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Professor Antony Braithwaite

Professor Antony BraithwaiteMSc, PhD

Professor Antony Braithwaite is head of the Cell Transformational Unit at the Children's Medical Research Institute, based at the University of Sydney. He splits his time between Otago and Sydney.

Antony completed his Bachelor and Masters of Science degrees at the University of Auckland before embarking on his PhD at the Australian National University. Antony was awarded a Howard Florey Fellowship and worked at the Marie Curie Cancer Research Institute in the UK, before returning to the Australian National University to lead a team studying basic mechanisms in cancer cell formation. In 1996, he took up a personal Professorship in Pathology at Otago.

Antony's research is focused on the regulation of cell proliferation and cell survival and the role played by the tumour suppressor protein, p53.

Publications

Wiles, A. K., Mehta, S., Millier, M., Woolley, A. G., Li, K., Parker, K., Kazantseva, M., Wilson, M., Young, K., Bowie, S., Ray, S., Slatter, T. L., Stamp, L. K., Hessian, P. A., & Braithwaite, A. W. (2023). Activated CD90/Thy-1 fibroblasts co-express the Δ133p53β isoform and are associated with highly inflamed rheumatoid arthritis. Arthritis Research & Therapy, 25, 62. doi: 10.1186/s13075-023-03040-8

Boix De Jesus, A. N., Taha, A., Wang, D., Mehta, P. M., Mehta, S., Reily-Bell, A., Polwatta Lekamlage, S., Machado Saraiva, A., Tahmeedzaman, T., … Royds, J., Braithwaite, A., Hung, N., & Slatter, T. L. (2023). Increased expression of the Δ133p53ß isoform enhances brain metastasis. International Journal of Molecular Sciences, 24, 1267. doi: 10.3390/ijms24021267

Reinhardt, L. S., Zhang, X., Groen, K., Morten, B. C., De Iuliis, G. N., Braithwaite, A. W., … Avery-Kiejda, K. A. (2022). Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage. Cell Death & Disease, 13, 907. doi: 10.1038/s41419-022-05349-9

Polwatta, S. N., Boix De Jesús, A. N., Wang, D., Taha, A., Kazantseva, M., Zhou, J., Mehta, S., Saraiva, A. M., … Royds, J., … Braithwaite, A. W., Hung, N. A., & Slatter, T. L. (2022, August). The Δ 133p53 isoform enhances cell-surface trafficking to promote metastasis. Verbal presentation at the Cancer Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.

Li, K., Ly, K., Mehta, S., & Braithwaite, A. (2022). Importance of crosstalk between the microbiota and the neuroimmune system for tissue homeostasis. Clinical & Translational Immunology, 11, e1394. doi: 10.1002/cti2.1394

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