2026
Journal - Research Other
Theobald, P., Harding, A. J., Taylor, M., Donovan, K., Moltchanova, E., Stevens, A., Tikao, K., … Rucklidge, J. J. (2026). Efficacy of oral micronutrients and online mindfulness for emotional dysregulation in children aged 6–10 (The M&M Trial): A randomized, double-blind, placebo-controlled trial. Nutritional Psychiatry, 2, 100014. doi: 10.1016/j.nupsyc.2026.100014
2025
Journal - Research Article
Mock, P. Y., Chua, E. W., Stevens, A., Salim, F., & Lam, K. W. (2025). Exploration of chromenone-based ligands as DNA G-quadruplex targets in triple-negative breast cancer. Bioorganic Chemistry, 166, 109150. doi: 10.1016/j.bioorg.2025.109150
Stevens, A. J., Kennedy, M. A., Doudney, K., Kidd, M. J. A., & Rucklidge, J. J. (2025). Potential link between copy number variation and abnormal genome wide DNA methylation profile in an individual with severe ADHD and a strong response to micronutrient treatment. Psychiatry Research Case Reports. Advance online publication. doi: 10.1016/j.psycr.2025.100254
Journal - Research Other
Damiano, O. M., Stevens, A. J., Kenwright, D. N., & Seddon, A. R. (2025). Chronic inflammation to cancer: The impact of oxidative stress on DNA methylation. Frontiers in Bioscience - Landmark, 30(3), 26142. doi: 10.31083/fbl26142
2024
Journal - Research Article
Stevens, A. J., Heiwari, T. M., Rich, F. J., Bradley, H. A., Gur, T. L., Galley, J. D., Kennedy, M. A., … Mulder, R. T., & Rucklidge, J. J. (2024). Randomised control trial indicates micronutrient supplementation may support a more robust maternal microbiome for women with antenatal depression during pregnancy. Clinical Nutrition, 3, 120-132. doi: 10.1016/j.clnu.2024.09.004
Seddon, A. R., Damiano, O., Hampton, M. B., & Stevens, A. J. (2024). Widespread genomic de novo DNA methylation occurs following CD8+ T cell activation and proliferation. Epigenetics, 19(1), 2367385. doi: 10.1080/15592294.2024.2367385
Picard, L. C., Rich, F. J., Kenwright, D. N., & Stevens, A. J. (2024). Epigenetic changes associated with Bacillus Calmette-Guerin (BCG) treatment in bladder cancer. Biochimica et Biophysica Acta: Reviews on Cancer, 1879, 189123. doi: 10.1016/j.bbcan.2024.189123
Journal - Research Other
Seddon, A. R., MacArthur, C. P., Hampton, M. B., & Stevens, A. J. (2024). Inflammation and DNA methylation in Alzheimer’s disease: Mechanisms of epigenetic remodelling by immune cell oxidants in the ageing brain. Redox Report, 29(1), 2428152. doi: 10.1080/13510002.2024.2428152
Conference Contribution - Published proceedings: Abstract
Damiano, O. M., Stevens, A. J., Seddon, A. R., & Chatterjee, A. (2024). Altered DNA methylation patterns in colorectal cancer associated with immune cell oxidants. Proceedings of the 17th GeneMappers Conference. Retrieved from https://www.genemappersconference.org
Picard, L. C., Rich, F., & Stevens, A. J. (2024). Epigenetic consequences of BCG-activated leukocytes on bladder cancer cells. Proceedings of the 17th GeneMappers Conference. Retrieved from https://www.genemappersconference.org
Stevens, A., Seddon, A., Hampton, M., & Andrew, D. (2024). Oxidative stress induced changes in DNA methylation. Proceedings of the 17th GeneMappers Conference. Retrieved from https://www.genemappersconference.org
Seddon, A., Das, A., Hampton, M., & Stevens, A. (2024). Understanding how immune oxidants can drive epigenetic change. European Journal of Human Genetics, 32(Suppl. 1), (pp. 720). doi: 10.1038/s41431-023-01482-x
2023
Journal - Research Article
Seddon, A. R., Das, A. B., Hampton, M. B., & Stevens, A. J. (2023). Site-specific decreases in DNA methylation in replicating cells following exposure to oxidative stress. Human Molecular Genetics, 32(4), 632-648. doi: 10.1093/hmg/ddac232
Journal - Research Other
Yan, M. P., Wee, C. E., Yen, K. P., Stevens, A., & Wai, L. K. (2023). G-quadruplex ligands as therapeutic agents against cancer, neurological disorders and viral infections. Future Medicinal Chemistry, 15(21), 1987-2009. doi: 10.4155/fmc-2023-0202
He, Z., Wilson, A., Rich, F., Kenwright, D., Stevens, A., Low, Y. S., & Thunders, M. (2023). Chromosomal instability and its effect on cell lines. Cancer Reports, 6, e1822. doi: 10.1002/cnr2.1822
2022
Journal - Research Other
Stevens, A. J., de Jong, L., & Kennedy, M. A. (2022). The dynamic regulation of G-quadruplex DNA structures by cytosine methylation. International Journal of Molecular Sciences, 23, 2407. doi: 10.3390/ijms23052407
2021
Journal - Research Article
Seddon, A. R., Liau, Y., Pace, P. E., Miller, A. L., Das, A. B., Kennedy, M. A., Hampton, M. B., & Stevens, A. J. (2021). Genome-wide impact of hydrogen peroxide on maintenance DNA methylation in replicating cells. Epigenetics & Chromatin, 14(1), 17. doi: 10.1186/s13072-021-00388-6
2020
Journal - Research Article
Heft, I. E., Mostovoy, Y., Levy-Sakin, M., Ma, W., Stevens, A. J., Pastor, S., … Kennedy, M. A., … Sikela, J. M. (2020). The driver of extreme human-specific Olduvai repeat expansion remains highly active in the human genome. Genetics, 214, 179-191. doi: 10.1534/genetics.119.302782
Conference Contribution - Published proceedings: Abstract
Das, A. B., O'Connor, K. M., Stevens, A. J., Seddon, A. R., & Winterbourn, C. C. (2020). Immune cell oxidants inhibit DNA methylation in proliferating cells [Invited]. Proceedings of the Genetics Otago (GO) Epigenetics User Group (EUG) Symposium. Retrieved from https://blogs.otago.ac.nz/go/2020-3/
2019
Journal - Research Article
Stevens, A. J., Purcell, R. V., Darling, K. A., Eggleston, M. J. F., Kennedy, M. A., & Rucklidge, J. J. (2019). Human gut microbiome changes during a 10 week randomised control trial for micronutrient supplementation in children with attention deficit hyperactivity disorder. Scientific Reports, 9, 10128. doi: 10.1038/s41598-019-46146-3
Rucklidge, J. J., Eggleston, M. J. F., Darling, K., Stevens, A., Kennedy, M., & Frampton, C. M. (2019). Can we predict treatment response in children with ADHD to a vitamin-mineral supplement? An investigation into pre-treatment nutrient serum levels, MTHFR status, clinical correlates and demographic variables. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 89, 181-192. doi: 10.1016/j.pnpbp.2018.09.007
2018
Journal - Research Article
Stevens, A. J., Rucklidge, J. J., Darling, K. A., Eggleston, M. J. F., Pearson, J. F., & Kennedy, M. A. (2018). Methylomic changes in response to micronutrient supplementation and MTHFR genotype. Epigenomics, 10(9), 1201-1214. doi: 10.2217/epi-2018-0029
Stevens, A. J., Rucklidge, J. J., & Kennedy, M. A. (2018). Epigenetics, nutrition and mental health: Is there a relationship? [Review]. Nutritional Neuroscience, 21(9), 602-613. doi: 10.1080/1028415x.2017.1331524
2017
Journal - Research Article
Stevens, A. J., & Kennedy, M. A. (2017). Methylated cytosine maintains G-quadruplex structures during polymerase chain reaction and contributes to allelic dropout. Biochemistry, 56(29), 3691-3698. doi: 10.1021/acs.biochem.7b00480
Stevens, A. J., Taylor, M. G., Pearce, F. G., & Kennedy, M. A. (2017). Allelic dropout during polymerase chain reaction due to G-quadruplex structures and DNA methylation is widespread at imprinted human loci. Genes Genomes Genetics, 7(3), 1019-1025. doi: 10.1534/g3.116.038687
Stevens, A. J., & Kennedy, M. A. (2017). Structural analysis of G-quadruplex formation at the human MEST promoter. PLoS ONE, 12(1), e0169433. doi: 10.1371/journal.pone.0169433
2016
Journal - Research Article
Steel, O., Kraberger, S., Sikorski, A., Young, L. M., Catchpole, R. J., Stevens, A. J., … Varsani, A. (2016). Circular replication-associated protein encoding DNA viruses identified in the faecal matter of various animals in New Zealand. Infection, Genetics & Evolution, 43, 151-164. doi: 10.1016/j.meegid.2016.05.008
Stevens, A. J., Kennedy, H. L., & Kennedy, M. A. (2016). Fluorescence methods for probing G-quadruplex structure in single- and double-stranded DNA. Biochemistry, 55(26), 3714-3725. doi: 10.1021/acs.biochem.6b00327
Journal - Research Other
Stevens, A. J., Appleby, S., & Kennedy, M. A. (2016). Many commercial hot-start polymerases demonstrate activity prior to thermal activation. Biotechniques, 61(6), 293-296. doi: 10.2144/000114481
Conference Contribution - Poster Presentation (not in published proceedings)
Stevens, A., Appleby, S., & Kennedy, M. (2016, August-September). Many commercial hot-start polymerases demonstrate activity prior to thermal activation. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
2015
Conference Contribution - Poster Presentation (not in published proceedings)
Stevens, A., & Kennedy, M. (2015, August-September). CpG Methylation increases G-quadruplex re-association during PCR and influences genotyping of the imprinted MEST gene promoter. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Awarded Doctoral Degree
Stevens, A. J. (2015). The interaction of G-quadruplex DNA structure and cytosine methylation (PhD). University of Otago, Dunedin, New Zealand. Retrieved from http://hdl.handle.net/10523/6077
2014
Journal - Research Article
Stevens, A. J., Stuffrein-Roberts, S., Cree, S. L., Gibb, A., Miller, A. L., Doudney, K., Aitchison, A., Eccles, M. R., Joyce, P. R., … Kennedy, M. A. (2014). G-quadruplex structures and CpG methylation cause drop-out of the maternal allele in polymerase chain reaction amplification of the imprinted MEST gene promoter. PLoS ONE, 9(12), e113955. doi: 10.1371/journal.pone.0113955
2013
Conference Contribution - Published proceedings: Abstract
Stevens, A. J., Stuffrein-Roberts, S., Macmil, S., Gibb, A., Doudney, K., Miller, A. L., Bagshaw, A., Aitchison, A., Eccles, M. R., Joyce, P. R., … Kennedy, M. A. (2013). Allelic-dropout during PCR of the imprinted MEST promoter caused by interaction between G-quadruplex structures and DNA methylation. Proceedings of the 4th International Meeting on G-quadruplex Nucleic Acids: From Structure to Chemistry and Biology. 83. Retrieved from http://www.g4meeting2013.com/
2012
Conference Contribution - Poster Presentation (not in published proceedings)
Stevens, A., Stuffrein-Roberts, S., Miller, A., Gibb, A., Doudney, K., Bagshaw, A., Aitchison, A., Eccles, M., … Kennedy, M. (2012, August). G-quadruplex DNA structures, genomic imprinting and allelic drop-out in PCR. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Stevens, A. J., Stuffrein-Roberts, S., Miller, A. L., Gibb, A., Doudney, K., Bagshaw, A., Aitchison, A., Eccles, M. R., … Kennedy, M. A. (2012, August). G-quadruplex DNA structures, genomic imprinting and allelic drop-out in PCR. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
