., & Dunkley, P. R. (1998). Tyrosine hydroxylase in bovine adrenal chromaffin cells: Angiotensin II-stimulated activity and phosphorylation of Ser19, Ser31, and Ser40. Journal of Neurochemistry, 70, 2565-2573.
Zerbes, M., Bunn, S. J., & Powis, D. A. (1998). Histamine causes Ca2+ entry via both a store-operated and a store-independent pathway in bovine adrenal chromaffin cells. Cell Calcium, 23(6), 379-386.
Conference Contribution - Published proceedings: Abstract
Palmer, S. M., Powis, D. A., & Bunn, S. J. (1998). The influence of Cl-fluxes on phospholipase C activity in bovine adrenal chromaffin cells. Proceedings of the Australian Neuroscience Society. 9. [Abstract]
Saunders, H. I., & Bunn, S. J. (1998). The distribution of phospholipase C isozymes in bovine adrenal chromaffin cells. Proceedings of the Australian Neuroscience Society. 9, (pp. 106). [Abstract]
Roberts-Thomson, E., & Bunn, S. J. (1998). The regulation of phospholipase Cγ1 in bovine adrenal chromaffin cells. Proceedings of the Australian Neuroscience Society. 9, (pp. 105). [Abstract]
Bunn, S. J. (1998). Phospholipase C signalling in the adrenal chromaffin cell. The 4th meeting of the Asian-Pacific Society for Neurochemistry. 70(2), (pp. S6D). Journal of Neurochemistry. [Abstract]
1997
Journal - Research Article
Bunn, S. J., & Dunkley, P. R. (1997). Histamine-stimulated phospholipase C signalling in the adrenal medullary chromaffin cell: Effect on inositol phospholipid metabolism and tyrosine hydroxylase phosphorylation. Clinical & Experimental Pharmacology & Physiology, 24, 624-631.
Conference Contribution - Published proceedings: Abstract
Bunn, S. J., & Roberts-Thomson, E. (1997). Histaminergic-mediated phospholipase C activity in bovine adrenal chromaffin cells requires Ca2+-influx. FEBS Special Meeting 'Cell Signalling Mechanisms'. Amsterdam. [Abstract]
Goncalves, C.-A., Hall, A., Sim, A. T. R., Bunn, S. J., Marley, P. D., Cheah, T. B., & Dunkley, P. R. (1997). Tyrosine hydroxylase phosphorylation in digitonin permeabilised bovine adrenal chromaffin cells. International Society Neurochemistry. Boston, USA. [Abstract]
Zerbes, M., Bunn, S. J., & Prowis, D. A. (1997). Pathways of histamine-induced calcium entry in bovine chromaffin cells. Proceedings of Australian Neuroscience Society. 8. [Abstract]
Cheah, T. B., Bobrovskaya, L., Dunkley, P. R., & Bunn, S. J. (1997). Activation of tyrosine hydroxylase by angiotensin II in bovine adrenal chromaffin cells. Proceedings of the Australian Neuroscience Society. 8, (pp. 4-36). [Abstract]
Bobrovskaya, L., Buckenham, A., Bunn, S. J., Cheah, T. B., & Dunkley, P. R. (1997). Effects of protein kinase inhibitors on tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells. Proceedings of the Australian Neuroscience Society. 8, (pp. 4-35). [Abstract]
1995
Edited Book - Research
Powis, D. A., & Bunn, S. J. (Eds.). (1995). Neurotransmitter Release and its Modulation. Cambridge: Cambridge University Press, 10p.