Contact Details
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- Position
- PhD Student
- Qualifications
- MSc in Bioengineering
- Research summary
- The fabrication of surgical sutures for cutaneous wound healing
Research
Surgical sutures are implantable biomedical devices used for holding tissues together to achieve wound closure. Sutures are the most popular surgical implants in the global surgical equipment market. There are thousands of surgical operations using sutures to repair tissues every day. However, during surgical procedures, these sutures are susceptible to microbial adherence and bacteria may enter via the surgical site, which poses a high surgical site infection (SSI) rate. It may inhibit the wound healing process. In extreme cases, the SSIs may lead to life-threatening situations.
Right now, on the market, there is no ideal suture that can accomplish the necessary requirements such as excellent mechanical properties, infection inhibition, and inflammatory reduction. Therefore, an antimicrobial suture with good mechanical properties and that can enhance the wound healing process is highly desirable.
My research uses biopolymers loaded with natural compounds to produce bio-absorbable sutures for facilitating wound healing.
Publications
Rajabi, M., Deng, X., Ratnayake, J., & Gould, M. (2025). Keratin 3D printing: Sustainable biomaterials for regenerative medicine and biomanufacturing. Tissue Engineering Part A. Advance online publication. doi: 10.1177/19373341251398721 Journal - Research Article
Deng, X., Ratnayake, J., & Ali, A. (2025). Curcumin-loaded drug delivery systems for acute and chronic wound management: A review. Bioengineering, 12, 860. doi: 10.3390/bioengineering12080860 Journal - Research Other
Deng, X., Gould, M. L., Katare, R. G., & Ali, M. A. (2025). Antibacterial, antioxidant, and anti-inflammatory surgical sutures fabricated by melt mixing of a polymer blend with curcumin-loaded microspheres. Polymer Engineering & Science. Advance online publication. doi: 10.1002/pen.27159 Journal - Research Article
Deng, X. (2024). Drug-eluting biodegradable surgical suture for wound healing (PhD). University of Otago, Dunedin, New Zealand. Retrieved from https://hdl.handle.net/10523/42212 Awarded Doctoral Degree
Gould, M. L., Deng, X., Lyons, K., & Ali, A. (2024). In vivo and in vitro response to a regenerative dental scaffold. Materials, 17, 5384. doi: 10.3390/ma17215384 Journal - Research Article