Postgraduate students in the Department of Pathology and Biomedical Science

Current students

PhD

Student	Thesis title	Supervisors
Bee Bathish	Identification of novel peroxidase-catalysed sulfur cross-links in proteins	Prof Christine Winterbourn, Prof Tony Kettle
Linda Buss	Investigating exercise-mediated changes in the tumour microenvironment of melanoma and lung cancer	A/Prof Gabi Dachs, A/Prof Margaret Currie, Dr Barry Hock, Prof Bridget Robinson
Leah Butt	Measuring markers of immune response in patients treated with PD-1 inhibitors	A/Prof Margaret Currie, Dr Barry Hock, Dr Elisabeth Phillips, Mr Jeremy Simcock, Dr Matthew Strother
Rebekah Crake	Impact of obesity and inflammation on breast cancer cell response to chemotherapy	A/Prof Margaret Currie, Dr Elisabeth Phillips, Prof Bridget Robinson
Dayang Datu	Investigating the mechanisms of toxicity of ascorbate and its interaction with standard cancer therapies	A/Prof Gabi Dachs, Prof Margreet Vissers
Piyush Jha	Evaluating the therapeutic potential of hydrogen sulfide inhibition or administration in polymicrobial sepsis (PMS)	Prof Madhav Bhatia, Prof Steve Chambers
Jaslyn Kee	The application of pharmacogenetics to understanding adverse drug reactions	Prof Martin Kennedy, Dr Simran Maggo
Yusmiati Liau	The application of nanopore sequencing technology for pharmacogenomics profiling in adverse drug reactions	Prof Martin Kennedy, A/Prof John Pearson, A/Prof Matt Doogue
Ali Mohammadi	Volatile organic compounds: identification and application as a diagnostic target for Legionnaires disease	Prof Steve Chambers, Prof David Murdoch, Dr Amy Scott-Thomas
Stephanie Moran	Promoting cell death in cancer cells	Prof Mark Hampton, Prof Margreet Vissers
Arthur Morley-Bunker	Scoping RNA biomarkers of colorectal cancer cases	A/Prof Logan Walker, A/Prof Margaret Currie, A/Prof John Pearson, Mr Tim Eglinton
Hadley Northcott	Allele-specific expression analysis of BRCA1/2 variants in breast cancer patients.	A/Prof Logan Walker, Dr Vanessa Lattimore
Citra Praditi	Vitamin C and metastasis	Prof Margreet Vissers, A/Prof Gabi Dachs
Annika Seddon	Investigating the biology of tumour-associated neutrophils	Prof Mark Hampton, Dr Margaret Currie, Prof Tony Kettle
Heather Shearer	Sensitising pathogenic bacteria to neutrophil oxidants	Prof Mark Hampton, Dr Heather Parker, Dr Paul Pace
Priyanka Sinha	Genomic analysis of mood disorder drugs in bipolar disorder	Prof Martin Kennedy, Dr Simone Cree, A/Prof John Pearson
Cassie Stylianou	Copy variants and endometrial cancer risk	A/Prof Logan Walker, A/Prof John Pearson
Kim Ton	Application of new technologies to pharmacogenetics	Prof Martin Kennedy, A/Prof John Pearson, A/Prof Matt Doogue
Eveline van Leeuwen	Oxidative stress and redox regulation of the cytoskeleton	Prof Mark Hampton, Prof Margreet Vissers
George Wiggins	Gene expression variability in breast tumour development	A/Prof Logan Walker, A/Prof John Pearson, A/Prof Mik Black
Jessika Wise	3D breast tumour models for drug discovery	Dr Elisabeth Phillips, A/Prof Tim Woodfield, Dr Khoon Lim, A/Prof Margaret Currie

BBiomedSc(Hons)

Student	Thesis title	Supervisor(s)
Krista Dawson	Characterising the relationship between Legionella longbeachae and their amoebal hosts: implications for Legionnaires’ disease prevention	Dr Sandy Slow, Prof Steve Chambers
Tess Featherston	Oxidative stress and antioxidant expression in human cancer	Prof Mark Hampton, Dr Martina Paumann-Page
Lorna Forrester	Mycobacterial resistance to killing by neutrophil oxidants	Prof Mark Hampton, Dr Heather Parker
Jaya Montecillo	Gene-modification of breast cancer cells for cancer imaging	A/Prof Gabi Dachs

2019

Student	Thesis title	Supervisors
Masuma Zawari	Bioavailability and biological effects of isothiocyanates from broccoli sprout powder	Prof Mark Hampton, A/Prof Anitra Carr, Dr Dion Thompson

2018

PhD

Student	Thesis title	Supervisors
Teagan Hoskin	Oxidative post-translational modifications of calprotectin during inflammation	Prof Tony Kettle, Dr Nina Dickerhof, Prof Richard Gearry, Prof Andrew Day
Kate Vick	Peroxiredoxin expression and redox state in human cancers	Prof Mark Hampton, Prof Christine Winterbourn
Christina Wohlrab	The role of ascorbate in controlling hypoxia factors in renal cell carcinoma 	A/Prof Gabi Dachs, Dr Elisabeth Phillips, Prof Margreet Vissers, Prof Bridget Robinson

BBiomedSc(Hons)

Student	Thesis title	Supervisor(s)
Eleanor Burgess	Can vitamin C reduce metastases in a mouse model of breast cancer?	A/Prof Gabi Dachs
Isabelle Chai	Copy number variants and familial breast and ovarian cancer risk	A/Prof Logan Walker, Dr Vanessa Lattimore
Jessie Chang	Targeted enrichment and Nanopore sequencing of RNA transcripts from breast cancer risk genes	Prof Martin Kennedy, A/Prof Logan Walker, Dr Simone Cree, A/Prof John Pearson
Sarah Heath	Intracellular redox changes during TNFα-mediated necroptosis 	Prof Mark Hampton
James Swan	Aspirin’s role in preventing E-cadherin cleavage by the carcinogenic Bacteroides fragilis toxin 	A/Prof Jacqui Kennan, Prof Mark Hampton

2017

PhD

Student	Thesis title	Supervisors
Andrew Das	The reactions of superoxide with tyrosyl radicals on proteins	Prof Tony Kettle, Prof Christine Winterbourn
Ravinder Reddy Gaddam	The role of hydrogen sulfide, substance P and Kupffer cells on inflammation and liver sinusoidal endothelial cells in sepsis	Prof Madhav Bhatia, Prof Steve Chambers
Hannah Kennedy	Application of emerging sequencing and genomic technologies to diagnostic molecular genetics	Prof Peter George, Dr Kit Doudney
Vanessa Lattimore	Genetic variation and mRNA splicing in familial breast cancer genes	A/Prof Logan Walker, A/Prof Margaret Currie, Prof Bridget Robinson, A/Prof John Pearson
Emma Spencer	Exploring the anti-cancer and anti-inflammatory properties of isothiocyanates	Prof Mark Hampton, Prof Tony Kettle

BBiomedSc(Hons)

Student	Thesis title	Supervisor
Leah Butt	Measuring markers of immune response in patients treated with Nivolumab (Opdivo) or Pembrolizumab (Keytruda)	A/Prof Margaret Currie

2016

PhD

Student	Thesis title	Supervisors
Abel Ang	Role of endogenous hydrogen sulfide synthesised by cystathionine-gamma-lyase in the inflammatory response in acute pancreatitis	Prof Madhav Bhatia, Dr Greg Giles
Sarah Appleby	Telomere length as a putative biomarker of health and disease	Prof Martin Kennedy, Prof Mark Hampton, A/Prof John Pearson
Alireza Badiei	Effect of cystathionine-gamma-lyase gene silencing with siRNA on inflammation in acute pancreatitis	Prof Madhav Bhatia, Prof Steve Chambers
Janice Chew-Harris	Biomarkers of kidney function; Validity of estimates in clinical practice	A/Prof Chris Florkowski, Prof Peter George
Aaron Stevens	The interaction of G-Quadruplex DNA structure and cytosine methylation	Prof Martin Kennedy, Dr Simone Cree

BBiomedSc(Hons)

Student	Thesis title	Supervisors
Rosie Burn	A validation study to detect markers of proliferation adequacy in the endometrium	Prof Martin Kennedy, Dr Gloria Evans, Prof John Evans
Linda Buss	The influence of exercise and hyperlipidaemia on breast cancer	A/Prof Gabi Dachs, Prof Margreet Vissers
Lucy de Jong	Diagnostic applications of a Nanopore sequencing device	Prof Martin Kennedy
Tara Swadi	A novel strategy to prevent bacterial biofilm formation using methylthioadenosine-nucleosidase inhibitors	Prof Steve Chambers

2015

PhD

Student	Thesis title	Supervisors
Diana Balasubramanain	Gene expression changes induced by mood stabilizer drugs in a serotonergic cell line	Prof Martin Kennedy, Prof Peter Joyce, Prof Mark Hampton
Simone Bayer	Redox State Of Erythrocyte Peroxiredoxin 2 During Oxidative Stress And Its Effect On Membrane Binding	Prof Christine Winterbourn, Prof Mark Hampton
Lizzie Campbell	Regulation of Hypoxia-Inducible Factor-Mediated Tumour Growth by Ascorbate	A/Prof Gabi Dachs, Prof Bridget Robinson, Prof Margreet Vissers
Eng Wee Chua	Understanding Adverse Drug Reactions Using Genomic Sequencing	Prof Martin Kennedy, Dr Ruth Savage
Tony Rahman	Venous thromboembolism in patients with cancer undertaking chemotherapy	Prof Bridget Robinson, A/Prof Margaret Currie, Dr Mark Smith
Usha Rani Talla (Pujary)	The Effect of Hypoxia on Neutrophil Survival and Function	Prof Margreet Vissers, Prof Mark Hampton, Dr Heather Parker

BBiomedSc(Hons)

Student	Thesis title	Supervisors
Mark Brinsden	Measuring Mitochondrial Dysfunction in Humans	Dr Andree Pearson, Prof Mark Hampton
Rebekah Crake	Exploring Molecular Links between Obesity and Breast Cancer	A/Prof Logan Walker, A/Prof Margaret Currie, Dr Elisabeth Phillips
Sarah Drake	Investigating the pro-apoptotic properties of portimine	Prof Mark Hampton
Melanie Hamzah	Inactivation of a Thiol-Dependent Enzyme by Urate Hydroperoxide	Prof Tony Kettle, Prof Mark Hampton
Morgan Jones	Does fat provide energy for breast tumour cell invasion and metastasis?	A/Prof Margaret Currie, Dr Elisabeth Phillips, Prof Mark Hampton
Anishah Mandani	Development of a metabolic syndrome mouse model of breast cancer	A/Prof Gabi Dachs, A/Prof Margaret Currie, Dr Elisabeth Phillips
Millie Taylor	Impact of G-quadruplex structures and DNA methylation on allelic drop-out during in vitro amplification of imprinted genes	Prof Martin Kennedy, Dr Simone Cree

2014

PhD

Student	Thesis title	Supervisors
James Falvey	Macrophage Migration Inhibitory Factor and Inflammatory Bowel Disease	Prof Richard Gearry, Prof Mark Hampton, Dr Rebecca Roberts
Rebecca Poynton	Peroxiredoxin 3 and oxidative stress in mitochondria	Prof Mark Hampton, Prof Christine Winterbourn, Dr Andrea Betz

BBiomedSc(Hons)

Student	Thesis Title	Supervisor
Bee Bathish	The effect of cell metabolism on epigenetic processes in cancer cells	Prof Margreet Vissers
Masuma Zawari	Involvement of mitochondria and peroxiredoxin in TNF-mediated necroptosis	Prof Mark Hampton

2013

PhD

Student	Thesis title	Supervisors
Caroline Kuiper*	The role of ascorbate in the regulation of HIF-1 in cancer cells	Prof Margreet Vissers, A/Prof Gabi Dachs, A/Prof Margaret Currie
Nick Magon	Oxidative Modification of Calprotectin During Inflammation: Development as a Biomarker	Prof Mark Hampton, Prof Tony Kettle, Prof Richard Gearry
Anja Werno	Development of improved diagnostic testing methods for invasive pneumococcal disease	Prof David Murdoch, Prof Peter George

*Divisional Exceptional Thesis

BBiomedSc(Hons)

Student	Thesis title	Supervisors
Teresa Flett	Gene transfer to restore vitamin C synthesis in human cell line	A/Prof Gabi Dachs, Prof Margreet Vissers
Zac Gerring	Evaluating molecular markers of breast tumour progression	A/Prof Logan Walker, Dr Gavin Harris
Annika Seddon	Immune suppression and squamous cell carcinoma tumour biology	A/Prof Margaret Currie
Kate Vick	Functional consequences of lowering mitochondrial peroxiredoxin 3 expression	Prof Mark Hampton

2012

PhD

Student	Thesis title	Supervisors
Shrawan Bhandari	Investigation of the biosynthesis of 2-Pentylfuran from 'Aspergillus fumigatus in vitro' and 'in vivo'	Prof Steve Chambers, Dr Amy Scott-Thomas, Prof Chris Charles, Dr Richard Weld

2011

PhD

Student	Thesis title	Supervisors
Melanie Coker*	The role of reactive chlorine species in bacterial killing by neutrophils	Prof Tony Kettle, Prof Christine Winterbourn
Sarah Deng	Gene regulation by antidepressant drugs	Prof Martin Kennedy, Prof Peter Joyce
Alice Johnstone	Implications for drug addiction development from expressional analyses of rattus norvegicus striatal tissue following methamphetamine and benzylpiperazine exposure	Prof Martin Kennedy
Vikas Kumar	Oxidative changes in cardiac proteome during ischemia/reperfusion	Prof Christine Winterbourn, Prof Mark Hampton
Amy (Marshall) Osborne*	Assessment of genetic variation in the threatened New Zealand sea lion, Phocarctos hookeri, and its association with fitness	Prof Neil Gemmell, Prof Martin Kennedy
Katya Volkova	Tumour angiogenesis : the role of metabolic syndrome and insulin resistence	A/Prof Margaret Currie, A/Prof Gabi Dachs, Prof Bridget Robinson

* Divisional Exceptional Thesis

BBiomedSc(Hons)

Student	Thesis title	Supervisors
Lizzie Campbell	Hydrogen Sulfide: Investigation into the Effects of Different H2S Donors on the Upregulation of Inflammatory Cytokines	Prof Madhav Bhatia
Teagan Hoskin	Neutrophil Activation in Inflammatory Bowel Disease	Prof Richard Gearry, Prof Tony Kettle
Sarah Jodczyk (Appleby)	Establishment and validation of a telomere length assay	Prof Martin Kennedy
Emma Spencer	Inhibiting the pro-inflammatory cytokine MIF	Prof Mark Hampton

2010

PhD

Student	Thesis title	Supervisors
Ryan Davis*	The molecular basis of fibrinogen disease: Structure, function and pathology	Prof Stephen Brennan, Prof Peter George
Michelle Hunt	Vessel-directed enzyme-prodrug therapy for cancer	A/Prof Gabi Dachs, A/Prof Margaret Currie, Prof Bridget Robinson
Kasia Mackenzie	Why are skin cancers more aggressive in renal transplant recipients?	A/Prof Margaret Currie, Dr Barry Hock, Prof Bridget Robinson,  A/Prof Gabi Dachs, Dr Andrew Miller, Prof Justin Roake, Mr Jeremy Simcock
Karina O'Connor	The effect of oxidative stress on DNA methylation	Prof Mark Hampton, Prof Christine Winterbourn, Prof Anthony Reeve
Melissa Stacey	Cell antioxidant pathways for disposal of MPO-derived oxidants	Prof Christine Winterbourn, Prof Margreet Vissers

* Divisional Exceptional Thesis

BBiomedSc(Hons)

Student	Thesis title	Supervisor
Andrew Gibb	Does promoter variation in the USP46 gene influence antidepressant response?	Prof Martin Kennedy
Min-Hi Han	Assessing a blood biomarker of lung infection	Prof Christine Winterbourn
Aaron Hayes	Detecting 2-aminoacetophenone and pyocyanin from clinical strains of Pseudomonas aeruginosa	Dr Amy Scott-Thomas
Hannah Kennedy	Development of an assay for interferon beta bioavailability in relapsing-remitting MS patients	Prof Stephen Brennan
Tamas Major	Evaluation of The Four-and-a-half LIM 2 (FHL2) Single Polypeptide As A Potential Biomarker of Cardio-Renal Syndrome (CRS)	A/Prof Chris Pemberton
Anna van Pomeren	Myeloid-Derived Suppressor Cells, Tumour Angiogenesis, and Cancer Progression	A/Prof Margaret Currie

2009

PhD

Student	Thesis title	Supervisors
Michael Bland	Genetic and functional analysis of novel serotonergic candidate genes in psychiatric disorders	Prof Martin Kennedy,  Prof Peter Joyce, Dr Rebecca Roberts
Kristin Brown*	Cellular targets of isothiocyanates	Prof Mark Hampton, Prof Christine Winterbourn, Dr Sarah Cuddihy
Andy Cox*	Peroxiredoxin 3 and the regulation of mitochondrial hydrogen peroxide	Prof Mark Hampton, Prof Christine Winterbourn, Dr Sarah Cuddihy
Dylan Glubb	Pharmacogenomics of the antidepressant Paroxetine	Prof Martin Kennedy, Prof Peter Joyce
Jessie Green*	Oxidant production inside the phagosomes of neutrophils	Prof Christine Winterbourn, Prof Tony Kettle, Prof Mark Hampton

* Divisional Exceptional Thesis

2008

PhD

Student	Thesis title	Supervisors
Sarah Gunningham	The role of vascular endothelial growth factors and their receptors in breast and colorectal tumour angiogenesis	A/Prof Margaret Currie, Prof Vicky Cameron, Prof Bridget Robinson, Prof Stephen Fox
Tim Harwood	Glutathione sulfonamide as a biomarker of oxidative stress during inflammation	Prof Christine Winterbourn, Prof Tony Kettle
Felicia Low	The antioxidant activity of erythrocyte peroxiredoxin 2 and its role in protecting haemoglobin	Prof Christine Winterbourn, Prof Mark Hampton
So-Young Moon	Identification of genetic aberrations in chronic lymphocytic leukaemia using array CGH	A/Prof Margaret Currie, Dr Peter Ganly, A/Prof Christine Morris
Campbell Sheen	Molecular characterisation of coagulation disorders	Prof Stephen Brennan, A/Prof Christine Morris, Dr Mark Smith
Selma Stuffrein-Roberts	Allelic expression patterns in psychiatric candidate genes	Prof Martin Kennedy, Prof Vicky Cameron, Dr Michael Eccles
Rachel Wilkie	Oxidative stress and apoptosis in the phagocytic neutrophils	Prof Mark Hampton, Prof Margreet Vissers

2007

PhD

Student	Thesis title	Supervisors
Mathew Littlejohn	Pharmacogenetics of the B2 adrenergic receptor and related molecules	Prof Martin Kennedy, Prof Tony Kettle,
Robyn Midwinter	The role of chloramines on the inflammatory process in endothelial cells	Prof Christine Winterbourn, Prof Margreet Vissers,
Logan Walker	Genetic aberrations in breast cancer	Prof Bridget Robinson, A/Prof Christine Morris

2006

PhD

Student	Thesis title	Supervisors
Amy Dear	Assembly and secretion of Fibrinogen: Evidence from human mutation	Prof Stephen Brennan, Prof Peter George
Patrick McHugh	A cellular model for investigating antidepressant pharmacogenomics	Prof Martin Kennedy, Prof Peter Joyce, Dr Geraldine Rogers
Jennifer Scotter	The laboratory diagnosis of invasive aspergillosis	Prof Stephen Chambers, Dr Peter Ganly, Prof David Murdoch
Malina Storer	Development of laboratory tests for assessing vitamin status	Prof Stephen Chambers, Dr Michael Lever

2005

PhD

Student	Thesis title	Supervisors
Vickie Hanrahan	The role of homeobox gene HLX1 in haematopoiesis and leukaemia	Prof Martin Kennedy, Prof Stephen Brennan, Dr Geraldine Rogers

2004

PhD

Student	Thesis title	Supervisors
James Baty	Hydrogen peroxide-sensitive thiol proteins: Potential targets in redox signalling	Prof Christine Winterbourn, Prof Mark Hampton,
Warwick Dellow	Glycine Betaine and Diabetes Mellitus	Prof Stephen Chambers, Prof Peter George, Dr Michael Lever
Ghassan Maghzal	The effects of genes and the environment on the structure and function of fibrinogen	Prof Stephen Brennan, Prof Peter George

2003

PhD

Student	Thesis title	Supervisors
Fook Choe Cheah	Lung inflammation and oxidative injury in hyaline membrane disease: The role of NF-kB activation in pulmonary leukocytes	Prof Christine Winterbourn, Prof Brian Darlow
Sheryl Gough	Molecular analysis of a novel chromosome translocation associated with acute lymphoid leukemia	Dr Peter Ganly, A/Prof Christine Morris
Harold Neal	CRESCENTIC GLOMERULONEPHRITIS: Associations of Eosinophils and Transforming Growth Factors	Emeritus Prof Robin Fraser

2002

PhD

Student	Thesis title	Supervisors
Suzanne Benjes	BCR-ABL1 Recombination Mechanisms in Chronic Myeloid Leukaemia: Clues from Complexity	Prof Vicky Cameron, A/Prof Christine Morris
Sangeeta Budhia	Isolation and Characterisation of Novel Human Dendritic Cell-Associated Molecule, DD1.1	Dr Barry Hock, Prof Martin Kennedy, Prof Justin Roake
Anna Chapman	Aggregation and chlorination of proteins by hypochlorous acid: Insights into reactions within neutrophils	Prof Tony Kettle, Porf Christine Winterbourn
Victoria Metcalf	The Molecular Evolution of Serum Albumin in Non-Mammalian Vertebrate Species	Prof Stephen Brennan, Prof Peter George