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Personnel

Research interests

My research focuses on investigating the mechanisms that underlie heart failure and vascular disease particularly in the context of hypertension and diabetes. To this end, we have developed a number of novel tools to assess cardiovascular signaling pathways.

These include:

  • FRET-based biosensors to measure kinase activity and localization in living cells
  • Custom antibodies to measure biochemical modifications of proteins
  • A variety of animal models with enhanced or reduced susceptibility to cardiovascular pathology.

With this research, we hope to contribute new understanding to the molecular basis of cardiovascular signaling that will culminate in potential clinical therapies for heart disease and atherosclerosis.

Projects

  • Identifying the mechanism by which CaMKII regulates cellular signaling in the diabetic heart
  • The role of CaMKII in vascular physiology and pathology
  • Nitric oxide as a mediator of cardiac signaling

Current funding

  • Health Research Council Project Grant
  • Royal Society of New Zealand Marsden Fast Start Research Grant
  • University of Otago Research Grant

Previous funding

  • American Heart Association Scientist Development Grant
  • National Institute of Health T32 Fellowship

Publications

Katare, R., Erickson, J. R., & Schwenke, D. O. (2026). Ghrelin protects against cell death in myocardial ischaemia: Emerging role of microRNA. Experimental Physiology. Advance online publication. doi: 10.1113/ep093314 Journal - Research Other

Sethi, S., Cheong, I., Bussey, C. T., Schwenke, D. O., Erickson, J. R., Brown, C., & Lamberts, R. R. (2026). Central regulation of the heart in type 2 diabetes mellitus. Journal of Molecular & Cellular Cardiology, 211. doi: 10.1016/j.yjmcc.2025.11.012 Journal - Research Article

Murrell, C. L., Barad, Z., Wallace, R. S., Erickson, J. R., Brown, C. H., & Augustine, R. A. (2025). Mapping O-linked glycosylation in the rat hypothalamus in pregnancy and lactation. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.70076 Journal - Research Article

Asamudo, E. U., Parackal, R. E., Erickson, J. R., & Bers, D. M. (2025). S-nitrosylation of cardiac myocyte proteins may underlie sex differences in cardiac disease. Frontiers in Physiology, 16, 1565917. doi: 10.3389/fphys.2025.1565917 Journal - Research Other

Anscombe, M. J., Jones, P. P., & Erickson, J. R. (2024, August-September). HEK293-RyR2 cells as a model for cardiac arrhythmia in high throughput screening. Poster session presented at the 18th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)

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