Professor Natalie Hughes

Contact Details
- Phone
- +64 3 479 5919
- natalie.hughes@otago.ac.nz
University Links
- Position
- Professor, Deputy Dean and Associate Dean (Undergraduate Programmes)
- Qualifications
- PhD BSc(Stats) BPharm
- Research summary
- Clinical pharmacy; drug delivery
- Teaching
- Biopharmaceutics, drug delivery and clinical pharmaceutics to undergraduate and postgraduate students.
Research
Drug delivery in clinical pharmacy. This involves research spanning basic research of drug delivery systems, and their optimal use in patients.
Protein drug physical stability and analytical methods to study interactions between protein drugs and formulation excipients.
Additional details
Referee of articles in the pharmaceutical sciences.
Publications
Woods, S. J., Hughes-Medlicott, N. J., & McDowell, A. (2023). Pharmacokinetics in penguins compared to other avian species: A review of enrofloxacin and voriconazole. Molecular Pharmaceutics. Advance online publication. doi: 10.1021/acs.molpharmaceut.3c00520
Ameratunga, R., Mears, E., Leung, E., Snell, R., Woon, S.-T., Kelton, W., Medlicott, N., … Steele, R., Rolleston, W., … Lehnert, K. (2023). Soluble wild-type ACE2 molecules inhibit newer SARS-CoV-2 variants and are a potential antiviral strategy to mitigate disease severity in COVID-19. Clinical & Experimental Immunology, uxad096. Advance online publication. doi: 10.1093/cei/uxad096
Broughton, L. C., Hughes-Medlicott, N., Zeng, J., & Smith, A. (2023). Perinatal psychotropic dispensing: A descriptive population-based study in New Zealand. Asia-Pacific Psychiatry. Advance online publication. doi: 10.1111/appy.12539
Besley, N., Browne, P., Park, M., Pesheva, P., Wong, K., Medlicott, N. J., & McDowell, A. (2023). Pharmacists in zoos? A qualitative study investigating the potential for pharmacist involvement in wildlife healthcare in Aotearoa New Zealand. Journal of the American Pharmacists Association. Advance online publication. doi: 10.1016/j.japh.2023.01.008
Kremer, L. J., Medlicott, N., Sime, M. J., Broadbent, R., Edmonds, L., Berry, M. J., Austin, N. C., … Reith, D. M. (2023). Low dose or very low dose phenylephrine and cyclopentolate microdrops for retinopathy of prematurity eye examinations (The Little Eye Drop Study): A randomised controlled non-inferiority trial. Archives of Disease in Childhood: Fetal & Neonatal Edition, 108, F380-F386. doi: 10.1136/archdischild-2022-324929
Hanning, S. M., Medlicott, N. J., & Oliphant, E. A. (2019). Clinical pharmacy considerations in special population: Pediatrics. In Z. U.-D. Babar (Ed.), Encyclopedia of pharmacy practice and clinical pharmacy (Vol. 3: Part A). (1st ed.) (pp. 815-830). Amsterdam, The Netherlands: Elsevier. doi: 10.1016/B978-0-12-812735-3.00574-4
Chapter in Book - Research
Braund, R., & Medlicott, N. J. (2013). Biomaterials as platforms for topical administration of therapeutic agents in cutaneous wound healing. In S. Dumitriu & V. Popa (Eds.), Polymeric biomaterials: Structure and function. (pp. 837-850). Boca Raton, FL: CRC Press.
Chapter in Book - Research
McDowell, A., & Medlicott, N. J. (2012). Anatomy and physiology of the injection site: Implications for extended release parenteral systems. In J. C. Wright & D. J. Burgess (Eds.), Long acting injections and implants. (pp. 57-71). New York: Springer. doi: 10.1007/978-1-4614-0554-2_4
Chapter in Book - Research
Ameratunga, R., Mears, E., Leung, E., Snell, R., Woon, S.-T., Kelton, W., Medlicott, N., … Steele, R., Rolleston, W., … Lehnert, K. (2023). Soluble wild-type ACE2 molecules inhibit newer SARS-CoV-2 variants and are a potential antiviral strategy to mitigate disease severity in COVID-19. Clinical & Experimental Immunology, uxad096. Advance online publication. doi: 10.1093/cei/uxad096
Journal - Research Article
Besley, N., Browne, P., Park, M., Pesheva, P., Wong, K., Medlicott, N. J., & McDowell, A. (2023). Pharmacists in zoos? A qualitative study investigating the potential for pharmacist involvement in wildlife healthcare in Aotearoa New Zealand. Journal of the American Pharmacists Association. Advance online publication. doi: 10.1016/j.japh.2023.01.008
Journal - Research Article
Broughton, L. C., Hughes-Medlicott, N., Zeng, J., & Smith, A. (2023). Perinatal psychotropic dispensing: A descriptive population-based study in New Zealand. Asia-Pacific Psychiatry. Advance online publication. doi: 10.1111/appy.12539
Journal - Research Article
Kremer, L. J., Medlicott, N., Sime, M. J., Broadbent, R., Edmonds, L., Berry, M. J., Austin, N. C., … Reith, D. M. (2023). Low dose or very low dose phenylephrine and cyclopentolate microdrops for retinopathy of prematurity eye examinations (The Little Eye Drop Study): A randomised controlled non-inferiority trial. Archives of Disease in Childhood: Fetal & Neonatal Edition, 108, F380-F386. doi: 10.1136/archdischild-2022-324929
Journal - Research Article
Kremer, L., Reith, D., Medlicott, N. J., Sime, M. J., Edmonds, L., & Broadbent, R. (2022). A survey of neonatal nurses on mydriatic regimens used in neonatal retinopathy of prematurity eye examinations. American Journal of Perinatology, 39(16), 1779-1785. doi: 10.1055/s-0041-1726316
Journal - Research Article
Kremer, L. J., Broadbent, R., Medlicott, N., Sime, M. J., McCaffrey, F., & Reith, D. M. (2021). Randomised controlled pilot trial comparing low dose and very low- dose microdrop administration of phenylephrine and cyclopentolate for retinopathy of prematurity eye examinations in neonates. Archives of Disease in Childhood, 106, 603-608. doi: 10.1136/archdischild-2019-318733
Journal - Research Article
Porter, G. C., Safii, S. H., Medlicott, N. J., Duncan, W. J., Tompkins, G. R., & Coates, D. E. (2021). Formulation of a semisolid emulsion containing Leptospermum scoparium essential oil and evaluation of in vitro antimicrobial and antibiofilm efficacy. Planta Medica, 87, 253-266. doi: 10.1055/a-1330-8765
Journal - Research Article
Glue, P., Medlicott, N. J., Neehoff, S., Surman, P., Lam, F., Hung, N., & Hung, C.-T. (2020). Safety and efficacy of extended release ketamine tablets in patients with treatment-resistant depression and anxiety: Open label pilot study. Therapeutic Advances in Psychopharmacology, 10, 1-6. doi: 10.1177/2045125320922474
Journal - Research Article
Glue, P., Medlicott, N. J., Surman, P., Lam, F., Hung, N., & Hung, C. T. (2020). Ascending-dose study of controlled-release ketamine tablets in healthy volunteers: Pharmacokinetics, pharmacodynamics, safety, and tolerability. Journal of Clinical Pharmacology, 60(6), 751-757. doi: 10.1002/jcph.1573
Journal - Research Article
Glue, P., Neehoff, S., Sabadel, A., Broughton, L., Le Nedelec, M., Shadli, S., McNaughton, N., & Medlicott, N. J. (2020). Effects of ketamine in patients with treatment-refractory generalized anxiety and social anxiety disorders: Exploratory double-blind psychoactive-controlled replication study. Journal of Psychopharmacology, 34(3), 267-272. doi: 10.1177/0269881119874457
Journal - Research Article
Porter, G. C., Schwass, D. R., Tompkins, G. R., Bobbala, S. K. R., Medlicott, N. J., & Meledandri, C. J. (2020). AgNP/Alginate Nanocomposite hydrogel for antimicrobial and antibiofilm applications. Carbohydrate Polymers, 251, 117017. doi: 10.1016/j.carbpol.2020.117017
Journal - Research Article
Simpson, B. H., Reith, D. M., Medlicott, N. J., & Smith, A. J. (2020). Monitoring the use of dabigatran etexilate for stroke prevention: Compliance with renal function guidelines. Journal of Primary Health Care, 12(4), 327-334. doi: 10.1071/HC19115
Journal - Research Article
Abdul Aziz, Y. H., Al-Sallami, H. S., Wiltshire, E., Rayns, J., Willis, J., McClintock, J., Medlicott, N., Wheeler, B. J., the Paediatric Society of New Zealand Diabetes Clinical Network. (2019). Insulin pump initiation and education for children and adolescents: A qualitative study of current practice in New Zealand. Journal of Diabetes & Metabolic Disorders, 18, 59-64. doi: 10.1007/s40200-019-00390-6
Journal - Research Article
Dowd, L. A., Wheeler, B. J., Al-Sallami, H. S., Broadbent, R. S., Edmonds, L. K., & Medlicott, N. J. (2019). Paracetamol treatment for patent ductus arteriosus: Practice and attitudes in Australia and New Zealand. Journal of Maternal-Fetal & Neonatal Medicine, 32(18), 3039-3044. doi: 10.1080/14767058.2018.1456520
Journal - Research Article
Kremer, L. J., Reith, D. M., Medlicott, N., & Broadbent, R. (2019). Systematic review of mydriatics used for screening of retinopathy in premature infants. BMJ Paediatrics Open, 3(1), 3000448. doi: 10.1136/bmjpo-2019-000448
Journal - Research Article
Ritchie, D., Broadbent, R., Medlicott, N., & Reith, D. M. (2019). In vitro validation of a method for neonatal urine collection and analysis. BMJ Paediatrics Open, 3(1), e000482. doi: 10.1136/bmjpo-2019-000482
Journal - Research Article
Simpson, B. H., Reith, D. M., Medlicott, N. J., & Smith, A. J. (2019). Exposure response supports therapeutic drug monitoring for dabigatran etexilate in patients with atrial fibrillation. TH Open, 3(3), e210-e215. doi: 10.1055/s-0039-1693486
Journal - Research Article
Thew, J., Burrage, P., Medlicott, N., & Mallet, D. (2019). Modelling optimal delivery of bFGF to chronic wounds using ODEs. Journal of Theoretical Biology, 465, 109-116. doi: 10.1016/j.jtbi.2018.12.028
Journal - Research Article
Glue, P., Neehoff, S. M., Medlicott, N. J., Gray, A., Kibby, G., & McNaughton, N. (2018). Safety and efficacy of maintenance ketamine treatment in patients with treatment-refractory generalised anxiety and social anxiety disorders. Journal of Psychopharmacology, 32(6), 663-667. doi: 10.1177/0269881118762073
Journal - Research Article
Le Nedelec, M., Glue, P., Winter, H., Goulton, C., & Medlicott, N. J. (2018). The effect of route of administration on the enantioselective pharmacokinetics of ketamine and norketamine in rats. Journal of Psychopharmacology, 32(10), 1127-1132. doi: 10.1177/0269881118780013
Journal - Research Article
Le Nedelec, M., Glue, P., Winter, H., Goulton, C., Broughton, L., & Medlicott, N. (2018). Acute low-dose ketamine produces a rapid and robust increase in plasma BDNF without altering brain BDNF concentrations. Drug Delivery & Translational Research, 8(3), 780-786. doi: 10.1007/s13346-017-0476-2
Journal - Research Article
Muller, M., Wheeler, B. J., Blackwell, M., Colas, M., Reith, D. M., Medlicott, N. J., & Al-Sallami, H. S. (2018). The influence of patient variables on insulin total daily dose in paediatric inpatients with new onset type 1 diabetes mellitus. Journal of Diabetes & Metabolic Disorders, 17, 159-163. doi: 10.1007/s40200-018-0355-5
Journal - Research Article
Simpson, B. H., Reith, D. M., Medlicott, N. J., & Smith, A. J. (2018). Choice of renal function estimator influences adverse outcomes with dabigatran etexilate in patients with atrial fibrillation. TH Open, 2(04), e420-e427. doi: 10.1055/s-0038-1676356. ISSN 2512-9465
Journal - Research Article
Simpson, B. H., Reith, D., Medlicott, N. J., & Smith, A. (2018). Deprivation and inequalities lead to worse outcomes with dabigatran etexilate. Journal of Primary Health Care, 10(4), 303-311. doi: 10.1071/HC17081
Journal - Research Article
Smith, A. J., Scahill, S. L., Harrison, J., Carroll, T., & Medlicott, N. J. (2018). Service provision in the wake of a new funding model for community pharmacy. BMC Health Services Research, 18, 307. doi: 10.1186/s12913-018-3120-z
Journal - Research Article
Zeeshan, F., Tabbassum, M., Jorgensen, L., & Medlicott, N. J. (2018). Attenuated total reflection Fourier transform infrared (ATR FT-IR) spectroscopy as an analytical method to investigate the secondary structure of a model protein embedded in solid lipid matrices. Applied Spectroscopy, 72(2), 268-279. doi: 10.1177/0003702817739908
Journal - Research Article
Apperley, O., Medlicott, N., Rich, A., Hanning, S., & Huckabee, M. L. (2017). A clinical trial of a novel emulsion for potential use as a saliva substitute in patients with radiation induced xerostomia. Journal of Oral Rehabilitation, 44(11), 889-895. doi: 10.1111/joor.12545
Journal - Research Article
Glue, P., Medlicott, N. J., Harland, S., Neehoff, S., Anderson-Fahey, B., Le Nedelec, M., Gray, A., & McNaughton, N. (2017). Ketamine's dose-related effects on anxiety symptoms in patients with treatment refractory anxiety disorders. Journal of Psychopharmacology, 31(10), 1302-1305. doi: 10.1177/0269881117705089
Journal - Research Article
Salis, E. R., Reith, D. M., Wheeler, B. J., Broadbent, R. S., & Medlicott, N. J. (2017). Hyperglycaemic preterm neonates exhibit insulin resistance and low insulin production. BMJ Paediatrics Open, 1(1), e000160. doi: 10.1136/ bmjpo-2017-000160
Journal - Research Article
Salis, E. R., Reith, D. M., Wheeler, B. J., Broadbent, R. S., & Medlicott, N. J. (2017). Insulin resistance, glucagon-like peptide-1 and factors influencing glucose homeostasis in neonates. Archives of Disease in Childhood: Fetal & Neonatal Edition, 102(2), F162-F166. doi: 10.1136/archdischild-2015-309174
Journal - Research Article
Hanning, S. M., & Medlicott, N. J. (2016). Oil-based compositions as saliva substitutes: A pilot study to investigate in-mouth retention. International Journal of Pharmaceutics, 501, 265-270. doi: 10.1016/j.ijpharm.2016.01.058
Journal - Research Article
Linakis, M. W., Roberts, J. K., Lala, A. C., Spigarelli, M. G., Medlicott, N. J., Reith, D. M., … Sherwin, C. M. T. (2016). Challenges associated with route of administration in neonatal drug delivery. Clinical Pharmacokinetics, 55(2), 185-196. doi: 10.1007/s40262-015-0313-z
Journal - Research Article
Salis, E. R., Reith, D. M., Broadbent, R. S., & Medlicott, N. J. (2016). Haematocrit influences insulin concentration measurements in dried blood spots. Journal of Maternal-Fetal & Neonatal Medicine, 29(19), 3208-3211. doi: 10.3109/14767058.2015.1119116
Journal - Research Article
Salis, E. R., Soelbeck, M. K., Reith, D. M., Wheeler, B. J., Broadbent, R. S., & Medlicott, N. J. (2016). Effect of gestational age and blood glucose on C-peptide excretion rate and clearance in neonates. Journal of Paediatrics & Child Health, 52(1), 60-66. doi: 10.1111/jpc.12977
Journal - Research Article
Al-Sallami, H. S., & Medlicott, N. J. (2015). Investigation of an anti-activated factor X (anti-Xa) assay for the quantification of enoxaparin in human plasma. Journal of Pharmacy & Pharmacology, 67(2), 209-214. doi: 10.1111/jphp.12333
Journal - Research Article
Kanjanakawinkul, W., Medlicott, N. J., Rades, T., Puttipipatkhachorn, S., & Pongjanyakul, T. (2015). Lysozyme–magnesium aluminum silicate microparticles: Molecular interaction, bioactivity and release studies. International Journal of Biological Macromolecules, 80, 651-658. doi: 10.1016/j.ijbiomac.2015.07.033
Journal - Research Article
Madsen, C. G., Skov, A., Baldursdottir, S., Rades, T., Jorgensen, L., & Medlicott, N. J. (2015). Simple measurements for prediction of drug release from polymer matrices: Solubility parameters and intrinsic viscosity. European Journal of Pharmaceutics & Biopharmaceutics, 92, 1-7. doi: 10.1016/j.ejpb.2015.02.001
Journal - Research Article
Owens, K. H., Medlicott, N. J., Zacharias, M., Whyte, I. M., Buckley, N. A., & Reith, D. M. (2015). Population pharmacokinetic-pharmacodynamic modelling to describe the effects of paracetamol and N-acetylcysteine on the international normalized ratio. Clinical & Experimental Pharmacology & Physiology, 42(1), 102-108. doi: 10.1111/1440-1681.12327
Journal - Research Article
Symon, V., Heydon, S., Medlicott, N. J., Kieser, J., & Fleming, J. S. (2015). Before CSI: Making the case for a novel portrayal of forensic science. International Journal of Science in Society, 6, 7-15.
Journal - Research Article
Hanning, S. M., Kieser, J. A., Ferguson, M. M., Reid, M., & Medlicott, N. J. (2014). The use of lithium as a marker for the retention of liquids in the oral cavity after rinsing. Clinical Oral Investigations, 18(5), 1533-1537. doi: 10.1007/s00784-013-1141-x
Journal - Research Article
McDowell, A., Fothergill, J. A., Khan, A., & Medlicott, N. J. (2014). A cyclodextrin formulation to improve use of the anesthetic tribromoethanol (Avertin®). Journal of Pharmacy & BioAllied Sciences, 6(1), 16-21. doi: 10.4103/0975-7406.124303
Journal - Research Article
Owens, K. H., Murphy, P. G. M., Medlicott, N. J., Kennedy, J., Zacharias, M., Curran, N., Sreebhavan, S., Thompson-Fawcett, M., & Reith, D. M. (2014). Population pharmacokinetics of intravenous acetaminophen and its metabolites in major surgical patients. Journal of Pharmacokinetics & Pharmacodynamics, 41(3), 211-221. doi: 10.1007/s10928-014-9358-0
Journal - Research Article
Sherwin, C. M. T., Medlicott, N. J., Reith, D. M., & Broadbent, R. S. (2014). Intravenous drug delivery in neonates: Lessons learnt. Archives of Disease in Childhood, 99, 590-594. doi: 10.1136/archdischild-2013-304887
Journal - Research Article
Hanning, S. M., Yu, T., Jones, D. S., Andrews, G. P., Kieser, J. A., & Medlicott, N. J. (2013). Lecithin-based emulsions for potential use as saliva substitutes in patients with xerostomia: Viscoelastic properties. International Journal of Pharmaceutics, 456(2), 560-568. doi: 10.1016/j.ijpharm.2013.08.009
Journal - Research Article
Medlicott, N. J., Reith, D. M., McCaffrey, F., Krittaphol, W., & Broadbent, R. S. (2013). Delayed delivery of intravenous gentamicin in neonates: Impact of infusion variables. Journal of Pharmacy & Pharmacology, 65(3), 370-378. doi: 10.1111/jphp.12000
Journal - Research Article
Hanning, S., Motoi, L., Medlicott, N., & Swindells, S. (2012). A device for the collection of submandibular saliva. New Zealand Dental Journal, 108(1), 4-8.
Journal - Research Article
Owens, K. H., Medlicott, N. J., Zacharias, M., Chary, S., Thompson-Fawcett, M., & Reith, D. M. (2012). The pharmacokinetic profile of intravenous paracetamol in adult patients undergoing major abdominal surgery. Therapeutic Drug Monitoring, 34(6), 713-721. doi: 10.1097/FTD.0b013e31826a70ea
Journal - Research Article
Pinholt, C., Hartvig, R. A., Medlicott, N. J., & Jorgensen, L. (2011). The importance of interfaces in protein drug delivery: Why is protein adsorption of interest in pharmaceutical formulations? Expert Opinion on Drug Delivery, 8(7), 949-964. doi: 10.1517/17425247.2011.577062
Journal - Research Article
Wu, Z., Tucker, I. G., Razzak, M., McSporran, K., & Medlicott, N. J. (2010). Tissue compatibility and pharmacokinetics of three potential subcutaneous injectables for low-pH drug solutions. Journal of Pharmacy & Pharmacology, 62(7), 873-882. doi: 10.1211/jpp.62.07.0008
Journal - Research Article
Wu, Z., Tucker, I. G., Razzak, M., Yang, L., McSporran, K., & Medlicott, N. J. (2010). Absorption and tissue tolerance of ricobendazole in the presence of hydroxypropyl-β-cyclodextrin following subcutaneous injection in sheep. International Journal of Pharmaceutics, 397, 96-102. doi: 10.1016/j.ijpharm.2010.07.002
Journal - Research Article
Braund, R., Hook, S. M., Greenhill, N., & Medlicott, N. J. (2009). Distribution of fibroblast growth factor-2 (FGF-2) within model excisional wounds following topical application. Journal of Pharmacy & Pharmacology, 61(2), 193-200. doi: 10.1211/jpp/61.02.0008
Journal - Research Article
Reith, D., Medlicott, N. J., De Silva, R. K., Yang, L., Hickling, J., & Zacharias, M. (2009). Simultaneous modelling of the Michaelis-Menten kinetics of paracetamol sulphation and glucuronidation. Clinical & Experimental Pharmacology & Physiology, 36(1), 35-42. doi: 10.1111/j.1440-1681.2008.05029.x
Journal - Research Article
Sherwin, C. M. T., Kostan, E., Broadbent, R. S., Medlicott, N. J., & Reith, D. M. (2009). Evaluation of the effect of intravenous volume expanders upon the volume of distribution of gentamicin in septic neonates. Biopharmaceutics & Drug Disposition, 30(5), 276-280. doi: 10.1002/bdd.666
Journal - Research Article
Sherwin, C. M. T., McCaffrey, F., Broadbent, R. S., Reith, D. M., & Medlicott, N. J. (2009). Discrepancies between predicted and observed rates of intravenous gentamicin delivery for neonates. Journal of Pharmacy & Pharmacology, 61(4), 465-471. doi: 10.1211/jpp/61.04.0008
Journal - Research Article
Sherwin, C. M. T., Svahn, S., Van Der Linden, A., Broadbent, R. S., Medlicott, N. J., & Reith, D. M. (2009). Individualised dosing of amikacin in neonates: A pharmacokinetic/pharmacodynamic analysis. European Journal of Clinical Pharmacology, 65(7), 705-713. doi: 10.1007/s00228-009-0637-4
Journal - Research Article
Tantipolphan, R., Rades, T., & Medlicott, N. J. (2009). Swelling lecithin: Cholesterol implants for the controlled release of proteins. Journal of Liposome Research, 19(1), 37-48. doi: 10.1080/08982100802636434
Journal - Research Article
Wu, Z., Tucker, I. G., Razzak, M., & Medlicott, N. J. (2009). Stability of ricobendazole in aqueous solutions. Journal of Pharmaceutical & Biomedical Analysis, 49(5), 1282-1286. doi: 10.1016/j.jpba.2009.02.032
Journal - Research Article
Al-Sallami, H., Ferguson, R., Wilkins, G., Gray, A., & Medlicott, N. J. (2008). Bleeding events in patients receiving enoxaparin for the management of non-ST-elevation acute coronary syndrome (NSTEACS) at Dunedin Public Hospital, New Zealand. New Zealand Medical Journal, 121(1285). Retrieved from http://journal.nzma.org.nz/journal/121-1285/3342/content.pdf
Journal - Research Article
Sherwin, C. M. T., Broadbent, R. S., Medlicott, N. J., & Reith, D. M. (2008). Individualising netilmicin dosing in neonates. European Journal of Clinical Pharmacology, 64, 1201-1208. doi: 10.1007/s00228-008-0536-0
Journal - Research Article
Sherwin, C., Broadbent, R., Young, S., Worth, J., McCaffrey, F., Medlicott, N. J., & Reith, D. (2008). Utility of interleukin-12 and interleukin-10 in comparison with other cytokines and acute-phase reactants in the diagnosis of neonatal sepsis. American Journal of Perinatology, 25, 629-636. doi: 10.1055/s-0028-1090585
Journal - Research Article
Tantipolphan, R., Rades, T., & Medlicott, N. J. (2008). Insights into the structure of protein by vibrational spectroscopy. Current Pharmaceutical Analysis, 4, 53-68.
Journal - Research Article
Braund, R., Hook, S., & Medlicott, N. J. (2007). The role of topical growth factors in chronic wounds. Current Drug Delivery, 4(3), 195-204. doi: 10.2174/156720107781023857
Journal - Research Article
Braund, R., Tucker, I. G., & Medlicott, N. J. (2007). Hypromellose films for the delivery of growth factors for wound healing. Journal of Pharmacy & Pharmacology, 59(3), 367-372.
Journal - Research Article
Tantipolphan, R., Rades, T., McQuillan, A. J., & Medlicott, N. J. (2007). Adsorption of bovine serum albumin (BSA) onto lecithin studied by attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy. International Journal of Pharmaceutics, 337, 40-47.
Journal - Research Article
Zacharias, M., De Silva, R. K., Hickling, J., Medlicott, N. J., & Reith, D. M. (2007). Comparative safety and efficacy of two high dose regimens of oral paracetamol in healthy adults undergoing third molar surgery under local anaesthesia. Anaesthesia & Intensive Care, 35(4), 544-549.
Journal - Research Article
Milak, S., Medlicott, N., & Tucker, I. G. (2006). Solid lipid microparticles containing loratadine prepared using a Micromixer. Journal of Microencapsulation, 23(8), 823-831.
Journal - Research Article
Tantipolphan, R., Rades, T., Strachan, C. J., Gordon, K. C., & Medlicott, N. J. (2006). Analysis of lecithin-cholesterol mixtures using Raman spectroscopy. Journal of Pharmaceutical & Biomedical Analysis, 41, 476-484.
Journal - Research Article
Wu, Z., Medlicott, N. J., Razzak, M., & Tucker, I. G. (2005). Development and optimization of a rapid HPLC method for analysis of ricobendazole and albendazole sulfone in sheep plasma. Journal of Pharmaceutical & Biomedical Analysis, 39(5), 225-232.
Journal - Research Article
Wu, Z., Razzak, M., Tucker, I. G., & Medlicott, N. J. (2005). Physicochemical characterization of ricobendazole: I. Solubility, lipophilicity, and ionization characteristics. Journal of Pharmaceutical Sciences, 94(5), 983-993.
Journal - Research Article
Wu, Z., Tucker, I. G., Razzak, M., & Medlicott, N. J. (2005). An in vitro kinetic method for detection of precipitation of poorly soluble drugs. International Journal of Pharmaceutics, 304, 1-3.
Journal - Research Article
Medlicott, N. J., Waldron, N. A., & Foster, T. P. (2004). Sustained release veterinary parenteral products. Advanced Drug Delivery Reviews, 56, 1345-1365.
Journal - Research Article
Pongjanyakul, T., Medlicott, N. J., & Tucker, I. G. (2004). Melted glyceryl palmitostearate (GPS) pellets for protein delivery. International Journal of Pharmaceutics, 271, 53-62.
Journal - Research Article
Slobbe, L., Medlicott, N., Lockhart, E., Davies, N., Tucker, I., Razzak, M., & Buchan, G. (2003). A prolonged immune response to antigen delivered in poly (∈-caprolactone) microparticles. Immunology & Cell Biology, 81, 185-191. doi: 10.1046/j.1440-1711.2003.01155.x
Journal - Research Article
Medlicott, N. J., Holborow, D. W., Rathbone, M. J., Jones, D. S., & Tucker, I. G. (1999). Local delivery of chlorhexidine using a tooth-bonded delivery system. Journal of Controlled Release, 61(3), 337-343. doi: 10.1016/S0168-3659(99)00152-2
Journal - Research Article
Medlicott, N. J., Foster, K. A., Audus, K. L., Gupta, S., & Stella, V. J. (1998). Comparison of the effects of potential parenteral vehicles for poorly water soluble anticancer drugs (organic cosolvents and cyclodextrin solutions) on cultered endothelial cells (HUV-EC). Journal of Pharmaceutical Sciences, 87, 1138-1143.
Journal - Research Article
Medlicott, N. J., Tucker, I. G., Rathbone, M. J., Holborow, D. W., & Jones, D. J. (1996). Chlorhexidine release from poly (ε-caprolactone) films prepared by solvent evaporation. International Journal of Pharmaceutics, 143(1), 25-35. doi: 10.1016/S0378-5173(96)04675-3
Journal - Research Article
Medlicott, N. J., Tucker, I. G., Holborow, D. W., & Rathbone, M. J. (1995). Liquid chromatographic analysis of chlorhexidine at specific sites in the saliva film after application of a tooth-bonded delivery system. Journal of Liquid Chromatography, 18(11), 2193-2204. doi: 10.1080/10826079508010264
Journal - Research Article
Woods, S. J., Hughes-Medlicott, N. J., & McDowell, A. (2023). Pharmacokinetics in penguins compared to other avian species: A review of enrofloxacin and voriconazole. Molecular Pharmaceutics. Advance online publication. doi: 10.1021/acs.molpharmaceut.3c00520
Journal - Research Other
Ameratunga, R., Woon, S.-T., Steele, R., Snell, R., Medlicott, N., Mears, E., … Das, S., … Quiñones‑Mateu, M. E. (2021). The nose and the stomach play a critical role in the NZACE2-Pātari* (modified ACE2) drug treatment project of SARS-CoV-2 infection. Expert Review of Clinical Immunology, 17(6), 553-560. doi: 10.1080/1744666x.2021.1912596
Journal - Research Other
Broughton, L. C., Medlicott, N. J., & Smith, A. J. (2021). Effectiveness of patient decision aids in women considering psychotropic medication use during pregnancy: A literature review. Archives of Women's Mental Health, 24, 569-578. doi: 10.1007/s00737-021-01118-3
Journal - Research Other
Glue, P., Russell, B., & Medlicott, N. J. (2021). Influence of formulation and route of administration on ketamine's safety and tolerability: Systematic review. European Journal of Clinical Pharmacology, 77, 671-676. doi: 10.1007/s00228-020-03047-z
Journal - Research Other
Kremer, L., Reith, D., Medlicott, N. J., Sime, M. J., Edmonds, L., & Broadbent, R. (2021). Microdrop administration of mydriatics may reduce the risk of NEC. Pediatrics International, 63(6), 741. doi: 10.1111/ped.14620
Journal - Research Other
Ameratunga, R., Lehnert, K., Leung, E., Comoletti, D., Snell, R., Woon, S.-T., … Medlicott, N., Das, S., … Quiñones‑Mateu, M., … Jordan, A. (2020). Inhaled modified angiotensin converting enzyme 2 (ACE2) as a decoy to mitigate SARS-CoV-2 infection. New Zealand Medical Journal, 133(1515), 112-118. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Other
Lala, A. C., Broadbent, R. S., Medlicott, N. J., Sherwin, C. M. T., & Reith, D. M. (2015). Illustrative neonatal cases regarding drug delivery issues. Journal of Paediatrics & Child Health, 51, 478-481. doi: 10.1111/jpc.12764
Journal - Research Other
Al-Sallami, H., Jordan, S., Ferguson, R., Medlicott, N. J., Schollum, J., & Duffull, S. B. (2010). Current enoxaparin dosing guidelines have dubious credibility [Viewpoint]. New Zealand Medical Journal, 123(1313). Retrieved from http://journal.nzma.org.nz/journal/123-1313/4076/content.pdf
Journal - Research Other
Sherwin, C. M. T., Broadbent, R. S., Medlicott, N. J., & Reith, D. M. (2009). Individualised dosing of amikacin in neonates [Letter to the editor]. European Journal of Clinical Pharmacology, 65(12), 1267-1268. doi: 10.1007/s00228-009-0691-y
Journal - Research Other
Sherwin, C. M. T., Svahn, S., Broadbent, R. S., Van Der Linden, A., Medlicott, N. J., & Reith, D. M. (2008). Netilmicin withdrawal: Impact on neonates [Letter]. New Zealand Medical Journal, 121(1284). Retrieved from http://journal.nzma.org.nz/journal/121-1284/3328/content.pdf
Journal - Research Other
Medlicott, N. J., & Tucker, I. G. (1999). Pulsatile release from subcutaneous implants. Advanced Drug Delivery Reviews, 38, 139-149. doi: 10.1016/S0169-409X(99)00013-7
Journal - Research Other