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Postgraduate students in the Department of Pathology and Biomedical Science

Current students

PhD

Student Thesis title Supervisors
Bee Bathish Identification of novel peroxidase-catalysed sulfur cross-links in proteins Prof Christine Winterbourn, Prof Tony Kettle
Linda Buss Investigating exercise-mediated changes in the tumour microenvironment of melanoma and lung cancer A/Prof Gabi Dachs, A/Prof Margaret Currie, Dr Barry Hock, Prof Bridget Robinson
Leah Butt Measuring markers of immune response in patients treated with PD-1 inhibitors A/Prof Margaret Currie, Dr Barry Hock, Dr Elisabeth Phillips, Mr Jeremy Simcock, Dr Matthew Strother
Rebekah Crake Impact of obesity and inflammation on breast cancer cell response to chemotherapy A/Prof Margaret Currie, Dr Elisabeth Phillips, Prof Bridget Robinson
Dayang Datu Investigating the mechanisms of toxicity of ascorbate and its interaction with standard cancer therapies A/Prof Gabi Dachs, Prof Margreet Vissers
Piyush Jha Evaluating the therapeutic potential of hydrogen sulfide inhibition or administration in polymicrobial sepsis (PMS) Prof Madhav Bhatia, Prof Steve Chambers
Yusmiati Liau The application of nanopore sequencing technology for pharmacogenomics profiling in adverse drug reactions Prof Martin Kennedy, A/Prof John Pearson, A/Prof Matt Doogue
Ali Mohammadi Volatile organic compounds: identification and application as a diagnostic target for Legionnaires disease Prof Steve Chambers, Prof David Murdoch, Dr Amy Scott-Thomas
Arthur Morley-Bunker Scoping RNA biomarkers of colorectal cancer cases A/Prof Logan Walker, A/Prof Margaret Currie, A/Prof John Pearson, Mr Tim Eglinton
Stephanie Moran Promoting cell death in cancer cells Prof Mark Hampton, Prof Margreet Vissers
Citra Praditi Vitamin C and metastasis Prof Margreet Vissers, A/Prof Gabi Dachs
Annika Seddon Investigating the biology of tumour-associated neutrophils Prof Mark Hampton, Dr Margaret Currie, Prof Tony Kettle
Heather Shearer Sensitising pathogenic bacteria to neutrophil oxidants Prof Mark Hampton, Dr Heather Parker, Dr Paul Pace
Priyanka Sinha Genomic analysis of mood disorder drugs in bipolar disorder Prof Martin Kennedy, Dr Simone Cree, A/Prof John Pearson
Cassie Stylianou Copy variants and endometrial cancer risk A/Prof Logan Walker, A/Prof John Pearson
Kim Ton Application of new technologies to pharmacogenetics Prof Martin Kennedy, A/Prof John Pearson, A/Prof Matt Doogue
Eveline van Leeuwen Oxidative stress and redox regulation of the cytoskeleton Prof Mark Hampton, Prof Margreet Vissers
George Wiggins Gene expression variability in breast tumour development A/Prof Logan Walker, A/Prof John Pearson, A/Prof Mik Black
Jessika Wise 3D breast tumour models for drug discovery Dr Elisabeth Phillips, A/Prof Tim Woodfield, Dr Khoon Lim, A/Prof Margaret Currie
Masuma Zawari Bioavailability and health effects of isothiocynates from nutraceutical preparations Prof Mark Hampton, A/Prof Anitra Carr, Dr Dion Thompson

BBiomedSc(Hons)

Student Thesis titleSupervisor(s)
Krista DawsonCharacterising the relationship between Legionella longbeachae and their amoebal hosts: implications for Legionnaires’ disease preventionDr Sandy Slow, Prof Steve Chambers
Tess FeatherstonOxidative stress and antioxidant expression in human cancerProf Mark Hampton, Dr Martina Paumann-Page
Lorna ForresterMycobacterial resistance to killing by neutrophil oxidantsProf Mark Hampton, Dr Heather Parker
Jaya MontecilloGene-modification of breast cancer cells for cancer imagingA/Prof Gabi Dachs

2018

PhD

Student Thesis title Supervisors
Teagan Hoskin Oxidative post-translational modifications of calprotectin during inflammation Prof Tony Kettle, Dr Nina DickerhofProf Richard Gearry, Prof Andrew Day
Kate Vick Peroxiredoxin expression and redox state in human cancers Prof Mark Hampton, Prof Christine Winterbourn
Christina Wohlrab The role of ascorbate in controlling hypoxia factors in renal cell carcinoma  A/Prof Gabi Dachs, Dr Elisabeth Phillips, Prof Margreet Vissers, Prof Bridget Robinson

BBiomedSc(Hons)

Student Thesis title Supervisor(s)
Eleanor Burgess Can vitamin C reduce metastases in a mouse model of breast cancer? A/Prof Gabi Dachs
Isabelle Chai Copy number variants and familial breast and ovarian cancer risk A/Prof Logan Walker, Dr Vanessa Lattimore
Jessie Chang Targeted enrichment and Nanopore sequencing of RNA transcripts from breast cancer risk genes Prof Martin Kennedy, A/Prof Logan Walker, Dr Simone Cree, A/Prof John Pearson
Sarah Heath Intracellular redox changes during TNFα-mediated necroptosis  Prof Mark Hampton
James Swan Aspirin’s role in preventing E-cadherin cleavage by the carcinogenic Bacteroides fragilis toxin  A/Prof Jacqui Kennan, Prof Mark Hampton

2017

PhD

Student Thesis title Supervisors
Andrew Das The reactions of superoxide with tyrosyl radicals on proteins Prof Tony Kettle, Prof Christine Winterbourn
Ravinder Reddy Gaddam The role of hydrogen sulfide, substance P and Kupffer cells on inflammation and liver sinusoidal endothelial cells in sepsis Prof Madhav Bhatia, Prof Steve Chambers
Hannah Kennedy Application of emerging sequencing and genomic technologies to diagnostic molecular genetics Prof Peter George, Dr Kit Doudney
Vanessa Lattimore Genetic variation and mRNA splicing in familial breast cancer genes A/Prof Logan Walker, A/Prof Margaret Currie, Prof Bridget Robinson, A/Prof John Pearson
Emma Spencer Exploring the anti-cancer and anti-inflammatory properties of isothiocyanates Prof Mark Hampton, Prof Tony Kettle

BBiomedSc(Hons)

Student Thesis title Supervisor
Leah Butt Measuring markers of immune response in patients treated with Nivolumab (Opdivo) or Pembrolizumab (Keytruda) A/Prof Margaret Currie

2016

PhD

Student Thesis title Supervisors
Abel Ang Role of endogenous hydrogen sulfide synthesised by cystathionine-gamma-lyase in the inflammatory response in acute pancreatitis Prof Madhav Bhatia, Dr Greg Giles
Sarah Appleby Telomere length as a putative biomarker of health and disease Prof Martin Kennedy, Prof Mark Hampton, A/Prof John Pearson
Alireza Badiei Effect of cystathionine-gamma-lyase gene silencing with siRNA on inflammation in acute pancreatitis Prof Madhav Bhatia, Prof Steve Chambers
Janice Chew-Harris Biomarkers of kidney function; Validity of estimates in clinical practice A/Prof Chris Florkowski, Prof Peter George
Aaron Stevens The interaction of G-Quadruplex DNA structure and cytosine methylation Prof Martin Kennedy, Dr Simone Cree

BBiomedSc(Hons)

Student Thesis title Supervisors
Rosie Burn A validation study to detect markers of proliferation adequacy in the endometrium Prof Martin Kennedy, Dr Gloria Evans, Prof John Evans
Linda Buss The influence of exercise and hyperlipidaemia on breast cancer A/Prof Gabi Dachs, Prof Margreet Vissers 
Lucy de Jong Diagnostic applications of a Nanopore sequencing device Prof Martin Kennedy
Tara Swadi A novel strategy to prevent bacterial biofilm formation using methylthioadenosine-nucleosidase inhibitors Prof Steve Chambers

2015

PhD

Student Thesis title Supervisors
Diana Balasubramanain Gene expression changes induced by mood stabilizer drugs in a serotonergic cell line Prof Martin Kennedy, Prof Peter Joyce, Prof Mark Hampton
Simone Bayer Redox State Of Erythrocyte Peroxiredoxin 2 During Oxidative Stress And Its Effect On Membrane Binding Prof Christine Winterbourn, Prof Mark Hampton
Lizzie Campbell Regulation of Hypoxia-Inducible Factor-Mediated Tumour Growth by Ascorbate A/Prof Gabi Dachs, Prof Bridget Robinson, Prof Margreet Vissers
Eng Wee Chua Understanding Adverse Drug Reactions Using Genomic Sequencing Prof Martin Kennedy, Dr Ruth Savage
Tony Rahman Venous thromboembolism in patients with cancer undertaking chemotherapy Prof Bridget Robinson, A/Prof Margaret Currie, Dr Mark Smith
Usha Rani Talla (Pujary) The Effect of Hypoxia on Neutrophil Survival and Function Prof Margreet Vissers, Prof Mark Hampton, Dr Heather Parker

BBiomedSc(Hons)

Student Thesis title Supervisors
Mark Brinsden Measuring Mitochondrial Dysfunction in Humans Dr Andree Pearson, Prof Mark Hampton
Rebekah Crake Exploring Molecular Links between Obesity and Breast Cancer A/Prof Logan Walker, A/Prof Margaret Currie, Dr Elisabeth Phillips
Sarah Drake Investigating the pro-apoptotic properties of portimine Prof Mark Hampton
Melanie Hamzah Inactivation of a Thiol-Dependent Enzyme by Urate Hydroperoxide Prof Tony Kettle, Prof Mark Hampton
Morgan Jones Does fat provide energy for breast tumour cell invasion and metastasis? A/Prof Margaret Currie, Dr Elisabeth Phillips, Prof Mark Hampton
Anishah Mandani Development of a metabolic syndrome mouse model of breast cancer A/Prof Gabi Dachs, A/Prof Margaret Currie, Dr Elisabeth Phillips
Millie Taylor Impact of G-quadruplex structures and DNA methylation on allelic drop-out during in vitro amplification of imprinted genes Prof Martin Kennedy, Dr Simone Cree

2014

PhD

Student Thesis title Supervisors
James Falvey Macrophage Migration Inhibitory Factor and Inflammatory Bowel Disease Prof Richard Gearry, Prof Mark Hampton, Dr Rebecca Roberts
Rebecca Poynton Peroxiredoxin 3 and oxidative stress in mitochondria Prof Mark Hampton, Prof Christine Winterbourn, Dr Andrea Betz

BBiomedSc(Hons)

Student Thesis Title Supervisor
Bee Bathish The effect of cell metabolism on epigenetic processes in cancer cells Prof Margreet Vissers
Masuma Zawari Involvement of mitochondria and peroxiredoxin in TNF-mediated necroptosis Prof Mark Hampton

2013

PhD

Student Thesis title Supervisors
Caroline Kuiper* The role of ascorbate in the regulation of HIF-1 in cancer cells Prof Margreet Vissers, A/Prof Gabi Dachs, A/Prof Margaret Currie
Nick Magon Oxidative Modification of Calprotectin During Inflammation: Development as a Biomarker Prof Mark Hampton, Prof Tony Kettle, Prof Richard Gearry
Anja Werno Development of improved diagnostic testing methods for invasive pneumococcal disease Prof David Murdoch, Prof Peter George

*Divisional Exceptional Thesis

BBiomedSc(Hons)

Student Thesis title Supervisors
Teresa Flett Gene transfer to restore vitamin C synthesis in human cell line A/Prof Gabi Dachs, Prof Margreet Vissers
Zac Gerring Evaluating molecular markers of breast tumour progression A/Prof Logan Walker, Dr Gavin Harris
Annika Seddon Immune suppression and squamous cell carcinoma tumour biology A/Prof Margaret Currie
Kate Vick Functional consequences of lowering mitochondrial peroxiredoxin 3 expression Prof Mark Hampton

2012

PhD

Student Thesis title Supervisors
Shrawan Bhandari Investigation of the biosynthesis of 2-Pentylfuran from 'Aspergillus fumigatus in vitro' and 'in vivo' Prof Steve Chambers, Dr Amy Scott-Thomas, Prof Chris Charles, Dr Richard Weld

2011

PhD

Student Thesis title Supervisors
Melanie Coker* The role of reactive chlorine species in bacterial killing by neutrophils Prof Tony Kettle, Prof Christine Winterbourn
Sarah Deng Gene regulation by antidepressant drugs Prof Martin Kennedy, Prof Peter Joyce
Alice Johnstone Implications for drug addiction development from expressional analyses of rattus norvegicus striatal
tissue following methamphetamine and benzylpiperazine exposure
Prof Martin Kennedy
Vikas Kumar Oxidative changes in cardiac proteome during ischemia/reperfusion Prof Christine Winterbourn, Prof Mark Hampton
Amy (Marshall) Osborne* Assessment of genetic variation in the threatened New Zealand sea lion, Phocarctos hookeri, and its association with fitness Prof Neil Gemmell, Prof Martin Kennedy
Katya Volkova Tumour angiogenesis : the role of metabolic syndrome and insulin resistence A/Prof Margaret Currie, A/Prof Gabi DachsProf Bridget Robinson

* Divisional Exceptional Thesis

BBiomedSc(Hons)

Student Thesis title Supervisors
Lizzie Campbell Hydrogen Sulfide: Investigation into the Effects of Different H2S Donors on the Upregulation of Inflammatory Cytokines Prof Madhav Bhatia
Teagan Hoskin Neutrophil Activation in Inflammatory Bowel Disease Prof Richard Gearry, Prof Tony Kettle
Sarah Jodczyk (Appleby) Establishment and validation of a telomere length assay Prof Martin Kennedy
Emma Spencer Inhibiting the pro-inflammatory cytokine MIF Prof Mark Hampton

2010

PhD

Student Thesis title Supervisors
Ryan Davis* The molecular basis of fibrinogen disease: Structure, function and pathology Prof Stephen Brennan, Prof Peter George
Michelle Hunt Vessel-directed enzyme-prodrug therapy for cancer A/Prof Gabi Dachs, A/Prof Margaret CurrieProf Bridget Robinson
Kasia Mackenzie Why are skin cancers more aggressive in renal transplant recipients? A/Prof Margaret Currie, Dr Barry HockProf Bridget RobinsonA/Prof Gabi Dachs, Dr Andrew Miller, Prof Justin Roake, Mr Jeremy Simcock
Karina O'Connor The effect of oxidative stress on DNA methylation Prof Mark Hampton, Prof Christine Winterbourn, Prof Anthony Reeve
Melissa Stacey Cell antioxidant pathways for disposal of MPO-derived oxidants Prof Christine Winterbourn, Prof Margreet Vissers

* Divisional Exceptional Thesis

BBiomedSc(Hons)

Student Thesis title Supervisor
Andrew Gibb Does promoter variation in the USP46 gene influence antidepressant response? Prof Martin Kennedy
Min-Hi Han Assessing a blood biomarker of lung infection Prof Christine Winterbourn
Aaron Hayes Detecting 2-aminoacetophenone and pyocyanin from clinical strains of Pseudomonas aeruginosa Dr Amy Scott-Thomas
Hannah Kennedy Development of an assay for interferon beta bioavailability in relapsing-remitting MS patients Prof Stephen Brennan
Tamas Major Evaluation of The Four-and-a-half LIM 2 (FHL2) Single Polypeptide As A Potential Biomarker of Cardio-Renal Syndrome (CRS) A/Prof Chris Pemberton
Anna van Pomeren Myeloid-Derived Suppressor Cells, Tumour Angiogenesis, and Cancer Progression A/Prof Margaret Currie

2009

PhD

Student Thesis title Supervisors
Michael Bland Genetic and functional analysis of novel serotonergic candidate genes in psychiatric disorders Prof Martin Kennedy,  Prof Peter Joyce, Dr Rebecca Roberts
Kristin Brown* Cellular targets of isothiocyanates Prof Mark Hampton, Prof Christine Winterbourn, Dr Sarah Cuddihy
Andy Cox* Peroxiredoxin 3 and the regulation of mitochondrial hydrogen peroxide Prof Mark Hampton, Prof Christine Winterbourn, Dr Sarah Cuddihy
Dylan Glubb Pharmacogenomics of the antidepressant Paroxetine Prof Martin Kennedy, Prof Peter Joyce
Jessie Green* Oxidant production inside the phagosomes of neutrophils Prof Christine Winterbourn, Prof Tony Kettle, Prof Mark Hampton

* Divisional Exceptional Thesis

2008

PhD

Student Thesis title Supervisors
Sarah Gunningham The role of vascular endothelial growth factors and their receptors in breast and colorectal tumour angiogenesis A/Prof Margaret Currie, Prof Vicky Cameron, Prof Bridget Robinson, Prof Stephen Fox
Tim Harwood Glutathione sulfonamide as a biomarker of oxidative stress during inflammation Prof Christine Winterbourn, Prof Tony Kettle
Felicia Low The antioxidant activity of erythrocyte peroxiredoxin 2 and its role in protecting haemoglobin Prof Christine Winterbourn, Prof Mark Hampton
So-Young Moon Identification of genetic aberrations in chronic lymphocytic leukaemia using array CGH A/Prof Margaret Currie, Dr Peter Ganly, A/Prof Christine Morris
Campbell Sheen Molecular characterisation of coagulation disorders Prof Stephen Brennan, A/Prof Christine Morris, Dr Mark Smith
Selma Stuffrein-Roberts Allelic expression patterns in psychiatric candidate genes Prof Martin Kennedy, Prof Vicky Cameron, Dr Michael Eccles
Rachel Wilkie Oxidative stress and apoptosis in the phagocytic neutrophils Prof Mark Hampton, Prof Margreet Vissers

2007

PhD

Student Thesis title Supervisors
Mathew Littlejohn Pharmacogenetics of the B2 adrenergic receptor and related molecules Prof Martin Kennedy, Prof Tony Kettle,
Robyn Midwinter The role of chloramines on the inflammatory process in endothelial cells Prof Christine WinterbournProf Margreet Vissers,
Logan Walker Genetic aberrations in breast cancer Prof Bridget Robinson, A/Prof Christine Morris

2006

PhD

Student Thesis title Supervisors
Amy Dear Assembly and secretion of Fibrinogen: Evidence from human mutation Prof Stephen Brennan, Prof Peter George
Patrick McHugh A cellular model for investigating antidepressant pharmacogenomics Prof Martin Kennedy, Prof Peter Joyce, Dr Geraldine Rogers
Jennifer Scotter The laboratory diagnosis of invasive aspergillosis Prof Stephen Chambers, Dr Peter Ganly, Prof David Murdoch
Malina Storer Development of laboratory tests for assessing vitamin status Prof Stephen Chambers, Dr Michael Lever

2005

PhD

Student Thesis title Supervisors
Vickie Hanrahan The role of homeobox gene HLX1 in haematopoiesis and leukaemia Prof Martin Kennedy, Prof Stephen Brennan, Dr Geraldine Rogers

2004

PhD

Student Thesis title Supervisors
James Baty Hydrogen peroxide-sensitive thiol proteins: Potential targets in redox signalling Prof Christine Winterbourn, Prof Mark Hampton,
Warwick Dellow Glycine Betaine and Diabetes Mellitus Prof Stephen Chambers, Prof Peter George, Dr Michael Lever
Ghassan Maghzal The effects of genes and the environment on the structure and function of fibrinogen Prof Stephen Brennan, Prof Peter George

2003

PhD

Student Thesis title Supervisors
Fook Choe Cheah Lung inflammation and oxidative injury in hyaline membrane disease: The role of NF-kB activation in pulmonary leukocytes Prof Christine Winterbourn, Prof Brian Darlow
Sheryl Gough Molecular analysis of a novel chromosome translocation associated with acute lymphoid leukemia Dr Peter Ganly, A/Prof Christine Morris
Harold Neal CRESCENTIC GLOMERULONEPHRITIS: Associations of Eosinophils and Transforming Growth Factors Emeritus Prof Robin Fraser

2002

PhD

Student Thesis title Supervisors
Suzanne Benjes BCR-ABL1 Recombination Mechanisms in Chronic Myeloid Leukaemia: Clues from Complexity Prof Vicky Cameron, A/Prof Christine Morris
Sangeeta Budhia Isolation and Characterisation of Novel Human Dendritic Cell-Associated Molecule, DD1.1 Dr Barry Hock, Prof Martin Kennedy, Prof Justin Roake
Anna Chapman Aggregation and chlorination of proteins by hypochlorous acid: Insights into reactions within neutrophils Prof Tony Kettle, Porf Christine Winterbourn
Victoria Metcalf The Molecular Evolution of Serum Albumin in Non-Mammalian Vertebrate Species Prof Stephen Brennan, Prof Peter George